Q9HQZ9 - HALSA - GREMLIN Contacts

Home
GREMLIN
- Submit - Monomer
- Submit - Complex
Contacts
Metagenomics
- Contacts
- Structures
Structures
- List
Old Projects
- Complexes (2014)
- PFAM (2013)

Q9HQZ9 - Alkanal monooxygenase homolog

UniProt:	Q9HQZ9	Sequences: MDLSVVDLSPVPDGGTAADAYANTVAAAQQADDLGYKRFWVAEHHGMETLAGTTPEVLLGHLAAETDRIRLGSGAVLVNHYSPLKVAEQFGALDGLAPGRVDAGLGRANGSPAVDRALETERHSSDPDGDHTDAVKAVLGHLHDDFPEDHAYSGIAVPGGDDEPPQPWLLGSSPSSAAIAGELGLRYCFAAFIRPQFATRAFDVYRESFTASTLPGGVDEPTGMVAVNAVCADTDAAAARRRASAEASYQRMKRGTVGTTPGVEEAIDELGGVPDPTPETLPEGDWPRAISGSPETLAGLFEQLADRVGVEEVMVQQIVPGHDAALRSHELLADAVGL	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	338 (295)
Sequences:	16346 (10481)
Seq/√Len:	610.2

ECOLI - YHBW RUTA SSUD
BACSU - YCEB YWCH YTMO YDDN YVBT SSUD YXEK MOXC
HALSA - Q9HQZ9
SULSO - Q97Y17

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
235_D	296_T	5.345	1.00
29_Q	65_E	3.360	1.00
235_D	293_S	2.879	1.00
70_R	102_D	2.763	1.00
132_T	182_E	2.636	1.00
30_Q	33_D	2.571	1.00
32_D	68_R	2.552	1.00
178_A	208_S	2.547	1.00
300_L	303_Q	2.534	1.00
203_D	207_E	2.503	1.00
63_A	97_A	2.479	1.00
235_D	239_A	2.474	1.00
234_T	237_A	2.423	1.00
59_L	71_L	2.372	1.00
293_S	296_T	2.334	1.00
136_K	183_L	2.286	1.00
302_E	306_D	2.258	1.00
149_D	154_G	2.247	1.00
129_G	151_A	2.244	1.00
232_A	237_A	2.242	1.00
177_A	204_V	2.172	1.00
22_A	98_P	2.167	1.00
207_E	211_A	2.104	1.00
202_F	206_R	2.094	1.00
209_F	221_P	2.087	1.00
202_F	223_G	2.068	1.00
28_A	62_L	2.058	1.00
25_V	29_Q	2.057	1.00
29_Q	33_D	2.055	1.00
204_V	208_S	2.046	1.00
143_H	164_P	1.950	1.00
39_F	69_I	1.936	1.00
199_T	203_D	1.932	1.00
94_D	99_G	1.892	1.00
290_I	297_L	1.885	1.00
26_A	29_Q	1.881	1.00
236_A	240_R	1.836	1.00
63_A	71_L	1.835	1.00
40_W	72_G	1.829	1.00
90_F	101_V	1.821	1.00
243_A	247_A	1.820	1.00
54_T	89_Q	1.807	1.00
25_V	65_E	1.803	1.00
181_G	208_S	1.783	1.00
233_D	327_R	1.702	1.00
208_S	211_A	1.694	1.00
139_L	164_P	1.648	1.00
62_L	71_L	1.627	1.00
30_Q	34_L	1.622	1.00
28_A	39_F	1.614	1.00
90_F	103_A	1.608	1.00
126_D	151_A	1.605	1.00
296_T	299_G	1.602	1.00
136_K	140_G	1.596	1.00
231_C	297_L	1.582	1.00
111_S	115_D	1.565	1.00
204_V	207_E	1.565	1.00
129_G	152_Y	1.555	1.00
295_E	299_G	1.530	1.00
16_T	19_D	1.508	1.00
178_A	211_A	1.482	1.00
322_H	326_L	1.480	1.00
