GREMLIN Database
PURL - Phosphoribosylformylglycinamidine synthase subunit PurL
UniProt: Q9HR49 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 700 (684)
Sequences: 3177 (1599)
Seq/√Len: 61.2

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
337_N349_D4.7911.00
614_L626_V4.6631.00
277_R332_E4.6051.00
548_L554_L4.5381.00
90_Y141_D4.4821.00
622_A666_A4.0641.00
464_L469_A3.9661.00
605_I643_V3.6311.00
346_T349_D3.5861.00
613_T643_V3.5411.00
279_T282_A3.5211.00
277_R341_E3.3741.00
317_R321_T3.1981.00
671_T682_T3.1891.00
265_S330_I3.1511.00
198_A326_G3.1431.00
555_V662_R3.0801.00
314_D318_E2.9401.00
545_G549_A2.9391.00
314_D317_R2.8911.00
388_V394_T2.8421.00
341_E346_T2.8351.00
647_R650_D2.7721.00
451_A454_Y2.7591.00
555_V652_L2.6941.00
554_L624_A2.6861.00
380_A383_T2.6581.00
207_A258_A2.6531.00
624_A672_L2.6481.00
155_T400_V2.6431.00
391_A568_V2.6341.00
625_T673_S2.6321.00
593_A652_L2.6301.00
544_P594_A2.6201.00
281_D343_D2.5111.00
193_V308_V2.4711.00
555_V653_Q2.4701.00
601_A617_M2.4561.00
492_F517_L2.4481.00
455_A639_P2.4471.00
450_Y501_D2.4431.00
312_D315_A2.4311.00
555_V660_V2.4201.00
615_A672_L2.3811.00
385_I611_A2.3791.00
625_T665_S2.3441.00
383_T387_A2.3301.00
151_V421_A2.3281.00
433_T540_Q2.3151.00
284_H328_S2.3091.00
386_D691_H2.2871.00
191_K329_V2.2751.00
315_A318_E2.2751.00
499_L532_L2.2641.00
414_Q545_G2.2561.00
460_N532_L2.2421.00
460_N534_V2.2311.00
548_L624_A2.2161.00
146_I238_I2.2081.00
66_R177_E2.1771.00
589_A656_L2.1761.00
601_A645_E2.1641.00
292_A342_F2.1421.00
644_V652_L2.1161.00
557_V644_V2.1061.00
590_V644_V2.0791.00
114_L171_C2.0631.00
418_E467_A2.0481.00
656_L660_V2.0221.00
480_G495_M2.0211.00
285_Q295_I2.0041.00
277_R339_V1.9841.00
72_Q176_T1.9801.00
74_V434_V1.9571.00
7_D38_R1.9541.00
445_T495_M1.9371.00
317_R327_C1.9361.00
382_G386_D1.9341.00
592_E596_R1.9341.00
419_D603_H1.9291.00
112_I423_L1.9231.00
569_Y631_L1.9201.00
553_D645_E1.9151.00
614_L643_V1.9141.00
11_V27_F1.9121.00
444_W455_A1.9031.00
168_N531_T1.9021.00
55_V73_L1.8991.00
553_D666_A1.8901.00
494_A497_A1.8871.00
339_V346_T1.8861.00
610_L643_V1.8801.00
431_G541_H1.8591.00
243_T322_R1.8471.00
465_A591_R1.8471.00
590_V599_T1.8461.00
584_A588_D1.8351.00
618_V624_A1.8331.00
42_S363_D1.8311.00
614_L624_A1.8291.00
398_E693_G1.8291.00
617_M645_E1.8281.00
279_T341_E1.8191.00
683_R687_T1.8131.00
367_T487_D1.8131.00
101_V146_I1.8051.00
366_S493_E1.8051.00
689_R693_G1.7981.00
600_L647_R1.7730.99
313_V329_V1.7600.99
205_G208_S1.7530.99
554_L645_E1.7490.99
553_D600_L1.7480.99
46_A497_A1.7470.99
281_D342_F1.7400.99
191_K332_E1.7310.99
