Q9HR30 - HALSA - GREMLIN Contacts

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Q9HR30 - DNA gyrase subunit B

UniProt:	Q9HR30	Sequences: MYIGSTDARGLHHLVYEVVDNSIDEALAGYCDRIDVTLHDDGSVSVTDDGRGIPVATHEEYDRPAVEVILTVLHAGGKFDAKSYQVSGGLHGVGVSVVNALSERLAVEVSRDGARYREQFERGEPVTDLQHVGDSDDSGTLIRFRPDSEIFETTAYDFSTLENRLRELAFLNSGVEITLTDERGDEPTQSTFEYEGGIREFVEYLNETRNALHDDVIYFQGEDDGISVEIAMQASEDVQSSTHAFANNINTREGGTHLTGFKTALTRTVNDYANDNNLLSELDGENLTGDDIREGLTAVISVKHPDPQFEGQTKTKLGNSEVRGIVERAVNDGLGTYFEENPATAKAVVRTAVEAAKARKAAKKAEELTRRKSALGSTSLPGKLADCQSKAPEDAELFVVEGDSAGGSAKQGRNPGFQAILPLGGKILNVEKHRLDRILEHDELRHIITALGTGIGDEFDIDELRYENIIMMTDADVDGAHIRTLLLTFFYRHMKPLLEAGYVYAAQPPLYRIRYRGNTYDAMTEADRERIVEEQCNGNPTQVQRFKGLGEMNPQQLWDTTMDPENRILKRITVEDAAAADKMFSVLMGDAVEPRKQFIQERAGDAEWVDI	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	611 (600)
Sequences:	4878 (2040)
Seq/√Len:	83.3

ECOLI - GYRB PARE
BACSU - GYRB PARE
HALSA - Q9HR30

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
32_D	49_D	6.420	1.00
114_A	131_H	4.418	1.00
18_V	95_V	4.255	1.00
180_T	189_Q	3.998	1.00
103_E	145_R	3.961	1.00
39_H	45_S	3.707	1.00
106_A	119_Q	3.633	1.00
146_P	156_Y	3.544	1.00
522_A	531_I	3.470	1.00
121_E	126_V	3.358	1.00
104_R	145_R	3.271	1.00
47_T	141_L	3.130	1.00
176_E	191_T	3.108	1.00
389_S	394_D	3.053	1.00
563_D	566_N	2.964	1.00
33_R	176_E	2.954	1.00
467_E	502_Y	2.931	1.00
110_S	137_D	2.924	1.00
106_A	117_R	2.841	1.00
66_V	107_V	2.803	1.00
70_L	142_I	2.726	1.00
66_V	129_L	2.717	1.00
61_Y	68_V	2.713	1.00
39_H	182_E	2.712	1.00
104_R	119_Q	2.686	1.00
80_D	83_S	2.633	1.00
15_V	161_L	2.624	1.00
169_A	194_Y	2.606	1.00
391_A	394_D	2.592	1.00
117_R	130_Q	2.591	1.00
45_S	143_R	2.585	1.00
108_E	141_L	2.585	1.00
107_V	142_I	2.563	1.00
35_D	178_T	2.562	1.00
464_L	502_Y	2.541	1.00
39_H	143_R	2.510	1.00
127_T	130_Q	2.460	1.00
33_R	49_D	2.434	1.00
274_N	286_N	2.407	1.00
108_E	117_R	2.371	1.00
114_A	134_D	2.345	1.00
397_L	451_L	2.339	1.00
66_V	109_V	2.338	1.00
36_V	165_L	2.332	1.00
35_D	47_T	2.310	1.00
173_S	220_Q	2.310	1.00
116_Y	131_H	2.309	1.00
55_V	116_Y	2.305	1.00
158_F	190_S	2.282	1.00
38_L	44_V	2.257	1.00
230_I	300_I	2.250	1.00
511_Y	525_E	2.248	1.00
602_R	605_D	2.246	1.00
40_D	182_E	2.239	1.00
392_P	467_E	2.224	1.00
15_V	44_V	2.197	1.00
507_Q	570_K	2.195	1.00
131_H	134_D	2.184	1.00
63_R	67_E	2.179	1.00
108_E	115_R	2.158	1.00
103_E	148_S	2.130	1.00
447_I	451_L	2.124	1.00
176_E	193_E	2.102	1.00
23_I	175_V	2.096	1.00
31_C	49_D	2.084	1.00
110_S	115_R	2.074	1.00
597_Q	601_E	2.072	1.00
271_D	275_D	2.069	1.00
122_R	149_E	2.066	1.00
218_Y	229_E	2.044	1.00
470_I	569_L	2.043	1.00
45_S	141_L	2.042	1.00
253_E	315_T	2.040	1.00
158_F	179_L	2.036	1.00
495_K	499_E	2.028	1.00
371_R	374_A	2.022	1.00
118_E	125_P	2.007	1.00
496_P	499_E	2.004	1.00
106_A	143_R	2.003	1.00
