Q9HQY3 - HALSA - GREMLIN Contacts

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Q9HQY3 - Type II secretion system protein

UniProt:	Q9HQY3	Sequences: MADHGSRQIGHELRETATRYTHLQEYLQRFKQFTGEFPELIDEPTDDWEADKPNVVYPVGGPIFCHVYGDLGKDTKYYTIEPELSGPEAAVFKNVQERILEKSVNKPAPEAEAEYDDRIEELLEETVRISDDKSDDVFHRVRQLPNNLGSLVKNFDASTVADRMVGDDRGQMSLDSGDLSAQQMRAGARRVASSPRNAINRVQRAVPMVREALEEAFGFGRIPVSETTYENIRYQLNRDIVGFGPLEPVMRDPYNEDIHVIGPTGCYVDHGTYGMLETTVDFGTPDEFDGWLRNMGERMGDPVSDSDPIVDSTLPDGSRINIIYSDDVSLKGPSLTIRQGDDVPLSVGQITKWGTLSPELAAYLWLCLENEQTVFVVGETASGKTTTLNSIMSFIPRDSKIYTAEDTAEVIPPHDTWQQLLTREGQGENSADVDMFDLVAAALRSRPDYIIVGEVRGEEGRMAFQAAQTGHPVMLTFHASDIVSMIQRFTGEPINVPETFMDNADVALFQNRVKQGDDVLRRVTSVQEIEGYSKEMGGVVTRQAFYWDPVEDEIVFQGRNNSFVLEEQIATLLGYADTREIYDEMDFRAEILERIIQEDLIGYHDFNDTIAAFQRDGVEGLPFTISRGF	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	629 (492)
Sequences:	2291 (1690)
Seq/√Len:	76.2

ECOLI - GSPE HOFB
HALSA - Q9HQY3 Q9HR79
SULSO - Q97VE6 Q97WB7

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
548_D	573_L	5.945	1.00
363_Y	391_I	4.707	1.00
516_G	591_I	4.329	1.00
334_S	400_K	4.021	1.00
481_D	484_S	3.952	1.00
292_L	335_L	3.942	1.00
163_R	167_D	3.759	1.00
554_I	569_I	3.673	1.00
366_L	506_V	3.630	1.00
117_D	125_E	3.475	1.00
554_I	559_R	3.416	1.00
402_Y	442_A	3.369	1.00
204_R	209_V	3.046	1.00
395_I	449_Y	3.036	1.00
404_A	438_L	3.022	1.00
551_E	565_L	2.815	1.00
308_P	424_E	2.803	1.00
364_L	394_F	2.801	1.00
516_G	521_R	2.795	1.00
101_E	104_V	2.761	1.00
580_E	584_E	2.756	1.00
191_V	199_I	2.706	1.00
581_I	595_I	2.668	1.00
330_L	408_A	2.667	1.00
508_L	544_A	2.665	1.00
571_T	579_R	2.592	1.00
327_D	418_Q	2.585	1.00
129_I	134_S	2.582	1.00
318_S	341_D	2.565	1.00
550_V	573_L	2.564	1.00
539_V	589_A	2.536	1.00
275_M	597_Q	2.526	1.00
455_V	464_F	2.497	1.00
569_I	573_L	2.493	1.00
515_Q	539_V	2.481	1.00
100_L	105_N	2.468	1.00
301_D	326_D	2.413	1.00
399_S	449_Y	2.380	1.00
377_V	477_F	2.324	1.00
569_I	572_L	2.289	1.00
547_W	555_V	2.280	1.00
548_D	569_I	2.271	1.00
360_L	364_L	2.266	1.00
326_D	335_L	2.262	1.00
130_S	133_K	2.254	1.00
266_C	288_F	2.187	1.00
334_S	416_T	2.185	1.00
120_E	140_R	2.181	1.00
278_T	281_D	2.168	1.00
102_K	106_K	2.140	1.00
139_H	145_P	2.130	1.00
322_I	337_I	2.113	1.00
375_F	475_L	2.081	1.00
246_L	291_W	2.073	1.00
176_S	197_N	2.064	1.00
358_P	576_A	2.061	1.00
359_E	542_R	2.055	1.00
