GREMLIN Database
DNLI - DNA ligase
UniProt: Q9HR35 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 561 (525)
Sequences: 2142 (1313)
Seq/√Len: 57.3

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
361_A365_D8.3601.00
440_T459_S8.3071.00
356_E361_A5.3781.00
298_P355_G4.4771.00
542_T545_T4.3861.00
462_D469_E4.3111.00
547_D551_R4.1321.00
365_D368_R3.9741.00
271_V279_N3.9511.00
349_A369_R3.8591.00
437_L460_A3.8021.00
263_V341_L3.7621.00
435_L552_V3.5681.00
251_A363_F3.5551.00
26_V30_F3.4741.00
263_V272_L3.4481.00
356_E369_R3.2411.00
346_C369_R3.0791.00
155_T158_E3.0791.00
349_A354_G3.0571.00
440_T470_T2.9121.00
393_A397_A2.7851.00
252_V392_I2.7791.00
398_T402_G2.7701.00
364_S413_A2.7601.00
315_L319_E2.7431.00
18_A21_D2.6571.00
462_D465_G2.5121.00
442_A453_L2.4931.00
493_H507_A2.4761.00
301_I343_A2.4501.00
493_H505_E2.4481.00
150_L162_L2.4471.00
368_R372_S2.4201.00
6_F10_A2.3801.00
388_D391_E2.3751.00
471_I552_V2.3271.00
90_D164_R2.3141.00
251_A412_P2.2841.00
123_G153_Q2.2831.00
70_R144_V2.2761.00
488_D492_P2.2531.00
5_S32_A2.1961.00
252_V409_L2.1701.00
387_D391_E2.1551.00
346_C373_V2.1541.00
297_A354_G2.1451.00
270_V288_V2.1431.00
266_D269_D2.1401.00
252_V407_I2.1251.00
332_A336_E2.1231.00
496_S503_D2.1101.00
266_D298_P2.0971.00
183_I211_A2.0761.00
214_S218_A2.0601.00
202_N207_V2.0451.00
362_P365_D2.0411.00
125_A129_A2.0251.00
367_H371_R2.0061.00
456_F490_L1.9761.00
307_A315_L1.9641.00
303_G341_L1.9431.00
439_V490_L1.9421.00
319_E322_K1.9301.00
384_L395_F1.8841.00
281_T288_V1.8571.00
119_L124_V1.8521.00
513_G535_V1.8511.00
261_V272_L1.8511.00
481_E484_A1.8461.00
16_T21_D1.8240.99
530_R533_R1.8200.99
64_C95_A1.8160.99
454_G483_L1.7860.99
371_R380_V1.7580.99
127_E146_L1.7570.99
391_E394_A1.7560.99
21_D24_A1.7470.99
485_A539_E1.7140.99
538_R541_K1.7120.99
456_F478_L1.7100.99
265_Y268_D1.7040.99
289_E293_N1.7010.99
468_F543_P1.6950.99
263_V291_V1.6740.99
469_E549_I1.6700.99
479_T482_E1.6380.99
434_T511_E1.6260.99
205_G209_E1.6210.99
23_V178_A1.6160.99
361_A369_R1.6030.99
461_R546_A1.5980.99
9_F13_I1.5960.99
309_D315_L1.5780.98
24_A28_E1.5770.98
28_E32_A1.5730.98
141_S145_T1.5520.98
261_V341_L1.5490.98
455_T474_V1.5300.98
154_C162_L1.5210.98
517_I527_Y1.5170.98
438_V509_V1.5140.98
151_F163_A1.5110.98
33_A36_D1.4940.98
448_R476_T1.4770.98
265_Y270_V1.4660.97
208_A211_A1.4590.97
200_V203_D1.4540.97
489_R493_H1.4530.97
299_V349_A1.4450.97
20_L23_V1.4440.97
27_A31_D1.4400.97
449_R475_A1.4320.97
241_T245_D1.4260.97
438_V546_A1.4070.97
431_D515_E1.4050.97
84_R94_V1.4050.97
120_T123_G1.4030.97
363_F367_H1.3970.97
514_Y529_L1.3940.96
382_E398_T1.3880.96
363_F414_A1.3870.96
417_T424_D1.3860.96
209_E213_D1.3840.96
448_R480_D1.3810.96
142_E145_T1.3710.96
348_H357_D1.3670.96
