Q9HRA0 - HALSA - GREMLIN Contacts

Home
GREMLIN
- Submit - Monomer
- Submit - Complex
Contacts
Metagenomics
- Contacts
- Structures
Structures
- List
Old Projects
- Complexes (2014)
- PFAM (2013)

Q9HRA0 - ABC transporter (Lipoprotein)

UniProt:	Q9HRA0	Sequences: MVYALGGLDDRSFNDAANRGAQRARLDHGIAYTNHEPDSIAELGETQATLAASSNPAYDLVCCVGFRQADGLESAAAAAPDQQFMIVDTAVDASNVASYVFEEQTGSFQAGRLAALLTTRDIDAGGGATNPDARTVGFVGGVDEPLTHGFHAGFQAGVTHTASDIDVLAAYIGDFEDVEAARTAAAAMYDAGADIVYHAAGGAGVGVLQAAQANGRYAIGVDSDQSRSNPRYADVVLASMVKRIDTAVYDAIEATIDGDLPAGDVVSLGLATNGVSVQYGTQLGPAIPDAVTDALGETREALVAGDITVPTERPQSAGGGGV	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	322 (285)
Sequences:	3613 (2567)
Seq/√Len:	152.0

BACSU - MED YUFN
HALSA - Q9HRA0 Q9HR20

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
301_A	306_D	4.581	1.00
108_F	160_H	3.740	1.00
63_C	72_L	3.355	1.00
300_E	304_A	3.345	1.00
289_D	293_D	3.276	1.00
158_V	165_I	3.156	1.00
253_E	257_D	3.113	1.00
134_R	162_A	2.918	1.00
297_E	301_A	2.842	1.00
112_R	298_T	2.613	1.00
189_Y	216_R	2.581	1.00
172_I	203_A	2.525	1.00
136_V	158_V	2.522	1.00
116_L	294_A	2.506	1.00
47_Q	74_S	2.503	1.00
156_A	310_P	2.468	1.00
15_D	19_R	2.467	1.00
118_T	134_R	2.460	1.00
299_R	303_V	2.452	1.00
135_T	166_D	2.424	1.00
135_T	168_L	2.410	1.00
51_A	78_A	2.409	1.00
27_D	249_Y	2.391	1.00
9_D	15_D	2.333	1.00
23_R	249_Y	2.180	1.00
118_T	194_D	2.114	1.00
143_D	148_H	2.077	1.00
269_G	272_T	2.077	1.00
294_A	297_E	2.075	1.00
288_P	291_V	2.071	1.00
54_S	84_F	1.954	1.00
117_L	288_P	1.916	1.00
54_S	79_A	1.906	1.00
106_G	240_M	1.903	1.00
296_G	299_R	1.893	1.00
22_Q	25_R	1.864	1.00
112_R	161_T	1.854	1.00
296_G	300_E	1.852	1.00
292_T	296_G	1.840	1.00
110_A	277_V	1.830	1.00
139_V	207_V	1.829	1.00
135_T	193_A	1.792	1.00
51_A	79_A	1.745	1.00
23_R	27_D	1.722	1.00
18_N	22_Q	1.702	1.00
293_D	297_E	1.697	1.00
112_R	160_H	1.695	1.00
250_D	254_A	1.684	1.00
101_F	247_A	1.682	1.00
160_H	298_T	1.676	1.00
61_V	82_Q	1.675	1.00
276_S	299_R	1.656	1.00
113_L	295_L	1.652	1.00
103_E	149_G	1.623	1.00
300_E	303_V	1.623	1.00
190_D	214_N	1.608	1.00
174_D	177_D	1.589	1.00
181_A	203_A	1.568	1.00
102_E	269_G	1.564	1.00
155_Q	159_T	1.562	1.00
301_A	307_I	1.560	1.00