299_M	324_Y	2.029	1.00
131_D	207_P	2.024	1.00
367_C	391_I	1.980	1.00
583_D	587_F	1.969	1.00
109_P	112_E	1.966	1.00
184_M	204_R	1.946	1.00
396_P	401_I	1.944	1.00
486_I	504_A	1.925	1.00
576_A	583_D	1.919	1.00
165_V	169_R	1.918	1.00
490_T	500_F	1.916	1.00
254_Y	536_M	1.887	1.00
320_I	339_Q	1.870	1.00
122_L	126_T	1.868	1.00
582_Y	586_D	1.864	1.00
550_V	572_L	1.863	1.00
180_S	200_N	1.862	1.00
205_A	208_M	1.857	1.00
421_L	424_E	1.849	1.00
483_V	545_F	1.846	1.00
325_S	445_S	1.842	1.00
174_L	202_V	1.819	1.00
182_Q	202_V	1.802	1.00
322_I	339_Q	1.800	1.00
355_T	387_T	1.783	1.00
559_R	564_V	1.764	1.00
108_A	112_E	1.756	1.00
395_I	474_M	1.747	1.00
135_D	203_Q	1.744	1.00
329_S	416_T	1.735	1.00
117_D	122_L	1.728	1.00
585_M	595_I	1.721	1.00
181_A	184_M	1.716	1.00
418_Q	442_A	1.704	1.00
361_A	365_W	1.691	1.00
365_W	546_Y	1.668	1.00
359_E	544_A	1.665	1.00
404_A	442_A	1.655	1.00
553_E	557_Q	1.649	1.00
172_M	209_V	1.629	1.00
356_L	359_E	1.623	1.00
183_Q	191_V	1.617	1.00
275_M	514_K	1.610	1.00
366_L	544_A	1.590	0.99
340_G	410_V	1.584	0.99
108_A	119_I	1.583	0.99
551_E	569_I	1.572	0.99
359_E	580_E	1.557	0.99
568_Q	572_L	1.550	0.99
578_T	599_D	1.543	0.99
517_D	530_E	1.542	0.99
462_M	465_Q	1.541	0.99
367_C	374_V	1.536	0.99
545_F	575_Y	1.526	0.99
517_D	520_L	1.525	0.99
483_V	565_L	1.524	0.99
166_G	213_L	1.519	0.99
188_A	201_R	1.506	0.99
167_D	214_E	1.503	0.99
272_T	277_E	1.501	0.99
560_N	564_V	1.498	0.99
147_N	208_M	1.498	0.99
334_S	402_Y	1.491	0.99
185_R	201_R	1.488	0.99
520_L	530_E	1.485	0.99
109_P	120_E	1.482	0.99
500_F	504_A	1.478	0.99
104_V	128_R	1.467	0.99
133_K	136_D	1.453	0.99
170_G	210_R	1.448	0.99
481_D	567_E	1.443	0.99
571_T	577_D	1.441	0.99
374_V	472_P	1.439	0.99
374_V	506_V	1.438	0.99
455_V	475_L	1.433	0.99
260_V	266_C	1.426	0.99
357_S	361_A	1.417	0.99
314_L	322_I	1.411	0.99
250_M	258_I	1.411	0.99
557_Q	564_V	1.401	0.99
171_Q	191_V	1.393	0.99
261_I	269_D	1.392	0.99
465_Q	491_G	1.391	0.99
121_E	206_V	1.387	0.99
265_G	281_D	1.365	0.98
368_L	394_F	1.364	0.98
438_L	442_A	1.356	0.98
111_A	114_E	1.354	0.98
112_E	120_E	1.353	0.98
308_P	433_V	1.346	0.98
249_V	258_I	1.340	0.98
175_D	182_Q	1.332	0.98
371_E	505_D	1.323	0.98
267_Y	278_T	1.320	0.98
298_R	314_L	1.313	0.98
570_A	574_G	1.308	0.98
255_N	272_T	1.306	0.98
118_R	140_R	1.302	0.98
295_M	324_Y	1.299	0.98
104_V	107_P	1.298	0.98
