Q9HR16 - HALSA - GREMLIN Contacts

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Q9HR16 - Proline permease

UniProt:	Q9HR16	Sequences: MDSVGDYVIGGRDVGPVVTGFSERASEMSGWLTLGVPGDAYTTGIMAFYNGVGMIPADLAAWAGLAKRLRKYSEIVRAVTLPTFFATRLNDDTGVVKAVSSFVLIVFEGSYVGAQIVAAGTLLRVLTGVDMWVGIVAGGVIVVGYTMLGGYFAVAWSDYFQGAIILAAFAILPIIAYATWGLPFADLAAMDNGASLTSITGGATGWAALFGIISYAAVGLGIPGNPHIMVRFMGIDRVRNVRTAAVVAQLFMFVAYIGAALVGLYALTQFGGLENTDNAMPLVTLELLPSAVAGVVLAAALAAMMSSADSQLLVATSAVVEDVYHGFLNEQATEAQLVRYSRYVTLAIGFASIGFAYVARNTPIYELVLNYAWGGLGAALGPLLIAVLWWRRVTAAGAVASMVTGTATMILWTQWPTILGPETVNSFHPAVSGMLTVYGLFPAFVVSAVVLVVVSLLTTPPDQDDVSEAFDMMHRPLAAITDDDGDGSEYATDGGRPDPAPITEHDSIRSHVADTDYWTDDD	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	522 (441)
Sequences:	11530 (7107)
Seq/√Len:	338.4

ECOLI - ACTP PUTP YIDK PANF
BACSU - YWCA OPUE YCGO YHJB YODF
HALSA - Q9HR16 Q9HP63
SULSO - Q7LX83 Q97VX6

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
404_T	450_V	5.955	1.00
333_T	336_Q	4.230	1.00
393_V	451_L	3.951	1.00
237_R	240_N	3.950	1.00
329_N	336_Q	3.541	1.00
404_T	446_V	3.327	1.00
143_V	349_G	3.305	1.00
452_V	456_L	3.271	1.00
174_I	178_A	3.160	1.00
324_Y	332_A	3.145	1.00
401_S	451_L	3.130	1.00
394_T	458_T	3.069	1.00
185_A	188_A	3.050	1.00
176_A	265_Y	2.984	1.00
450_V	454_V	2.983	1.00
454_V	458_T	2.982	1.00
335_A	339_R	2.958	1.00
400_A	454_V	2.955	1.00
408_T	446_V	2.906	1.00
71_K	238_V	2.848	1.00
396_A	458_T	2.839	1.00
386_A	451_L	2.782	1.00
397_G	455_S	2.752	1.00
130_D	133_V	2.728	1.00
339_R	343_Y	2.648	1.00
139_G	353_I	2.508	1.00
266_A	279_A	2.439	1.00
151_Y	234_G	2.343	1.00
236_D	240_N	2.298	1.00
5_G	12_R	2.295	1.00
195_S	198_S	2.290	1.00
14_V	155_A	2.268	1.00
194_A	197_T	2.261	1.00
86_A	97_K	2.251	1.00
343_Y	347_A	2.232	1.00
194_A	198_S	2.223	1.00
400_A	450_V	2.163	1.00
394_T	397_G	2.144	1.00
84_F	387_V	2.142	1.00
390_W	393_V	2.120	1.00
193_G	197_T	2.110	1.00
185_A	189_A	2.105	1.00
396_A	400_A	2.104	1.00
6_D	11_G	2.103	1.00
38_G	277_D	2.067	1.00
332_A	336_Q	2.059	1.00
136_V	140_V	2.054	1.00
383_L	398_A	2.043	1.00
89_L	393_V	1.973	1.00
9_I	12_R	1.960	1.00
394_T	455_S	1.957	1.00
30_G	118_A	1.939	1.00
168_A	299_A	1.926	1.00
397_G	454_V	1.919	1.00
170_A	174_I	1.916	1.00
329_N	332_A	1.901	1.00
350_F	354_G	1.897	1.00
407_A	411_L	1.864	1.00
78_A	87_T	1.835	1.00
198_S	201_G	1.818	1.00
240_N	243_T	1.816	1.00
184_F	188_A	1.813	1.00
