Q9HR79 - HALSA - GREMLIN Contacts

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Q9HR79 - Type II secretion system protein

UniProt:	Q9HR79	Sequences: MVTRLNAPVGAMAGDLFAGLDGGFDALQRRASRIVEVLRGTAVDVPPYDPQAHGPLVEFDGVADYEEVDRYWVNAPYAFVFIGFDAESDTHYYHVVEPHLDDFEQTVLDQLYDDIRDALIYDATTDPDDREAVLIAQMQRLLSEYSIDVTPNAFHRLFYYLHRTFEGFEKLDPVMQDPHIEDVSCDGYGLPLFVYHTDYTDIETNITYEQQELDSFVVRLAQQSGRHISIGDPVTETTLPDGSRAELALGEEVTPRGSAFTIRKYSEEPFTPATLVDYDTFSLDQMAYLWLAIESNKSLLFAGGTASGKTTSMNAVSMFVPPRAKILTIEDTRELALYHDNWLSSVTRGADGGGGDTITMYDLLRSALRHRPEYIIVGEVRGEEAMTLFQAMNTGHTTYSTMHADSVQTVINRLENDPINVPRAMIQSLDILCVQTLTHVGDERVRRSSVIAEIEGIDQRTGDLDYSTAFEWDPTRDDFEQRDSNVLDEIQDERGWSRSDLLRELRNRKRVLQYLVEQDVTDYRRFTALINEYYAQPERVVARVTDALDSDVAAAAPGVVE	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	561 (475)
Sequences:	3992 (2782)
Seq/√Len:	127.6

ECOLI - GSPE HOFB
HALSA - Q9HR79 Q9HQY3
SULSO - Q97VE6 Q97WB7 Q7LXX6

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
473_D	494_R	5.692	1.00
288_Y	316_V	4.401	1.00
479_F	490_I	4.186	1.00
217_V	260_F	3.977	1.00
406_S	409_T	3.856	1.00
291_L	431_I	3.757	1.00
259_A	325_K	3.685	1.00
441_G	511_V	3.567	1.00
324_A	374_Y	3.454	1.00
129_D	133_V	3.319	1.00
289_L	319_F	3.292	1.00
444_R	454_I	3.200	1.00
73_V	77_Y	3.004	1.00
327_L	367_A	2.884	1.00
492_D	499_S	2.833	1.00
501_L	515_L	2.789	1.00
473_D	490_I	2.741	1.00
476_R	487_L	2.722	1.00
233_P	356_D	2.684	1.00
440_V	464_L	2.666	1.00
441_G	446_R	2.632	1.00
433_C	469_A	2.620	1.00
329_I	363_L	2.586	1.00
300_L	400_S	2.519	1.00
90_T	116_R	2.498	1.00
490_I	493_E	2.492	1.00
302_A	402_M	2.491	1.00
255_P	333_R	2.480	1.00
380_V	388_L	2.466	1.00
490_I	494_R	2.461	1.00
292_A	316_V	2.425	1.00
243_S	266_S	2.390	1.00
252_E	343_L	2.382	1.00
192_L	213_L	2.381	1.00
464_L	509_K	2.362	1.00
472_W	480_E	2.359	1.00
285_Q	289_L	2.356	1.00
475_T	494_R	2.354	1.00
500_D	504_E	2.341	1.00
290_W	471_E	2.297	1.00
320_V	374_Y	2.233	1.00
408_Q	470_F	2.223	1.00
171_L	216_F	2.217	1.00
40_G	43_V	2.211	1.00
125_T	129_D	2.207	1.00
283_L	497_S	2.168	1.00
94_H	120_I	2.159	1.00
346_V	355_G	2.155	1.00
259_A	341_N	2.153	1.00
179_H	461_T	2.118	1.00
503_R	507_N	2.116	1.00
86_A	113_D	2.091	1.00
224_S	249_L	2.091	1.00
247_L	262_I	2.078	1.00
39_R	44_D	2.060	1.00
