Q9HR05 - HALSA - GREMLIN Contacts

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Q9HR05 - Iron transporter-like protein

UniProt:	Q9HR05	Sequences: MAARERLARIRSAVVSGDDDEPGLSLAVLAGAVAAFVSLPLAGLLVRASNYGLGHFLDVFADTSSLDVLVNSLSLVGLVTVGCVLVGVPLAVLTVQTDLPGRRAWTIIAALPLVVPSYIGAFTFVSAFGPRGDLAGALGVIGIERIPSIYGLHGAALVLILFTYPYVFLTTRAALLSFDGTLVEAARTLNHSRWQAFRRITVPQILPGVAAGGLLAALYALSDFGTPSIMRYEVYTQQIFVAQGSLGVPEGYPALLSIQLLAVVAVVLALESRIGDGDTAYVSRGASQPGRVSLGVWKWPALAFCTAIAVLSLGVPLGVLAWWFQRAGDAIFEFDPMIAWNSLKVAVAAAGVATVLALPVAGYAARSSSRLSMVSDRLTYVGYAIPGVVIALSLVFLSTEFVQSLVKTVPLLVFAYVVRFLPQAVGSVRSSVLQVDPKLTEAARTLGRSSTDAFRSVTLPLIAPGVAAGAALVFLTTMKELPATLMLRPIGFETLVSYIWLVRGAGSYGAAAVPALVLVGVSALSMVVILAQERYNG	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	537 (498)
Sequences:	4235 (3147)
Seq/√Len:	141.0

ECOLI - THIP YNJC
HALSA - Q9HR05 Q9HMT4
SULSO - Q97VC0

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
443_A	453_A	5.917	1.00
188_T	445_T	4.777	1.00
82_G	160_I	4.402	1.00
186_A	196_A	4.321	1.00
452_D	455_R	3.980	1.00
78_L	156_A	3.760	1.00
194_W	198_R	3.624	1.00
333_E	336_P	3.524	1.00
340_W	344_K	3.422	1.00
80_T	213_G	3.328	1.00
195_Q	199_R	3.328	1.00
431_S	465_G	3.310	1.00
48_A	56_F	3.294	1.00
78_L	152_L	3.170	1.00
293_S	297_W	3.076	1.00
342_S	478_M	3.001	1.00
294_L	298_K	2.977	1.00
334_F	337_M	2.973	1.00
189_L	446_L	2.920	1.00
452_D	456_S	2.880	1.00
294_L	297_W	2.847	1.00
352_V	417_V	2.832	1.00
70_V	74_S	2.828	1.00
87_G	167_V	2.780	1.00
192_S	195_Q	2.688	1.00
333_E	337_M	2.653	1.00
351_G	470_A	2.651	1.00
448_R	452_D	2.635	1.00
104_A	108_I	2.621	1.00
350_A	470_A	2.555	1.00
448_R	456_S	2.443	1.00
315_V	319_V	2.415	1.00
184_E	441_E	2.377	1.00
96_Q	183_V	2.332	1.00
191_H	448_R	2.287	1.00
269_A	273_R	2.284	1.00
295_G	299_W	2.282	1.00
295_G	301_A	2.278	1.00
348_A	413_V	2.272	1.00
84_V	213_G	2.258	1.00
167_V	216_A	2.258	1.00
294_L	300_P	2.244	1.00
449_S	452_D	2.214	1.00
74_S	152_L	2.146	1.00
195_Q	198_R	2.118	1.00
301_A	305_C	2.101	1.00
167_V	171_T	2.090	1.00
323_W	337_M	2.088	1.00
152_L	156_A	2.075	1.00
224_F	240_F	2.029	1.00
292_V	297_W	2.000	1.00
190_N	447_G	1.993	1.00
199_R	456_S	1.993	1.00
507_S	510_A	1.985	1.00
186_A	200_I	1.962	1.00
76_V	217_A	1.945	1.00
191_H	199_R	1.915	1.00
249_P	252_Y	1.911	1.00
52_G	55_H	1.875	1.00
66_L	70_V	1.867	1.00
40_P	44_L	1.850	1.00
