Q9HQU9 - HALSA - GREMLIN Contacts

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Q9HQU9 - Bacterio-opsin activator-like protein

UniProt:	Q9HQU9	Sequences: MRGADGRVTDADYRELRGATETPREAVVVGLAGEVGLTSAEIPRVRPCDVAPHDHDGVTHYFLAVPGADGGSDRDAYLPPAVERDIRRRADAAGLADDDPLVDVSARRVQTLVNAVAGRTDTAGLDGVAAQDLRSFFARRLLTGAGVDPRVVAAVGGWSRLASLDQYAAVDAVDRDAIARAFDGTTRAPTDRSEQRAHDRVDEAHSAVLAAGDALSDASTRGAVETAVCEALAASDAYEMAWLARPTTRDDVTVAATAGGDRAIRDDASAAPGATLVQAALDDGTGLFTPAASAAPAVAALREHAAAAGVQAMGVVPVAGPEAAHGVLAVGASTARFSQRERTLITDLGRRVGRAVALAEQRHRLLTDTVLEVAFEVRAGSVFARAAVEQGCDLSLEGVVPGDRQTLVFFVRVAGAPADGVRDWLHDHDGVVSVRVVRDQGGEAVLAVGVAPGADLAMAVVSHGGTIRDLSAGPGGERVVAGVAPETDVRALLDALATAFPGVSLAAKRERARGDETGQRDGASLHDALTDKQAAVLRAAFHAGYFEWPRESTAEDLAADMGVTAPTLHNHLRRAQQKLLATVIDSDGGCDPDTPWPDTRQ	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	601 (495)
Sequences:	358 (326)
Seq/√Len:	14.7

HALSA - Q9HQU9

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
91_D	182_F	7.561	1.00
115_A	154_A	4.785	1.00
191_D	195_Q	4.221	1.00
119_R	154_A	4.154	1.00
460_V	465_G	4.077	1.00
132_D	150_R	3.824	1.00
192_R	195_Q	3.807	1.00
390_Q	394_L	3.609	0.99
162_A	182_F	3.426	0.99
94_G	179_A	3.314	0.99
382_V	387_A	3.243	0.99
91_D	162_A	3.167	0.98
389_E	427_D	2.956	0.97
122_T	129_A	2.853	0.97
122_T	126_D	2.676	0.95
318_V	353_G	2.600	0.95
92_A	181_A	2.536	0.94
94_G	109_V	2.522	0.94
115_A	119_R	2.473	0.93
457_A	461_V	2.473	0.93
393_D	421_V	2.460	0.93
121_D	126_D	2.444	0.92
553_T	566_P	2.423	0.92
463_H	481_A	2.372	0.91
115_A	159_S	2.283	0.90
540_A	549_P	2.175	0.87
392_C	421_V	2.135	0.86
529_L	533_Q	2.127	0.86
109_V	181_A	2.116	0.86
129_A	150_R	2.111	0.85
545_Y	554_A	2.071	0.84
124_G	129_A	2.065	0.84
384_A	393_D	2.063	0.84
243_L	318_V	2.046	0.83
554_A	568_L	1.995	0.82
90_A	167_Y	1.993	0.82
199_D	474_P	1.986	0.82
387_A	422_R	1.986	0.82
422_R	436_V	1.963	0.81
74_R	78_L	1.941	0.80
388_V	452_P	1.933	0.80
93_A	108_R	1.910	0.79
421_V	435_R	1.902	0.79
529_L	532_K	1.902	0.79
387_A	392_C	1.899	0.78
275_T	278_Q	1.870	0.77
524_S	529_L	1.850	0.77
526_H	541_F	1.841	0.76
228_V	327_V	1.830	0.76
393_D	425_L	1.830	0.76
167_Y	177_A	1.800	0.75
92_A	109_V	1.794	0.74
129_A	132_D	1.780	0.74
106_A	109_V	1.779	0.74
106_A	149_P	1.761	0.73
150_R	179_A	1.756	0.73
472_A	475_G	1.753	0.73
75_D	79_P	1.725	0.71
425_L	437_V	1.712	0.71
353_G	362_R	1.709	0.71
