Q9HQV5 - HALSA - GREMLIN Contacts

Home
GREMLIN
- Submit - Monomer
- Submit - Complex
Contacts
Metagenomics
- Contacts
- Structures
Structures
- List
Old Projects
- Complexes (2014)
- PFAM (2013)

Q9HQV5 - Uncharacterized protein

UniProt:	Q9HQV5	Sequences: MTTDLKPIDPQEAKEWYLENRRGELADATYKAHKYRLSPFVEWCDTEGDVSNMNDLSGRHFHQYKKWRRENGDCNKVTMATQLSTLKVFIDFCESIDAVRPGLSDYIDPPTMKNKEDVNDDYVDAETAQAIIDYQRNFNYSQREHVIFELLWHTGMRNGALRAVDLDDYDNEERTLEVHHRPDQDTPLKNGKEGQRVVSLKPKVNQIVRDYIDHHRFGKTDESGREPLLTTRQGRISKTSIRSNCYRATRPCEYGLGCPHDRNPDDCDAASSYHAASKCPSSHASHSLRKGAITHARRSEVPIEAVSERMDVSADVLKKHYDKRTKKQEMKNRRGYFDNI	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	340 (275)
Sequences:	35692 (28659)
Seq/√Len:	1728.2

ECOLI - INTQ INTR XERC XERD INTB INTF INTA INTZ INTD INTS INTE FIME FIMB
BACSU - INT XERC XERD YOMM YOPP YOEC
HALSA - Q9HQV5 Q9HR66 Q9HSI7 O54590 O52010
SULSO - Q980D9

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
293_I	310_M	5.098	1.00
166_L	212_I	3.335	1.00
57_S	60_H	3.310	1.00
196_R	311_D	3.137	1.00
284_A	287_S	2.738	1.00
155_G	292_A	2.724	1.00
158_N	286_H	2.634	1.00
151_L	285_S	2.618	1.00
292_A	309_R	2.545	1.00
68_R	82_Q	2.522	1.00
165_D	235_R	2.252	1.00
177_E	197_V	2.236	1.00
174_R	205_N	2.230	1.00
165_D	227_P	2.195	1.00
151_L	161_L	2.193	1.00
191_G	194_G	2.174	1.00
312_V	318_K	2.062	1.00
36_R	81_T	2.052	1.00
146_V	211_Y	2.045	1.00
290_K	323_K	2.042	1.00
124_D	127_T	2.025	1.00
165_D	226_E	2.010	1.00
175_T	197_V	1.977	1.00
302_P	305_A	1.944	1.00
153_H	201_K	1.885	1.00
297_R	306_V	1.868	1.00
205_N	209_R	1.867	1.00
170_D	173_E	1.846	1.00
65_K	83_L	1.838	1.00
304_E	307_S	1.813	1.00
36_R	85_T	1.809	1.00
92_F	96_I	1.794	1.00
34_K	38_S	1.783	1.00
39_P	82_Q	1.775	1.00
160_A	196_R	1.691	1.00
199_S	309_R	1.690	1.00
194_G	313_S	1.681	1.00
14_K	37_L	1.673	1.00
61_F	104_S	1.645	1.00
310_M	318_K	1.595	1.00
144_E	244_N	1.595	1.00
156_M	161_L	1.585	1.00
145_H	149_E	1.579	1.00
18_L	34_K	1.578	1.00
296_A	301_V	1.569	1.00
316_V	319_K	1.567	1.00
125_A	295_H	1.559	1.00
292_A	296_A	1.554	1.00
56_L	90_I	1.501	1.00
298_R	328_Q	1.500	1.00
171_N	209_R	1.492	1.00
14_K	89_F	1.488	1.00
200_L	205_N	1.480	1.00
297_R	322_D	1.478	1.00
165_D	168_D	1.462	1.00
149_E	207_I	1.451	1.00
166_L	228_L	1.439	1.00
52_N	55_D	1.426	1.00
29_T	33_H	1.423	1.00
77_V	81_T	1.416	1.00
317_L	320_H	1.413	1.00
123_V	291_G	1.401	1.00
147_I	241_I	1.394	1.00
28_A	31_K	1.392	1.00
170_D	175_T	1.387	1.00
89_F	93_C	1.386	1.00
158_N	162_R	1.383	1.00
156_M	178_V	1.382	1.00
158_N	238_K	1.382	1.00
307_S	315_D	1.381	1.00
152_W	295_H	1.372	1.00
304_E	308_E	1.368	1.00
13_A	93_C	1.358	1.00
135_Q	248_A	1.357	1.00
128_A	152_W	1.356	1.00
153_H	204_V	1.355	1.00
