Q9HQW7 - HALSA - GREMLIN Contacts

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Q9HQW7 - Chemotaxis protein

UniProt:	Q9HQW7	Sequences: MDDYLEAFVREGEEHVTSLNNALLELESDPGNEEAMDEIFRTAHTLKGNFGAMGFEDASDLAHAVEDLLDEMRQGNLEVTSDRMDRIFEGIDGIEACLDEIQATGDVDRDVTGTIESVRAVLDEVDGDGGSGTTTSSGDAGSPAGDGDVDATRVVDADTIDAAEDPVYHIHIDMGDSQMKGVDGMFVLEEATEAFDLLGAEPSPDAINDGEYGDGFELVVATPSDEVSDTVAAFPKLSDATVTAVGDDEHAPDADSGTEADASADDDADDAGTTADSGSSSGGSSAIDNTDTEIQSVRVDVDQLDELHGLVEQLVTTRIKLRRGMEESDREVLDELDELDKITSSLQDTVMDMRLVPMKKIVGKFPRLVRDLAREQDKDIDFVVEGDDVELDRTILTEISDPLMHLLRNAVDHGIEKPAVREDNGKDREGTITLSAERDRDHVLIQVRDDGAGIDHDTMREKAIEKGVKTREEVQDMPDDDVEDLVFHPGFSTNDEVTDVSGRGVGMDVVRDTVTRLDGSVSVDSTPGEGTTFTMTLPVTVAIVKVLFVESGGEEYGIPIKTVDEISRMKSVKSVDGEEVITYDETVYPLVRLGDALNVPDETRNGDGMLVRIRDSERQVAVHCDDVRGQEEVVVKPFEGILSGIPGLSGAAVLGEGDVVTILDVATL	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	668 (639)
Sequences:	2419 (1836)
Seq/√Len:	72.6

ECOLI - CHEA
BACSU - CHEA
HALSA - Q9HQW7

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
454_I	459_M	7.939	1.00
422_E	428_R	7.880	1.00
526_T	529_E	7.822	1.00
379_D	428_R	7.573	1.00
420_V	452_A	6.750	1.00
424_N	528_G	6.695	1.00
381_D	429_E	6.099	1.00
29_D	32_N	4.970	1.00
89_E	117_S	4.786	1.00
448_R	532_T	4.341	1.00
460_R	469_K	4.276	1.00
456_H	479_D	4.211	1.00
379_D	429_E	4.211	1.00
385_E	433_T	4.147	1.00
579_E	592_R	4.064	1.00
455_D	527_P	4.037	1.00
383_V	431_T	3.955	1.00
372_L	500_V	3.872	1.00
417_K	420_V	3.841	1.00
462_K	465_E	3.674	1.00
456_H	482_V	3.605	1.00
565_E	584_D	3.427	1.00
550_E	626_D	3.301	1.00
420_V	423_D	3.300	1.00
460_R	482_V	3.280	1.00
411_V	432_I	3.204	1.00
191_A	195_F	3.201	1.00
461_E	465_E	3.197	1.00
36_M	72_M	3.176	1.00
458_T	495_D	3.129	1.00
187_V	195_F	3.041	1.00
590_L	610_L	2.928	1.00
454_I	483_E	2.887	1.00
586_T	619_Q	2.828	1.00
478_P	481_D	2.791	1.00
380_I	411_V	2.749	1.00
487_F	521_V	2.705	1.00
420_V	424_N	2.693	1.00
546_V	557_G	2.561	1.00
456_H	460_R	2.488	1.00
457_D	461_E	2.457	1.00
479_D	482_V	2.444	1.00
71_E	76_N	2.406	1.00
64_A	119_R	2.405	1.00
460_R	464_I	2.380	1.00
456_H	527_P	2.338	1.00
381_D	431_T	2.331	1.00
380_I	415_I	2.261	1.00
68_L	118_V	2.207	1.00
179_M	183_D	2.195	1.00
483_E	525_S	2.181	1.00
375_E	499_D	2.172	1.00
471_R	475_Q	2.140	1.00
486_V	507_M	2.132	1.00
468_V	488_H	2.127	1.00
468_V	485_L	2.085	1.00
433_T	448_R	2.031	1.00
65_V	90_G	2.025	1.00
456_H	483_E	2.005	1.00
437_E	446_Q	2.005	1.00
181_G	184_G	1.999	1.00
597_L	663_L	1.993	1.00
487_F	523_V	1.981	1.00
183_D	187_V	1.964	1.00
610_L	621_A	1.946	1.00
582_T	585_E	1.893	1.00
27_E	370_R	1.884	1.00
480_D	524_D	1.866	1.00
415_I	430_G	1.863	1.00
15_H	42_T	1.861	1.00
469_K	477_M	1.851	1.00
477_M	485_L	1.848	1.00
33_E	75_G	1.848	1.00
452_A	458_T	1.833	1.00
556_Y	599_V	1.824	1.00
407_L	432_I	1.806	1.00
180_K	183_D	1.790	1.00
369_V	411_V	1.779	1.00
187_V	191_A	1.774	1.00
362_V	434_L	1.760	1.00
231_V	234_F	1.758	1.00
13_E	102_Q	1.758	1.00
43_A	62_A	1.748	1.00
170_I	242_V	1.746	1.00
