GREMLIN Database
Q9HRA1 - Htr6 transducer
UniProt: Q9HRA1 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 789 (652)
Sequences: 936 (838)
Seq/√Len: 32.8

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
330_D335_T6.1771.00
424_A429_D6.0831.00
344_R349_G4.5761.00
728_E732_A4.4361.00
328_A351_L3.6231.00
28_K346_D3.2301.00
527_V699_T3.1831.00
612_D615_G3.0291.00
552_A675_A3.0061.00
336_F363_Q2.9701.00
372_A376_A2.9681.00
605_N627_D2.8321.00
603_N621_V2.8221.00
351_L358_M2.7821.00
623_N627_D2.6871.00
438_A447_A2.6631.00
535_A696_S2.6231.00
328_A358_M2.5781.00
561_E663_H2.5241.00
598_N607_E2.4811.00
562_I667_G2.4751.00
611_A615_G2.4631.00
602_L626_K2.4460.99
444_R447_A2.4220.99
513_A712_R2.3690.99
586_I643_I2.3280.99
506_Q727_A2.3250.99
599_M609_A2.3130.99
434_L446_V2.2890.99
595_E606_I2.2510.99
594_A619_A2.2490.99
590_I667_G2.2440.99
580_M586_I2.2320.99
615_G619_A2.2030.99
350_R353_G2.1950.99
596_Q607_E2.1870.99
358_M362_L2.1860.99
434_L447_A2.1730.99
559_M562_I2.1460.99
351_L355_F2.1350.99
617_G624_E2.0880.98
503_A726_D2.0810.98
562_I626_K2.0620.98
25_F317_T2.0570.98
77_W81_Q2.0260.98
497_Q735_E2.0150.98
421_V450_F2.0060.98
356_D359_R2.0060.98
44_G299_V1.9960.98
643_I667_G1.9950.98
602_L619_A1.9950.98
640_E727_A1.9840.98
591_T640_E1.9830.98
530_S691_G1.9780.98
586_I642_E1.9750.98
669_S673_R1.9600.97
605_N631_E1.9520.97
521_S710_V1.9510.97
508_D515_G1.9480.97
212_N215_R1.9460.97
725_E728_E1.9410.97
324_L355_F1.9290.97
626_K737_Q1.9280.97
415_A418_Y1.9250.97
351_L362_L1.9110.97
591_T595_E1.8780.97
744_I751_L1.8500.96
528_A531_S1.8440.96
346_D349_G1.8410.96
437_D447_A1.8400.96
705_A712_R1.8270.96
373_V376_A1.8160.96
599_M605_N1.7970.96
418_Y447_A1.7850.96
273_W276_V1.7830.96
609_A620_V1.7710.95
369_A372_A1.7700.95
514_A713_V1.7670.95
562_I602_L1.7630.95
579_R670_T1.7570.95
116_V119_H1.7560.95
556_I703_A1.7290.95
511_E519_E1.7220.95
596_Q602_L1.7200.95
586_I667_G1.7050.94
580_M670_T1.7010.94
29_F317_T1.7000.94
503_A727_A1.6970.94
320_P348_V1.6950.94
495_R726_D1.6950.94
433_R458_E1.6760.94
549_R682_V1.6720.94
433_R455_D1.6660.94
579_R663_H1.6610.94
589_F724_T1.6590.93
585_D605_N1.6560.93
554_S673_R1.6550.93
619_A624_E1.6550.93
594_A611_A1.6530.93
627_D634_Q1.6510.93
85_A88_V1.6500.93
595_E723_V1.6490.93
687_D690_H1.6470.93
723_V726_D1.6320.93
149_T152_A1.6230.93
674_A678_I1.6220.93
324_L328_A1.6210.93
639_I667_G1.6200.93
415_A443_M1.6200.93
324_L351_L1.6180.93
496_I734_A1.6170.93
551_A606_I1.6140.92
231_N235_D1.6120.92
601_A610_R1.6080.92
595_E630_E1.6020.92
586_I635_A1.5970.92
