Q9HR86 - HALSA - GREMLIN Contacts

Home
GREMLIN
- Submit - Monomer
- Submit - Complex
Contacts
Metagenomics
- Contacts
- Structures
Structures
- List
Old Projects
- Complexes (2014)
- PFAM (2013)

Q9HR86 - Uncharacterized protein

UniProt:	Q9HR86	Sequences: MDVLVAGAHGRVGQHLTERLADDGHHVRGMIRDPAQTDTIDGLGATPVVADLTDDVADAVAGCDGVVFAAGSRGEALDAVDRDGAIRLLSAAEDAAVDRFVMLSSMGADDPSRGPEDLRSYLAAKADADARLRESPVAHTIVRPGSLTTDAGTGRVTVADTLDPAAGSIPCADVAQTLAAALTAPAARDTTFEVLAGDTPVAEAVASVGD	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	210 (204)
Sequences:	55686 (38732)
Seq/√Len:	2711.8

ECOLI - YBJS RMLB1 GALE GM4D RMLB2 YFCH QOR2 YEEZ HLDD YRAR FCL RMLD YBJT ARNA
BACSU - YHFK YWNB GALE YTCB YHEG YFNG RMLB YFHF SPSK YTBQ YESF
HALSA - Q9HR86 Q9HML4 Q9HSV1 Q9HNV3 Q9HSU9 Q9HSE7 Q9HRD1 Q9HS50 Q9HSQ3 Q9HPF1
SULSO - Q7LXE8 Q97VN5 Q97XG1 Q97XJ9 Q980W1 Q7LXG5 Q97UM3 Q7LX44