253_E367_H1.3660.96
494_V497_E1.3660.96
348_H355_G1.3650.96
68_L95_A1.3610.96
349_A355_G1.3540.96
200_V204_Y1.3490.96
301_I341_L1.3440.96
128_L166_V1.3420.96
455_T475_A1.3400.96
252_V386_T1.3380.96
519_A553_E1.3380.96
131_L143_K1.3330.95
203_D206_L1.3300.95
204_Y207_V1.3290.95
38_D43_F1.3190.95
134_A146_L1.3180.95
443_E457_L1.3140.95
484_A488_D1.3080.95
369_R372_S1.3050.95
442_A508_V1.3030.95
27_A185_E1.3030.95
511_E536_S1.2960.95
68_L81_I1.2940.95
495_R503_D1.2940.95
498_D523_Y1.2910.95
371_R383_V1.2870.95
65_Y76_V1.2870.95
9_F25_L1.2870.95
490_L504_I1.2850.94
343_A346_C1.2790.94
459_S468_F1.2720.94
527_Y553_E1.2720.94
343_A374_V1.2640.94
244_L248_H1.2620.94
392_I409_L1.2550.94
41_A179_V1.2540.94
74_R98_L1.2530.94
434_T535_V1.2520.94
66_T70_R1.2440.93
230_V517_I1.2350.93
119_L123_G1.2340.93
256_F381_S1.2320.93
507_A543_P1.2170.93
7_A158_E1.2010.92
483_L534_F1.1980.92
466_D544_T1.1980.92
71_A152_N1.1970.92
411_N424_D1.1910.92
307_A337_I1.1910.92
487_S491_E1.1830.92
527_Y556_A1.1810.92
9_F29_L1.1790.91
287_L341_L1.1750.91
245_D393_A1.1690.91
119_L154_C1.1690.91
80_D83_A1.1670.91
238_G242_D1.1660.91
346_C349_A1.1600.91
434_T513_G1.1460.90
398_T401_E1.1430.90
72_A98_L1.1430.90
254_T404_H1.1430.90
445_G449_R1.1350.90
68_L98_L1.1320.90
254_T402_G1.1310.90
201_S204_Y1.1310.90
43_F46_G1.1260.89
308_A312_G1.1240.89
180_R198_L1.1160.89
70_R148_F1.1110.89
127_E130_A1.1100.89
444_W502_V1.1030.88
489_R539_E1.0980.88
452_V484_A1.0960.88
13_I22_V1.0930.88
261_V305_A1.0930.88
131_L146_L1.0920.88
520_S523_Y1.0920.88
396_E432_V1.0900.88
24_A185_E1.0890.88
457_L470_T1.0850.88
93_A97_S1.0840.88
414_A425_W1.0830.88
320_I339_V1.0810.87
241_T244_L1.0780.87
449_R476_T1.0770.87
91_I446_E1.0750.87
259_A321_L1.0720.87
91_I163_A1.0720.87
363_F383_V1.0680.87
246_E423_K1.0680.87
243_A409_L1.0670.87
503_D506_P1.0640.87
509_V543_P1.0630.87
489_R508_V1.0580.86
541_K545_T1.0550.86
308_A340_E1.0510.86
463_A548_T1.0510.86
548_T551_R1.0470.86
433_E515_E1.0430.86
300_I359_L1.0410.85
364_S412_P1.0380.85
392_I395_F1.0360.85
16_T20_L1.0360.85
470_T523_Y1.0350.85
117_D123_G1.0320.85
16_T25_L1.0310.85
203_D208_A1.0310.85
5_S8_T1.0230.84
267_G297_A1.0200.84
515_E518_Q1.0170.84
149_G153_Q1.0150.84
122_S126_D1.0090.84
208_A212_R1.0060.83
313_D403_G1.0050.83
394_A398_T1.0050.83
25_L28_E1.0030.83
458_L474_V1.0000.83
506_P526_G0.9970.83
263_V270_V0.9970.83
6_F165_L0.9900.82
439_V510_L0.9880.82
270_V295_V0.9870.82
124_V150_L0.9860.82
509_V546_A0.9850.82
286_E323_R0.9840.82
254_T399_A0.9840.82
463_A550_E0.9840.82
259_A284_L0.9800.82
243_A246_E0.9780.82
293_N372_S0.9730.81
476_T532_P0.9710.81
272_L284_L0.9710.81
442_A490_L0.9690.81
520_S531_F0.9690.81
320_I323_R0.9680.81
284_L321_L0.9610.80