289_D	292_T	1.559	1.00
151_H	155_Q	1.552	1.00
110_A	219_I	1.536	1.00
270_L	303_V	1.517	1.00
24_A	252_I	1.514	1.00
117_L	291_V	1.505	1.00
22_Q	26_L	1.486	1.00
115_A	165_I	1.462	1.00
182_R	213_A	1.445	1.00
115_A	118_T	1.438	1.00
182_R	186_A	1.427	1.00
168_L	193_A	1.426	1.00
178_V	203_A	1.420	1.00
24_A	28_H	1.390	1.00
185_A	196_V	1.388	1.00
220_G	225_Q	1.366	1.00
28_H	249_Y	1.362	1.00
294_A	298_T	1.338	1.00
254_A	259_D	1.320	1.00
189_Y	211_A	1.319	1.00
301_A	304_A	1.291	1.00
273_N	276_S	1.276	1.00
91_V	98_S	1.276	1.00
102_E	105_T	1.262	1.00
35_H	53_S	1.242	1.00
293_D	296_G	1.238	1.00
182_R	209_Q	1.233	1.00
186_A	190_D	1.216	1.00
28_H	253_E	1.202	1.00
140_G	147_T	1.189	1.00
243_R	246_T	1.186	1.00
50_L	63_C	1.186	1.00
109_Q	299_R	1.181	1.00
17_A	248_V	1.179	1.00
8_L	34_N	1.179	1.00
69_A	89_T	1.172	1.00
110_A	240_M	1.171	1.00
105_T	271_A	1.168	1.00
77_A	93_A	1.168	1.00
108_F	298_T	1.167	1.00
23_R	245_D	1.143	1.00
118_T	195_I	1.143	1.00
51_A	75_A	1.131	1.00
208_L	236_V	1.130	1.00
172_I	184_A	1.125	1.00
47_Q	51_A	1.120	0.99
115_A	161_T	1.119	0.99
73_E	77_A	1.117	0.99
60_L	252_I	1.113	0.99
106_G	275_V	1.108	0.99
118_T	158_V	1.094	0.99
19_R	22_Q	1.090	0.99
113_L	238_A	1.089	0.99
118_T	133_A	1.085	0.99
97_A	260_L	1.084	0.99
135_T	192_G	1.083	0.99
109_Q	295_L	1.080	0.99
170_A	188_M	1.078	0.99
51_A	55_N	1.076	0.99
133_A	194_D	1.065	0.99
116_L	291_V	1.057	0.99
25_R	31_A	1.054	0.99
183_T	186_A	1.050	0.99
298_T	301_A	1.049	0.99
249_Y	253_E	1.046	0.99
76_A	93_A	1.045	0.99
57_A	82_Q	1.037	0.99
207_V	218_A	1.030	0.99
215_G	235_V	1.030	0.99
53_S	58_Y	1.029	0.99
33_T	58_Y	1.026	0.99
113_L	287_I	1.021	0.99
250_D	253_E	1.013	0.99
137_G	193_A	1.009	0.99
27_D	253_E	1.005	0.99
137_G	188_M	1.002	0.99
186_A	210_A	1.001	0.99
50_L	75_A	1.000	0.99
37_P	49_T	0.998	0.99
8_L	18_N	0.993	0.99
217_Y	237_L	0.985	0.99
97_A	266_V	0.985	0.99
93_A	96_V	0.984	0.99
238_A	278_Q	0.982	0.99
238_A	279_Y	0.980	0.99
177_D	180_A	0.978	0.99
64_V	87_V	0.964	0.98
54_S	82_Q	0.960	0.98
18_N	34_N	0.957	0.98
243_R	276_S	0.957	0.98
246_T	250_D	0.954	0.98
51_A	54_S	0.950	0.98
212_Q	234_D	0.947	0.98
189_Y	196_V	0.944	0.98
210_A	213_A	0.942	0.98
39_S	42_E	0.939	0.98
112_R	294_A	0.938	0.98