526_H	529_L	1.697	0.70
78_L	83_E	1.696	0.70
387_A	391_G	1.692	0.70
529_L	541_F	1.688	0.70
393_D	562_G	1.688	0.70
92_A	106_A	1.686	0.69
469_D	474_P	1.684	0.69
216_S	224_V	1.673	0.69
332_A	337_F	1.644	0.67
431_V	435_R	1.635	0.67
122_T	127_G	1.628	0.67
173_V	184_G	1.610	0.66
358_L	361_Q	1.602	0.65
92_A	179_A	1.594	0.65
392_C	435_R	1.592	0.65
93_A	106_A	1.586	0.65
228_V	352_V	1.582	0.64
109_V	179_A	1.580	0.64
452_P	455_D	1.579	0.64
456_L	460_V	1.568	0.64
384_A	391_G	1.558	0.63
89_R	93_A	1.556	0.63
102_V	179_A	1.554	0.63
150_R	161_L	1.551	0.63
233_A	258_A	1.538	0.62
240_M	337_F	1.530	0.62
380_G	391_G	1.527	0.62
97_D	101_L	1.518	0.61
380_G	393_D	1.517	0.61
387_A	430_G	1.516	0.61
96_A	179_A	1.508	0.60
387_A	421_V	1.504	0.60
109_V	150_R	1.493	0.60
428_H	436_V	1.491	0.60
79_P	83_E	1.487	0.59
386_A	435_R	1.477	0.59
490_R	507_A	1.475	0.59
565_A	569_H	1.466	0.58
524_S	534_A	1.461	0.58
533_Q	537_L	1.457	0.58
89_R	92_A	1.455	0.58
386_A	421_V	1.447	0.57
536_V	540_A	1.430	0.56
382_V	422_R	1.429	0.56
94_G	102_V	1.424	0.56
130_A	139_R	1.417	0.56
455_D	476_G	1.410	0.55
456_L	479_V	1.405	0.55
128_V	131_Q	1.404	0.55
536_V	561_M	1.400	0.55
381_S	446_L	1.390	0.54
204_A	208_V	1.389	0.54
458_M	462_S	1.379	0.53
529_L	540_A	1.378	0.53
548_W	561_M	1.375	0.53
94_G	106_A	1.375	0.53
202_D	205_H	1.371	0.53
543_A	557_L	1.371	0.53
121_D	124_G	1.366	0.53
129_A	165_D	1.358	0.52
153_A	157_G	1.358	0.52
215_L	347_D	1.356	0.52
460_V	463_H	1.349	0.52
549_P	558_A	1.346	0.52
469_D	476_G	1.338	0.51
425_L	430_G	1.334	0.51
358_L	362_R	1.333	0.51
327_V	330_V	1.332	0.51
524_S	528_A	1.332	0.51
381_S	435_R	1.330	0.51
532_K	541_F	1.326	0.51
430_G	437_V	1.321	0.50
525_L	540_A	1.313	0.50
467_I	470_L	1.310	0.50
383_F	391_G	1.307	0.50
375_F	493_L	1.304	0.49
222_G	250_D	1.302	0.49
534_A	541_F	1.301	0.49
468_R	480_V	1.299	0.49
417_P	425_L	1.295	0.49
391_G	427_D	1.294	0.49
161_L	181_A	1.284	0.48
529_L	548_W	1.284	0.48
526_H	536_V	1.280	0.48
523_A	541_F	1.276	0.48
523_A	528_A	1.275	0.48
119_R	156_G	1.269	0.47
387_A	393_D	1.269	0.47
386_A	527_D	1.259	0.47
145_A	165_D	1.258	0.47
280_A	287_L	1.258	0.47
380_G	389_E	1.253	0.47
472_A	477_E	1.253	0.47
523_A	526_H	1.251	0.46
456_L	462_S	1.245	0.46
381_S	421_V	1.234	0.45
395_S	425_L	1.232	0.45
312_A	329_A	1.231	0.45
569_H	572_L	1.229	0.45
106_A	117_A	1.225	0.45
393_D	430_G	1.225	0.45
