Q9HR29 - HALSA - GREMLIN Contacts

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Q9HR29 - DNA gyrase subunit A

UniProt:	Q9HR29	Sequences: MSSESPDVPDDVADRVKNVRVDEEMEQSYIDYAMSVIAGRALPDVRDGLKPVHRRILYAMHESGVTSGSGHRKSSNIVGDTMGDYHPHGDSPIYDALVRMAQDFSMRYPLVDGQGNFGSVDGDPAAAMRYTEARMAPIAEELLTDIEKDTVAFQANYDDRLTEPAVLPSSFPNLLVNGSSGIAVGMSTNVPPHNLGEVIDATIHLIDTPDCTVLDLMEYVKGPDFPTAANIVGRADVKQAYQTGRGRVRMRAEYHVESNGRRDSIVITELPYQQNKSTLVERIADDVRDGKLEGITDLRDESDRNGVRIVIDLKQKANTDVVENRLLESHLEKTFSVINLALVDGEPKVLTLKELLAEYVSHRKEVVRRRSEHDLGEAEDRAHILDGRLTALENADEVVELIQDAEDRDAAKETLKSAFDFSQDQADHIVRMQLGSLTSMEAADIESEYEDVTARIERLEEILGSEQELLDVIKDELREIKTQYADERRTSFIEDTGTVADEDLIPEEDTVVVLSEGDYIKRVPAETFDAQHRGGKGIIGSDLKDGDRVSTVFTASTHDYLLCFTDQGQVYRLKVYQVPEMSRTARGTSAVNILDLDDGEEISAVVTADDLDFKADDEYLTMATRNGYVKRTSVGEFGNILSTGIIAIDLEDGDALADVEVTDGSHDVILGSEAGMAIRFDEGDVRAMGRNARGVRGMDLDAADRIAGVAAVESEDDRSLLTVTEFGYGKRTRVGEYRSQSRNGKGLVDIKTGDRNGDVVSVDAVGDDDSLVVMSADGQIIQMPVDEISTVGRNTKGVNIMAVGSGDEVAGVSVRAADQADGEE	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	824 (738)
Sequences:	5024 (2453)
Seq/√Len:	90.3

ECOLI - GYRA PARC
BACSU - GYRA PARC
HALSA - Q9HR29

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
82_M	93_I	5.692	1.00
379_E	460_E	5.546	1.00
196_G	485_A	4.571	1.00
207_D	474_K	4.484	1.00
200_D	481_K	4.151	1.00
204_H	211_C	4.128	1.00
672_S	698_M	3.976	1.00
71_H	112_D	3.499	1.00
204_H	219_Y	3.474	1.00
461_E	468_E	3.393	1.00
149_D	376_G	3.358	1.00
461_E	465_S	3.271	1.00
397_E	418_A	3.145	1.00
201_A	220_V	3.107	1.00
254_Y	327_L	3.035	1.00
458_R	468_E	3.035	1.00
120_V	307_V	3.026	1.00
205_L	356_L	2.954	1.00
625_R	655_A	2.954	1.00
154_Q	165_A	2.915	1.00
205_L	211_C	2.904	1.00
376_G	380_D	2.848	1.00
673_E	705_R	2.761	1.00
400_E	404_D	2.756	1.00
458_R	461_E	2.740	1.00
203_I	478_R	2.694	1.00
212_T	215_D	2.672	1.00
673_E	704_D	2.667	1.00
67_S	140_E	2.665	1.00
77_I	133_A	2.637	1.00
152_A	369_R	2.627	1.00
214_L	242_Q	2.614	1.00
667_D	679_R	2.611	1.00
196_G	487_E	2.610	1.00
390_T	421_F	2.572	1.00
651_E	693_R	2.541	1.00
76_N	84_D	2.511	1.00
171_F	176_V	2.491	1.00
368_R	372_E	2.487	1.00
216_L	352_L	2.482	1.00
213_V	351_T	2.467	1.00
479_E	483_Q	2.438	1.00
199_I	477_L	2.433	1.00
516_E	548_R	2.425	1.00
206_I	470_L	2.408	1.00
255_H	268_T	2.398	1.00
427_D	431_R	2.386	1.00
196_G	200_D	2.359	1.00
216_L	353_K	2.312	1.00
380_D	424_D	2.296	1.00
141_E	484_Y	2.283	1.00
108_Y	486_D	2.280	1.00
196_G	481_K	2.280	1.00
253_E	491_S	2.274	1.00
263_D	319_T	2.258	1.00
701_D	745_K	2.252	1.00
664_G	682_E	2.243	1.00
204_H	208_T	2.240	1.00
190_V	339_N	2.225	1.00
696_R	699_D	2.215	1.00
148_K	374_D	2.210	1.00
254_Y	265_I	2.192	1.00
678_I	744_G	2.188	1.00
211_C	215_D	2.187	1.00
566_D	655_A	2.187	1.00
623_A	709_V	2.173	1.00
678_I	740_Q	2.167	1.00
296_T	314_K	2.165	1.00
455_R	459_L	2.154	1.00
208_T	215_D	2.154	1.00
112_D	134_R	2.133	1.00
688_M	692_A	2.127	1.00
468_E	471_D	2.126	1.00
451_D	455_R	2.126	1.00
460_E	464_G	2.123	1.00
364_K	470_L	2.096	1.00
267_I	311_I	2.084	1.00
385_L	445_I	2.084	1.00
663_D	666_H	2.066	1.00
623_A	670_L	2.066	1.00
381_R	448_E	2.062	1.00
510_T	575_V	2.054	1.00
137_P	483_Q	2.045	1.00
377_E	380_D	2.044	1.00
737_Y	749_D	2.039	1.00
625_R	654_D	2.025	1.00
343_V	350_L	2.024	1.00
155_A	162_T	2.015	1.00
176_V	198_V	2.012	1.00
625_R	705_R	2.001	1.00
74_S	97_L	1.999	1.00
214_L	238_K	1.984	1.00
670_L	697_G	1.983	1.00
254_Y	323_E	1.966	1.00
198_V	220_V	1.965	1.00
662_T	682_E	1.957	1.00