93_Y	107_V	2.052	1.00
120_I	125_T	2.016	1.00
251_E	260_F	1.987	1.00
483_D	486_V	1.978	1.00
204_T	207_T	1.953	1.00
282_S	286_M	1.940	1.00
406_S	488_D	1.934	1.00
411_I	429_L	1.921	1.00
75_A	79_F	1.921	1.00
502_L	506_R	1.907	1.00
41_T	123_A	1.900	1.00
201_D	517_E	1.897	1.00
284_D	469_A	1.896	1.00
121_Y	124_T	1.888	1.00
226_R	251_E	1.876	1.00
49_D	56_L	1.875	1.00
250_G	370_H	1.810	1.00
284_D	467_S	1.789	1.00
359_T	362_D	1.781	1.00
247_L	264_K	1.781	1.00
45_V	119_L	1.774	1.00
191_P	207_T	1.760	1.00
415_E	426_I	1.748	1.00
444_R	461_T	1.747	1.00
254_T	341_N	1.745	1.00
92_Y	118_A	1.734	1.00
107_V	115_I	1.730	1.00
281_F	284_D	1.719	1.00
478_D	482_R	1.709	1.00
321_P	326_I	1.689	1.00
505_L	515_L	1.687	1.00
95_V	117_D	1.685	1.00
85_D	92_Y	1.679	1.00
475_T	490_I	1.663	1.00
343_L	367_A	1.609	1.00
452_A	455_E	1.604	1.00
475_T	493_E	1.599	1.00
294_E	430_D	1.586	1.00
204_T	322_P	1.581	1.00
346_V	356_D	1.573	1.00
125_T	133_V	1.568	1.00
482_R	486_V	1.566	1.00
329_I	367_A	1.562	1.00
220_L	249_L	1.562	1.00
80_V	96_V	1.553	1.00
489_E	493_E	1.530	1.00
71_Y	76_P	1.528	1.00
486_V	489_E	1.528	1.00
470_F	496_W	1.514	1.00
497_S	503_R	1.507	1.00
293_I	319_F	1.506	1.00
101_D	105_Q	1.499	1.00
474_P	477_D	1.494	1.00
363_L	367_A	1.481	1.00
84_F	94_H	1.479	1.00
280_T	312_S	1.473	1.00
442_D	452_A	1.473	1.00
127_P	131_E	1.469	1.00
286_M	290_W	1.459	1.00
104_E	117_D	1.442	1.00
185_C	192_L	1.437	1.00
464_L	504_E	1.435	1.00
442_D	455_E	1.433	1.00
58_E	61_G	1.433	1.00
128_D	133_V	1.423	1.00
408_Q	487_L	1.423	1.00
283_L	287_A	1.421	1.00
265_Y	335_L	1.419	1.00
259_A	327_L	1.417	1.00
49_D	54_G	1.411	1.00
491_Q	495_G	1.398	1.00
284_D	500_D	1.396	1.00
233_P	358_I	1.389	1.00
284_D	287_A	1.388	1.00
193_F	204_T	1.386	1.00
442_D	445_V	1.380	1.00
201_D	439_H	1.356	1.00
445_V	452_A	1.352	1.00
393_N	425_M	1.347	1.00
361_Y	384_E	1.343	1.00
492_D	496_W	1.338	1.00
84_F	118_A	1.330	1.00
91_H	111_L	1.328	1.00
97_E	100_L	1.316	1.00
299_L	397_T	1.309	1.00
445_V	455_E	1.309	1.00
460_R	510_R	1.293	1.00
299_L	431_I	1.292	1.00
45_V	56_L	1.284	1.00
89_D	113_D	1.283	1.00
287_A	471_E	1.275	1.00
180_I	198_D	1.273	1.00
198_D	203_E	1.263	1.00
129_D	132_A	1.261	1.00
186_D	195_Y	1.258	1.00
46_P	56_L	1.251	1.00
80_V	126_D	1.250	1.00