268_D297_A0.9560.80
234_L275_R0.9550.80
241_T389_A0.9540.80
187_F194_V0.9540.80
471_I529_L0.9530.80
361_A368_R0.9520.80
306_V342_H0.9470.79
490_L508_V0.9450.79
270_V291_V0.9450.79
299_V374_V0.9420.79
12_D28_E0.9420.79
227_G271_V0.9370.79
400_L433_E0.9360.79
414_A470_T0.9340.79
255_K304_E0.9320.78
145_T148_F0.9320.78
464_A550_E0.9310.78
27_A186_A0.9300.78
229_P234_L0.9290.78
227_G233_M0.9270.78
475_A482_E0.9270.78
430_P433_E0.9250.78
534_F537_V0.9230.78
368_R407_I0.9210.78
6_F121_V0.9210.78
93_A96_G0.9200.77
363_F412_P0.9180.77
386_T391_E0.9180.77
478_L534_F0.9170.77
449_R454_G0.9160.77
275_R477_G0.9130.77
130_A142_E0.9030.76
43_F47_R0.9020.76
141_S192_A0.9000.76
237_A263_V0.8990.76
473_K541_K0.8980.76
311_D314_P0.8980.76
160_R164_R0.8910.75
481_E485_A0.8900.75
69_S76_V0.8900.75
519_A556_A0.8870.75
85_L91_I0.8850.75
164_R170_M0.8850.75
28_E31_D0.8770.74
251_A383_V0.8770.74
461_R468_F0.8710.74
231_Q418_P0.8680.73
296_T354_G0.8640.73
103_Q448_R0.8570.72
167_L446_E0.8560.72
491_E494_V0.8540.72
378_S391_E0.8540.72
29_L40_V0.8520.72
65_Y91_I0.8520.72
57_L60_G0.8480.71
462_D553_E0.8450.71
130_A146_L0.8440.71
68_L72_A0.8410.71
96_G100_L0.8410.71
470_T524_S0.8390.71
260_R302_D0.8370.70
486_L489_R0.8360.70
443_E455_T0.8350.70
445_G457_L0.8350.70
223_G272_L0.8350.70
261_V306_V0.8340.70
410_K436_D0.8330.70
285_P323_R0.8320.70
247_W250_A0.8310.70
405_E427_K0.8310.70
442_A501_T0.8300.70
201_S206_L0.8290.70
238_G241_T0.8280.70
27_A187_F0.8250.69
478_L490_L0.8250.69
12_D25_L0.8240.69
369_R373_V0.8220.69
363_F408_M0.8190.69
439_V534_F0.8170.69
42_R50_P0.8170.69
385_V388_D0.8170.69
69_S81_I0.8160.69
433_E517_I0.8140.68
454_G476_T0.8130.68
275_R538_R0.8110.68
482_E485_A0.8100.68
160_R163_A0.8100.68
67_A71_A0.8020.67
514_Y517_I0.7970.67
384_L398_T0.7940.66
291_V341_L0.7930.66
233_M523_Y0.7920.66
478_L512_V0.7910.66
17_D21_D0.7900.66
179_V182_A0.7890.66
167_L528_A0.7880.66
13_I174_V0.7870.66
306_V314_P0.7860.66
158_E281_T0.7860.66
191_T194_V0.7850.66
308_A314_P0.7850.66
475_A501_T0.7850.66
180_R191_T0.7830.65
358_L369_R0.7830.65
289_E334_R0.7830.65
144_V148_F0.7820.65
124_V484_A0.7820.65
363_F417_T0.7780.65
253_E307_A0.7780.65
8_T15_A0.7770.65
7_A10_A0.7760.65
520_S530_R0.7760.65
304_E427_K0.7740.64
37_L42_R0.7740.64
442_A456_F0.7730.64
11_A157_R0.7730.64
93_A449_R0.7710.64
310_E338_S0.7710.64
454_G475_A0.7670.64
317_F323_R0.7640.63
545_T549_I0.7640.63
498_D501_T0.7640.63
275_R302_D0.7640.63
169_E446_E0.7620.63
246_E408_M0.7620.63
65_Y81_I0.7580.63
254_T382_E0.7540.62
88_T93_A0.7540.62
290_F372_S0.7540.62
280_V283_A0.7490.62
160_R273_Y0.7480.62
432_V437_L0.7470.62
210_T214_S0.7470.62
396_E426_L0.7460.62
123_G488_D0.7460.62
67_A459_S0.7440.61
326_R329_D0.7440.61
306_V431_D0.7430.61