170_V	174_D	1.220	0.45
388_V	391_G	1.206	0.44
422_R	435_R	1.205	0.44
109_V	151_V	1.204	0.44
281_L	312_A	1.204	0.44
382_V	389_E	1.202	0.44
380_G	437_V	1.200	0.44
524_S	541_F	1.199	0.44
493_L	496_L	1.196	0.43
430_G	433_S	1.195	0.43
112_L	182_F	1.193	0.43
74_R	79_P	1.190	0.43
426_H	435_R	1.181	0.43
105_S	281_L	1.179	0.42
538_R	542_H	1.179	0.42
287_L	312_A	1.167	0.42
545_Y	551_E	1.166	0.42
232_L	238_Y	1.164	0.42
100_P	182_F	1.164	0.42
104_V	129_A	1.161	0.41
393_D	479_V	1.157	0.41
471_S	474_P	1.155	0.41
527_D	537_L	1.151	0.41
74_R	77_Y	1.147	0.41
391_G	430_G	1.141	0.40
418_A	421_V	1.141	0.40
194_E	198_H	1.139	0.40
373_V	390_Q	1.131	0.40
389_E	392_C	1.127	0.40
403_D	562_G	1.126	0.40
149_P	159_S	1.125	0.40
129_A	152_V	1.124	0.40
130_A	159_S	1.120	0.39
422_R	448_V	1.119	0.39
570_N	574_R	1.118	0.39
529_L	537_L	1.117	0.39
373_V	463_H	1.115	0.39
149_P	152_V	1.113	0.39
89_R	164_L	1.112	0.39
382_V	391_G	1.110	0.39
302_R	305_A	1.108	0.39
92_A	128_V	1.108	0.39
393_D	435_R	1.108	0.39
241_A	355_A	1.107	0.39
386_A	392_C	1.107	0.39
109_V	112_L	1.107	0.39
109_V	160_R	1.105	0.38
151_V	179_A	1.105	0.38
221_R	244_A	1.103	0.38
153_A	161_L	1.100	0.38
281_L	327_V	1.095	0.38
159_S	177_A	1.092	0.38
314_G	345_I	1.088	0.38
460_V	471_S	1.085	0.37
521_D	526_H	1.084	0.37
421_V	426_H	1.083	0.37
255_A	258_A	1.082	0.37
254_V	257_T	1.080	0.37
432_V	435_R	1.079	0.37
459_A	462_S	1.077	0.37
147_V	162_A	1.073	0.37
523_A	529_L	1.071	0.37
148_D	195_Q	1.070	0.37
129_A	151_V	1.067	0.37
122_T	165_D	1.067	0.37
388_V	393_D	1.066	0.36
538_R	541_F	1.065	0.36
426_H	433_S	1.065	0.36
389_E	393_D	1.064	0.36
539_A	543_A	1.064	0.36
560_D	566_P	1.062	0.36
429_D	471_S	1.058	0.36
355_A	359_A	1.056	0.36
567_T	571_H	1.050	0.36
394_L	483_V	1.050	0.36
163_S	181_A	1.048	0.36
543_A	548_W	1.046	0.35
452_P	471_S	1.046	0.35
548_W	569_H	1.044	0.35
238_Y	337_F	1.044	0.35
388_V	471_S	1.043	0.35
425_L	489_V	1.042	0.35
115_A	177_A	1.039	0.35
340_R	545_Y	1.038	0.35
102_V	106_A	1.037	0.35
416_A	431_V	1.037	0.35
109_V	113_V	1.032	0.35
376_E	476_G	1.024	0.34
76_A	80_P	1.023	0.34
229_C	241_A	1.016	0.34
526_H	540_A	1.016	0.34
418_A	422_R	1.015	0.34
386_A	422_R	1.014	0.34
534_A	537_L	1.011	0.34
384_A	395_S	1.011	0.34
325_H	337_F	1.009	0.34
529_L	538_R	1.008	0.34
384_A	458_M	1.008	0.34
151_V	165_D	1.004	0.33
320_G	325_H	1.004	0.33
551_E	555_E	1.002	0.33