380_V	400_S	1.242	1.00
291_L	469_A	1.232	1.00
275_L	315_A	1.230	1.00
443_E	446_R	1.229	1.00
320_V	399_Y	1.218	0.99
43_V	46_P	1.212	0.99
466_Y	501_L	1.194	0.99
284_D	433_C	1.185	0.99
196_H	205_N	1.184	0.99
245_A	264_K	1.181	0.99
94_H	118_A	1.171	0.99
128_D	131_E	1.161	0.99
58_E	124_T	1.160	0.99
476_R	491_Q	1.151	0.99
127_P	133_V	1.151	0.99
386_M	421_V	1.149	0.99
48_Y	51_Q	1.148	0.99
201_D	323_R	1.141	0.99
63_A	67_E	1.131	0.99
52_A	99_H	1.131	0.99
250_G	261_T	1.128	0.99
223_Q	239_L	1.124	0.99
70_R	86_A	1.116	0.99
300_L	380_V	1.115	0.99
138_M	141_L	1.113	0.99
504_E	509_K	1.109	0.99
274_T	277_D	1.108	0.99
432_L	470_F	1.107	0.99
408_Q	488_D	1.107	0.99
389_F	421_V	1.100	0.99
71_Y	107_V	1.098	0.99
329_I	345_S	1.095	0.99
80_V	122_D	1.093	0.99
488_D	492_D	1.089	0.99
301_F	433_C	1.088	0.99
276_V	285_Q	1.071	0.99
92_Y	116_R	1.070	0.99
347_T	356_D	1.069	0.99
239_L	247_L	1.068	0.99
171_L	220_L	1.064	0.99
305_T	396_H	1.063	0.99
412_N	484_S	1.063	0.99
278_Y	467_S	1.062	0.99
390_Q	416_N	1.062	0.99
179_H	198_D	1.061	0.99
210_Q	213_L	1.059	0.99
460_R	511_V	1.053	0.98
502_L	512_L	1.050	0.98
41_T	121_Y	1.048	0.98
357_T	362_D	1.044	0.98
281_F	503_R	1.040	0.98
166_E	169_E	1.038	0.98
290_W	294_E	1.038	0.98
429_L	432_L	1.037	0.98
275_L	289_L	1.036	0.98
129_D	134_L	1.029	0.98
305_T	372_P	1.028	0.98
312_S	433_C	1.026	0.98
504_E	507_N	1.024	0.98
244_R	267_E	1.022	0.98
227_H	355_G	1.022	0.98
33_R	39_R	1.019	0.98
441_G	447_R	1.018	0.98
280_T	288_Y	1.015	0.98
298_S	398_T	1.009	0.98
84_F	92_Y	1.004	0.98
364_L	387_T	1.003	0.98
137_Q	142_L	1.000	0.98
367_A	375_I	1.000	0.98
478_D	489_E	0.998	0.98
411_I	480_E	0.994	0.98
158_F	161_L	0.994	0.98
280_T	465_D	0.993	0.98
500_D	503_R	0.991	0.98
415_E	423_R	0.984	0.98
438_T	510_R	0.983	0.98
296_N	430_D	0.981	0.98
375_I	391_A	0.981	0.98
42_A	56_L	0.972	0.97
45_V	121_Y	0.966	0.97
138_M	142_L	0.964	0.97
296_N	406_S	0.961	0.97
41_T	45_V	0.960	0.97
128_D	132_A	0.959	0.97
503_R	506_R	0.958	0.97
327_L	343_L	0.958	0.97
426_I	429_L	0.957	0.97
276_V	289_L	0.956	0.97
250_G	366_S	0.955	0.97
72_W	75_A	0.954	0.97
408_Q	484_S	0.953	0.97
347_T	359_T	0.947	0.97
174_V	194_V	0.946	0.97
79_F	103_F	0.944	0.97
57_V	84_F	0.942	0.97
292_A	399_Y	0.941	0.97
174_V	183_V	0.930	0.97