321_E	325_H	1.801	1.00
270_F	286_E	1.800	1.00
386_A	448_A	1.798	1.00
282_L	286_E	1.796	1.00
239_R	243_T	1.793	1.00
294_G	298_A	1.778	1.00
149_G	153_A	1.777	1.00
390_W	456_L	1.766	1.00
392_R	456_L	1.762	1.00
239_R	242_R	1.762	1.00
449_V	453_V	1.754	1.00
18_V	159_Y	1.750	1.00
325_H	337_L	1.743	1.00
339_R	342_R	1.742	1.00
324_Y	340_Y	1.741	1.00
142_V	308_A	1.731	1.00
397_G	401_S	1.667	1.00
319_V	344_V	1.666	1.00
390_W	452_V	1.655	1.00
208_A	211_G	1.653	1.00
153_A	158_D	1.653	1.00
16_P	240_N	1.650	1.00
188_A	192_N	1.588	1.00
180_W	186_D	1.579	1.00
188_A	191_D	1.560	1.00
140_V	144_G	1.552	1.00
392_R	459_T	1.549	1.00
404_T	408_T	1.543	1.00
324_Y	329_N	1.533	1.00
121_T	275_N	1.525	1.00
319_V	323_V	1.513	1.00
83_T	322_D	1.512	1.00
336_Q	339_R	1.506	1.00
132_W	357_Y	1.504	1.00
400_A	404_T	1.472	1.00
445_V	449_V	1.460	1.00
19_T	235_I	1.454	1.00
120_G	135_I	1.441	1.00
193_G	198_S	1.437	1.00
312_L	349_G	1.436	1.00
158_D	231_R	1.434	1.00
21_F	159_Y	1.434	1.00
90_N	395_A	1.408	1.00
83_T	321_E	1.384	1.00
195_S	199_I	1.383	1.00
135_I	353_I	1.380	1.00
196_L	201_G	1.378	1.00
315_A	348_I	1.374	1.00
324_Y	336_Q	1.367	1.00
133_V	136_V	1.366	1.00
88_R	387_V	1.366	1.00
133_V	137_A	1.354	1.00
394_T	459_T	1.353	1.00
328_L	332_A	1.343	1.00
196_L	199_I	1.339	1.00
103_V	406_T	1.336	1.00
139_G	349_G	1.332	1.00
65_L	385_I	1.323	1.00
155_A	158_D	1.307	1.00
207_A	211_G	1.301	1.00
338_V	342_R	1.289	1.00
142_V	305_M	1.286	1.00
8_V	341_S	1.285	1.00
319_V	324_Y	1.267	1.00
189_A	192_N	1.249	1.00
10_G	14_V	1.243	1.00
197_T	200_T	1.243	1.00
84_F	88_R	1.240	1.00
40_A	47_A	1.234	1.00
189_A	268_T	1.231	1.00
392_R	460_P	1.220	1.00
86_A	91_D	1.217	1.00
119_A	138_G	1.213	1.00
332_A	337_L	1.212	1.00
67_K	71_K	1.209	1.00
157_S	309_D	1.194	1.00
86_A	326_G	1.187	1.00
153_A	157_S	1.178	1.00
411_L	415_W	1.174	1.00
446_V	450_V	1.174	1.00
432_S	435_L	1.173	1.00
20_G	247_V	1.170	1.00
124_R	131_M	1.169	1.00
10_G	151_Y	1.164	1.00
96_V	399_V	1.162	1.00
393_V	397_G	1.162	1.00
26_S	310_S	1.156	1.00
102_F	106_V	1.150	1.00
205_G	208_A	1.150	1.00
163_A	167_A	1.148	1.00
394_T	454_V	1.141	1.00
442_P	445_V	1.135	1.00
116_I	139_G	1.134	1.00
129_V	134_G	1.130	1.00
161_Q	309_D	1.128	1.00
336_Q	340_Y	1.127	1.00
136_V	353_I	1.125	1.00
158_D	309_D	1.121	1.00
80_T	317_S	1.118	1.00
97_K	322_D	1.118	1.00
22_S	310_S	1.113	1.00
340_Y	344_V	1.112	1.00
320_V	340_Y	1.112	1.00
184_F	187_L	1.111	1.00