519_V	536_M	1.295	0.98
131_D	135_D	1.293	0.98
107_P	110_E	1.293	0.98
325_S	336_T	1.292	0.98
351_T	360_L	1.289	0.98
564_V	568_Q	1.281	0.98
166_G	217_F	1.273	0.98
319_R	342_D	1.268	0.97
174_L	184_M	1.265	0.97
513_V	590_E	1.263	0.97
436_F	459_E	1.244	0.97
483_V	567_E	1.242	0.97
541_T	581_I	1.235	0.97
495_N	498_E	1.226	0.97
135_D	205_A	1.221	0.97
299_M	314_L	1.221	0.97
539_V	584_E	1.215	0.97
358_P	362_A	1.215	0.97
375_F	455_V	1.210	0.97
172_M	212_A	1.208	0.97
139_H	143_Q	1.205	0.97
107_P	111_A	1.204	0.96
161_A	166_G	1.194	0.96
461_R	494_I	1.194	0.96
302_P	423_R	1.190	0.96
108_A	123_L	1.189	0.96
169_R	187_G	1.188	0.96
468_Q	499_T	1.186	0.96
434_D	437_D	1.186	0.96
135_D	145_P	1.185	0.96
535_E	590_E	1.181	0.96
518_D	521_R	1.179	0.96
362_A	546_Y	1.176	0.96
120_E	138_F	1.176	0.96
112_E	122_L	1.166	0.96
181_A	185_R	1.163	0.96
170_G	206_V	1.154	0.96
285_P	288_F	1.154	0.96
250_M	322_I	1.153	0.96
111_A	126_T	1.145	0.95
581_I	584_E	1.143	0.95
513_V	539_V	1.138	0.95
550_V	569_I	1.135	0.95
487_Q	562_S	1.133	0.95
206_V	210_R	1.127	0.95
246_L	295_M	1.112	0.95
301_D	325_S	1.112	0.95
349_Q	352_K	1.108	0.94
108_A	111_A	1.102	0.94
180_S	198_A	1.099	0.94
146_N	174_L	1.099	0.94
184_M	202_V	1.087	0.94
105_N	119_I	1.086	0.94
404_A	418_Q	1.082	0.94
111_A	115_Y	1.080	0.94
359_E	508_L	1.076	0.94
263_P	267_Y	1.074	0.93
136_D	145_P	1.065	0.93
275_M	398_D	1.063	0.93
108_A	122_L	1.057	0.93
570_A	575_Y	1.046	0.93
211_E	215_E	1.041	0.92
325_S	441_A	1.041	0.92
135_D	139_H	1.039	0.92
112_E	118_R	1.030	0.92
373_T	506_V	1.027	0.92
359_E	362_A	1.027	0.92
404_A	420_L	1.027	0.92
541_T	598_E	1.025	0.92
350_I	390_S	1.012	0.91
107_P	128_R	1.003	0.91
165_V	194_S	1.001	0.91
112_E	115_Y	0.999	0.91
543_Q	575_Y	0.998	0.91
514_K	594_R	0.995	0.91
117_D	121_E	0.992	0.90
371_E	481_D	0.991	0.90
549_P	552_D	0.984	0.90
288_F	292_L	0.980	0.90
158_S	216_A	0.974	0.90
535_E	591_I	0.968	0.89
217_F	223_P	0.968	0.89
458_E	462_M	0.966	0.89
131_D	205_A	0.965	0.89
355_T	542_R	0.964	0.89
334_S	445_S	0.964	0.89
350_I	364_L	0.961	0.89
270_H	279_T	0.961	0.89
129_I	133_K	0.960	0.89
369_E	505_D	0.956	0.89
465_Q	468_Q	0.956	0.89
129_I	137_V	0.953	0.89
385_T	389_N	0.950	0.88
308_P	432_D	0.947	0.88
553_E	568_Q	0.942	0.88
363_Y	544_A	0.938	0.88
157_A	160_V	0.937	0.88
109_P	140_R	0.937	0.88
217_F	220_G	0.933	0.87
356_L	587_F	0.929	0.87
376_V	508_L	0.927	0.87