125_T	128_D	0.929	0.97
501_L	504_E	0.928	0.97
379_E	403_H	0.926	0.97
245_A	266_S	0.924	0.96
70_R	76_P	0.923	0.96
302_A	404_A	0.923	0.96
288_Y	469_A	0.921	0.96
292_A	299_L	0.920	0.96
491_Q	496_W	0.919	0.96
259_A	370_H	0.917	0.96
470_F	487_L	0.917	0.96
280_T	467_S	0.913	0.96
321_P	339_H	0.911	0.96
476_R	490_I	0.909	0.96
103_F	107_V	0.909	0.96
390_Q	393_N	0.907	0.96
448_S	451_I	0.905	0.96
472_W	476_R	0.903	0.96
226_R	250_G	0.899	0.96
408_Q	496_W	0.898	0.96
178_P	203_E	0.897	0.96
367_A	377_V	0.896	0.96
43_V	47_P	0.895	0.96
107_V	111_L	0.894	0.96
219_R	223_Q	0.894	0.96
81_F	93_Y	0.893	0.96
224_S	239_L	0.893	0.96
153_A	156_R	0.891	0.96
226_R	260_F	0.889	0.96
287_A	290_W	0.883	0.95
155_H	159_Y	0.882	0.95
45_V	49_D	0.880	0.95
301_F	312_S	0.875	0.95
343_L	363_L	0.874	0.95
359_T	384_E	0.872	0.95
108_L	114_D	0.867	0.95
327_L	341_N	0.867	0.95
506_R	509_K	0.866	0.95
152_N	155_H	0.866	0.95
67_E	70_R	0.864	0.95
369_R	381_R	0.862	0.95
106_T	109_D	0.861	0.95
81_F	103_F	0.859	0.95
39_R	47_P	0.858	0.95
439_H	514_Y	0.857	0.95
71_Y	83_G	0.856	0.95
155_H	158_F	0.855	0.95
188_Y	193_F	0.854	0.95
402_M	410_V	0.854	0.95
380_V	386_M	0.853	0.95
512_L	516_V	0.853	0.95
191_P	338_Y	0.850	0.94
441_G	448_S	0.850	0.94
175_M	183_V	0.844	0.94
139_Q	142_L	0.844	0.94
452_A	459_Q	0.843	0.94
198_D	205_N	0.840	0.94
502_L	505_L	0.839	0.94
155_H	160_Y	0.838	0.94
46_P	50_P	0.838	0.94
68_V	132_A	0.837	0.94
96_V	125_T	0.835	0.94
175_M	247_L	0.834	0.94
111_L	114_D	0.831	0.94
90_T	114_D	0.829	0.94
168_F	172_D	0.827	0.94
238_T	246_E	0.823	0.93
305_T	394_T	0.822	0.93
281_F	507_N	0.819	0.93
410_V	432_L	0.818	0.93
40_G	47_P	0.817	0.93
39_R	43_V	0.816	0.93
142_L	145_Y	0.816	0.93
291_L	430_D	0.815	0.93
347_T	358_I	0.813	0.93
95_V	100_L	0.812	0.93
472_W	477_D	0.812	0.93
511_V	514_Y	0.811	0.93
153_A	157_L	0.809	0.93
42_A	46_P	0.809	0.93
137_Q	140_R	0.808	0.93
81_F	95_V	0.806	0.93
156_R	160_Y	0.803	0.93
365_R	384_E	0.799	0.92
310_T	335_L	0.799	0.92
181_E	261_T	0.798	0.92
299_L	430_D	0.795	0.92
404_A	407_V	0.792	0.92
170_K	174_V	0.792	0.92
104_E	108_L	0.789	0.92
270_F	274_T	0.786	0.92
505_L	512_L	0.784	0.92
334_E	403_H	0.783	0.92
34_I	44_D	0.780	0.91
125_T	131_E	0.779	0.91
82_I	125_T	0.779	0.91
325_K	370_H	0.778	0.91