183_P	187_L	1.107	1.00
320_V	341_S	1.102	1.00
396_A	454_V	1.101	1.00
344_V	347_A	1.099	1.00
354_G	358_V	1.093	1.00
179_T	269_Q	1.091	1.00
363_P	366_E	1.091	1.00
68_R	71_K	1.090	1.00
145_Y	305_M	1.089	1.00
196_L	200_T	1.089	1.00
334_E	337_L	1.086	1.00
67_K	242_R	1.082	1.00
445_V	448_A	1.075	1.00
395_A	399_V	1.075	1.00
383_L	402_M	1.072	1.00
100_S	402_M	1.069	1.00
99_V	399_V	1.068	1.00
450_V	453_V	1.065	1.00
379_A	447_S	1.064	1.00
448_A	452_V	1.063	1.00
401_S	405_G	1.063	1.00
136_V	357_Y	1.063	1.00
66_A	70_R	1.061	1.00
332_A	340_Y	1.058	1.00
207_A	210_F	1.053	1.00
396_A	457_L	1.052	1.00
112_V	352_S	1.030	1.00
96_V	398_A	1.028	1.00
194_A	200_T	1.028	1.00
48_F	52_V	1.025	1.00
99_V	402_M	1.023	1.00
386_A	393_V	1.021	1.00
16_P	20_G	1.019	1.00
116_I	135_I	1.016	1.00
193_G	200_T	1.016	1.00
440_L	444_F	1.015	1.00
167_A	171_I	1.011	1.00
181_G	185_A	1.010	1.00
324_Y	328_L	1.010	1.00
85_F	100_S	1.010	1.00
145_Y	309_D	1.008	1.00
408_T	450_V	1.005	1.00
284_T	296_V	1.005	1.00
132_W	136_V	1.003	1.00
142_V	309_D	1.003	1.00
387_V	398_A	1.000	1.00
55_I	253_F	0.997	1.00
171_I	292_V	0.996	1.00
60_A	64_G	0.993	1.00
8_V	317_S	0.990	1.00
401_S	447_S	0.989	1.00
102_F	323_V	0.988	1.00
24_R	251_F	0.988	1.00
158_D	310_S	0.984	1.00
5_G	77_R	0.983	1.00
393_V	455_S	0.982	1.00
3_S	6_D	0.981	1.00
105_I	319_V	0.978	1.00
147_M	346_L	0.978	1.00
193_G	199_I	0.975	1.00
129_V	137_A	0.974	1.00
171_I	175_I	0.969	1.00
98_A	327_F	0.967	1.00
16_P	243_T	0.966	1.00
195_S	200_T	0.965	1.00
275_N	278_N	0.964	1.00
316_T	320_V	0.961	1.00
405_G	409_M	0.959	1.00
173_P	258_G	0.957	1.00
282_L	285_L	0.955	1.00
365_Y	370_N	0.952	1.00
187_L	190_M	0.944	1.00
386_A	452_V	0.943	1.00
186_D	265_Y	0.942	1.00
195_S	202_G	0.942	1.00
113_G	355_F	0.939	1.00
42_T	276_T	0.937	1.00
39_D	43_T	0.925	1.00
66_A	69_L	0.922	1.00
22_S	25_A	0.922	1.00
246_V	250_L	0.919	1.00
306_S	309_D	0.914	1.00
221_G	226_P	0.914	1.00
180_W	268_T	0.913	1.00
193_G	196_L	0.913	1.00
154_V	157_S	0.912	1.00
89_L	387_V	0.907	1.00
187_L	191_D	0.906	1.00
85_F	96_V	0.904	1.00
265_Y	269_Q	0.892	1.00
26_S	158_D	0.889	1.00
175_I	179_T	0.889	1.00
319_V	348_I	0.888	1.00
347_A	351_A	0.885	1.00
205_G	209_L	0.884	1.00
403_V	407_A	0.882	1.00
284_T	293_A	0.882	1.00
235_I	241_V	0.881	1.00
172_L	280_M	0.881	1.00
30_G	304_M	0.881	1.00
364_I	368_V	0.877	1.00
383_L	447_S	0.876	1.00
262_V	283_V	0.874	1.00