155_A	159_D	1.939	1.00
471_D	475_D	1.938	1.00
447_S	451_D	1.928	1.00
371_S	459_L	1.922	1.00
412_K	427_D	1.920	1.00
367_V	473_I	1.914	1.00
724_T	750_I	1.912	1.00
238_K	242_Q	1.908	1.00
401_L	414_T	1.897	1.00
249_R	332_E	1.895	1.00
507_E	556_S	1.894	1.00
708_G	762_V	1.891	1.00
364_K	466_E	1.887	1.00
368_R	463_L	1.880	1.00
698_M	706_I	1.878	1.00
258_S	263_D	1.871	1.00
351_T	354_E	1.866	1.00
671_G	762_V	1.861	1.00
358_E	361_S	1.855	1.00
278_T	281_E	1.848	1.00
213_V	242_Q	1.841	1.00
45_V	358_E	1.840	1.00
462_I	472_V	1.837	1.00
555_A	559_D	1.835	1.00
348_K	354_E	1.825	1.00
203_I	474_K	1.824	1.00
443_A	447_S	1.820	1.00
91_S	95_D	1.818	1.00
567_Q	599_G	1.817	1.00
450_E	454_A	1.809	1.00
353_K	357_A	1.807	1.00
56_I	96_A	1.805	1.00
629_V	697_G	1.798	1.00
407_D	410_A	1.781	1.00
205_L	357_A	1.780	1.00
465_S	468_E	1.772	1.00
270_L	309_I	1.770	1.00
252_A	267_I	1.768	1.00
740_Q	744_G	1.755	1.00
211_C	219_Y	1.754	1.00
382_A	449_Y	1.743	1.00
469_L	472_V	1.741	1.00
92_P	96_A	1.721	1.00
205_L	360_V	1.721	1.00
372_E	376_G	1.713	1.00
213_V	353_K	1.702	1.00
190_V	355_L	1.701	1.00
390_T	394_N	1.697	1.00
565_T	602_I	1.694	1.00
76_N	80_D	1.672	1.00
72_R	76_N	1.663	1.00
684_D	741_S	1.655	1.00
222_G	237_V	1.648	1.00
171_F	480_I	1.636	1.00
621_T	668_V	1.634	1.00
446_E	450_E	1.630	1.00
374_D	459_L	1.628	1.00
202_T	360_V	1.627	1.00
357_A	361_S	1.621	1.00
97_L	133_A	1.614	1.00
215_D	218_E	1.612	1.00
621_T	629_V	1.609	1.00
409_D	413_E	1.603	1.00
404_D	414_T	1.590	1.00
408_R	435_G	1.588	1.00
141_E	144_T	1.575	1.00
413_E	417_S	1.570	1.00
441_E	444_D	1.568	1.00
152_A	165_A	1.566	1.00
670_L	706_I	1.552	1.00
344_D	361_S	1.545	1.00
628_Y	696_R	1.542	1.00
458_R	462_I	1.539	1.00
234_R	494_E	1.528	1.00
45_V	355_L	1.520	1.00
398_V	415_L	1.520	1.00
674_A	758_D	1.519	1.00
343_V	358_E	1.488	1.00
667_D	681_D	1.484	1.00
457_E	461_E	1.483	1.00
455_R	458_R	1.483	1.00
370_R	476_E	1.477	1.00
249_R	334_T	1.475	1.00
253_E	269_E	1.469	1.00
98_V	125_A	1.468	1.00
180_S	189_N	1.466	1.00
76_N	161_L	1.465	1.00
339_N	355_L	1.465	1.00
738_R	747_L	1.459	0.99
368_R	469_L	1.431	0.99
208_T	211_C	1.425	0.99
517_G	544_K	1.425	0.99
59_A	80_D	1.418	0.99
508_E	557_T	1.412	0.99
74_S	133_A	1.405	0.99
466_E	470_L	1.404	0.99
389_L	449_Y	1.402	0.99
449_Y	453_T	1.402	0.99
239_Q	242_Q	1.401	0.99
143_L	167_L	1.401	0.99
619_Y	687_A	1.398	0.99
301_E	310_V	1.396	0.99
556_S	559_D	1.395	0.99
566_D	600_E	1.378	0.99
623_A	706_I	1.376	0.99
566_D	601_E	1.375	0.99
100_M	106_M	1.372	0.99
719_S	731_R	1.370	0.99
202_T	356_L	1.369	0.99
76_N	83_G	1.356	0.99
486_D	489_R	1.350	0.99
235_A	239_Q	1.350	0.99
283_I	298_L	1.343	0.99
567_Q	597_D	1.341	0.99
412_K	423_Q	1.335	0.99
330_H	333_K	1.335	0.99
282_R	285_D	1.333	0.99
386_D	453_T	1.324	0.99
280_V	309_I	1.315	0.99
620_L	659_V	1.314	0.99
303_D	306_G	1.310	0.99
256_V	265_I	1.306	0.99
516_E	550_S	1.299	0.99
76_N	128_M	1.296	0.99
722_T	749_D	1.293	0.99
740_Q	747_L	1.293	0.99
59_A	82_M	1.290	0.99
295_I	311_I	1.290	0.99
749_D	759_V	1.287	0.99
454_A	458_R	1.281	0.99
189_N	336_S	1.280	0.99
262_R	296_T	1.276	0.99
457_E	460_E	1.273	0.99
478_R	482_T	1.269	0.99
283_I	311_I	1.268	0.99
107_R	486_D	1.268	0.99
230_N	253_E	1.265	0.99
401_L	418_A	1.264	0.99
394_N	421_F	1.252	0.98
84_D	161_L	1.252	0.98
241_Y	337_V	1.249	0.98
451_D	454_A	1.249	0.98
386_D	449_Y	1.248	0.98
241_Y	352_L	1.247	0.98
474_K	478_R	1.247	0.98
354_E	357_A	1.244	0.98
621_T	685_V	1.243	0.98