410_A	533_F	1.738	1.00
452_A	455_D	1.734	1.00
40_F	73_R	1.734	1.00
173_D	215_G	1.705	1.00
297_V	304_L	1.705	1.00
465_E	495_D	1.680	1.00
581_I	610_L	1.673	1.00
418_P	428_R	1.667	1.00
116_E	120_A	1.665	1.00
80_T	83_R	1.653	1.00
179_M	184_G	1.636	1.00
592_R	623_H	1.617	0.99
588_Y	612_R	1.614	0.99
454_I	486_V	1.609	0.99
583_Y	612_R	1.608	0.99
442_H	536_T	1.603	0.99
417_K	452_A	1.592	0.99
207_I	212_Y	1.567	0.99
183_D	191_A	1.561	0.99
415_I	452_A	1.548	0.99
207_I	213_G	1.545	0.99
385_E	435_S	1.518	0.99
118_V	125_V	1.513	0.99
254_A	260_A	1.501	0.99
225_D	228_S	1.501	0.99
71_E	77_L	1.499	0.99
72_M	83_R	1.496	0.99
65_V	94_I	1.496	0.99
608_G	623_H	1.496	0.99
157_A	160_I	1.492	0.99
462_K	466_K	1.481	0.99
579_E	595_D	1.480	0.99
435_S	446_Q	1.475	0.99
524_D	534_T	1.467	0.99
480_D	522_S	1.465	0.99
57_D	107_V	1.461	0.99
359_K	387_D	1.454	0.99
361_I	366_P	1.449	0.99
51_G	59_S	1.430	0.99
364_K	400_S	1.426	0.99
229_D	233_A	1.422	0.99
548_F	654_L	1.421	0.99
518_D	635_V	1.417	0.99
33_E	37_D	1.415	0.99
171_H	217_E	1.411	0.99
85_D	374_R	1.404	0.98
483_E	527_P	1.400	0.98
507_M	533_F	1.373	0.98
228_S	235_P	1.372	0.98
318_R	557_G	1.370	0.98
523_V	533_F	1.370	0.98
594_G	601_D	1.362	0.98
168_Y	222_T	1.359	0.98
401_D	509_V	1.356	0.98
155_V	159_T	1.347	0.98
72_M	79_V	1.344	0.98
457_D	460_R	1.341	0.98
226_E	229_D	1.337	0.98
208_N	211_E	1.332	0.98
550_E	553_G	1.328	0.98
8_F	50_F	1.327	0.98
231_V	240_A	1.326	0.98
424_N	452_A	1.318	0.98
13_E	99_D	1.317	0.98
469_K	482_V	1.314	0.98
351_M	542_A	1.312	0.98
112_T	116_E	1.311	0.98
231_V	237_L	1.306	0.98
70_D	74_Q	1.304	0.97
133_T	137_S	1.298	0.97
356_V	396_L	1.297	0.97
558_I	611_V	1.295	0.97
17_T	95_E	1.295	0.97
494_N	497_V	1.293	0.97
27_E	30_P	1.287	0.97
469_K	485_L	1.286	0.97
545_K	632_E	1.282	0.97
271_A	275_A	1.280	0.97
132_G	135_T	1.276	0.97
435_S	448_R	1.273	0.97
459_M	482_V	1.273	0.97
464_I	477_M	1.268	0.97
184_G	187_V	1.267	0.97
174_M	187_V	1.264	0.97
180_K	184_G	1.264	0.97
20_N	88_F	1.258	0.97
83_R	121_V	1.252	0.97
261_D	264_A	1.248	0.97
557_G	632_E	1.247	0.97
486_V	523_V	1.235	0.97
419_A	422_E	1.232	0.96
613_I	665_V	1.231	0.96
216_F	220_V	1.231	0.96
446_Q	534_T	1.230	0.96
65_V	87_I	1.228	0.96
462_K	495_D	1.226	0.96
320_K	335_E	1.225	0.96
517_L	537_L	1.224	0.96
419_A	428_R	1.222	0.96
204_P	207_I	1.220	0.96
458_T	461_E	1.212	0.96
566_I	627_V	1.211	0.96
546_V	633_V	1.210	0.96
379_D	422_E	1.206	0.96
203_S	206_A	1.201	0.96
230_T	233_A	1.197	0.96
116_E	119_R	1.197	0.96
170_I	195_F	1.194	0.96
31_G	78_E	1.192	0.96
464_I	469_K	1.189	0.96
256_S	260_A	1.187	0.96
369_V	407_L	1.187	0.96
464_I	471_R	1.184	0.96
179_M	182_V	1.182	0.96
395_I	399_I	1.182	0.96
220_V	227_V	1.181	0.95
382_F	407_L	1.176	0.95
376_Q	411_V	1.163	0.95
183_D	195_F	1.160	0.95
350_V	353_M	1.160	0.95
265_D	268_A	1.157	0.95
168_Y	195_F	1.155	0.95
456_H	525_S	1.154	0.95
111_V	114_T	1.153	0.95
448_R	529_E	1.152	0.95
172_I	181_G	1.150	0.95
209_D	216_F	1.149	0.95
365_F	434_L	1.147	0.95
