Q9HQR8 - HALSA - GREMLIN Contacts

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Q9HQR8 - Uncharacterized protein

UniProt:	Q9HQR8	Sequences: MSRRPSPNADVCVIGAGPAGGLIADRLASDGHSVVVLEAGPRFDAADRERRMERSIRPAHGPASVWEMGGPRDAYASTGDRYYPLNAARVKGVGGSTLHWQGMVMRLHEQDFRLASATGVGADWPFDYDTLKPYYAAAESALGVSGASDNPFAPPREQPHPQPAFPPSYSDSLFADACESLGIATHSVPNARLSAGRETRRACVGYGTCQPVCPSGAKYDATVHVDRATDAGARVIDEAPVQRLEHDAAGDRVTGAVYATPDGTTHRQSATEFVLAAGGIETPRLLLLSDSDRYPDGLANSSGLVGRYFMDHLFAGAGGTLDEPTRQNHVGFNTTESHQYYDRPDGSRGAIKLEFLNYAGPSPAEMALSGDDWGDAMCDRIRDASGTHIAVGGLVEQQPRPENRVRLHPERTDVHGNPVPDVVWSLSAYERRTIERANEIQREILTELGADIEWTVGPEDTGPAFHHMGTTRMGTDPAESVVDPRLRTHDLSNLSVASSSVFPTAGAMNPTLTIAALALKAADHIAARL	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	529 (488)
Sequences:	11302 (8317)
Seq/√Len:	376.5

ECOLI - BETA
HALSA - Q9HQR8

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
244_L	253_V	3.498	1.00
258_Y	268_Q	3.439	1.00
127_D	130_T	3.402	1.00
243_R	257_V	3.210	1.00
483_D	487_R	3.207	1.00
474_G	480_S	3.142	1.00
41_P	238_E	3.112	1.00
245_E	257_V	3.068	1.00
497_A	521_A	3.012	1.00
402_E	427_S	2.987	1.00
140_S	156_R	2.982	1.00
284_R	288_L	2.942	1.00
499_S	514_I	2.924	1.00
134_Y	523_D	2.915	1.00
18_P	97_T	2.906	1.00
257_V	265_T	2.895	1.00
131_L	516_A	2.852	1.00
282_T	471_T	2.835	1.00
180_S	449_G	2.809	1.00
294_Y	301_S	2.674	1.00
482_V	501_V	2.592	1.00
272_E	495_S	2.536	1.00
257_V	267_R	2.467	1.00
411_R	416_G	2.420	1.00
8_N	269_S	2.401	1.00
471_T	500_S	2.336	1.00
307_R	406_R	2.318	1.00
402_E	429_Y	2.315	1.00
486_L	521_A	2.300	1.00
413_D	416_G	2.285	1.00
116_S	127_D	2.252	1.00
9_A	35_V	2.219	1.00
109_E	129_D	2.202	1.00
514_I	518_A	2.192	1.00
106_R	139_E	2.151	1.00
236_I	239_A	2.150	1.00
25_D	29_S	2.116	1.00
179_E	185_T	2.092	1.00
428_A	432_R	2.081	1.00
242_Q	257_V	2.047	1.00
68_M	281_E	2.026	1.00
35_V	268_Q	2.021	1.00
520_K	524_H	1.994	1.00
92_G	98_L	1.988	1.00
252_R	492_S	1.988	1.00
242_Q	265_T	1.979	1.00
252_R	493_N	1.975	1.00
245_E	255_G	1.974	1.00
287_L	409_P	1.964	1.00
35_V	236_I	1.951	1.00
502_F	517_L	1.948	1.00
471_T	481_V	1.914	1.00
242_Q	259_A	1.907	1.00
245_E	267_R	1.904	1.00
255_G	273_F	1.902	1.00
30_D	526_A	1.890	1.00
241_V	285_L	1.890	1.00
37_L	239_A	1.888	1.00