149_D	372_E	1.240	0.98
247_R	334_T	1.238	0.98
616_D	635_G	1.238	0.98
364_K	469_L	1.237	0.98
70_G	134_R	1.233	0.98
430_V	435_G	1.229	0.98
461_E	464_G	1.228	0.98
301_E	308_R	1.226	0.98
475_D	479_E	1.226	0.98
406_E	410_A	1.224	0.98
478_R	481_K	1.223	0.98
619_Y	631_R	1.219	0.98
279_L	309_I	1.215	0.98
213_V	216_L	1.215	0.98
397_E	400_E	1.211	0.98
299_R	312_D	1.207	0.98
389_L	446_E	1.202	0.98
317_A	322_V	1.200	0.98
264_S	312_D	1.197	0.98
280_V	298_L	1.197	0.98
572_R	640_I	1.196	0.98
80_D	84_D	1.195	0.98
667_D	739_S	1.194	0.98
622_M	656_L	1.194	0.98
649_D	692_A	1.193	0.98
748_V	751_K	1.184	0.98
205_L	353_K	1.181	0.98
257_E	308_R	1.179	0.98
462_I	468_E	1.175	0.98
631_R	687_A	1.174	0.98
213_V	217_M	1.170	0.98
384_I	428_H	1.157	0.97
475_D	478_R	1.156	0.97
564_F	659_V	1.155	0.97
22_D	26_E	1.155	0.97
361_S	364_K	1.154	0.97
38_A	342_L	1.153	0.97
230_N	493_I	1.150	0.97
562_L	570_V	1.149	0.97
204_H	215_D	1.147	0.97
58_Y	61_H	1.144	0.97
199_I	481_K	1.137	0.97
340_L	349_V	1.134	0.97
254_Y	267_I	1.128	0.97
20_R	23_E	1.128	0.97
252_A	331_L	1.127	0.97
359_Y	363_R	1.122	0.97
367_V	476_E	1.120	0.97
63_S	80_D	1.119	0.97
732_T	737_Y	1.115	0.97
672_S	704_D	1.114	0.97
29_Y	39_G	1.114	0.97
454_A	457_E	1.113	0.97
383_H	422_S	1.106	0.97
410_A	414_T	1.105	0.97
82_M	157_Y	1.104	0.97
256_V	323_E	1.099	0.96
628_Y	693_R	1.099	0.96
752_T	755_R	1.092	0.96
502_E	574_K	1.090	0.96
569_Q	597_D	1.085	0.96
725_E	758_D	1.081	0.96
621_T	662_T	1.081	0.96
27_Q	31_D	1.081	0.96
257_E	266_V	1.078	0.96
222_G	492_F	1.076	0.96
507_E	557_T	1.076	0.96
699_D	745_K	1.075	0.96
388_R	445_I	1.073	0.96
237_V	248_V	1.069	0.96
442_A	446_E	1.069	0.96
555_A	575_V	1.069	0.96
230_N	250_M	1.068	0.96
57_L	143_L	1.067	0.96
666_H	713_E	1.067	0.96
72_R	160_R	1.065	0.96
582_S	585_A	1.063	0.96
250_M	490_T	1.061	0.96
385_L	452_V	1.060	0.96
538_I	583_R	1.060	0.96
250_M	333_K	1.060	0.96
248_V	337_V	1.059	0.96
382_A	456_I	1.058	0.96
674_A	704_D	1.055	0.95
240_A	337_V	1.054	0.95
372_E	379_E	1.053	0.95
626_N	653_G	1.049	0.95
147_E	374_D	1.046	0.95
192_P	226_P	1.045	0.95
669_I	677_A	1.043	0.95
229_A	252_A	1.039	0.95
142_L	169_S	1.033	0.95
367_V	469_L	1.032	0.95
67_S	137_P	1.029	0.95
170_S	363_R	1.028	0.95
581_M	585_A	1.028	0.95
416_K	426_A	1.025	0.95
389_L	445_I	1.023	0.95
341_A	355_L	1.023	0.95
623_A	697_G	1.023	0.95
660_E	709_V	1.022	0.95
53_H	105_S	1.018	0.95
234_R	237_V	1.017	0.94
411_A	438_T	1.016	0.94
313_L	317_A	1.015	0.94
395_A	403_Q	1.012	0.94
414_T	417_S	1.010	0.94
82_M	91_S	1.008	0.94
633_S	687_A	1.008	0.94
371_S	462_I	1.008	0.94
111_V	133_A	1.002	0.94
66_T	69_S	1.000	0.94
732_T	736_E	1.000	0.94
191_P	339_N	0.996	0.94
467_Q	475_D	0.995	0.94
343_V	348_K	0.990	0.94
176_V	195_L	0.989	0.94
171_F	199_I	0.988	0.94
59_A	93_I	0.987	0.94
231_I	490_T	0.986	0.94
381_R	385_L	0.983	0.93
622_M	647_A	0.982	0.93
45_V	350_L	0.981	0.93
633_S	636_E	0.980	0.93
149_D	369_R	0.977	0.93
282_R	330_H	0.977	0.93
199_I	202_T	0.976	0.93
405_A	414_T	0.976	0.93
373_H	377_E	0.976	0.93
628_Y	651_E	0.975	0.93
637_F	647_A	0.972	0.93
632_T	637_F	0.970	0.93
458_R	465_S	0.966	0.93
410_A	413_E	0.965	0.93
217_M	242_Q	0.964	0.93
543_L	549_V	0.963	0.93
200_D	203_I	0.963	0.93
81_T	93_I	0.962	0.93
375_L	456_I	0.960	0.93
722_T	737_Y	0.959	0.93
673_E	758_D	0.957	0.92
394_N	397_E	0.957	0.92
230_N	491_S	0.957	0.92
203_I	481_K	0.956	0.92
479_E	482_T	0.954	0.92
228_A	253_E	0.950	0.92
236_D	239_Q	0.950	0.92
138_I	173_N	0.949	0.92