179_M	185_M	1.147	0.95
227_V	232_A	1.147	0.95
557_G	633_V	1.146	0.95
208_N	212_Y	1.146	0.95
483_E	523_V	1.142	0.95
185_M	188_L	1.142	0.95
56_E	60_D	1.140	0.95
181_G	185_M	1.138	0.94
460_R	477_M	1.138	0.94
461_E	464_I	1.137	0.94
254_A	258_T	1.135	0.94
69_L	659_V	1.133	0.94
380_I	432_I	1.132	0.94
552_G	599_V	1.131	0.94
183_D	189_E	1.130	0.94
261_D	268_A	1.123	0.94
557_G	660_V	1.121	0.94
512_D	521_V	1.119	0.94
521_V	533_F	1.115	0.94
564_D	614_R	1.106	0.94
55_F	62_A	1.106	0.94
174_M	178_Q	1.103	0.94
194_A	230_T	1.101	0.93
432_I	531_T	1.098	0.93
365_F	372_L	1.090	0.93
188_L	192_T	1.086	0.93
175_G	238_S	1.084	0.93
256_S	261_D	1.081	0.93
214_D	231_V	1.079	0.93
324_G	332_V	1.076	0.93
135_T	139_D	1.070	0.92
174_M	184_G	1.069	0.92
215_G	220_V	1.068	0.92
24_L	27_E	1.058	0.92
202_P	207_I	1.051	0.92
309_G	636_K	1.048	0.92
258_T	264_A	1.041	0.91
212_Y	216_F	1.040	0.91
58_A	98_L	1.039	0.91
16_V	94_I	1.032	0.91
258_T	261_D	1.024	0.91
226_E	230_T	1.018	0.90
184_G	191_A	1.018	0.90
254_A	261_D	1.016	0.90
317_T	339_L	1.015	0.90
265_D	269_D	1.014	0.90
134_T	138_G	1.014	0.90
418_P	422_E	1.011	0.90
262_A	266_D	1.006	0.90
15_H	18_S	1.006	0.90
522_S	536_T	1.004	0.90
238_S	242_V	0.998	0.90
44_H	47_K	0.997	0.89
257_G	260_A	0.996	0.89
547_L	611_V	0.993	0.89
280_S	283_G	0.993	0.89
563_V	611_V	0.991	0.89
279_S	282_G	0.988	0.89
260_A	266_D	0.983	0.89
272_G	277_S	0.980	0.89
182_V	187_V	0.979	0.89
15_H	49_N	0.978	0.89
214_D	217_E	0.977	0.89
439_D	536_T	0.977	0.89
259_E	267_D	0.970	0.88
261_D	280_S	0.969	0.88
282_G	285_S	0.965	0.88
265_D	280_S	0.964	0.88
61_L	94_I	0.964	0.88
191_A	197_L	0.963	0.88
321_L	335_E	0.963	0.88
610_L	623_H	0.961	0.88
466_K	491_F	0.959	0.88
484_D	511_R	0.955	0.87
558_I	622_V	0.955	0.87
172_I	176_D	0.954	0.87
459_M	486_V	0.954	0.87
5_L	55_F	0.944	0.87
215_G	222_T	0.940	0.87
550_E	628_R	0.939	0.86
128_D	271_A	0.938	0.86
481_D	484_D	0.937	0.86
137_S	274_T	0.934	0.86
187_V	192_T	0.934	0.86
547_L	563_V	0.934	0.86
172_I	183_D	0.933	0.86
228_S	231_V	0.933	0.86
466_K	482_V	0.932	0.86
362_V	565_E	0.931	0.86
50_F	59_S	0.930	0.86
235_P	238_S	0.929	0.86
156_D	160_I	0.924	0.86
460_R	621_A	0.923	0.86
556_Y	597_L	0.923	0.86
176_D	184_G	0.922	0.85
265_D	276_D	0.921	0.85
117_S	120_A	0.921	0.85
276_D	280_S	0.920	0.85
20_N	95_E	0.919	0.85
555_E	628_R	0.919	0.85
169_H	243_T	0.917	0.85
173_D	239_D	0.916	0.85
77_L	83_R	0.915	0.85
182_V	186_F	0.915	0.85
261_D	265_D	0.911	0.85
227_V	233_A	0.909	0.85
45_T	49_N	0.909	0.85
179_M	192_T	0.907	0.85
355_L	539_V	0.906	0.84
368_L	372_L	0.903	0.84
365_F	368_L	0.903	0.84
399_I	513_T	0.898	0.84
256_S	259_E	0.898	0.84
266_D	271_A	0.896	0.84
230_T	419_A	0.896	0.84
547_L	614_R	0.895	0.84
215_G	221_A	0.895	0.84
19_L	69_L	0.893	0.84
551_S	599_V	0.891	0.83
419_A	423_D	0.890	0.83
167_V	221_A	0.889	0.83
212_Y	231_V	0.887	0.83
325_M	332_V	0.886	0.83
541_V	634_V	0.886	0.83
206_A	256_S	0.883	0.83
383_V	433_T	0.882	0.83
231_V	236_K	0.881	0.83
254_A	259_E	0.879	0.83
