Q9HQX2 - HALSA - GREMLIN Contacts

Home
GREMLIN
- Submit - Monomer
- Submit - Complex
Contacts
Metagenomics
- Contacts
- Structures
Structures
- List
Old Projects
- Complexes (2014)
- PFAM (2013)

Q9HQX2 - Uncharacterized protein

UniProt:	Q9HQX2	Sequences: MSESEYKIADGSGKFLQAVKDGRRMKDAQWSKGRILLSNKRIVLAGSEGKRNLPLSEVQGLSGRHDVNQTVAKVGNYVSIRMTNESVMLVSLGDNTETFESKLYGALLDQTELQVKHPAVEGGVVTDEQFERARIKVDESELSVAMSNGSFVSVELDDVGSAEAASLEVNGDTKPVLKVEHTVNRDTSVQTYFATDSHTASILESLLTKEAEKSQGSVELSETEKRVLMALYSGVSSFEIPDFLGMDVDEVESIFERLIEVDVLEEVRKRREVTMKTRGRNIASEAINEE	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	290 (273)
Sequences:	117 (95)
Seq/√Len:	5.8

HALSA - Q9HQX2 Q9HQX1

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
275_M	279_G	3.173	0.80
43_V	127_D	2.856	0.72
58_V	196_D	2.789	0.71
187_T	191_T	2.725	0.69
130_F	234_G	2.681	0.67
142_L	193_F	2.570	0.64
193_F	265_E	2.496	0.61
133_A	167_L	2.445	0.60
171_G	250_E	2.415	0.59
130_F	270_R	2.390	0.58
38_S	156_L	2.367	0.57
231_L	236_S	2.334	0.56
182_T	191_T	2.324	0.56
103_L	107_L	2.289	0.54
30_W	124_V	2.239	0.53
191_T	283_A	2.215	0.52
122_G	232_Y	2.195	0.51
267_V	270_R	2.177	0.51
232_Y	275_M	2.174	0.50
60_G	205_S	2.110	0.48
42_I	232_Y	2.015	0.45
9_A	43_V	2.014	0.45
196_D	208_T	2.009	0.45
177_L	204_E	2.003	0.45
234_G	270_R	2.002	0.45
40_K	111_T	1.991	0.44
253_S	257_R	1.969	0.43
104_Y	263_V	1.903	0.41
9_A	137_V	1.856	0.40
42_I	80_I	1.811	0.38
91_S	262_D	1.787	0.37
24_R	172_D	1.776	0.37
219_E	262_D	1.772	0.37
113_L	135_I	1.755	0.36
115_V	171_G	1.755	0.36
113_L	224_E	1.734	0.36
10_D	34_R	1.730	0.35
30_W	270_R	1.705	0.35
73_K	156_L	1.697	0.34
48_E	142_L	1.679	0.34
169_V	245_G	1.664	0.33
245_G	262_D	1.648	0.33
60_G	276_K	1.631	0.32
30_W	130_F	1.612	0.32
82_M	127_D	1.610	0.32
80_I	154_V	1.607	0.32
46_G	188_S	1.593	0.31
108_L	125_V	1.578	0.31
169_V	193_F	1.572	0.31
257_R	265_E	1.568	0.30
122_G	279_G	1.566	0.30
176_V	233_S	1.551	0.30
80_I	254_I	1.551	0.30
99_F	125_V	1.533	0.29
90_V	96_T	1.529	0.29
15_F	33_G	1.522	0.29
234_G	245_G	1.517	0.29
207_L	233_S	1.501	0.29
173_T	198_H	1.464	0.28
230_A	280_R	1.458	0.27
33_G	156_L	1.451	0.27
264_L	276_K	1.433	0.27
38_S	139_E	1.431	0.27
41_R	284_S	1.427	0.26
206_L	263_V	1.422	0.26
35_I	39_N	1.421	0.26
123_G	279_G	1.417	0.26
230_A	234_G	1.415	0.26
121_E	187_T	1.396	0.26
128_E	227_V	1.388	0.25
76_N	161_S	1.384	0.25
99_F	224_E	1.381	0.25
88_M	146_M	1.379	0.25
193_F	273_V	1.377	0.25
87_V	260_E	1.372	0.25
27_D	51_R	1.369	0.25
91_S	232_Y	1.368	0.25
30_W	234_G	1.361	0.25
8_I	14_K	1.360	0.25
10_D	45_A	1.359	0.25
35_I	73_K	1.356	0.25
58_V	144_V	1.344	0.24
38_S	226_R	1.336	0.24
84_N	247_D	1.335	0.24