313_L	322_V	0.949	0.92
200_D	478_R	0.948	0.92
658_D	709_V	0.945	0.92
649_D	691_N	0.944	0.92
468_E	472_V	0.944	0.92
356_L	360_V	0.944	0.92
672_S	706_I	0.939	0.92
267_I	331_L	0.936	0.92
376_G	379_E	0.936	0.92
220_V	352_L	0.936	0.92
699_D	743_N	0.934	0.92
204_H	218_E	0.934	0.92
382_A	453_T	0.932	0.91
65_V	77_I	0.931	0.91
467_Q	471_D	0.930	0.91
557_T	575_V	0.927	0.91
401_L	426_A	0.926	0.91
450_E	453_T	0.925	0.91
202_T	477_L	0.918	0.91
108_Y	138_I	0.916	0.91
63_S	76_N	0.915	0.91
110_L	142_L	0.914	0.91
750_I	755_R	0.911	0.91
564_F	570_V	0.911	0.91
512_V	575_V	0.910	0.90
63_S	77_I	0.908	0.90
174_L	341_A	0.907	0.90
688_M	693_R	0.906	0.90
622_M	659_V	0.904	0.90
514_L	605_V	0.902	0.90
458_R	475_D	0.901	0.90
676_M	745_K	0.895	0.90
428_H	432_M	0.892	0.90
632_T	636_E	0.891	0.90
563_C	605_V	0.889	0.89
234_R	238_K	0.886	0.89
72_R	84_D	0.884	0.89
626_N	654_D	0.881	0.89
207_D	478_R	0.880	0.89
567_Q	600_E	0.877	0.89
80_D	157_Y	0.876	0.89
423_Q	427_D	0.875	0.89
303_D	307_V	0.875	0.89
392_L	442_A	0.875	0.89
231_I	250_M	0.871	0.88
208_T	219_Y	0.870	0.88
510_T	557_T	0.870	0.88
251_R	332_E	0.869	0.88
390_T	420_D	0.869	0.88
208_T	212_T	0.867	0.88
68_G	140_E	0.865	0.88
397_E	419_F	0.865	0.88
458_R	472_V	0.865	0.88
121_D	276_K	0.863	0.88
374_D	455_R	0.863	0.88
680_F	685_V	0.860	0.88
608_A	611_L	0.859	0.88
135_M	139_A	0.858	0.88
274_Q	279_L	0.858	0.88
211_C	360_V	0.857	0.88
144_T	363_R	0.856	0.88
416_K	423_Q	0.852	0.87
386_D	422_S	0.852	0.87
462_I	469_L	0.850	0.87
398_V	419_F	0.849	0.87
464_G	468_E	0.844	0.87
196_G	482_T	0.843	0.87
618_E	661_V	0.842	0.87
206_I	474_K	0.837	0.86
59_A	85_Y	0.836	0.86
231_I	248_V	0.835	0.86
700_L	704_D	0.835	0.86
634_V	661_V	0.833	0.86
233_G	237_V	0.831	0.86
471_D	482_T	0.831	0.86
323_E	327_L	0.830	0.86
34_M	38_A	0.826	0.86
676_M	701_D	0.825	0.86
24_E	28_S	0.824	0.86
205_L	209_P	0.822	0.85
59_A	63_S	0.821	0.85
447_S	450_E	0.820	0.85
480_I	484_Y	0.819	0.85
138_I	171_F	0.818	0.85
149_D	380_D	0.818	0.85
624_T	648_I	0.815	0.85
350_L	358_E	0.814	0.85
512_V	578_V	0.812	0.85
108_Y	485_A	0.809	0.84
432_M	436_S	0.809	0.84
266_V	310_V	0.809	0.84
259_N	264_S	0.808	0.84
280_V	284_A	0.808	0.84
398_V	421_F	0.807	0.84
371_S	463_L	0.807	0.84
235_A	238_K	0.806	0.84
559_D	609_D	0.805	0.84
453_T	457_E	0.802	0.84
741_S	744_G	0.801	0.84
670_L	698_M	0.800	0.84
195_L	480_I	0.800	0.84
265_I	323_E	0.800	0.84
401_L	419_F	0.799	0.84
110_L	173_N	0.799	0.84
203_I	207_D	0.798	0.84
392_L	445_I	0.796	0.83
375_L	460_E	0.793	0.83
66_T	140_E	0.792	0.83
382_A	386_D	0.792	0.83
46_R	166_V	0.791	0.83
254_Y	319_T	0.791	0.83
648_I	656_L	0.790	0.83
39_G	179_S	0.788	0.83
108_Y	487_E	0.788	0.83
623_A	629_V	0.787	0.83
78_V	128_M	0.787	0.83
671_G	749_D	0.787	0.83
444_D	447_S	0.786	0.83
202_T	359_Y	0.786	0.83
281_E	285_D	0.786	0.83
170_S	480_I	0.785	0.83
555_A	607_T	0.785	0.83
621_T	697_G	0.784	0.83
514_L	553_F	0.783	0.82
63_S	157_Y	0.782	0.82
394_N	401_L	0.781	0.82
750_I	759_V	0.781	0.82
220_V	351_T	0.781	0.82
200_D	485_A	0.780	0.82
77_I	82_M	0.780	0.82
233_G	236_D	0.779	0.82
176_V	199_I	0.779	0.82
170_S	479_E	0.777	0.82
433_Q	436_S	0.776	0.82
144_T	170_S	0.775	0.82
157_Y	160_R	0.774	0.82
553_F	605_V	0.774	0.82
596_L	602_I	0.772	0.82
338_I	349_V	0.772	0.82
198_V	201_A	0.770	0.81
620_L	634_V	0.766	0.81
509_D	556_S	0.766	0.81
601_E	655_A	0.766	0.81
71_H	114_Q	0.766	0.81
200_D	221_K	0.765	0.81
393_E	442_A	0.764	0.81
565_T	600_E	0.763	0.81