392_M	415_D	0.924	0.87
241_V	244_G	0.923	0.87
439_V	463_A	0.919	0.87
112_E	127_V	0.912	0.86
177_G	181_A	0.912	0.86
123_L	129_I	0.912	0.86
485_M	507_A	0.908	0.86
523_V	526_V	0.908	0.86
567_E	571_T	0.906	0.86
380_T	471_H	0.903	0.86
160_V	176_S	0.902	0.86
516_G	523_V	0.899	0.85
246_L	484_S	0.898	0.85
541_T	599_D	0.898	0.85
356_L	583_D	0.893	0.85
324_Y	337_I	0.890	0.85
542_R	580_E	0.887	0.85
219_F	223_P	0.884	0.84
571_T	575_Y	0.884	0.84
195_P	198_A	0.883	0.84
320_I	341_D	0.883	0.84
377_V	509_F	0.880	0.84
301_D	335_L	0.879	0.84
153_K	157_A	0.874	0.84
483_V	575_Y	0.868	0.83
434_D	459_E	0.863	0.83
356_L	580_E	0.860	0.83
174_L	182_Q	0.859	0.83
156_D	159_T	0.857	0.83
313_T	321_N	0.857	0.83
108_A	126_T	0.854	0.82
146_N	204_R	0.854	0.82
161_A	173_S	0.853	0.82
171_Q	187_G	0.851	0.82
481_D	543_Q	0.849	0.82
521_R	591_I	0.849	0.82
178_D	181_A	0.845	0.82
365_W	369_E	0.841	0.81
571_T	574_G	0.840	0.81
103_S	106_K	0.839	0.81
433_V	441_A	0.837	0.81
377_V	467_A	0.836	0.81
507_A	545_F	0.835	0.81
450_I	466_A	0.832	0.81
387_T	508_L	0.832	0.81
120_E	124_E	0.828	0.80
220_G	223_P	0.826	0.80
218_G	223_P	0.819	0.80
169_R	190_R	0.818	0.80
192_A	198_A	0.817	0.79
462_M	495_N	0.815	0.79
422_T	434_D	0.811	0.79
254_Y	272_T	0.810	0.79
266_C	291_W	0.809	0.79
422_T	433_V	0.809	0.79
396_P	414_H	0.809	0.79
442_A	450_I	0.808	0.79
433_V	438_L	0.807	0.79
105_N	112_E	0.807	0.79
228_T	234_Y	0.807	0.79
355_T	540_V	0.803	0.78
582_Y	592_L	0.802	0.78
139_H	203_Q	0.801	0.78
355_T	363_Y	0.801	0.78
501_M	556_F	0.799	0.78
545_F	565_L	0.799	0.78
278_T	397_R	0.796	0.78
112_E	116_D	0.794	0.78
321_N	389_N	0.792	0.77
327_D	445_S	0.792	0.77
219_F	222_I	0.791	0.77
380_T	469_T	0.791	0.77
373_T	505_D	0.789	0.77
153_K	162_D	0.788	0.77
228_T	231_N	0.788	0.77
262_G	489_F	0.786	0.77
582_Y	595_I	0.786	0.77
358_P	583_D	0.784	0.77
416_T	445_S	0.782	0.76
516_G	522_R	0.782	0.76
385_T	412_P	0.782	0.76
515_Q	519_V	0.781	0.76
295_M	326_D	0.780	0.76
455_V	461_R	0.775	0.76
424_E	468_Q	0.775	0.76
228_T	232_I	0.774	0.76
385_T	390_S	0.772	0.76
112_E	140_R	0.772	0.76
366_L	374_V	0.764	0.75
404_A	411_I	0.764	0.75
341_D	412_P	0.763	0.75
350_I	360_L	0.763	0.75
443_L	466_A	0.763	0.75
256_E	336_T	0.760	0.74
485_M	499_T	0.757	0.74
182_Q	200_N	0.756	0.74
442_A	452_V	0.756	0.74
130_S	137_V	0.752	0.74
146_N	212_A	0.752	0.74
239_D	595_I	0.751	0.74
