Q9HR13 - HALSA - GREMLIN Contacts

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Q9HR13 - Uncharacterized protein

UniProt:	Q9HR13	Sequences: MPSSPDWEGVGRVLRTPAVRIGAQFVVWCVALAALAGTVGASNGLTLSKSPKDTLAVPRWLYLATGGATIGASALLASFVTDRAFIARLDDWSYPLPSAGRLRRLAVWGGRTLGVVVLVLAVYLGFTGPALPTASFTILIAFAGGRAALPILSYVVGNVWPILNPWRAIATVLPSGFVTYPASLKRWPAVCGLLALVWVEVVFPISTVPSVLATVLVVYSVVTVAGAVLVGPEAWFHNADPVSVMLRCYGAVGIVQRYPDRVRAVLPGSRLQDPDVVTDRSDIAFVIGLVWELTYSGFITTTAGDTTIRTLTAVLPAGSTTNRAIVVYTAVFLAGYAVFLGAYLYAGRWSRRLSGTYLTSRALAVRFAPPLLAVAAGYHLAHYATLAVSLAPAMVAVSASPLVPPPNPVVLSPPGWFNAASIAFVLAGHLLAVWAAHTAAYDVFPRRLVAIKSQYPFVLVMIGYTVVSLWLLSLQGAVPPFVG	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	483 (406)
Sequences:	507 (400)
Seq/√Len:	19.8

HALSA - Q9HR13

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
178_V	229_L	5.873	1.00
400_S	405_P	5.244	1.00
401_P	405_P	5.133	1.00
226_G	239_A	4.342	1.00
341_G	345_Y	3.678	1.00
156_V	159_V	3.674	1.00
155_V	221_V	3.374	1.00
145_G	160_W	3.156	0.99
400_S	406_P	3.143	0.99
125_G	213_A	3.105	0.99
377_G	428_G	2.896	0.99
401_P	407_N	2.882	0.99
131_L	134_A	2.844	0.99
128_G	135_S	2.738	0.98
93_S	97_P	2.691	0.98
401_P	406_P	2.630	0.98
60_W	64_A	2.587	0.98
65_T	69_T	2.577	0.98
400_S	407_N	2.556	0.98
65_T	71_G	2.457	0.97
59_R	63_L	2.437	0.97
146_R	304_G	2.437	0.97
164_N	223_T	2.408	0.97
69_T	73_S	2.320	0.96
127_T	152_L	2.263	0.95
372_L	408_P	2.235	0.95
297_G	382_H	2.172	0.94
265_V	270_R	2.159	0.94
250_G	424_F	2.118	0.93
370_P	436_A	2.101	0.93
123_Y	127_T	2.094	0.93
377_G	381_A	2.082	0.92
198_W	329_T	2.072	0.92
161_P	164_N	2.055	0.92
164_N	236_F	2.027	0.91
197_V	292_E	2.005	0.91
444_F	453_S	1.991	0.90
262_V	333_L	1.951	0.90
336_Y	339_F	1.948	0.89
293_L	378_Y	1.944	0.89
67_G	70_I	1.941	0.89
271_L	435_A	1.931	0.89
249_Y	376_A	1.922	0.89
123_Y	402_L	1.885	0.88
213_A	432_A	1.862	0.87
197_V	428_G	1.856	0.87
129_P	235_W	1.839	0.86
158_N	161_P	1.823	0.86
178_V	230_V	1.806	0.85
115_V	172_V	1.787	0.85
235_W	259_P	1.763	0.84
399_A	405_P	1.748	0.83
59_R	66_G	1.722	0.83
342_A	464_Y	1.716	0.82
145_G	242_V	1.706	0.82
250_G	380_L	1.691	0.81
67_G	75_L	1.689	0.81
298_F	435_A	1.681	0.81
271_L	380_L	1.679	0.81
326_V	330_A	1.611	0.78
430_L	446_R	1.564	0.76
180_Y	184_L	1.562	0.76
190_V	193_L	1.557	0.76
192_G	241_P	1.555	0.75
164_N	240_D	1.545	0.75
148_A	391_A	1.541	0.75
190_V	281_S	1.535	0.74
417_F	421_S	1.535	0.74
349_W	352_R	1.529	0.74
468_S	472_L	1.523	0.74
227_A	236_F	1.511	0.73
60_W	63_L	1.506	0.73
387_A	391_A	1.506	0.73
187_W	271_L	1.500	0.73
189_A	244_V	1.484	0.72
249_Y	379_H	1.484	0.72