268_T	331_N	2.002	1.00
108_E	143_R	1.984	1.00
385_A	410_K	1.964	1.00
388_Q	415_P	1.943	1.00
53_I	69_I	1.941	1.00
200_E	203_E	1.935	1.00
39_H	43_S	1.884	1.00
119_Q	126_V	1.881	1.00
451_L	469_I	1.869	1.00
399_V	447_I	1.861	1.00
244_A	258_L	1.860	1.00
246_A	304_H	1.845	1.00
399_V	423_L	1.844	1.00
514_R	519_T	1.844	1.00
35_D	180_T	1.823	1.00
497_L	503_V	1.811	1.00
56_A	112_D	1.810	1.00
408_S	554_P	1.795	1.00
269_V	338_F	1.792	1.00
110_S	141_L	1.783	1.00
323_R	327_E	1.769	1.00
166_R	204_Y	1.764	1.00
222_E	227_S	1.751	1.00
33_R	178_T	1.747	1.00
524_T	527_D	1.740	1.00
63_R	72_V	1.737	1.00
226_I	325_I	1.735	1.00
287_L	352_A	1.735	1.00
520_Y	534_E	1.731	1.00
221_G	329_A	1.723	1.00
37_T	182_E	1.718	1.00
70_L	95_V	1.703	1.00
37_T	47_T	1.700	1.00
210_N	236_E	1.698	1.00
244_A	251_T	1.677	1.00
487_L	503_V	1.669	1.00
119_Q	127_T	1.665	1.00
16_Y	161_L	1.664	1.00
505_A	572_I	1.633	1.00
341_N	344_T	1.630	1.00
579_A	582_K	1.629	1.00
337_Y	341_N	1.612	1.00
178_T	191_T	1.608	1.00
158_F	192_F	1.590	1.00
162_E	190_S	1.586	1.00
115_R	133_G	1.584	1.00
451_L	464_L	1.581	1.00
56_A	65_A	1.570	1.00
117_R	132_V	1.569	1.00
513_I	531_I	1.561	1.00
199_R	203_E	1.561	1.00
460_D	463_E	1.553	1.00
272_Y	345_A	1.535	1.00
44_V	156_Y	1.532	1.00
226_I	322_V	1.531	1.00
261_F	298_A	1.531	1.00
37_T	180_T	1.530	1.00
515_Y	540_P	1.529	1.00
334_L	338_F	1.520	0.99
273_A	279_L	1.518	0.99
222_E	225_G	1.517	0.99
95_V	105_L	1.510	0.99
170_F	204_Y	1.488	0.99
206_N	233_Q	1.477	0.99
393_E	467_E	1.476	0.99
261_F	300_I	1.471	0.99
322_V	325_I	1.467	0.99
19_V	46_V	1.456	0.99
232_M	296_L	1.456	0.99
389_S	395_A	1.449	0.99
70_L	105_L	1.448	0.99
104_R	121_E	1.433	0.99
7_D	320_S	1.420	0.99
591_A	594_P	1.412	0.99
56_A	111_R	1.399	0.99
528_R	532_V	1.398	0.99
289_G	293_R	1.392	0.99
47_T	137_D	1.373	0.99
436_D	440_E	1.371	0.99
527_D	530_R	1.368	0.99
43_S	145_R	1.368	0.99
217_I	232_M	1.367	0.99
496_P	500_A	1.365	0.99
395_A	467_E	1.357	0.99
220_Q	229_E	1.357	0.99
424_G	443_E	1.356	0.99
125_P	128_D	1.352	0.99
76_G	79_F	1.350	0.99
115_R	135_S	1.350	0.99
215_D	344_T	1.346	0.99
120_F	125_P	1.323	0.99
397_L	447_I	1.318	0.99
198_I	218_Y	1.316	0.99
173_S	229_E	1.314	0.98
206_N	297_T	1.305	0.98
68_V	72_V	1.301	0.98
294_E	355_A	1.291	0.98
469_I	490_F	1.289	0.98
544_Q	556_Q	1.284	0.98
442_D	446_H	1.283	0.98
105_L	142_I	1.282	0.98
520_Y	531_I	1.279	0.98
178_T	189_Q	1.268	0.98
486_L	490_F	1.259	0.98
461_I	500_A	1.259	0.98
246_A	251_T	1.259	0.98
512_R	519_T	1.256	0.98
530_R	534_E	1.255	0.98
427_I	444_L	1.253	0.98
577_A	580_A	1.251	0.98
596_K	600_Q	1.251	0.98
453_T	459_F	1.241	0.98
88_G	249_I	1.240	0.98
443_E	446_H	1.231	0.98
37_T	45_S	1.227	0.98
120_F	127_T	1.222	0.98
57_T	62_D	1.221	0.98
199_R	218_Y	1.221	0.98
43_S	146_P	1.220	0.98
23_I	168_L	1.215	0.97