27_D	31_K	1.355	1.00
11_Q	15_E	1.353	1.00
296_A	306_V	1.347	1.00
294_T	323_K	1.345	1.00
168_D	179_H	1.340	1.00
127_T	130_A	1.334	1.00
69_R	79_M	1.325	1.00
167_D	226_E	1.295	1.00
227_P	235_R	1.293	1.00
64_Y	82_Q	1.291	1.00
48_G	60_H	1.290	1.00
238_K	242_R	1.271	1.00
136_R	145_H	1.268	1.00
159_G	163_A	1.252	1.00
181_R	191_G	1.250	1.00
31_K	35_Y	1.236	1.00
146_V	207_I	1.224	1.00
132_I	149_E	1.223	1.00
16_W	20_N	1.218	1.00
40_F	43_W	1.214	1.00
147_I	161_L	1.208	1.00
13_A	92_F	1.202	1.00
146_V	210_D	1.199	1.00
91_D	105_D	1.197	1.00
179_H	195_Q	1.188	1.00
174_R	202_P	1.186	1.00
152_W	288_L	1.169	1.00
291_G	295_H	1.169	1.00
83_L	87_K	1.167	1.00
64_Y	68_R	1.166	1.00
129_Q	133_D	1.166	1.00
125_A	299_S	1.158	1.00
78_T	82_Q	1.150	1.00
164_V	176_L	1.150	1.00
239_T	242_R	1.148	1.00
237_S	240_S	1.147	1.00
123_V	283_H	1.146	1.00
307_S	318_K	1.138	1.00
128_A	295_H	1.137	1.00
298_R	325_T	1.137	1.00
65_K	69_R	1.133	1.00
43_W	67_W	1.130	1.00
94_E	99_V	1.126	1.00
80_A	110_P	1.121	1.00
18_L	30_Y	1.121	1.00
240_S	243_S	1.120	1.00
293_I	306_V	1.112	1.00
245_C	249_T	1.111	1.00
17_Y	88_V	1.110	1.00
157_R	286_H	1.102	1.00
158_N	242_R	1.096	1.00
134_Y	251_P	1.093	1.00
62_H	66_K	1.091	1.00
75_N	78_T	1.086	1.00
314_A	319_K	1.078	1.00
314_A	317_L	1.077	1.00
244_N	247_R	1.076	1.00
147_I	229_L	1.075	1.00
130_A	134_Y	1.072	1.00
249_T	283_H	1.070	1.00
97_D	101_P	1.056	1.00
177_E	195_Q	1.056	1.00
202_P	206_Q	1.055	1.00
30_Y	34_K	1.054	1.00
134_Y	252_C	1.051	1.00
13_A	53_M	1.049	1.00
123_V	131_I	1.049	1.00
43_W	63_Q	1.045	1.00
328_Q	331_K	1.036	1.00
201_K	204_V	1.034	1.00
32_A	36_R	1.033	1.00
122_Y	291_G	1.026	1.00
36_R	82_Q	1.021	1.00
292_A	310_M	1.019	1.00
33_H	85_T	1.010	1.00
150_L	176_L	1.009	1.00
242_R	246_Y	1.004	1.00
32_A	35_Y	0.996	1.00
162_R	238_K	0.991	1.00
152_W	291_G	0.990	1.00
62_H	96_I	0.988	1.00
167_D	225_R	0.986	1.00
90_I	99_V	0.984	1.00
35_Y	39_P	0.982	1.00
28_A	32_A	0.974	1.00
74_C	82_Q	0.971	1.00
25_L	30_Y	0.965	1.00
294_T	322_D	0.965	1.00
153_H	203_K	0.961	1.00
26_A	29_T	0.954	1.00
149_E	203_K	0.952	1.00
293_I	322_D	0.951	1.00
11_Q	42_E	0.949	1.00
69_R	76_K	0.945	1.00
150_L	229_L	0.942	1.00
135_Q	148_F	0.942	1.00
95_S	108_D	0.931	1.00
22_R	30_Y	0.931	1.00
142_Q	210_D	0.930	1.00
246_Y	282_S	0.922	1.00
227_P	230_T	0.919	1.00
308_E	329_E	0.919	1.00
145_H	207_I	0.918	1.00
125_A	129_Q	0.918	1.00
203_K	206_Q	0.917	1.00
43_W	64_Y	0.916	1.00
87_K	91_D	0.911	1.00
123_V	127_T	0.911	1.00
91_D	102_G	0.910	1.00
90_I	103_L	0.910	1.00
330_M	334_R	0.907	1.00
247_R	251_P	0.906	1.00
295_H	298_R	0.903	1.00
127_T	281_S	0.899	1.00
58_G	62_H	0.893	1.00
93_C	98_A	0.892	1.00
125_A	298_R	0.890	1.00
146_V	229_L	0.886	1.00
40_F	90_I	0.883	1.00