420_A	462_I	1.483	0.72
75_L	78_S	1.462	0.71
200_E	383_Y	1.458	0.70
183_S	337_A	1.451	0.70
152_L	159_V	1.436	0.69
161_P	240_D	1.434	0.69
112_T	225_A	1.434	0.69
342_A	459_L	1.427	0.69
117_V	459_L	1.426	0.69
225_A	427_A	1.414	0.68
81_T	438_T	1.414	0.68
189_A	196_L	1.405	0.68
228_V	440_A	1.405	0.68
183_S	191_C	1.398	0.67
122_V	213_A	1.396	0.67
153_S	158_N	1.394	0.67
251_A	286_V	1.373	0.66
122_V	151_I	1.360	0.65
338_V	341_G	1.360	0.65
57_V	60_W	1.355	0.65
348_R	463_G	1.349	0.64
170_A	253_G	1.345	0.64
117_V	361_R	1.342	0.64
210_S	327_V	1.340	0.64
379_H	394_M	1.336	0.64
378_Y	465_T	1.323	0.63
124_L	401_P	1.316	0.62
111_R	168_A	1.306	0.62
63_L	372_L	1.299	0.61
97_P	258_Y	1.297	0.61
128_G	421_S	1.292	0.61
122_V	361_R	1.279	0.60
136_F	377_G	1.279	0.60
161_P	236_F	1.275	0.60
353_L	456_P	1.274	0.60
304_G	331_V	1.271	0.60
429_H	437_H	1.263	0.59
423_A	427_A	1.263	0.59
145_G	282_D	1.261	0.59
330_A	346_A	1.256	0.59
115_V	168_A	1.252	0.58
157_G	165_P	1.252	0.58
112_T	116_V	1.251	0.58
218_V	222_V	1.250	0.58
389_S	417_F	1.241	0.58
288_G	371_L	1.233	0.57
95_P	98_S	1.227	0.57
255_V	262_V	1.224	0.57
351_R	442_D	1.220	0.56
440_A	459_L	1.216	0.56
77_A	86_I	1.213	0.56
248_C	397_V	1.210	0.56
63_L	66_G	1.209	0.56
149_L	195_A	1.195	0.55
157_G	382_H	1.191	0.55
200_E	293_L	1.187	0.54
222_V	267_P	1.187	0.54
125_G	137_T	1.184	0.54
59_R	70_I	1.179	0.54
236_F	240_D	1.174	0.53
149_L	152_L	1.172	0.53
139_L	394_M	1.171	0.53
162_I	337_A	1.166	0.53
77_A	431_L	1.162	0.53
190_V	289_L	1.161	0.53
136_F	243_S	1.161	0.53
330_A	340_L	1.160	0.53
121_A	140_I	1.159	0.52
339_F	351_R	1.159	0.52
161_P	237_H	1.156	0.52
225_A	306_T	1.152	0.52
429_H	465_T	1.151	0.52
155_V	360_S	1.151	0.52
118_L	216_L	1.149	0.52
57_V	62_Y	1.148	0.52
152_L	262_V	1.148	0.52
262_V	353_L	1.148	0.52
429_H	461_M	1.147	0.52
337_A	341_G	1.145	0.52
146_R	296_S	1.137	0.51
231_G	235_W	1.136	0.51
325_I	332_F	1.132	0.51
166_W	220_S	1.130	0.51
217_V	380_L	1.123	0.50
60_W	68_A	1.123	0.50
208_V	211_V	1.122	0.50
78_S	151_I	1.115	0.50
298_F	432_A	1.112	0.49
242_V	282_D	1.108	0.49
444_F	450_A	1.100	0.49
339_F	345_Y	1.100	0.49
209_P	470_W	1.098	0.49
295_Y	429_H	1.097	0.48
108_W	186_R	1.097	0.48
146_R	202_V	1.096	0.48
214_T	221_V	1.091	0.48
74_A	293_L	1.091	0.48
350_S	354_S	1.087	0.48
67_G	71_G	1.086	0.48
224_V	228_V	1.085	0.48
118_L	158_N	1.083	0.48
382_H	461_M	1.082	0.47
402_L	406_P	1.071	0.47
290_V	456_P	1.071	0.47
152_L	427_A	1.067	0.47
236_F	282_D	1.064	0.46
162_I	221_V	1.062	0.46
193_L	293_L	1.056	0.46
209_P	379_H	1.048	0.45
461_M	471_L	1.044	0.45
146_R	291_W	1.042	0.45