31_C	34_I	1.213	0.97
70_L	107_V	1.213	0.97
26_A	175_V	1.206	0.97
490_F	503_V	1.201	0.97
392_P	395_A	1.199	0.97
253_E	311_G	1.199	0.97
42_G	155_A	1.193	0.97
242_T	262_K	1.192	0.97
110_S	138_S	1.189	0.97
333_G	336_T	1.189	0.97
38_L	42_G	1.188	0.97
394_D	416_G	1.188	0.97
219_F	230_I	1.185	0.97
371_R	386_D	1.183	0.97
120_F	129_L	1.183	0.97
145_R	148_S	1.181	0.97
513_I	522_A	1.178	0.97
115_R	132_V	1.177	0.97
304_H	322_V	1.175	0.97
424_G	427_I	1.175	0.97
30_Y	51_R	1.174	0.97
252_R	315_T	1.172	0.97
162_E	192_F	1.172	0.97
118_E	127_T	1.172	0.97
281_E	286_N	1.171	0.97
227_S	303_K	1.167	0.97
411_Q	554_P	1.167	0.97
22_S	142_I	1.163	0.97
274_N	281_E	1.159	0.97
274_N	284_G	1.158	0.97
238_V	370_R	1.150	0.96
114_A	133_G	1.150	0.96
242_T	298_A	1.149	0.96
19_V	165_L	1.149	0.96
157_D	160_T	1.142	0.96
559_D	563_D	1.140	0.96
513_I	528_R	1.128	0.96
394_D	417_F	1.127	0.96
311_G	318_G	1.125	0.96
558_W	564_P	1.123	0.96
529_E	533_E	1.118	0.96
388_Q	416_G	1.117	0.96
520_Y	527_D	1.116	0.96
15_V	19_V	1.113	0.96
427_I	473_T	1.111	0.96
47_T	110_S	1.103	0.96
263_T	327_E	1.103	0.96
269_V	292_I	1.103	0.96
338_F	345_A	1.101	0.95
266_T	289_G	1.100	0.95
119_Q	130_Q	1.099	0.95
453_T	464_L	1.098	0.95
43_S	143_R	1.098	0.95
226_I	304_H	1.097	0.95
112_D	116_Y	1.095	0.95
396_E	470_I	1.094	0.95
522_A	528_R	1.093	0.95
109_V	129_L	1.084	0.95
347_A	350_R	1.077	0.95
483_R	505_A	1.075	0.95
351_T	370_R	1.074	0.95
386_D	465_R	1.074	0.95
576_D	579_A	1.072	0.95
435_L	439_L	1.068	0.95
158_F	162_E	1.066	0.95
39_H	42_G	1.063	0.95
228_V	329_A	1.060	0.94
165_L	179_L	1.058	0.94
399_V	443_E	1.058	0.94
453_T	461_I	1.056	0.94
336_T	340_E	1.053	0.94
330_V	334_L	1.052	0.94
417_F	564_P	1.051	0.94
228_V	325_I	1.049	0.94
42_G	145_R	1.048	0.94
43_S	104_R	1.046	0.94
302_V	322_V	1.042	0.94
519_T	522_A	1.042	0.94
311_G	315_T	1.039	0.94
522_A	527_D	1.035	0.94
148_S	154_T	1.027	0.93
310_E	315_T	1.022	0.93
204_Y	582_K	1.017	0.93
22_S	70_L	1.017	0.93
215_D	341_N	1.014	0.93
464_L	500_A	1.012	0.93
64_P	68_V	1.012	0.93
528_R	541_T	1.011	0.93
310_E	318_G	1.009	0.93
246_A	302_V	1.009	0.93
381_P	386_D	1.004	0.93
111_R	138_S	1.003	0.93
308_Q	318_G	1.002	0.93
273_A	349_V	1.000	0.93
424_G	442_D	0.998	0.92
122_R	147_D	0.996	0.92
207_E	582_K	0.996	0.92
196_G	199_R	0.995	0.92
327_E	331_N	0.993	0.92
251_T	318_G	0.993	0.92
166_R	194_Y	0.987	0.92
582_K	586_V	0.983	0.92
271_D	274_N	0.982	0.92
471_M	490_F	0.978	0.92
115_R	137_D	0.975	0.92
161_L	165_L	0.972	0.91
196_G	200_E	0.972	0.91
593_E	597_Q	0.969	0.91
358_A	362_A	0.968	0.91
532_V	543_V	0.964	0.91
251_T	311_G	0.964	0.91
491_Y	580_A	0.962	0.91
103_E	149_E	0.962	0.91
58_H	65_A	0.959	0.91
274_N	279_L	0.955	0.91
529_E	532_V	0.952	0.91
162_E	179_L	0.951	0.91
110_S	135_S	0.948	0.90
55_V	111_R	0.945	0.90
324_G	328_R	0.945	0.90