181_A	195_P	0.751	0.74
179_L	197_N	0.749	0.73
210_R	214_E	0.749	0.73
294_N	298_R	0.747	0.73
118_R	203_Q	0.747	0.73
205_A	209_V	0.745	0.73
185_R	188_A	0.744	0.73
342_D	410_V	0.744	0.73
581_I	590_E	0.744	0.73
584_E	589_A	0.742	0.73
408_A	543_Q	0.742	0.73
197_N	201_R	0.742	0.73
120_E	123_L	0.741	0.73
380_T	447_P	0.741	0.73
176_S	179_L	0.739	0.72
479_A	482_I	0.738	0.72
139_H	144_L	0.737	0.72
160_V	166_G	0.737	0.72
186_A	190_R	0.735	0.72
261_I	306_S	0.734	0.72
212_A	217_F	0.733	0.72
522_R	525_S	0.732	0.72
484_S	499_T	0.732	0.72
486_I	555_V	0.729	0.71
594_R	597_Q	0.726	0.71
583_D	586_D	0.724	0.71
168_D	356_L	0.723	0.71
243_F	294_N	0.721	0.70
105_N	108_A	0.720	0.70
238_R	443_L	0.717	0.70
404_A	463_A	0.714	0.70
105_N	120_E	0.712	0.70
124_E	134_S	0.711	0.69
184_M	209_V	0.711	0.69
287_E	291_W	0.711	0.69
209_V	213_L	0.710	0.69
424_E	437_D	0.709	0.69
266_C	292_L	0.709	0.69
515_Q	589_A	0.708	0.69
111_A	122_L	0.707	0.69
127_V	131_D	0.705	0.69
366_L	505_D	0.704	0.69
273_Y	514_K	0.704	0.69
148_L	184_M	0.703	0.69
336_T	445_S	0.702	0.68
454_E	478_H	0.700	0.68
171_Q	183_Q	0.698	0.68
432_D	437_D	0.698	0.68
345_L	385_T	0.698	0.68
166_G	452_V	0.696	0.68
461_R	489_F	0.695	0.68
497_P	558_G	0.691	0.67
377_V	479_A	0.690	0.67
302_P	308_P	0.686	0.67
100_L	104_V	0.686	0.67
124_E	127_V	0.685	0.67
240_I	297_E	0.683	0.66
254_Y	319_R	0.681	0.66
444_R	456_R	0.680	0.66
363_Y	374_V	0.680	0.66
313_T	411_I	0.680	0.66
179_L	182_Q	0.677	0.66
301_D	308_P	0.677	0.66
293_R	342_D	0.676	0.66
254_Y	513_V	0.675	0.65
444_R	478_H	0.675	0.65
162_D	165_V	0.673	0.65
157_A	176_S	0.673	0.65
554_I	564_V	0.671	0.65
490_T	558_G	0.671	0.65
370_N	480_S	0.670	0.65
158_S	173_S	0.668	0.65
106_K	110_E	0.668	0.65
356_L	584_E	0.667	0.64
389_N	412_P	0.665	0.64
118_R	121_E	0.662	0.64
189_R	195_P	0.662	0.64
400_K	445_S	0.659	0.64
555_V	565_L	0.658	0.63
160_V	195_P	0.658	0.63
513_V	581_I	0.655	0.63
179_L	198_A	0.655	0.63
409_E	478_H	0.652	0.63
356_L	542_R	0.651	0.63
444_R	488_R	0.650	0.62
592_L	596_I	0.650	0.62
331_K	411_I	0.650	0.62
352_K	390_S	0.649	0.62
495_N	558_G	0.648	0.62
309_I	460_G	0.648	0.62
154_N	157_A	0.648	0.62
138_F	203_Q	0.647	0.62
445_S	465_Q	0.647	0.62
311_D	325_S	0.647	0.62
490_T	497_P	0.647	0.62
551_E	570_A	0.647	0.62
321_N	410_V	0.646	0.62
338_R	478_H	0.646	0.62
154_N	176_S	0.645	0.62
216_A	220_G	0.645	0.62
297_E	390_S	0.644	0.62
