GREMLIN Database
Q9HQW5 - Chemotaxis protein
UniProt: Q9HQW5 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 178 (142)
Sequences: 4408 (3087)
Seq/√Len: 259.1

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
25_V154_A4.0691.00
114_D137_R3.5951.00
83_I96_G3.2861.00
15_H107_G3.2251.00
108_Y136_I2.9861.00
53_E67_D2.9741.00
113_I134_G2.8681.00
34_D87_D2.7491.00
35_S59_R2.6181.00
53_E98_R2.5821.00
32_A162_D2.5681.00
53_E70_E2.5031.00
109_A112_Q2.3901.00
20_K101_E2.3861.00
86_L97_L2.2911.00
69_R100_A2.2551.00
65_I83_I2.0331.00
133_R160_D2.0231.00
70_E76_G1.9831.00
39_S42_V1.9781.00
130_E163_K1.9701.00
57_D60_G1.9261.00
14_A29_D1.7601.00
38_E82_N1.7171.00
57_D62_T1.7081.00
12_E110_E1.5691.00
61_E94_K1.5621.00
132_V157_L1.5561.00
138_K154_A1.5151.00
50_D70_E1.5021.00
20_K103_T1.4841.00
39_S98_R1.4791.00
139_G154_A1.4731.00
14_A110_E1.3981.00
113_I158_W1.3981.00
39_S83_I1.3971.00
16_V158_W1.3931.00
65_I96_G1.3721.00
17_V82_N1.3381.00
112_Q138_K1.3321.00
17_V84_L1.3271.00
29_D133_R1.3021.00
68_P164_L1.3011.00
40_K83_I1.2821.00
11_E111_H1.2631.00
18_E25_V1.2441.00
28_I86_L1.2271.00
34_D61_E1.2111.00
71_F169_S1.2031.00
56_M83_I1.1801.00
63_T85_V1.1481.00
22_G69_R1.1411.00
81_D98_R1.1271.00
67_D71_F1.1111.00
29_D32_A1.1071.00
19_F84_L1.0971.00
18_E106_S1.0851.00
67_D76_G1.0811.00
136_I158_W1.0721.00
16_V136_I1.0651.00
25_V103_T1.0591.00
58_L85_V1.0561.00
33_V84_L1.0501.00
34_D94_K1.0351.00
138_K156_V1.0331.00
22_G74_I1.0191.00
37_V83_I1.0041.00
32_A133_R1.0011.00
67_D70_E0.9901.00
20_K23_D0.9891.00
69_R74_I0.9801.00
117_S120_D0.9761.00
27_A158_W0.9761.00
86_L161_I0.9631.00
18_E103_T0.9491.00
16_V108_Y0.9491.00
37_V58_L0.9341.00
28_I161_I0.9251.00
12_E109_A0.9191.00
13_A110_E0.9091.00
87_D94_K0.9061.00
19_F35_S0.9021.00
163_K166_G0.8901.00
97_L161_I0.8871.00
17_V36_I0.8831.00
160_D163_K0.8821.00
81_D100_A0.8781.00
68_P97_L0.8661.00
13_A107_G0.8500.99
88_R91_D0.8500.99
42_V65_I0.8490.99
39_S82_N0.8480.99
21_L68_P0.8470.99
30_I37_V0.8330.99
69_R75_H0.8290.99
19_F28_I0.8250.99
51_A71_F0.8250.99
140_A154_A0.7850.99
20_K106_S0.7720.99
38_E155_L0.7710.99
45_V55_V0.7650.99
55_V157_L0.7620.99
100_A105_V0.7580.99
84_L99_V0.7420.99
91_D162_D0.7420.99
83_I98_R0.7280.98
166_G169_S0.7270.98
13_A109_A0.7240.98
120_D126_A0.7170.98
37_V102_V0.7170.98
12_E111_H0.7150.98
14_A133_R0.7150.98
106_S154_A0.7130.98
32_A161_I0.7080.98