431_D533_R0.7410.61
58_D92_G0.7400.61
464_A496_S0.7390.61
126_D387_D0.7380.61
7_A239_T0.7350.60
432_V515_E0.7340.60
62_Q403_G0.7310.60
389_A392_I0.7300.60
509_V541_K0.7300.60
322_K337_I0.7300.60
235_A260_R0.7300.60
8_T362_P0.7260.59
500_Q503_D0.7250.59
305_A320_I0.7250.59
233_M483_L0.7250.59
8_T12_D0.7240.59
441_G457_L0.7240.59
445_G473_K0.7210.59
328_H333_M0.7160.58
205_G462_D0.7150.58
129_A301_I0.7150.58
201_S207_V0.7130.58
263_V301_I0.7130.58
494_V503_D0.7120.58
198_L346_C0.7120.58
23_V185_E0.7110.58
384_L407_I0.7090.58
28_E35_S0.7070.57
405_E429_K0.7060.57
397_A555_L0.7050.57
443_E475_A0.7040.57
431_D514_Y0.7030.57
317_F320_I0.7000.57
264_H300_I0.7000.57
187_F399_A0.6990.57
329_D332_A0.6990.57
425_W541_K0.6980.56
257_D304_E0.6970.56
362_P512_V0.6970.56
10_A17_D0.6970.56
85_L446_E0.6940.56
471_I486_L0.6940.56
235_A445_G0.6920.56
24_A220_D0.6920.56
126_D297_A0.6910.56
167_L259_A0.6900.56
291_V299_V0.6890.56
474_V512_V0.6870.55
317_F511_E0.6860.55
204_Y208_A0.6850.55
443_E473_K0.6850.55
266_D400_L0.6810.55
126_D130_A0.6800.55
177_G183_I0.6800.55
298_P349_A0.6800.55
374_V378_S0.6790.54
272_L288_V0.6790.54
262_Q531_F0.6780.54
22_V174_V0.6780.54
378_S466_D0.6770.54
143_K158_E0.6760.54
435_L505_E0.6750.54
255_K427_K0.6740.54
237_A551_R0.6740.54
215_G218_A0.6730.54
394_A545_T0.6730.54
234_L302_D0.6720.54
368_R413_A0.6710.54
226_V266_D0.6710.54
11_A15_A0.6680.53
456_F510_L0.6670.53
43_F165_L0.6660.53
318_Q518_Q0.6660.53
520_S533_R0.6660.53
447_G454_G0.6650.53
331_A335_E0.6650.53
121_V124_V0.6600.52
189_V194_V0.6590.52
274_S432_V0.6590.52
189_V245_D0.6590.52
215_G219_L0.6590.52
212_R215_G0.6580.52
237_A428_R0.6560.52
259_A514_Y0.6560.52
62_Q529_L0.6560.52
99_D102_G0.6550.52
384_L388_D0.6540.52
200_V207_V0.6520.51
184_A272_L0.6500.51
367_H383_V0.6500.51
259_A280_V0.6500.51
460_A517_I0.6480.51
81_I84_R0.6480.51
6_F29_L0.6470.51
50_P486_L0.6470.51
234_L477_G0.6470.51
443_E501_T0.6450.51
543_P546_A0.6450.51
154_C158_E0.6450.51
119_L421_R0.6450.51
84_R97_S0.6450.51
318_Q433_E0.6440.51
171_R182_A0.6430.50
275_R445_G0.6410.50
239_T242_D0.6410.50
68_L360_D0.6410.50
322_K333_M0.6410.50
238_G431_D0.6400.50
516_E556_A0.6380.50
158_E529_L0.6370.50
396_E407_I0.6360.50
81_I91_I0.6350.50
191_T204_Y0.6340.49
168_G455_T0.6330.49
259_A446_E0.6320.49
307_A395_F0.6310.49
199_Q207_V0.6310.49
478_L483_L0.6300.49
239_T243_A0.6280.49
253_E273_Y0.6280.49
121_V125_A0.6260.49
397_A467_G0.6260.49
430_P523_Y0.6260.49
166_V371_R0.6250.48
117_D153_Q0.6240.48
268_D290_F0.6230.48
45_Q176_E0.6220.48
304_E405_E0.6210.48
173_G234_L0.6210.48
11_A14_E0.6200.48
385_V412_P0.6190.48
8_T289_E0.6180.48
226_V354_G0.6180.48
473_K533_R0.6170.48
38_D41_A0.6170.48
36_D346_C0.6160.48
551_R555_L0.6160.48
475_A498_D0.6140.47