190_R	193_S	0.643	0.62
384_K	454_E	0.643	0.62
275_M	598_E	0.643	0.62
591_I	594_R	0.641	0.61
133_K	137_V	0.641	0.61
367_C	474_M	0.641	0.61
119_I	123_L	0.641	0.61
466_A	501_M	0.641	0.61
165_V	168_D	0.640	0.61
446_R	538_G	0.640	0.61
373_T	465_Q	0.638	0.61
226_E	229_Y	0.638	0.61
230_E	551_E	0.637	0.61
149_G	211_E	0.637	0.61
144_L	202_V	0.636	0.61
302_P	524_T	0.634	0.61
303_V	468_Q	0.632	0.60
229_Y	232_I	0.629	0.60
132_D	205_A	0.629	0.60
391_I	404_A	0.628	0.60
153_K	172_M	0.628	0.60
147_N	150_S	0.627	0.60
318_S	343_V	0.626	0.60
468_Q	595_I	0.625	0.59
307_D	473_V	0.624	0.59
161_A	171_Q	0.623	0.59
141_V	166_G	0.622	0.59
303_V	307_D	0.622	0.59
148_L	151_L	0.622	0.59
243_F	246_L	0.621	0.59
191_V	195_P	0.620	0.59
297_E	334_S	0.618	0.59
144_L	295_M	0.617	0.58
109_P	113_A	0.615	0.58
235_Q	238_R	0.610	0.58
449_Y	505_D	0.610	0.58
506_V	544_A	0.609	0.57
115_Y	122_L	0.609	0.57
469_T	478_H	0.608	0.57
189_R	498_E	0.607	0.57
279_T	374_V	0.606	0.57
240_I	500_F	0.606	0.57
456_R	488_R	0.606	0.57
437_D	441_A	0.604	0.57
109_P	138_F	0.604	0.57
110_E	113_A	0.604	0.57
103_S	107_P	0.604	0.57
567_E	577_D	0.602	0.57
385_T	410_V	0.601	0.57
439_V	451_I	0.600	0.56
386_T	410_V	0.599	0.56
108_A	113_A	0.599	0.56
504_A	507_A	0.599	0.56
477_F	485_M	0.598	0.56
218_G	222_I	0.598	0.56
136_D	139_H	0.598	0.56
545_F	577_D	0.597	0.56
151_L	174_L	0.596	0.56
315_P	322_I	0.596	0.56
502_D	506_V	0.596	0.56
122_L	128_R	0.595	0.56
233_R	236_L	0.594	0.56
410_V	499_T	0.594	0.56
350_I	468_Q	0.594	0.56
187_G	191_V	0.594	0.56
554_I	565_L	0.593	0.56
229_Y	233_R	0.592	0.55
402_Y	410_V	0.592	0.55
155_F	159_T	0.592	0.55
380_T	456_R	0.591	0.55
237_N	243_F	0.591	0.55
132_D	532_Y	0.591	0.55
254_Y	288_F	0.590	0.55
249_V	268_V	0.589	0.55
373_T	473_V	0.589	0.55
483_V	562_S	0.588	0.55
418_Q	438_L	0.588	0.55
167_D	335_L	0.588	0.55
134_S	137_V	0.587	0.55
132_D	145_P	0.587	0.55
451_I	492_E	0.587	0.55
447_P	471_H	0.586	0.55
179_L	184_M	0.586	0.55
424_E	433_V	0.584	0.54
559_R	565_L	0.584	0.54
395_I	399_S	0.583	0.54
277_E	531_G	0.583	0.54
269_D	445_S	0.582	0.54
589_A	595_I	0.579	0.54
457_G	460_G	0.578	0.54
121_E	306_S	0.576	0.53
338_R	384_K	0.575	0.53
245_P	291_W	0.575	0.53
447_P	469_T	0.574	0.53
254_Y	503_N	0.573	0.53
559_R	569_I	0.573	0.53
314_L	324_Y	0.573	0.53
477_F	482_I	0.573	0.53
374_V	434_D	0.571	0.53
392_M	451_I	0.571	0.53