95_V	107_V	0.943	0.90
53_I	70_L	0.943	0.90
58_H	63_R	0.942	0.90
292_I	352_A	0.942	0.90
445_R	449_T	0.939	0.90
427_I	446_H	0.939	0.90
26_A	31_C	0.938	0.90
264_A	268_T	0.936	0.90
259_T	263_T	0.932	0.90
14_L	98_V	0.930	0.90
33_R	191_T	0.927	0.89
427_I	441_H	0.926	0.89
63_R	68_V	0.925	0.89
395_A	502_Y	0.924	0.89
383_K	403_D	0.923	0.89
332_D	336_T	0.923	0.89
427_I	443_E	0.920	0.89
18_V	70_L	0.919	0.89
546_F	556_Q	0.918	0.89
358_A	365_A	0.918	0.89
291_D	359_R	0.918	0.89
238_V	351_T	0.917	0.89
583_M	586_V	0.916	0.89
36_V	179_L	0.915	0.89
277_N	281_E	0.915	0.89
558_W	563_D	0.913	0.89
109_V	140_T	0.908	0.88
431_E	492_R	0.907	0.88
115_R	131_H	0.905	0.88
234_A	292_I	0.904	0.88
53_I	142_I	0.903	0.88
60_E	124_E	0.903	0.88
267_R	327_E	0.902	0.88
27_L	31_C	0.897	0.88
279_L	284_G	0.893	0.88
273_A	287_L	0.892	0.88
385_A	415_P	0.890	0.87
279_L	286_N	0.890	0.87
259_T	327_E	0.885	0.87
531_I	535_Q	0.882	0.87
38_L	179_L	0.882	0.87
213_H	344_T	0.878	0.87
441_H	446_H	0.878	0.87
32_D	176_E	0.877	0.87
95_V	142_I	0.876	0.87
117_R	127_T	0.875	0.87
118_E	129_L	0.873	0.86
65_A	68_V	0.872	0.86
555_Q	563_D	0.870	0.86
447_I	473_T	0.869	0.86
196_G	203_E	0.869	0.86
64_P	129_L	0.868	0.86
448_I	489_F	0.866	0.86
36_V	177_I	0.865	0.86
57_T	61_Y	0.865	0.86
57_T	63_R	0.865	0.86
343_A	347_A	0.864	0.86
170_F	194_Y	0.864	0.86
537_N	540_P	0.861	0.86
246_A	318_G	0.860	0.86
512_R	556_Q	0.858	0.85
259_T	323_R	0.855	0.85
585_S	591_A	0.855	0.85
398_F	417_F	0.854	0.85
8_A	157_D	0.854	0.85
371_R	376_G	0.849	0.85
414_N	417_F	0.847	0.85
59_E	62_D	0.844	0.84
199_R	215_D	0.843	0.84
573_T	577_A	0.843	0.84
59_E	65_A	0.841	0.84
63_R	125_P	0.839	0.84
462_D	500_A	0.838	0.84
220_Q	227_S	0.835	0.84
168_L	172_N	0.832	0.84
443_E	473_T	0.831	0.84
42_G	156_Y	0.831	0.84
147_D	150_I	0.831	0.84
350_R	354_E	0.827	0.83
253_E	316_K	0.827	0.83
56_A	116_Y	0.826	0.83
439_L	444_L	0.807	0.82
81_A	306_D	0.806	0.82
228_V	326_V	0.806	0.82
472_M	506_A	0.806	0.82
574_V	580_A	0.804	0.81
579_A	583_M	0.803	0.81
535_Q	538_G	0.803	0.81
410_K	556_Q	0.803	0.81
411_Q	553_N	0.802	0.81
560_T	567_R	0.801	0.81
251_T	310_E	0.800	0.81
319_N	322_V	0.799	0.81
230_I	261_F	0.798	0.81
483_R	507_Q	0.795	0.81
23_I	177_I	0.794	0.81
382_G	415_P	0.794	0.81
105_L	118_E	0.793	0.81
246_A	309_F	0.793	0.81
244_A	311_G	0.793	0.81
58_H	68_V	0.792	0.81
242_T	258_L	0.786	0.80
270_N	274_N	0.784	0.80
331_N	335_G	0.784	0.80
519_T	559_D	0.782	0.80
110_S	136_D	0.780	0.80
230_I	330_V	0.779	0.79
112_D	131_H	0.778	0.79
61_Y	72_V	0.776	0.79
213_H	234_A	0.775	0.79
244_A	318_G	0.774	0.79
122_R	150_I	0.773	0.79
513_I	535_Q	0.773	0.79
30_Y	124_E	0.773	0.79
49_D	137_D	0.768	0.78
387_C	465_R	0.767	0.78
216_V	231_A	0.767	0.78
166_R	170_F	0.765	0.78
525_E	529_E	0.765	0.78
522_A	535_Q	0.764	0.78
581_D	585_S	0.763	0.78