239_A	258_Y	1.873	1.00
28_A	230_D	1.871	1.00
440_I	443_E	1.856	1.00
12_C	268_Q	1.854	1.00
29_S	526_A	1.852	1.00
406_R	421_D	1.849	1.00
9_A	234_R	1.843	1.00
259_A	415_H	1.840	1.00
137_A	523_D	1.840	1.00
488_T	494_L	1.834	1.00
71_P	419_V	1.827	1.00
246_H	291_S	1.823	1.00
13_V	23_I	1.798	1.00
485_R	524_H	1.796	1.00
307_R	408_H	1.785	1.00
287_L	408_H	1.781	1.00
19_A	514_I	1.774	1.00
37_L	258_Y	1.772	1.00
37_L	236_I	1.765	1.00
221_A	515_A	1.763	1.00
468_M	505_A	1.763	1.00
104_V	512_L	1.747	1.00
423_V	426_L	1.742	1.00
293_R	301_S	1.734	1.00
77_S	421_D	1.712	1.00
410_E	419_V	1.709	1.00
181_L	447_E	1.702	1.00
247_D	254_T	1.697	1.00
240_P	415_H	1.693	1.00
281_E	284_R	1.689	1.00
26_R	519_L	1.678	1.00
52_M	55_S	1.675	1.00
12_C	35_V	1.675	1.00
246_H	251_D	1.674	1.00
176_D	179_E	1.673	1.00
11_V	32_H	1.669	1.00
501_V	517_L	1.654	1.00
300_N	491_L	1.652	1.00
442_R	455_T	1.642	1.00
90_V	96_S	1.641	1.00
453_E	458_P	1.636	1.00
93_V	237_D	1.632	1.00
18_P	511_T	1.616	1.00
309_F	470_T	1.616	1.00
123_D	130_T	1.610	1.00
480_S	489_H	1.610	1.00
410_E	416_G	1.600	1.00
246_H	299_A	1.597	1.00
134_Y	137_A	1.588	1.00
137_A	519_L	1.582	1.00
476_D	479_E	1.577	1.00
140_S	160_H	1.569	1.00
107_L	112_F	1.566	1.00
310_M	404_R	1.559	1.00
93_V	235_V	1.558	1.00
497_A	518_A	1.555	1.00
472_R	477_P	1.555	1.00
21_G	221_A	1.550	1.00
37_L	256_A	1.547	1.00
114_L	504_T	1.544	1.00
304_L	479_E	1.523	1.00
138_A	515_A	1.523	1.00
259_A	265_T	1.518	1.00
16_A	93_V	1.504	1.00
8_N	271_T	1.502	1.00
301_S	490_D	1.492	1.00
274_V	525_I	1.470	1.00
511_T	515_A	1.456	1.00
23_I	497_A	1.449	1.00
14_I	244_L	1.448	1.00
258_Y	266_H	1.442	1.00
159_P	223_V	1.436	1.00
254_T	269_S	1.426	1.00
245_E	254_T	1.393	1.00
122_A	484_P	1.380	1.00
132_K	136_A	1.379	1.00
219_Y	223_V	1.374	1.00
319_G	445_L	1.364	1.00
32_H	526_A	1.362	1.00
22_L	515_A	1.347	1.00
486_L	501_V	1.346	1.00
114_L	118_T	1.345	1.00
16_A	21_G	1.332	1.00
89_R	96_S	1.330	1.00
280_I	407_L	1.328	1.00
71_P	421_D	1.327	1.00
251_D	492_S	1.322	1.00
87_A	280_I	1.320	1.00
71_P	410_E	1.307	1.00
287_L	307_R	1.306	1.00
293_R	307_R	1.301	1.00
36_V	233_A	1.295	1.00
172_S	176_D	1.292	1.00
282_T	496_V	1.283	1.00
320_T	454_W	1.283	1.00
28_A	233_A	1.282	1.00