580_M751_L1.5950.92
548_G734_A1.5790.92
509_D587_I1.5780.92
591_T606_I1.5680.91
503_A587_I1.5680.91
623_N633_K1.5620.91
558_D587_I1.5550.91
595_E633_K1.5490.91
623_N640_E1.5450.91
545_G549_R1.5420.91
584_G590_I1.5420.91
627_D630_E1.5400.91
429_D454_L1.5340.90
508_D513_A1.5290.90
434_L443_M1.5250.90
415_A450_F1.5240.90
620_V624_E1.5230.90
506_Q549_R1.5220.90
725_E732_A1.5180.90
84_H115_V1.5160.90
595_E626_K1.5150.90
300_V304_I1.5100.90
615_G667_G1.5070.90
328_A355_F1.5060.90
580_M660_T1.5030.90
643_I660_T1.4890.89
419_S422_M1.4820.89
626_K720_S1.4800.89
626_K642_E1.4720.88
447_A453_M1.4720.88
86_R89_S1.4650.88
612_D617_G1.4640.88
372_A375_E1.4630.88
605_N726_D1.4580.88
604_A621_V1.4570.88
552_A737_Q1.4560.88
244_A248_N1.4480.88
506_Q719_I1.4450.88
447_A450_F1.4410.87
602_L609_A1.4410.87
314_G318_V1.4340.87
430_L443_M1.4310.87
511_E515_G1.4260.87
331_I359_R1.4250.87
499_I670_T1.4210.87
243_I246_V1.4150.86
615_G620_V1.4130.86
670_T674_A1.4080.86
437_D444_R1.4050.86
605_N623_N1.4050.86
592_D623_N1.4020.86
364_D368_E1.4020.86
615_G621_V1.4020.86
609_A619_A1.4010.86
468_A471_V1.4010.86
216_R229_D1.3960.86
606_I623_N1.3950.86
506_Q607_E1.3910.85
248_N252_A1.3830.85
150_T154_P1.3820.85
367_Q371_A1.3810.85
314_G317_T1.3790.85
121_V127_T1.3720.85
355_F362_L1.3720.85
419_S449_E1.3710.85
152_A184_A1.3710.85
586_I589_F1.3680.84
520_L528_A1.3670.84
542_V546_E1.3670.84
726_D737_Q1.3650.84
520_L713_V1.3570.84
332_E541_A1.3560.84
508_D721_Q1.3500.84
493_S735_E1.3470.84
499_I607_E1.3470.84
434_L445_A1.3450.83
331_I362_L1.3440.83
548_G605_N1.3430.83
599_M678_I1.3380.83
590_I624_E1.3380.83
624_E667_G1.3360.83
98_R102_P1.3350.83
444_R448_T1.3330.83
422_M434_L1.3290.83
558_D595_E1.3210.82
506_Q706_T1.3190.82
632_T636_A1.3170.82
664_I667_G1.3170.82
562_I737_Q1.3140.82
515_G717_A1.3100.82
301_L308_I1.3010.81
594_A602_L1.2960.81
626_K631_E1.2930.81
527_V605_N1.2900.81
582_D645_A1.2860.81
371_A375_E1.2790.80
620_V667_G1.2690.80
607_E667_G1.2680.80
685_I733_A1.2620.79
122_N126_G1.2580.79
371_A374_E1.2550.79
117_S200_R1.2550.79
531_S556_I1.2540.79
426_A429_D1.2520.79
414_R438_A1.2520.79
216_R230_S1.2470.78
81_Q87_S1.2440.78
499_I579_R1.2390.78
595_E602_L1.2390.78
615_G639_I1.2360.78
33_F39_V1.2330.78
737_Q744_I1.2320.78
519_E705_A1.2280.77
319_T338_V1.2270.77
52_E56_E1.2240.77
453_M712_R1.2200.77
461_I520_L1.2150.77
607_E635_A1.2100.76
605_N664_I1.2080.76
545_G593_I1.1990.76
725_E729_Q1.1940.75
89_S187_V1.1910.75
552_A562_I1.1870.75
488_T538_A1.1800.74
527_V723_V1.1800.74
185_S198_V1.1780.74
632_T639_I1.1780.74