218_A	235_V	0.935	0.98
208_L	218_A	0.934	0.98
47_Q	75_A	0.933	0.98
102_E	267_S	0.932	0.98
86_I	89_T	0.932	0.98
284_G	292_T	0.928	0.98
217_Y	286_A	0.928	0.98
170_A	184_A	0.927	0.98
241_V	276_S	0.927	0.98
195_I	219_I	0.922	0.98
172_I	181_A	0.914	0.98
186_A	214_N	0.910	0.98
162_A	165_I	0.907	0.98
83_Q	260_L	0.906	0.98
155_Q	167_V	0.906	0.98
37_P	40_I	0.905	0.98
92_D	98_S	0.899	0.98
20_G	245_D	0.895	0.98
107_S	150_F	0.894	0.98
69_A	73_E	0.893	0.97
60_L	255_T	0.886	0.97
168_L	191_A	0.885	0.97
60_L	85_M	0.885	0.97
197_Y	240_M	0.878	0.97
180_A	183_T	0.875	0.97
117_L	237_L	0.874	0.97
112_R	116_L	0.873	0.97
59_D	82_Q	0.873	0.97
158_V	167_V	0.872	0.97
62_C	85_M	0.866	0.97
298_T	307_I	0.858	0.97
50_L	72_L	0.851	0.97
133_A	192_G	0.848	0.97
208_L	235_V	0.847	0.97
297_E	300_E	0.846	0.97
300_E	306_D	0.844	0.96
70_D	73_E	0.838	0.96
220_G	239_S	0.837	0.96
55_N	79_A	0.837	0.96
25_R	32_Y	0.831	0.96
73_E	96_V	0.831	0.96
102_E	272_T	0.828	0.96
188_M	193_A	0.820	0.96
211_A	218_A	0.818	0.96
85_M	99_Y	0.817	0.96
226_S	278_Q	0.815	0.96
73_E	93_A	0.815	0.96
210_A	214_N	0.814	0.96
83_Q	255_T	0.812	0.96
37_P	42_E	0.800	0.95
107_S	240_M	0.800	0.95
268_L	272_T	0.797	0.95
117_L	195_I	0.795	0.95
254_A	257_D	0.794	0.95
114_A	219_I	0.790	0.95
218_A	236_V	0.790	0.95
155_Q	169_A	0.786	0.95
273_N	303_V	0.781	0.95
54_S	75_A	0.775	0.94
283_L	286_A	0.774	0.94
115_A	162_A	0.773	0.94
134_R	194_D	0.773	0.94
290_A	293_D	0.773	0.94
253_E	256_I	0.771	0.94
72_L	96_V	0.771	0.94
151_H	169_A	0.763	0.94
21_A	25_R	0.760	0.94
21_A	32_Y	0.760	0.94
6_G	14_N	0.759	0.94
138_F	151_H	0.759	0.94
297_E	306_D	0.758	0.94
113_L	219_I	0.758	0.94
112_R	158_V	0.757	0.94
302_L	307_I	0.745	0.93
23_R	246_T	0.739	0.93
8_L	15_D	0.738	0.93
222_D	242_K	0.737	0.93
101_F	242_K	0.737	0.93
138_F	199_A	0.736	0.93
11_R	228_S	0.736	0.93
150_F	199_A	0.735	0.93
290_A	294_A	0.732	0.92
87_V	244_I	0.727	0.92
17_A	244_I	0.726	0.92
183_T	187_A	0.719	0.92
50_L	54_S	0.718	0.92
50_L	68_Q	0.718	0.92
81_D	94_S	0.717	0.92
88_D	242_K	0.716	0.92
179_E	182_R	0.712	0.91
115_A	134_R	0.710	0.91
116_L	161_T	0.708	0.91
195_I	237_L	0.708	0.91
5_L	176_E	0.708	0.91
24_A	249_Y	0.703	0.91
20_G	24_A	0.702	0.91
19_R	223_S	0.702	0.91
118_T	165_I	0.701	0.91