369_R	403_H	0.776	0.91
83_G	86_A	0.776	0.91
291_L	299_L	0.776	0.91
105_Q	108_L	0.774	0.91
49_D	55_P	0.771	0.91
233_P	362_D	0.770	0.91
317_S	340_D	0.768	0.91
281_F	500_D	0.768	0.91
249_L	262_I	0.767	0.91
190_L	338_Y	0.767	0.91
66_E	69_D	0.767	0.91
218_V	228_I	0.767	0.91
378_G	403_H	0.766	0.91
79_F	106_T	0.757	0.90
191_P	204_T	0.756	0.90
281_F	504_E	0.756	0.90
447_R	451_I	0.754	0.90
81_F	107_V	0.751	0.90
50_P	53_H	0.749	0.90
368_L	391_A	0.748	0.90
318_M	321_P	0.747	0.90
208_Y	216_F	0.746	0.90
440_V	509_K	0.743	0.89
275_L	285_Q	0.741	0.89
95_V	103_F	0.740	0.89
34_I	37_V	0.740	0.89
189_G	256_R	0.739	0.89
221_A	258_S	0.737	0.89
431_I	469_A	0.737	0.89
263_R	403_H	0.737	0.89
362_D	366_S	0.736	0.89
369_R	379_E	0.736	0.89
96_V	122_D	0.735	0.89
358_I	363_L	0.735	0.89
314_N	337_L	0.733	0.89
460_R	513_Q	0.728	0.88
135_I	139_Q	0.728	0.88
304_G	436_T	0.727	0.88
199_Y	439_H	0.726	0.88
213_L	217_V	0.726	0.88
266_S	270_F	0.725	0.88
470_F	476_R	0.721	0.88
47_P	51_Q	0.720	0.88
73_V	76_P	0.719	0.88
87_E	92_Y	0.718	0.88
287_A	469_A	0.718	0.88
170_K	216_F	0.717	0.88
56_L	59_F	0.717	0.88
64_D	85_D	0.716	0.88
309_K	379_E	0.713	0.87
475_T	479_F	0.710	0.87
126_D	130_R	0.710	0.87
246_E	267_E	0.709	0.87
333_R	344_S	0.709	0.87
47_P	50_P	0.708	0.87
294_E	474_P	0.708	0.87
266_S	314_N	0.706	0.87
282_S	285_Q	0.704	0.87
453_E	457_I	0.704	0.87
168_F	219_R	0.703	0.87
263_R	379_E	0.702	0.87
64_D	67_E	0.702	0.87
325_K	341_N	0.702	0.87
267_E	335_L	0.700	0.86
243_S	268_E	0.698	0.86
455_E	459_Q	0.695	0.86
178_P	456_G	0.695	0.86
485_N	489_E	0.694	0.86
409_T	484_S	0.694	0.86
177_D	241_D	0.693	0.86
514_Y	517_E	0.693	0.86
163_R	368_L	0.693	0.86
316_V	329_I	0.693	0.86
389_F	425_M	0.692	0.86
95_V	104_E	0.692	0.86
37_V	41_T	0.691	0.86
283_L	286_M	0.691	0.86
498_R	501_L	0.690	0.86
42_A	58_E	0.690	0.86
484_S	488_D	0.690	0.86
88_S	116_R	0.688	0.85
470_F	491_Q	0.687	0.85
369_R	413_R	0.686	0.85
329_I	387_T	0.686	0.85
487_L	490_I	0.685	0.85
88_S	113_D	0.685	0.85
334_E	379_E	0.684	0.85
71_Y	81_F	0.683	0.85
45_V	54_G	0.683	0.85
45_V	52_A	0.683	0.85
252_E	367_A	0.683	0.85
56_L	121_Y	0.682	0.85
154_F	158_F	0.679	0.85
305_T	381_R	0.678	0.85
298_S	392_M	0.678	0.85
298_S	390_Q	0.677	0.85
67_E	82_I	0.676	0.84
452_A	468_T	0.676	0.84