28_I33_V0.7040.98
10_V91_D0.7030.98
52_V66_V0.7030.98
73_A129_S0.7000.98
37_V40_K0.6980.98
43_T57_D0.6980.98
165_I169_S0.6970.98
18_E104_E0.6870.98
19_F72_L0.6850.98
27_A136_I0.6830.98
42_V85_V0.6820.98
42_V58_L0.6810.98
37_V61_E0.6800.98
53_E76_G0.6770.97
37_V104_E0.6650.97
15_H30_I0.6640.97
163_K167_S0.6570.97
116_G132_V0.6560.97
42_V56_M0.6510.97
30_I105_V0.6440.97
92_K111_H0.6430.97
17_V38_E0.6430.97
137_R155_L0.6430.97
135_V155_L0.6430.97
27_A156_V0.6340.96
45_V119_L0.6320.96
39_S81_D0.6320.96
62_T155_L0.6300.96
35_S102_V0.6280.96
12_E50_D0.6220.96
77_D100_A0.6200.96
11_E109_A0.6150.96
41_Q88_R0.6150.96
28_I88_R0.6130.95
55_V135_V0.6120.95
31_A34_D0.6100.95
112_Q136_I0.6100.95
56_M65_I0.6090.95
63_T94_K0.6080.95
54_G159_L0.6010.95
17_V135_V0.6010.95
69_R76_G0.6000.95
26_C72_L0.5950.95
71_F131_L0.5950.95
45_V48_A0.5940.95
32_A160_D0.5910.94
37_V56_M0.5840.94
43_T62_T0.5830.94
18_E27_A0.5810.94
38_E135_V0.5790.94
69_R98_R0.5730.94
56_M105_V0.5720.93
129_S163_K0.5710.93
75_H78_H0.5700.93
165_I170_A0.5630.93
10_V13_A0.5620.93
82_N135_V0.5610.93
16_V27_A0.5610.93
42_V83_I0.5590.93
16_V110_E0.5580.93
71_F117_S0.5580.93
56_M85_V0.5560.92
30_I66_V0.5530.92
93_Q165_I0.5510.92
20_K25_V0.5500.92
88_R159_L0.5470.92
18_E156_V0.5470.92
21_L74_I0.5450.92
48_A51_A0.5440.92
108_Y113_I0.5430.92
43_T60_G0.5430.92
43_T155_L0.5410.91
86_L164_L0.5410.91
134_G157_L0.5400.91
99_V155_L0.5380.91
62_T157_L0.5380.91
18_E102_V0.5370.91
28_I97_L0.5370.91
134_G158_W0.5370.91
112_Q137_R0.5320.91
15_H37_V0.5290.91
21_L39_S0.5250.90
166_G170_A0.5220.90
67_D77_D0.5220.90
36_I45_V0.5200.90
45_V114_D0.5190.90
21_L69_R0.5180.90
51_A70_E0.5170.90
38_E105_V0.5160.89
55_V102_V0.5140.89
74_I77_D0.5140.89
10_V140_A0.5140.89
107_G110_E0.5130.89
23_D77_D0.5120.89
94_K140_A0.5100.89
37_V137_R0.5060.89
52_V64_A0.5060.89
82_N104_E0.5020.88
83_I114_D0.5000.88
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
2ho9A 1 0.8933 100 0.266 Contact Map
2qdlA 1 0.8596 100 0.279 Contact Map
4jpbW 1 0.7753 99.9 0.305 Contact Map
1b3qA 2 0.7697 99.4 0.615 Contact Map
4o0aA 1 0.6348 4.7 0.939 Contact Map
1wi9A 1 0.3933 4.4 0.94 Contact Map
2xheA 1 0.2809 4.1 0.941 Contact Map
1epuA 1 0.3258 4.1 0.941 Contact Map
4jehA 2 0.3596 3.1 0.944 Contact Map
4ccaA 1 0.3371 2.5 0.947 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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