200_R	203_D	1.477	1.00
139_L	183_L	1.467	1.00
241_R	324_A	1.461	1.00
298_A	302_E	1.456	1.00
112_P	115_D	1.456	1.00
178_A	182_E	1.435	1.00
225_V	310_V	1.430	1.00
25_V	61_H	1.429	1.00
171_G	187_Y	1.421	1.00
237_A	241_R	1.396	1.00
28_A	66_T	1.391	1.00
33_D	67_D	1.387	1.00
140_G	144_D	1.381	1.00
30_Q	326_L	1.377	1.00
302_E	305_A	1.376	1.00
209_F	214_L	1.374	1.00
32_D	66_T	1.373	1.00
231_C	294_P	1.361	1.00
140_G	145_D	1.357	1.00
61_H	64_A	1.346	1.00
139_L	167_P	1.337	1.00
296_T	300_L	1.336	1.00
132_T	183_L	1.308	1.00
34_L	326_L	1.308	1.00
280_T	283_E	1.305	1.00
299_G	303_Q	1.301	1.00
22_A	26_A	1.295	1.00
61_H	96_L	1.291	1.00
19_D	23_N	1.290	1.00
232_A	238_A	1.278	1.00
321_G	324_A	1.272	1.00
230_V	241_R	1.259	1.00
54_T	57_V	1.257	1.00
303_Q	306_D	1.254	1.00
26_A	30_Q	1.254	1.00
222_T	311_E	1.246	1.00
41_V	59_L	1.240	1.00
81_Y	89_Q	1.236	1.00
181_G	212_S	1.234	1.00
126_D	129_G	1.230	1.00
139_L	185_L	1.227	1.00
168_W	224_M	1.217	1.00
32_D	67_D	1.216	1.00
240_R	243_A	1.213	1.00
59_L	73_S	1.182	1.00
135_V	183_L	1.175	1.00
126_D	152_Y	1.173	1.00
93_L	101_V	1.172	1.00
28_A	69_I	1.172	1.00
182_E	212_S	1.171	1.00
237_A	240_R	1.167	1.00
178_A	204_V	1.166	1.00
174_P	204_V	1.164	1.00
72_G	102_D	1.162	1.00
86_V	134_A	1.160	1.00
138_V	142_L	1.157	1.00
266_A	269_E	1.156	1.00
53_T	92_A	1.145	1.00
132_T	136_K	1.142	1.00
233_D	237_A	1.139	1.00
168_W	186_R	1.137	1.00
118_L	121_E	1.136	1.00
57_V	60_G	1.132	1.00
178_A	212_S	1.131	1.00
197_F	200_R	1.124	1.00
175_S	178_A	1.119	1.00
137_A	153_S	1.118	1.00
105_L	135_V	1.115	1.00
282_P	285_D	1.112	1.00
29_Q	67_D	1.108	1.00
136_K	148_E	1.104	1.00
103_A	138_V	1.103	1.00
41_V	62_L	1.098	1.00
240_R	244_S	1.096	1.00
161_D	164_P	1.085	1.00
23_N	26_A	1.083	1.00
290_I	300_L	1.080	1.00
85_K	89_Q	1.078	1.00
130_D	133_D	1.072	1.00
61_H	65_E	1.070	1.00
56_E	89_Q	1.068	1.00
239_A	243_A	1.065	1.00
242_R	246_E	1.059	1.00
208_S	212_S	1.057	1.00
199_T	308_V	1.055	1.00
251_R	254_R	1.049	1.00
237_A	324_A	1.047	1.00
264_E	268_D	1.047	1.00
195_P	303_Q	1.047	1.00
292_G	297_L	1.046	1.00
260_T	263_V	1.042	1.00
194_R	197_F	1.041	1.00
222_T	312_E	1.035	1.00
229_A	315_V	1.034	1.00
75_A	170_L	1.029	1.00
57_V	93_L	1.022	1.00
137_A	140_G	1.018	1.00
18_A	22_A	1.017	1.00
94_D	163_E	1.011	1.00
26_A	326_L	1.011	1.00
23_N	322_H	1.010	1.00