41_R	44_H	0.878	0.83
275_A	278_G	0.875	0.82
169_H	217_E	0.873	0.82
229_D	232_A	0.873	0.82
120_A	124_E	0.873	0.82
91_I	95_E	0.872	0.82
214_D	218_L	0.866	0.82
124_E	127_G	0.865	0.82
318_R	546_V	0.861	0.81
201_E	207_I	0.857	0.81
189_E	192_T	0.857	0.81
412_D	501_S	0.856	0.81
92_D	367_R	0.855	0.81
265_D	273_T	0.855	0.81
49_N	53_M	0.855	0.81
168_Y	181_G	0.853	0.81
458_T	466_K	0.853	0.81
279_S	283_G	0.852	0.81
265_D	271_A	0.851	0.81
353_M	356_V	0.851	0.81
283_G	286_A	0.851	0.81
157_A	164_E	0.849	0.80
43_A	69_L	0.847	0.80
218_L	222_T	0.847	0.80
26_L	30_P	0.847	0.80
178_Q	183_D	0.847	0.80
260_A	264_A	0.846	0.80
458_T	465_E	0.846	0.80
264_A	267_D	0.845	0.80
260_A	268_A	0.844	0.80
379_D	418_P	0.844	0.80
511_R	515_T	0.842	0.80
259_E	262_A	0.842	0.80
209_D	212_Y	0.841	0.80
259_E	263_S	0.840	0.80
170_I	231_V	0.839	0.80
651_A	661_T	0.838	0.80
160_I	163_A	0.837	0.79
49_N	630_Q	0.837	0.79
267_D	276_D	0.835	0.79
37_D	509_V	0.834	0.79
36_M	649_S	0.831	0.79
263_S	269_D	0.829	0.79
170_I	174_M	0.829	0.79
556_Y	591_V	0.827	0.79
37_D	613_I	0.827	0.79
207_I	216_F	0.827	0.79
391_L	563_V	0.826	0.79
455_D	479_D	0.825	0.78
45_T	320_K	0.824	0.78
260_A	274_T	0.824	0.78
170_I	176_D	0.822	0.78
318_R	632_E	0.820	0.78
180_K	187_V	0.819	0.78
208_N	231_V	0.818	0.78
178_Q	184_G	0.817	0.78
262_A	265_D	0.817	0.78
212_Y	215_G	0.817	0.78
258_T	262_A	0.817	0.78
41_R	47_K	0.816	0.78
266_D	274_T	0.816	0.78
4_Y	52_A	0.815	0.78
3_D	10_R	0.815	0.78
216_F	222_T	0.815	0.78
172_I	184_G	0.813	0.77
47_K	66_E	0.811	0.77
258_T	278_G	0.811	0.77
59_S	62_A	0.811	0.77
310_L	349_T	0.809	0.77
174_M	183_D	0.809	0.77
170_I	227_V	0.805	0.77
266_D	272_G	0.805	0.77
276_D	281_S	0.802	0.76
179_M	189_E	0.801	0.76
455_D	483_E	0.801	0.76
202_P	213_G	0.801	0.76
548_F	557_G	0.798	0.76
181_G	231_V	0.797	0.76
597_L	647_G	0.797	0.76
395_I	400_S	0.796	0.76
427_D	431_T	0.794	0.76
304_L	639_E	0.793	0.76
93_G	114_T	0.791	0.75
494_N	500_V	0.791	0.75
12_G	98_L	0.791	0.75
277_S	280_S	0.791	0.75
609_M	627_V	0.791	0.75
253_D	256_S	0.790	0.75
355_L	621_A	0.790	0.75
262_A	270_D	0.789	0.75
270_D	275_A	0.789	0.75
208_N	213_G	0.789	0.75
362_V	584_D	0.788	0.75
216_F	219_V	0.787	0.75
183_D	192_T	0.787	0.75
4_Y	49_N	0.786	0.75
461_E	471_R	0.784	0.75
184_G	195_F	0.784	0.75
479_D	526_T	0.783	0.75
182_V	192_T	0.783	0.75
236_K	240_A	0.782	0.75
174_M	191_A	0.782	0.75
93_G	111_V	0.781	0.75
347_Q	633_V	0.781	0.75
158_D	276_D	0.781	0.75
168_Y	176_D	0.780	0.74
317_T	320_K	0.778	0.74
464_I	472_E	0.777	0.74
190_E	195_F	0.776	0.74
256_S	271_A	0.775	0.74
168_Y	191_A	0.775	0.74
173_D	176_D	0.775	0.74
237_L	242_V	0.774	0.74
345_S	406_L	0.772	0.74
267_D	271_A	0.771	0.74
18_S	42_T	0.771	0.74
524_D	532_T	0.771	0.74
22_A	38_E	0.770	0.74
45_T	641_I	0.768	0.73
347_Q	507_M	0.767	0.73
170_I	181_G	0.767	0.73
71_E	122_L	0.766	0.73
133_T	136_S	0.764	0.73
190_E	193_E	0.762	0.73
27_E	388_D	0.762	0.73
224_S	275_A	0.761	0.73
410_A	531_T	0.761	0.73
139_D	267_D	0.760	0.73
