Q9HQZ0 - HALSA - GREMLIN Contacts

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Q9HQZ0 - Acetyl-CoA synthetase

UniProt:	Q9HQZ0	Sequences: MSQSGAFITAVLDWANDQGIGFKDIASLGNKAVLSETDFMQAWADDPDTNVILGYLEGVDDGREFIDDAREVTQDTPAVVVKSGRTEAGAQAASSHTGTIAGSEAAYEAGFKQAGVVRAENVQELFDFARALDGLPMPDSEDVAVITNAGGPGVMATDAVGDSRLSMASFEDDTIDALQGSMPDEANVYNPVDVIGDAEIDRFRTAIDTVLADEHVGCALVLSAPTAVIDYTELSGVITALQEKHNKPVVTCLMGGERTEQATDVLGDAGIPNYFDPARAIGSLDALAVQREVESRDYQAPTAFDVDRDAARDILEDAADRGATRLGVEAMDLLDAYGIPTPTGDVVDSPDAARRVARDIEGDVVMKIVSPDILHKSDIGGVKVGVETDAVADAYEDLITRATNYQPDATILGIQVQEMVDVDAGTETILGMNRDPQFGPLLLFGLGGIFVEILEDTSVRVAPVSEREAGDMIDDLDSAPLLRGARGRDPADEAAITEAIQRLSQLVTDFPAILELDVNPLLATGDSATALDVQLTIDPDEL	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	542 (533)
Sequences:	2455 (1834)
Seq/√Len:	79.4

ECOLI - PKA
HALSA - Q9HQZ0
SULSO - Q97XD9

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
345_D	359_D	5.035	1.00
386_V	391_V	4.543	1.00
142_D	217_G	4.484	1.00
104_E	118_R	4.345	1.00
430_L	503_L	4.332	1.00
337_Y	509_D	3.936	1.00
432_M	507_V	3.865	1.00
518_V	521_L	3.797	1.00
383_K	397_D	3.780	1.00
350_P	396_E	3.294	1.00
333_L	535_L	3.128	1.00
343_T	418_E	3.083	1.00
140_S	217_G	2.922	1.00
364_V	416_V	2.846	1.00
108_E	118_R	2.818	1.00
366_M	416_V	2.815	1.00
499_A	521_L	2.815	1.00
460_R	472_M	2.774	1.00
522_L	531_L	2.774	1.00
323_A	329_E	2.730	1.00
466_E	498_E	2.726	1.00
474_D	493_E	2.702	1.00
339_I	530_A	2.684	1.00
444_F	476_L	2.653	1.00
365_V	384_V	2.647	1.00
386_V	394_A	2.622	1.00
428_T	496_I	2.606	1.00
460_R	475_D	2.513	1.00
349_S	352_A	2.501	1.00
351_D	392_A	2.486	1.00
354_R	391_V	2.468	1.00
349_S	395_Y	2.468	1.00
443_L	459_V	2.445	1.00
395_Y	414_I	2.441	1.00
446_L	478_S	2.360	1.00
453_I	485_A	2.349	1.00
372_D	410_T	2.310	1.00
69_A	116_V	2.308	1.00
106_A	441_L	2.281	1.00
345_D	356_V	2.209	1.00
147_T	153_G	2.203	1.00
171_E	215_H	2.190	1.00
107_Y	111_F	2.188	1.00
398_L	402_A	2.158	1.00
326_L	329_E	2.149	1.00
464_V	500_I	2.141	1.00
362_G	388_T	2.132	1.00
174_T	213_D	2.125	1.00
46_D	49_T	2.100	1.00
470_G	494_A	2.094	1.00
177_A	212_A	2.092	1.00
354_R	392_A	2.086	1.00
365_V	419_M	2.057	1.00
350_P	354_R	2.044	1.00
498_E	502_R	2.025	1.00
362_G	391_V	2.024	1.00
347_V	356_V	1.993	1.00
141_E	292_E	1.965	1.00
398_L	401_R	1.953	1.00
458_S	472_M	1.920	1.00
53_L	129_A	1.920	1.00
23_K	49_T	1.911	1.00
348_D	352_A	1.882	1.00
69_A	78_A	1.879	1.00
368_I	373_I	1.858	1.00
327_G	331_M	1.850	1.00
127_D	279_R	1.846	1.00
372_D	409_A	1.830	1.00