323_I	457_G	0.571	0.53
444_R	469_T	0.570	0.53
366_L	546_Y	0.570	0.53
143_Q	203_Q	0.569	0.52
171_Q	197_N	0.569	0.52
145_P	205_A	0.569	0.52
293_R	472_P	0.568	0.52
106_K	109_P	0.568	0.52
187_G	190_R	0.566	0.52
491_G	556_F	0.566	0.52
384_K	478_H	0.565	0.52
479_A	485_M	0.565	0.52
442_A	466_A	0.565	0.52
187_G	209_V	0.565	0.52
584_E	587_F	0.564	0.52
402_Y	484_S	0.564	0.52
373_T	467_A	0.563	0.52
400_K	416_T	0.562	0.52
257_D	444_R	0.562	0.52
121_E	125_E	0.562	0.52
435_M	460_G	0.562	0.52
406_D	419_Q	0.562	0.52
166_G	212_A	0.561	0.51
296_G	333_P	0.561	0.51
120_E	133_K	0.560	0.51
208_M	211_E	0.560	0.51
141_V	185_R	0.560	0.51
338_R	409_E	0.560	0.51
104_V	112_E	0.559	0.51
546_Y	573_L	0.559	0.51
395_I	401_I	0.559	0.51
195_P	400_K	0.558	0.51
107_P	113_A	0.558	0.51
303_V	309_I	0.557	0.51
474_M	502_D	0.557	0.51
387_T	592_L	0.557	0.51
580_E	583_D	0.557	0.51
410_V	468_Q	0.556	0.51
547_W	552_D	0.556	0.51
313_T	402_Y	0.555	0.51
467_A	481_D	0.554	0.51
290_G	297_E	0.554	0.51
549_P	563_F	0.554	0.51
309_I	432_D	0.553	0.50
171_Q	185_R	0.553	0.50
549_P	568_Q	0.553	0.50
177_G	180_S	0.553	0.50
118_R	138_F	0.552	0.50
297_E	400_K	0.551	0.50
389_N	415_D	0.550	0.50
445_S	500_F	0.549	0.50
374_V	474_M	0.548	0.50
111_A	129_I	0.546	0.50
178_D	200_N	0.545	0.49
296_G	312_S	0.544	0.49
393_S	396_P	0.543	0.49
263_P	282_F	0.542	0.49
236_L	434_D	0.541	0.49
357_S	572_L	0.541	0.49
261_I	445_S	0.540	0.49
310_V	333_P	0.540	0.49
299_M	452_V	0.540	0.49
120_E	130_S	0.539	0.49
157_A	172_M	0.539	0.49
576_A	579_R	0.538	0.49
261_I	416_T	0.538	0.49
467_A	585_M	0.538	0.49
377_V	485_M	0.537	0.48
366_L	391_I	0.537	0.48
192_A	199_I	0.537	0.48
387_T	450_I	0.536	0.48
301_D	351_T	0.536	0.48
342_D	411_I	0.536	0.48
249_V	280_V	0.536	0.48
432_D	576_A	0.536	0.48
402_Y	418_Q	0.536	0.48
221_R	224_V	0.535	0.48
448_D	501_M	0.533	0.48
108_A	114_E	0.532	0.48
374_V	508_L	0.532	0.48
155_F	549_P	0.532	0.48
376_V	540_V	0.531	0.48
547_W	551_E	0.530	0.48
433_V	437_D	0.530	0.48
124_E	129_I	0.529	0.47
550_V	576_A	0.529	0.47
172_M	205_A	0.529	0.47
282_F	300_G	0.528	0.47
99_I	129_I	0.528	0.47
384_K	453_G	0.528	0.47
381_A	409_E	0.528	0.47
485_M	558_G	0.528	0.47
249_V	270_H	0.527	0.47
286_D	507_A	0.526	0.47
250_M	314_L	0.526	0.47
362_A	544_A	0.526	0.47
283_G	584_E	0.526	0.47
393_S	449_Y	0.526	0.47
433_V	492_E	0.525	0.47
292_L	352_K	0.525	0.47
535_E	593_E	0.525	0.47