350_F	353_I	0.872	1.00
103_V	402_M	0.871	1.00
201_G	204_T	0.871	1.00
434_M	442_P	0.869	1.00
364_I	367_L	0.868	1.00
178_A	183_P	0.867	1.00
145_Y	161_Q	0.865	1.00
453_V	457_L	0.863	1.00
161_Q	302_A	0.861	1.00
22_S	155_A	0.860	1.00
22_S	26_S	0.858	1.00
448_A	451_L	0.858	1.00
392_R	461_P	0.856	1.00
29_S	111_Y	0.852	1.00
40_A	264_L	0.849	1.00
324_Y	327_F	0.847	1.00
22_S	231_R	0.846	1.00
88_R	390_W	0.845	1.00
91_D	395_A	0.845	1.00
135_I	356_A	0.845	1.00
206_W	211_G	0.844	1.00
145_Y	306_S	0.844	1.00
186_D	190_M	0.842	1.00
179_T	287_L	0.841	1.00
64_G	67_K	0.839	1.00
157_S	161_Q	0.838	1.00
281_P	284_T	0.838	1.00
459_T	462_D	0.835	1.00
53_G	57_A	0.831	1.00
325_H	330_E	0.830	1.00
25_A	231_R	0.829	1.00
396_A	459_T	0.829	1.00
313_L	316_T	0.827	1.00
390_W	397_G	0.827	1.00
194_A	199_I	0.827	1.00
202_G	205_G	0.826	1.00
341_S	345_T	0.825	1.00
21_F	162_G	0.821	1.00
176_A	179_T	0.821	1.00
197_T	201_G	0.819	1.00
449_V	452_V	0.816	1.00
50_N	62_W	0.816	1.00
203_A	206_W	0.816	1.00
446_V	449_V	0.814	1.00
191_D	194_A	0.813	1.00
370_N	374_G	0.811	1.00
156_W	159_Y	0.810	1.00
291_A	295_V	0.808	1.00
394_T	460_P	0.808	1.00
288_L	292_V	0.807	1.00
405_G	447_S	0.804	1.00
404_T	454_V	0.804	1.00
206_W	210_F	0.804	1.00
266_A	283_V	0.803	1.00
10_G	234_G	0.802	1.00
367_L	372_A	0.802	1.00
371_Y	413_T	0.802	1.00
278_N	282_L	0.800	1.00
70_R	238_V	0.799	1.00
328_L	331_Q	0.796	1.00
411_L	414_Q	0.796	1.00
390_W	455_S	0.794	1.00
405_G	408_T	0.793	1.00
45_I	264_L	0.789	1.00
169_F	259_A	0.787	1.00
124_R	128_G	0.785	1.00
16_P	247_V	0.784	1.00
55_I	249_Q	0.784	1.00
18_V	155_A	0.782	1.00
218_V	222_I	0.781	1.00
172_L	176_A	0.781	1.00
316_T	345_T	0.779	1.00
111_Y	226_P	0.776	1.00
67_K	70_R	0.776	1.00
203_A	207_A	0.776	1.00
399_V	403_V	0.774	1.00
58_D	62_W	0.772	1.00
123_L	134_G	0.772	1.00
382_P	448_A	0.770	1.00
120_G	131_M	0.769	1.00
198_S	202_G	0.769	1.00
105_I	315_A	0.769	1.00
354_G	357_Y	0.769	1.00
7_Y	345_T	0.768	1.00
452_V	455_S	0.767	1.00
161_Q	306_S	0.762	1.00
161_Q	307_S	0.761	1.00
365_Y	368_V	0.759	1.00
50_N	54_M	0.759	1.00
343_Y	346_L	0.758	1.00
198_S	205_G	0.757	1.00
161_Q	305_M	0.756	1.00
15_G	240_N	0.755	1.00
89_L	451_L	0.755	1.00
406_T	410_I	0.754	1.00
170_A	173_P	0.747	1.00
204_T	207_A	0.746	1.00
408_T	412_W	0.746	1.00
131_M	135_I	0.746	1.00
206_W	209_L	0.744	0.99
121_T	124_R	0.742	0.99
151_Y	155_A	0.741	0.99
145_Y	153_A	0.741	0.99
186_D	189_A	0.737	0.99