63_S	84_D	0.762	0.81
221_K	234_R	0.762	0.81
565_T	571_Y	0.762	0.81
637_F	688_M	0.762	0.81
70_G	160_R	0.761	0.81
237_V	240_A	0.761	0.81
408_R	427_D	0.761	0.81
242_Q	353_K	0.759	0.80
213_V	219_Y	0.759	0.80
560_Y	572_R	0.758	0.80
42_L	341_A	0.758	0.80
174_L	355_L	0.758	0.80
402_I	434_L	0.754	0.80
371_S	472_V	0.754	0.80
298_L	311_I	0.752	0.80
684_D	740_Q	0.752	0.80
507_E	558_H	0.751	0.80
590_A	602_I	0.751	0.80
72_R	161_L	0.750	0.80
145_D	148_K	0.750	0.80
247_R	336_S	0.749	0.80
656_L	659_V	0.749	0.80
720_L	734_V	0.748	0.80
285_D	289_D	0.748	0.80
519_Y	589_S	0.747	0.79
461_E	466_E	0.747	0.79
276_K	300_D	0.745	0.79
212_T	353_K	0.744	0.79
350_L	354_E	0.742	0.79
138_I	195_L	0.742	0.79
122_G	275_N	0.742	0.79
369_R	372_E	0.742	0.79
510_T	522_R	0.742	0.79
388_R	440_M	0.741	0.79
120_V	270_L	0.739	0.79
371_S	455_R	0.739	0.79
676_M	740_Q	0.738	0.79
202_T	473_I	0.738	0.79
631_R	682_E	0.738	0.79
626_N	705_R	0.738	0.79
156_N	160_R	0.737	0.79
681_D	739_S	0.737	0.79
114_Q	588_T	0.736	0.78
207_D	467_Q	0.735	0.78
109_P	136_A	0.734	0.78
387_G	422_S	0.733	0.78
641_L	645_I	0.732	0.78
481_K	485_A	0.731	0.78
200_D	219_Y	0.731	0.78
660_E	711_A	0.731	0.78
219_Y	353_K	0.730	0.78
608_A	634_V	0.729	0.78
621_T	709_V	0.729	0.78
348_K	358_E	0.729	0.78
292_L	325_R	0.728	0.78
201_A	216_L	0.728	0.78
476_E	479_E	0.727	0.78
199_I	480_I	0.725	0.77
365_E	372_E	0.724	0.77
278_T	282_R	0.724	0.77
401_L	435_G	0.723	0.77
624_T	654_D	0.722	0.77
512_V	553_F	0.722	0.77
248_V	334_T	0.721	0.77
106_M	109_P	0.721	0.77
80_D	83_G	0.720	0.77
387_G	421_F	0.720	0.77
465_S	471_D	0.718	0.77
604_A	659_V	0.718	0.77
391_A	395_A	0.718	0.77
669_I	720_L	0.717	0.77
406_E	439_S	0.717	0.77
511_V	525_A	0.717	0.77
77_I	83_G	0.717	0.77
195_L	199_I	0.716	0.76
400_E	403_Q	0.715	0.76
217_M	353_K	0.714	0.76
145_D	150_T	0.713	0.76
618_E	663_D	0.713	0.76
571_Y	644_G	0.712	0.76
82_M	96_A	0.712	0.76
665_S	681_D	0.710	0.76
396_D	403_Q	0.710	0.76
724_T	759_V	0.710	0.76
58_Y	62_E	0.710	0.76
194_N	485_A	0.709	0.76
200_D	482_T	0.708	0.76
383_H	424_D	0.708	0.76
375_L	379_E	0.708	0.76
65_V	82_M	0.708	0.76
263_D	313_L	0.708	0.76
64_G	69_S	0.708	0.76
156_N	161_L	0.708	0.76
388_R	432_M	0.707	0.76
213_V	352_L	0.707	0.76
619_Y	664_G	0.707	0.76
514_L	551_T	0.707	0.76
563_C	594_L	0.704	0.75
623_A	658_D	0.701	0.75
673_E	707_A	0.701	0.75
229_A	253_E	0.701	0.75
252_A	327_L	0.701	0.75
62_E	85_Y	0.700	0.75
397_E	401_L	0.700	0.75
128_M	161_L	0.699	0.75
78_V	90_D	0.699	0.75
725_E	757_G	0.694	0.74
30_I	157_Y	0.693	0.74
107_R	489_R	0.693	0.74
74_S	82_M	0.693	0.74
508_E	524_P	0.693	0.74
677_A	740_Q	0.692	0.74
411_A	430_V	0.691	0.74
717_D	735_G	0.691	0.74
407_D	413_E	0.689	0.74
337_V	355_L	0.689	0.74
430_V	436_S	0.688	0.74
649_D	693_R	0.688	0.74
63_S	72_R	0.688	0.74
395_A	398_V	0.684	0.73
718_R	722_T	0.684	0.73
95_D	99_R	0.683	0.73
461_E	469_L	0.683	0.73
136_A	139_A	0.683	0.73
378_A	455_R	0.683	0.73
522_R	580_E	0.682	0.73
523_V	527_T	0.682	0.73
388_R	391_A	0.681	0.73
544_K	586_R	0.681	0.73
520_I	590_A	0.680	0.73
391_A	398_V	0.679	0.73
83_G	161_L	0.678	0.73
712_V	734_V	0.677	0.72
738_R	741_S	0.677	0.72
267_I	309_I	0.677	0.72
458_R	471_D	0.677	0.72
166_V	362_H	0.675	0.72
35_S	39_G	0.674	0.72
252_A	270_L	0.674	0.72
146_I	153_F	0.674	0.72
217_M	220_V	0.673	0.72
42_L	179_S	0.672	0.72
254_Y	268_T	0.672	0.72
379_E	456_I	0.671	0.72
507_E	609_D	0.671	0.72
713_E	716_D	0.670	0.72
69_S	134_R	0.669	0.72
173_N	176_V	0.668	0.71