606_I640_E1.1730.74
678_I681_T1.1720.74
675_A737_Q1.1670.74
453_M500_A1.1650.73
562_I595_E1.1610.73
331_I351_L1.1580.73
664_I668_V1.1530.73
607_E610_R1.1490.72
505_Q716_V1.1460.72
538_A688_A1.1450.72
502_G719_I1.1420.72
502_G726_D1.1420.72
127_T130_A1.1400.72
737_Q751_L1.1400.72
339_D356_D1.1400.72
116_V202_Q1.1390.72
621_V624_E1.1350.72
630_E727_A1.1340.71
465_A748_A1.1330.71
509_D623_N1.1310.71
555_A632_T1.1300.71
521_S640_E1.1290.71
611_A622_A1.1280.71
129_V133_E1.1270.71
717_A720_S1.1260.71
510_L717_A1.1230.71
449_E596_Q1.1180.70
598_N626_K1.1150.70
562_I642_E1.1140.70
558_D723_V1.1130.70
38_V199_T1.1120.70
167_E170_Y1.1110.70
530_S627_D1.1100.70
523_S633_K1.1060.70
660_T664_I1.1050.69
199_T204_Q1.1020.69
513_A717_A1.1000.69
208_L227_V1.1000.69
678_I702_Q1.0950.69
101_A105_L1.0940.69
457_L688_A1.0880.68
587_I691_G1.0860.68
106_L110_L1.0840.68
588_E640_E1.0840.68
253_A256_T1.0830.68
231_N234_F1.0770.67
37_L518_D1.0760.67
535_A693_Q1.0750.67
221_N273_W1.0750.67
618_F622_A1.0740.67
611_A619_A1.0740.67
421_V447_A1.0730.67
105_L435_D1.0730.67
445_A449_E1.0700.67
729_Q732_A1.0700.67
609_A624_E1.0680.67
491_T717_A1.0680.67
582_D638_D1.0680.67
532_A700_E1.0670.67
606_I726_D1.0670.67
449_E737_Q1.0650.67
708_S724_T1.0650.67
356_D360_V1.0630.66
626_K751_L1.0560.66
35_V313_L1.0560.66
415_A444_R1.0560.66
74_I148_W1.0540.66
488_T727_A1.0540.66
587_I723_V1.0530.66
510_L514_A1.0520.66
214_T283_E1.0500.65
48_F291_V1.0490.65
547_A550_D1.0460.65
589_F631_E1.0410.65
606_I723_V1.0400.65
607_E626_K1.0400.65
418_Y712_R1.0380.65
195_L300_V1.0380.65
610_R671_V1.0380.65
414_R444_R1.0380.65
510_L636_A1.0360.64
598_N621_V1.0340.64
199_T203_P1.0330.64
262_V265_L1.0320.64
590_I635_A1.0310.64
555_A678_I1.0300.64
702_Q709_V1.0280.64
121_V125_R1.0260.64
535_A688_A1.0260.64
499_I667_G1.0240.63
450_F471_V1.0240.63
451_N457_L1.0220.63
530_S632_T1.0210.63
502_G595_E1.0200.63
270_H273_W1.0190.63
678_I695_I1.0180.63
596_Q619_A1.0170.63
617_G620_V1.0140.63
468_A734_A1.0130.63
579_R751_L1.0130.63
261_R335_T1.0120.63
548_G747_S1.0110.62
623_N731_S1.0100.62
408_S418_Y1.0080.62
464_V663_H1.0080.62
464_V582_D1.0060.62
642_E675_A1.0040.62
593_I603_N1.0020.62
660_T688_A0.9990.61
170_Y182_A0.9990.61
507_H721_Q0.9980.61
298_L328_A0.9970.61
674_A716_V0.9970.61
358_M527_V0.9970.61
415_A472_A0.9930.61
492_V685_I0.9930.61
660_T675_A0.9900.61
595_E614_D0.9860.60
514_A518_D0.9840.60
677_A719_I0.9810.60
619_A667_G0.9800.60
545_G631_E0.9790.60
59_T67_N0.9790.60
440_E444_R0.9780.60
555_A643_I0.9770.60
434_L450_F0.9760.60
593_I621_V0.9750.60