52_I	72_V	1.829	1.00
80_V	116_V	1.828	1.00
353_A	391_V	1.817	1.00
518_V	530_A	1.810	1.00
34_L	39_F	1.809	1.00
208_D	244_K	1.802	1.00
54_G	80_V	1.792	1.00
141_E	166_S	1.787	1.00
346_V	369_V	1.780	1.00
168_A	216_V	1.770	1.00
182_M	186_A	1.758	1.00
236_G	240_A	1.756	1.00
444_F	473_I	1.755	1.00
379_I	402_A	1.751	1.00
366_M	395_Y	1.747	1.00
374_L	534_Q	1.739	1.00
383_K	394_A	1.731	1.00
395_Y	399_I	1.730	1.00
473_I	497_T	1.729	1.00
144_A	216_V	1.703	1.00
474_D	479_A	1.694	1.00
503_L	516_L	1.688	1.00
358_R	362_G	1.688	1.00
8_I	25_I	1.686	1.00
119_A	128_F	1.676	1.00
113_Q	460_R	1.667	1.00
383_K	398_L	1.661	1.00
331_M	344_G	1.660	1.00
442_L	462_A	1.651	1.00
61_D	64_E	1.647	1.00
470_G	497_T	1.629	1.00
353_A	361_E	1.606	1.00
296_R	471_D	1.603	1.00
124_E	282_G	1.601	1.00
211_L	219_A	1.596	1.00
366_M	391_V	1.586	1.00
429_I	443_L	1.564	1.00
495_A	527_S	1.562	1.00
466_E	501_Q	1.560	0.99
353_A	357_A	1.556	0.99
26_A	43_W	1.553	0.99
350_P	392_A	1.550	0.99
179_Q	188_V	1.546	0.99
387_E	390_A	1.535	0.99
360_I	418_E	1.530	0.99
466_E	497_T	1.527	0.99
204_R	240_A	1.522	0.99
239_T	265_V	1.515	0.99
121_N	278_A	1.507	0.99
82_K	104_E	1.504	0.99
506_L	510_F	1.491	0.99
41_Q	71_E	1.485	0.99
510_F	513_I	1.482	0.99
230_D	233_E	1.480	0.99
398_L	414_I	1.479	0.99
40_M	52_I	1.464	0.99
431_G	517_D	1.456	0.99
497_T	501_Q	1.454	0.99
521_L	530_A	1.438	0.99
36_E	56_L	1.435	0.99
357_A	364_V	1.429	0.99
429_I	451_V	1.429	0.99
171_E	213_D	1.428	0.99
111_F	116_V	1.424	0.99
264_D	268_D	1.419	0.99
393_D	397_D	1.416	0.99
432_M	503_L	1.411	0.99
492_D	527_S	1.409	0.99
492_D	495_A	1.405	0.99
85_R	162_D	1.403	0.99
366_M	414_I	1.402	0.99
474_D	483_R	1.399	0.99
499_A	528_A	1.383	0.99
172_D	176_D	1.381	0.99
56_L	80_V	1.380	0.99
491_A	523_A	1.379	0.99
170_F	216_V	1.376	0.99
368_I	381_G	1.371	0.99
506_L	513_I	1.367	0.99
515_E	536_T	1.360	0.99
456_D	477_D	1.354	0.99
383_K	401_R	1.352	0.99
428_T	523_A	1.349	0.99
208_D	212_A	1.346	0.98
185_E	195_I	1.342	0.98
394_A	398_L	1.335	0.98
170_F	210_V	1.334	0.98
177_A	180_G	1.329	0.98
325_R	535_L	1.328	0.98
465_S	468_E	1.323	0.98
79_V	132_L	1.323	0.98
172_D	175_I	1.319	0.98
350_P	395_Y	1.315	0.98
357_A	361_E	1.308	0.98
469_A	501_Q	1.306	0.98
38_D	64_E	1.302	0.98
344_G	417_Q	1.291	0.98
315_L	319_A	1.290	0.98
146_I	210_V	1.283	0.98
113_Q	461_V	1.273	0.98
397_D	401_R	1.272	0.98
330_A	535_L	1.271	0.98
469_A	500_I	1.268	0.98
378_D	486_R	1.263	0.98
476_L	480_P	1.256	0.98
44_A	72_V	1.252	0.98
207_I	219_A	1.250	0.98