122_Y	323_K	0.873	1.00
246_Y	250_R	0.866	1.00
58_G	95_S	0.864	1.00
15_E	19_E	0.864	1.00
293_I	297_R	0.863	1.00
170_D	177_E	0.862	1.00
25_L	33_H	0.854	1.00
67_W	71_N	0.852	1.00
27_D	30_Y	0.849	1.00
68_R	79_M	0.848	1.00
179_H	193_E	0.840	1.00
248_A	251_P	0.837	1.00
38_S	42_E	0.835	1.00
121_D	287_S	0.833	1.00
11_Q	46_T	0.829	1.00
81_T	84_S	0.828	1.00
95_S	106_Y	0.828	1.00
74_C	78_T	0.826	1.00
16_W	98_A	0.825	1.00
171_N	205_N	0.824	1.00
32_A	81_T	0.822	1.00
290_K	320_H	0.819	1.00
90_I	104_S	0.818	1.00
150_L	204_V	0.818	1.00
242_R	285_S	0.813	1.00
63_Q	67_W	0.813	1.00
162_R	241_I	0.812	1.00
303_I	319_K	0.810	1.00
68_R	74_C	0.809	1.00
158_N	241_I	0.806	1.00
102_G	105_D	0.800	1.00
327_K	331_K	0.798	1.00
94_E	102_G	0.797	1.00
40_F	45_D	0.795	1.00
154_T	198_V	0.792	1.00
164_V	169_Y	0.790	1.00
210_D	214_H	0.788	1.00
301_V	305_A	0.787	1.00
142_Q	214_H	0.785	1.00
305_A	332_N	0.784	1.00
134_Y	248_A	0.783	1.00
60_H	63_Q	0.782	1.00
314_A	318_K	0.779	1.00
37_L	42_E	0.777	1.00
74_C	79_M	0.774	1.00
307_S	319_K	0.774	1.00
83_L	104_S	0.768	1.00
156_M	176_L	0.766	1.00
200_L	204_V	0.766	1.00
11_Q	47_E	0.763	1.00
15_E	34_K	0.762	1.00
155_G	310_M	0.760	1.00
16_W	19_E	0.756	1.00
204_V	207_I	0.750	1.00
209_R	213_D	0.748	1.00
14_K	18_L	0.739	1.00
45_D	48_G	0.738	1.00
41_V	45_D	0.733	1.00
13_A	89_F	0.733	1.00
58_G	97_D	0.731	1.00
315_D	319_K	0.728	1.00
158_N	285_S	0.725	1.00
209_R	212_I	0.723	1.00
150_L	161_L	0.722	1.00
315_D	318_K	0.717	1.00
298_R	327_K	0.716	1.00
94_E	105_D	0.716	1.00
47_E	60_H	0.713	1.00
151_L	158_N	0.711	1.00
59_R	63_Q	0.705	1.00
93_C	99_V	0.705	1.00
66_K	69_R	0.704	1.00
243_S	247_R	0.702	1.00
240_S	244_N	0.701	1.00
39_P	64_Y	0.701	1.00
13_A	96_I	0.699	1.00
293_I	312_V	0.698	1.00
56_L	61_F	0.698	1.00
305_A	309_R	0.697	1.00
297_R	325_T	0.695	1.00
97_D	106_Y	0.691	1.00
331_K	334_R	0.690	1.00
164_V	228_L	0.690	1.00
244_N	248_A	0.687	1.00
293_I	318_K	0.686	1.00
35_Y	38_S	0.685	1.00
130_A	133_D	0.684	1.00
206_Q	210_D	0.682	1.00
144_E	248_A	0.679	1.00
239_T	246_Y	0.678	1.00
123_V	287_S	0.676	1.00
71_N	74_C	0.676	1.00
126_E	130_A	0.672	1.00
170_D	174_R	0.672	1.00
246_Y	249_T	0.672	1.00
150_L	156_M	0.671	1.00
77_V	80_A	0.670	1.00
61_F	86_L	0.669	1.00
135_Q	145_H	0.665	1.00
245_C	285_S	0.664	1.00
245_C	288_L	0.663	1.00
206_Q	209_R	0.661	1.00
59_R	96_I	0.657	1.00
131_I	249_T	0.657	1.00
131_I	148_F	0.653	1.00
142_Q	146_V	0.653	1.00
65_K	79_M	0.652	1.00
40_F	64_Y	0.649	1.00
89_F	92_F	0.647	1.00
309_R	329_E	0.645	1.00
297_R	304_E	0.645	1.00
283_H	287_S	0.645	1.00
40_F	86_L	0.638	1.00
44_C	67_W	0.638	1.00
303_I	315_D	0.636	1.00
66_K	70_E	0.635	1.00
301_V	306_V	0.635	1.00
87_K	104_S	0.635	1.00
136_R	149_E	0.635	1.00
142_Q	145_H	0.633	1.00