87_G	171_T	1.850	1.00
293_S	296_V	1.846	1.00
146_I	149_I	1.837	1.00
88_V	171_T	1.830	1.00
369_S	372_S	1.817	1.00
174_A	208_G	1.788	1.00
443_A	448_R	1.787	1.00
304_F	307_A	1.767	1.00
344_K	348_A	1.765	1.00
67_D	70_V	1.762	1.00
167_V	212_G	1.750	1.00
357_A	424_A	1.746	1.00
295_G	298_K	1.743	1.00
183_V	201_T	1.721	1.00
266_V	270_L	1.679	1.00
56_F	59_V	1.667	1.00
347_V	351_G	1.662	1.00
88_V	205_I	1.659	1.00
41_L	45_L	1.654	1.00
320_L	516_L	1.649	1.00
300_P	304_F	1.643	1.00
191_H	195_Q	1.640	1.00
68_V	238_Q	1.640	1.00
300_P	303_A	1.632	1.00
156_A	160_I	1.615	1.00
345_V	413_V	1.607	1.00
193_R	196_A	1.604	1.00
346_A	350_A	1.604	1.00
349_A	477_T	1.603	1.00
292_V	296_V	1.595	1.00
72_S	221_L	1.591	1.00
152_L	232_Y	1.573	1.00
435_V	462_I	1.566	1.00
83_C	160_I	1.553	1.00
98_D	102_R	1.540	1.00
139_G	142_G	1.536	1.00
330_A	337_M	1.536	1.00
358_L	466_V	1.527	1.00
309_A	313_L	1.515	1.00
298_K	302_L	1.514	1.00
34_A	38_S	1.509	1.00
187_R	444_R	1.508	1.00
293_S	298_K	1.501	1.00
450_S	453_A	1.491	1.00
71_N	232_Y	1.476	1.00
39_L	397_L	1.475	1.00
75_L	152_L	1.472	1.00
185_A	442_A	1.470	1.00
361_A	432_V	1.469	1.00
344_K	347_V	1.445	1.00
56_F	258_I	1.444	1.00
451_T	455_R	1.442	1.00
124_F	158_V	1.441	1.00
187_R	196_A	1.440	1.00
183_V	196_A	1.424	1.00
82_G	156_A	1.417	1.00
297_W	300_P	1.407	1.00
82_G	86_V	1.406	1.00
297_W	301_A	1.405	1.00
78_L	160_I	1.390	1.00
518_L	522_S	1.382	1.00
48_A	258_I	1.363	1.00
346_A	478_M	1.363	1.00
480_E	484_T	1.359	1.00
56_F	60_F	1.356	1.00
416_Y	484_T	1.352	1.00
292_V	298_K	1.344	1.00
295_G	300_P	1.338	1.00
205_I	208_G	1.337	1.00
54_G	57_L	1.336	1.00
320_L	323_W	1.329	1.00
315_V	323_W	1.328	1.00
312_S	315_V	1.321	1.00
443_A	456_S	1.318	1.00
376_D	426_G	1.307	1.00
153_H	157_L	1.300	1.00
299_W	302_L	1.297	1.00
299_W	303_A	1.295	1.00
366_R	440_T	1.292	1.00
85_L	89_P	1.289	1.00
527_V	531_A	1.287	1.00
94_T	168_F	1.287	1.00
83_C	216_A	1.282	1.00
440_T	458_T	1.281	1.00
512_A	515_A	1.278	1.00
273_R	276_D	1.274	1.00
54_G	58_D	1.263	1.00
453_A	457_V	1.259	1.00
439_L	461_L	1.257	1.00
416_Y	477_T	1.256	1.00
311_L	315_V	1.253	1.00
303_A	307_A	1.248	1.00
44_L	393_S	1.247	1.00
325_Q	328_G	1.244	1.00
307_A	311_L	1.239	1.00
484_T	494_T	1.236	1.00
74_S	78_L	1.235	1.00
341_N	492_F	1.228	1.00
428_V	469_G	1.228	1.00
75_L	79_V	1.227	1.00
155_A	227_P	1.221	1.00
239_I	256_L	1.214	1.00