396_E	400_T	1.248	0.98
462_A	504_S	1.246	0.98
141_E	288_A	1.246	0.98
218_C	284_L	1.245	0.97
131_A	283_S	1.244	0.97
95_S	515_E	1.242	0.97
499_A	518_V	1.231	0.97
464_V	469_A	1.229	0.97
186_A	195_I	1.228	0.97
226_T	229_I	1.226	0.97
285_D	289_V	1.224	0.97
45_D	71_E	1.222	0.97
82_K	118_R	1.222	0.97
205_T	208_D	1.217	0.97
370_S	373_I	1.215	0.97
386_V	390_A	1.212	0.97
113_Q	468_E	1.210	0.97
110_G	461_V	1.209	0.97
66_I	110_G	1.208	0.97
144_A	210_V	1.199	0.97
450_F	485_A	1.181	0.97
79_V	119_A	1.175	0.96
197_D	202_R	1.173	0.96
428_T	476_L	1.172	0.96
354_R	362_G	1.172	0.96
479_A	493_E	1.168	0.96
361_E	364_V	1.164	0.96
334_L	533_V	1.157	0.96
428_T	521_L	1.155	0.96
350_P	391_V	1.152	0.96
513_I	535_L	1.148	0.96
214_E	247_K	1.144	0.96
181_S	209_T	1.144	0.96
100_I	451_V	1.144	0.96
37_T	68_D	1.143	0.96
177_A	209_T	1.141	0.96
40_M	68_D	1.140	0.96
363_D	391_V	1.136	0.96
420_V	529_T	1.130	0.96
357_A	362_G	1.128	0.95
375_H	519_N	1.128	0.95
176_D	180_G	1.121	0.95
353_A	364_V	1.121	0.95
289_V	292_E	1.120	0.95
169_S	172_D	1.114	0.95
207_I	241_L	1.110	0.95
363_D	388_T	1.108	0.95
330_A	533_V	1.108	0.95
80_V	111_F	1.104	0.95
326_L	369_V	1.103	0.95
458_S	475_D	1.102	0.95
290_Q	294_E	1.095	0.95
483_R	493_E	1.093	0.95
479_A	483_R	1.091	0.95
473_I	496_I	1.090	0.95
171_E	174_T	1.089	0.95
236_G	265_V	1.089	0.95
470_G	474_D	1.087	0.94
170_F	174_T	1.086	0.94
399_I	414_I	1.081	0.94
368_I	402_A	1.079	0.94
163_S	285_D	1.077	0.94
78_A	116_V	1.072	0.94
368_I	411_I	1.069	0.94
89_G	92_A	1.068	0.94
430_L	500_I	1.066	0.94
312_R	512_A	1.066	0.94
342_P	420_V	1.065	0.94
426_T	488_R	1.062	0.94
384_V	419_M	1.061	0.94
233_E	236_G	1.061	0.94
503_L	518_V	1.058	0.94
426_T	491_A	1.055	0.94
307_D	310_A	1.054	0.94
44_A	68_D	1.054	0.94
469_A	504_S	1.053	0.94
211_L	247_K	1.052	0.93
239_T	269_A	1.049	0.93
93_A	154_V	1.044	0.93
440_P	462_A	1.042	0.93
123_Q	279_R	1.032	0.93
174_T	214_E	1.028	0.93
7_F	122_V	1.022	0.92
112_K	475_D	1.021	0.92
251_T	273_N	1.020	0.92
131_A	287_L	1.016	0.92
220_L	280_A	1.015	0.92
24_D	49_T	1.015	0.92
31_K	60_D	1.014	0.92
24_D	43_W	1.011	0.92
464_V	472_M	1.008	0.92
44_A	71_E	1.008	0.92
156_A	220_L	1.003	0.92
160_V	165_L	1.003	0.92
178_L	206_A	1.001	0.92
143_V	284_L	0.998	0.92
137_M	291_R	0.991	0.91
402_A	414_I	0.984	0.91
315_L	510_F	0.981	0.91
409_A	413_G	0.979	0.91
143_V	160_V	0.977	0.91
513_I	516_L	0.976	0.91
377_S	486_R	0.973	0.90
455_E	480_P	0.973	0.90
181_S	205_T	0.964	0.90
339_I	499_A	0.963	0.90
324_T	536_T	0.958	0.90