50_P147_L0.6140.47
184_A194_V0.6130.47
322_K407_I0.6130.47
508_V539_E0.6130.47
92_G160_R0.6120.47
485_A489_R0.6120.47
89_G447_G0.6120.47
74_R84_R0.6110.47
278_E323_R0.6100.47
260_R477_G0.6090.47
5_S29_L0.6070.47
243_A354_G0.6070.47
457_L475_A0.6060.46
265_Y291_V0.6040.46
443_E500_Q0.6040.46
256_F433_E0.6030.46
520_S538_R0.6030.46
527_Y549_I0.6030.46
330_V335_E0.6010.46
473_K480_D0.6010.46
322_K326_R0.6000.46
321_L325_R0.6000.46
442_A499_G0.5990.46
127_E149_G0.5990.46
515_E533_R0.5970.45
203_D211_A0.5970.45
301_I439_V0.5970.45
265_Y298_P0.5970.45
147_L180_R0.5960.45
285_P520_S0.5950.45
231_Q545_T0.5940.45
523_Y526_G0.5940.45
302_D425_W0.5930.45
255_K436_D0.5930.45
42_R125_A0.5920.45
408_M423_K0.5920.45
365_D369_R0.5920.45
258_G429_K0.5910.45
523_Y528_A0.5900.45
23_V181_D0.5900.45
481_E492_P0.5900.45
521_P554_R0.5890.45
393_A550_E0.5890.45
63_L140_Q0.5890.45
375_D401_E0.5880.44
457_L474_V0.5880.44
235_A408_M0.5880.44
19_D22_V0.5870.44
244_L247_W0.5870.44
471_I514_Y0.5870.44
7_A11_A0.5860.44
40_V56_K0.5860.44
67_A225_E0.5850.44
360_D554_R0.5840.44
225_E228_R0.5840.44
459_S544_T0.5830.44
196_R202_N0.5820.44
8_T104_T0.5820.44
249_E364_S0.5820.44
181_D197_A0.5820.44
206_L210_T0.5810.44
297_A355_G0.5800.44
245_D309_D0.5800.44
84_R293_N0.5790.43
120_T147_L0.5790.43
236_Q424_D0.5790.43
171_R447_G0.5780.43
447_G526_G0.5780.43
34_D37_L0.5780.43
99_D105_G0.5770.43
508_V546_A0.5770.43
327_K517_I0.5760.43
194_V197_A0.5760.43
69_S82_E0.5760.43
488_D491_E0.5750.43
360_D415_P0.5750.43
8_T130_A0.5750.43
260_R275_R0.5740.43
442_A504_I0.5740.43
36_D287_L0.5730.43
329_D334_R0.5730.43
307_A444_W0.5720.43
281_T479_T0.5720.43
130_A133_A0.5720.43
373_V545_T0.5710.43
209_E216_T0.5710.43
511_E541_K0.5710.43
122_S377_A0.5700.43
366_R370_L0.5700.43
442_A446_E0.5700.43
474_V498_D0.5700.43
72_A168_G0.5690.42
214_S221_A0.5690.42
201_S459_S0.5680.42
124_V128_L0.5680.42
15_A24_A0.5680.42
346_C358_L0.5680.42
496_S506_P0.5670.42
368_R544_T0.5670.42
270_V340_E0.5670.42
456_F508_V0.5670.42
237_A426_L0.5670.42
229_P235_A0.5670.42
216_T462_D0.5660.42
83_A87_E0.5660.42
263_V378_S0.5660.42
461_R465_G0.5650.42
92_G159_A0.5630.42
30_F220_D0.5630.42
441_G500_Q0.5630.42
234_L538_R0.5630.42
444_W453_L0.5620.42
85_L88_T0.5620.42
271_V375_D0.5620.42
96_G160_R0.5620.42
298_P354_G0.5620.42
526_G538_R0.5610.42
44_V529_L0.5610.42
343_A516_E0.5610.42
470_T474_V0.5600.41
13_I25_L0.5600.41
258_G405_E0.5570.41
171_R523_Y0.5570.41
500_Q532_P0.5560.41
396_E428_R0.5560.41
10_A15_A0.5540.41
520_S526_G0.5540.41
211_A374_V0.5540.41
259_A274_S0.5540.41
17_D548_T0.5520.41
423_K514_Y0.5510.40
255_K410_K0.5510.40
263_V343_A0.5510.40
186_A340_E0.5510.40
259_A283_A0.5490.40
16_T156_S0.5480.40
20_L24_A0.5470.40