139_L	143_H	1.003	1.00
209_F	218_V	1.000	1.00
76_V	86_V	0.998	1.00
26_A	322_H	0.997	1.00
200_R	204_V	0.995	1.00
133_D	150_H	0.982	1.00
129_G	175_S	0.981	1.00
179_I	183_L	0.976	1.00
94_D	162_D	0.976	1.00
137_A	155_I	0.974	1.00
265_E	268_D	0.967	1.00
132_T	179_I	0.962	1.00
264_E	267_I	0.953	1.00
242_R	291_S	0.951	1.00
227_V	290_I	0.946	1.00
280_T	284_G	0.944	1.00
180_A	187_Y	0.936	1.00
144_D	147_P	0.934	1.00
30_Q	323_D	0.930	1.00
38_R	72_G	0.927	1.00
232_A	241_R	0.920	1.00
56_E	76_V	0.918	1.00
126_D	130_D	0.912	1.00
75_A	106_G	0.904	1.00
188_C	224_M	0.903	1.00
210_T	218_V	0.903	1.00
133_D	151_A	0.898	1.00
299_G	302_E	0.898	1.00
148_E	151_A	0.892	1.00
21_Y	96_L	0.890	1.00
258_G	261_P	0.888	1.00
279_E	282_P	0.886	1.00
261_P	265_E	0.885	1.00
22_A	25_V	0.882	1.00
177_A	208_S	0.881	1.00
26_A	323_D	0.880	1.00
227_V	301_F	0.879	1.00
195_P	199_T	0.878	1.00
236_A	239_A	0.876	1.00
140_G	147_P	0.865	1.00
26_A	33_D	0.865	1.00
59_L	63_A	0.865	1.00
263_V	268_D	0.863	1.00
244_S	247_A	0.863	1.00
157_V	160_G	0.855	1.00
78_V	134_A	0.852	1.00
130_D	134_A	0.850	1.00
234_T	238_A	0.848	1.00
177_A	181_G	0.847	1.00
60_G	64_A	0.847	1.00
206_R	223_G	0.847	1.00
262_G	266_A	0.845	1.00
137_A	148_E	0.841	1.00
94_D	164_P	0.834	1.00
263_V	266_A	0.833	1.00
157_V	161_D	0.832	1.00
133_D	137_A	0.829	1.00
281_L	285_D	0.825	1.00
158_P	161_D	0.824	1.00
169_L	180_A	0.823	1.00
38_R	312_E	0.821	1.00
142_L	165_P	0.821	1.00
83_P	137_A	0.818	1.00
243_A	246_E	0.818	1.00
63_A	101_V	0.816	1.00
134_A	138_V	0.814	1.00
261_P	264_E	0.812	1.00
108_A	113_A	0.810	1.00
202_F	205_Y	0.805	1.00
209_F	212_S	0.802	1.00
256_T	260_T	0.799	1.00
20_A	23_N	0.798	1.00
262_G	265_E	0.796	1.00
265_E	269_E	0.795	1.00
64_A	97_A	0.792	1.00
121_E	125_S	0.787	1.00
95_G	163_E	0.780	1.00
178_A	207_E	0.780	1.00
244_S	248_S	0.777	1.00
203_D	309_G	0.773	1.00
140_G	148_E	0.771	1.00
206_R	210_T	0.769	1.00
281_L	284_G	0.762	1.00
94_D	161_D	0.761	1.00
169_L	176_S	0.754	1.00
209_F	219_D	0.752	1.00
133_D	152_Y	0.751	1.00
239_A	286_W	0.751	1.00
132_T	175_S	0.749	1.00
102_D	168_W	0.746	1.00
174_P	208_S	0.745	1.00
59_L	101_V	0.742	1.00
78_V	86_V	0.739	1.00
128_D	175_S	0.738	1.00
63_A	93_L	0.736	1.00
252_M	255_G	0.730	1.00
76_V	90_F	0.728	1.00
241_R	244_S	0.727	1.00
90_F	142_L	0.726	1.00
214_L	218_V	0.726	1.00