328_V	332_D	0.957	0.90
331_M	417_Q	0.955	0.90
447_G	519_N	0.953	0.90
356_V	359_D	0.953	0.90
86_T	89_G	0.952	0.90
391_V	395_Y	0.949	0.89
469_A	472_M	0.949	0.89
21_G	33_V	0.946	0.89
26_A	39_F	0.946	0.89
402_A	411_I	0.945	0.89
104_E	108_E	0.942	0.89
456_D	476_L	0.941	0.89
92_A	154_V	0.941	0.89
377_S	449_I	0.940	0.89
96_H	150_G	0.940	0.89
35_S	61_D	0.939	0.89
375_H	486_R	0.936	0.89
250_V	284_L	0.933	0.89
337_Y	510_F	0.932	0.89
12_L	25_I	0.932	0.89
59_V	107_Y	0.925	0.88
44_A	78_A	0.922	0.88
379_I	401_R	0.921	0.88
429_I	445_G	0.920	0.88
120_E	162_D	0.919	0.88
365_V	420_V	0.917	0.88
176_D	179_Q	0.917	0.88
333_L	506_L	0.916	0.88
314_I	318_A	0.916	0.88
175_I	188_V	0.913	0.87
473_I	476_L	0.912	0.87
494_A	497_T	0.912	0.87
333_L	336_A	0.906	0.87
201_D	205_T	0.906	0.87
310_A	313_D	0.903	0.87
452_E	486_R	0.901	0.87
370_S	411_I	0.900	0.87
426_T	484_G	0.895	0.86
472_M	475_D	0.890	0.86
41_Q	64_E	0.890	0.86
310_A	332_D	0.889	0.86
18_Q	130_R	0.889	0.86
121_N	124_E	0.888	0.86
113_Q	475_D	0.885	0.86
466_E	494_A	0.884	0.86
112_K	289_V	0.883	0.86
400_T	404_N	0.881	0.86
327_G	330_A	0.880	0.85
442_L	464_V	0.877	0.85
179_Q	186_A	0.874	0.85
366_M	398_L	0.870	0.85
366_M	386_V	0.870	0.85
49_T	76_T	0.867	0.85
376_K	532_D	0.867	0.85
152_P	254_M	0.866	0.85
84_G	158_D	0.866	0.85
484_G	487_G	0.862	0.84
498_E	501_Q	0.862	0.84
171_E	214_E	0.858	0.84
351_D	354_R	0.853	0.84
460_R	468_E	0.852	0.84
31_K	36_E	0.852	0.84
388_T	391_V	0.850	0.83
472_M	476_L	0.848	0.83
24_D	42_A	0.847	0.83
317_D	321_R	0.846	0.83
1_M	43_W	0.846	0.83
326_L	412_L	0.842	0.83
345_D	360_I	0.842	0.83
354_R	358_R	0.841	0.83
85_R	120_E	0.840	0.83
218_C	248_P	0.837	0.82
23_K	76_T	0.836	0.82
355_R	358_R	0.833	0.82
428_T	473_I	0.828	0.82
342_P	417_Q	0.828	0.82
242_Q	249_V	0.826	0.82
194_V	206_A	0.825	0.82
361_E	418_E	0.825	0.82
240_A	244_K	0.824	0.81
100_I	431_G	0.822	0.81
465_S	501_Q	0.817	0.81
425_G	522_L	0.817	0.81
485_A	488_R	0.817	0.81
132_L	287_L	0.815	0.81
71_E	74_Q	0.814	0.81
145_V	167_M	0.813	0.81
495_A	528_A	0.812	0.81
334_L	506_L	0.810	0.80
142_D	166_S	0.810	0.80
119_A	125_L	0.808	0.80
466_E	470_G	0.806	0.80
211_L	245_H	0.805	0.80
124_E	286_A	0.805	0.80
473_I	479_A	0.803	0.80
238_I	249_V	0.803	0.80
150_G	193_D	0.802	0.80
164_R	285_D	0.801	0.80
232_T	265_V	0.801	0.80
2_S	55_Y	0.800	0.80
505_Q	509_D	0.798	0.79
472_M	500_I	0.794	0.79
368_I	372_D	0.793	0.79
100_I	452_E	0.792	0.79
204_R	208_D	0.790	0.79
496_I	521_L	0.790	0.79
210_V	213_D	0.788	0.79
97_T	150_G	0.788	0.79