196_A	200_I	1.211	1.00
120_G	162_F	1.204	1.00
415_A	483_A	1.201	1.00
106_T	168_F	1.196	1.00
295_G	302_L	1.195	1.00
137_A	140_V	1.190	1.00
314_G	317_L	1.184	1.00
93_L	301_A	1.182	1.00
55_H	59_V	1.175	1.00
186_A	191_H	1.172	1.00
238_Q	241_V	1.171	1.00
171_T	209_V	1.160	0.99
301_A	304_F	1.159	0.99
284_R	287_S	1.155	0.99
427_S	469_G	1.153	0.99
262_A	266_V	1.146	0.99
101_G	104_A	1.145	0.99
258_I	262_A	1.141	0.99
88_V	209_V	1.138	0.99
84_V	167_V	1.138	0.99
141_I	144_E	1.136	0.99
79_V	159_L	1.134	0.99
320_L	324_F	1.133	0.99
198_R	202_V	1.132	0.99
459_L	466_V	1.123	0.99
40_P	45_L	1.123	0.99
57_L	61_A	1.117	0.99
387_G	419_R	1.116	0.99
273_R	277_G	1.114	0.99
293_S	299_W	1.113	0.99
438_K	441_E	1.111	0.99
159_L	223_D	1.103	0.99
424_A	473_V	1.101	0.99
125_V	150_Y	1.096	0.99
353_A	473_V	1.094	0.99
353_A	417_V	1.094	0.99
155_A	232_Y	1.093	0.99
49_S	52_G	1.080	0.99
42_A	46_V	1.080	0.99
521_V	525_S	1.079	0.99
90_L	164_Y	1.076	0.99
294_L	299_W	1.073	0.99
75_L	155_A	1.066	0.99
391_A	482_P	1.065	0.99
182_L	204_Q	1.065	0.99
524_L	528_V	1.063	0.99
515_A	518_L	1.061	0.99
119_I	515_A	1.055	0.99
74_S	156_A	1.053	0.99
296_V	300_P	1.051	0.99
339_A	495_L	1.047	0.99
302_L	306_T	1.046	0.99
293_S	301_A	1.043	0.99
74_S	77_G	1.042	0.99
78_L	82_G	1.041	0.99
73_L	77_G	1.041	0.99
43_G	47_R	1.036	0.99
488_R	497_S	1.030	0.99
316_P	319_V	1.029	0.99
428_V	462_I	1.029	0.99
317_L	321_A	1.028	0.99
171_T	205_I	1.027	0.99
65_S	69_L	1.026	0.99
170_T	212_G	1.025	0.99
298_K	301_A	1.017	0.99
512_A	518_L	1.015	0.99
290_G	293_S	1.013	0.99
498_Y	501_L	1.013	0.99
55_H	58_D	1.011	0.99
205_I	209_V	1.007	0.99
518_L	525_S	1.006	0.99
40_P	48_A	1.000	0.98
70_V	73_L	0.999	0.98
293_S	300_P	0.996	0.98
499_I	515_A	0.995	0.98
161_L	311_L	0.991	0.98
424_A	469_G	0.991	0.98
38_S	42_A	0.987	0.98
98_D	292_V	0.983	0.98
291_R	294_L	0.980	0.98
183_V	187_R	0.979	0.98
308_I	311_L	0.977	0.98
442_A	445_T	0.977	0.98
302_L	305_C	0.973	0.98
106_T	172_R	0.971	0.98
271_E	275_G	0.970	0.98
344_K	409_V	0.970	0.98
90_L	109_A	0.970	0.98
163_T	220_A	0.968	0.98
341_N	344_K	0.968	0.98
339_A	521_V	0.967	0.98
187_R	193_R	0.965	0.98
405_L	408_T	0.964	0.98
323_W	328_G	0.963	0.98
449_S	453_A	0.962	0.98
68_V	72_S	0.960	0.98
171_T	175_L	0.960	0.98
92_V	197_F	0.960	0.98
164_Y	168_F	0.958	0.98
345_V	409_V	0.953	0.98
420_F	473_V	0.950	0.98