477_P	480_S	1.277	1.00
97_T	221_A	1.277	1.00
224_H	519_L	1.266	1.00
39_A	66_W	1.263	1.00
313_L	461_T	1.263	1.00
16_A	36_V	1.252	1.00
285_L	288_L	1.250	1.00
274_V	497_A	1.244	1.00
338_H	342_D	1.241	1.00
432_R	435_E	1.239	1.00
121_G	484_P	1.233	1.00
294_Y	298_L	1.230	1.00
472_R	479_E	1.230	1.00
138_A	224_H	1.228	1.00
140_S	158_Q	1.223	1.00
287_L	293_R	1.223	1.00
246_H	250_G	1.211	1.00
253_V	273_F	1.206	1.00
339_Q	345_D	1.202	1.00
304_L	308_Y	1.201	1.00
175_A	179_E	1.199	1.00
69_G	84_P	1.182	1.00
180_S	447_E	1.181	1.00
339_Q	343_R	1.174	1.00
279_G	283_P	1.172	1.00
18_P	515_A	1.170	1.00
468_M	510_P	1.168	1.00
160_H	219_Y	1.165	1.00
491_L	494_L	1.154	1.00
308_Y	472_R	1.153	1.00
242_Q	415_H	1.151	1.00
39_A	91_K	1.149	1.00
143_G	163_P	1.143	1.00
25_D	228_A	1.137	1.00
130_T	520_K	1.126	1.00
510_P	514_I	1.125	1.00
244_L	275_L	1.123	1.00
408_H	419_V	1.123	1.00
453_E	456_V	1.121	1.00
116_S	123_D	1.120	1.00
432_R	436_R	1.117	1.00
22_L	224_H	1.116	1.00
109_E	128_Y	1.116	1.00
33_S	234_R	1.115	1.00
375_D	379_D	1.115	1.00
261_P	266_H	1.112	1.00
291_S	491_L	1.111	1.00
308_Y	404_R	1.104	1.00
107_L	135_Y	1.102	1.00
33_S	232_G	1.102	1.00
176_D	180_S	1.102	1.00
32_H	271_T	1.100	1.00
112_F	513_T	1.100	1.00
477_P	489_H	1.097	1.00
135_Y	516_A	1.087	1.00
21_G	36_V	1.086	1.00
429_Y	432_R	1.082	1.00
448_L	451_D	1.080	1.00
246_H	491_L	1.079	1.00
247_D	250_G	1.079	1.00
436_R	439_E	1.077	1.00
70_G	87_A	1.076	1.00
376_A	379_D	1.076	1.00
302_S	489_H	1.076	1.00
487_R	492_S	1.074	1.00
406_R	423_V	1.069	1.00
81_R	459_E	1.067	1.00
280_I	420_P	1.067	1.00
288_L	414_V	1.061	1.00
14_I	277_A	1.061	1.00
475_T	484_P	1.060	1.00
333_N	336_E	1.048	1.00
336_E	339_Q	1.044	1.00
96_S	99_H	1.044	1.00
443_E	446_T	1.041	1.00
247_D	269_S	1.038	1.00
475_T	489_H	1.037	1.00
408_H	421_D	1.029	1.00
136_A	154_P	1.021	1.00
521_A	525_I	1.019	1.00
482_V	496_V	1.019	1.00
109_E	113_R	1.018	1.00
270_A	273_F	1.018	1.00
160_H	214_P	1.018	1.00
256_A	273_F	1.013	1.00
219_Y	222_T	1.009	1.00
374_G	378_C	1.009	1.00
23_I	518_A	1.004	1.00
334_T	338_H	1.002	1.00
428_A	431_R	1.002	1.00
245_E	269_S	0.996	1.00
9_A	12_C	0.995	1.00
105_M	509_N	0.993	1.00
251_D	300_N	0.990	1.00
183_I	440_I	0.988	1.00
523_D	526_A	0.986	1.00