242_V	249_Y	1.036	0.45
135_S	421_S	1.030	0.44
113_L	450_A	1.028	0.44
390_L	393_A	1.026	0.44
337_A	349_W	1.025	0.44
70_I	238_N	1.025	0.44
61_L	64_A	1.025	0.44
293_L	377_G	1.024	0.44
253_G	326_V	1.020	0.44
164_N	215_V	1.020	0.44
225_A	395_V	1.020	0.44
120_L	250_G	1.018	0.43
209_P	213_A	1.008	0.43
75_L	459_L	1.000	0.42
468_S	471_L	0.999	0.42
145_G	239_A	0.998	0.42
90_D	104_R	0.997	0.42
128_G	428_G	0.993	0.42
241_P	408_P	0.989	0.42
152_L	417_F	0.988	0.41
188_P	461_M	0.987	0.41
230_V	286_V	0.987	0.41
123_Y	334_A	0.986	0.41
187_W	381_A	0.983	0.41
78_S	343_Y	0.979	0.41
64_A	70_I	0.976	0.41
256_Q	260_D	0.976	0.41
420_A	423_A	0.976	0.41
97_P	102_L	0.973	0.41
94_Y	97_P	0.973	0.41
62_Y	380_L	0.971	0.40
462_I	466_V	0.971	0.40
354_S	357_Y	0.969	0.40
368_A	387_A	0.969	0.40
298_F	335_G	0.965	0.40
204_P	304_G	0.964	0.40
201_V	383_Y	0.959	0.40
148_A	398_S	0.955	0.39
231_G	296_S	0.950	0.39
429_H	454_Q	0.949	0.39
434_W	463_G	0.949	0.39
345_Y	349_W	0.949	0.39
377_G	424_F	0.948	0.39
297_G	375_A	0.947	0.39
238_N	284_A	0.942	0.39
179_T	304_G	0.937	0.38
120_L	124_L	0.936	0.38
122_V	430_L	0.933	0.38
237_H	376_A	0.933	0.38
469_L	472_L	0.932	0.38
250_G	317_A	0.932	0.38
425_V	460_V	0.929	0.38
125_G	212_L	0.928	0.38
109_G	326_V	0.925	0.38
420_A	424_F	0.920	0.37
388_V	402_L	0.919	0.37
66_G	464_Y	0.919	0.37
151_I	377_G	0.917	0.37
368_A	375_A	0.917	0.37
248_C	421_S	0.908	0.37
197_V	377_G	0.904	0.36
345_Y	466_V	0.904	0.36
293_L	296_S	0.902	0.36
348_R	360_S	0.898	0.36
142_F	145_G	0.897	0.36
283_I	367_F	0.891	0.36
245_M	249_Y	0.888	0.35
419_A	423_A	0.886	0.35
223_T	236_F	0.883	0.35
291_W	471_L	0.877	0.35
64_A	68_A	0.874	0.35
251_A	435_A	0.874	0.35
150_P	171_T	0.873	0.35
71_G	75_L	0.873	0.35
212_L	379_H	0.872	0.34
66_G	439_A	0.870	0.34
62_Y	69_T	0.868	0.34
109_G	217_V	0.868	0.34
132_P	372_L	0.867	0.34
99_A	163_L	0.867	0.34
210_S	299_I	0.861	0.34
346_A	430_L	0.860	0.34
156_V	244_V	0.858	0.34
387_A	396_A	0.857	0.34
60_W	170_A	0.852	0.33
219_Y	231_G	0.850	0.33
346_A	460_V	0.850	0.33
66_G	73_S	0.849	0.33
126_F	217_V	0.847	0.33
325_I	330_A	0.845	0.33
255_V	372_L	0.844	0.33
266_L	269_S	0.843	0.33
117_V	202_V	0.842	0.33
399_A	406_P	0.841	0.33
432_A	461_M	0.838	0.33
138_I	331_V	0.835	0.32
209_P	215_V	0.834	0.32
99_A	255_V	0.832	0.32
114_G	168_A	0.832	0.32
91_D	97_P	0.831	0.32
380_L	424_F	0.831	0.32
146_R	331_V	0.828	0.32
81_T	84_A	0.828	0.32
103_R	106_A	0.827	0.32
155_V	227_A	0.827	0.32
338_V	361_R	0.822	0.32
130_A	415_G	0.821	0.32
290_V	433_V	0.819	0.31
172_V	398_S	0.817	0.31
375_A	444_F	0.816	0.31
111_R	171_T	0.815	0.31
