IMDH - HALSA - GREMLIN Contacts

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IMDH - Inosine-5'-monophosphate dehydrogenase

UniProt:	Q9HQU4	Sequences: MANDSSTDGRFSEKLRVPEALTFDDVLLRPAESRVEPDDADVATRVSTNVELEVPVLSAAMDTVTESRLAIAMAREGGLGVLHQNMDTDRVVAEVERVKRADELVIDRENVVTAAPEQTVEAVDEMMDRSDVSGAPVVDDDDTVRGIISATDIRPYLEVGESDAVREAMTDEVITAPEDITARDALELMYEHKIERVPIVNDEQHLVGLVTMQGILERREHGSAARDQNGRLRVGVAVGPFDTERATAVDEAGADVLFIDCAHAHNLNVIDSAREIKASVDADVVVGNVGTREAAEAVVDFADGIKVGIGPGSICTTRVVTGSGMPQITAVSQVADVAAPAGVPVIADGGIRYSGDAAKAIAAGADAVMLGSYFAGTDEAPGRVITMNGKKYKQYRGMGSVGAMQSGGSDRYLKDDDEDEEYVPEGVEAATPYKGSLASELHQLVGGIQSGMGYVGAESIPAFKADAEFVRVSAAGQTEGHPHDVMITDEAPNYSPQGE	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	499 (469)
Sequences:	2845 (1085)
Seq/√Len:	50.1

ECOLI - IMDH GUAC
BACSU - IMDH GUAC
HALSA - IMDH

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
81_V	235_G	6.458	1.00
49_N	283_D	4.656	1.00
88_T	248_A	4.255	1.00
459_S	462_A	4.091	1.00
201_N	205_H	4.008	1.00
19_E	471_R	3.714	1.00
114_A	137_V	3.587	1.00
358_A	451_G	3.564	1.00
225_A	233_R	3.239	1.00
337_V	340_P	3.233	1.00
296_E	300_D	3.233	1.00
366_D	464_K	3.147	1.00
65_T	80_G	3.114	1.00
43_A	51_E	3.042	1.00
45_R	51_E	3.018	1.00
267_L	271_D	2.879	1.00
361_I	448_I	2.819	1.00
176_A	199_I	2.797	1.00
34_R	267_L	2.783	1.00
247_T	251_E	2.678	1.00
296_E	337_V	2.670	1.00
81_V	256_V	2.657	1.00
462_A	466_D	2.653	1.00
277_K	284_V	2.628	1.00
289_V	295_A	2.607	1.00
250_D	282_A	2.586	1.00
246_A	276_I	2.527	1.00
32_E	297_A	2.522	1.00
32_E	267_L	2.467	1.00
293_E	468_E	2.445	1.00
352_R	477_Q	2.444	1.00
458_E	462_A	2.404	1.00
56_V	441_L	2.400	1.00
460_I	464_K	2.372	1.00
289_V	294_A	2.338	1.00
295_A	334_V	2.337	1.00
87_D	90_R	2.327	1.00
295_A	299_V	2.320	1.00
118_Q	122_A	2.309	1.00
299_V	338_A	2.279	1.00
94_E	97_R	2.278	1.00
294_A	334_V	2.266	1.00
238_V	246_A	2.265	1.00
235_G	256_V	2.252	1.00
42_V	445_V	2.241	1.00
289_V	334_V	2.235	1.00
163_D	167_E	2.217	1.00
18_P	333_Q	2.197	1.00
370_L	374_F	2.194	1.00
121_E	125_E	2.192	1.00
277_K	303_D	2.190	1.00
181_T	184_D	2.147	1.00
257_L	282_A	2.139	1.00
47_S	283_D	2.127	1.00
46_V	256_V	2.105	1.00
246_A	257_L	2.090	1.00
137_V	165_V	2.035	1.00
461_P	465_A	2.009	1.00
370_L	373_Y	1.993	1.00
69_L	437_L	1.979	1.00
79_L	256_V	1.965	0.99
271_D	274_R	1.949	0.99
45_R	342_G	1.929	0.99
67_S	94_E	1.914	0.99
46_V	285_V	1.909	0.99
358_A	463_F	1.908	0.99
427_V	485_V	1.888	0.99
357_A	368_V	1.885	0.99
461_P	464_K	1.885	0.99
297_A	300_D	1.882	0.99
114_A	165_V	1.881	0.99