233_E	238_Q	0.946	0.98
295_G	305_C	0.945	0.98
242_A	245_S	0.945	0.98
123_T	231_R	0.942	0.98
443_A	457_V	0.942	0.98
40_P	47_R	0.942	0.98
349_A	417_V	0.939	0.98
357_A	425_V	0.937	0.98
319_V	323_W	0.936	0.98
350_A	354_T	0.932	0.98
508_Y	522_S	0.931	0.98
76_V	221_L	0.929	0.98
493_E	501_L	0.928	0.97
453_A	456_S	0.926	0.97
234_V	237_Q	0.926	0.97
221_L	260_L	0.925	0.97
351_G	355_V	0.924	0.97
294_L	301_A	0.922	0.97
79_V	83_C	0.911	0.97
93_L	97_T	0.911	0.97
53_L	57_L	0.907	0.97
432_V	462_I	0.906	0.97
58_D	61_A	0.904	0.97
299_W	304_F	0.901	0.97
211_A	426_G	0.901	0.97
444_R	453_A	0.898	0.97
416_Y	480_E	0.892	0.97
289_P	292_V	0.890	0.97
71_N	237_Q	0.889	0.97
37_V	40_P	0.889	0.97
342_S	496_V	0.887	0.97
177_S	434_Q	0.884	0.97
368_S	372_S	0.881	0.97
224_F	228_S	0.881	0.97
89_P	93_L	0.878	0.97
325_Q	329_D	0.877	0.96
192_S	196_A	0.875	0.96
502_V	514_P	0.869	0.96
514_P	522_S	0.869	0.96
178_F	205_I	0.868	0.96
33_V	37_V	0.867	0.96
121_A	225_G	0.867	0.96
47_R	396_F	0.864	0.96
518_L	521_V	0.862	0.96
292_V	300_P	0.860	0.96
175_L	201_T	0.860	0.96
50_N	57_L	0.859	0.96
340_W	343_L	0.858	0.96
175_L	205_I	0.857	0.96
293_S	305_C	0.857	0.96
288_Q	294_L	0.856	0.96
238_Q	242_A	0.856	0.96
435_V	461_L	0.856	0.96
106_T	176_L	0.850	0.96
379_T	425_V	0.850	0.96
462_I	465_G	0.847	0.96
355_V	524_L	0.847	0.96
98_D	293_S	0.843	0.96
298_K	303_A	0.840	0.96
75_L	159_L	0.838	0.95
72_S	236_T	0.838	0.95
395_V	399_T	0.838	0.95
525_S	529_I	0.836	0.95
193_R	197_F	0.834	0.95
36_F	40_P	0.834	0.95
309_A	314_G	0.833	0.95
431_S	462_I	0.833	0.95
125_V	229_I	0.831	0.95
316_P	323_W	0.830	0.95
280_A	283_S	0.830	0.95
499_I	518_L	0.830	0.95
412_L	416_Y	0.828	0.95
86_V	160_I	0.827	0.95
323_W	516_L	0.827	0.95
346_A	477_T	0.827	0.95
514_P	518_L	0.826	0.95
312_S	316_P	0.823	0.95
361_A	428_V	0.822	0.95
318_G	322_W	0.821	0.95
158_V	226_T	0.820	0.95
161_L	310_V	0.819	0.95
266_V	269_A	0.819	0.95
57_L	60_F	0.818	0.95
172_R	176_L	0.818	0.95
118_Y	223_D	0.815	0.95
488_R	493_E	0.813	0.95
512_A	519_V	0.812	0.95
374_V	378_L	0.811	0.95
80_T	217_A	0.810	0.95
195_Q	452_D	0.808	0.94
296_V	304_F	0.806	0.94
517_V	520_G	0.806	0.94
360_V	379_T	0.805	0.94
508_Y	512_A	0.802	0.94
222_S	483_A	0.801	0.94
257_S	346_A	0.799	0.94
517_V	521_V	0.799	0.94
79_V	220_A	0.799	0.94
120_G	161_L	0.798	0.94
330_A	334_F	0.798	0.94
299_W	305_C	0.796	0.94