101_L	176_D	1.001	0.33
289_T	330_V	0.991	0.33
384_A	437_V	0.990	0.33
322_E	517_T	0.989	0.33
448_V	481_A	0.989	0.33
434_V	455_D	0.988	0.33
124_G	161_L	0.988	0.33
426_H	446_L	0.988	0.33
121_D	129_A	0.987	0.33
128_V	154_A	0.986	0.32
401_P	407_L	0.984	0.32
391_G	435_R	0.983	0.32
114_N	156_G	0.982	0.32
195_Q	198_H	0.981	0.32
525_L	541_F	0.977	0.32
152_V	161_L	0.975	0.32
465_G	471_S	0.974	0.32
521_D	525_L	0.970	0.32
397_E	430_G	0.969	0.32
448_V	562_G	0.968	0.32
376_E	417_P	0.967	0.32
421_V	431_V	0.960	0.31
455_D	469_D	0.959	0.31
198_H	341_E	0.957	0.31
380_G	384_A	0.954	0.31
534_A	538_R	0.953	0.31
124_G	159_S	0.949	0.31
319_A	324_A	0.947	0.31
431_V	437_V	0.947	0.31
387_A	396_L	0.947	0.31
474_P	479_V	0.946	0.31
282_D	321_P	0.944	0.30
481_A	484_A	0.943	0.30
362_R	365_L	0.933	0.30
393_D	427_D	0.933	0.30
129_A	161_L	0.932	0.30
421_V	428_H	0.927	0.30
102_V	109_V	0.923	0.29
452_P	483_V	0.920	0.29
92_A	161_L	0.918	0.29
545_Y	549_P	0.918	0.29
525_L	570_N	0.916	0.29
460_V	469_D	0.913	0.29
86_I	104_V	0.907	0.29
89_R	180_R	0.907	0.29
421_V	433_S	0.907	0.29
82_V	318_V	0.900	0.28
422_R	426_H	0.900	0.28
452_P	476_G	0.900	0.28
198_H	202_D	0.899	0.28
291_A	328_L	0.899	0.28
548_W	555_E	0.897	0.28
229_C	329_A	0.896	0.28
146_G	162_A	0.894	0.28
448_V	478_R	0.893	0.28
391_G	426_H	0.890	0.28
106_A	150_R	0.889	0.28
315_V	319_A	0.889	0.28
252_V	258_A	0.888	0.28
168_A	173_V	0.887	0.28
430_G	471_S	0.886	0.28
220_T	351_R	0.885	0.28
149_P	163_S	0.884	0.28
376_E	471_S	0.883	0.28
152_V	157_G	0.882	0.28
349_G	353_G	0.881	0.28
85_D	121_D	0.880	0.28
426_H	477_E	0.877	0.27
530_T	533_Q	0.877	0.27
382_V	425_L	0.875	0.27
109_V	163_S	0.874	0.27
221_R	356_V	0.872	0.27
541_F	548_W	0.872	0.27
376_E	395_S	0.871	0.27
184_G	224_V	0.870	0.27
305_A	310_V	0.868	0.27
208_V	214_A	0.867	0.27
523_A	527_D	0.865	0.27
384_A	428_H	0.862	0.27
452_P	456_L	0.861	0.27
255_A	266_D	0.858	0.27
395_S	489_V	0.856	0.26
454_A	462_S	0.855	0.26
427_D	452_P	0.849	0.26
207_A	353_G	0.847	0.26
533_Q	541_F	0.846	0.26
387_A	417_P	0.845	0.26
376_E	426_H	0.844	0.26
385_R	392_C	0.844	0.26
83_E	92_A	0.844	0.26
194_E	202_D	0.842	0.26
91_D	167_Y	0.841	0.26
529_L	543_A	0.841	0.26
130_A	179_A	0.839	0.26
224_V	327_V	0.839	0.26
113_V	181_A	0.833	0.25
384_A	392_C	0.830	0.25
422_R	479_V	0.827	0.25
461_V	466_T	0.827	0.25
97_D	315_V	0.827	0.25