142_L	160_H	0.986	1.00
487_R	495_S	0.985	1.00
217_A	344_P	0.978	1.00
22_L	25_D	0.977	1.00
277_A	285_L	0.974	1.00
521_A	524_H	0.971	1.00
158_Q	224_H	0.968	1.00
43_F	92_G	0.968	1.00
332_F	336_E	0.967	1.00
26_R	137_A	0.967	1.00
23_I	522_A	0.966	1.00
287_L	407_L	0.965	1.00
236_I	258_Y	0.963	1.00
435_E	439_E	0.963	1.00
134_Y	520_K	0.960	1.00
374_G	379_D	0.959	1.00
23_I	274_V	0.959	1.00
510_P	513_T	0.956	1.00
305_V	481_V	0.956	1.00
209_C	213_C	0.954	1.00
242_Q	288_L	0.952	1.00
105_M	508_M	0.952	1.00
304_L	472_R	0.950	1.00
14_I	256_A	0.948	1.00
12_C	270_A	0.943	1.00
174_F	178_C	0.943	1.00
486_L	524_H	0.943	1.00
13_V	24_A	0.938	1.00
279_G	468_M	0.937	1.00
112_F	135_Y	0.936	1.00
71_P	77_S	0.928	1.00
506_G	513_T	0.928	1.00
118_T	504_T	0.926	1.00
43_F	98_L	0.924	1.00
277_A	281_E	0.921	1.00
236_I	261_P	0.919	1.00
28_A	34_V	0.915	1.00
42_R	93_V	0.914	1.00
138_A	519_L	0.912	1.00
28_A	232_G	0.908	1.00
77_S	422_V	0.900	1.00
476_D	480_S	0.899	1.00
394_L	441_Q	0.898	1.00
310_M	505_A	0.895	1.00
98_L	220_D	0.892	1.00
140_S	155_P	0.891	1.00
116_S	121_G	0.891	1.00
253_V	494_L	0.890	1.00
61_G	65_V	0.886	1.00
337_S	340_Y	0.880	1.00
106_R	132_K	0.880	1.00
78_T	82_Y	0.880	1.00
209_C	356_L	0.879	1.00
276_A	497_A	0.878	1.00
311_D	463_P	0.877	1.00
466_H	509_N	0.877	1.00
482_V	486_L	0.875	1.00
482_V	489_H	0.873	1.00
12_C	256_A	0.873	1.00
106_R	135_Y	0.872	1.00
53_E	56_I	0.870	1.00
246_H	254_T	0.869	1.00
396_E	437_A	0.868	1.00
39_A	240_P	0.866	1.00
330_V	334_T	0.863	1.00
497_A	525_I	0.862	1.00
244_L	494_L	0.862	1.00
25_D	28_A	0.861	1.00
114_L	117_A	0.861	1.00
203_C	209_C	0.859	1.00
244_L	273_F	0.858	1.00
134_Y	519_L	0.855	1.00
28_A	31_G	0.855	1.00
80_D	83_Y	0.855	1.00
113_R	117_A	0.851	1.00
429_Y	433_T	0.851	1.00
374_G	377_M	0.849	1.00
180_S	448_L	0.848	1.00
304_L	480_S	0.848	1.00
243_R	299_A	0.844	1.00
287_L	305_V	0.841	1.00
405_V	409_P	0.841	1.00
331_G	335_T	0.838	1.00
401_P	404_R	0.831	1.00
394_L	445_L	0.830	1.00
105_M	189_P	0.828	1.00
12_C	273_F	0.827	1.00
431_R	435_E	0.827	1.00
279_G	499_S	0.824	1.00
299_A	488_T	0.822	1.00
445_L	450_A	0.822	1.00
351_I	354_E	0.820	1.00
334_T	337_S	0.818	1.00
380_R	383_D	0.818	1.00
51_R	54_R	0.817	1.00
88_A	465_F	0.815	1.00