205_Y	209_F	0.726	1.00
187_Y	205_Y	0.725	1.00
324_A	327_R	0.716	1.00
86_V	138_V	0.713	1.00
40_W	74_G	0.711	1.00
239_A	291_S	0.706	1.00
141_H	147_P	0.705	1.00
77_L	108_A	0.704	1.00
23_N	27_A	0.703	1.00
25_V	62_L	0.701	1.00
133_D	136_K	0.701	1.00
21_Y	61_H	0.694	1.00
45_H	88_E	0.693	1.00
177_A	187_Y	0.693	1.00
22_A	64_A	0.693	1.00
140_G	143_H	0.691	1.00
279_E	283_E	0.690	1.00
83_P	134_A	0.685	1.00
174_P	178_A	0.685	1.00
197_F	201_A	0.684	1.00
17_A	20_A	0.684	1.00
59_L	93_L	0.683	1.00
150_H	153_S	0.683	1.00
202_F	308_V	0.682	1.00
43_E	81_Y	0.681	1.00
169_L	184_G	0.679	1.00
224_M	312_E	0.678	1.00
73_S	101_V	0.677	1.00
82_S	85_K	0.677	1.00
263_V	267_I	0.674	1.00
189_F	201_A	0.672	1.00
323_D	326_L	0.671	1.00
239_A	242_R	0.671	1.00
95_G	160_G	0.670	1.00
81_Y	85_K	0.670	1.00
209_F	220_E	0.669	1.00
169_L	179_I	0.668	1.00
136_K	182_E	0.666	1.00
160_G	163_E	0.663	1.00
37_K	68_R	0.658	1.00
39_F	62_L	0.654	1.00
98_P	160_G	0.652	1.00
41_V	58_L	0.651	1.00
260_T	265_E	0.651	1.00
259_T	264_E	0.649	1.00
182_E	211_A	0.649	1.00
70_R	166_Q	0.649	1.00
196_Q	199_T	0.649	1.00
38_R	314_M	0.648	1.00
182_E	208_S	0.647	1.00
125_S	175_S	0.644	1.00
205_Y	221_P	0.641	1.00
264_E	269_E	0.640	1.00
248_S	251_R	0.640	1.00
25_V	28_A	0.638	1.00
71_L	97_A	0.638	1.00
121_E	126_D	0.638	1.00
25_V	64_A	0.636	1.00
259_T	262_G	0.636	1.00
263_V	269_E	0.631	1.00
130_D	153_S	0.631	1.00
22_A	67_D	0.631	1.00
31_A	69_I	0.630	1.00
107_R	131_H	0.630	1.00
181_G	209_F	0.629	1.00
229_A	290_I	0.627	1.00
107_R	127_P	0.626	1.00
235_D	238_A	0.626	1.00
206_R	209_F	0.625	1.00
223_G	310_V	0.624	1.00
136_K	139_L	0.621	1.00
214_L	219_D	0.621	1.00
84_L	141_H	0.619	1.00
60_G	93_L	0.618	1.00
212_S	218_V	0.617	1.00
251_R	255_G	0.617	1.00
66_T	100_R	0.614	1.00
206_R	311_E	0.613	1.00
323_D	327_R	0.612	1.00
198_A	201_A	0.610	1.00
37_K	70_R	0.605	1.00
233_D	294_P	0.603	1.00
56_E	90_F	0.601	1.00
295_E	298_A	0.600	1.00
32_D	69_I	0.598	1.00
280_T	285_D	0.596	1.00
177_A	205_Y	0.596	1.00
305_A	310_V	0.595	1.00
247_A	251_R	0.595	1.00
21_Y	25_V	0.594	1.00
175_S	179_I	0.594	1.00
322_H	325_A	0.593	1.00
105_L	167_P	0.592	1.00
131_H	134_A	0.592	1.00
72_G	168_W	0.591	1.00
300_L	304_L	0.589	1.00
66_T	69_I	0.582	1.00
60_G	97_A	0.582	1.00
205_Y	223_G	0.580	1.00
58_L	92_A	0.579	1.00