6_A	148_N	0.788	0.79
44_A	74_Q	0.787	0.78
310_A	336_A	0.786	0.78
15_A	22_F	0.785	0.78
198_A	203_F	0.781	0.78
395_Y	398_L	0.780	0.78
86_T	162_D	0.777	0.78
308_R	312_R	0.776	0.77
507_V	513_I	0.776	0.77
65_F	116_V	0.776	0.77
311_A	333_L	0.775	0.77
95_S	98_G	0.775	0.77
41_Q	68_D	0.774	0.77
390_A	393_D	0.773	0.77
335_D	341_T	0.769	0.77
370_S	409_A	0.767	0.77
378_D	381_G	0.766	0.77
92_A	96_H	0.765	0.76
53_L	125_L	0.764	0.76
142_D	168_A	0.762	0.76
312_R	316_E	0.761	0.76
450_F	481_L	0.761	0.76
356_V	416_V	0.759	0.76
364_V	391_V	0.759	0.76
89_G	97_T	0.756	0.76
357_A	391_V	0.756	0.76
339_I	502_R	0.752	0.75
95_S	375_H	0.749	0.75
92_A	150_G	0.748	0.75
399_I	411_I	0.746	0.75
366_M	394_A	0.745	0.75
89_G	150_G	0.745	0.75
430_L	499_A	0.745	0.75
428_T	444_F	0.744	0.74
35_S	38_D	0.742	0.74
211_L	249_V	0.741	0.74
331_M	533_V	0.740	0.74
108_E	112_K	0.737	0.74
92_A	97_T	0.737	0.74
136_P	248_P	0.736	0.74
117_V	290_Q	0.732	0.73
368_I	398_L	0.731	0.73
90_A	94_S	0.730	0.73
355_R	359_D	0.730	0.73
505_Q	508_T	0.730	0.73
327_G	533_V	0.729	0.73
106_A	110_G	0.728	0.73
427_E	447_G	0.727	0.73
41_Q	44_A	0.725	0.73
306_V	338_G	0.724	0.72
299_Q	465_S	0.723	0.72
93_A	96_H	0.723	0.72
523_A	526_D	0.721	0.72
86_T	161_G	0.721	0.72
59_V	65_F	0.721	0.72
15_A	126_F	0.720	0.72
482_L	491_A	0.718	0.72
368_I	409_A	0.718	0.72
432_M	513_I	0.715	0.71
420_V	524_T	0.714	0.71
92_A	153_G	0.714	0.71
441_L	461_V	0.712	0.71
318_A	323_A	0.710	0.71
360_I	364_V	0.710	0.71
351_D	389_D	0.710	0.71
327_G	415_Q	0.709	0.71
146_I	206_A	0.708	0.71
339_I	506_L	0.707	0.71
474_D	497_T	0.706	0.71
444_F	523_A	0.706	0.71
82_K	158_D	0.704	0.70
331_M	341_T	0.704	0.70
28_L	31_K	0.703	0.70
44_A	52_I	0.698	0.70
463_P	469_A	0.698	0.70
368_I	399_I	0.696	0.69
521_L	528_A	0.693	0.69
261_Q	264_D	0.691	0.69
311_A	315_L	0.691	0.69
504_S	507_V	0.691	0.69
65_F	69_A	0.690	0.69
496_I	523_A	0.690	0.69
299_Q	302_T	0.689	0.69
95_S	99_T	0.688	0.69
451_V	519_N	0.687	0.68
496_I	499_A	0.684	0.68
375_H	451_V	0.683	0.68
150_G	154_V	0.683	0.68
442_L	504_S	0.682	0.68
470_G	493_E	0.682	0.68
358_R	388_T	0.682	0.68
346_V	413_G	0.682	0.68
460_R	469_A	0.681	0.68
464_V	504_S	0.680	0.68
96_H	102_G	0.679	0.68
237_V	241_L	0.679	0.68
407_P	411_I	0.679	0.68
8_I	33_V	0.678	0.67
318_A	329_E	0.678	0.67
97_T	375_H	0.678	0.67
240_A	243_E	0.678	0.67
325_R	329_E	0.678	0.67
340_P	499_A	0.677	0.67
101_A	443_L	0.677	0.67
2_S	8_I	0.677	0.67
146_I	207_I	0.676	0.67
352_A	356_V	0.676	0.67
324_T	374_L	0.673	0.67