97_P	101_R	0.815	0.31
235_W	290_V	0.813	0.31
116_V	432_A	0.812	0.31
267_P	284_A	0.810	0.31
326_V	335_G	0.808	0.31
262_V	427_A	0.807	0.31
281_S	465_T	0.806	0.31
145_G	241_P	0.804	0.31
63_L	70_I	0.804	0.31
351_R	362_A	0.802	0.30
333_L	423_A	0.800	0.30
297_G	374_V	0.800	0.30
180_Y	214_T	0.799	0.30
117_V	229_L	0.799	0.30
415_G	420_A	0.799	0.30
64_A	75_L	0.798	0.30
135_S	295_Y	0.794	0.30
179_T	356_T	0.792	0.30
137_T	213_A	0.792	0.30
105_L	225_A	0.792	0.30
188_P	231_G	0.791	0.30
148_A	152_L	0.791	0.30
400_S	403_V	0.788	0.30
330_A	341_G	0.786	0.30
297_G	301_T	0.785	0.30
250_G	285_F	0.785	0.30
212_L	247_R	0.785	0.30
117_V	423_A	0.784	0.30
118_L	193_L	0.784	0.30
243_S	246_L	0.781	0.29
296_S	382_H	0.778	0.29
169_I	259_P	0.776	0.29
147_A	196_L	0.774	0.29
343_Y	433_V	0.774	0.29
81_T	142_F	0.773	0.29
79_F	82_D	0.773	0.29
195_A	259_P	0.768	0.29
220_S	236_F	0.766	0.29
112_T	191_C	0.766	0.29
167_R	243_S	0.762	0.28
367_F	444_F	0.762	0.28
70_I	472_L	0.761	0.28
104_R	108_W	0.761	0.28
224_V	459_L	0.761	0.28
191_C	426_L	0.757	0.28
115_V	430_L	0.756	0.28
123_Y	261_R	0.755	0.28
160_W	206_S	0.754	0.28
286_V	386_L	0.753	0.28
135_S	428_G	0.752	0.28
59_R	72_A	0.751	0.28
218_V	365_V	0.748	0.28
139_L	209_P	0.746	0.28
86_I	268_G	0.745	0.27
363_L	462_I	0.743	0.27
132_P	212_L	0.743	0.27
158_N	233_E	0.742	0.27
63_L	71_G	0.742	0.27
220_S	235_W	0.742	0.27
58_P	61_L	0.740	0.27
332_F	336_Y	0.739	0.27
160_W	228_V	0.739	0.27
255_V	352_R	0.739	0.27
197_V	390_L	0.737	0.27
305_D	309_R	0.734	0.27
328_Y	339_F	0.732	0.27
58_P	63_L	0.730	0.27
116_V	310_T	0.730	0.27
162_I	262_V	0.729	0.27
109_G	337_A	0.729	0.27
143_A	193_L	0.729	0.27
141_A	242_V	0.726	0.27
403_V	464_Y	0.725	0.26
346_A	350_S	0.724	0.26
152_L	362_A	0.723	0.26
121_A	319_S	0.721	0.26
144_G	387_A	0.721	0.26
268_G	431_L	0.719	0.26
96_L	341_G	0.718	0.26
190_V	268_G	0.716	0.26
293_L	304_G	0.716	0.26
300_T	386_L	0.715	0.26
57_V	65_T	0.714	0.26
439_A	442_D	0.714	0.26
333_L	427_A	0.711	0.26
146_R	160_W	0.710	0.26
118_L	247_R	0.710	0.26
79_F	163_L	0.709	0.26
200_E	235_W	0.709	0.26
289_L	347_G	0.706	0.26
124_L	400_S	0.704	0.25
245_M	379_H	0.703	0.25
79_F	447_R	0.702	0.25
296_S	437_H	0.700	0.25
149_L	304_G	0.699	0.25
338_V	440_A	0.699	0.25
454_Q	465_T	0.698	0.25
112_T	341_G	0.696	0.25
146_R	185_K	0.696	0.25
235_W	283_I	0.694	0.25
288_G	316_P	0.693	0.25
126_F	169_I	0.691	0.25
132_P	141_A	0.690	0.25
79_F	451_I	0.687	0.25
201_V	472_L	0.687	0.25
274_P	462_I	0.687	0.25
64_A	78_S	0.686	0.25
65_T	70_I	0.686	0.25
236_F	270_R	0.685	0.24
206_S	293_L	0.684	0.24
196_L	383_Y	0.683	0.24
103_R	107_V	0.683	0.24