259_E	265_D	0.760	0.73
180_K	186_F	0.759	0.72
278_G	282_G	0.759	0.72
266_D	275_A	0.759	0.72
592_R	595_D	0.757	0.72
160_I	164_E	0.757	0.72
264_A	269_D	0.756	0.72
355_L	438_R	0.755	0.72
410_A	617_E	0.755	0.72
215_G	223_P	0.755	0.72
439_D	444_L	0.754	0.72
264_A	275_A	0.754	0.72
377_D	419_A	0.754	0.72
213_G	233_A	0.753	0.72
546_V	632_E	0.751	0.72
526_T	532_T	0.751	0.72
495_D	532_T	0.750	0.72
560_I	632_E	0.749	0.71
355_L	376_Q	0.749	0.71
494_N	498_T	0.749	0.71
268_A	279_S	0.748	0.71
79_V	83_R	0.748	0.71
196_D	221_A	0.746	0.71
263_S	266_D	0.743	0.71
499_D	537_L	0.742	0.71
274_T	281_S	0.741	0.71
44_H	63_H	0.740	0.71
24_L	88_F	0.739	0.70
4_Y	53_M	0.739	0.70
455_D	461_E	0.738	0.70
170_I	187_V	0.737	0.70
459_M	469_K	0.736	0.70
43_A	52_A	0.735	0.70
479_D	483_E	0.735	0.70
86_R	121_V	0.733	0.70
175_G	239_D	0.732	0.70
213_G	216_F	0.732	0.70
257_G	267_D	0.732	0.70
55_F	59_S	0.731	0.70
445_I	659_V	0.730	0.69
174_M	195_F	0.730	0.69
227_V	240_A	0.730	0.69
264_A	268_A	0.730	0.69
181_G	187_V	0.730	0.69
276_D	282_G	0.729	0.69
456_H	459_M	0.729	0.69
156_D	159_T	0.728	0.69
261_D	266_D	0.728	0.69
67_D	70_D	0.727	0.69
486_V	659_V	0.727	0.69
468_V	567_S	0.727	0.69
41_R	63_H	0.727	0.69
438_R	649_S	0.727	0.69
554_E	599_V	0.726	0.69
22_A	35_A	0.726	0.69
9_V	101_I	0.726	0.69
97_C	101_I	0.724	0.69
227_V	242_V	0.723	0.69
12_G	46_L	0.718	0.68
184_G	188_L	0.718	0.68
482_V	575_V	0.715	0.68
225_D	229_D	0.714	0.68
215_G	219_V	0.714	0.68
179_M	187_V	0.714	0.68
227_V	230_T	0.714	0.68
613_I	622_V	0.713	0.68
256_S	262_A	0.713	0.68
257_G	265_D	0.712	0.68
273_T	279_S	0.712	0.68
362_V	365_F	0.711	0.67
131_S	572_V	0.711	0.67
265_D	288_D	0.710	0.67
359_K	368_L	0.710	0.67
314_L	346_L	0.710	0.67
369_V	373_A	0.710	0.67
183_D	186_F	0.709	0.67
446_Q	532_T	0.707	0.67
256_S	273_T	0.707	0.67
227_V	234_F	0.707	0.67
513_T	521_V	0.706	0.67
57_D	101_I	0.706	0.67
220_V	223_P	0.705	0.67
397_T	513_T	0.704	0.67
111_V	115_I	0.703	0.67
257_G	264_A	0.702	0.66
278_G	285_S	0.701	0.66
391_L	543_I	0.701	0.66
323_R	656_E	0.701	0.66
434_L	565_E	0.700	0.66
39_I	43_A	0.699	0.66
184_G	189_E	0.698	0.66
544_V	639_E	0.697	0.66
274_T	277_S	0.695	0.66
10_R	297_V	0.693	0.65
47_K	63_H	0.692	0.65
324_G	335_E	0.691	0.65
268_A	273_T	0.691	0.65
208_N	234_F	0.691	0.65
611_V	624_C	0.689	0.65
394_T	498_T	0.689	0.65
125_V	136_S	0.687	0.65
199_G	209_D	0.685	0.65
50_F	55_F	0.684	0.64
259_E	274_T	0.684	0.64
580_V	655_G	0.684	0.64
594_G	605_N	0.683	0.64
60_D	415_I	0.678	0.64
61_L	65_V	0.678	0.64
270_D	273_T	0.678	0.64
123_D	127_G	0.678	0.64
101_I	107_V	0.678	0.64
472_E	475_Q	0.677	0.64
268_A	285_S	0.676	0.64
49_N	356_V	0.676	0.64
399_I	549_V	0.676	0.64
139_D	279_S	0.675	0.63
188_L	191_A	0.675	0.63
43_A	65_V	0.675	0.63
167_V	172_I	0.674	0.63
61_L	93_G	0.674	0.63
136_S	275_A	0.673	0.63
254_A	277_S	0.672	0.63
38_E	50_F	0.670	0.63
272_G	275_A	0.669	0.63
178_Q	181_G	0.669	0.63
24_L	371_D	0.669	0.63
440_R	491_F	0.667	0.63
458_T	462_K	0.666	0.62
555_E	658_D	0.664	0.62