114_A	123_V	1.875	0.99
177_P	202_D	1.861	0.99
115_A	118_Q	1.840	0.99
158_E	163_D	1.837	0.99
402_G	428_E	1.829	0.99
338_A	345_V	1.815	0.99
121_E	162_S	1.810	0.99
276_I	284_V	1.757	0.99
295_A	345_V	1.750	0.99
95_V	254_A	1.735	0.99
141_D	205_H	1.703	0.98
247_T	280_V	1.702	0.98
123_V	148_I	1.697	0.98
273_A	286_V	1.691	0.98
73_M	441_L	1.679	0.98
117_E	164_A	1.677	0.98
116_P	145_R	1.666	0.98
54_V	445_V	1.665	0.98
261_C	269_V	1.662	0.98
247_T	279_S	1.651	0.98
187_E	191_E	1.645	0.98
114_A	118_Q	1.639	0.98
164_A	167_E	1.637	0.98
259_I	273_A	1.635	0.98
373_Y	444_L	1.600	0.98
361_I	460_I	1.595	0.98
256_V	285_V	1.592	0.98
56_V	370_L	1.586	0.98
292_R	337_V	1.572	0.97
262_A	454_Y	1.553	0.97
307_V	345_V	1.543	0.97
57_L	367_A	1.535	0.97
296_E	340_P	1.526	0.97
299_V	343_V	1.524	0.97
47_S	304_G	1.513	0.97
125_E	129_R	1.507	0.97
81_V	258_F	1.497	0.97
177_P	180_I	1.489	0.96
178_E	207_V	1.486	0.96
56_V	374_F	1.483	0.96
90_R	94_E	1.460	0.96
284_V	302_A	1.459	0.96
295_A	338_A	1.458	0.96
43_A	53_E	1.458	0.96
46_V	235_G	1.448	0.96
374_F	437_L	1.440	0.96
422_Y	450_S	1.437	0.96
339_A	464_K	1.433	0.96
270_I	274_R	1.432	0.96
451_G	463_F	1.423	0.95
143_T	205_H	1.412	0.95
300_D	341_A	1.404	0.95
117_E	166_R	1.387	0.95
176_A	180_I	1.380	0.95
457_A	467_A	1.372	0.94
123_V	127_M	1.368	0.94
58_S	65_T	1.363	0.94
184_D	187_E	1.363	0.94
48_T	344_P	1.362	0.94
290_G	325_M	1.349	0.94
292_R	336_D	1.346	0.94
148_I	168_A	1.345	0.94
296_E	341_A	1.340	0.94
246_A	280_V	1.337	0.94
46_V	367_A	1.335	0.93
332_S	336_D	1.334	0.93
378_D	436_S	1.318	0.93
331_V	347_A	1.306	0.93
299_V	341_A	1.305	0.93
57_L	285_V	1.289	0.92
286_V	302_A	1.280	0.92
34_R	458_E	1.278	0.92
384_V	391_K	1.274	0.92
259_I	286_V	1.268	0.92
95_V	236_V	1.268	0.92
49_N	281_D	1.262	0.91
378_D	433_Y	1.262	0.91
338_A	341_A	1.245	0.91
48_T	303_D	1.236	0.91
304_G	367_A	1.234	0.90
361_I	464_K	1.232	0.90
138_V	141_D	1.232	0.90
254_A	282_A	1.229	0.90
49_N	228_Q	1.217	0.90
84_Q	268_N	1.217	0.90
335_A	345_V	1.215	0.90
361_I	463_F	1.206	0.89
115_A	145_R	1.199	0.89
427_V	491_A	1.193	0.89
344_P	366_D	1.184	0.89
180_I	184_D	1.183	0.88
190_Y	193_K	1.182	0.88
36_E	268_N	1.182	0.88
242_D	272_S	1.177	0.88
319_V	477_Q	1.170	0.88
452_M	460_I	1.169	0.88
457_A	462_A	1.159	0.87
292_R	296_E	1.157	0.87
69_L	374_F	1.153	0.87
42_V	449_Q	1.149	0.87
58_S	73_M	1.146	0.87
112_V	137_V	1.145	0.87
46_V	57_L	1.145	0.87
243_T	275_E	1.143	0.87
132_V	135_A	1.142	0.87
122_A	125_E	1.140	0.87
339_A	465_A	1.136	0.86
41_D	51_E	1.136	0.86
160_G	163_D	1.128	0.86