398_F	569_L	0.762	0.78
447_I	489_F	0.761	0.78
442_D	445_R	0.761	0.78
597_Q	600_Q	0.759	0.78
16_Y	160_T	0.758	0.78
55_V	66_V	0.755	0.77
594_P	597_Q	0.754	0.77
515_Y	539_N	0.754	0.77
456_G	493_H	0.753	0.77
27_L	179_L	0.752	0.77
337_Y	344_T	0.752	0.77
598_F	603_A	0.751	0.77
103_E	122_R	0.750	0.77
274_N	282_L	0.750	0.77
346_K	350_R	0.750	0.77
392_P	502_Y	0.749	0.77
32_D	36_V	0.749	0.77
213_H	233_Q	0.748	0.77
381_P	465_R	0.747	0.77
72_V	120_F	0.745	0.76
263_T	323_R	0.745	0.76
148_S	155_A	0.743	0.76
41_D	145_R	0.741	0.76
114_A	132_V	0.740	0.76
533_E	537_N	0.739	0.76
389_S	416_G	0.738	0.76
430_V	438_I	0.736	0.75
424_G	444_L	0.735	0.75
308_Q	319_N	0.734	0.75
531_I	534_E	0.733	0.75
493_H	523_M	0.732	0.75
104_R	126_V	0.732	0.75
5_S	318_G	0.732	0.75
453_T	494_M	0.731	0.75
382_G	450_A	0.731	0.75
345_A	349_V	0.731	0.75
103_E	147_D	0.730	0.75
202_V	299_V	0.729	0.75
251_T	308_Q	0.728	0.75
451_L	503_V	0.728	0.75
520_Y	535_Q	0.728	0.75
281_E	284_G	0.727	0.75
515_Y	535_Q	0.727	0.75
564_P	567_R	0.727	0.75
368_L	371_R	0.723	0.74
268_T	335_G	0.723	0.74
358_A	369_T	0.722	0.74
451_L	467_E	0.721	0.74
203_E	216_V	0.719	0.74
244_A	308_Q	0.719	0.74
380_L	415_P	0.717	0.74
361_A	365_A	0.717	0.74
213_H	216_V	0.715	0.73
526_A	529_E	0.713	0.73
267_R	331_N	0.712	0.73
200_E	446_H	0.712	0.73
472_M	562_M	0.711	0.73
75_A	96_S	0.709	0.73
409_A	420_I	0.709	0.73
226_I	305_P	0.708	0.73
523_M	533_E	0.708	0.73
225_G	305_P	0.708	0.73
75_A	79_F	0.706	0.72
253_E	320_S	0.705	0.72
556_Q	559_D	0.705	0.72
250_N	258_L	0.703	0.72
106_A	121_E	0.702	0.72
398_F	558_W	0.702	0.72
261_F	330_V	0.701	0.72
115_R	134_D	0.701	0.72
66_V	118_E	0.700	0.72
67_E	118_E	0.698	0.72
116_Y	138_S	0.698	0.72
393_E	502_Y	0.698	0.72
258_L	268_T	0.698	0.72
395_A	464_L	0.698	0.72
584_F	588_M	0.697	0.71
147_D	251_T	0.695	0.71
144_F	156_Y	0.694	0.71
115_R	136_D	0.692	0.71
354_E	370_R	0.691	0.71
104_R	143_R	0.691	0.71
210_N	591_A	0.691	0.71
292_I	440_E	0.691	0.71
307_P	386_D	0.691	0.71
446_H	449_T	0.690	0.71
354_E	357_K	0.689	0.71
1_M	4_G	0.687	0.70
240_S	293_R	0.687	0.70
69_I	142_I	0.687	0.70
41_D	143_R	0.686	0.70
135_S	138_S	0.686	0.70
203_E	215_D	0.685	0.70
167_E	201_F	0.685	0.70
119_Q	145_R	0.684	0.70
173_S	218_Y	0.682	0.70
526_A	530_R	0.681	0.70
435_L	438_I	0.680	0.70
5_S	10_G	0.680	0.70
562_M	567_R	0.679	0.69
62_D	124_E	0.678	0.69
232_M	265_L	0.677	0.69
57_T	60_E	0.677	0.69
278_L	282_L	0.675	0.69
253_E	310_E	0.675	0.69
398_F	468_N	0.673	0.69
40_D	185_D	0.672	0.69
496_P	574_V	0.672	0.69
420_I	562_M	0.672	0.69
507_Q	568_I	0.671	0.69
521_D	556_Q	0.670	0.68
498_L	503_V	0.670	0.68
19_V	36_V	0.669	0.68
381_P	446_H	0.667	0.68
588_M	592_V	0.666	0.68
244_A	300_I	0.666	0.68
180_T	185_D	0.666	0.68
14_L	251_T	0.665	0.68
285_E	360_K	0.664	0.68
480_A	556_Q	0.664	0.68
353_V	363_K	0.664	0.68