180_A	184_A	0.700	0.91
134_R	164_D	0.700	0.91
24_A	32_Y	0.698	0.91
150_F	221_V	0.698	0.91
119_T	133_A	0.697	0.91
224_D	279_Y	0.697	0.91
97_A	251_A	0.695	0.90
141_G	201_G	0.691	0.90
28_H	256_I	0.690	0.90
209_Q	212_Q	0.687	0.90
185_A	189_Y	0.686	0.90
241_V	278_Q	0.685	0.90
105_T	269_G	0.682	0.90
219_I	238_A	0.682	0.90
150_F	222_D	0.682	0.90
16_A	245_D	0.680	0.89
199_A	221_V	0.679	0.89
99_Y	251_A	0.678	0.89
55_N	78_A	0.673	0.89
103_E	240_M	0.668	0.89
160_H	163_S	0.667	0.89
221_V	242_K	0.665	0.88
34_N	38_D	0.665	0.88
139_V	185_A	0.665	0.88
251_A	254_A	0.664	0.88
108_F	157_G	0.663	0.88
113_L	117_L	0.660	0.88
186_A	213_A	0.659	0.88
151_H	171_Y	0.658	0.88
40_I	67_R	0.656	0.88
143_D	173_G	0.652	0.87
270_L	302_L	0.652	0.87
62_C	252_I	0.651	0.87
107_S	197_Y	0.649	0.87
287_I	291_V	0.649	0.87
261_P	264_D	0.649	0.87
18_N	32_Y	0.649	0.87
146_L	149_G	0.648	0.87
107_S	199_A	0.647	0.87
69_A	91_V	0.647	0.87
24_A	30_I	0.646	0.87
103_E	242_K	0.646	0.87
159_T	163_S	0.646	0.87
157_G	160_H	0.645	0.87
18_N	21_A	0.645	0.87
69_A	86_I	0.641	0.87
75_A	78_A	0.641	0.87
104_Q	309_V	0.641	0.87
140_G	171_Y	0.641	0.87
198_H	207_V	0.639	0.86
99_Y	268_L	0.639	0.86
277_V	295_L	0.639	0.86
236_V	239_S	0.637	0.86
208_L	229_N	0.637	0.86
156_A	159_T	0.634	0.86
140_G	151_H	0.632	0.86
23_R	26_L	0.631	0.86
119_T	164_D	0.630	0.86
109_Q	270_L	0.629	0.86
46_T	68_Q	0.628	0.85
74_S	78_A	0.628	0.85
229_N	235_V	0.628	0.85
42_E	48_A	0.623	0.85
184_A	188_M	0.623	0.85
287_I	292_T	0.623	0.85
212_Q	235_V	0.622	0.85
85_M	251_A	0.621	0.85
58_Y	82_Q	0.621	0.85
90_A	100_V	0.621	0.85
17_A	64_V	0.619	0.85
246_T	249_Y	0.619	0.85
26_L	81_D	0.619	0.85
108_F	112_R	0.618	0.84
255_T	260_L	0.616	0.84
273_N	299_R	0.616	0.84
206_G	210_A	0.615	0.84
25_R	28_H	0.614	0.84
112_R	295_L	0.613	0.84
92_D	264_D	0.612	0.84
291_V	295_L	0.610	0.84
38_D	42_E	0.609	0.84
226_S	234_D	0.607	0.83
110_A	238_A	0.606	0.83
270_L	299_R	0.604	0.83
104_Q	149_G	0.603	0.83
47_Q	71_G	0.603	0.83
250_D	272_T	0.603	0.83
117_L	217_Y	0.602	0.83
284_G	287_I	0.601	0.83
52_A	56_P	0.601	0.83
64_V	99_Y	0.597	0.82
90_A	98_S	0.593	0.82
25_R	30_I	0.592	0.82
224_D	278_Q	0.592	0.82
269_G	274_G	0.591	0.82
200_A	206_G	0.590	0.82
181_A	206_G	0.588	0.81