94_D	97_A	0.578	1.00
238_A	242_R	0.577	1.00
171_G	176_S	0.576	1.00
117_A	121_E	0.575	1.00
279_E	284_G	0.575	1.00
288_R	300_L	0.575	1.00
158_P	163_E	0.575	1.00
250_Q	254_R	0.574	1.00
57_V	89_Q	0.573	1.00
119_E	122_R	0.573	1.00
172_S	201_A	0.572	1.00
105_L	138_V	0.571	1.00
81_Y	86_V	0.569	1.00
232_A	235_D	0.569	1.00
168_W	222_T	0.568	1.00
206_R	309_G	0.568	1.00
172_S	191_A	0.564	1.00
262_G	269_E	0.564	1.00
174_P	200_R	0.562	1.00
301_F	315_V	0.560	1.00
61_H	97_A	0.560	1.00
301_F	313_V	0.557	1.00
206_R	218_V	0.556	1.00
226_A	314_M	0.555	1.00
230_V	242_R	0.554	1.00
19_D	22_A	0.554	1.00
203_D	206_R	0.553	1.00
83_P	153_S	0.553	1.00
137_A	147_P	0.552	1.00
207_E	210_T	0.551	0.99
94_D	159_G	0.551	0.99
166_Q	222_T	0.551	0.99
91_G	142_L	0.549	0.99
294_P	298_A	0.548	0.99
259_T	268_D	0.547	0.99
254_R	278_P	0.546	0.99
253_K	256_T	0.545	0.99
158_P	162_D	0.544	0.99
57_V	61_H	0.541	0.99
259_T	266_A	0.541	0.99
234_T	240_R	0.540	0.99
156_A	160_G	0.540	0.99
55_P	73_S	0.538	0.99
133_D	148_E	0.538	0.99
164_P	185_L	0.537	0.99
246_E	249_Y	0.535	0.99
78_V	105_L	0.534	0.99
248_S	252_M	0.534	0.99
231_C	293_S	0.534	0.99
104_G	170_L	0.533	0.99
260_T	268_D	0.531	0.99
202_F	310_V	0.531	0.99
97_A	101_V	0.530	0.99
260_T	264_E	0.528	0.99
74_G	188_C	0.526	0.99
297_L	300_L	0.524	0.99
256_T	261_P	0.521	0.99
135_V	169_L	0.521	0.99
109_N	113_A	0.521	0.99
256_T	259_T	0.520	0.99
206_R	220_E	0.519	0.99
260_T	267_I	0.519	0.99
57_V	96_L	0.518	0.99
122_R	125_S	0.516	0.99
142_L	167_P	0.515	0.99
87_A	142_L	0.514	0.99
56_E	60_G	0.514	0.99
94_D	165_P	0.513	0.99
60_G	63_A	0.511	0.99
156_A	161_D	0.511	0.99
196_Q	200_R	0.510	0.99
91_G	160_G	0.508	0.99
206_R	219_D	0.508	0.99
278_P	282_P	0.506	0.99
168_W	312_E	0.504	0.99
91_G	95_G	0.503	0.99
304_L	308_V	0.502	0.99
156_A	159_G	0.502	0.99
128_D	179_I	0.500	0.99

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
1lucA	1	0.926	100	0.194	Contact Map
1lucB	1	0.926	100	0.197	Contact Map
4us5A	3	0.9497	100	0.202	Contact Map
2wgkA	2	0.9704	100	0.211	Contact Map
2i7gA	2	0.9467	100	0.225	Contact Map
1z69A	4	0.932	100	0.238	Contact Map
1f07A	3	0.926	100	0.241	Contact Map
1ezwA	3	0.932	100	0.246	Contact Map
3b9oA	2	0.9704	100	0.251	Contact Map
3raoA	2	0.9497	100	0.261	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.0102 seconds.