461_I464_V0.9750.60
516_E605_N0.9720.59
538_A675_A0.9720.59
464_V488_T0.9700.59
344_R635_A0.9680.59
583_I590_I0.9650.59
421_V434_L0.9620.59
491_T722_H0.9620.59
601_A678_I0.9600.58
531_S664_I0.9590.58
558_D720_S0.9590.58
727_A731_S0.9580.58
125_R129_V0.9570.58
591_T726_D0.9570.58
617_G638_D0.9550.58
340_L352_Y0.9520.58
721_Q725_E0.9490.57
579_R671_V0.9480.57
590_I598_N0.9450.57
607_E661_S0.9430.57
128_V152_A0.9430.57
336_F362_L0.9390.57
447_A451_N0.9380.57
495_R716_V0.9370.57
598_N603_N0.9360.56
548_G678_I0.9340.56
545_G734_A0.9330.56
626_K712_R0.9330.56
506_Q667_G0.9330.56
642_E660_T0.9320.56
609_A667_G0.9300.56
589_F667_G0.9300.56
589_F639_I0.9290.56
170_Y202_Q0.9280.56
460_T684_A0.9270.56
293_Q749_D0.9260.56
593_I631_E0.9250.56
186_S280_D0.9230.55
428_G678_I0.9230.55
83_T275_T0.9220.55
721_Q726_D0.9220.55
450_F458_E0.9210.55
590_I615_G0.9200.55
499_I506_Q0.9200.55
513_A516_E0.9190.55
533_T694_E0.9190.55
595_E717_A0.9180.55
534_V552_A0.9180.55
436_E444_R0.9170.55
328_A332_E0.9160.55
289_D305_S0.9150.55
517_M668_V0.9140.55
520_L645_A0.9120.54
172_S175_L0.9110.54
179_P186_S0.9110.54
640_E723_V0.9100.54
731_S735_E0.9090.54
118_M121_V0.9090.54
438_A527_V0.9080.54
47_A320_P0.9070.54
491_T728_E0.9070.54
527_V623_N0.9070.54
344_R359_R0.9050.54
327_R340_L0.9040.54
606_I717_A0.9030.54
170_Y273_W0.9000.53
506_Q731_S0.8980.53
509_D716_V0.8940.53
213_S219_I0.8940.53
710_V723_V0.8930.53
349_G352_Y0.8890.53
328_A331_I0.8880.52
471_V731_S0.8880.52
149_T153_V0.8880.52
592_D599_M0.8830.52
605_N688_A0.8830.52
599_M626_K0.8820.52
506_Q635_A0.8810.52
186_S198_V0.8800.52
511_E595_E0.8780.52
586_I660_T0.8770.52
325_R331_I0.8770.52
636_A724_T0.8760.51
548_G585_D0.8750.51
524_I696_S0.8750.51
181_M186_S0.8750.51
549_R588_E0.8750.51
70_E78_M0.8730.51
626_K633_K0.8710.51
500_A507_H0.8710.51
505_Q732_A0.8690.51
584_G692_I0.8680.51
581_S665_D0.8660.51
378_A459_A0.8610.50
511_E721_Q0.8600.50
602_L612_D0.8580.50
525_Q707_Q0.8580.50
264_A269_P0.8570.50
500_A510_L0.8570.50
218_T276_V0.8570.50
702_Q721_Q0.8570.50
512_R515_G0.8550.50
590_I617_G0.8540.50
334_G695_I0.8540.50
717_A724_T0.8530.50
246_V251_T0.8500.49
303_V324_L0.8500.49
456_G750_D0.8490.49
351_L361_S0.8430.49
414_R417_D0.8430.49
310_G692_I0.8410.49
642_E667_G0.8410.49
104_I109_Q0.8400.48
446_V518_D0.8390.48
507_H595_E0.8380.48
32_A315_R0.8370.48
453_M457_L0.8370.48
504_I728_E0.8330.48
524_I715_D0.8310.48
494_E550_D0.8300.48
631_E717_A0.8300.48
327_R338_V0.8280.48
558_D591_T0.8260.47
408_S411_L0.8250.47
438_A443_M0.8240.47
673_R709_V0.8220.47