39_D	458_E	1.127	0.86
58_S	80_G	1.118	0.85
139_D	145_R	1.116	0.85
362_A	467_A	1.112	0.85
463_F	467_A	1.109	0.85
244_E	247_T	1.106	0.85
119_T	164_A	1.103	0.85
295_A	337_V	1.101	0.85
28_L	455_V	1.101	0.85
178_E	202_D	1.099	0.84
46_V	304_G	1.094	0.84
275_E	279_S	1.093	0.84
124_D	161_E	1.089	0.84
299_V	337_V	1.087	0.84
56_V	445_V	1.086	0.84
159_V	187_E	1.085	0.84
363_A	469_F	1.085	0.84
259_I	269_V	1.082	0.84
259_I	276_I	1.078	0.83
274_R	278_A	1.065	0.83
228_Q	233_R	1.055	0.82
44_T	54_V	1.050	0.82
305_I	338_A	1.049	0.82
105_V	199_I	1.042	0.81
139_D	142_D	1.041	0.81
357_A	444_L	1.038	0.81
257_L	261_C	1.035	0.81
20_A	470_V	1.030	0.80
336_D	340_P	1.023	0.80
60_A	306_K	1.023	0.80
67_S	97_R	1.023	0.80
152_D	198_P	1.023	0.80
277_K	302_A	1.018	0.80
299_V	340_P	1.018	0.80
75_R	101_A	1.015	0.79
31_A	468_E	1.014	0.79
23_F	331_V	1.010	0.79
21_L	471_R	1.010	0.79
295_A	305_I	1.007	0.79
304_G	344_P	1.006	0.79
116_P	148_I	1.004	0.79
246_A	282_A	1.003	0.79
482_P	485_V	1.002	0.79
31_A	466_D	0.999	0.78
135_A	165_V	0.994	0.78
366_D	461_P	0.988	0.78
274_R	300_D	0.986	0.77
47_S	256_V	0.985	0.77
189_M	197_V	0.984	0.77
292_R	333_Q	0.983	0.77
200_V	204_Q	0.979	0.77
182_A	186_L	0.978	0.77
368_V	374_F	0.974	0.77
374_F	476_G	0.973	0.76
374_F	441_L	0.972	0.76
319_V	482_P	0.965	0.76
57_L	79_L	0.951	0.75
457_A	466_D	0.951	0.75
21_L	328_I	0.949	0.75
273_A	302_A	0.942	0.74
457_A	482_P	0.941	0.74
177_P	184_D	0.940	0.74
377_T	437_L	0.939	0.74
185_A	197_V	0.939	0.74
185_A	198_P	0.934	0.73
370_L	444_L	0.932	0.73
50_V	233_R	0.931	0.73
289_V	305_I	0.929	0.73
236_V	254_A	0.926	0.73
121_E	161_E	0.923	0.73
216_L	220_E	0.923	0.73
331_V	345_V	0.922	0.72
270_I	297_A	0.921	0.72
302_A	305_I	0.918	0.72
48_T	343_V	0.917	0.72
334_V	337_V	0.913	0.72
119_T	122_A	0.913	0.72
76_E	438_A	0.912	0.72
45_R	48_T	0.911	0.72
120_V	158_E	0.911	0.72
337_V	341_A	0.909	0.71
290_G	309_I	0.908	0.71
116_P	138_V	0.907	0.71
339_A	366_D	0.906	0.71
238_V	257_L	0.905	0.71
139_D	143_T	0.904	0.71
361_I	467_A	0.902	0.71
29_R	33_S	0.900	0.71
84_Q	407_G	0.900	0.71
176_A	188_L	0.897	0.70
338_A	366_D	0.895	0.70
93_A	96_E	0.895	0.70
131_D	150_A	0.894	0.70
246_A	250_D	0.892	0.70
282_A	303_D	0.879	0.69
33_S	263_H	0.878	0.69
31_A	457_A	0.877	0.69
243_T	279_S	0.874	0.68
265_H	297_A	0.874	0.68
116_P	166_R	0.873	0.68
238_V	259_I	0.870	0.68
112_V	132_V	0.870	0.68
90_R	93_A	0.868	0.68
48_T	283_D	0.867	0.68
283_D	304_G	0.866	0.68
114_A	122_A	0.856	0.67
450_S	453_G	0.852	0.66
273_A	284_V	0.848	0.66
202_D	205_H	0.846	0.66