283_P	470_T	0.814	1.00
11_V	274_V	0.813	1.00
10_D	32_H	0.811	1.00
14_I	285_L	0.809	1.00
37_L	268_Q	0.809	1.00
127_D	133_P	0.807	1.00
138_A	512_L	0.807	1.00
222_T	226_D	0.807	1.00
62_P	65_V	0.807	1.00
21_G	225_V	0.806	1.00
77_S	80_D	0.806	1.00
350_A	354_E	0.805	1.00
488_T	491_L	0.805	1.00
434_I	437_A	0.804	1.00
335_T	338_H	0.803	1.00
246_H	253_V	0.803	1.00
97_T	511_T	0.802	1.00
206_Y	209_C	0.801	1.00
236_I	268_Q	0.801	1.00
495_S	524_H	0.800	1.00
51_R	55_S	0.799	1.00
499_S	502_F	0.798	1.00
9_A	236_I	0.797	1.00
130_T	133_P	0.796	1.00
178_C	444_I	0.794	1.00
7_P	266_H	0.794	1.00
360_G	364_A	0.792	1.00
25_D	227_R	0.791	1.00
275_L	282_T	0.789	1.00
336_E	347_S	0.789	1.00
455_T	458_P	0.788	1.00
7_P	33_S	0.786	1.00
293_R	408_H	0.783	1.00
236_I	266_H	0.783	1.00
145_S	155_P	0.782	1.00
175_A	185_T	0.782	1.00
89_R	284_R	0.781	1.00
31_G	526_A	0.780	1.00
247_D	252_R	0.780	1.00
44_D	47_D	0.779	1.00
173_L	176_D	0.779	1.00
189_P	207_G	0.778	1.00
322_D	451_D	0.773	1.00
121_G	475_T	0.773	1.00
214_P	219_Y	0.771	1.00
239_A	268_Q	0.771	1.00
92_G	99_H	0.765	1.00
338_H	343_R	0.765	1.00
331_G	334_T	0.764	1.00
298_L	301_S	0.762	1.00
128_Y	132_K	0.760	1.00
110_Q	113_R	0.759	1.00
374_G	381_I	0.759	1.00
359_A	440_I	0.758	1.00
14_I	275_L	0.757	1.00
183_I	206_Y	0.756	1.00
392_G	445_L	0.756	1.00
9_A	33_S	0.755	1.00
376_A	380_R	0.754	1.00
107_L	506_G	0.754	1.00
310_M	468_M	0.753	1.00
291_S	299_A	0.752	1.00
272_E	525_I	0.752	1.00
330_V	333_N	0.751	1.00
11_V	272_E	0.750	1.00
87_A	422_V	0.749	1.00
286_L	471_T	0.749	1.00
337_S	341_Y	0.748	1.00
397_Q	464_A	0.745	1.00
36_V	225_V	0.745	1.00
247_D	251_D	0.745	1.00
178_C	183_I	0.745	1.00
339_Q	342_D	0.741	1.00
30_D	230_D	0.741	1.00
119_G	123_D	0.741	1.00
481_V	488_T	0.739	1.00
452_I	456_V	0.739	1.00
244_L	256_A	0.736	1.00
139_E	153_A	0.736	1.00
104_V	212_V	0.735	1.00
69_G	86_N	0.735	1.00
177_A	449_G	0.733	1.00
238_E	261_P	0.732	1.00
280_I	467_H	0.732	1.00
396_E	441_Q	0.731	1.00
338_H	341_Y	0.731	1.00
200_R	203_C	0.728	1.00
134_Y	138_A	0.725	1.00
311_D	424_W	0.725	1.00
41_P	237_D	0.723	1.00
26_R	522_A	0.719	1.00
118_T	121_G	0.718	1.00
223_V	227_R	0.718	1.00
176_D	185_T	0.716	1.00
203_C	213_C	0.715	1.00
70_G	422_V	0.715	1.00