238_Y	341_E	0.825	0.25
167_Y	211_A	0.824	0.25
384_A	421_V	0.824	0.25
554_A	570_N	0.822	0.25
298_V	313_M	0.822	0.25
215_L	321_P	0.821	0.25
106_A	181_A	0.820	0.25
382_V	434_V	0.819	0.25
178_I	235_S	0.817	0.25
373_V	376_E	0.815	0.25
493_L	503_V	0.812	0.25
529_L	536_V	0.810	0.25
216_S	351_R	0.809	0.24
219_S	362_R	0.809	0.24
383_F	392_C	0.806	0.24
142_L	192_R	0.806	0.24
530_T	540_A	0.805	0.24
267_D	474_P	0.805	0.24
312_A	337_F	0.804	0.24
316_V	492_L	0.803	0.24
391_G	436_V	0.802	0.24
456_L	469_D	0.799	0.24
522_G	552_S	0.798	0.24
122_T	159_S	0.797	0.24
381_S	426_H	0.797	0.24
95_L	103_D	0.793	0.24
85_D	90_A	0.793	0.24
384_A	427_D	0.791	0.24
321_P	329_A	0.790	0.24
94_G	181_A	0.789	0.24
159_S	165_D	0.788	0.24
386_A	395_S	0.787	0.24
160_R	179_A	0.786	0.24
394_L	424_W	0.786	0.24
95_L	176_D	0.786	0.24
462_S	465_G	0.785	0.24
185_T	231_A	0.785	0.24
111_T	318_V	0.784	0.23
149_P	181_A	0.781	0.23
205_H	208_V	0.780	0.23
390_Q	459_A	0.779	0.23
201_V	205_H	0.777	0.23
160_R	374_A	0.776	0.23
95_L	179_A	0.775	0.23
373_V	381_S	0.772	0.23
420_G	434_V	0.772	0.23
428_H	433_S	0.771	0.23
124_G	133_L	0.771	0.23
380_G	395_S	0.770	0.23
183_D	243_L	0.769	0.23
152_V	160_R	0.768	0.23
167_Y	182_F	0.768	0.23
151_V	181_A	0.767	0.23
217_D	557_L	0.767	0.23
376_E	383_F	0.767	0.23
394_L	432_V	0.767	0.23
520_R	523_A	0.767	0.23
380_G	392_C	0.766	0.23
479_V	574_R	0.765	0.23
115_A	156_G	0.764	0.23
162_A	167_Y	0.764	0.23
389_E	417_P	0.764	0.23
94_G	149_P	0.762	0.23
96_A	100_P	0.761	0.23
553_T	560_D	0.761	0.23
196_R	262_R	0.760	0.23
386_A	428_H	0.757	0.22
226_T	460_V	0.756	0.22
123_A	129_A	0.755	0.22
429_D	479_V	0.754	0.22
426_H	448_V	0.753	0.22
236_D	241_A	0.752	0.22
197_A	289_T	0.751	0.22
222_G	402_G	0.751	0.22
361_Q	364_R	0.749	0.22
192_R	502_G	0.749	0.22
185_T	237_A	0.749	0.22
133_L	165_D	0.748	0.22
246_P	467_I	0.748	0.22
526_H	542_H	0.748	0.22
566_P	569_H	0.748	0.22
114_N	154_A	0.747	0.22
427_D	457_A	0.747	0.22
459_A	463_H	0.747	0.22
161_L	177_A	0.746	0.22
273_G	475_G	0.746	0.22
116_V	174_D	0.745	0.22
554_A	565_A	0.745	0.22
153_A	159_S	0.744	0.22
365_L	368_D	0.744	0.22
134_R	139_R	0.739	0.22
160_R	192_R	0.739	0.22
422_R	433_S	0.738	0.22
378_R	446_L	0.738	0.22
202_D	206_S	0.736	0.22
457_A	460_V	0.736	0.22
179_A	183_D	0.736	0.22
184_G	192_R	0.734	0.22
132_D	139_R	0.733	0.22
386_A	407_L	0.732	0.21
327_V	467_I	0.726	0.21