174_I	192_H	0.846	0.66
139_D	205_H	0.844	0.66
118_Q	135_A	0.843	0.66
328_I	467_A	0.843	0.66
26_V	363_A	0.837	0.65
144_V	196_R	0.837	0.65
321_T	480_G	0.836	0.65
472_V	477_Q	0.835	0.65
63_T	66_E	0.830	0.64
273_A	294_A	0.825	0.64
114_A	126_M	0.821	0.64
117_E	139_D	0.820	0.63
270_I	286_V	0.815	0.63
422_Y	442_H	0.814	0.63
56_V	73_M	0.812	0.63
53_E	225_A	0.811	0.63
289_V	345_V	0.809	0.62
457_A	465_A	0.807	0.62
182_A	188_L	0.805	0.62
31_A	455_V	0.804	0.62
436_S	439_S	0.803	0.62
399_G	412_Y	0.802	0.62
271_D	275_E	0.800	0.61
176_A	198_P	0.799	0.61
437_L	441_L	0.799	0.61
40_A	459_S	0.797	0.61
387_M	430_A	0.796	0.61
105_V	113_T	0.792	0.61
120_V	163_D	0.790	0.61
328_I	363_A	0.790	0.61
272_S	275_E	0.789	0.60
257_L	321_T	0.789	0.60
290_G	334_V	0.789	0.60
69_L	73_M	0.788	0.60
122_A	165_V	0.787	0.60
370_L	437_L	0.787	0.60
329_T	332_S	0.784	0.60
334_V	345_V	0.784	0.60
354_S	444_L	0.782	0.60
110_N	206_L	0.782	0.60
124_D	128_D	0.780	0.60
114_A	482_P	0.779	0.59
216_L	352_R	0.776	0.59
81_V	262_A	0.775	0.59
92_V	248_A	0.769	0.58
248_A	251_E	0.766	0.58
75_R	439_S	0.761	0.58
186_L	218_R	0.758	0.57
352_R	407_G	0.758	0.57
385_I	430_A	0.757	0.57
44_T	460_I	0.755	0.57
233_R	256_V	0.754	0.57
79_L	367_A	0.754	0.57
319_V	470_V	0.753	0.57
103_E	106_I	0.750	0.57
186_L	193_K	0.746	0.56
338_A	477_Q	0.746	0.56
29_R	468_E	0.744	0.56
45_R	366_D	0.743	0.56
122_A	135_A	0.741	0.56
187_E	284_V	0.741	0.56
329_T	333_Q	0.740	0.56
69_L	441_L	0.739	0.55
259_I	295_A	0.739	0.55
23_F	309_I	0.738	0.55
158_E	161_E	0.738	0.55
124_D	148_I	0.738	0.55
250_D	280_V	0.737	0.55
240_P	422_Y	0.736	0.55
82_L	95_V	0.735	0.55
178_E	201_N	0.735	0.55
72_A	441_L	0.733	0.55
59_A	306_K	0.731	0.55
92_V	96_E	0.731	0.55
103_E	226_R	0.729	0.54
204_Q	207_V	0.726	0.54
476_G	480_G	0.726	0.54
42_V	448_I	0.726	0.54
334_V	338_A	0.725	0.54
115_A	139_D	0.723	0.54
106_I	182_A	0.718	0.53
29_R	455_V	0.717	0.53
377_T	440_E	0.716	0.53
335_A	342_G	0.716	0.53
250_D	254_A	0.716	0.53
270_I	294_A	0.715	0.53
127_M	197_V	0.715	0.53
127_M	132_V	0.715	0.53
44_T	367_A	0.712	0.53
93_A	129_R	0.712	0.53
455_V	467_A	0.711	0.53
185_A	210_V	0.711	0.53
91_V	254_A	0.710	0.52
127_M	135_A	0.709	0.52
303_D	343_V	0.709	0.52
243_T	246_A	0.708	0.52
182_A	215_I	0.708	0.52
96_E	207_V	0.706	0.52
409_S	416_D	0.706	0.52
100_R	150_A	0.706	0.52
357_A	370_L	0.705	0.52
240_P	272_S	0.700	0.51
385_I	489_D	0.699	0.51
42_V	54_V	0.699	0.51
20_A	329_T	0.699	0.51
240_P	273_A	0.698	0.51
50_V	283_D	0.698	0.51
73_M	374_F	0.696	0.51
29_R	309_I	0.696	0.51