29_S	230_D	0.715	1.00
71_P	84_P	0.713	1.00
90_V	99_H	0.711	1.00
251_D	299_A	0.710	1.00
24_A	36_V	0.707	1.00
379_D	382_R	0.706	1.00
31_G	34_V	0.703	0.99
304_L	481_V	0.702	0.99
282_T	498_S	0.701	0.99
242_Q	285_L	0.700	0.99
153_A	157_E	0.698	0.99
442_R	446_T	0.698	0.99
65_V	99_H	0.697	0.99
163_P	210_Q	0.697	0.99
502_F	506_G	0.697	0.99
104_V	138_A	0.696	0.99
13_V	274_V	0.696	0.99
360_G	363_P	0.695	0.99
346_G	349_G	0.694	0.99
349_G	352_K	0.694	0.99
243_R	289_S	0.694	0.99
502_F	514_I	0.690	0.99
375_D	378_C	0.688	0.99
468_M	499_S	0.687	0.99
26_R	29_S	0.685	0.99
425_S	431_R	0.685	0.99
49_E	92_G	0.684	0.99
291_S	294_Y	0.681	0.99
452_I	455_T	0.680	0.99
406_R	419_V	0.679	0.99
66_W	91_K	0.679	0.99
128_Y	131_L	0.679	0.99
376_A	381_I	0.678	0.99
116_S	122_A	0.678	0.99
239_A	266_H	0.678	0.99
293_R	298_L	0.677	0.99
178_C	206_Y	0.676	0.99
255_G	267_R	0.675	0.99
52_M	56_I	0.673	0.99
486_L	517_L	0.673	0.99
293_R	303_G	0.672	0.99
115_A	502_F	0.671	0.99
427_S	431_R	0.671	0.99
13_V	20_G	0.669	0.99
25_D	230_D	0.666	0.99
122_A	475_T	0.663	0.99
112_F	506_G	0.662	0.99
446_T	451_D	0.662	0.99
10_D	271_T	0.661	0.99
141_A	163_P	0.660	0.99
62_P	67_E	0.660	0.99
309_F	467_H	0.660	0.99
308_Y	469_G	0.659	0.99
403_N	426_L	0.658	0.99
113_R	116_S	0.658	0.99
204_V	360_G	0.657	0.99
418_P	422_V	0.657	0.99
205_G	212_V	0.657	0.99
352_K	355_F	0.657	0.99
133_P	523_D	0.657	0.99
362_S	436_R	0.656	0.99
400_R	507_A	0.656	0.99
299_A	302_S	0.654	0.99
398_Q	433_T	0.654	0.99
374_G	380_R	0.654	0.99
25_D	158_Q	0.653	0.99
284_R	409_P	0.652	0.99
439_E	442_R	0.651	0.99
340_Y	344_P	0.650	0.99
317_A	438_N	0.650	0.99
483_D	489_H	0.648	0.99
296_D	409_P	0.648	0.99
350_A	353_L	0.646	0.99
153_A	188_V	0.646	0.99
11_V	27_L	0.644	0.99
290_D	303_G	0.644	0.99
113_R	127_D	0.643	0.99
495_S	525_I	0.642	0.99
108_H	203_C	0.642	0.99
167_P	172_S	0.642	0.99
141_A	210_Q	0.642	0.99
34_V	233_A	0.641	0.99
29_S	137_A	0.640	0.99
270_A	494_L	0.639	0.99
91_K	240_P	0.637	0.99
326_R	329_H	0.637	0.99
108_H	507_A	0.636	0.99
520_K	523_D	0.636	0.99
112_F	131_L	0.634	0.99
447_E	450_A	0.631	0.99
144_V	155_P	0.631	0.99
356_L	359_A	0.631	0.99
116_S	130_T	0.630	0.99
354_E	358_Y	0.629	0.99
181_L	443_E	0.626	0.99
13_V	25_D	0.626	0.99
