GREMLIN Database
Q9HQX0 - Chemotaxis protein
UniProt: Q9HQX0 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 234 (218)
Sequences: 4648 (3633)
Seq/√Len: 246.1

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
71_D103_A3.0991.00
169_D197_R2.8161.00
121_S124_L2.7771.00
219_E229_S2.6401.00
8_E11_G2.5911.00
12_Y23_E2.5191.00
171_V192_V2.5171.00
65_W97_T2.4461.00
135_D145_N2.4151.00
44_V203_V2.3171.00
137_E143_V2.3041.00
196_L200_G2.2011.00
73_R116_R2.1941.00
111_R143_V2.1831.00
193_S218_F2.1411.00
111_R141_A2.1021.00
97_T157_H2.0541.00
15_L19_D2.0341.00
6_V15_L2.0321.00
146_D150_D2.0201.00
75_P96_A2.0121.00
46_T50_D2.0031.00
84_D124_L1.9991.00
93_S153_T1.9721.00
48_L170_L1.9451.00
101_E156_R1.9301.00
64_I78_L1.8981.00
34_N103_A1.8771.00
83_L147_R1.8511.00
96_A152_V1.8451.00
122_D131_Q1.8331.00
83_L148_V1.7971.00
36_T71_D1.7821.00
77_S81_L1.7741.00
84_D132_E1.7491.00
83_L151_L1.7441.00
7_E11_G1.7171.00
78_L172_A1.7141.00
34_N70_A1.6691.00
104_L156_R1.6571.00
92_V151_L1.6521.00
42_E46_T1.6451.00
159_L176_V1.6351.00
146_D149_K1.6181.00
138_G141_A1.5401.00
124_L133_Y1.5351.00
187_P191_T1.5341.00
95_L155_E1.5101.00
82_A92_V1.5031.00
173_C192_V1.4941.00
177_C189_L1.4291.00
49_R84_D1.4251.00
105_A109_A1.4191.00
95_L168_F1.4101.00
171_V196_L1.4021.00
46_T49_R1.3971.00
75_P94_I1.3931.00
177_C188_I1.3771.00
34_N100_D1.3761.00
80_M84_D1.3731.00
15_L23_E1.3691.00
79_A151_L1.3621.00
190_D217_R1.3561.00
117_T130_P1.3511.00
201_H221_E1.3411.00
160_I184_Y1.3411.00
79_A94_I1.3381.00
16_L27_L1.3231.00
134_V144_V1.3101.00
80_M133_Y1.2941.00
64_I82_A1.2891.00
110_G144_V1.2821.00
67_A159_L1.2761.00
83_L133_Y1.2731.00
75_P152_V1.2601.00
29_D100_D1.2601.00
29_D102_D1.2581.00
105_A108_R1.2501.00
186_L190_D1.2491.00
68_A176_V1.2381.00
66_S172_A1.2361.00
39_F77_S1.2311.00
182_K185_K1.2291.00
37_E119_D1.2111.00
114_S136_R1.2071.00
66_S78_L1.2051.00
41_D44_V1.1981.00
148_V151_L1.1941.00
51_V54_E1.1931.00
63_D93_S1.1821.00
60_R90_R1.1611.00
167_G197_R1.1571.00
181_D184_Y1.1571.00
101_E105_A1.1551.00
164_P188_I1.1421.00
11_G14_T1.1281.00
69_C75_P1.1261.00
114_S142_F1.1251.00
70_A103_A1.1221.00
144_V148_V1.1201.00
113_E116_R1.1191.00
14_T18_E1.1191.00
32_S99_I1.1171.00
49_R85_A1.1081.00
13_L17_E1.1081.00
221_E229_S1.1041.00
177_C204_L1.1021.00
76_Y149_K1.0971.00
39_F124_L1.0951.00
122_D130_P1.0861.00
83_L92_V1.0761.00