522_S	526_M	0.796	0.94
408_T	411_L	0.795	0.94
127_A	318_G	0.793	0.94
295_G	304_F	0.792	0.94
83_C	167_V	0.791	0.94
409_V	413_V	0.790	0.94
223_D	387_G	0.789	0.94
338_I	498_Y	0.788	0.94
348_A	352_V	0.788	0.94
428_V	466_V	0.787	0.94
239_I	260_L	0.782	0.93
53_L	60_F	0.782	0.93
342_S	346_A	0.781	0.93
123_T	318_G	0.778	0.93
51_Y	54_G	0.775	0.93
90_L	230_M	0.774	0.93
308_I	312_S	0.773	0.93
362_G	432_V	0.772	0.93
200_I	457_V	0.771	0.93
489_P	492_F	0.771	0.93
522_S	525_S	0.767	0.93
93_L	300_P	0.766	0.93
361_A	365_A	0.766	0.93
398_S	411_L	0.763	0.93
115_V	120_G	0.763	0.93
353_A	424_A	0.762	0.93
233_E	241_V	0.762	0.93
92_V	175_L	0.760	0.92
515_A	519_V	0.760	0.92
234_V	494_T	0.759	0.92
66_L	69_L	0.758	0.92
395_V	406_V	0.758	0.92
32_A	36_F	0.757	0.92
51_Y	56_F	0.757	0.92
384_A	387_G	0.756	0.92
225_G	480_E	0.756	0.92
507_S	518_L	0.756	0.92
455_R	459_L	0.753	0.92
69_L	263_V	0.753	0.92
354_T	470_A	0.752	0.92
236_T	260_L	0.752	0.92
80_T	84_V	0.751	0.92
291_R	295_G	0.751	0.92
135_A	139_G	0.751	0.92
360_V	425_V	0.750	0.92
343_L	347_V	0.746	0.92
75_L	234_V	0.745	0.92
523_A	527_V	0.745	0.92
103_R	106_T	0.745	0.92
86_V	164_Y	0.744	0.92
91_A	95_V	0.744	0.92
348_A	351_G	0.744	0.92
174_A	205_I	0.742	0.92
89_P	304_F	0.741	0.91
300_P	305_C	0.740	0.91
465_G	469_G	0.740	0.91
233_E	237_Q	0.739	0.91
219_Y	222_S	0.738	0.91
454_F	458_T	0.738	0.91
370_R	373_M	0.737	0.91
212_G	216_A	0.735	0.91
54_G	81_V	0.735	0.91
185_A	188_T	0.734	0.91
353_A	357_A	0.733	0.91
208_G	212_G	0.732	0.91
349_A	416_Y	0.728	0.91
485_L	497_S	0.727	0.91
330_A	333_E	0.727	0.91
42_A	45_L	0.726	0.91
133_D	137_A	0.726	0.91
306_T	310_V	0.726	0.91
406_V	411_L	0.726	0.91
362_G	366_R	0.724	0.91
98_D	103_R	0.720	0.90
29_L	33_V	0.720	0.90
37_V	44_L	0.718	0.90
87_G	90_L	0.715	0.90
323_W	326_R	0.715	0.90
398_S	418_V	0.714	0.90
223_D	479_K	0.714	0.90
367_S	372_S	0.712	0.90
358_L	428_V	0.712	0.90
508_Y	515_A	0.711	0.90
180_G	183_V	0.711	0.90
299_W	306_T	0.710	0.90
292_V	295_G	0.709	0.90
31_G	35_A	0.709	0.90
236_T	239_I	0.707	0.89
449_S	455_R	0.706	0.89
511_A	514_P	0.705	0.89
71_N	75_L	0.705	0.89
275_G	278_D	0.705	0.89
32_A	40_P	0.704	0.89
98_D	298_K	0.702	0.89
351_G	354_T	0.702	0.89
294_L	305_C	0.702	0.89
385_I	389_V	0.702	0.89
296_V	299_W	0.698	0.89
474_F	525_S	0.695	0.89
345_V	412_L	0.695	0.89
219_Y	476_T	0.695	0.89
76_V	80_T	0.693	0.89