52_A	69_L	0.663	0.62
132_G	137_S	0.663	0.62
424_N	427_D	0.662	0.62
269_D	272_G	0.662	0.62
320_K	404_M	0.661	0.62
187_V	190_E	0.661	0.62
441_D	546_V	0.659	0.62
261_D	271_A	0.659	0.62
209_D	213_G	0.657	0.61
206_A	211_E	0.657	0.61
389_V	440_R	0.657	0.61
310_L	544_V	0.655	0.61
280_S	285_S	0.655	0.61
347_Q	351_M	0.654	0.61
49_N	183_D	0.654	0.61
80_T	241_T	0.653	0.61
132_G	136_S	0.653	0.61
267_D	270_D	0.653	0.61
455_D	498_T	0.653	0.61
297_V	393_R	0.653	0.61
477_M	482_V	0.652	0.61
180_K	185_M	0.652	0.61
262_A	267_D	0.651	0.61
215_G	218_L	0.651	0.61
189_E	195_F	0.651	0.61
303_Q	513_T	0.649	0.60
396_L	541_V	0.649	0.60
542_A	635_V	0.648	0.60
129_G	266_D	0.647	0.60
44_H	48_G	0.647	0.60
19_L	350_V	0.647	0.60
44_H	66_E	0.646	0.60
174_M	186_F	0.646	0.60
112_T	455_D	0.646	0.60
283_G	289_N	0.646	0.60
256_S	264_A	0.645	0.60
53_M	308_H	0.645	0.60
367_R	371_D	0.645	0.60
254_A	268_A	0.645	0.60
173_D	203_S	0.645	0.60
136_S	259_E	0.644	0.60
175_G	179_M	0.644	0.60
231_V	239_D	0.641	0.59
547_L	651_A	0.641	0.59
211_E	221_A	0.640	0.59
170_I	191_A	0.640	0.59
82_D	268_A	0.639	0.59
310_L	415_I	0.638	0.59
49_N	52_A	0.638	0.59
319_I	393_R	0.638	0.59
256_S	267_D	0.636	0.59
465_E	496_E	0.636	0.59
253_D	261_D	0.636	0.59
281_S	600_P	0.635	0.59
216_F	231_V	0.635	0.59
564_D	659_V	0.633	0.59
172_I	175_G	0.632	0.58
401_D	513_T	0.632	0.58
34_E	108_D	0.630	0.58
19_L	39_I	0.629	0.58
288_D	455_D	0.629	0.58
181_G	197_L	0.629	0.58
99_D	103_A	0.627	0.58
230_T	234_F	0.627	0.58
15_H	45_T	0.625	0.58
158_D	161_D	0.624	0.57
169_H	193_E	0.623	0.57
364_K	584_D	0.623	0.57
271_A	277_S	0.621	0.57
172_I	182_V	0.621	0.57
637_P	642_L	0.621	0.57
445_I	572_V	0.620	0.57
628_R	660_V	0.619	0.57
104_T	108_D	0.618	0.57
184_G	207_I	0.616	0.56
272_G	286_A	0.616	0.56
355_L	389_V	0.616	0.56
230_T	236_K	0.616	0.56
664_D	667_T	0.616	0.56
651_A	659_V	0.616	0.56
254_A	273_T	0.616	0.56
389_V	541_V	0.615	0.56
21_N	591_V	0.615	0.56
172_I	178_Q	0.615	0.56
260_A	267_D	0.615	0.56
264_A	271_A	0.614	0.56
170_I	178_Q	0.613	0.56
58_A	97_C	0.613	0.56
412_D	508_D	0.613	0.56
581_I	621_A	0.612	0.56
186_F	195_F	0.612	0.56
207_I	211_E	0.612	0.56
171_H	175_G	0.610	0.56
431_T	458_T	0.610	0.56
406_L	651_A	0.610	0.56
258_T	272_G	0.610	0.56
286_A	289_N	0.609	0.56
315_V	597_L	0.609	0.56
257_G	278_G	0.609	0.56
636_K	655_G	0.608	0.55
136_S	273_T	0.608	0.55
181_G	195_F	0.608	0.55
225_D	235_P	0.607	0.55
253_D	260_A	0.607	0.55
303_Q	649_S	0.606	0.55
274_T	279_S	0.606	0.55
303_Q	352_D	0.606	0.55
262_A	282_G	0.605	0.55
566_I	609_M	0.605	0.55
543_I	634_V	0.605	0.55
262_A	268_A	0.605	0.55
545_K	557_G	0.605	0.55
278_G	283_G	0.604	0.55
315_V	347_Q	0.604	0.55
318_R	340_D	0.604	0.55
45_T	348_D	0.602	0.55
99_D	102_Q	0.602	0.55
17_T	21_N	0.602	0.55
560_I	630_Q	0.602	0.55
411_V	415_I	0.599	0.54
62_A	94_I	0.599	0.54
68_L	480_D	0.598	0.54
52_A	62_A	0.597	0.54
155_V	160_I	0.597	0.54
270_D	283_G	0.597	0.54
230_T	240_A	0.594	0.54
113_G	117_S	0.592	0.54
165_D	223_P	0.592	0.54