185_A	209_L	0.696	0.51
59_A	433_Y	0.695	0.51
473_S	476_G	0.694	0.51
292_R	335_A	0.694	0.51
176_A	212_M	0.693	0.51
311_P	316_T	0.692	0.51
39_D	68_R	0.692	0.51
87_D	434_K	0.691	0.51
92_V	252_A	0.690	0.50
105_V	112_V	0.690	0.50
124_D	153_I	0.689	0.50
115_A	166_R	0.684	0.50
76_E	221_H	0.680	0.49
115_A	140_D	0.680	0.49
38_D	415_D	0.679	0.49
46_V	52_L	0.678	0.49
420_E	439_S	0.678	0.49
247_T	250_D	0.677	0.49
254_A	257_L	0.677	0.49
118_Q	165_V	0.676	0.49
423_V	450_S	0.676	0.49
394_Q	442_H	0.676	0.49
300_D	340_P	0.676	0.49
429_A	485_V	0.673	0.49
75_R	482_P	0.671	0.48
321_T	478_T	0.670	0.48
107_D	229_N	0.667	0.48
239_G	242_D	0.667	0.48
358_A	361_I	0.666	0.48
385_I	392_Y	0.666	0.48
84_Q	309_I	0.664	0.48
46_V	329_T	0.663	0.48
244_E	248_A	0.663	0.48
259_I	284_V	0.661	0.47
51_E	233_R	0.661	0.47
268_N	271_D	0.661	0.47
261_C	294_A	0.660	0.47
399_G	411_R	0.660	0.47
72_A	437_L	0.659	0.47
261_C	268_N	0.658	0.47
47_S	285_V	0.657	0.47
120_V	168_A	0.651	0.46
73_M	79_L	0.650	0.46
180_I	188_L	0.649	0.46
56_V	294_A	0.649	0.46
246_A	284_V	0.648	0.46
177_P	207_V	0.648	0.46
101_A	221_H	0.648	0.46
334_V	366_D	0.647	0.46
60_A	295_A	0.646	0.46
22_T	328_I	0.645	0.46
319_V	480_G	0.645	0.46
101_A	130_S	0.644	0.46
152_D	169_M	0.644	0.46
241_F	420_E	0.643	0.46
357_A	448_I	0.643	0.46
118_Q	166_R	0.643	0.46
304_G	343_V	0.642	0.45
290_G	396_R	0.640	0.45
47_S	50_V	0.640	0.45
144_V	200_V	0.639	0.45
126_M	135_A	0.639	0.45
100_R	392_Y	0.638	0.45
321_T	472_V	0.637	0.45
46_V	79_L	0.636	0.45
113_T	199_I	0.636	0.45
152_D	170_T	0.635	0.45
29_R	470_V	0.635	0.45
105_V	179_D	0.634	0.45
180_I	185_A	0.633	0.45
93_A	97_R	0.633	0.45
333_Q	336_D	0.631	0.44
153_I	161_E	0.631	0.44
242_D	409_S	0.629	0.44
105_V	385_I	0.629	0.44
106_I	188_L	0.628	0.44
149_S	170_T	0.627	0.44
35_V	40_A	0.626	0.44
134_G	196_R	0.626	0.44
198_P	206_L	0.625	0.44
113_T	135_A	0.624	0.44
23_F	133_S	0.624	0.44
114_A	176_A	0.623	0.44
300_D	337_V	0.623	0.44
71_I	175_T	0.622	0.43
103_E	427_V	0.621	0.43
143_T	203_E	0.620	0.43
155_P	396_R	0.620	0.43
296_E	299_V	0.620	0.43
352_R	390_K	0.619	0.43
110_N	158_E	0.618	0.43
458_E	466_D	0.618	0.43
262_A	321_T	0.618	0.43
48_T	304_G	0.618	0.43
23_F	347_A	0.616	0.43
239_G	246_A	0.615	0.43
233_R	283_D	0.615	0.43
185_A	385_I	0.615	0.43
123_V	165_V	0.615	0.43
267_L	274_R	0.613	0.43
85_N	399_G	0.612	0.42
96_E	129_R	0.611	0.42
273_A	374_F	0.609	0.42
258_F	262_A	0.607	0.42
29_R	333_Q	0.607	0.42
283_D	344_P	0.607	0.42
118_Q	137_V	0.605	0.42
79_L	283_D	0.605	0.42
323_S	470_V	0.604	0.42
82_L	94_E	0.603	0.42