379_D	383_D	0.626	0.99
355_F	358_Y	0.622	0.99
332_F	335_T	0.621	0.99
437_A	441_Q	0.617	0.99
374_G	383_D	0.617	0.99
295_P	298_L	0.616	0.99
377_M	381_I	0.615	0.99
473_M	482_V	0.615	0.99
352_K	359_A	0.615	0.99
13_V	34_V	0.614	0.99
305_V	471_T	0.614	0.99
300_N	489_H	0.614	0.99
283_P	305_V	0.614	0.99
275_L	285_L	0.614	0.99
159_P	224_H	0.612	0.99
377_M	382_R	0.611	0.99
258_Y	261_P	0.611	0.99
171_D	175_A	0.611	0.99
436_R	440_I	0.610	0.99
377_M	380_R	0.609	0.99
304_L	477_P	0.608	0.99
181_L	444_I	0.608	0.99
378_C	382_R	0.607	0.98
314_F	395_V	0.606	0.98
8_N	33_S	0.606	0.98
205_G	210_Q	0.603	0.98
30_D	232_G	0.603	0.98
309_F	407_L	0.602	0.98
354_E	359_A	0.601	0.98
7_P	234_R	0.601	0.98
112_F	115_A	0.600	0.98
386_G	389_I	0.600	0.98
471_T	482_V	0.600	0.98
365_E	372_D	0.600	0.98
184_A	202_A	0.599	0.98
154_P	157_E	0.599	0.98
87_A	424_W	0.599	0.98
61_G	64_S	0.598	0.98
315_A	434_I	0.598	0.98
312_H	466_H	0.596	0.98
341_Y	344_P	0.596	0.98
443_E	447_E	0.596	0.98
444_I	447_E	0.596	0.98
139_E	154_P	0.595	0.98
203_C	210_Q	0.594	0.98
502_F	510_P	0.594	0.98
314_F	464_A	0.593	0.98
304_L	489_H	0.593	0.98
113_R	129_D	0.593	0.98
284_R	287_L	0.592	0.98
291_S	300_N	0.591	0.98
303_G	307_R	0.588	0.98
246_H	300_N	0.588	0.98
7_P	236_I	0.587	0.98
213_C	217_A	0.586	0.98
131_L	135_Y	0.585	0.98
497_A	522_A	0.585	0.98
87_A	467_H	0.584	0.98
474_G	479_E	0.584	0.98
261_P	264_T	0.582	0.98
286_L	291_S	0.582	0.98
357_N	361_P	0.580	0.98
325_T	329_H	0.580	0.98
317_A	441_Q	0.580	0.98
253_V	491_L	0.580	0.98
60_H	65_V	0.580	0.98
240_P	284_R	0.579	0.98
79_G	426_L	0.578	0.98
308_Y	470_T	0.578	0.98
321_L	392_G	0.577	0.98
114_L	400_R	0.576	0.98
68_M	420_P	0.576	0.98
320_T	453_E	0.575	0.98
475_T	480_S	0.575	0.98
253_V	493_N	0.575	0.98
342_D	345_D	0.574	0.98
13_V	28_A	0.572	0.98
29_S	519_L	0.572	0.98
425_S	461_T	0.571	0.98
441_Q	445_L	0.571	0.98
203_C	206_Y	0.571	0.98
375_D	380_R	0.569	0.98
202_A	205_G	0.569	0.98
121_G	130_T	0.567	0.98
20_G	276_A	0.565	0.98
43_F	226_D	0.565	0.98
413_D	418_P	0.563	0.98
312_H	509_N	0.563	0.98
469_G	472_R	0.563	0.98
241_V	277_A	0.563	0.98
472_R	480_S	0.562	0.98
217_A	340_Y	0.562	0.98
123_D	484_P	0.561	0.97
254_T	267_R	0.561	0.97
177_A	180_S	0.561	0.97
16_A	19_A	0.560	0.97