453_V	456_L	0.736	0.99
397_G	400_A	0.734	0.99
180_W	185_A	0.728	0.99
67_K	238_V	0.728	0.99
90_N	462_D	0.727	0.99
83_T	87_T	0.725	0.99
398_A	405_G	0.724	0.99
250_L	254_V	0.724	0.99
63_A	246_V	0.723	0.99
412_W	442_P	0.722	0.99
51_G	58_D	0.721	0.99
134_G	138_G	0.720	0.99
82_P	100_S	0.719	0.99
33_T	169_F	0.718	0.99
50_N	53_G	0.717	0.99
5_G	334_E	0.717	0.99
432_S	436_T	0.716	0.99
166_L	170_A	0.715	0.99
408_T	411_L	0.713	0.99
119_A	304_M	0.713	0.99
17_V	21_F	0.711	0.99
146_T	309_D	0.708	0.99
362_T	367_L	0.708	0.99
32_L	256_Y	0.705	0.99
59_L	63_A	0.705	0.99
115_Q	308_A	0.704	0.99
438_Y	442_P	0.704	0.99
386_A	390_W	0.704	0.99
47_A	50_N	0.703	0.99
41_Y	272_G	0.702	0.99
434_M	437_V	0.700	0.99
186_D	268_T	0.695	0.99
14_V	19_T	0.694	0.99
319_V	340_Y	0.693	0.99
27_E	54_M	0.693	0.99
345_T	349_G	0.693	0.99
143_V	346_L	0.693	0.99
235_I	240_N	0.691	0.99
121_T	277_D	0.691	0.99
402_M	405_G	0.689	0.99
305_M	309_D	0.688	0.99
390_W	394_T	0.688	0.99
457_L	460_P	0.687	0.99
222_I	226_P	0.687	0.99
205_G	211_G	0.687	0.99
117_V	121_T	0.685	0.99
167_A	170_A	0.684	0.99
324_Y	330_E	0.684	0.99
171_I	174_I	0.681	0.99
454_V	457_L	0.680	0.99
392_R	395_A	0.680	0.99
185_A	268_T	0.680	0.99
218_V	225_N	0.679	0.99
92_D	399_V	0.679	0.99
97_K	101_S	0.678	0.99
460_P	463_Q	0.678	0.99
439_G	443_A	0.677	0.99
85_F	383_L	0.674	0.99
200_T	203_A	0.674	0.99
98_A	101_S	0.673	0.99
316_T	344_V	0.672	0.99
430_A	434_M	0.671	0.99
33_T	296_V	0.669	0.99
99_V	403_V	0.667	0.99
444_F	447_S	0.662	0.99
50_N	57_A	0.661	0.99
80_T	322_D	0.661	0.99
392_R	396_A	0.659	0.99
107_F	376_L	0.657	0.99
458_T	461_P	0.655	0.99
124_R	130_D	0.655	0.99
433_G	436_T	0.655	0.99
7_Y	342_R	0.654	0.99
249_Q	253_F	0.654	0.99
175_I	178_A	0.653	0.99
152_F	156_W	0.653	0.99
447_S	451_L	0.651	0.99
283_V	287_L	0.651	0.99
267_L	279_A	0.651	0.99
177_Y	183_P	0.650	0.99
79_V	83_T	0.649	0.99
154_V	310_S	0.648	0.99
41_Y	279_A	0.645	0.99
381_G	385_I	0.645	0.99
368_V	373_W	0.644	0.99
182_L	185_A	0.643	0.99
22_S	158_D	0.642	0.99
270_F	282_L	0.642	0.99
204_T	208_A	0.641	0.98
353_I	357_Y	0.640	0.98
115_Q	307_S	0.639	0.98
14_V	234_G	0.639	0.98
431_V	435_L	0.638	0.98
400_A	403_V	0.638	0.98
100_S	104_L	0.636	0.98
96_V	100_S	0.636	0.98
64_G	68_R	0.635	0.98
25_A	161_Q	0.635	0.98
15_G	18_V	0.632	0.98
18_V	156_W	0.631	0.98
57_A	62_W	0.631	0.98
311_Q	314_V	0.631	0.98
393_V	401_S	0.629	0.98
53_G	62_W	0.628	0.98