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
8_A	29_G	3.174	1.00
2_D	26_H	2.680	1.00
19_R	176_Q	2.625	1.00
177_T	194_V	2.534	1.00
79_A	83_D	2.521	1.00
65_G	182_L	2.369	1.00
30_M	50_A	2.307	1.00
57_A	94_D	2.249	1.00
99_R	138_A	2.165	1.00
28_R	63_C	2.141	1.00
19_R	179_A	2.078	1.00
19_R	23_D	2.067	1.00
4_L	63_C	1.998	1.00
103_L	178_L	1.951	1.00
144_P	178_L	1.922	1.00
68_F	102_M	1.906	1.00
28_R	46_T	1.888	1.00
202_A	206_A	1.866	1.00
2_D	28_R	1.843	1.00
50_A	55_D	1.841	1.00
5_V	17_T	1.830	1.00
23_D	183_T	1.827	1.00
67_V	182_L	1.818	1.00
28_R	48_V	1.754	1.00
132_L	139_H	1.734	1.00
6_A	68_F	1.709	1.00
26_H	46_T	1.691	1.00
16_L	175_A	1.676	1.00
142_V	181_A	1.671	1.00
176_Q	180_A	1.642	1.00
86_I	131_R	1.610	1.00
86_I	90_S	1.599	1.00
200_P	203_E	1.586	1.00
179_A	183_T	1.579	1.00
23_D	179_A	1.572	1.00
57_A	91_A	1.569	1.00
64_D	98_D	1.557	1.00
85_A	128_A	1.496	1.00
19_R	22_D	1.493	1.00
104_S	108_A	1.487	1.00
53_T	79_A	1.486	1.00
83_D	86_I	1.486	1.00
69_A	103_L	1.485	1.00
126_A	130_A	1.468	1.00
16_L	67_V	1.462	1.00
3_V	25_H	1.451	1.00
25_H	183_T	1.436	1.00
78_D	127_D	1.413	1.00
16_L	69_A	1.408	1.00
57_A	95_A	1.403	1.00
9_H	31_I	1.395	1.00
12_V	147_L	1.391	1.00
203_E	206_A	1.388	1.00
17_T	29_G	1.384	1.00
99_R	140_T	1.383	1.00
93_E	135_S	1.374	1.00
19_R	175_A	1.350	1.00
180_A	184_A	1.349	1.00
109_D	193_E	1.345	1.00
55_D	58_D	1.342	1.00
75_E	79_A	1.342	1.00
52_L	84_G	1.284	1.00
66_V	92_A	1.266	1.00
33_D	36_Q	1.257	1.00
167_G	197_G	1.249	1.00
88_L	100_F	1.246	1.00
81_D	124_A	1.244	1.00
103_L	144_P	1.239	1.00
67_V	178_L	1.235	1.00
33_D	47_P	1.233	1.00
102_M	132_L	1.230	1.00
8_A	17_T	1.220	1.00
142_V	178_L	1.220	1.00
29_G	45_A	1.218	1.00
92_A	100_F	1.214	1.00
4_L	30_M	1.213	1.00
130_A	133_R	1.206	1.00
143_R	191_T	1.203	1.00
165_A	199_T	1.199	1.00
3_V	65_G	1.195	1.00
90_S	93_E	1.195	1.00
19_R	172_A	1.187	1.00
21_A	45_A	1.185	1.00
144_P	174_V	1.183	1.00
58_D	61_A	1.179	1.00
114_G	117_D	1.179	1.00
3_V	20_L	1.171	1.00
123_A	127_D	1.151	1.00
56_V	91_A	1.147	1.00
121_Y	125_K	1.146	1.00
52_L	70_A	1.143	1.00
92_A	97_V	1.139	1.00
169_I	174_V	1.135	1.00
102_M	128_A	1.129	1.00
171_C	175_A	1.129	1.00
61_A	95_A	1.127	1.00
15_H	172_A	1.124	1.00
11_R	149_T	1.119	1.00
80_V	84_G	1.117	1.00
129_D	143_R	1.102	1.00
18_E	22_D	1.101	1.00
138_A	188_R	1.081	1.00
6_A	88_L	1.079	1.00
133_R	141_I	1.078	1.00
89_L	100_F	1.075	1.00
101_V	142_V	1.073	1.00
66_V	88_L	1.071	1.00
148_T	170_P	1.071	1.00
133_R	191_T	1.058	1.00
69_A	178_L	1.057	1.00
102_M	141_I	1.048	1.00
72_S	80_V	1.043	1.00
68_F	85_A	1.037	1.00
20_L	179_A	1.031	1.00
143_R	193_E	1.019	1.00
83_D	87_R	1.015	1.00
163_D	202_A	1.013	1.00
151_A	154_G	1.012	1.00
21_A	44_G	1.012	1.00
34_P	49_V	1.011	1.00
60_V	66_V	1.010	1.00
57_A	61_A	1.008	1.00
157_T	160_D	1.004	1.00
147_L	174_V	1.003	1.00
60_V	63_C	0.993	1.00
90_S	94_D	0.982	1.00
104_S	129_D	0.978	1.00
173_D	196_A	0.970	1.00
82_R	127_D	0.957	1.00
2_D	63_C	0.952	1.00
163_D	200_P	0.946	1.00
28_R	62_G	0.944	1.00
48_V	59_A	0.934	1.00
30_M	56_V	0.933	1.00
36_Q	40_I	0.928	1.00
87_R	90_S	0.928	1.00
60_V	95_A	0.928	1.00
78_D	82_R	0.927	1.00
31_I	47_P	0.922	1.00
39_T	42_G	0.918	1.00
11_R	171_C	0.913	1.00
16_L	20_L	0.912	1.00
30_M	59_A	0.911	1.00
140_T	181_A	0.906	1.00
60_V	91_A	0.905	1.00
176_Q	179_A	0.898	1.00
93_E	137_V	0.892	1.00
91_A	95_A	0.891	1.00
15_H	18_E	0.891	1.00
170_P	173_D	0.889	1.00
100_F	132_L	0.887	1.00
156_V	160_D	0.874	1.00
98_D	138_A	0.874	1.00
38_D	41_D	0.865	1.00
77_L	124_A	0.860	1.00
66_V	100_F	0.852	1.00
106_M	145_G	0.850	1.00
15_H	171_C	0.846	1.00
78_D	83_D	0.840	1.00
2_D	64_D	0.840	1.00
55_D	59_A	0.836	1.00
17_T	27_V	0.836	1.00
91_A	94_D	0.832	1.00