518_G	527_D	0.723	0.21
392_C	463_H	0.723	0.21
250_D	263_A	0.722	0.21
129_A	159_S	0.721	0.21
156_G	544_G	0.721	0.21
383_F	387_A	0.720	0.21
391_G	395_S	0.719	0.21
427_D	471_S	0.719	0.21
217_D	318_V	0.718	0.21
89_R	161_L	0.718	0.21
105_S	152_V	0.713	0.21
383_F	432_V	0.712	0.21
382_V	452_P	0.711	0.21
461_V	468_R	0.707	0.21
382_V	390_Q	0.706	0.21
527_D	534_A	0.706	0.21
429_D	435_R	0.704	0.20
432_V	437_V	0.703	0.20
381_S	503_V	0.702	0.20
381_S	469_D	0.701	0.20
95_L	104_V	0.701	0.20
545_Y	556_D	0.698	0.20
392_C	395_S	0.697	0.20
229_C	352_V	0.696	0.20
299_A	310_V	0.696	0.20
443_E	451_A	0.695	0.20
446_L	467_I	0.693	0.20
186_T	224_V	0.691	0.20
168_A	419_D	0.691	0.20
426_H	436_V	0.690	0.20
115_A	166_Q	0.689	0.20
237_A	562_G	0.689	0.20
388_V	485_P	0.686	0.20
544_G	552_S	0.686	0.20
168_A	216_S	0.686	0.20
184_G	195_Q	0.686	0.20
223_A	562_G	0.685	0.20
180_R	345_I	0.683	0.20
396_L	400_V	0.683	0.20
371_L	374_A	0.682	0.20
192_R	196_R	0.682	0.20
390_Q	431_V	0.680	0.20
392_C	425_L	0.678	0.20
394_L	420_G	0.676	0.19
527_D	541_F	0.676	0.19
522_G	548_W	0.675	0.19
128_V	133_L	0.675	0.19
122_T	136_F	0.673	0.19
431_V	434_V	0.672	0.19
292_A	322_E	0.671	0.19
553_T	570_N	0.668	0.19
209_L	212_G	0.667	0.19
124_G	151_V	0.665	0.19
382_V	448_V	0.665	0.19
105_S	109_V	0.665	0.19
391_G	557_L	0.665	0.19
427_D	432_V	0.665	0.19
103_D	464_G	0.664	0.19
301_L	310_V	0.664	0.19
358_L	365_L	0.662	0.19
313_M	348_L	0.662	0.19
96_A	165_D	0.662	0.19
254_V	258_A	0.661	0.19
537_L	542_H	0.661	0.19
411_V	417_P	0.660	0.19
393_D	437_V	0.657	0.19
463_H	489_V	0.657	0.19
411_V	480_V	0.657	0.19
224_V	341_E	0.657	0.19
82_V	104_V	0.656	0.19
136_F	145_A	0.655	0.19
166_Q	178_I	0.653	0.19
508_K	554_A	0.652	0.19
380_G	383_F	0.652	0.19
194_E	207_A	0.652	0.19
96_A	102_V	0.651	0.19
529_L	542_H	0.651	0.19
315_V	327_V	0.651	0.19
248_T	498_T	0.650	0.19
337_F	342_R	0.650	0.19
219_S	557_L	0.649	0.19
86_I	178_I	0.649	0.19
420_G	503_V	0.648	0.18
396_L	467_I	0.648	0.18
91_D	198_H	0.648	0.18
430_G	435_R	0.647	0.18
124_G	181_A	0.647	0.18
150_R	153_A	0.647	0.18
532_K	554_A	0.646	0.18
538_R	543_A	0.646	0.18
145_A	149_P	0.645	0.18
399_V	467_I	0.645	0.18
376_E	382_V	0.644	0.18
132_D	149_P	0.644	0.18
425_L	435_R	0.643	0.18
148_D	191_D	0.642	0.18
387_A	427_D	0.641	0.18
421_V	463_H	0.640	0.18
382_V	511_R	0.639	0.18
380_G	388_V	0.638	0.18