283_E301_L0.8210.47
461_I748_A0.8190.47
443_M450_F0.8170.47
491_T732_A0.8160.47
552_A664_I0.8160.47
635_A702_Q0.8160.47
457_L579_R0.8140.46
601_A664_I0.8130.46
187_V205_V0.8110.46
556_I678_I0.8090.46
328_A362_L0.8080.46
591_T636_A0.8070.46
488_T585_D0.8070.46
612_D632_T0.8050.46
630_E726_D0.8040.46
414_R439_D0.8040.46
132_T140_S0.8010.45
376_A499_I0.8000.45
630_E643_I0.8000.45
551_A670_T0.8000.45
638_D733_A0.7990.45
196_V273_W0.7970.45
636_A660_T0.7970.45
660_T678_I0.7950.45
183_F196_V0.7940.45
616_D635_A0.7920.45
40_I321_L0.7920.45
493_S497_Q0.7910.44
268_T500_A0.7910.44
443_M467_F0.7880.44
130_A133_E0.7880.44
595_E605_N0.7860.44
177_D613_K0.7810.44
417_D438_A0.7810.44
247_R300_V0.7800.44
518_D522_A0.7780.43
217_T268_T0.7770.43
492_V731_S0.7760.43
627_D667_G0.7750.43
471_V685_I0.7730.43
509_D637_A0.7730.43
414_R447_A0.7720.43
614_D713_V0.7710.43
637_A716_V0.7700.43
517_M520_L0.7680.43
696_S737_Q0.7650.42
610_R717_A0.7650.42
696_S744_I0.7640.42
663_H678_I0.7640.42
612_D624_E0.7630.42
25_F321_L0.7620.42
464_V691_G0.7610.42
317_T340_L0.7610.42
230_S409_E0.7610.42
700_E708_S0.7600.42
101_A108_D0.7580.42
97_D100_A0.7580.42
495_R605_N0.7560.42
516_E737_Q0.7560.42
148_W172_S0.7530.41
329_Q350_R0.7520.41
592_D630_E0.7520.41
221_N227_V0.7510.41
321_L350_R0.7500.41
120_L320_P0.7480.41
541_A684_A0.7480.41
502_G723_V0.7480.41
127_T131_S0.7470.41
154_P163_V0.7460.41
508_D723_V0.7440.41
324_L338_V0.7440.41
538_A672_E0.7440.41
635_A667_G0.7440.41
331_I358_M0.7430.41
586_I602_L0.7430.41
152_A252_A0.7420.40
248_N275_T0.7420.40
594_A625_V0.7420.40
299_V303_V0.7400.40
212_N220_L0.7380.40
595_E631_E0.7380.40
213_S217_T0.7380.40
434_L685_I0.7370.40
541_A619_A0.7370.40
497_Q707_Q0.7370.40
644_Q737_Q0.7370.40
517_M705_A0.7360.40
508_D511_E0.7340.40
340_L356_D0.7320.40
602_L624_E0.7310.40
99_R120_L0.7310.40
321_L500_A0.7310.40
189_K192_G0.7290.39
674_A688_A0.7270.39
673_R680_D0.7270.39
55_V59_T0.7250.39
321_L351_L0.7250.39
336_F366_I0.7210.39
215_R230_S0.7200.39
505_Q509_D0.7170.38
545_G682_V0.7170.38
594_A622_A0.7170.38
631_E639_I0.7160.38
527_V606_I0.7140.38
416_A419_S0.7130.38
368_E372_A0.7130.38
128_V131_S0.7120.38
246_V249_D0.7120.38
411_L443_M0.7120.38
663_H691_G0.7110.38
523_S527_V0.7110.38
623_N630_E0.7100.38
705_A727_A0.7100.38
422_M447_A0.7100.38
556_I692_I0.7090.38
415_A446_V0.7090.38
450_F706_T0.7080.38
177_D221_N0.7070.38
457_L587_I0.7070.38
499_I723_V0.7070.38
436_E448_T0.7060.38
137_E140_S0.7060.38
678_I724_T0.7020.37
115_V119_H0.7020.37
130_A134_L0.7010.37
449_E630_E0.6990.37
588_E638_D0.6980.37