475_T	478_D	0.675	0.84
320_V	324_A	0.675	0.84
320_V	326_I	0.674	0.84
367_A	477_D	0.673	0.84
220_L	260_F	0.672	0.84
305_T	369_R	0.671	0.84
168_F	171_L	0.670	0.84
479_F	486_V	0.669	0.84
236_E	250_G	0.668	0.84
274_T	319_F	0.667	0.84
310_T	337_L	0.667	0.84
42_A	121_Y	0.667	0.84
222_Q	228_I	0.666	0.84
283_L	503_R	0.664	0.83
82_I	128_D	0.663	0.83
329_I	343_L	0.661	0.83
263_R	334_E	0.658	0.83
474_P	489_E	0.658	0.83
49_D	119_L	0.656	0.83
186_D	231_G	0.655	0.83
126_D	129_D	0.652	0.82
309_K	403_H	0.652	0.82
331_D	344_S	0.651	0.82
356_D	362_D	0.651	0.82
130_R	478_D	0.650	0.82
487_L	491_Q	0.650	0.82
393_N	428_S	0.647	0.82
299_L	433_C	0.647	0.82
341_N	370_H	0.647	0.82
100_L	103_F	0.647	0.82
220_L	262_I	0.646	0.82
510_R	514_Y	0.646	0.82
215_S	222_Q	0.646	0.82
310_T	314_N	0.645	0.82
175_M	239_L	0.645	0.82
153_A	160_Y	0.644	0.81
67_E	86_A	0.644	0.81
298_S	429_L	0.642	0.81
416_N	481_Q	0.642	0.81
225_G	292_A	0.642	0.81
94_H	125_T	0.640	0.81
372_P	396_H	0.639	0.81
471_E	494_R	0.638	0.81
296_N	311_T	0.638	0.81
312_S	435_Q	0.638	0.81
170_K	208_Y	0.637	0.81
414_L	426_I	0.633	0.80
96_V	99_H	0.633	0.80
375_I	495_G	0.632	0.80
162_H	168_F	0.631	0.80
91_H	115_I	0.629	0.80
87_E	90_T	0.628	0.80
313_M	376_I	0.628	0.80
383_E	420_N	0.628	0.80
291_L	471_E	0.626	0.80
130_R	133_V	0.626	0.80
113_D	117_D	0.625	0.80
33_R	44_D	0.625	0.80
337_L	340_D	0.625	0.80
172_D	176_Q	0.624	0.79
212_E	216_F	0.623	0.79
154_F	157_L	0.623	0.79
343_L	358_I	0.622	0.79
127_P	132_A	0.622	0.79
76_P	81_F	0.621	0.79
261_T	325_K	0.619	0.79
146_S	150_T	0.618	0.79
369_R	378_G	0.616	0.79
295_S	405_D	0.616	0.79
392_M	428_S	0.615	0.78
89_D	92_Y	0.614	0.78
284_D	497_S	0.613	0.78
302_A	410_V	0.613	0.78
40_G	46_P	0.612	0.78
474_P	485_N	0.612	0.78
381_R	413_R	0.611	0.78
381_R	403_H	0.611	0.78
438_T	501_L	0.610	0.78
182_D	369_R	0.610	0.78
288_Y	299_L	0.610	0.78
246_E	335_L	0.609	0.78
466_Y	504_E	0.609	0.78
76_P	133_V	0.608	0.78
122_D	126_D	0.607	0.78
261_T	370_H	0.607	0.78
256_R	336_A	0.607	0.78
430_D	477_D	0.607	0.78
150_T	155_H	0.606	0.77
438_T	464_L	0.606	0.77
234_V	385_A	0.606	0.77
479_F	487_L	0.606	0.77
79_F	100_L	0.602	0.77
321_P	324_A	0.601	0.77
44_D	48_Y	0.600	0.77
44_D	47_P	0.600	0.77
389_F	393_N	0.599	0.77
187_G	414_L	0.599	0.77