36_E	42_E	0.588	0.81
189_Y	210_A	0.584	0.81
234_D	285_P	0.581	0.81
254_A	266_V	0.580	0.81
98_S	264_D	0.580	0.81
250_D	268_L	0.580	0.81
283_L	287_I	0.576	0.80
181_A	204_G	0.574	0.80
6_G	10_D	0.574	0.80
160_H	301_A	0.573	0.80
30_I	252_I	0.573	0.80
97_A	261_P	0.571	0.80
211_A	216_R	0.571	0.80
254_A	261_P	0.569	0.79
19_R	245_D	0.567	0.79
86_I	91_V	0.567	0.79
37_P	41_A	0.566	0.79
117_L	287_I	0.566	0.79
204_G	221_V	0.563	0.79
200_A	204_G	0.562	0.79
152_A	312_E	0.562	0.79
113_L	116_L	0.560	0.78
283_L	292_T	0.560	0.78
148_H	171_Y	0.558	0.78
227_R	234_D	0.557	0.78
5_L	67_R	0.555	0.78
119_T	217_Y	0.554	0.78
154_F	197_Y	0.552	0.77
107_S	146_L	0.551	0.77
139_V	198_H	0.551	0.77
100_V	267_S	0.548	0.77
84_F	95_N	0.547	0.77
113_L	291_V	0.547	0.77
138_F	147_T	0.546	0.77
83_Q	97_A	0.545	0.76
154_F	157_G	0.545	0.76
34_N	37_P	0.545	0.76
24_A	256_I	0.544	0.76
136_V	165_I	0.544	0.76
135_T	191_A	0.543	0.76
146_L	197_Y	0.542	0.76
142_V	175_F	0.539	0.76
97_A	254_A	0.539	0.76
136_V	154_F	0.538	0.75
16_A	19_R	0.538	0.75
137_G	185_A	0.536	0.75
66_F	175_F	0.535	0.75
156_A	160_H	0.535	0.75
225_Q	228_S	0.535	0.75
189_Y	214_N	0.534	0.75
161_T	165_I	0.532	0.75
168_L	188_M	0.526	0.74
152_A	156_A	0.525	0.74
150_F	242_K	0.523	0.73
291_V	294_A	0.523	0.73
87_V	248_V	0.522	0.73
74_S	77_A	0.521	0.73
285_P	289_D	0.520	0.73
246_T	274_G	0.520	0.73
247_A	274_G	0.518	0.73
202_G	205_V	0.517	0.73
19_R	23_R	0.515	0.72
200_A	203_A	0.513	0.72
61_V	84_F	0.513	0.72
33_T	56_P	0.511	0.72
63_C	68_Q	0.510	0.72
60_L	83_Q	0.508	0.71
59_D	81_D	0.507	0.71
75_A	84_F	0.506	0.71
32_Y	39_S	0.506	0.71
234_D	286_A	0.502	0.70
53_S	61_V	0.502	0.70
226_S	283_L	0.502	0.70
224_D	239_S	0.501	0.70
182_R	210_A	0.500	0.70

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
3s99A	1	0.9193	100	0.37	Contact Map
4pevA	1	0.9627	100	0.39	Contact Map
4iilA	1	0.9286	100	0.432	Contact Map
2fqxA	1	0.9286	100	0.433	Contact Map
4p98A	1	0.9006	100	0.436	Contact Map
2hqbA	1	0.8634	100	0.468	Contact Map
4ycsA	1	0.3571	100	0.616	Contact Map
4wzzA	1	0.8571	99.6	0.773	Contact Map
4pe6A	1	0.8789	99.5	0.788	Contact Map
5braA	1	0.8354	99.4	0.804	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.0096 seconds.