122_N202_Q0.6980.37
579_R668_V0.6980.37
332_E357_D0.6980.37
583_I623_N0.6960.37
308_I378_A0.6960.37
304_I713_V0.6960.37
636_A642_E0.6960.37
562_I720_S0.6950.37
617_G621_V0.6940.37
201_I248_N0.6930.37
512_R721_Q0.6930.37
357_D362_L0.6920.37
504_I725_E0.6920.37
418_Y436_E0.6910.36
82_R85_A0.6900.36
28_K362_L0.6890.36
58_Q63_L0.6890.36
429_D453_M0.6880.36
660_T667_G0.6870.36
585_D727_A0.6860.36
591_T720_S0.6850.36
544_R680_D0.6840.36
612_D619_A0.6830.36
109_Q151_A0.6820.36
527_V698_A0.6820.36
679_E703_A0.6820.36
328_A361_S0.6820.36
306_L321_L0.6810.36
268_T276_V0.6800.36
252_A255_T0.6800.36
515_G519_E0.6800.36
516_E548_G0.6780.35
454_L699_T0.6780.35
120_L199_T0.6780.35
45_V49_Q0.6770.35
351_L357_D0.6760.35
148_W187_V0.6760.35
727_A738_S0.6760.35
252_A258_S0.6760.35
87_S91_D0.6760.35
471_V587_I0.6750.35
534_V559_M0.6750.35
434_L514_A0.6740.35
459_A497_Q0.6740.35
55_V305_S0.6740.35
507_H591_T0.6730.35
299_V354_S0.6720.35
246_V275_T0.6710.35
105_L198_V0.6710.35
78_M297_V0.6680.35
498_E502_G0.6680.35
595_E721_Q0.6680.35
418_Y443_M0.6660.35
169_S273_W0.6650.34
518_D705_A0.6640.34
44_G298_L0.6630.34
509_D717_A0.6630.34
414_R419_S0.6630.34
580_M675_A0.6630.34
513_A671_V0.6620.34
467_F682_V0.6620.34
632_T642_E0.6620.34
506_Q610_R0.6610.34
218_T275_T0.6600.34
224_D273_W0.6600.34
81_Q92_E0.6590.34
661_S665_D0.6590.34
610_R728_E0.6590.34
434_L449_E0.6570.34
511_E591_T0.6560.34
436_E443_M0.6560.34
591_T637_A0.6560.34
489_S626_K0.6550.34
678_I737_Q0.6540.34
453_M626_K0.6540.34
531_S748_A0.6540.34
39_V349_G0.6510.33
153_V195_L0.6490.33
541_A703_A0.6480.33
579_R667_G0.6480.33
559_M667_G0.6460.33
502_G606_I0.6460.33
596_Q605_N0.6460.33
152_A155_E0.6450.33
712_R737_Q0.6450.33
153_V243_I0.6410.33
517_M713_V0.6410.33
668_V677_A0.6410.33
556_I663_H0.6400.33
588_E715_D0.6380.32
635_A675_A0.6350.32
468_A506_Q0.6340.32
524_I643_I0.6340.32
29_F44_G0.6340.32
597_T602_L0.6340.32
608_A622_A0.6330.32
411_L441_E0.6320.32
717_A723_V0.6320.32
712_R723_V0.6320.32
582_D586_I0.6320.32
32_A35_V0.6310.32
421_V548_G0.6300.32
506_Q640_E0.6280.32
607_E612_D0.6270.32
148_W151_A0.6260.32
138_G141_L0.6240.31
529_A533_T0.6230.31
220_L273_W0.6230.31
468_A528_A0.6220.31
517_M735_E0.6220.31
368_E689_N0.6220.31
531_S611_A0.6210.31
492_V635_A0.6210.31
536_E697_D0.6210.31
673_R676_A0.6200.31
720_S723_V0.6200.31
344_R356_D0.6200.31
38_V186_S0.6180.31
635_A741_V0.6180.31
213_S216_R0.6180.31
581_S663_H0.6170.31
602_L620_V0.6170.31
580_M667_G0.6170.31
591_T642_E0.6160.31
724_T731_S0.6150.31
516_E585_D0.6150.31
609_A615_G0.6150.31