373_E	430_D	0.599	0.77
134_L	138_M	0.599	0.77
75_A	110_Q	0.597	0.76
492_D	495_G	0.597	0.76
102_D	465_D	0.596	0.76
370_H	390_Q	0.596	0.76
409_T	412_N	0.593	0.76
136_A	139_Q	0.591	0.76
410_V	425_M	0.590	0.76
91_H	113_D	0.590	0.76
356_D	359_T	0.589	0.75
371_R	463_D	0.588	0.75
305_T	403_H	0.588	0.75
327_L	335_L	0.586	0.75
67_E	83_G	0.586	0.75
169_E	355_G	0.585	0.75
402_M	414_L	0.585	0.75
404_A	410_V	0.585	0.75
438_T	515_L	0.584	0.75
417_D	467_S	0.583	0.75
57_V	120_I	0.583	0.75
438_T	466_Y	0.583	0.75
157_L	160_Y	0.582	0.75
182_D	403_H	0.582	0.75
203_E	456_G	0.582	0.75
136_A	140_R	0.579	0.74
255_P	336_A	0.577	0.74
157_L	161_L	0.577	0.74
240_P	247_L	0.577	0.74
301_F	313_M	0.577	0.74
185_C	213_L	0.577	0.74
128_D	134_L	0.576	0.74
240_P	244_R	0.576	0.74
298_S	389_F	0.576	0.74
305_T	379_E	0.576	0.74
452_A	463_D	0.575	0.74
298_S	368_L	0.575	0.74
366_S	370_H	0.575	0.74
187_G	370_H	0.573	0.73
378_G	381_R	0.572	0.73
361_Y	366_S	0.571	0.73
52_A	119_L	0.571	0.73
246_E	328_T	0.571	0.73
236_E	369_R	0.570	0.73
409_T	425_M	0.568	0.73
57_V	118_A	0.567	0.73
192_L	216_F	0.567	0.73
76_P	83_G	0.567	0.73
63_A	68_V	0.566	0.73
139_Q	143_S	0.565	0.72
127_P	130_R	0.563	0.72
125_T	132_A	0.563	0.72
468_T	496_W	0.563	0.72
298_S	431_I	0.563	0.72
153_A	161_L	0.561	0.72
100_L	104_E	0.561	0.72
269_P	274_T	0.560	0.72
87_E	116_R	0.557	0.71
184_S	332_T	0.557	0.71
33_R	36_E	0.557	0.71
35_V	43_V	0.555	0.71
93_Y	117_D	0.555	0.71
302_A	434_V	0.554	0.71
494_R	497_S	0.554	0.71
415_E	495_G	0.553	0.71
155_H	161_L	0.553	0.71
499_S	503_R	0.553	0.71
252_E	366_S	0.553	0.71
311_T	335_L	0.552	0.71
390_Q	431_I	0.552	0.71
125_T	130_R	0.551	0.71
381_R	396_H	0.550	0.70
271_T	274_T	0.549	0.70
509_K	515_L	0.547	0.70
298_S	388_L	0.547	0.70
423_R	480_E	0.546	0.70
459_Q	463_D	0.545	0.70
239_L	249_L	0.545	0.70
192_L	217_V	0.545	0.70
151_P	157_L	0.544	0.70
102_D	106_T	0.543	0.69
186_D	230_I	0.543	0.69
416_N	425_M	0.543	0.69
248_A	382_G	0.542	0.69
233_P	357_T	0.542	0.69
130_R	134_L	0.541	0.69
436_T	463_D	0.541	0.69
156_R	159_Y	0.540	0.69
266_S	335_L	0.540	0.69
499_S	502_L	0.539	0.69
238_T	390_Q	0.538	0.69
171_L	196_H	0.536	0.68
236_E	378_G	0.536	0.68
76_P	363_L	0.535	0.68
195_Y	370_H	0.534	0.68
222_Q	259_A	0.534	0.68
135_I	138_M	0.534	0.68