234_F	242_V	0.592	0.54
462_K	468_V	0.592	0.54
316_T	631_E	0.591	0.53
231_V	242_V	0.591	0.53
225_D	232_A	0.590	0.53
257_G	262_A	0.590	0.53
52_A	59_S	0.590	0.53
281_S	285_S	0.589	0.53
592_R	608_G	0.589	0.53
438_R	539_V	0.588	0.53
274_T	278_G	0.588	0.53
161_D	263_S	0.588	0.53
55_F	101_I	0.587	0.53
276_D	289_N	0.587	0.53
315_V	647_G	0.586	0.53
129_G	206_A	0.585	0.53
20_N	513_T	0.584	0.53
406_L	533_F	0.584	0.53
347_Q	566_I	0.582	0.52
344_S	632_E	0.581	0.52
119_R	123_D	0.581	0.52
441_D	541_V	0.580	0.52
155_V	158_D	0.580	0.52
496_E	553_G	0.580	0.52
266_D	282_G	0.580	0.52
192_T	195_F	0.580	0.52
441_D	513_T	0.578	0.52
197_L	218_L	0.578	0.52
382_F	432_I	0.578	0.52
415_I	418_P	0.577	0.52
260_A	263_S	0.576	0.52
395_I	517_L	0.576	0.52
62_A	391_L	0.576	0.52
214_D	227_V	0.576	0.52
321_L	339_L	0.575	0.51
171_H	177_S	0.574	0.51
263_S	268_A	0.574	0.51
227_V	236_K	0.574	0.51
455_D	495_D	0.573	0.51
182_V	185_M	0.573	0.51
69_L	446_Q	0.572	0.51
268_A	280_S	0.572	0.51
457_D	479_D	0.570	0.51
77_L	455_D	0.570	0.51
560_I	635_V	0.570	0.51
281_S	286_A	0.570	0.51
184_G	192_T	0.569	0.51
432_I	602_E	0.569	0.51
411_V	418_P	0.569	0.51
554_E	662_I	0.568	0.51
228_S	232_A	0.568	0.51
62_A	406_L	0.568	0.51
50_F	627_V	0.567	0.50
211_E	215_G	0.567	0.50
261_D	282_G	0.567	0.50
104_T	107_V	0.566	0.50
264_A	272_G	0.566	0.50
100_E	107_V	0.564	0.50
159_T	164_E	0.564	0.50
116_E	131_S	0.563	0.50
202_P	222_T	0.563	0.50
73_R	509_V	0.563	0.50
484_D	488_H	0.562	0.50
594_G	608_G	0.562	0.50
88_F	659_V	0.560	0.50
183_D	190_E	0.560	0.50
465_E	638_F	0.558	0.49
540_T	634_V	0.558	0.49
68_L	432_I	0.558	0.49
27_E	371_D	0.558	0.49
410_A	495_D	0.558	0.49
275_A	285_S	0.557	0.49
275_A	281_S	0.557	0.49
40_F	63_H	0.557	0.49
56_E	411_V	0.555	0.49
123_D	126_D	0.555	0.49
181_G	189_E	0.554	0.49
118_V	121_V	0.554	0.49
311_V	348_D	0.554	0.49
376_Q	627_V	0.553	0.49
181_G	234_F	0.552	0.49
521_V	637_P	0.551	0.48
104_T	331_E	0.551	0.48
216_F	221_A	0.550	0.48
324_G	558_I	0.550	0.48
320_K	632_E	0.550	0.48
398_E	642_L	0.549	0.48
125_V	129_G	0.549	0.48
311_V	346_L	0.549	0.48
81_S	553_G	0.548	0.48
267_D	273_T	0.547	0.48
480_D	484_D	0.547	0.48
171_H	262_A	0.547	0.48
257_G	266_D	0.547	0.48
301_V	518_D	0.547	0.48
499_D	514_V	0.547	0.48
438_R	541_V	0.545	0.48
359_K	645_I	0.545	0.48
182_V	210_G	0.544	0.48
34_E	37_D	0.544	0.48
191_A	196_D	0.544	0.48
135_T	419_A	0.544	0.48
304_L	314_L	0.544	0.48
634_V	662_I	0.544	0.48
312_E	507_M	0.544	0.48
159_T	162_A	0.543	0.47
81_S	374_R	0.543	0.47
363_G	410_A	0.543	0.47
572_V	579_E	0.543	0.47
262_A	279_S	0.542	0.47
261_D	272_G	0.542	0.47
136_S	269_D	0.542	0.47
356_V	631_E	0.542	0.47
321_L	336_L	0.542	0.47
398_E	513_T	0.541	0.47
564_D	619_Q	0.541	0.47
130_G	203_S	0.541	0.47
271_A	283_G	0.541	0.47
229_D	259_E	0.540	0.47
273_T	278_G	0.540	0.47
226_E	272_G	0.540	0.47
270_D	274_T	0.540	0.47
428_R	431_T	0.540	0.47
303_Q	344_S	0.540	0.47
459_M	495_D	0.540	0.47
12_G	15_H	0.538	0.47
135_T	138_G	0.538	0.47
174_M	181_G	0.537	0.47