133_R	139_H	0.831	1.00
32_R	51_D	0.828	1.00
36_Q	39_T	0.827	1.00
56_V	87_R	0.826	1.00
2_D	25_H	0.821	1.00
180_A	183_T	0.820	1.00
152_G	156_V	0.819	1.00
37_T	41_D	0.817	1.00
93_E	136_P	0.811	1.00
155_R	159_A	0.805	1.00
72_S	76_A	0.804	1.00
15_H	19_R	0.801	1.00
89_L	132_L	0.790	1.00
21_A	27_V	0.785	1.00
145_G	195_L	0.782	1.00
30_M	55_D	0.781	1.00
128_A	132_L	0.780	1.00
150_D	170_P	0.778	1.00
175_A	179_A	0.770	1.00
152_G	160_D	0.769	1.00
26_H	44_G	0.767	1.00
25_H	64_D	0.766	1.00
65_G	99_R	0.764	1.00
6_A	70_A	0.759	1.00
16_L	178_L	0.756	1.00
85_A	132_L	0.753	1.00
152_G	155_R	0.752	1.00
89_L	131_R	0.751	1.00
3_V	67_V	0.751	1.00
147_L	169_I	0.748	1.00
141_I	191_T	0.745	1.00
152_G	157_T	0.744	1.00
38_D	42_G	0.743	1.00
139_H	189_D	0.742	1.00
33_D	49_V	0.736	1.00
78_D	123_A	0.728	1.00
151_A	160_D	0.725	1.00
39_T	43_L	0.723	1.00
112_S	116_E	0.722	1.00
60_V	92_A	0.718	1.00
72_S	77_L	0.715	1.00
165_A	200_P	0.714	1.00
151_A	156_V	0.712	1.00
20_L	182_L	0.709	1.00
87_R	91_A	0.706	1.00
53_T	80_V	0.703	1.00
3_V	182_L	0.701	1.00
155_R	160_D	0.701	1.00
99_R	185_P	0.700	1.00
152_G	159_A	0.693	1.00
154_G	158_V	0.688	1.00
127_D	130_A	0.687	1.00
142_V	194_V	0.687	1.00
185_P	188_R	0.686	1.00
4_L	50_A	0.686	1.00
127_D	131_R	0.680	1.00
90_S	131_R	0.679	1.00
123_A	130_A	0.678	1.00
107_G	122_L	0.678	1.00
151_A	157_T	0.675	1.00
4_L	60_V	0.673	1.00
141_I	189_D	0.665	1.00
85_A	89_L	0.662	1.00
162_L	202_A	0.660	1.00
76_A	80_V	0.659	1.00
12_V	174_V	0.655	1.00
154_G	159_A	0.655	1.00
153_T	157_T	0.653	1.00
108_A	143_R	0.649	1.00
33_D	38_D	0.641	1.00
15_H	175_A	0.641	1.00
151_A	155_R	0.639	1.00
60_V	88_L	0.638	1.00
167_G	196_A	0.635	1.00
76_A	79_A	0.634	1.00
144_P	147_L	0.632	1.00
68_F	88_L	0.632	1.00
36_Q	41_D	0.631	1.00
156_V	159_A	0.629	1.00
142_V	177_T	0.622	1.00
51_D	54_D	0.615	1.00
23_D	176_Q	0.613	1.00
14_Q	18_E	0.613	1.00
105_S	108_A	0.612	1.00
101_V	181_A	0.612	1.00
23_D	180_A	0.612	1.00
29_G	47_P	0.605	1.00
153_T	156_V	0.604	1.00
84_G	87_R	0.604	1.00
18_E	172_A	0.603	1.00
5_V	20_L	0.599	1.00
154_G	157_T	0.598	1.00
119_R	122_L	0.590	1.00
101_V	182_L	0.588	1.00
59_A	63_C	0.587	1.00
2_D	62_G	0.583	1.00
132_L	141_I	0.578	1.00
65_G	98_D	0.575	1.00
56_V	60_V	0.574	1.00
108_A	129_D	0.574	1.00
35_A	38_D	0.573	1.00
60_V	97_V	0.572	1.00
48_V	55_D	0.570	1.00
151_A	158_V	0.565	1.00
123_A	126_A	0.565	1.00
154_G	160_D	0.565	1.00
81_D	125_K	0.562	1.00
153_T	159_A	0.559	1.00
111_P	118_L	0.553	1.00
20_L	25_H	0.553	1.00
78_D	124_A	0.552	1.00
125_K	128_A	0.552	1.00
72_S	81_D	0.550	1.00
65_G	101_V	0.550	1.00
28_R	59_A	0.548	1.00
30_M	48_V	0.548	1.00
146_S	168_S	0.545	1.00
50_A	59_A	0.544	1.00
34_P	38_D	0.543	1.00
124_A	128_A	0.542	1.00
155_R	158_V	0.541	1.00
150_D	172_A	0.538	1.00
69_A	144_P	0.538	1.00
37_T	40_I	0.538	1.00
145_G	167_G	0.534	1.00
18_E	43_L	0.531	1.00
71_G	81_D	0.530	1.00
25_H	65_G	0.529	1.00
120_S	124_A	0.528	1.00
120_S	123_A	0.528	1.00
138_A	186_A	0.528	1.00
4_L	59_A	0.528	1.00
164_P	201_V	0.527	1.00
153_T	160_D	0.523	1.00
153_T	158_V	0.522	1.00
121_Y	124_A	0.520	1.00
93_E	134_E	0.517	1.00
179_A	182_L	0.515	1.00
2_D	46_T	0.515	1.00
75_E	86_I	0.512	1.00
85_A	102_M	0.507	1.00
4_L	66_V	0.506	1.00
6_A	30_M	0.500	1.00

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
1i24A	4	1	100	0.235	Contact Map
4wkgA	5	0.9952	100	0.24	Contact Map
3slgA	4	0.9952	100	0.244	Contact Map
2bllA	2	0.9952	100	0.245	Contact Map
2x4gA	2	0.9667	100	0.248	Contact Map
1sb8A	2	1	100	0.249	Contact Map
2yy7A	2	0.9905	100	0.25	Contact Map
4pvcA	2	1	100	0.252	Contact Map
2c5aA	2	0.9905	100	0.252	Contact Map
3m2pA	2	0.9619	100	0.253	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.0081 seconds.