594_A599_T1.7220.99
191_K313_V1.7200.99
615_A619_T1.7170.99
555_V644_V1.7040.99
382_G687_T1.7020.99
603_H616_E1.6930.99
458_V639_P1.6870.99
9_E13_A1.6870.99
542_P595_T1.6770.99
385_I615_A1.6710.99
683_R688_I1.6620.99
270_A356_A1.6590.99
160_G527_A1.6580.99
101_V171_C1.6550.99
122_D159_D1.6450.99
431_G539_D1.6430.99
386_D687_T1.6250.99
542_P597_A1.6210.99
191_K308_V1.6110.99
673_S682_T1.6030.99
411_R424_A1.5990.99
448_Q579_F1.5860.99
600_L645_E1.5740.99
548_L617_M1.5740.99
625_T667_T1.5740.99
488_V525_P1.5720.99
556_L605_I1.5650.99
684_D687_T1.5580.99
116_D139_I1.5490.99
368_V490_G1.5300.98
621_D689_R1.5280.98
64_V75_T1.5240.98
329_V332_E1.5100.98
154_A397_N1.5030.98
646_T652_L1.4960.98
475_V509_P1.4910.98
209_F214_L1.4890.98
53_A470_E1.4810.98
390_S691_H1.4810.98
393_N568_V1.4810.98
598_D650_D1.4730.98
386_D683_R1.4700.98
385_I612_V1.4610.98
611_A674_V1.4530.98
295_I342_F1.4530.98
599_T644_V1.4500.98
401_Y417_G1.4420.98
15_L351_P1.4300.98
394_T612_V1.4290.98
551_D668_T1.4240.97
191_K310_P1.4180.97
539_D542_P1.4110.97
382_G683_R1.4090.97
599_T602_V1.4050.97
336_G339_V1.4010.97
453_A491_G1.3960.97
660_V663_L1.3890.97
447_C579_F1.3880.97
110_Y239_E1.3850.97
247_R315_A1.3840.97
472_L475_V1.3810.97
4_G362_T1.3790.97
368_V372_P1.3790.97
386_D688_I1.3780.97
448_Q578_Q1.3760.97
589_A655_A1.3750.97
70_T432_T1.3750.97
339_V349_D1.3710.97
193_V317_R1.3640.97
500_A504_R1.3600.97
409_G412_T1.3600.97
690_D694_V1.3600.97
391_A572_A1.3590.97
168_N438_A1.3580.97
66_R71_D1.3570.97
25_A293_M1.3410.96
398_E402_R1.3400.96
256_L264_A1.3380.96
390_S694_V1.3380.96
619_T692_R1.3360.96
115_A436_L1.3350.96
555_V646_T1.3340.96
86_Y214_L1.3320.96
618_V672_L1.3300.96
424_A540_Q1.3250.96
444_W639_P1.3230.96
422_G543_V1.3210.96
450_Y494_A1.3080.96
188_P335_T1.3070.96
194_L256_L1.3030.96
10_R13_A1.3030.96
318_E321_T1.2990.96
48_D56_V1.2960.96
501_D505_A1.2940.96
459_E606_S1.2920.96
396_S693_G1.2850.95
563_G638_C1.2840.95
466_A602_V1.2820.95
481_G491_G1.2800.95
470_E595_T1.2790.95
73_L177_E1.2760.95
244_L316_V1.2740.95
71_D177_E1.2730.95
51_S65_V1.2700.95
550_G553_D1.2670.95
308_V313_V1.2670.95
378_D631_L1.2580.95
605_I613_T1.2570.95
604_D616_E1.2540.95
593_A599_T1.2430.94
201_R294_E1.2390.94
292_A347_V1.2380.94
364_Q484_E1.2300.94
562_D636_S1.2260.94
190_N251_V1.2160.94
192_L276_A1.2150.94
463_N604_D1.2140.94
65_V473_A1.2100.94
249_L312_D1.2070.94
352_A356_A1.2060.94
420_A435_A1.2040.93
379_P384_A1.2010.93
435_A464_L1.1980.93
195_V320_A1.1970.93
192_L307_E1.1960.93
251_V309_A1.1950.93
550_G600_L1.1900.93
611_A615_A1.1880.93
309_A312_D1.1870.93