268_T	334_L	0.663	0.68
534_E	538_G	0.663	0.68
430_V	444_L	0.660	0.67
530_R	533_E	0.659	0.67
137_D	141_L	0.658	0.67
37_T	43_S	0.658	0.67
262_K	293_R	0.656	0.67
145_R	156_Y	0.656	0.67
315_T	319_N	0.655	0.67
179_L	190_S	0.654	0.67
294_E	351_T	0.652	0.66
161_L	177_I	0.652	0.66
484_T	584_F	0.651	0.66
277_N	280_S	0.650	0.66
387_C	598_F	0.649	0.66
469_I	503_V	0.648	0.66
256_T	320_S	0.648	0.66
513_I	532_V	0.647	0.66
448_I	455_I	0.646	0.66
211_A	233_Q	0.645	0.65
544_Q	558_W	0.644	0.65
68_V	201_F	0.642	0.65
221_G	333_G	0.641	0.65
65_A	83_S	0.641	0.65
79_F	91_H	0.640	0.65
598_F	602_R	0.640	0.65
498_L	574_V	0.640	0.65
552_M	557_L	0.639	0.65
461_I	464_L	0.639	0.65
219_F	330_V	0.639	0.65
70_L	118_E	0.637	0.65
64_P	125_P	0.637	0.65
33_R	47_T	0.635	0.64
216_V	344_T	0.635	0.64
388_Q	395_A	0.634	0.64
273_A	277_N	0.633	0.64
278_L	349_V	0.633	0.64
448_I	454_G	0.632	0.64
206_N	235_S	0.631	0.64
64_P	128_D	0.631	0.64
307_P	430_V	0.631	0.64
282_L	285_E	0.628	0.63
561_T	567_R	0.626	0.63
219_F	447_I	0.624	0.63
389_S	392_P	0.624	0.63
57_T	64_P	0.623	0.63
379_S	449_T	0.623	0.63
369_T	374_A	0.623	0.63
70_L	125_P	0.622	0.63
438_I	444_L	0.621	0.63
523_M	531_I	0.621	0.63
397_L	469_I	0.621	0.63
546_F	559_D	0.620	0.62
515_Y	541_T	0.620	0.62
56_A	68_V	0.619	0.62
276_N	349_V	0.619	0.62
45_S	104_R	0.619	0.62
489_F	494_M	0.618	0.62
168_L	175_V	0.618	0.62
45_S	182_E	0.617	0.62
9_R	252_R	0.616	0.62
103_E	119_Q	0.616	0.62
424_G	473_T	0.616	0.62
42_G	154_T	0.616	0.62
527_D	568_I	0.615	0.62
278_L	353_V	0.615	0.62
454_G	459_F	0.614	0.62
113_G	136_D	0.614	0.62
174_G	193_E	0.611	0.61
56_A	59_E	0.611	0.61
424_G	447_I	0.611	0.61
428_L	433_H	0.611	0.61
390_K	530_R	0.610	0.61
528_R	543_V	0.610	0.61
397_L	453_T	0.609	0.61
428_L	438_I	0.609	0.61
385_A	556_Q	0.608	0.61
195_E	215_D	0.608	0.61
412_G	480_A	0.606	0.61
253_E	319_N	0.605	0.61
532_V	535_Q	0.604	0.60
396_E	468_N	0.604	0.60
55_V	58_H	0.603	0.60
63_R	128_D	0.603	0.60
424_G	439_L	0.603	0.60
17_E	21_N	0.601	0.60
118_E	128_D	0.601	0.60
18_V	97_V	0.600	0.60
581_D	584_F	0.600	0.60
523_M	537_N	0.599	0.60
302_V	326_V	0.599	0.60
360_K	363_K	0.598	0.60
412_G	427_I	0.598	0.60
492_R	581_D	0.597	0.60
538_G	541_T	0.597	0.60
363_K	367_E	0.596	0.59
575_E	579_A	0.595	0.59
593_E	596_K	0.594	0.59
483_R	570_K	0.594	0.59
81_A	246_A	0.593	0.59
70_L	140_T	0.593	0.59
246_A	311_G	0.592	0.59
380_L	385_A	0.592	0.59
116_Y	120_F	0.592	0.59
395_A	416_G	0.591	0.59
428_L	441_H	0.591	0.59
410_K	415_P	0.591	0.59
523_M	568_I	0.589	0.59
264_A	334_L	0.589	0.59
282_L	286_N	0.588	0.58
464_L	497_L	0.588	0.58
258_L	377_S	0.588	0.58
414_N	564_P	0.585	0.58
168_L	248_N	0.584	0.58
424_G	446_H	0.583	0.58
124_E	147_D	0.583	0.58
371_R	395_A	0.582	0.58
473_T	483_R	0.580	0.57
128_D	131_H	0.579	0.57
279_L	282_L	0.579	0.57