52_L201_H1.0751.00
97_T155_E1.0531.00
66_S69_C1.0471.00
176_V180_I1.0401.00
56_A62_I1.0351.00
135_D143_V1.0341.00
47_A203_V1.0231.00
143_V149_K1.0141.00
80_M124_L1.0131.00
137_E141_A1.0121.00
115_T118_A1.0051.00
43_K46_T1.0021.00
61_S91_N0.9911.00
59_V169_D0.9891.00
48_L78_L0.9811.00
25_A101_E0.9671.00
106_R109_A0.9661.00
190_D194_K0.9611.00
47_A51_V0.9601.00
12_Y27_L0.9601.00
214_V217_R0.9531.00
172_A203_V0.9491.00
80_M134_V0.9461.00
29_D101_E0.9411.00
111_R137_E0.9391.00
32_S100_D0.9351.00
148_V152_V0.9341.00
12_Y15_L0.9331.00
76_Y154_F0.9321.00
84_D133_Y0.9251.00
47_A227_I0.9251.00
67_A176_V0.9241.00
55_L201_H0.9221.00
49_R81_L0.9221.00
4_R15_L0.9191.00
147_R150_D0.9151.00
158_D161_T0.9021.00
41_D206_Q0.8971.00
123_Q132_E0.8971.00
53_L82_A0.8861.00
143_V146_D0.8851.00
61_S93_S0.8851.00
100_D103_A0.8760.99
68_A192_V0.8720.99
117_T120_I0.8570.99
22_D26_E0.8560.99
51_V55_L0.8510.99
192_V218_F0.8500.99
23_E26_E0.8450.99
9_Y13_L0.8440.99
4_R23_E0.8420.99
199_G229_S0.8380.99
220_A223_P0.8310.99
79_A148_V0.8240.99
51_V222_D0.8210.99
187_P190_D0.8150.99
53_L85_A0.8130.99
114_S130_P0.8030.99
4_R26_E0.8030.99
117_T142_F0.8010.99
44_V206_Q0.7960.99
136_R142_F0.7950.99
168_F171_V0.7890.99
103_A107_A0.7870.99
201_H227_I0.7830.99
61_S90_R0.7780.99
39_F120_I0.7740.99
19_D22_D0.7710.99
95_L165_K0.7650.99
180_I184_Y0.7610.99
124_L130_P0.7610.99
196_L218_F0.7570.99
52_L56_A0.7540.98
157_H163_D0.7540.98
204_L210_L0.7520.98
3_R26_E0.7480.98
130_P134_V0.7460.98
107_A154_F0.7330.98
45_W77_S0.7200.98
184_Y188_I0.7180.98
32_S103_A0.7100.98
27_L100_D0.7100.98
123_Q131_Q0.7010.98
15_L18_E0.7000.98
191_T194_K0.7000.98
71_D106_R0.6980.98
106_R116_R0.6970.97
10_A13_L0.6970.97
134_V142_F0.6970.97
165_K168_F0.6960.97
59_V197_R0.6950.97
193_S217_R0.6920.97
136_R141_A0.6850.97
183_Q186_L0.6810.97
63_D168_F0.6780.97
63_D165_K0.6760.97
81_L85_A0.6740.97
102_D105_A0.6720.97
102_D106_R0.6700.97
113_E141_A0.6680.97
114_S117_T0.6650.97
114_S118_A0.6610.97
62_I90_R0.6610.97
25_A29_D0.6600.97
26_E29_D0.6600.97
190_D214_V0.6540.96
52_L170_L0.6530.96
109_A143_V0.6530.96
112_Y144_V0.6510.96
167_G195_S0.6490.96
66_S75_P0.6480.96
67_A192_V0.6470.96
113_E117_T0.6450.96
54_E201_H0.6450.96
60_R197_R0.6450.96
64_I170_L0.6450.96
175_N179_Y0.6430.96
185_K189_L0.6430.96
48_L81_L0.6430.96
68_A173_C0.6390.96
203_V227_I0.6380.96