548_L645_E1.1870.93
190_N333_V1.1830.93
279_T343_D1.1800.93
625_T675_T1.1630.92
125_D162_T1.1620.92
27_F354_V1.1600.92
120_F132_L1.1600.92
437_S460_N1.1480.92
168_N477_C1.1480.92
176_T179_R1.1410.91
614_L663_L1.1390.91
170_A533_A1.1380.91
598_D651_A1.1380.91
560_H638_C1.1370.91
389_L615_A1.1310.91
461_A508_T1.1290.91
399_W403_Q1.1290.91
459_E604_D1.1280.91
607_D616_E1.1270.91
461_A587_V1.1250.91
78_V438_A1.1250.91
78_V531_T1.1220.91
340_C348_V1.1200.91
612_V616_E1.1180.91
549_A645_E1.1160.91
115_A170_A1.1150.91
158_H446_A1.1150.91
66_R69_G1.1150.91
475_V533_A1.1040.90
130_Y134_G1.1020.90
490_G494_A1.1010.90
560_H563_G1.0980.90
498_G502_G1.0970.90
5_D9_E1.0960.90
85_S135_V1.0940.90
560_H641_R1.0930.90
161_Y440_A1.0880.89
435_A469_A1.0870.89
86_Y209_F1.0840.89
158_H443_G1.0790.89
448_Q451_A1.0790.89
433_T543_V1.0770.89
277_R336_G1.0750.89
652_L656_L1.0740.89
26_L350_A1.0720.89
627_T675_T1.0720.89
43_L47_F1.0720.89
653_Q660_V1.0700.89
414_Q422_G1.0690.89
122_D162_T1.0650.88
46_A500_A1.0630.88
445_T456_T1.0630.88
557_V586_G1.0630.88
268_M307_E1.0620.88
392_P395_A1.0610.88
114_L146_I1.0590.88
193_V329_V1.0560.88
133_D137_E1.0550.88
450_Y497_A1.0530.88
464_L475_V1.0530.88
554_L626_V1.0520.88
557_V656_L1.0520.88
411_R426_H1.0500.88
548_L666_A1.0500.88
73_L175_V1.0480.88
287_E290_M1.0470.88
216_E522_A1.0460.87
283_V295_I1.0440.87
251_V312_D1.0440.87
387_A573_L1.0430.87
596_R651_A1.0420.87
44_L47_F1.0410.87
437_S464_L1.0400.87
687_T691_H1.0400.87
477_C531_T1.0380.87
667_T670_G1.0380.87
447_C577_D1.0320.87
441_N459_E1.0270.87
296_L340_C1.0220.86
546_S620_A1.0170.86
134_G137_E1.0170.86
75_T109_A1.0150.86
552_G666_A1.0140.86
265_S338_Y1.0100.86
606_S616_E1.0090.86
651_A655_A1.0050.85
101_V148_V1.0040.85
9_E12_V1.0030.85
605_I610_L1.0010.85
501_D504_R1.0010.85
492_F496_V0.9970.85
367_T486_P0.9920.85
308_V316_V0.9920.85
187_S309_A0.9920.85
538_R595_T0.9910.84
670_G685_A0.9910.84
651_A654_A0.9890.84
488_V492_F0.9890.84
449_P487_D0.9880.84
58_P185_A0.9790.84
353_T357_D0.9770.84
691_H694_V0.9750.84
413_V424_A0.9740.83
554_L614_L0.9710.83
53_A472_L0.9700.83
622_A668_T0.9680.83
389_L394_T0.9680.83
686_A689_R0.9670.83
425_L432_T0.9650.83
22_A348_V0.9650.83
243_T319_V0.9630.83
388_V612_V0.9610.83
209_F225_A0.9610.83
61_D106_S0.9550.82
86_Y165_P0.9550.82
377_P380_A0.9500.82
249_L315_A0.9490.82
140_S169_V0.9480.82
280_L342_F0.9470.82
354_V358_G0.9470.82
319_V322_R0.9470.82
554_L557_V0.9470.82
646_T649_A0.9460.82
414_Q418_E0.9450.82
350_A356_A0.9450.82
137_E141_D0.9420.81
201_R287_E0.9420.81
187_S251_V0.9400.81
426_H430_D0.9370.81