82_K	85_Q	0.579	0.57
84_Y	305_P	0.578	0.57
189_Q	193_E	0.577	0.57
35_D	45_S	0.577	0.57
61_Y	64_P	0.576	0.57
397_L	464_L	0.576	0.57
391_A	395_A	0.576	0.57
58_H	61_Y	0.575	0.57
353_V	357_K	0.575	0.57
377_S	449_T	0.575	0.57
106_A	126_V	0.574	0.57
115_R	120_F	0.574	0.57
3_I	10_G	0.574	0.57
310_E	316_K	0.573	0.56
371_R	375_L	0.572	0.56
199_R	216_V	0.572	0.56
409_A	472_M	0.572	0.56
111_R	228_V	0.571	0.56
462_D	467_E	0.571	0.56
164_R	168_L	0.570	0.56
35_D	176_E	0.570	0.56
589_G	599_I	0.570	0.56
159_S	162_E	0.569	0.56
211_A	216_V	0.569	0.56
273_A	281_E	0.568	0.56
176_E	195_E	0.568	0.56
262_K	289_G	0.567	0.56
411_Q	415_P	0.566	0.56
274_N	523_M	0.566	0.56
22_S	34_I	0.565	0.55
121_E	127_T	0.564	0.55
243_H	578_A	0.564	0.55
412_G	558_W	0.564	0.55
427_I	442_D	0.563	0.55
413_R	418_Q	0.563	0.55
287_L	353_V	0.563	0.55
295_G	351_T	0.562	0.55
386_D	395_A	0.562	0.55
7_D	315_T	0.561	0.55
444_L	489_F	0.561	0.55
10_G	313_T	0.561	0.55
9_R	310_E	0.559	0.55
238_V	354_E	0.559	0.55
81_A	305_P	0.558	0.54
208_T	585_S	0.558	0.54
423_L	486_L	0.558	0.54
25_E	51_R	0.557	0.54
57_T	66_V	0.556	0.54
72_V	125_P	0.555	0.54
351_T	362_A	0.555	0.54
480_A	483_R	0.555	0.54
557_L	560_T	0.554	0.54
42_G	146_P	0.554	0.54
246_A	305_P	0.554	0.54
22_S	140_T	0.551	0.54
9_R	315_T	0.551	0.54
264_A	330_V	0.551	0.54
562_M	600_Q	0.551	0.54
545_R	551_E	0.550	0.53
121_E	124_E	0.548	0.53
358_A	371_R	0.548	0.53
379_S	445_R	0.548	0.53
369_T	376_G	0.548	0.53
108_E	179_L	0.548	0.53
560_T	564_P	0.548	0.53
307_P	465_R	0.547	0.53
280_S	285_E	0.547	0.53
55_V	114_A	0.546	0.53
106_A	141_L	0.546	0.53
505_A	590_D	0.546	0.53
342_P	345_A	0.546	0.53
394_D	467_E	0.546	0.53
201_F	204_Y	0.545	0.53
281_E	352_A	0.545	0.53
279_L	353_V	0.545	0.53
38_L	183_R	0.545	0.53
559_D	566_N	0.545	0.53
15_V	38_L	0.543	0.53
58_H	411_Q	0.543	0.53
553_N	556_Q	0.543	0.53
357_K	434_R	0.543	0.53
304_H	441_H	0.542	0.52
294_E	366_E	0.542	0.52
514_R	517_G	0.542	0.52
69_I	250_N	0.542	0.52
495_K	596_K	0.542	0.52
574_V	590_D	0.541	0.52
66_V	105_L	0.541	0.52
344_T	347_A	0.541	0.52
8_A	251_T	0.541	0.52
588_M	599_I	0.540	0.52
9_R	319_N	0.540	0.52
528_R	538_G	0.540	0.52
7_D	311_G	0.540	0.52
362_A	365_A	0.540	0.52
236_E	367_E	0.539	0.52
77_G	87_S	0.538	0.52
33_R	180_T	0.538	0.52
35_D	189_Q	0.538	0.52
368_L	448_I	0.538	0.52
535_Q	541_T	0.538	0.52
555_Q	559_D	0.538	0.52
532_V	541_T	0.538	0.52
488_T	588_M	0.538	0.52
221_G	235_S	0.538	0.52
128_D	269_V	0.538	0.52
117_R	133_G	0.537	0.52
130_Q	133_G	0.537	0.52
473_T	480_A	0.537	0.52
162_E	245_F	0.536	0.52
53_I	66_V	0.536	0.52
364_K	367_E	0.536	0.52
97_V	101_L	0.536	0.52
507_Q	523_M	0.536	0.52
552_M	560_T	0.536	0.52
374_A	381_P	0.535	0.51
67_E	120_F	0.535	0.51
266_T	293_R	0.535	0.51
499_E	574_V	0.534	0.51
514_R	542_Q	0.534	0.51
258_L	336_T	0.533	0.51