138_I	141_E	0.668	0.71
519_Y	592_N	0.668	0.71
367_V	370_R	0.667	0.71
722_T	759_V	0.667	0.71
225_F	335_F	0.665	0.71
259_N	262_R	0.664	0.71
511_V	554_T	0.664	0.71
357_A	360_V	0.664	0.71
472_V	475_D	0.664	0.71
135_M	157_Y	0.663	0.71
703_A	733_R	0.663	0.71
36_V	184_V	0.660	0.70
65_V	72_R	0.660	0.70
256_V	319_T	0.660	0.70
276_K	302_S	0.659	0.70
225_F	248_V	0.658	0.70
559_D	607_T	0.658	0.70
68_G	134_R	0.656	0.70
513_V	523_V	0.656	0.70
284_A	298_L	0.656	0.70
443_A	446_E	0.655	0.70
549_V	552_V	0.654	0.70
262_R	314_K	0.654	0.70
141_E	483_Q	0.653	0.70
284_A	297_D	0.652	0.70
212_T	242_Q	0.651	0.69
515_S	547_D	0.651	0.69
39_G	342_L	0.650	0.69
752_T	759_V	0.650	0.69
752_T	757_G	0.649	0.69
385_L	449_Y	0.649	0.69
524_P	527_T	0.648	0.69
679_R	739_S	0.648	0.69
77_I	81_T	0.647	0.69
409_D	412_K	0.646	0.69
275_N	279_L	0.646	0.69
405_A	410_A	0.645	0.69
257_E	267_I	0.645	0.69
72_R	80_D	0.645	0.69
344_D	350_L	0.643	0.69
388_R	428_H	0.643	0.69
31_D	38_A	0.643	0.69
200_D	487_E	0.643	0.69
400_E	418_A	0.642	0.68
461_E	471_D	0.642	0.68
603_S	622_M	0.642	0.68
726_F	757_G	0.641	0.68
74_S	128_M	0.641	0.68
204_H	216_L	0.640	0.68
247_R	250_M	0.640	0.68
566_D	603_S	0.638	0.68
344_D	348_K	0.638	0.68
76_N	160_R	0.638	0.68
250_M	335_F	0.637	0.68
321_V	503_D	0.637	0.68
500_A	577_Q	0.636	0.68
299_R	308_R	0.636	0.68
627_G	698_M	0.635	0.68
44_D	166_V	0.635	0.68
217_M	238_K	0.635	0.68
507_E	559_D	0.634	0.67
257_E	301_E	0.634	0.67
359_Y	538_I	0.634	0.67
657_A	706_I	0.634	0.67
378_A	456_I	0.633	0.67
399_V	402_I	0.632	0.67
720_L	762_V	0.632	0.67
154_Q	163_E	0.632	0.67
304_R	522_R	0.632	0.67
713_E	718_R	0.632	0.67
671_G	720_L	0.631	0.67
71_H	134_R	0.630	0.67
276_K	307_V	0.630	0.67
169_S	359_Y	0.629	0.67
439_S	442_A	0.629	0.67
231_I	492_F	0.628	0.67
336_S	340_L	0.628	0.67
573_L	594_L	0.628	0.67
214_L	217_M	0.627	0.67
713_E	717_D	0.626	0.66
157_Y	247_R	0.626	0.66
408_R	412_K	0.623	0.66
256_V	313_L	0.623	0.66
101_A	113_G	0.620	0.66
572_R	638_G	0.620	0.66
553_F	561_L	0.619	0.66
394_N	418_A	0.619	0.66
733_R	737_Y	0.619	0.66
753_G	757_G	0.619	0.66
69_S	72_R	0.618	0.65
65_V	134_R	0.617	0.65
637_F	692_A	0.617	0.65
101_A	111_V	0.617	0.65
196_G	486_D	0.616	0.65
257_E	264_S	0.616	0.65
744_G	747_L	0.616	0.65
74_S	161_L	0.615	0.65
236_D	240_A	0.615	0.65
399_V	403_Q	0.615	0.65
266_V	308_R	0.613	0.65
82_M	90_D	0.612	0.65
563_C	590_A	0.612	0.65
39_G	95_D	0.612	0.65
252_A	309_I	0.612	0.65
210_D	215_D	0.612	0.65
201_A	211_C	0.611	0.65
232_V	493_I	0.611	0.65
646_I	649_D	0.611	0.65
76_N	157_Y	0.610	0.64
358_E	362_H	0.610	0.64
82_M	128_M	0.610	0.64
433_Q	438_T	0.610	0.64
412_K	416_K	0.609	0.64
665_S	683_G	0.608	0.64
707_A	759_V	0.608	0.64
61_H	146_I	0.607	0.64
406_E	443_A	0.607	0.64
100_M	191_P	0.607	0.64
190_V	356_L	0.607	0.64
26_E	30_I	0.607	0.64
296_T	317_A	0.606	0.64
170_S	476_E	0.606	0.64
719_S	722_T	0.604	0.64
52_V	95_D	0.604	0.64
427_D	435_G	0.604	0.64
564_F	647_A	0.603	0.64
60_M	111_V	0.602	0.63
231_I	237_V	0.601	0.63
392_L	441_E	0.600	0.63
505_I	576_Y	0.599	0.63
417_S	420_D	0.599	0.63
202_T	469_L	0.598	0.63
414_T	426_A	0.598	0.63
385_L	448_E	0.598	0.63
270_L	277_S	0.597	0.63
412_K	430_V	0.596	0.63
63_S	128_M	0.596	0.63
393_E	403_Q	0.595	0.63
722_T	732_T	0.595	0.63
207_D	482_T	0.595	0.63
232_V	495_D	0.595	0.63
666_H	682_E	0.595	0.63
742_R	746_G	0.595	0.63
567_Q	655_A	0.594	0.62
517_G	546_G	0.594	0.62
619_Y	633_S	0.593	0.62
663_D	682_E	0.593	0.62
251_R	327_L	0.592	0.62