204_Q	457_A	0.603	0.42
321_T	454_Y	0.603	0.42
246_A	259_I	0.602	0.41
102_D	226_R	0.602	0.41
151_T	196_R	0.601	0.41
294_A	297_A	0.600	0.41
384_V	434_K	0.600	0.41
29_R	56_V	0.598	0.41
233_R	367_A	0.598	0.41
72_A	76_E	0.596	0.41
267_L	270_I	0.595	0.41
150_A	185_A	0.595	0.41
112_V	135_A	0.594	0.41
278_A	300_D	0.593	0.41
96_E	137_V	0.593	0.41
37_P	85_N	0.589	0.40
129_R	274_R	0.588	0.40
180_I	197_V	0.587	0.40
243_T	272_S	0.586	0.40
48_T	340_P	0.586	0.40
143_T	204_Q	0.586	0.40
65_T	73_M	0.584	0.40
76_E	223_S	0.582	0.39
73_M	80_G	0.582	0.39
269_V	453_G	0.582	0.39
373_Y	440_E	0.581	0.39
115_A	138_V	0.580	0.39
44_T	285_V	0.579	0.39
96_E	130_S	0.578	0.39
151_T	195_E	0.578	0.39
58_S	64_V	0.578	0.39
79_L	304_G	0.577	0.39
278_A	459_S	0.577	0.39
75_R	467_A	0.576	0.39
79_L	233_R	0.576	0.39
277_K	304_G	0.576	0.39
140_D	205_H	0.574	0.39
85_N	453_G	0.573	0.39
44_T	343_V	0.572	0.39
225_A	228_Q	0.572	0.39
464_K	467_A	0.571	0.38
275_E	278_A	0.571	0.38
21_L	221_H	0.570	0.38
124_D	145_R	0.569	0.38
292_R	340_P	0.568	0.38
46_V	81_V	0.568	0.38
487_I	490_E	0.564	0.38
45_R	344_P	0.564	0.38
186_L	230_G	0.563	0.38
21_L	26_V	0.562	0.38
263_H	453_G	0.562	0.38
135_A	221_H	0.561	0.37
289_V	384_V	0.561	0.37
40_A	457_A	0.561	0.37
177_P	203_E	0.560	0.37
75_R	380_A	0.560	0.37
123_V	218_R	0.560	0.37
44_T	52_L	0.559	0.37
105_V	189_M	0.559	0.37
261_C	290_G	0.559	0.37
201_N	207_V	0.558	0.37
155_P	190_Y	0.557	0.37
283_D	367_A	0.557	0.37
404_M	421_E	0.556	0.37
448_I	452_M	0.555	0.37
45_R	67_S	0.555	0.37
388_N	482_P	0.555	0.37
142_D	205_H	0.555	0.37
331_V	335_A	0.555	0.37
284_V	303_D	0.554	0.37
183_R	186_L	0.554	0.37
193_K	277_K	0.552	0.37
72_A	185_A	0.552	0.37
20_A	471_R	0.552	0.37
394_Q	430_A	0.551	0.36
251_E	274_R	0.551	0.36
259_I	272_S	0.550	0.36
236_V	249_V	0.549	0.36
98_V	255_D	0.548	0.36
313_S	451_G	0.548	0.36
37_P	453_G	0.548	0.36
415_D	419_D	0.547	0.36
28_L	86_M	0.547	0.36
111_V	264_A	0.547	0.36
67_S	473_S	0.546	0.36
451_G	455_V	0.545	0.36
38_D	416_D	0.545	0.36
217_E	226_R	0.544	0.36
51_E	228_Q	0.544	0.36
276_I	458_E	0.543	0.36
73_M	76_E	0.542	0.36
136_P	206_L	0.542	0.36
124_D	219_R	0.541	0.36
286_V	304_G	0.541	0.36
240_P	268_N	0.541	0.36
103_E	110_N	0.541	0.36
284_V	342_G	0.540	0.35
442_H	450_S	0.540	0.35
138_V	205_H	0.539	0.35
86_M	406_S	0.539	0.35
85_N	412_Y	0.538	0.35
401_V	473_S	0.538	0.35
167_E	191_E	0.537	0.35
373_Y	434_K	0.535	0.35
72_A	307_V	0.535	0.35
69_L	434_K	0.533	0.35
311_P	318_R	0.533	0.35
366_D	436_S	0.533	0.35
127_M	185_A	0.532	0.35