393_V	398_A	0.628	0.98
17_V	159_Y	0.627	0.98
269_Q	283_V	0.626	0.98
39_D	42_T	0.625	0.98
154_V	231_R	0.625	0.98
90_N	96_V	0.625	0.98
25_A	162_G	0.624	0.98
6_D	152_F	0.623	0.98
312_L	345_T	0.622	0.98
29_S	33_T	0.621	0.98
182_L	189_A	0.620	0.98
331_Q	336_Q	0.617	0.98
220_L	381_G	0.617	0.98
267_L	271_G	0.616	0.98
227_H	230_V	0.616	0.98
330_E	333_T	0.616	0.98
316_T	341_S	0.616	0.98
66_A	241_V	0.615	0.98
82_P	104_L	0.614	0.98
177_Y	261_L	0.613	0.98
180_W	269_Q	0.612	0.98
262_V	280_M	0.611	0.98
26_S	231_R	0.610	0.98
4_V	8_V	0.609	0.98
177_Y	181_G	0.607	0.98
243_T	247_V	0.607	0.98
57_A	219_G	0.604	0.98
278_N	281_P	0.603	0.98
441_F	445_V	0.603	0.98
203_A	208_A	0.603	0.98
158_D	306_S	0.602	0.98
177_Y	182_L	0.601	0.98
433_G	437_V	0.601	0.98
408_T	443_A	0.600	0.98
320_V	337_L	0.600	0.98
103_V	379_A	0.599	0.98
430_A	433_G	0.597	0.98
288_L	296_V	0.596	0.98
136_V	350_F	0.595	0.98
195_S	201_G	0.594	0.98
307_S	311_Q	0.593	0.98
72_Y	77_R	0.590	0.97
15_G	19_T	0.590	0.97
397_G	450_V	0.589	0.97
62_W	67_K	0.589	0.97
370_N	373_W	0.589	0.97
260_A	264_L	0.588	0.97
443_A	447_S	0.587	0.97
437_V	440_L	0.584	0.97
89_L	386_A	0.584	0.97
172_L	296_V	0.584	0.97
154_V	158_D	0.582	0.97
252_M	256_Y	0.582	0.97
202_G	208_A	0.581	0.97
180_W	189_A	0.581	0.97
111_Y	311_Q	0.580	0.97
456_L	459_T	0.579	0.97
410_I	414_Q	0.579	0.97
407_A	410_I	0.579	0.97
382_P	451_L	0.577	0.97
435_L	438_Y	0.576	0.97
437_V	441_F	0.573	0.97
68_R	389_W	0.573	0.97
353_I	356_A	0.573	0.97
320_V	344_V	0.571	0.97
112_V	308_A	0.570	0.97
49_Y	53_G	0.570	0.97
196_L	202_G	0.570	0.97
38_G	276_T	0.567	0.97
15_G	156_W	0.566	0.97
397_G	447_S	0.564	0.97
394_T	398_A	0.564	0.97
27_E	252_M	0.563	0.97
435_L	442_P	0.563	0.97
325_H	334_E	0.563	0.97
145_Y	149_G	0.562	0.97
20_G	24_R	0.562	0.97
26_S	227_H	0.562	0.97
401_S	404_T	0.561	0.97
320_V	324_Y	0.560	0.96
139_G	356_A	0.560	0.96
143_V	147_M	0.559	0.96
121_T	125_V	0.558	0.96
164_I	298_A	0.557	0.96
392_R	455_S	0.557	0.96
398_A	401_S	0.555	0.96
24_R	162_G	0.552	0.96
161_Q	303_A	0.552	0.96
89_L	398_A	0.552	0.96
68_R	72_Y	0.550	0.96
78_A	84_F	0.550	0.96
35_G	111_Y	0.550	0.96
438_Y	441_F	0.549	0.96
24_R	255_A	0.549	0.96
232_F	245_A	0.548	0.96
25_A	157_S	0.548	0.96
219_G	226_P	0.547	0.96
26_S	146_T	0.547	0.96
285_L	293_A	0.547	0.96
177_Y	186_D	0.547	0.96
55_I	58_D	0.546	0.96
362_T	366_E	0.546	0.96
281_P	300_A	0.545	0.96
125_V	278_N	0.544	0.96