202_I	274_T	1.334	0.24
84_N	207_L	1.333	0.24
125_V	189_V	1.326	0.24
229_M	267_V	1.321	0.24
30_W	267_V	1.314	0.24
5_E	34_R	1.313	0.24
43_V	58_V	1.307	0.23
97_E	162_A	1.297	0.23
232_Y	279_G	1.297	0.23
8_I	142_L	1.296	0.23
123_G	275_M	1.293	0.23
25_M	137_V	1.289	0.23
53_L	177_L	1.283	0.23
35_I	152_V	1.270	0.22
199_T	208_T	1.262	0.22
226_R	233_S	1.257	0.22
109_D	172_D	1.249	0.22
125_V	138_D	1.248	0.22
144_V	191_T	1.244	0.22
8_I	194_A	1.241	0.22
58_V	176_V	1.241	0.22
122_G	275_M	1.236	0.22
38_S	105_G	1.234	0.22
137_V	163_E	1.216	0.21
172_D	194_A	1.215	0.21
142_L	189_V	1.212	0.21
50_K	99_F	1.211	0.21
123_G	232_Y	1.210	0.21
84_N	233_S	1.207	0.21
173_T	193_F	1.193	0.21
170_N	174_K	1.180	0.20
136_K	145_A	1.180	0.20
30_W	229_M	1.178	0.20
43_V	181_H	1.174	0.20
90_V	159_V	1.172	0.20
84_N	186_D	1.171	0.20
188_S	287_I	1.170	0.20
60_G	206_L	1.163	0.20
42_I	184_N	1.163	0.20
5_E	10_D	1.137	0.19
193_F	262_D	1.137	0.19
162_A	249_D	1.127	0.19
114_Q	246_M	1.124	0.19
219_E	261_V	1.119	0.19
103_L	154_V	1.102	0.19
93_G	97_E	1.102	0.19
147_S	171_G	1.099	0.19
8_I	188_S	1.092	0.18
89_L	136_K	1.074	0.18
180_E	243_F	1.066	0.18
114_Q	132_R	1.057	0.18
33_G	52_N	1.056	0.18
42_I	121_E	1.056	0.18
51_R	169_V	1.052	0.18
159_V	210_E	1.037	0.17
175_P	232_Y	1.034	0.17
32_K	227_V	1.033	0.17
37_L	108_L	1.027	0.17
138_D	242_D	1.021	0.17
99_F	228_L	1.019	0.17
203_L	239_E	1.015	0.17
270_R	273_V	1.012	0.17
33_G	88_M	1.005	0.17
252_E	256_E	1.002	0.17
58_V	88_M	0.998	0.17
8_I	245_G	0.991	0.16
114_Q	203_L	0.989	0.16
128_E	186_D	0.989	0.16
218_V	251_V	0.988	0.16
58_V	193_F	0.988	0.16
28_A	115_V	0.987	0.16
41_R	181_H	0.979	0.16
142_L	226_R	0.977	0.16
168_E	177_L	0.976	0.16
196_D	199_T	0.975	0.16
218_V	247_D	0.971	0.16
119_A	122_G	0.970	0.16
43_V	140_S	0.970	0.16
42_I	187_T	0.970	0.16
190_Q	287_I	0.970	0.16
47_S	127_D	0.969	0.16
41_R	54_P	0.968	0.16
276_K	288_N	0.965	0.16
198_H	258_L	0.964	0.16
137_V	219_E	0.963	0.16
195_T	236_S	0.962	0.16
104_Y	135_I	0.960	0.16
234_G	237_S	0.960	0.16
34_R	118_P	0.955	0.16
261_V	287_I	0.951	0.16
63_G	121_E	0.951	0.16
198_H	232_Y	0.949	0.16
6_Y	266_E	0.939	0.15
87_V	191_T	0.936	0.15
104_Y	206_L	0.932	0.15
75_G	163_E	0.931	0.15
8_I	61_L	0.930	0.15
53_L	167_L	0.925	0.15
64_R	125_V	0.921	0.15
42_I	129_Q	0.920	0.15
162_A	215_Q	0.918	0.15
70_T	156_L	0.912	0.15
60_G	191_T	0.901	0.15
87_V	187_T	0.895	0.15
216_G	264_L	0.888	0.15
237_S	273_V	0.883	0.14
257_R	264_L	0.883	0.14
142_L	221_S	0.880	0.14
36_L	101_S	0.871	0.14
133_A	243_F	0.869	0.14
138_D	171_G	0.869	0.14
6_Y	156_L	0.863	0.14
207_L	227_V	0.863	0.14
199_T	240_I	0.858	0.14
174_K	224_E	0.854	0.14
239_E	264_L	0.849	0.14