207_I	238_I	0.668	0.66
40_M	72_V	0.668	0.66
93_A	150_G	0.665	0.66
96_H	517_D	0.665	0.66
102_G	150_G	0.664	0.66
62_G	110_G	0.664	0.66
347_V	357_A	0.662	0.66
523_A	528_A	0.662	0.66
370_S	413_G	0.660	0.65
96_H	452_E	0.658	0.65
481_L	484_G	0.658	0.65
341_T	530_A	0.655	0.65
332_D	335_D	0.653	0.65
344_G	415_Q	0.652	0.64
90_A	530_A	0.652	0.64
68_D	72_V	0.652	0.64
317_D	320_D	0.652	0.64
37_T	64_E	0.651	0.64
174_T	209_T	0.651	0.64
79_V	128_F	0.651	0.64
350_P	353_A	0.650	0.64
349_S	355_R	0.648	0.64
63_R	67_D	0.647	0.64
130_R	134_G	0.646	0.64
347_V	353_A	0.645	0.64
376_K	519_N	0.644	0.63
480_P	483_R	0.644	0.63
256_G	275_F	0.644	0.63
430_L	521_L	0.644	0.63
39_F	43_W	0.643	0.63
375_H	452_E	0.643	0.63
402_A	407_P	0.642	0.63
364_V	386_V	0.642	0.63
128_F	286_A	0.641	0.63
371_P	412_L	0.637	0.63
22_F	25_I	0.636	0.62
174_T	178_L	0.636	0.62
328_V	346_V	0.636	0.62
392_A	396_E	0.636	0.62
30_N	97_T	0.635	0.62
159_A	163_S	0.635	0.62
292_E	296_R	0.634	0.62
136_P	245_H	0.633	0.62
173_D	176_D	0.632	0.62
388_T	393_D	0.632	0.62
159_A	162_D	0.632	0.62
117_V	286_A	0.631	0.62
370_S	412_L	0.631	0.62
81_V	155_M	0.631	0.62
252_C	255_G	0.629	0.62
148_N	225_P	0.627	0.61
390_A	394_A	0.626	0.61
432_M	516_L	0.626	0.61
343_T	359_D	0.624	0.61
96_H	427_E	0.624	0.61
193_D	375_H	0.622	0.61
55_Y	83_S	0.622	0.61
431_G	519_N	0.621	0.61
8_I	196_G	0.621	0.61
100_I	429_I	0.621	0.61
354_R	364_V	0.621	0.61
22_F	49_T	0.618	0.60
331_M	342_P	0.617	0.60
41_Q	67_D	0.616	0.60
407_P	410_T	0.614	0.60
96_H	375_H	0.614	0.60
148_N	198_A	0.613	0.60
126_F	148_N	0.611	0.59
95_S	192_V	0.611	0.59
470_G	473_I	0.610	0.59
502_R	505_Q	0.610	0.59
91_Q	169_S	0.610	0.59
141_E	289_V	0.609	0.59
110_G	114_A	0.607	0.59
105_A	455_E	0.606	0.59
375_H	447_G	0.605	0.59
88_A	161_G	0.604	0.59
323_A	326_L	0.604	0.59
446_L	454_L	0.604	0.59
339_I	503_L	0.603	0.58
199_E	205_T	0.603	0.58
213_D	216_V	0.602	0.58
96_H	532_D	0.602	0.58
523_A	527_S	0.602	0.58
265_V	269_A	0.602	0.58
351_D	355_R	0.601	0.58
444_F	472_M	0.601	0.58
399_I	402_A	0.600	0.58
425_G	531_L	0.600	0.58
106_A	459_V	0.599	0.58
1_M	518_V	0.599	0.58
58_G	98_G	0.598	0.58
231_Y	277_P	0.598	0.58
89_G	154_V	0.597	0.58
373_I	402_A	0.596	0.58
368_I	379_I	0.596	0.58
376_K	427_E	0.595	0.57
85_R	104_E	0.595	0.57
6_A	196_G	0.595	0.57
356_V	361_E	0.594	0.57
132_L	301_P	0.594	0.57
51_V	129_A	0.594	0.57
367_K	427_E	0.591	0.57
199_E	202_R	0.590	0.57
97_T	193_D	0.590	0.57
463_P	504_S	0.590	0.57
276_D	279_R	0.589	0.57
163_S	282_G	0.589	0.57