243_S	256_Q	0.683	0.24
105_L	301_T	0.682	0.24
306_T	354_S	0.682	0.24
142_F	285_F	0.681	0.24
150_P	198_W	0.680	0.24
98_S	179_T	0.680	0.24
365_V	372_L	0.680	0.24
276_V	427_A	0.679	0.24
163_L	342_A	0.675	0.24
122_V	217_V	0.674	0.24
211_V	221_V	0.673	0.24
372_L	439_A	0.673	0.24
61_L	417_F	0.672	0.24
150_P	238_N	0.671	0.24
145_G	293_L	0.671	0.24
325_I	329_T	0.670	0.24
87_A	261_R	0.670	0.24
122_V	446_R	0.669	0.24
178_V	458_V	0.668	0.24
395_V	417_F	0.667	0.24
352_R	355_G	0.667	0.24
378_Y	382_H	0.666	0.24
271_L	453_S	0.665	0.24
73_S	453_S	0.665	0.24
173_L	274_P	0.665	0.24
63_L	76_L	0.664	0.24
166_W	243_S	0.663	0.23
302_T	310_T	0.663	0.23
156_V	327_V	0.661	0.23
362_A	366_R	0.661	0.23
219_Y	235_W	0.660	0.23
147_A	392_P	0.660	0.23
217_V	460_V	0.660	0.23
182_A	402_L	0.659	0.23
104_R	217_V	0.659	0.23
69_T	76_L	0.658	0.23
247_R	463_G	0.657	0.23
243_S	467_V	0.657	0.23
184_L	253_G	0.657	0.23
158_N	297_G	0.655	0.23
337_A	352_R	0.651	0.23
228_V	334_A	0.650	0.23
235_W	267_P	0.649	0.23
206_S	389_S	0.649	0.23
113_L	443_V	0.648	0.23
160_W	233_E	0.645	0.23
219_Y	222_V	0.643	0.23
428_G	456_P	0.642	0.22
161_P	288_G	0.642	0.22
250_G	376_A	0.642	0.22
345_Y	352_R	0.639	0.22
389_S	460_V	0.639	0.22
310_T	467_V	0.638	0.22
325_I	328_Y	0.637	0.22
242_V	383_Y	0.635	0.22
180_Y	403_V	0.635	0.22
241_P	289_L	0.634	0.22
419_A	471_L	0.633	0.22
413_P	460_V	0.633	0.22
142_F	438_T	0.632	0.22
145_G	193_L	0.630	0.22
100_G	330_A	0.629	0.22
81_T	85_F	0.629	0.22
246_L	390_L	0.626	0.22
184_L	234_A	0.626	0.22
142_F	205_I	0.625	0.22
188_P	219_Y	0.624	0.22
164_N	180_Y	0.623	0.22
82_D	345_Y	0.622	0.22
112_T	182_A	0.621	0.22
60_W	75_L	0.620	0.22
437_H	454_Q	0.620	0.22
61_L	68_A	0.618	0.21
332_F	344_L	0.618	0.21
140_I	228_V	0.617	0.21
141_A	203_F	0.616	0.21
164_N	386_L	0.615	0.21
399_A	451_I	0.613	0.21
235_W	375_A	0.612	0.21
146_R	203_F	0.612	0.21
113_L	122_V	0.611	0.21
171_T	233_E	0.608	0.21
241_P	397_V	0.608	0.21
399_A	407_N	0.607	0.21
202_V	309_R	0.605	0.21
398_S	405_P	0.605	0.21
119_V	191_C	0.604	0.21
325_I	347_G	0.604	0.21
59_R	62_Y	0.602	0.21
166_W	382_H	0.601	0.21
134_A	304_G	0.596	0.20
126_F	213_A	0.594	0.20
169_I	464_Y	0.591	0.20
156_V	337_A	0.590	0.20
74_A	146_R	0.589	0.20
223_T	240_D	0.588	0.20
66_G	387_A	0.588	0.20
210_S	337_A	0.588	0.20
65_T	330_A	0.587	0.20
450_A	453_S	0.587	0.20
218_V	338_V	0.587	0.20
83_R	334_A	0.584	0.20
227_A	372_L	0.584	0.20
161_P	241_P	0.584	0.20
393_A	397_V	0.582	0.20
215_V	247_R	0.580	0.20
58_P	62_Y	0.579	0.20
80_V	84_A	0.577	0.20
200_E	375_A	0.577	0.20
347_G	457_F	0.576	0.20
116_V	463_G	0.575	0.20