688_I692_R0.9360.81
281_D344_G0.9350.81
470_E538_R0.9350.81
590_V594_A0.9340.81
470_E591_R0.9340.81
406_H416_P0.9330.81
662_R665_S0.9330.81
687_T690_D0.9310.81
131_L165_P0.9300.81
46_A504_R0.9300.81
188_P274_L0.9290.80
8_R12_V0.9270.80
627_T678_D0.9220.80
619_T689_R0.9180.80
624_A664_G0.9170.80
132_L400_V0.9140.79
187_S190_N0.9120.79
43_L489_Y0.9110.79
557_V590_V0.9100.79
550_G666_A0.9060.79
628_V633_A0.9050.79
109_A172_V0.9050.79
244_L306_Y0.9050.79
193_V327_C0.9050.79
553_D648_D0.9040.79
653_Q662_R0.9040.79
654_A657_D0.9040.79
593_A598_D0.9040.79
101_V114_L0.8990.78
459_E616_E0.8970.78
457_A499_L0.8960.78
646_T650_D0.8910.78
46_A496_V0.8900.78
386_D390_S0.8890.77
445_T452_G0.8870.77
550_G647_R0.8870.77
463_N616_E0.8870.77
110_Y242_E0.8850.77
596_R655_A0.8840.77
285_Q290_M0.8830.77
593_A644_V0.8800.77
273_E353_T0.8790.77
468_G538_R0.8770.76
368_V494_A0.8770.76
548_L622_A0.8740.76
90_Y229_G0.8730.76
128_A162_T0.8710.76
341_E344_G0.8710.76
554_L663_L0.8700.76
306_Y316_V0.8700.76
318_E322_R0.8700.76
61_D254_R0.8680.76
58_P252_A0.8660.76
53_A65_V0.8640.75
549_A552_G0.8630.75
442_P531_T0.8630.75
407_E415_R0.8630.75
121_G162_T0.8620.75
321_T327_C0.8590.75
293_M297_L0.8590.75
591_R595_T0.8580.75
193_V313_V0.8580.75
598_D655_A0.8560.75
152_A437_S0.8550.75
270_A353_T0.8540.75
453_A495_M0.8530.74
365_P486_P0.8530.74
567_S580_P0.8510.74
612_V615_A0.8480.74
112_I434_V0.8470.74
556_L643_V0.8470.74
682_T687_T0.8460.74
618_V645_E0.8450.74
618_V685_A0.8420.73
568_V571_Q0.8400.73
643_V663_L0.8370.73
458_V462_T0.8360.73
685_A689_R0.8350.73
123_F132_L0.8350.73
3_L11_V0.8350.73
150_T421_A0.8340.73
414_Q543_V0.8340.73
477_C499_L0.8330.73
589_A593_A0.8330.73
507_D584_A0.8310.73
315_A319_V0.8310.73
48_D54_V0.8300.72
115_A152_A0.8300.72
172_V535_V0.8280.72
485_D520_D0.8280.72
43_L492_F0.8280.72
557_V589_A0.8280.72
603_H606_S0.8280.72
72_Q174_L0.8270.72
459_E463_N0.8250.72
651_A675_T0.8250.72
463_N603_H0.8250.72
558_G562_D0.8220.72
627_T630_G0.8220.72
419_D606_S0.8200.72
592_E655_A0.8190.71
378_D569_Y0.8160.71
448_Q494_A0.8150.71
381_L635_F0.8150.71
689_R692_R0.8130.71
67_V425_L0.8120.71
24_A61_D0.8110.71
593_A655_A0.8100.71
465_A594_A0.8090.70
378_D381_L0.8090.70
464_L534_V0.8070.70
461_A534_V0.8070.70
70_T176_T0.8070.70
310_P332_E0.8040.70
413_V540_Q0.8030.70
474_A510_V0.8010.70
117_A154_A0.7960.69
39_S489_Y0.7950.69
459_E603_H0.7950.69
537_Y543_V0.7940.69
282_A343_D0.7920.69
335_T386_D0.7890.69
586_G641_R0.7890.69
413_V433_T0.7870.68
589_A592_E0.7870.68
39_S364_Q0.7870.68
189_G332_E0.7870.68
381_L385_I0.7860.68