189_L214_V0.6370.96
193_S230_R0.6350.96
106_R112_Y0.6310.96
186_L216_E0.6300.95
120_I134_V0.6290.95
36_T70_A0.6260.95
35_V185_K0.6260.95
124_L132_E0.6250.95
52_L203_V0.6250.95
136_R139_D0.6240.95
48_L172_A0.6240.95
84_D123_Q0.6230.95
40_R179_Y0.6220.95
101_E108_R0.6210.95
60_R89_P0.6180.95
76_Y152_V0.6140.95
157_H161_T0.6110.95
120_I124_L0.6090.95
130_P133_Y0.6070.94
178_I205_G0.6060.94
12_Y16_L0.6050.94
178_I207_T0.6050.94
45_W48_L0.6040.94
156_R161_T0.5950.94
30_T33_V0.5940.94
52_L82_A0.5890.94
7_E10_A0.5870.93
37_E185_K0.5850.93
10_A14_T0.5840.93
62_I82_A0.5840.93
67_A172_A0.5800.93
68_A97_T0.5790.93
55_L229_S0.5770.93
35_V100_D0.5760.93
33_V100_D0.5760.93
65_W68_A0.5720.93
87_L90_R0.5720.93
201_H229_S0.5710.92
165_K195_S0.5690.92
94_I151_L0.5690.92
182_K186_L0.5660.92
185_K226_R0.5650.92
164_P191_T0.5630.92
103_A106_R0.5620.92
38_F112_Y0.5610.92
48_L53_L0.5610.92
22_D25_A0.5600.92
49_R124_L0.5580.92
21_D25_A0.5570.92
21_D24_R0.5560.91
29_D34_N0.5530.91
4_R12_Y0.5530.91
14_T17_E0.5520.91
157_H195_S0.5500.91
68_A188_I0.5470.91
106_R113_E0.5470.91
23_E27_L0.5460.91
33_V179_Y0.5460.91
53_L201_H0.5440.91
96_A107_A0.5440.91
40_R175_N0.5430.91
160_I188_I0.5430.91
189_L210_L0.5420.90
82_A94_I0.5410.90
39_F81_L0.5380.90
53_L56_A0.5340.90
80_M148_V0.5320.90
220_A228_Y0.5310.90
80_M144_V0.5310.90
115_T185_K0.5270.89
47_A222_D0.5260.89
171_V195_S0.5240.89
64_I94_I0.5240.89
43_K206_Q0.5230.89
108_R155_E0.5220.89
26_E30_T0.5200.89
35_V226_R0.5200.89
69_C107_A0.5200.89
50_D85_A0.5190.88
33_V68_A0.5190.88
184_Y187_P0.5180.88
188_I191_T0.5160.88
44_V185_K0.5160.88
6_V12_Y0.5150.88
59_V90_R0.5140.88
31_L158_D0.5130.88
58_T199_G0.5120.88
70_A178_I0.5070.87
158_D181_D0.5050.87
34_N185_K0.5050.87
54_E85_A0.5050.87
135_D138_G0.5020.87
64_I172_A0.5020.87
6_V11_G0.5010.87
80_M83_L0.5000.87
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
1af7A 1 0.9402 100 0.316 Contact Map
3i53A 2 0.8077 99.7 0.753 Contact Map
4qnuA 2 0.8077 99.7 0.755 Contact Map
3gwzA 3 0.8162 99.7 0.758 Contact Map
4z2yA 2 0.7436 99.7 0.766 Contact Map
2ip2A 2 0.812 99.6 0.778 Contact Map
4gqbA 4 0.8376 99.6 0.778 Contact Map
1qzzA 2 0.7949 99.6 0.782 Contact Map
1o9gA 1 0.9145 99.5 0.786 Contact Map
2r3sA 4 0.8248 99.5 0.787 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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