433_N	517_D	0.588	0.57
92_A	98_G	0.588	0.57
174_T	215_H	0.588	0.57
364_V	419_M	0.588	0.57
445_G	457_T	0.587	0.56
18_Q	127_D	0.587	0.56
213_D	247_K	0.587	0.56
21_G	49_T	0.587	0.56
491_A	528_A	0.586	0.56
403_T	409_A	0.586	0.56
450_F	488_R	0.586	0.56
96_H	519_N	0.585	0.56
496_I	528_A	0.585	0.56
96_H	99_T	0.584	0.56
87_E	161_G	0.583	0.56
179_Q	187_N	0.583	0.56
373_I	409_A	0.582	0.56
181_S	206_A	0.582	0.56
434_R	514_L	0.581	0.56
519_N	532_D	0.581	0.56
44_A	76_T	0.581	0.56
91_Q	189_Y	0.580	0.56
220_L	250_V	0.578	0.55
180_G	205_T	0.578	0.55
237_V	495_A	0.578	0.55
337_Y	506_L	0.577	0.55
173_D	177_A	0.577	0.55
143_V	218_C	0.576	0.55
367_K	375_H	0.576	0.55
187_N	192_V	0.576	0.55
2_S	6_A	0.575	0.55
187_N	195_I	0.575	0.55
23_K	43_W	0.574	0.55
383_K	414_I	0.573	0.55
160_V	281_I	0.573	0.55
95_S	101_A	0.573	0.55
524_T	527_S	0.572	0.54
483_R	490_P	0.572	0.54
342_P	347_V	0.571	0.54
464_V	468_E	0.571	0.54
173_D	243_E	0.569	0.54
314_I	336_A	0.569	0.54
5_G	193_D	0.568	0.54
89_G	96_H	0.568	0.54
434_R	440_P	0.568	0.54
13_D	255_G	0.568	0.54
7_F	155_M	0.566	0.54
5_G	97_T	0.566	0.54
342_P	418_E	0.566	0.54
481_L	488_R	0.563	0.53
6_A	55_Y	0.563	0.53
375_H	378_D	0.563	0.53
10_A	25_I	0.562	0.53
453_I	484_G	0.560	0.53
58_G	99_T	0.560	0.53
8_I	27_S	0.559	0.53
232_T	261_Q	0.559	0.53
450_F	453_I	0.559	0.53
492_D	524_T	0.559	0.53
1_M	39_F	0.559	0.53
425_G	527_S	0.558	0.53
8_I	56_L	0.558	0.53
501_Q	504_S	0.558	0.53
343_T	360_I	0.558	0.53
35_S	64_E	0.558	0.53
481_L	485_A	0.557	0.53
255_G	277_P	0.557	0.53
131_A	250_V	0.557	0.53
312_R	315_L	0.556	0.52
444_F	500_I	0.556	0.52
462_A	508_T	0.555	0.52
516_L	535_L	0.554	0.52
128_F	283_S	0.553	0.52
447_G	532_D	0.553	0.52
399_I	403_T	0.552	0.52
299_Q	467_R	0.552	0.52
450_F	454_L	0.552	0.52
375_H	532_D	0.552	0.52
420_V	531_L	0.552	0.52
442_L	472_M	0.551	0.52
291_R	295_S	0.551	0.52
64_E	67_D	0.551	0.52
431_G	443_L	0.550	0.52
95_S	431_G	0.550	0.52
362_G	386_V	0.550	0.52
33_V	274_Y	0.549	0.52
150_G	519_N	0.549	0.52
28_L	39_F	0.548	0.51
469_A	473_I	0.547	0.51
96_H	193_D	0.546	0.51
4_S	55_Y	0.546	0.51
403_T	408_D	0.545	0.51
41_Q	70_R	0.544	0.51
242_Q	245_H	0.543	0.51
93_A	97_T	0.543	0.51
143_V	220_L	0.542	0.51
349_S	353_A	0.542	0.51
204_R	241_L	0.542	0.51
431_G	447_G	0.541	0.50
243_E	269_A	0.540	0.50
58_G	95_S	0.540	0.50
110_G	438_F	0.539	0.50
434_R	511_P	0.537	0.50
286_A	289_V	0.537	0.50
97_T	519_N	0.536	0.50
499_A	530_A	0.536	0.50
51_V	284_L	0.536	0.50
89_G	102_G	0.536	0.50
57_E	375_H	0.534	0.50