436_T	440_L	0.544	0.96
325_H	331_Q	0.544	0.96
19_T	22_S	0.543	0.96
49_Y	57_A	0.543	0.96
98_A	102_F	0.543	0.96
337_L	341_S	0.542	0.96
81_L	384_L	0.542	0.96
136_V	139_G	0.540	0.96
355_F	358_V	0.540	0.96
62_W	241_V	0.540	0.96
333_T	339_R	0.539	0.96
104_L	380_L	0.539	0.96
55_I	59_L	0.539	0.96
204_T	211_G	0.537	0.96
412_W	416_P	0.537	0.96
173_P	265_Y	0.537	0.96
117_V	131_M	0.536	0.96
120_G	134_G	0.536	0.96
173_P	261_L	0.536	0.96
394_T	452_V	0.535	0.95
181_G	184_F	0.535	0.95
289_P	292_V	0.535	0.95
109_G	351_A	0.534	0.95
254_V	258_G	0.533	0.95
218_V	226_P	0.533	0.95
243_T	246_V	0.532	0.95
27_E	373_W	0.530	0.95
269_Q	287_L	0.530	0.95
298_A	302_A	0.529	0.95
104_L	318_A	0.528	0.95
125_V	281_P	0.527	0.95
78_A	83_T	0.527	0.95
29_S	115_Q	0.527	0.95
4_V	337_L	0.527	0.95
444_F	448_A	0.527	0.95
217_A	226_P	0.526	0.95
218_V	224_G	0.526	0.95
66_A	238_V	0.525	0.95
31_W	373_W	0.524	0.95
199_I	203_A	0.523	0.95
290_S	293_A	0.522	0.95
190_M	267_L	0.522	0.95
115_Q	118_A	0.521	0.95
68_R	388_L	0.521	0.95
147_M	339_R	0.521	0.95
116_I	153_A	0.520	0.95
169_F	258_G	0.520	0.95
303_A	306_S	0.518	0.95
129_V	133_V	0.517	0.95
19_T	244_A	0.516	0.95
284_T	288_L	0.515	0.94
185_A	190_M	0.515	0.94
231_R	310_S	0.514	0.94
190_M	264_L	0.514	0.94
62_W	66_A	0.513	0.94
91_D	97_K	0.512	0.94
53_G	56_P	0.512	0.94
271_G	274_E	0.511	0.94
96_V	395_A	0.511	0.94
396_A	399_V	0.510	0.94
199_I	202_G	0.510	0.94
363_P	367_L	0.509	0.94
430_A	435_L	0.507	0.94
110_S	372_A	0.507	0.94
290_S	294_G	0.506	0.94
87_T	391_R	0.506	0.94
3_S	11_G	0.506	0.94
253_F	256_Y	0.505	0.94
36_V	40_A	0.505	0.94
447_S	450_V	0.505	0.94
91_D	326_G	0.505	0.94
311_Q	380_L	0.504	0.94
98_A	323_V	0.504	0.94
430_A	445_V	0.503	0.94
364_I	370_N	0.503	0.94
169_F	255_A	0.502	0.94
157_S	231_R	0.502	0.94
404_T	407_A	0.502	0.94
51_G	54_M	0.501	0.94
24_R	248_A	0.501	0.94
79_V	321_E	0.500	0.94

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
3dh4A	3	0.8563	100	0.315	Contact Map
2xq2A	2	0.8755	100	0.317	Contact Map
3l1lA	2	0.7797	99.4	0.857	Contact Map
3giaA	1	0.8084	99.4	0.862	Contact Map
4djkA	2	0.7969	99.1	0.879	Contact Map
2jlnA	1	0.7835	99.1	0.88	Contact Map
4wgvA	2	0.7088	98.9	0.889	Contact Map
4c7rA	3	0.7778	97.7	0.921	Contact Map
3wdoA	1	0.8295	94.3	0.943	Contact Map
2wswA	3	0.7088	93.9	0.944	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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