GREMLIN Database
GATC - Glutamyl-tRNA(Gln) amidotransferase subunit C
UniProt: Q9HR44 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 91 (87)
Sequences: 2219 (1391)
Seq/√Len: 149.1

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
11_R26_V3.7891.00
6_D9_E2.9051.00
68_L73_A2.8981.00
69_D72_D2.8861.00
7_A27_D2.7071.00
79_E86_K2.6181.00
22_D25_D2.5331.00
70_Q83_G2.2831.00
8_E11_R2.0521.00
7_A26_V1.9231.00
69_D73_A1.8961.00
34_G38_E1.8401.00
29_V32_H1.8191.00
7_A11_R1.7511.00
73_A85_F1.7511.00
80_T83_G1.6981.00
74_L80_T1.6941.00
47_P50_D1.6581.00
72_D75_A1.6231.00
28_T32_H1.6161.00
32_H35_D1.5441.00
27_D30_V1.5341.00
34_G37_L1.4331.00
21_L26_V1.3591.00
66_D69_D1.3511.00
41_E44_E1.2981.00
21_L29_V1.2671.00
13_V17_A1.2371.00
39_H43_L1.2331.00
11_R23_D1.2231.00
7_A23_D1.2091.00
42_R45_E1.1881.00
4_A34_G1.1541.00
23_D26_V1.1411.00
64_I67_S1.1401.00
70_Q73_A1.1381.00
58_V86_K1.1090.99
27_D31_D1.0890.99
76_N85_F1.0880.99
38_E41_E1.0860.99
80_T84_R1.0780.99
10_I30_V1.0590.99
10_I33_C1.0440.99
30_V34_G1.0120.99
13_V32_H0.9890.99
43_L48_E0.9700.98
31_D35_D0.9560.98
35_D39_H0.9310.98
10_I14_A0.9090.98
15_D18_R0.8860.97
35_D38_E0.8830.97
4_A41_E0.8780.97
48_E51_A0.8240.96
22_D26_V0.8140.95
21_L42_R0.8080.95
39_H42_R0.8020.95
43_L47_P0.7990.95
74_L85_F0.7950.95
9_E14_A0.7900.95
29_V33_C0.7880.95
81_E86_K0.7880.95
70_Q74_L0.7790.94
57_N86_K0.7690.94
25_D28_T0.7670.94
5_V30_V0.7580.93
37_L89_N0.7550.93
10_I26_V0.7520.93
74_L77_A0.7520.93
19_L29_V0.7390.92
77_A85_F0.7380.92
9_E13_V0.7370.92
32_H36_I0.7270.92
40_F84_R0.7240.92
7_A30_V0.7220.92
28_T31_D0.7060.91
6_D41_E0.7040.91
24_E27_D0.6910.90
4_A37_L0.6840.89
19_L36_I0.6790.89
30_V40_F0.6730.89
18_R87_G0.6720.88
26_V30_V0.6640.88
43_L84_R0.6580.87
33_C87_G0.6410.86
10_I13_V0.6410.86
24_E28_T0.6380.86
13_V82_D0.6330.85
43_L46_V0.6320.85
13_V34_G0.6290.85
4_A90_V0.6220.84
9_E12_H0.6210.84
57_N68_L0.6160.84
59_M84_R0.6130.83
54_E88_P0.6100.83
78_P87_G0.6080.83
19_L86_K0.6030.82
76_N80_T0.6000.82
14_A78_P0.6000.82
54_E85_F0.5890.81
49_V52_E0.5880.81
15_D20_R0.5880.81
68_L72_D0.5690.79
14_A60_R0.5680.79
22_D27_D0.5680.79
67_S73_A0.5650.78
28_T35_D0.5580.77
14_A87_G0.5550.77
8_E23_D0.5520.77
39_H55_L0.5510.76
35_D41_E0.5490.76
17_A30_V0.5490.76
65_A68_L0.5490.76
41_E90_V0.5440.76
9_E37_L0.5400.75
5_V15_D0.5390.75
34_G88_P0.5360.74
46_V87_G0.5340.74
40_F87_G0.5270.73
21_L25_D0.5270.73
7_A28_T0.5240.73
19_L87_G0.5230.73
9_E30_V0.5210.72
27_D52_E0.5190.72
33_C51_A0.5160.72
55_L58_V0.5110.71
22_D60_R0.5080.71
37_L59_M0.5060.70
13_V76_N0.5030.70
12_H16_L0.5020.70
27_D50_D0.5000.69
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
3al0C 1 0.956 100 0.161 Contact Map
3kfuG 1 0.9451 100 0.17 Contact Map
3ip4C 1 0.956 100 0.197 Contact Map
3h0lC 1 0.9451 100 0.199 Contact Map
4wj3C 1 0.967 100 0.205 Contact Map
4n0hF 1 0.8791 99.9 0.273 Contact Map
1pzgA 4 0.5055 35.3 0.9 Contact Map
4cl3A 4 0.4725 19.9 0.911 Contact Map
1y6jA 2 0.4615 19.2 0.912 Contact Map
3d0oA 4 0.4396 18.5 0.913 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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