412_L	483_A	0.693	0.89
82_G	85_L	0.693	0.89
299_W	307_A	0.690	0.88
390_I	499_I	0.690	0.88
508_Y	518_L	0.689	0.88
59_V	255_L	0.688	0.88
225_G	387_G	0.687	0.88
462_I	466_V	0.685	0.88
352_V	413_V	0.683	0.88
88_V	167_V	0.680	0.88
162_F	479_K	0.678	0.87
283_S	286_A	0.677	0.87
412_L	484_T	0.677	0.87
126_S	322_W	0.677	0.87
346_A	349_A	0.676	0.87
155_A	230_M	0.676	0.87
349_A	413_V	0.676	0.87
116_P	225_G	0.676	0.87
346_A	474_F	0.675	0.87
432_V	458_T	0.675	0.87
234_V	495_L	0.673	0.87
87_G	168_F	0.672	0.87
480_E	494_T	0.671	0.87
342_S	484_T	0.671	0.87
313_L	371_L	0.670	0.87
69_L	73_L	0.670	0.87
109_A	164_Y	0.667	0.87
371_L	374_V	0.667	0.87
71_N	74_S	0.667	0.87
223_D	482_P	0.666	0.86
154_G	240_F	0.666	0.86
401_F	405_L	0.662	0.86
296_V	352_V	0.661	0.86
228_S	500_W	0.661	0.86
143_I	151_G	0.661	0.86
197_F	202_V	0.658	0.86
242_A	252_Y	0.658	0.86
260_L	386_P	0.656	0.86
155_A	226_T	0.656	0.86
440_T	453_A	0.651	0.85
56_F	255_L	0.647	0.85
178_F	201_T	0.644	0.85
368_S	373_M	0.641	0.84
519_V	525_S	0.639	0.84
507_S	514_P	0.638	0.84
242_A	249_P	0.637	0.84
479_K	496_V	0.636	0.84
394_L	418_V	0.636	0.84
224_F	390_I	0.636	0.84
53_L	56_F	0.633	0.84
289_P	294_L	0.633	0.84
389_V	419_R	0.632	0.84
42_A	355_V	0.632	0.84
55_H	251_G	0.630	0.83
134_L	137_A	0.630	0.83
83_C	156_A	0.629	0.83
297_W	304_F	0.629	0.83
84_V	212_G	0.629	0.83
77_G	213_G	0.628	0.83
265_A	269_A	0.627	0.83
311_L	314_G	0.626	0.83
55_H	249_P	0.626	0.83
510_A	522_S	0.625	0.83
138_L	141_I	0.624	0.83
91_A	96_Q	0.624	0.83
373_M	433_L	0.624	0.83
171_T	212_G	0.622	0.83
124_F	481_L	0.622	0.83
175_L	386_P	0.622	0.83
120_G	185_A	0.620	0.82
515_A	522_S	0.619	0.82
321_A	325_Q	0.619	0.82
493_E	497_S	0.619	0.82
394_L	415_A	0.619	0.82
96_Q	201_T	0.619	0.82
410_P	413_V	0.617	0.82
31_G	375_S	0.616	0.82
275_G	280_A	0.616	0.82
298_K	307_A	0.616	0.82
229_I	502_V	0.616	0.82
448_R	457_V	0.615	0.82
90_L	94_T	0.615	0.82
423_Q	476_T	0.612	0.82
159_L	227_P	0.612	0.82
52_G	56_F	0.611	0.81
315_V	322_W	0.611	0.81
215_L	476_T	0.610	0.81
515_A	525_S	0.610	0.81
92_V	96_Q	0.609	0.81
219_Y	383_Y	0.609	0.81
94_T	97_T	0.609	0.81
88_V	175_L	0.609	0.81
366_R	437_P	0.609	0.81
63_T	67_D	0.607	0.81
304_F	308_I	0.605	0.81
354_T	428_V	0.604	0.81
73_L	194_W	0.603	0.81
88_V	92_V	0.603	0.81
118_Y	479_K	0.603	0.81
218_L	222_S	0.598	0.80
454_F	459_L	0.598	0.80