63_R	339_I	0.534	0.50
448_G	519_N	0.533	0.49
403_T	411_I	0.532	0.49
98_G	452_E	0.532	0.49
117_V	293_V	0.531	0.49
95_S	449_I	0.531	0.49
52_I	68_D	0.530	0.49
5_G	431_G	0.530	0.49
272_P	352_A	0.529	0.49
403_T	407_P	0.529	0.49
40_M	500_I	0.529	0.49
351_D	400_T	0.528	0.49
144_A	168_A	0.528	0.49
149_A	231_Y	0.528	0.49
170_F	288_A	0.528	0.49
360_I	363_D	0.527	0.49
416_V	471_D	0.527	0.49
9_T	224_A	0.526	0.49
62_G	438_F	0.526	0.49
303_A	349_S	0.526	0.49
6_A	152_P	0.526	0.49
515_E	534_Q	0.524	0.48
485_A	489_D	0.523	0.48
480_P	485_A	0.523	0.48
149_A	228_V	0.523	0.48
124_E	332_D	0.522	0.48
23_K	48_D	0.521	0.48
183_P	195_I	0.520	0.48
70_R	73_T	0.520	0.48
122_V	155_M	0.520	0.48
371_P	411_I	0.519	0.48
9_T	148_N	0.519	0.48
454_L	477_D	0.519	0.48
378_D	449_I	0.519	0.48
401_R	404_N	0.519	0.48
106_A	438_F	0.518	0.48
333_L	513_I	0.518	0.48
220_L	281_I	0.517	0.47
378_D	382_V	0.517	0.47
370_S	379_I	0.517	0.47
145_V	156_A	0.517	0.47
117_V	132_L	0.516	0.47
308_R	337_Y	0.516	0.47
174_T	210_V	0.515	0.47
377_S	427_E	0.515	0.47
232_T	236_G	0.515	0.47
268_D	316_E	0.514	0.47
196_G	202_R	0.514	0.47
328_V	369_V	0.514	0.47
356_V	360_I	0.513	0.47
209_T	213_D	0.513	0.47
93_A	98_G	0.513	0.47
524_T	529_T	0.513	0.47
317_D	332_D	0.512	0.47
101_A	459_V	0.512	0.47
210_V	219_A	0.512	0.47
100_I	457_T	0.509	0.46
31_K	534_Q	0.509	0.46
160_V	259_T	0.509	0.46
94_S	98_G	0.509	0.46
87_E	365_V	0.509	0.46
89_G	101_A	0.508	0.46
46_D	76_T	0.508	0.46
173_D	214_E	0.508	0.46
101_A	431_G	0.507	0.46
223_S	226_T	0.506	0.46
442_L	507_V	0.505	0.46
72_V	149_A	0.505	0.46
156_A	280_A	0.505	0.46
443_L	517_D	0.504	0.46
43_W	49_T	0.503	0.46
144_A	213_D	0.503	0.46
460_R	464_V	0.503	0.46
144_A	170_F	0.503	0.46
456_D	482_L	0.503	0.46
387_E	393_D	0.502	0.45
375_H	427_E	0.502	0.45
489_D	526_D	0.502	0.45
153_G	197_D	0.501	0.45
353_A	362_G	0.501	0.45
338_G	502_R	0.501	0.45
173_D	393_D	0.501	0.45
178_L	182_M	0.501	0.45
111_F	461_V	0.500	0.45
167_M	217_G	0.500	0.45

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
2csuA	2	0.5129	100	0.541	Contact Map
3dmyA	2	0.5775	100	0.6	Contact Map
3mwdA	2	0.3893	100	0.741	Contact Map
3pffA	2	0.393	100	0.743	Contact Map
1wr2A	1	0.4244	100	0.746	Contact Map
3mwdB	1	0.2528	100	0.762	Contact Map
2fp4B	1	0.3819	100	0.776	Contact Map
2nu8B	2	0.3801	100	0.778	Contact Map
3ufxB	2	0.3727	100	0.784	Contact Map
2fp4A	1	0.2528	100	0.789	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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