389_E	422_R	0.637	0.18
390_Q	427_D	0.636	0.18
535_A	539_A	0.634	0.18
76_A	79_P	0.632	0.18
532_K	540_A	0.632	0.18
128_V	153_A	0.632	0.18
114_N	129_A	0.631	0.18
124_G	165_D	0.630	0.18
387_A	437_V	0.629	0.18
81_A	474_P	0.628	0.18
522_G	549_P	0.628	0.18
186_T	481_A	0.628	0.18
527_D	535_A	0.627	0.18
456_L	471_S	0.627	0.18
532_K	536_V	0.627	0.18
347_D	351_R	0.626	0.18
284_G	319_A	0.625	0.18
113_V	151_V	0.624	0.18
132_D	137_F	0.623	0.18
362_R	369_T	0.623	0.18
242_W	331_G	0.622	0.18
561_M	569_H	0.621	0.18
388_V	429_D	0.620	0.18
85_D	95_L	0.620	0.18
102_V	151_V	0.618	0.18
137_F	200_R	0.618	0.18
84_R	105_S	0.616	0.17
389_E	452_P	0.616	0.17
525_L	529_L	0.615	0.17
392_C	462_S	0.614	0.17
104_V	109_V	0.614	0.17
412_R	486_E	0.614	0.17
406_T	502_G	0.611	0.17
520_R	548_W	0.611	0.17
159_S	164_L	0.611	0.17
524_S	562_G	0.610	0.17
233_A	238_Y	0.609	0.17
204_A	207_A	0.608	0.17
103_D	559_A	0.608	0.17
428_H	435_R	0.607	0.17
208_V	319_A	0.607	0.17
538_R	553_T	0.606	0.17
433_S	452_P	0.606	0.17
105_S	165_D	0.605	0.17
259_G	337_F	0.605	0.17
102_V	181_A	0.604	0.17
332_A	341_E	0.603	0.17
150_R	211_A	0.603	0.17
421_V	430_G	0.603	0.17
551_E	565_A	0.602	0.17
353_G	358_L	0.602	0.17
383_F	390_Q	0.600	0.17
103_D	161_L	0.598	0.17
522_G	529_L	0.598	0.17
385_R	389_E	0.598	0.17
548_W	570_N	0.598	0.17
537_L	541_F	0.597	0.17
129_A	149_P	0.596	0.17
186_T	191_D	0.595	0.17
146_G	164_L	0.593	0.17
393_D	436_V	0.593	0.17
239_E	296_P	0.593	0.17
273_G	371_L	0.592	0.17
155_V	160_R	0.592	0.17
389_E	489_V	0.590	0.17
102_V	107_R	0.587	0.17
229_C	348_L	0.586	0.17
185_T	278_Q	0.586	0.17
86_I	93_A	0.585	0.16
391_G	422_R	0.584	0.16
100_P	324_A	0.584	0.16
528_A	543_A	0.583	0.16
226_T	492_L	0.581	0.16
232_L	337_F	0.580	0.16
429_D	434_V	0.580	0.16
533_Q	540_A	0.576	0.16
383_F	429_D	0.575	0.16
394_L	431_V	0.575	0.16
448_V	480_V	0.575	0.16
549_P	561_M	0.573	0.16
427_D	455_D	0.571	0.16
238_Y	332_A	0.571	0.16
149_P	160_R	0.571	0.16
233_A	365_L	0.570	0.16
507_A	545_Y	0.568	0.16
320_G	326_G	0.568	0.16
287_L	296_P	0.567	0.16
387_A	436_V	0.567	0.16
437_V	479_V	0.567	0.16
257_T	333_S	0.566	0.16
272_P	278_Q	0.565	0.16
104_V	160_R	0.565	0.16
384_A	456_L	0.564	0.16
92_A	121_D	0.564	0.16
306_A	331_G	0.563	0.16
129_A	177_A	0.562	0.16
252_V	327_V	0.561	0.16
476_G	479_V	0.560	0.16
331_G	337_F	0.560	0.16
380_G	560_D	0.560	0.16
162_A	191_D	0.560	0.16