78_V	263_V	0.848	0.14
168_E	257_R	0.848	0.14
34_R	45_A	0.847	0.14
44_L	181_H	0.844	0.14
6_Y	173_T	0.842	0.14
9_A	85_E	0.841	0.14
8_I	200_A	0.838	0.14
216_G	254_I	0.837	0.14
226_R	255_F	0.837	0.14
194_A	222_E	0.823	0.13
33_G	226_R	0.822	0.13
70_T	159_V	0.822	0.13
59_Q	221_S	0.817	0.13
166_S	171_G	0.815	0.13
231_L	248_V	0.815	0.13
61_L	162_A	0.806	0.13
233_S	279_G	0.805	0.13
220_L	244_L	0.804	0.13
70_T	142_L	0.798	0.13
48_E	76_N	0.798	0.13
90_V	133_A	0.798	0.13
252_E	273_V	0.796	0.13
140_S	180_E	0.795	0.13
84_N	229_M	0.795	0.13
108_L	189_V	0.791	0.13
165_A	274_T	0.791	0.13
6_Y	154_V	0.788	0.13
108_L	247_D	0.788	0.13
37_L	241_P	0.780	0.13
116_K	284_S	0.779	0.13
180_E	206_L	0.776	0.13
82_M	218_V	0.775	0.13
220_L	234_G	0.774	0.13
238_F	251_V	0.774	0.13
167_L	233_S	0.773	0.13
144_V	190_Q	0.772	0.13
54_P	265_E	0.771	0.13
109_D	282_I	0.769	0.13
267_V	286_A	0.769	0.13
33_G	38_S	0.769	0.13
236_S	280_R	0.764	0.13
152_V	233_S	0.762	0.13
36_L	44_L	0.761	0.12
5_E	15_F	0.757	0.12
98_T	162_A	0.754	0.12
115_V	223_T	0.754	0.12
38_S	160_G	0.750	0.12
168_E	174_K	0.749	0.12
37_L	230_A	0.748	0.12
10_D	50_K	0.748	0.12
146_M	173_T	0.747	0.12
28_A	218_V	0.745	0.12
40_K	262_D	0.745	0.12
161_S	277_T	0.742	0.12
235_V	283_A	0.741	0.12
11_G	255_F	0.739	0.12
109_D	287_I	0.735	0.12
158_D	263_V	0.731	0.12
109_D	182_T	0.730	0.12
89_L	116_K	0.728	0.12
103_L	264_L	0.723	0.12
33_G	44_L	0.722	0.12
140_S	264_L	0.721	0.12
31_S	51_R	0.720	0.12
182_T	251_V	0.719	0.12
156_L	160_G	0.718	0.12
64_R	74_V	0.718	0.12
254_I	273_V	0.717	0.12
84_N	273_V	0.715	0.12
133_A	184_N	0.710	0.12
27_D	84_N	0.710	0.12
28_A	242_D	0.707	0.12
34_R	117_H	0.704	0.12
231_L	243_F	0.697	0.12
167_L	200_A	0.696	0.12
61_L	256_E	0.696	0.12
110_Q	205_S	0.689	0.11
6_Y	255_F	0.687	0.11
160_G	180_E	0.686	0.11
56_S	107_L	0.682	0.11
11_G	199_T	0.681	0.11
220_L	270_R	0.678	0.11
33_G	271_R	0.660	0.11
135_I	228_L	0.660	0.11
37_L	117_H	0.657	0.11
120_V	130_F	0.656	0.11
17_Q	180_E	0.654	0.11
165_A	276_K	0.653	0.11
103_L	135_I	0.653	0.11
205_S	226_R	0.649	0.11
29_Q	80_I	0.649	0.11
33_G	138_D	0.647	0.11
8_I	62_S	0.644	0.11
99_F	230_A	0.643	0.11
167_L	232_Y	0.638	0.11
229_M	236_S	0.638	0.11
248_V	252_E	0.632	0.11
147_S	256_E	0.630	0.11
197_S	216_G	0.628	0.11
142_L	194_A	0.628	0.11
246_M	267_V	0.626	0.11
163_E	186_D	0.626	0.11
70_T	248_V	0.625	0.11
150_S	226_R	0.623	0.11
124_V	255_F	0.618	0.10
57_E	106_A	0.618	0.10
131_E	232_Y	0.617	0.10
171_G	277_T	0.617	0.10
30_W	243_F	0.616	0.10
151_F	191_T	0.615	0.10
9_A	255_F	0.615	0.10
158_D	181_H	0.614	0.10
222_E	232_Y	0.611	0.10
58_V	96_T	0.605	0.10
56_S	228_L	0.603	0.10
140_S	247_D	0.603	0.10