339_A	342_G	0.532	0.35
423_V	453_G	0.532	0.35
130_S	150_A	0.530	0.35
336_D	468_E	0.530	0.35
96_E	100_R	0.528	0.34
149_S	152_D	0.528	0.34
184_D	188_L	0.527	0.34
299_V	344_P	0.526	0.34
40_A	231_R	0.525	0.34
459_S	467_A	0.525	0.34
69_L	225_A	0.525	0.34
262_A	449_Q	0.524	0.34
344_P	402_G	0.524	0.34
384_V	439_S	0.523	0.34
306_K	318_R	0.523	0.34
147_I	170_T	0.523	0.34
304_G	307_V	0.522	0.34
235_G	258_F	0.522	0.34
44_T	124_D	0.522	0.34
264_A	289_V	0.521	0.34
180_I	207_V	0.521	0.34
38_D	268_N	0.521	0.34
374_F	444_L	0.521	0.34
39_D	463_F	0.520	0.34
296_E	336_D	0.520	0.34
343_V	366_D	0.520	0.34
270_I	273_A	0.519	0.34
163_D	168_A	0.519	0.34
289_V	337_V	0.518	0.33
289_V	336_D	0.518	0.33
104_L	107_D	0.518	0.33
190_Y	194_I	0.518	0.33
293_E	297_A	0.518	0.33
391_K	434_K	0.517	0.33
388_N	430_A	0.516	0.33
329_T	388_N	0.516	0.33
134_G	149_S	0.515	0.33
62_D	83_H	0.515	0.33
457_A	463_F	0.515	0.33
295_A	341_A	0.515	0.33
82_L	294_A	0.515	0.33
183_R	187_E	0.514	0.33
40_A	269_V	0.513	0.33
40_A	57_L	0.512	0.33
59_A	148_I	0.512	0.33
362_A	486_M	0.512	0.33
87_D	257_L	0.512	0.33
76_E	370_L	0.512	0.33
48_T	367_A	0.512	0.33
68_R	466_D	0.511	0.33
69_L	72_A	0.511	0.33
184_D	238_V	0.511	0.33
142_D	358_A	0.510	0.33
186_L	215_I	0.509	0.33
321_T	476_G	0.509	0.33
42_V	459_S	0.508	0.33
148_I	289_V	0.508	0.33
334_V	361_I	0.508	0.33
145_R	181_T	0.508	0.33
90_R	406_S	0.508	0.33
56_V	368_V	0.508	0.33
119_T	162_S	0.508	0.33
101_A	106_I	0.507	0.32
105_V	226_R	0.507	0.32
43_A	142_D	0.507	0.32
305_I	345_V	0.506	0.32
79_L	235_G	0.506	0.32
143_T	274_R	0.505	0.32
311_P	356_D	0.505	0.32
84_Q	239_G	0.505	0.32
343_V	365_A	0.505	0.32
165_V	392_Y	0.505	0.32
103_E	253_G	0.504	0.32
48_T	57_L	0.504	0.32
18_P	329_T	0.504	0.32
106_I	144_V	0.503	0.32
395_Y	399_G	0.503	0.32
173_V	198_P	0.503	0.32
44_T	225_A	0.502	0.32
47_S	367_A	0.502	0.32
235_G	238_V	0.502	0.32
250_D	257_L	0.501	0.32
44_T	304_G	0.501	0.32
405_Q	440_E	0.501	0.32
81_V	282_A	0.500	0.32
100_R	388_N	0.500	0.32
306_K	311_P	0.500	0.32

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
3usbA	4	0.8617	100	0.456	Contact Map
2cu0A	4	0.7134	100	0.473	Contact Map
4af0A	3	0.7134	100	0.485	Contact Map
1vrdA	3	0.6353	100	0.49	Contact Map
1jcnA	6	0.7575	100	0.507	Contact Map
1zfjA	4	0.9399	100	0.523	Contact Map
1me8A	3	0.6774	100	0.54	Contact Map
4fxsA	3	0.9238	100	0.567	Contact Map
5ahnA	3	0.5872	100	0.57	Contact Map
4zqmA	3	0.6573	100	0.641	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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