369_R	401_T	0.534	0.68
46_P	49_D	0.533	0.68
290_W	293_I	0.533	0.68
369_R	396_H	0.532	0.68
252_E	370_H	0.531	0.68
95_V	101_D	0.530	0.68
184_S	463_D	0.529	0.67
96_V	120_I	0.529	0.67
359_T	480_E	0.529	0.67
238_T	374_Y	0.528	0.67
263_R	369_R	0.528	0.67
486_V	490_I	0.528	0.67
60_D	124_T	0.527	0.67
280_T	284_D	0.526	0.67
205_N	244_R	0.526	0.67
477_D	481_Q	0.525	0.67
376_I	424_A	0.525	0.67
65_Y	69_D	0.525	0.67
440_V	444_R	0.525	0.67
510_R	515_L	0.525	0.67
171_L	310_T	0.525	0.67
382_G	385_A	0.524	0.67
302_A	392_M	0.524	0.67
292_A	295_S	0.524	0.67
188_Y	259_A	0.524	0.67
102_D	105_Q	0.523	0.67
49_D	52_A	0.523	0.67
334_E	369_R	0.523	0.67
156_R	161_L	0.523	0.67
442_D	459_Q	0.522	0.66
131_E	134_L	0.522	0.66
314_N	340_D	0.522	0.66
54_G	95_V	0.521	0.66
145_Y	456_G	0.520	0.66
276_V	282_S	0.518	0.66
124_T	127_P	0.518	0.66
100_L	106_T	0.518	0.66
364_L	367_A	0.517	0.66
134_L	137_Q	0.516	0.66
129_D	138_M	0.515	0.65
267_E	270_F	0.515	0.65
34_I	39_R	0.515	0.65
133_V	138_M	0.515	0.65
498_R	502_L	0.514	0.65
129_D	135_I	0.514	0.65
162_H	215_S	0.514	0.65
95_V	99_H	0.514	0.65
140_R	143_S	0.513	0.65
298_S	430_D	0.512	0.65
193_F	207_T	0.512	0.65
288_Y	433_C	0.511	0.65
232_D	356_D	0.510	0.65
39_R	56_L	0.510	0.65
455_E	462_G	0.509	0.65
56_L	124_T	0.509	0.65
263_R	309_K	0.509	0.65
226_R	331_D	0.508	0.64
182_D	379_E	0.508	0.64
194_V	375_I	0.508	0.64
35_V	50_P	0.507	0.64
108_L	115_I	0.507	0.64
52_A	95_V	0.506	0.64
446_R	511_V	0.505	0.64
186_D	370_H	0.505	0.64
182_D	263_R	0.504	0.64
299_L	470_F	0.503	0.64
160_Y	163_R	0.503	0.64
86_A	89_D	0.502	0.63
239_L	411_I	0.502	0.63
37_V	421_V	0.501	0.63
399_Y	427_Q	0.501	0.63
401_T	411_I	0.501	0.63
292_A	498_R	0.501	0.63
270_F	310_T	0.500	0.63

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
4phtA	1	0.7291	100	0.449	Contact Map
2oap1	3	0.8966	100	0.486	Contact Map
4ksrA	3	0.6471	100	0.525	Contact Map
4ihqA	3	0.877	100	0.538	Contact Map
1p9rA	1	0.6239	100	0.544	Contact Map
2ewvA	3	0.5829	100	0.652	Contact Map
3jvvA	3	0.5615	100	0.659	Contact Map
2gzaA	3	0.5383	100	0.738	Contact Map
2eyuA	1	0.4064	100	0.753	Contact Map
4bloA	4	0.451	100	0.776	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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