489_S737_Q0.6150.31
605_N610_R0.6140.31
197_V201_I0.6140.31
562_I614_D0.6130.31
354_S361_S0.6120.31
596_Q728_E0.6120.31
669_S709_V0.6120.31
358_M605_N0.6110.31
450_F593_I0.6100.30
615_G626_K0.6090.30
589_F660_T0.6090.30
558_D730_V0.6090.30
630_E732_A0.6090.30
450_F582_D0.6090.30
182_A202_Q0.6080.30
737_Q750_D0.6070.30
734_A738_S0.6060.30
113_A117_S0.6060.30
202_Q221_N0.6060.30
510_L716_V0.6060.30
288_R292_G0.6060.30
99_R337_D0.6050.30
411_L454_L0.6050.30
229_D301_L0.6050.30
25_F39_V0.6030.30
611_A620_V0.6030.30
698_A703_A0.6030.30
117_S133_E0.6020.30
552_A734_A0.6000.30
598_N605_N0.5980.30
602_L737_Q0.5960.30
284_A321_L0.5960.30
167_E171_R0.5960.30
555_A589_F0.5940.29
242_S249_D0.5930.29
587_I636_A0.5930.29
591_T635_A0.5920.29
630_E667_G0.5920.29
440_E453_M0.5920.29
636_A640_E0.5920.29
119_H200_R0.5920.29
251_T300_V0.5910.29
513_A637_A0.5910.29
518_D585_D0.5900.29
471_V498_E0.5900.29
595_E625_V0.5900.29
415_A447_A0.5890.29
514_A705_A0.5890.29
617_G639_I0.5890.29
588_E737_Q0.5890.29
224_D229_D0.5860.29
242_S246_V0.5860.29
735_E746_R0.5860.29
186_S267_A0.5860.29
265_L269_P0.5850.29
544_R684_A0.5850.29
585_D741_V0.5850.29
56_E262_V0.5850.29
593_I734_A0.5840.29
502_G728_E0.5840.29
506_Q606_I0.5810.28
623_N716_V0.5810.28
510_L552_A0.5810.28
520_L535_A0.5800.28
539_A542_V0.5800.28
273_W280_D0.5790.28
621_V625_V0.5790.28
114_D268_T0.5790.28
555_A599_M0.5790.28
493_S636_A0.5770.28
493_S523_S0.5760.28
102_P181_M0.5760.28
503_A723_V0.5760.28
616_D623_N0.5760.28
590_I607_E0.5750.28
148_W169_S0.5740.28
534_V610_R0.5740.28
603_N617_G0.5740.28
447_A514_A0.5740.28
41_A45_V0.5730.28
461_I753_D0.5730.28
450_F605_N0.5730.28
489_S686_E0.5730.28
514_A716_V0.5730.28
706_T723_V0.5720.28
138_G143_E0.5710.28
545_G643_I0.5710.28
599_M688_A0.5700.28
418_Y422_M0.5680.28
558_D596_Q0.5680.28
88_V378_A0.5680.28
524_I710_V0.5680.28
635_A661_S0.5680.28
155_E305_S0.5670.28
133_E136_I0.5670.28
440_E545_G0.5670.28
215_R224_D0.5670.28
324_L340_L0.5660.27
30_A70_E0.5650.27
43_A298_L0.5640.27
167_E172_S0.5640.27
591_T732_A0.5630.27
582_D606_I0.5620.27
364_D367_Q0.5600.27
443_M598_N0.5590.27
541_A607_E0.5570.27
169_S267_A0.5570.27
464_V556_I0.5570.27
355_F358_M0.5570.27
270_H276_V0.5560.27
548_G591_T0.5560.27
307_A352_Y0.5560.27
548_G674_A0.5550.27
502_G727_A0.5550.27
57_H326_N0.5540.27
125_R131_S0.5530.27
523_S691_G0.5530.27
595_E720_S0.5530.27
606_I716_V0.5520.27
46_F313_L0.5520.27
445_A460_T0.5510.26
625_V636_A0.5510.26
716_V727_A0.5510.26
436_E558_D0.5500.26
358_M730_V0.5500.26
412_Q443_M0.5490.26
111_L114_D0.5490.26