304_G	392_P	0.575	0.20
196_L	245_M	0.572	0.19
132_P	205_I	0.571	0.19
153_S	243_S	0.570	0.19
316_P	320_T	0.569	0.19
461_M	465_T	0.568	0.19
228_V	254_I	0.567	0.19
387_A	463_G	0.567	0.19
119_V	173_L	0.567	0.19
383_Y	461_M	0.566	0.19
186_R	430_L	0.565	0.19
119_V	427_A	0.564	0.19
290_V	304_G	0.564	0.19
213_A	298_F	0.564	0.19
147_A	291_W	0.563	0.19
262_V	352_R	0.563	0.19
220_S	224_V	0.563	0.19
332_F	335_G	0.561	0.19
113_L	228_V	0.560	0.19
161_P	167_R	0.560	0.19
378_Y	461_M	0.560	0.19
155_V	287_I	0.559	0.19
249_Y	380_L	0.559	0.19
117_V	366_R	0.559	0.19
113_L	237_H	0.559	0.19
345_Y	356_T	0.558	0.19
73_S	264_A	0.557	0.19
248_C	286_V	0.554	0.19
136_F	173_L	0.553	0.19
198_W	271_L	0.551	0.19
181_P	184_L	0.548	0.19
213_A	288_G	0.547	0.19
91_D	184_L	0.546	0.18
173_L	254_I	0.545	0.18
203_F	390_L	0.545	0.18
142_F	161_P	0.545	0.18
429_H	432_A	0.543	0.18
142_F	379_H	0.543	0.18
325_I	339_F	0.541	0.18
70_I	75_L	0.540	0.18
287_I	425_V	0.538	0.18
378_Y	429_H	0.537	0.18
107_V	298_F	0.535	0.18
440_A	458_V	0.535	0.18
116_V	333_L	0.535	0.18
170_A	227_A	0.535	0.18
280_R	337_A	0.535	0.18
126_F	243_S	0.535	0.18
141_A	212_L	0.534	0.18
74_A	201_V	0.533	0.18
241_P	416_W	0.529	0.18
72_A	230_V	0.529	0.18
454_Q	461_M	0.529	0.18
148_A	378_Y	0.529	0.18
450_A	461_M	0.529	0.18
136_F	374_V	0.527	0.18
242_V	288_G	0.527	0.18
290_V	296_S	0.527	0.18
204_P	395_V	0.527	0.18
330_A	342_A	0.526	0.18
296_S	378_Y	0.526	0.18
191_C	218_V	0.525	0.18
189_A	281_S	0.522	0.18
191_C	425_V	0.520	0.17
154_Y	467_V	0.520	0.17
61_L	79_F	0.520	0.17
216_L	416_W	0.519	0.17
163_L	173_L	0.519	0.17
292_E	383_Y	0.518	0.17
158_N	240_D	0.518	0.17
365_V	427_A	0.518	0.17
90_D	173_L	0.516	0.17
253_G	449_V	0.515	0.17
160_W	227_A	0.514	0.17
248_C	377_G	0.514	0.17
350_S	471_L	0.512	0.17
437_H	461_M	0.511	0.17
367_F	469_L	0.509	0.17
63_L	125_G	0.508	0.17
96_L	345_Y	0.506	0.17
377_G	382_H	0.505	0.17
144_G	253_G	0.505	0.17
273_D	362_A	0.505	0.17
208_V	350_S	0.505	0.17
382_H	418_N	0.502	0.17
125_G	209_P	0.500	0.17
107_V	118_L	0.500	0.17
349_W	433_V	0.500	0.17

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
4lz6A	1	0.2588	5.8	0.982	Contact Map
2k1aA	1	0.087	5	0.982	Contact Map
4humA	1	0.2547	4.8	0.982	Contact Map
4httA	1	0.2484	4.4	0.983	Contact Map
4b4aA	1	0.2484	4.2	0.983	Contact Map
1sghB	1	0.0331	3.8	0.983	Contact Map
2d10E	1	0.0331	3.5	0.984	Contact Map
2lk9A	1	0.0497	3.3	0.984	Contact Map
2d11E	1	0.0331	3.3	0.984	Contact Map
2ls4A	1	0.0497	3.2	0.984	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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