282_V	285_G	0.597	0.80
508_Y	513_V	0.597	0.80
88_V	197_F	0.596	0.80
481_L	494_T	0.596	0.80
135_A	138_L	0.595	0.80
212_G	480_E	0.595	0.80
330_A	335_D	0.594	0.80
35_A	38_S	0.594	0.80
419_R	480_E	0.593	0.79
243_Q	392_L	0.593	0.79
224_F	500_W	0.591	0.79
313_L	317_L	0.591	0.79
394_L	414_F	0.590	0.79
94_T	102_R	0.590	0.79
98_D	101_G	0.589	0.79
117_S	120_G	0.589	0.79
345_V	416_Y	0.588	0.79
239_I	253_P	0.587	0.79
121_A	393_S	0.587	0.79
235_Y	256_L	0.586	0.79
296_V	303_A	0.586	0.79
290_G	294_L	0.586	0.79
125_V	129_G	0.586	0.79
129_G	150_Y	0.585	0.79
514_P	525_S	0.584	0.78
342_S	477_T	0.584	0.78
495_L	506_G	0.584	0.78
105_W	306_T	0.583	0.78
79_V	152_L	0.583	0.78
219_Y	482_P	0.582	0.78
518_L	526_M	0.582	0.78
28_V	355_V	0.582	0.78
305_C	309_A	0.581	0.78
407_K	411_L	0.581	0.78
401_F	404_S	0.580	0.78
234_V	500_W	0.579	0.78
305_C	313_L	0.578	0.78
280_A	286_A	0.577	0.78
507_S	512_A	0.576	0.78
510_A	514_P	0.575	0.77
192_S	198_R	0.574	0.77
392_L	486_M	0.573	0.77
508_Y	514_P	0.572	0.77
513_V	516_L	0.572	0.77
494_T	500_W	0.572	0.77
125_V	232_Y	0.571	0.77
364_A	368_S	0.571	0.77
163_T	223_D	0.570	0.77
398_S	405_L	0.570	0.77
300_P	307_A	0.570	0.77
118_Y	482_P	0.568	0.77
50_N	55_H	0.567	0.76
283_S	287_S	0.566	0.76
295_G	306_T	0.565	0.76
356_L	417_V	0.565	0.76
485_L	500_W	0.564	0.76
330_A	336_P	0.560	0.76
45_L	258_I	0.560	0.76
35_A	520_G	0.560	0.76
134_L	138_L	0.559	0.75
34_A	44_L	0.559	0.75
100_P	299_W	0.559	0.75
52_G	57_L	0.558	0.75
102_R	290_G	0.557	0.75
274_I	373_M	0.557	0.75
138_L	143_I	0.557	0.75
136_G	139_G	0.556	0.75
90_L	168_F	0.556	0.75
85_L	455_R	0.556	0.75
317_L	320_L	0.554	0.75
75_L	232_Y	0.554	0.75
144_E	351_G	0.553	0.75
415_A	487_L	0.553	0.75
104_A	308_I	0.553	0.75
93_L	99_L	0.552	0.74
126_S	318_G	0.551	0.74
101_G	105_W	0.551	0.74
484_T	496_V	0.551	0.74
395_V	487_L	0.551	0.74
35_A	310_V	0.550	0.74
496_V	503_R	0.550	0.74
327_A	330_A	0.549	0.74
471_A	515_A	0.549	0.74
397_L	407_K	0.549	0.74
34_A	299_W	0.549	0.74
507_S	526_M	0.546	0.74
100_P	277_G	0.546	0.74
209_V	272_S	0.545	0.74
501_L	505_A	0.545	0.74
68_V	233_E	0.545	0.74
266_V	299_W	0.544	0.73
286_A	299_W	0.544	0.73
444_R	462_I	0.543	0.73
36_F	45_L	0.543	0.73
254_A	396_F	0.543	0.73
212_G	484_T	0.541	0.73
231_R	465_G	0.541	0.73
380_Y	422_P	0.540	0.73
83_C	164_Y	0.540	0.73
160_I	164_Y	0.539	0.73
28_V	47_R	0.539	0.73