362_H	366_V	0.592	0.62
392_L	438_T	0.592	0.62
570_V	640_I	0.591	0.62
672_S	676_M	0.591	0.62
368_R	466_E	0.591	0.62
389_L	442_A	0.590	0.62
620_L	661_V	0.590	0.62
211_C	357_A	0.589	0.62
218_E	234_R	0.589	0.62
100_M	105_S	0.589	0.62
277_S	280_V	0.587	0.62
229_A	250_M	0.587	0.62
61_H	143_L	0.587	0.62
394_N	398_V	0.587	0.62
247_R	338_I	0.587	0.62
374_D	458_R	0.586	0.61
416_K	420_D	0.586	0.61
677_A	747_L	0.586	0.61
531_Q	537_G	0.586	0.61
139_A	142_L	0.586	0.61
360_V	474_K	0.586	0.61
52_V	96_A	0.586	0.61
717_D	733_R	0.586	0.61
448_E	452_V	0.586	0.61
561_L	575_V	0.585	0.61
606_V	620_L	0.585	0.61
252_A	279_L	0.585	0.61
228_A	270_L	0.584	0.61
145_D	370_R	0.583	0.61
283_I	329_S	0.583	0.61
506_P	558_H	0.582	0.61
59_A	72_R	0.582	0.61
431_R	435_G	0.581	0.61
748_V	752_T	0.580	0.61
719_S	733_R	0.580	0.61
465_S	469_L	0.579	0.60
430_V	445_I	0.579	0.60
610_D	616_D	0.579	0.60
660_E	710_A	0.578	0.60
128_M	158_D	0.578	0.60
611_L	634_V	0.578	0.60
45_V	341_A	0.577	0.60
481_K	487_E	0.576	0.60
341_A	351_T	0.576	0.60
68_G	114_Q	0.575	0.60
145_D	367_V	0.575	0.60
171_F	202_T	0.575	0.60
646_I	691_N	0.574	0.60
242_Q	351_T	0.574	0.60
95_D	125_A	0.574	0.60
59_A	81_T	0.573	0.60
35_S	38_A	0.573	0.60
56_I	106_M	0.572	0.60
637_F	691_N	0.572	0.60
390_T	419_F	0.571	0.59
384_I	424_D	0.570	0.59
70_G	76_N	0.570	0.59
739_S	744_G	0.570	0.59
669_I	679_R	0.570	0.59
752_T	758_D	0.569	0.59
415_L	420_D	0.569	0.59
21_V	31_D	0.568	0.59
265_I	322_V	0.568	0.59
91_S	97_L	0.567	0.59
467_Q	470_L	0.567	0.59
432_M	439_S	0.567	0.59
735_G	739_S	0.566	0.59
461_E	467_Q	0.566	0.59
53_H	93_I	0.565	0.59
640_I	643_T	0.565	0.59
668_V	682_E	0.565	0.59
207_D	471_D	0.565	0.59
553_F	607_T	0.565	0.59
674_A	703_A	0.564	0.58
334_T	337_V	0.564	0.58
393_E	439_S	0.563	0.58
180_S	335_F	0.563	0.58
213_V	354_E	0.563	0.58
256_V	263_D	0.562	0.58
122_G	125_A	0.562	0.58
273_Q	430_V	0.562	0.58
416_K	419_F	0.562	0.58
341_A	350_L	0.562	0.58
450_E	457_E	0.562	0.58
287_V	297_D	0.561	0.58
682_E	685_V	0.561	0.58
626_N	703_A	0.560	0.58
412_K	426_A	0.560	0.58
108_Y	176_V	0.560	0.58
53_H	95_D	0.560	0.58
119_S	123_D	0.559	0.58
382_A	452_V	0.559	0.58
290_G	293_E	0.558	0.58
189_N	335_F	0.558	0.58
205_L	215_D	0.558	0.58
65_V	70_G	0.558	0.58
128_M	157_Y	0.557	0.58
324_N	503_D	0.557	0.58
252_A	333_K	0.556	0.57
438_T	443_A	0.556	0.57
671_G	677_A	0.556	0.57
293_E	314_K	0.555	0.57
551_T	605_V	0.555	0.57
722_T	725_E	0.555	0.57
61_H	135_M	0.555	0.57
143_L	146_I	0.555	0.57
215_D	219_Y	0.555	0.57
398_V	434_L	0.555	0.57
174_L	190_V	0.554	0.57
62_E	80_D	0.554	0.57
728_Y	757_G	0.554	0.57
240_A	352_L	0.553	0.57
724_T	728_Y	0.553	0.57
142_L	171_F	0.553	0.57
279_L	331_L	0.553	0.57
393_E	419_F	0.553	0.57
180_S	273_Q	0.552	0.57
679_R	712_V	0.552	0.57
21_V	25_M	0.551	0.57
360_V	470_L	0.550	0.57
262_R	312_D	0.550	0.57
84_D	160_R	0.549	0.56
723_V	727_G	0.549	0.56
72_R	128_M	0.549	0.56
448_E	451_D	0.548	0.56
63_S	82_M	0.548	0.56
29_Y	338_I	0.548	0.56
463_L	469_L	0.547	0.56
123_D	276_K	0.547	0.56
201_A	204_H	0.546	0.56
280_V	300_D	0.545	0.56
202_T	205_L	0.544	0.56
710_A	720_L	0.544	0.56
401_L	404_D	0.544	0.56
245_R	338_I	0.543	0.56
149_D	162_T	0.543	0.56
35_S	117_F	0.543	0.56
231_I	337_V	0.543	0.56
261_R	315_Q	0.543	0.56
59_A	128_M	0.541	0.55
206_I	360_V	0.541	0.55
217_M	221_K	0.541	0.55
29_Y	363_R	0.540	0.55
458_R	464_G	0.540	0.55
572_R	639_N	0.539	0.55
471_D	474_K	0.539	0.55
91_S	125_A	0.539	0.55
408_R	431_R	0.539	0.55