227_V	234_G	0.602	0.10
109_D	204_E	0.601	0.10
31_S	92_L	0.601	0.10
179_V	255_F	0.601	0.10
162_A	196_D	0.600	0.10
239_E	252_E	0.597	0.10
36_L	175_P	0.597	0.10
179_V	193_F	0.597	0.10
168_E	247_D	0.597	0.10
80_I	219_E	0.595	0.10
76_N	247_D	0.593	0.10
137_V	225_K	0.592	0.10
235_V	238_F	0.592	0.10
59_Q	219_E	0.591	0.10
35_I	76_N	0.591	0.10
78_V	118_P	0.591	0.10
127_D	170_N	0.588	0.10
202_I	248_V	0.588	0.10
202_I	261_V	0.587	0.10
212_E	274_T	0.587	0.10
172_D	254_I	0.586	0.10
45_A	228_L	0.586	0.10
121_E	283_A	0.585	0.10
94_D	141_E	0.585	0.10
135_I	165_A	0.584	0.10
230_A	245_G	0.584	0.10
49_G	277_T	0.581	0.10
266_E	281_N	0.574	0.10
5_E	33_G	0.572	0.10
35_I	91_S	0.570	0.10
92_L	96_T	0.569	0.10
108_L	241_P	0.568	0.10
232_Y	288_N	0.567	0.10
180_E	230_A	0.567	0.10
29_Q	243_F	0.567	0.10
23_R	75_G	0.566	0.10
64_R	152_V	0.566	0.10
75_G	219_E	0.562	0.10
41_R	152_V	0.561	0.10
42_I	221_S	0.560	0.10
5_E	40_K	0.558	0.10
219_E	225_K	0.557	0.10
55_L	103_L	0.556	0.10
251_V	280_R	0.553	0.10
132_R	180_E	0.552	0.10
80_I	93_G	0.549	0.10
135_I	154_V	0.546	0.10
36_L	39_N	0.544	0.10
160_G	202_I	0.544	0.10
150_S	222_E	0.543	0.10
121_E	150_S	0.542	0.10
10_D	41_R	0.542	0.10
245_G	251_V	0.541	0.10
200_A	226_R	0.540	0.10
77_Y	155_E	0.540	0.10
10_D	43_V	0.538	0.09
57_E	207_L	0.538	0.09
170_N	197_S	0.537	0.09
276_K	279_G	0.534	0.09
172_D	249_D	0.531	0.09
8_I	288_N	0.529	0.09
112_E	147_S	0.529	0.09
208_T	211_A	0.528	0.09
194_A	244_L	0.528	0.09
121_E	227_V	0.526	0.09
89_L	188_S	0.524	0.09
117_H	194_A	0.523	0.09
162_A	165_A	0.521	0.09
228_L	275_M	0.519	0.09
91_S	156_L	0.518	0.09
177_L	201_S	0.518	0.09
167_L	226_R	0.516	0.09
120_V	194_A	0.515	0.09
149_G	192_Y	0.515	0.09
8_I	201_S	0.514	0.09
232_Y	264_L	0.514	0.09
189_V	244_L	0.513	0.09
166_S	219_E	0.513	0.09
218_V	263_V	0.512	0.09
116_K	282_I	0.511	0.09
58_V	166_S	0.511	0.09
31_S	254_I	0.509	0.09
76_N	88_M	0.509	0.09
106_A	175_P	0.509	0.09
70_T	250_E	0.508	0.09
104_Y	140_S	0.507	0.09
63_G	205_S	0.504	0.09
92_L	206_L	0.503	0.09
28_A	225_K	0.503	0.09
13_G	244_L	0.502	0.09
252_E	270_R	0.502	0.09
154_V	203_L	0.502	0.09
140_S	144_V	0.502	0.09
130_F	237_S	0.500	0.09

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
1p4xA	1	0.3483	97.9	0.911	Contact Map
2frhA	2	0.3621	97.8	0.912	Contact Map
3fm5A	4	0.3621	97.8	0.912	Contact Map
3bpvA	2	0.3345	97.8	0.913	Contact Map
4mnuA	2	0.3414	97.8	0.913	Contact Map
2fbhA	2	0.331	97.8	0.913	Contact Map
3u2rA	4	0.3448	97.7	0.913	Contact Map
1lj9A	2	0.3345	97.7	0.914	Contact Map
1jgsA	2	0.3517	97.7	0.914	Contact Map
2a61A	2	0.3379	97.7	0.914	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.0094 seconds.