383_Y	419_R	0.538	0.73
77_G	520_G	0.538	0.73
272_S	276_D	0.537	0.72
512_A	521_V	0.537	0.72
95_V	175_L	0.536	0.72
99_L	102_R	0.536	0.72
131_R	136_G	0.536	0.72
354_T	389_V	0.536	0.72
171_T	208_G	0.534	0.72
322_W	326_R	0.534	0.72
220_A	496_V	0.533	0.72
321_A	324_F	0.533	0.72
68_V	235_Y	0.533	0.72
168_F	172_R	0.531	0.72
202_V	206_L	0.531	0.72
163_T	219_Y	0.531	0.72
112_P	197_F	0.530	0.72
37_V	72_S	0.530	0.72
338_I	501_L	0.530	0.72
259_Q	322_W	0.529	0.71
314_G	318_G	0.528	0.71
56_F	61_A	0.527	0.71
223_D	226_T	0.527	0.71
75_L	236_T	0.524	0.71
346_A	518_L	0.524	0.71
45_L	48_A	0.524	0.71
361_A	425_V	0.524	0.71
294_L	302_L	0.524	0.71
259_Q	368_S	0.523	0.71
420_F	480_E	0.522	0.70
123_T	346_A	0.521	0.70
118_Y	481_L	0.521	0.70
345_V	484_T	0.521	0.70
483_A	487_L	0.521	0.70
293_S	307_A	0.521	0.70
113_L	166_Y	0.520	0.70
227_P	234_V	0.518	0.70
82_G	310_V	0.518	0.70
482_P	485_L	0.518	0.70
268_L	415_A	0.516	0.70
476_T	479_K	0.516	0.70
367_S	370_R	0.515	0.69
322_W	328_G	0.515	0.69
49_S	317_L	0.514	0.69
473_V	477_T	0.514	0.69
97_T	301_A	0.514	0.69
101_G	234_V	0.514	0.69
151_G	154_G	0.514	0.69
315_V	480_E	0.514	0.69
459_L	462_I	0.512	0.69
498_Y	505_A	0.511	0.69
282_V	286_A	0.511	0.69
360_V	421_L	0.510	0.69
175_L	203_P	0.509	0.68
119_I	123_T	0.509	0.68
288_Q	293_S	0.508	0.68
509_G	518_L	0.508	0.68
75_L	220_A	0.507	0.68
416_Y	494_T	0.506	0.68
291_R	297_W	0.505	0.68
166_Y	212_G	0.505	0.68
194_W	297_W	0.505	0.68
253_P	393_S	0.505	0.68
426_G	479_K	0.504	0.68
219_Y	384_A	0.504	0.68
269_A	520_G	0.504	0.68
165_P	387_G	0.504	0.68
290_G	295_G	0.504	0.68
308_I	313_L	0.504	0.68
89_P	303_A	0.503	0.68
31_G	34_A	0.503	0.68
383_Y	479_K	0.502	0.67
269_A	306_T	0.502	0.67
497_S	501_L	0.501	0.67
84_V	89_P	0.501	0.67
223_D	236_T	0.500	0.67
98_D	290_G	0.500	0.67
81_V	84_V	0.500	0.67

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
2onkC	2	0.4637	100	0.651	Contact Map
3d31C	2	0.4581	100	0.659	Contact Map
4tquM	1	0.5009	100	0.672	Contact Map
3rlfF	1	0.4991	100	0.702	Contact Map
3rlfG	1	0.4749	100	0.707	Contact Map
4tquN	1	0.4618	100	0.719	Contact Map
4ymuD	2	0.3948	99.9	0.771	Contact Map
3tuiA	2	0.3892	99.9	0.778	Contact Map
2m8rA	1	0.0801	13.6	0.975	Contact Map
3mktA	1	0.702	12	0.976	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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