282_G	457_D	0.537	0.47
172_I	192_T	0.537	0.47
552_G	602_E	0.537	0.47
376_Q	500_V	0.535	0.46
164_E	167_V	0.535	0.46
46_L	513_T	0.535	0.46
346_L	434_L	0.534	0.46
333_L	659_V	0.534	0.46
168_Y	174_M	0.533	0.46
126_D	286_A	0.533	0.46
63_H	66_E	0.532	0.46
380_I	618_R	0.532	0.46
68_L	77_L	0.531	0.46
333_L	591_V	0.531	0.46
45_T	630_Q	0.531	0.46
268_A	271_A	0.531	0.46
320_K	345_S	0.531	0.46
518_D	652_A	0.530	0.46
138_G	200_A	0.530	0.46
553_G	601_D	0.530	0.46
281_S	284_S	0.529	0.46
92_D	371_D	0.529	0.46
133_T	274_T	0.527	0.46
269_D	285_S	0.527	0.46
233_A	236_K	0.525	0.45
269_D	289_N	0.525	0.45
342_I	394_T	0.525	0.45
271_A	274_T	0.525	0.45
260_A	602_E	0.525	0.45
168_Y	184_G	0.524	0.45
262_A	275_A	0.524	0.45
427_D	455_D	0.522	0.45
7_A	15_H	0.522	0.45
311_V	542_A	0.521	0.45
82_D	261_D	0.520	0.45
218_L	231_V	0.520	0.45
302_D	306_E	0.520	0.45
41_R	66_E	0.520	0.45
312_E	614_R	0.519	0.45
437_E	444_L	0.519	0.45
260_A	265_D	0.518	0.44
433_T	447_V	0.518	0.44
257_G	274_T	0.518	0.44
10_R	373_A	0.518	0.44
317_T	335_E	0.518	0.44
171_H	215_G	0.518	0.44
342_I	653_V	0.517	0.44
51_G	509_V	0.517	0.44
181_G	192_T	0.517	0.44
23_L	481_D	0.517	0.44
560_I	638_F	0.516	0.44
258_T	265_D	0.516	0.44
243_T	261_D	0.516	0.44
187_V	237_L	0.516	0.44
266_D	269_D	0.515	0.44
551_S	594_G	0.515	0.44
549_V	558_I	0.514	0.44
258_T	274_T	0.514	0.44
639_E	659_V	0.514	0.44
170_I	220_V	0.514	0.44
170_I	202_P	0.514	0.44
383_V	410_A	0.513	0.44
418_P	447_V	0.513	0.44
258_T	289_N	0.512	0.44
286_A	290_T	0.512	0.44
101_I	399_I	0.512	0.44
272_G	279_S	0.512	0.44
133_T	262_A	0.511	0.44
220_V	224_S	0.511	0.44
283_G	478_P	0.511	0.44
14_E	72_M	0.511	0.44
180_K	189_E	0.511	0.44
115_I	119_R	0.510	0.43
137_S	495_D	0.509	0.43
23_L	87_I	0.509	0.43
100_E	105_G	0.509	0.43
233_A	242_V	0.509	0.43
213_G	231_V	0.508	0.43
82_D	423_D	0.507	0.43
637_P	645_I	0.507	0.43
132_G	240_A	0.507	0.43
129_G	282_G	0.507	0.43
464_I	475_Q	0.507	0.43
336_L	345_S	0.507	0.43
264_A	279_S	0.506	0.43
339_L	343_T	0.505	0.43
355_L	371_D	0.504	0.43
397_T	531_T	0.504	0.43
257_G	261_D	0.504	0.43
213_G	227_V	0.504	0.43
369_V	432_I	0.503	0.43
136_S	264_A	0.503	0.43
98_L	616_S	0.503	0.43
25_E	28_S	0.503	0.43
69_L	642_L	0.503	0.43
269_D	287_I	0.502	0.42
202_P	227_V	0.502	0.42
209_D	231_V	0.502	0.42
24_L	310_L	0.501	0.42
318_R	545_K	0.501	0.42
166_P	170_I	0.501	0.42
70_D	73_R	0.501	0.42
265_D	274_T	0.500	0.42
515_T	621_A	0.500	0.42
364_K	395_I	0.500	0.42

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
1b3qA	2	0.5614	100	0.528	Contact Map
2lp4A	1	0.3263	100	0.84	Contact Map
1i58A	2	0.2829	100	0.841	Contact Map
1i5nA	1	0.1916	100	0.864	Contact Map
3kyjA	1	0.1886	99.9	0.867	Contact Map
2ld6A	1	0.1946	99.9	0.868	Contact Map
2lchA	1	0.1647	99.9	0.879	Contact Map
4jpbW	1	0.1886	99.9	0.881	Contact Map
2ho9A	1	0.2096	99.9	0.887	Contact Map
2qdlA	1	0.2021	99.9	0.887	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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