263_V305_A0.5460.40
9_F537_V0.5460.40
245_D313_D0.5450.40
257_D436_D0.5450.40
404_H408_M0.5440.40
283_A321_L0.5440.40
489_R507_A0.5440.40
495_R505_E0.5430.40
193_A300_I0.5430.40
38_D209_E0.5430.40
22_V27_A0.5430.40
510_L537_V0.5430.40
458_L502_V0.5420.40
421_R539_E0.5420.40
360_D379_A0.5420.40
360_D368_R0.5420.40
181_D191_T0.5400.39
335_E387_D0.5380.39
6_F459_S0.5370.39
255_K275_R0.5370.39
287_L290_F0.5370.39
399_A430_P0.5360.39
256_F452_V0.5360.39
47_R190_P0.5360.39
285_P288_V0.5360.39
359_L542_T0.5350.39
123_G127_E0.5350.39
251_A364_S0.5350.39
123_G130_A0.5340.39
301_I316_P0.5320.38
415_P481_E0.5320.38
310_E340_E0.5300.38
237_A321_L0.5300.38
172_I440_T0.5290.38
134_A139_S0.5290.38
283_A339_V0.5290.38
116_A153_Q0.5280.38
68_L159_A0.5280.38
314_P518_Q0.5270.38
483_L486_L0.5270.38
174_V277_M0.5270.38
183_I194_V0.5260.38
275_R304_E0.5260.38
368_R371_R0.5250.38
10_A42_R0.5250.38
198_L201_S0.5240.38
121_V132_A0.5240.38
284_L443_E0.5240.38
196_R200_V0.5240.38
383_V408_M0.5240.38
479_T555_L0.5230.38
274_S430_P0.5230.38
401_E465_G0.5230.38
242_D245_D0.5210.37
40_V47_R0.5210.37
17_D27_A0.5210.37
124_V358_L0.5210.37
228_R525_S0.5200.37
183_I492_P0.5200.37
269_D297_A0.5200.37
44_V146_L0.5190.37
435_L460_A0.5190.37
124_V162_L0.5180.37
425_W445_G0.5180.37
550_E553_E0.5170.37
191_T279_N0.5170.37
445_G480_D0.5170.37
236_Q426_L0.5170.37
301_I407_I0.5170.37
464_A555_L0.5160.37
60_G325_R0.5160.37
320_I432_V0.5160.37
146_L149_G0.5160.37
446_E454_G0.5140.37
474_V514_Y0.5140.37
197_A207_V0.5140.37
251_A385_V0.5140.37
37_L44_V0.5140.37
255_K405_E0.5130.37
41_A147_L0.5130.37
210_T300_I0.5130.37
237_A518_Q0.5120.36
63_L392_I0.5120.36
104_T134_A0.5120.36
128_L167_L0.5110.36
127_E153_Q0.5100.36
203_D210_T0.5100.36
437_L458_L0.5100.36
229_P445_G0.5100.36
496_S505_E0.5100.36
18_A271_V0.5100.36
395_F407_I0.5090.36
312_G371_R0.5090.36
528_A531_F0.5090.36
191_T341_L0.5080.36
474_V482_E0.5080.36
234_L447_G0.5080.36
477_G526_G0.5070.36
317_F531_F0.5060.36
300_I348_H0.5040.36
239_T244_L0.5040.36
306_V333_M0.5040.36
179_V247_W0.5030.36
287_L452_V0.5020.35
188_D193_A0.5010.35
130_A332_A0.5010.35
457_L532_P0.5010.35
275_R447_G0.5010.35
183_I550_E0.5010.35
273_Y381_S0.5000.35
296_T299_V0.5000.35
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
2cfmA 1 0.9768 100 0.207 Contact Map
3gdeA 1 0.9679 100 0.209 Contact Map
2hivA 1 0.9626 100 0.214 Contact Map
1x9nA 1 0.9554 100 0.239 Contact Map
3w1bA 1 0.934 100 0.246 Contact Map
3l2pA 1 0.9109 100 0.276 Contact Map
1vs0A 1 0.5223 100 0.565 Contact Map
1a0iA 1 0.5134 100 0.626 Contact Map
1p16A 1 0.5704 100 0.641 Contact Map
4pz7A 1 0.5686 100 0.647 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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