318_S	339_Q	0.525	0.47
345_L	412_P	0.525	0.47
325_S	334_S	0.524	0.47
363_Y	390_S	0.524	0.47
295_M	575_Y	0.524	0.47
239_D	584_E	0.524	0.47
481_D	502_D	0.523	0.47
162_D	166_G	0.523	0.47
154_N	175_D	0.522	0.47
159_T	523_V	0.521	0.46
173_S	176_S	0.521	0.46
416_T	448_D	0.521	0.46
209_V	212_A	0.520	0.46
380_T	488_R	0.520	0.46
369_E	404_A	0.519	0.46
482_I	485_M	0.519	0.46
554_I	558_G	0.519	0.46
444_R	453_G	0.519	0.46
380_T	444_R	0.518	0.46
341_D	389_N	0.517	0.46
530_E	534_K	0.517	0.46
234_Y	558_G	0.517	0.46
570_A	573_L	0.517	0.46
303_V	424_E	0.515	0.46
501_M	555_V	0.514	0.46
245_P	282_F	0.514	0.46
585_M	592_L	0.514	0.46
266_C	548_D	0.514	0.46
380_T	478_H	0.514	0.46
453_G	478_H	0.514	0.46
484_S	543_Q	0.513	0.45
338_R	454_E	0.513	0.45
191_V	268_V	0.513	0.45
245_P	302_P	0.513	0.45
308_P	440_A	0.512	0.45
199_I	217_F	0.512	0.45
360_L	494_I	0.512	0.45
484_S	562_S	0.511	0.45
161_A	191_V	0.511	0.45
311_D	443_L	0.511	0.45
469_T	488_R	0.511	0.45
328_V	480_S	0.511	0.45
122_L	127_V	0.510	0.45
321_N	342_D	0.510	0.45
351_T	364_L	0.510	0.45
293_R	468_Q	0.510	0.45
162_D	194_S	0.509	0.45
373_T	464_F	0.509	0.45
414_H	439_V	0.509	0.45
311_D	444_R	0.509	0.45
579_R	586_D	0.509	0.45
108_A	120_E	0.507	0.45
297_E	303_V	0.507	0.45
342_D	345_L	0.507	0.45
371_E	543_Q	0.507	0.45
178_D	183_Q	0.507	0.45
409_E	454_E	0.506	0.45
363_Y	540_V	0.506	0.45
568_Q	571_T	0.506	0.45
250_M	330_L	0.505	0.44
477_F	509_F	0.505	0.44
110_E	114_E	0.505	0.44
492_E	498_E	0.504	0.44
382_S	598_E	0.504	0.44
550_V	554_I	0.504	0.44
478_H	488_R	0.503	0.44
184_M	212_A	0.503	0.44
352_K	515_Q	0.503	0.44
108_A	118_R	0.503	0.44
444_R	454_E	0.503	0.44
465_Q	483_V	0.503	0.44
550_V	553_E	0.502	0.44
562_S	565_L	0.501	0.44
260_V	337_I	0.501	0.44
244_G	278_T	0.501	0.44
314_L	390_S	0.501	0.44
546_Y	575_Y	0.500	0.44
299_M	397_R	0.500	0.44

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
4phtA	1	0.6423	100	0.528	Contact Map
4ksrA	3	0.5469	100	0.584	Contact Map
1p9rA	1	0.5612	100	0.604	Contact Map
2oap1	3	0.7965	100	0.627	Contact Map
4ihqA	3	0.8013	100	0.65	Contact Map
2ewvA	3	0.5199	100	0.703	Contact Map
3jvvA	3	0.5103	100	0.713	Contact Map
4bloA	4	0.399	100	0.786	Contact Map
2eyuA	1	0.3657	100	0.786	Contact Map
2gzaA	3	0.469	100	0.806	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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