62_H	65_K	0.632	1.00
90_I	94_E	0.630	1.00
149_E	204_V	0.629	1.00
94_E	101_P	0.628	1.00
12_E	16_W	0.626	1.00
91_D	94_E	0.622	1.00
241_I	285_S	0.619	1.00
146_V	150_L	0.618	1.00
207_I	210_D	0.617	1.00
325_T	328_Q	0.611	1.00
154_T	201_K	0.610	1.00
80_A	84_S	0.608	1.00
40_F	71_N	0.606	1.00
126_E	129_Q	0.605	1.00
16_W	92_F	0.605	1.00
301_V	332_N	0.603	1.00
148_F	288_L	0.601	1.00
37_L	89_F	0.601	1.00
43_W	46_T	0.600	1.00
297_R	302_P	0.598	1.00
211_Y	214_H	0.598	1.00
12_E	15_E	0.597	1.00
297_R	303_I	0.597	1.00
157_R	180_H	0.596	1.00
208_V	228_L	0.595	1.00
45_D	64_Y	0.595	1.00
304_E	319_K	0.594	1.00
146_V	208_V	0.592	1.00
132_I	145_H	0.589	1.00
15_E	42_E	0.588	1.00
64_Y	86_L	0.584	1.00
191_G	195_Q	0.584	1.00
239_T	243_S	0.583	1.00
125_A	291_G	0.583	1.00
326_K	329_E	0.582	1.00
156_M	160_A	0.582	1.00
87_K	105_D	0.582	1.00
286_H	290_K	0.581	1.00
122_Y	294_T	0.579	1.00
128_A	132_I	0.576	1.00
128_A	291_G	0.576	1.00
169_Y	176_L	0.576	1.00
287_S	290_K	0.574	1.00
146_V	204_V	0.573	1.00
40_F	44_C	0.573	1.00
37_L	85_T	0.571	1.00
248_A	252_C	0.570	1.00
306_V	322_D	0.568	1.00
163_A	235_R	0.562	1.00
76_K	80_A	0.561	1.00
327_K	330_M	0.559	1.00
48_G	55_D	0.558	1.00
94_E	106_Y	0.558	1.00
169_Y	208_V	0.558	1.00
64_Y	67_W	0.557	1.00
92_F	98_A	0.555	1.00
297_R	324_R	0.554	1.00
83_L	107_I	0.554	1.00
307_S	314_A	0.552	1.00
120_D	284_A	0.551	1.00
87_K	109_P	0.550	1.00
16_W	96_I	0.550	1.00
202_P	334_R	0.548	1.00
165_D	225_R	0.547	1.00
149_E	153_H	0.546	1.00
143_R	211_Y	0.544	1.00
137_N	141_S	0.544	1.00
307_S	317_L	0.543	1.00
86_L	104_S	0.543	1.00
181_R	192_K	0.541	1.00
53_M	93_C	0.540	1.00
166_L	208_V	0.540	1.00
20_N	92_F	0.539	1.00
58_G	96_I	0.532	1.00
160_A	311_D	0.528	1.00
104_S	107_I	0.528	1.00
42_E	45_D	0.526	1.00
120_D	290_K	0.525	1.00
151_L	288_L	0.524	1.00
17_Y	92_F	0.520	1.00
150_L	208_V	0.518	1.00
223_S	226_E	0.517	1.00
21_R	25_L	0.516	1.00
123_V	128_A	0.515	1.00
199_S	330_M	0.513	1.00
67_W	70_E	0.513	1.00
43_W	47_E	0.512	1.00
143_R	146_V	0.510	1.00
169_Y	228_L	0.505	1.00
156_M	164_V	0.505	1.00
171_N	200_L	0.503	1.00
168_D	180_H	0.503	1.00
255_G	281_S	0.503	1.00
210_D	213_D	0.502	1.00
85_T	88_V	0.502	1.00
88_V	91_D	0.501	1.00
303_I	318_K	0.500	1.00

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
1a0pA	1	0.7853	100	0.219	Contact Map
2a3vA	3	0.8324	100	0.235	Contact Map
1z1bA	3	0.8382	100	0.251	Contact Map
1z19A	3	0.8265	100	0.254	Contact Map
1xo0A	3	0.8706	100	0.275	Contact Map
4a8eA	2	0.7676	100	0.286	Contact Map
3nkhA	2	0.5853	100	0.418	Contact Map
1ae9A	4	0.5029	100	0.499	Contact Map
1aihA	2	0.4912	99.9	0.534	Contact Map
4e0gA	2	0.8118	99.9	0.573	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.0097 seconds.