565_A	570_N	0.560	0.16
532_K	537_L	0.559	0.16
184_G	448_V	0.558	0.16
220_T	381_S	0.557	0.16
382_V	455_D	0.555	0.16
242_W	329_A	0.555	0.16
497_A	502_G	0.553	0.16
133_L	152_V	0.553	0.16
344_L	404_R	0.551	0.15
380_G	421_V	0.551	0.15
216_S	404_R	0.551	0.15
536_V	545_Y	0.550	0.15
241_A	325_H	0.547	0.15
148_D	173_V	0.547	0.15
382_V	485_P	0.546	0.15
471_S	476_G	0.546	0.15
462_S	471_S	0.546	0.15
431_V	476_G	0.546	0.15
151_V	182_F	0.542	0.15
456_L	465_G	0.542	0.15
384_A	433_S	0.538	0.15
219_S	361_Q	0.537	0.15
222_G	467_I	0.536	0.15
386_A	390_Q	0.536	0.15
395_S	465_G	0.536	0.15
224_V	484_A	0.535	0.15
387_A	395_S	0.535	0.15
149_P	153_A	0.534	0.15
382_V	469_D	0.532	0.15
421_V	427_D	0.531	0.15
281_L	331_G	0.531	0.15
318_V	361_Q	0.531	0.15
88_R	167_Y	0.530	0.15
145_A	164_L	0.529	0.15
422_R	430_G	0.529	0.15
175_R	182_F	0.529	0.15
244_A	331_G	0.528	0.15
160_R	185_T	0.528	0.15
259_G	263_A	0.528	0.15
428_H	474_P	0.528	0.15
534_A	540_A	0.527	0.15
530_T	544_G	0.527	0.15
537_L	540_A	0.527	0.15
387_A	479_V	0.526	0.15
84_R	161_L	0.526	0.15
406_T	456_L	0.525	0.15
199_D	217_D	0.525	0.15
252_V	297_A	0.524	0.15
174_D	250_D	0.524	0.15
391_G	555_E	0.522	0.15
203_E	319_A	0.522	0.15
91_D	160_R	0.522	0.15
548_W	565_A	0.522	0.15
138_A	467_I	0.521	0.15
229_C	365_L	0.520	0.15
525_L	560_D	0.517	0.15
86_I	106_A	0.517	0.15
391_G	458_M	0.516	0.14
478_R	512_A	0.512	0.14
361_Q	365_L	0.511	0.14
152_V	163_S	0.510	0.14
280_A	331_G	0.510	0.14
396_L	470_L	0.509	0.14
105_S	130_A	0.508	0.14
124_G	132_D	0.508	0.14
174_D	279_A	0.507	0.14
93_A	105_S	0.507	0.14
391_G	433_S	0.506	0.14
186_T	348_L	0.506	0.14
390_Q	393_D	0.506	0.14
220_T	241_A	0.505	0.14
428_H	528_A	0.505	0.14
79_P	86_I	0.504	0.14
96_A	181_A	0.504	0.14
130_A	150_R	0.503	0.14
403_D	407_L	0.500	0.14
77_Y	80_P	0.500	0.14
385_R	435_R	0.500	0.14

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
4e04A	2	0.4592	100	0.789	Contact Map
2oolA	2	0.4542	100	0.817	Contact Map
4r70A	4	0.7121	100	0.818	Contact Map
4gczA	2	0.426	100	0.818	Contact Map
4s21A	2	0.6772	100	0.822	Contact Map
3nhqA	2	0.7105	100	0.828	Contact Map
3zq5A	2	0.7504	99.9	0.829	Contact Map
4cqhA	1	0.4559	99.9	0.829	Contact Map
4i5sA	2	0.4725	99.9	0.834	Contact Map
3a0rA	2	0.381	99.9	0.837	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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