GREMLIN Database
Q9HQY8 - Chemotaxis protein
UniProt: Q9HQY8 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 132 (126)
Sequences: 4445 (3100)
Seq/√Len: 276.1

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
17_R121_R3.5951.00
104_D117_R3.2851.00
76_I86_G2.8731.00
7_D97_A2.8061.00
27_E52_R2.8061.00
98_V116_I2.6771.00
46_I60_D2.5731.00
46_I63_V2.5131.00
26_D80_S2.4551.00
24_H129_D2.4461.00
103_L114_G2.2691.00
46_I88_L2.2391.00
12_S91_D2.2241.00
99_G102_A2.1211.00
62_R90_D2.0821.00
79_L87_L2.0571.00
31_A35_V1.9111.00
50_D53_G1.8651.00
113_R127_E1.8451.00
63_V69_G1.7661.00
71_A74_T1.7561.00
110_E130_A1.6741.00
58_V76_I1.6701.00
6_T21_D1.6301.00
118_R121_R1.5651.00
50_D55_T1.5561.00
54_E84_A1.5481.00
30_D75_R1.5411.00
31_A88_L1.4931.00
6_T100_E1.4841.00
112_T124_V1.4411.00
12_S93_H1.4351.00
26_D54_E1.4321.00
17_R93_H1.4301.00
21_D113_R1.4141.00
10_E17_R1.4131.00
103_L125_W1.3941.00
14_G62_R1.3501.00
43_Q63_V1.3421.00
58_V86_G1.3421.00
21_D24_H1.3251.00
31_A76_I1.3051.00
8_V125_W1.2801.00
56_T78_V1.2791.00
8_V116_I1.2791.00
9_L75_R1.2141.00
102_A118_R1.2131.00
5_E97_A1.2011.00
26_D84_A1.1791.00
60_D63_V1.1721.00
9_L77_V1.1641.00
49_V76_I1.1561.00
20_I79_L1.1371.00
25_V77_V1.1041.00
127_E130_A1.0551.00
10_E93_H1.0411.00
61_P87_L1.0201.00
12_S15_A1.0081.00
10_E96_E1.0041.00
87_L128_P0.9991.00
81_D129_D0.9951.00
60_D69_G0.9921.00
8_V98_V0.9841.00
118_R123_V0.9631.00
32_G76_I0.9501.00
11_F77_V0.9501.00
20_I128_P0.9241.00
29_V76_I0.9221.00
32_G35_V0.9141.00
116_I125_W0.9121.00
6_T113_R0.9111.00
61_P131_L0.9101.00
44_H64_K0.9041.00
35_V58_V0.8961.00
24_H113_R0.8831.00
62_R67_E0.8761.00
5_E100_E0.8651.00
51_L78_V0.8641.00
19_C116_I0.8491.00
60_D64_K0.8491.00
24_H128_P0.8451.00
19_C123_V0.8311.00
29_V51_L0.8220.99
14_G67_E0.8180.99
31_A75_R0.8140.99
45_V57_T0.8090.99
106_S112_T0.7990.99
49_V58_V0.7980.99
79_L128_P0.7940.99
74_T88_L0.7780.99
77_V89_V0.7750.99
96_E121_R0.7690.99
76_I88_L0.7690.99
9_L28_I0.7680.99
5_E99_G0.7670.99
29_V32_G0.7660.99
15_A101_A0.7660.99
12_S17_R0.7470.99
13_L61_P0.7440.99
30_D122_F0.7410.99
27_E92_V0.7380.99
64_K107_A0.7210.99
35_V49_V0.7190.99
19_C125_W0.7180.99
12_S96_E0.7130.99
36_T50_D0.7060.98
115_I122_F0.7030.98
11_F65_L0.7020.98
9_L25_V0.6890.98
40_N43_Q0.6880.98
74_T90_D0.6870.98
98_V103_L0.6850.98
22_I29_V0.6850.98
20_I25_V0.6830.98
109_S130_A0.6770.98
27_E51_L0.6760.98
114_G125_W0.6750.98
67_E70_A0.6650.98
62_R68_D0.6630.98
38_I48_V0.6610.98
10_E94_E0.6600.98
38_I104_D0.6550.97
64_K111_T0.6510.97
79_L131_L0.6480.97
60_D70_A0.6470.97
44_H63_V0.6430.97
11_F20_I0.6400.97
9_L115_I0.6380.97
8_V100_E0.6350.97
7_D22_I0.6340.97
82_H101_A0.6330.97
29_V92_V0.6310.97
43_Q100_E0.6300.97
117_R122_F0.6290.97
38_I41_S0.6290.97
62_R69_G0.6270.97
31_A74_T0.6250.97
11_F27_E0.6190.96
13_L85_T0.6170.96
70_A90_D0.6140.96
46_I69_G0.6100.96
18_Y65_L0.6020.96
49_V78_V0.5960.96
29_V49_V0.5960.96
36_T39_P0.5940.95
124_V127_E0.5930.95
72_D83_D0.5920.95
35_V51_L0.5910.95
9_L30_D0.5830.95
56_T84_A0.5820.95
48_V124_V0.5780.95
80_S84_A0.5750.95
38_I55_T0.5740.95
32_G56_T0.5690.94
39_P45_V0.5680.94
13_L111_T0.5670.94
41_S45_V0.5650.94
69_G102_A0.5610.94
71_A75_R0.5600.94
71_A90_D0.5570.94
18_Y25_V0.5560.94
102_A117_R0.5530.93
69_G110_E0.5490.93
57_T74_T0.5490.93
5_E23_A0.5480.93
15_A70_A0.5420.93
28_I50_D0.5420.93
32_G49_V0.5400.93
55_T77_V0.5400.93
35_V76_I0.5390.93
97_A100_E0.5380.92
38_I50_D0.5370.92
17_R123_V0.5370.92
45_V59_V0.5360.92
8_V19_C0.5310.92
36_T55_T0.5270.92
66_G109_S0.5270.92
29_V54_E0.5270.92
57_T64_K0.5230.91
37_P130_A0.5230.91
38_I53_G0.5200.91
48_V115_I0.5150.91
23_A26_D0.5120.91
10_E123_V0.5110.90
90_D95_V0.5080.90
75_R91_D0.5060.90
40_N93_H0.5060.90
55_T124_V0.5030.90
9_L29_V0.5000.90
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
2ho9A 1 0.9924 99.9 0.207 Contact Map
4jpbW 1 0.9697 99.9 0.216 Contact Map
2qdlA 1 0.9924 99.9 0.218 Contact Map
1b3qA 2 0.9545 99.3 0.555 Contact Map
1zq1A 2 0.8182 7.3 0.921 Contact Map
4o0aA 1 0.7197 6.9 0.922 Contact Map
1rqbA 2 0 5 0.927 Contact Map
2xheA 1 0.3864 4.8 0.928 Contact Map
3shqA 1 0.8788 4.3 0.929 Contact Map
3ll7A 1 0.6742 4.1 0.93 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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