670_G686_A0.7850.68
112_I425_L0.7850.68
388_V611_A0.7840.68
547_G620_A0.7820.68
240_A320_A0.7810.68
209_F489_Y0.7800.68
465_A587_V0.7790.68
338_Y350_A0.7760.67
146_I171_C0.7760.67
588_D592_E0.7740.67
544_P602_V0.7740.67
463_N606_S0.7730.67
48_D507_D0.7720.67
618_V674_V0.7710.67
669_D681_V0.7710.67
604_D607_D0.7700.67
653_Q656_L0.7700.67
269_V276_A0.7690.67
406_H415_R0.7670.66
160_G446_A0.7640.66
559_G659_P0.7630.66
122_D571_Q0.7620.66
473_A508_T0.7620.66
508_T534_V0.7610.66
450_Y453_A0.7600.66
410_A426_H0.7600.66
544_P599_T0.7590.66
156_Q607_D0.7590.66
263_G512_G0.7550.65
686_A690_D0.7540.65
648_D651_A0.7540.65
419_D463_N0.7530.65
551_D622_A0.7500.65
439_G463_N0.7420.64
600_L650_D0.7420.64
683_R686_A0.7410.64
431_G540_Q0.7400.64
685_A688_I0.7400.64
105_L238_I0.7400.64
589_A652_L0.7380.63
43_L46_A0.7380.63
172_V436_L0.7360.63
54_V58_P0.7350.63
141_D145_A0.7340.63
53_A475_V0.7330.63
561_A638_C0.7320.63
283_V330_I0.7310.63
90_Y140_S0.7310.63
192_L278_I0.7310.63
179_R246_D0.7290.62
74_V172_V0.7270.62
549_A622_A0.7250.62
593_A597_A0.7250.62
454_Y501_D0.7250.62
240_A319_V0.7250.62
55_V64_V0.7240.62
624_A666_A0.7240.62
420_A543_V0.7240.62
435_A537_Y0.7230.62
492_F498_G0.7230.62
353_T358_G0.7220.62
622_A667_T0.7210.62
77_G169_V0.7210.62
670_G684_D0.7210.62
563_G581_A0.7200.61
553_D601_A0.7190.61
98_G142_Y0.7190.61
611_A635_F0.7190.61
170_A436_L0.7180.61
6_S363_D0.7160.61
59_G181_V0.7150.61
451_A581_A0.7150.61
223_R287_E0.7120.61
437_S467_A0.7080.60
485_D488_V0.7080.60
186_K190_N0.7080.60
652_L662_R0.7080.60
342_F347_V0.7070.60
122_D128_A0.7070.60
229_G286_R0.7050.60
652_L658_V0.7050.60
591_R594_A0.7030.60
313_V317_R0.7030.60
585_A651_A0.7030.60
252_A274_L0.7030.60
353_T356_A0.7030.60
489_Y496_V0.7030.60
83_H210_A0.7020.60
87_V209_F0.7000.59
465_A640_G0.7000.59
538_R542_P0.7000.59
258_A261_L0.7000.59
553_D622_A0.7000.59
67_V74_V0.6990.59
643_V647_R0.6990.59
65_V74_V0.6980.59
384_A388_V0.6980.59
88_D91_D0.6970.59
85_S134_G0.6970.59
384_A573_L0.6970.59
67_V434_V0.6950.59
256_L305_C0.6940.59
119_Y154_A0.6940.59
61_D77_G0.6930.59
266_S338_Y0.6930.59
437_S533_A0.6930.59
440_A445_T0.6920.58
215_A218_A0.6900.58
586_G658_V0.6890.58
286_R300_S0.6890.58
37_Y40_S0.6890.58
320_A327_C0.6870.58
337_N351_P0.6870.58
385_I683_R0.6850.58
41_R361_A0.6840.58
73_L180_L0.6840.58
398_E689_R0.6840.58
48_D51_S0.6830.57
676_V681_V0.6820.57
382_G682_T0.6820.57
161_Y529_T0.6820.57
677_D681_V0.6810.57
423_L434_V0.6810.57
554_L605_I0.6790.57
369_P487_D0.6790.57
181_V184_A0.6780.57
495_M532_L0.6780.57
654_A665_S0.6770.57
105_L304_M0.6770.57
90_Y231_P0.6760.57