516_E631_E0.5490.26
534_V579_R0.5480.26
305_S308_I0.5480.26
504_I681_T0.5480.26
616_D619_A0.5470.26
553_E747_S0.5460.26
589_F616_D0.5450.26
732_A735_E0.5450.26
701_D716_V0.5440.26
44_G48_F0.5410.26
602_L701_D0.5400.26
532_A535_A0.5400.26
439_D641_S0.5380.26
595_E726_D0.5380.26
197_V202_Q0.5380.26
586_I721_Q0.5370.26
131_S136_I0.5370.26
589_F681_T0.5360.26
611_A621_V0.5350.25
23_R28_K0.5350.25
509_D723_V0.5350.25
527_V726_D0.5350.25
586_I620_V0.5350.25
77_W284_A0.5340.25
496_I707_Q0.5330.25
298_L330_D0.5320.25
507_H512_R0.5320.25
507_H717_A0.5320.25
225_E235_D0.5310.25
372_A498_E0.5310.25
499_I516_E0.5310.25
355_F369_A0.5310.25
168_Q220_L0.5300.25
172_S176_N0.5280.25
601_A674_A0.5280.25
503_A660_T0.5270.25
579_R630_E0.5260.25
640_E705_A0.5260.25
741_V751_L0.5250.25
30_A33_F0.5250.25
463_Q491_T0.5250.25
695_I709_V0.5240.25
527_V706_T0.5240.25
373_V677_A0.5240.25
596_Q692_I0.5240.25
334_G428_G0.5240.25
527_V671_V0.5230.25
514_A619_A0.5220.25
121_V129_V0.5210.25
122_N182_A0.5210.25
218_T260_G0.5210.25
352_Y358_M0.5210.25
636_A717_A0.5210.25
419_S563_E0.5200.25
410_R414_R0.5200.25
497_Q713_V0.5190.24
592_D634_Q0.5190.24
606_I633_K0.5180.24
588_E722_H0.5180.24
28_K33_F0.5180.24
492_V705_A0.5180.24
198_V203_P0.5170.24
595_E599_M0.5170.24
85_A121_V0.5170.24
359_R363_Q0.5160.24
453_M548_G0.5160.24
48_F51_T0.5150.24
440_E443_M0.5140.24
453_M496_I0.5140.24
559_M642_E0.5140.24
705_A708_S0.5130.24
453_M727_A0.5110.24
587_I593_I0.5110.24
187_V196_V0.5110.24
226_P231_N0.5110.24
31_V699_T0.5100.24
33_F280_D0.5100.24
555_A639_I0.5100.24
347_E629_A0.5100.24
25_F294_T0.5090.24
120_L187_V0.5090.24
471_V640_E0.5090.24
586_I737_Q0.5090.24
726_D730_V0.5080.24
370_E374_E0.5080.24
131_S135_A0.5070.24
671_V688_A0.5060.24
489_S712_R0.5060.24
488_T636_A0.5060.24
454_L645_A0.5050.24
31_V302_A0.5040.24
535_A734_A0.5040.24
496_I696_S0.5030.24
491_T736_E0.5030.24
284_A295_V0.5030.24
91_D95_R0.5020.23
579_R661_S0.5020.23
457_L630_E0.5020.23
430_L528_A0.5010.23
555_A706_T0.5000.23
358_M361_S0.5000.23
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
3zx6A 2 0.384 100 0.627 Contact Map
1qu7A 2 0.2877 100 0.688 Contact Map
2ch7A 2 0.3916 100 0.699 Contact Map
3g67A 2 0.2649 100 0.758 Contact Map
4i3mA 2 0.1888 99.9 0.861 Contact Map
3c8cA 2 0.2928 99.8 0.884 Contact Map
3lifA 1 0.2915 99.8 0.886 Contact Map
3licA 2 0.2852 99.7 0.89 Contact Map
3lidA 2 0.3029 99.7 0.891 Contact Map
3e4oA 2 0.27 99.7 0.892 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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