21_N	24_D	0.533	0.51
377_S	445_R	0.533	0.51
172_N	248_N	0.532	0.51
343_A	346_K	0.532	0.51
467_E	504_Y	0.532	0.51
164_R	167_E	0.531	0.51
546_F	553_N	0.531	0.51
448_I	494_M	0.531	0.51
266_T	270_N	0.531	0.51
23_I	324_G	0.531	0.51
288_T	366_E	0.531	0.51
205_L	297_T	0.530	0.51
44_V	179_L	0.530	0.51
558_W	565_E	0.530	0.51
435_L	455_I	0.528	0.51
446_H	473_T	0.528	0.51
378_T	437_R	0.527	0.50
579_A	601_E	0.527	0.50
31_C	50_G	0.527	0.50
395_A	465_R	0.526	0.50
7_D	319_N	0.526	0.50
409_A	557_L	0.526	0.50
206_N	213_H	0.526	0.50
578_A	581_D	0.525	0.50
250_N	315_T	0.525	0.50
407_G	413_R	0.525	0.50
42_G	104_R	0.524	0.50
27_L	303_K	0.524	0.50
8_A	160_T	0.523	0.50
16_Y	61_Y	0.523	0.50
47_T	108_E	0.523	0.50
289_G	295_G	0.523	0.50
109_V	142_I	0.522	0.50
245_F	281_E	0.521	0.50
307_P	395_A	0.521	0.50
292_I	356_A	0.520	0.49
398_F	483_R	0.520	0.49
389_S	393_E	0.520	0.49
245_F	250_N	0.519	0.49
433_H	438_I	0.519	0.49
438_I	473_T	0.518	0.49
7_D	593_E	0.517	0.49
278_L	284_G	0.517	0.49
169_A	195_E	0.517	0.49
344_T	352_A	0.517	0.49
362_A	369_T	0.517	0.49
360_K	364_K	0.517	0.49
238_V	363_K	0.517	0.49
399_V	403_D	0.516	0.49
437_R	598_F	0.516	0.49
215_D	222_E	0.516	0.49
253_E	318_G	0.515	0.49
39_H	180_T	0.515	0.49
71_T	125_P	0.515	0.49
18_V	249_I	0.513	0.49
32_D	344_T	0.513	0.49
487_L	584_F	0.513	0.49
202_V	231_A	0.512	0.48
223_D	328_R	0.512	0.48
468_N	504_Y	0.512	0.48
515_Y	537_N	0.511	0.48
523_M	527_D	0.510	0.48
55_V	182_E	0.510	0.48
58_H	70_L	0.509	0.48
207_E	597_Q	0.509	0.48
97_V	311_G	0.509	0.48
55_V	356_A	0.509	0.48
228_V	338_F	0.508	0.48
46_V	142_I	0.508	0.48
310_E	319_N	0.508	0.48
53_I	140_T	0.508	0.48
423_L	427_I	0.508	0.48
381_P	450_A	0.507	0.48
208_T	211_A	0.507	0.48
325_I	329_A	0.507	0.48
67_E	87_S	0.506	0.48
219_F	333_G	0.506	0.48
267_R	271_D	0.506	0.48
518_N	534_E	0.505	0.47
328_R	332_D	0.505	0.47
523_M	528_R	0.505	0.47
305_P	325_I	0.505	0.47
168_L	307_P	0.505	0.47
586_V	593_E	0.504	0.47
22_S	357_K	0.504	0.47
232_M	503_V	0.504	0.47
554_P	558_W	0.503	0.47
390_K	417_F	0.503	0.47
431_E	585_S	0.502	0.47
541_T	604_G	0.501	0.47
523_M	546_F	0.501	0.47
235_S	295_G	0.501	0.47
216_V	219_F	0.501	0.47
14_L	28_A	0.501	0.47
80_D	274_N	0.500	0.47
199_R	229_E	0.500	0.47
522_A	568_I	0.500	0.47
158_F	183_R	0.500	0.47

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
4i3hA	2	0.9034	100	0.069	Contact Map
4gfhA	2	0.9182	100	0.143	Contact Map
3nuhB	1	0.3077	100	0.542	Contact Map
3zkbA	5	0.5957	100	0.542	Contact Map
3k9fC	1	0.3568	100	0.557	Contact Map
2xkjE	2	0.3928	100	0.565	Contact Map
4urlA	1	0.5761	100	0.567	Contact Map
4wubA	2	0.5908	100	0.569	Contact Map
1zxmA	2	0.5385	100	0.574	Contact Map
3m4iA	2	0.3011	100	0.575	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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