76_V533_A0.6760.57
553_D647_R0.6760.57
307_E333_V0.6750.57
472_L588_D0.6750.57
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653_Q657_D0.6730.56
646_T655_A0.6720.56
337_N350_A0.6720.56
320_A325_L0.6710.56
90_Y145_A0.6700.56
269_V333_V0.6700.56
471_P474_A0.6700.56
441_N607_D0.6680.56
110_Y409_G0.6670.56
65_V425_L0.6670.56
112_I174_L0.6660.56
37_Y80_S0.6660.56
118_L139_I0.6660.56
159_D574_G0.6650.55
200_G286_R0.6650.55
464_L467_A0.6650.55
561_A583_D0.6650.55
554_L666_A0.6640.55
194_L265_S0.6630.55
490_G493_E0.6620.55
280_L340_C0.6590.55
249_L319_V0.6580.55
608_G637_E0.6580.55
461_A474_A0.6570.55
170_A438_A0.6560.54
376_R379_P0.6530.54
29_N208_S0.6530.54
64_V175_V0.6530.54
121_G158_H0.6530.54
54_V57_G0.6520.54
555_V658_V0.6520.54
318_E625_T0.6520.54
441_N604_D0.6510.54
41_R45_S0.6510.54
482_N485_D0.6500.54
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183_A252_A0.6420.53
590_V656_L0.6420.53
270_A357_D0.6410.53
563_G639_P0.6400.53
447_C565_G0.6400.53
603_H607_D0.6390.52
492_F495_M0.6390.52
334_T339_V0.6390.52
29_N32_S0.6380.52
10_R360_P0.6370.52
554_L646_T0.6370.52
457_A502_G0.6350.52
615_A624_A0.6350.52
285_Q342_F0.6340.52
467_A544_P0.6340.52
199_T285_Q0.6340.52
420_A467_A0.6340.52
652_L655_A0.6320.52
378_D384_A0.6320.52
488_V491_G0.6320.52
296_L338_Y0.6310.52
29_N205_G0.6310.52
275_G336_G0.6300.51
36_A39_S0.6300.51
633_A661_V0.6300.51
560_H636_S0.6300.51
212_E222_D0.6290.51
585_A589_A0.6290.51
673_S684_D0.6290.51
372_P375_D0.6280.51
585_A599_T0.6280.51
598_D648_D0.6280.51
570_L631_L0.6270.51
148_V409_G0.6270.51
680_T687_T0.6270.51
123_F392_P0.6270.51
667_T673_S0.6270.51
175_V180_L0.6260.51
564_L636_S0.6260.51
199_T300_S0.6260.51
243_T323_Y0.6250.51
630_G677_D0.6250.51
389_L612_V0.6250.51
310_P313_V0.6240.51
205_G236_L0.6240.51
222_D225_A0.6240.51
553_D617_M0.6230.51
56_V106_S0.6230.51
394_T459_E0.6230.51
447_C576_T0.6220.51
550_G625_T0.6210.50
190_N259_A0.6210.50
321_T669_D0.6210.50
556_L661_V0.6210.50
137_E403_Q0.6190.50
188_P332_E0.6190.50
51_S54_V0.6180.50
76_V535_V0.6170.50
629_P676_V0.6170.50
151_V419_D0.6160.50
168_N514_N0.6160.50
152_A438_A0.6160.50
174_L425_L0.6150.50
671_T684_D0.6140.50
78_V476_D0.6130.50
22_A296_L0.6120.49
213_D520_D0.6120.49
120_F135_V0.6100.49
435_A467_A0.6090.49
443_G446_A0.6090.49
647_R662_R0.6080.49
373_A577_D0.6070.49
457_A532_L0.6070.49
565_G580_P0.6060.49
606_S637_E0.6060.49
465_A599_T0.6060.49
241_N253_A0.6050.49
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603_H613_T0.6030.48
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278_I330_I0.6020.48