201_A	356_L	0.538	0.55
677_A	749_D	0.536	0.55
671_G	708_G	0.536	0.55
519_Y	587_G	0.536	0.55
759_V	762_V	0.535	0.55
277_S	284_A	0.535	0.55
564_F	656_L	0.535	0.55
589_S	750_I	0.535	0.55
733_R	736_E	0.535	0.55
239_Q	243_T	0.535	0.55
603_S	650_L	0.535	0.55
65_V	97_L	0.534	0.54
237_V	241_Y	0.533	0.54
401_L	433_Q	0.533	0.54
563_C	602_I	0.532	0.54
298_L	309_I	0.532	0.54
203_I	477_L	0.531	0.54
413_E	416_K	0.531	0.54
378_A	459_L	0.531	0.54
702_A	705_R	0.530	0.54
35_S	342_L	0.530	0.54
176_V	196_G	0.530	0.54
233_G	240_A	0.529	0.54
674_A	701_D	0.529	0.54
29_Y	114_Q	0.529	0.54
279_L	283_I	0.529	0.54
658_D	670_L	0.528	0.54
672_S	700_L	0.527	0.53
668_V	711_A	0.527	0.53
636_E	687_A	0.527	0.53
350_L	355_L	0.527	0.53
169_S	363_R	0.526	0.53
210_D	353_K	0.526	0.53
93_I	292_L	0.526	0.53
214_L	218_E	0.526	0.53
734_V	737_Y	0.525	0.53
611_L	635_G	0.524	0.53
406_E	438_T	0.524	0.53
649_D	702_A	0.524	0.53
280_V	303_D	0.524	0.53
407_D	438_T	0.524	0.53
439_S	443_A	0.524	0.53
522_R	557_T	0.524	0.53
499_V	503_D	0.524	0.53
528_F	554_T	0.523	0.53
364_K	368_R	0.522	0.53
622_M	637_F	0.522	0.53
395_A	452_V	0.522	0.53
245_R	336_S	0.521	0.53
623_A	668_V	0.519	0.52
600_E	650_L	0.519	0.52
721_L	729_G	0.519	0.52
215_D	478_R	0.519	0.52
396_D	402_I	0.518	0.52
283_I	326_L	0.517	0.52
508_E	522_R	0.517	0.52
623_A	660_E	0.516	0.52
105_S	281_E	0.516	0.52
232_V	497_G	0.516	0.52
222_G	672_S	0.516	0.52
71_H	124_P	0.516	0.52
142_L	167_L	0.515	0.52
292_L	331_L	0.515	0.52
199_I	469_L	0.515	0.52
321_V	505_I	0.515	0.52
379_E	382_A	0.515	0.52
257_E	312_D	0.514	0.52
513_V	528_F	0.514	0.52
114_Q	140_E	0.513	0.52
53_H	104_F	0.513	0.52
313_L	319_T	0.512	0.51
274_Q	330_H	0.512	0.51
521_K	587_G	0.512	0.51
298_L	301_E	0.512	0.51
323_E	332_E	0.511	0.51
617_D	633_S	0.511	0.51
758_D	761_S	0.511	0.51
384_I	432_M	0.511	0.51
400_E	414_T	0.511	0.51
197_E	217_M	0.511	0.51
671_G	750_I	0.510	0.51
367_V	472_V	0.510	0.51
186_M	340_L	0.510	0.51
676_M	748_V	0.510	0.51
58_Y	146_I	0.509	0.51
25_M	341_A	0.509	0.51
629_V	670_L	0.509	0.51
121_D	302_S	0.509	0.51
92_P	104_F	0.508	0.51
141_E	147_E	0.508	0.51
292_L	329_S	0.508	0.51
24_E	35_S	0.508	0.51
560_Y	574_K	0.508	0.51
595_D	643_T	0.508	0.51
62_E	161_L	0.508	0.51
426_A	702_A	0.507	0.51
49_L	80_D	0.507	0.51
133_A	136_A	0.506	0.51
379_E	386_D	0.506	0.51
373_H	424_D	0.506	0.51
146_I	163_E	0.506	0.51
723_V	729_G	0.505	0.50
138_I	484_Y	0.505	0.50
702_A	754_D	0.505	0.50
176_V	480_I	0.505	0.50
390_T	446_E	0.505	0.50
63_S	66_T	0.505	0.50
511_V	528_F	0.504	0.50
680_F	684_D	0.504	0.50
171_F	363_R	0.504	0.50
706_I	717_D	0.503	0.50
666_H	711_A	0.503	0.50
724_T	727_G	0.502	0.50
258_S	261_R	0.502	0.50
266_V	309_I	0.502	0.50
737_Y	740_Q	0.501	0.50
198_V	355_L	0.501	0.50
419_F	422_S	0.501	0.50
342_L	345_G	0.501	0.50
464_G	471_D	0.501	0.50
647_A	690_R	0.501	0.50
673_E	703_A	0.500	0.50
77_I	93_I	0.500	0.50
456_I	460_E	0.500	0.50
743_N	746_G	0.500	0.50

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
1zvuA	2	0.8083	100	0.208	Contact Map
4i3hA	2	0.591	100	0.337	Contact Map
2inrA	2	0.5352	100	0.338	Contact Map
2novA	2	0.5473	100	0.341	Contact Map
2xcsB	2	0.591	100	0.343	Contact Map
2xkjE	2	0.585	100	0.35	Contact Map
3ilwA	2	0.5546	100	0.355	Contact Map
4ckkA	2	0.5461	100	0.365	Contact Map
4gfhA	2	0.5595	100	0.467	Contact Map
3l4jA	1	0.5558	100	0.485	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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