489_Y492_F0.6020.48
157_F163_G0.6010.48
234_E300_S0.6010.48
382_G385_I0.6010.48
538_R543_V0.6010.48
246_D319_V0.6000.48
12_V18_D0.6000.48
579_F681_V0.6000.48
493_E497_A0.5990.48
441_N444_W0.5980.48
624_A663_L0.5980.48
548_L618_V0.5980.48
460_N508_T0.5970.48
185_A252_A0.5970.48
484_E492_F0.5960.48
65_V76_V0.5950.47
625_T651_A0.5950.47
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468_G542_P0.5790.46
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281_D576_T0.5770.45
217_D221_A0.5770.45
589_A660_V0.5760.45
570_L574_G0.5760.45
200_G304_M0.5750.45
489_Y498_G0.5750.45
407_E410_A0.5740.45
205_G499_L0.5740.45
53_A474_A0.5740.45
560_H605_I0.5740.45
451_A582_A0.5720.45
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56_V194_L0.5710.45
526_I533_A0.5700.45
394_T608_G0.5700.45
644_V684_D0.5700.45
284_H327_C0.5700.45
454_Y566_G0.5700.45
692_R695_I0.5680.44
475_V536_G0.5670.44
47_F453_A0.5660.44
464_L474_A0.5660.44
168_N479_N0.5660.44
673_S680_T0.5650.44
444_W565_G0.5640.44
194_L264_A0.5630.44
222_D395_A0.5630.44
219_E423_L0.5620.44
432_T538_R0.5620.44
377_P676_V0.5620.44
231_P453_A0.5620.44
86_Y489_Y0.5620.44
496_V499_L0.5620.44
113_A436_L0.5610.44
53_A473_A0.5600.44
380_A612_V0.5600.44
599_T654_A0.5600.44
582_A640_G0.5600.44
117_A152_A0.5590.43
369_P490_G0.5590.43
406_H412_T0.5590.43
569_Y573_L0.5590.43
22_A293_M0.5590.43
148_V238_I0.5590.43
261_L283_V0.5580.43
129_R133_D0.5580.43
7_D205_G0.5580.43
556_L641_R0.5560.43
460_N478_L0.5550.43
556_L625_T0.5550.43
625_T694_V0.5540.43
387_A572_A0.5530.43
54_V199_T0.5510.43
659_P662_R0.5510.43
40_S80_S0.5510.43
131_L619_T0.5510.43
190_N265_S0.5500.42
300_S330_I0.5500.42
192_L256_L0.5500.42
457_A498_G0.5500.42
673_S676_V0.5500.42
377_P663_L0.5500.42
233_T236_L0.5490.42
551_D596_R0.5490.42
252_A276_A0.5490.42
265_S269_V0.5490.42
438_A531_T0.5490.42
217_D224_P0.5480.42
168_N515_V0.5480.42
550_G622_A0.5470.42
470_E588_D0.5470.42
603_H637_E0.5470.42
558_G638_C0.5440.42
378_D383_T0.5440.42
585_A588_D0.5440.42
599_T656_L0.5440.42
2_S212_E0.5430.42
181_V253_A0.5430.42
314_D592_E0.5430.42
71_D178_D0.5420.42
282_A328_S0.5420.42
279_T292_A0.5410.41
478_L532_L0.5410.41
39_S86_Y0.5410.41
669_D673_S0.5410.41
235_K239_E0.5390.41
496_V532_L0.5390.41
175_V179_R0.5380.41
651_A662_R0.5380.41
634_L674_V0.5380.41
602_V644_V0.5380.41
201_R297_L0.5380.41
39_S365_P0.5380.41
556_L610_L0.5360.41
500_A503_C0.5350.41
14_A353_T0.5350.41
550_G673_S0.5340.41
589_A599_T0.5340.41
143_G150_T0.5340.41
683_R691_H0.5330.41
132_L155_T0.5330.41
127_H130_Y0.5330.41
596_R601_A0.5330.41
195_V237_L0.5320.40
291_N447_C0.5320.40
578_Q581_A0.5320.40
87_V101_V0.5320.40
244_L248_D0.5310.40
213_D484_E0.5310.40
13_A370_Q0.5310.40
380_A631_L0.5300.40
39_S43_L0.5300.40
56_V263_G0.5300.40
454_Y505_A0.5300.40
503_C510_V0.5300.40
557_V660_V0.5290.40
467_A594_A0.5280.40
469_A536_G0.5280.40
25_A297_L0.5280.40
665_S675_T0.5280.40
154_A438_A0.5280.40
471_P536_G0.5280.40
262_G338_Y0.5270.40
600_L666_A0.5260.40
629_P633_A0.5260.40
258_A517_L0.5260.40
69_G684_D0.5250.40
419_D616_E0.5250.40
184_A251_V0.5230.39
350_A355_L0.5230.39
598_D652_L0.5230.39
140_S145_A0.5220.39
488_V496_V0.5220.39
87_V519_N0.5220.39
241_N244_L0.5220.39
336_G349_D0.5220.39
86_Y115_A0.5210.39
611_A634_L0.5210.39
329_V643_V0.5210.39
263_G511_V0.5200.39
649_A653_Q0.5200.39
229_G468_G0.5200.39
370_Q592_E0.5190.39
655_A673_S0.5190.39
633_A663_L0.5180.39
13_A687_T0.5180.39
205_G293_M0.5180.39
455_A582_A0.5180.39
97_V142_Y0.5170.39
496_V500_A0.5170.39
598_D654_A0.5170.39
644_V660_V0.5160.39
558_G563_G0.5160.39
114_L139_I0.5160.39
643_V671_T0.5160.39
28_E36_A0.5150.39
603_H617_M0.5150.39
38_R77_G0.5150.39
488_V498_G0.5150.39
10_R14_A0.5150.39
49_S54_V0.5150.39
627_T654_A0.5140.39
615_A626_V0.5140.39
75_T175_V0.5130.38
551_D647_R0.5130.38
598_D656_L0.5130.38
672_L678_D0.5120.38
321_T332_E0.5120.38
600_L617_M0.5120.38
231_P558_G0.5110.38
83_H94_A0.5110.38
669_D684_D0.5100.38
145_A404_Y0.5100.38
395_A554_L0.5100.38
683_R692_R0.5100.38
282_A430_D0.5100.38
156_Q393_N0.5090.38
614_L618_V0.5090.38
548_L551_D0.5080.38
390_S592_E0.5080.38
276_A333_V0.5070.38
457_A474_A0.5070.38
317_R328_S0.5070.38
293_M453_A0.5070.38
470_E473_A0.5060.38
558_G636_S0.5060.38
557_V658_V0.5060.38
582_A686_A0.5050.38
244_L319_V0.5050.38
85_S167_V0.5050.38
240_A532_L0.5040.37
385_I626_V0.5040.37
50_D507_D0.5040.37
675_T681_V0.5030.37
564_L569_Y0.5030.37
26_L355_L0.5030.37
207_A261_L0.5020.37
419_D604_D0.5020.37
195_V306_Y0.5020.37
28_E253_A0.5020.37
101_V238_I0.5010.37
555_V615_A0.5010.37
363_D366_S0.5010.37
16_G553_D0.5010.37
468_G594_A0.5010.37
208_S212_E0.5000.37
520_D525_P0.5000.37
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
4lgyA 1 0.9714 100 0.348 Contact Map
3viuA 1 0.9586 100 0.352 Contact Map
1vk3A 1 0.8214 100 0.457 Contact Map
2zodA 2 0.4114 100 0.841 Contact Map
3u0oA 2 0.4257 100 0.846 Contact Map
3fd5A 2 0.4614 100 0.858 Contact Map
2rb9A 2 0.4271 100 0.858 Contact Map
3vtiC 2 0.4114 100 0.863 Contact Map
3wjpA 2 0.4429 100 0.864 Contact Map
2z01A 2 0.4014 100 0.865 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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