476_D	489_H	0.560	0.97
212_V	511_T	0.560	0.97
23_I	276_A	0.559	0.97
431_R	434_I	0.559	0.97
144_V	148_S	0.558	0.97
355_F	359_A	0.555	0.97
496_V	500_S	0.553	0.97
359_A	362_S	0.552	0.97
425_S	434_I	0.552	0.97
281_E	285_L	0.550	0.97
159_P	515_A	0.550	0.97
70_G	77_S	0.549	0.97
378_C	381_I	0.549	0.97
172_S	208_T	0.549	0.97
80_D	461_T	0.548	0.97
452_I	458_P	0.548	0.97
106_R	136_A	0.547	0.97
474_G	489_H	0.547	0.97
318_G	393_G	0.546	0.97
310_M	469_G	0.546	0.97
139_E	512_L	0.545	0.97
468_M	502_F	0.544	0.97
339_Q	347_S	0.544	0.97
30_D	34_V	0.544	0.97
373_W	379_D	0.541	0.97
228_A	233_A	0.540	0.97
200_R	205_G	0.539	0.97
116_S	129_D	0.539	0.97
475_T	479_E	0.538	0.97
374_G	382_R	0.538	0.97
373_W	380_R	0.537	0.97
354_E	361_P	0.536	0.97
304_L	307_R	0.536	0.97
113_R	128_Y	0.535	0.97
204_V	215_S	0.535	0.97
372_D	376_A	0.533	0.97
136_A	158_Q	0.532	0.97
508_M	513_T	0.531	0.97
123_D	127_D	0.531	0.97
87_A	407_L	0.530	0.96
10_D	33_S	0.530	0.96
313_L	434_I	0.530	0.96
255_G	269_S	0.529	0.96
134_Y	524_H	0.529	0.96
60_H	64_S	0.528	0.96
238_E	262_D	0.527	0.96
89_R	281_E	0.527	0.96
177_A	447_E	0.525	0.96
217_A	222_T	0.525	0.96
72_R	84_P	0.525	0.96
313_L	424_W	0.524	0.96
350_A	355_F	0.522	0.96
28_A	228_A	0.522	0.96
9_A	268_Q	0.522	0.96
173_L	450_A	0.522	0.96
352_K	360_G	0.522	0.96
179_E	206_Y	0.521	0.96
302_S	491_L	0.519	0.96
61_G	67_E	0.519	0.96
133_P	520_K	0.519	0.96
496_V	501_V	0.518	0.96
26_R	523_D	0.518	0.96
277_A	282_T	0.517	0.96
137_A	224_H	0.516	0.96
49_E	98_L	0.516	0.96
357_N	363_P	0.516	0.96
242_Q	414_V	0.516	0.96
69_G	72_R	0.515	0.96
18_P	221_A	0.515	0.96
254_T	257_V	0.514	0.96
110_Q	114_L	0.514	0.96
310_M	504_T	0.514	0.96
142_L	163_P	0.513	0.96
155_P	158_Q	0.512	0.96
349_G	354_E	0.510	0.96
167_P	208_T	0.510	0.96
159_P	212_V	0.509	0.96
284_R	418_P	0.509	0.96
497_A	514_I	0.509	0.96
175_A	206_Y	0.509	0.96
186_H	189_P	0.508	0.96
321_L	325_T	0.508	0.96
340_Y	343_R	0.508	0.96
11_V	526_A	0.508	0.96
343_R	346_G	0.507	0.95
11_V	271_T	0.507	0.95
479_E	489_H	0.507	0.95
23_I	521_A	0.506	0.95
279_G	467_H	0.506	0.95
505_A	510_P	0.506	0.95
160_H	163_P	0.505	0.95
452_I	457_G	0.503	0.95
478_A	489_H	0.502	0.95
344_P	347_S	0.502	0.95
240_P	259_A	0.501	0.95
375_D	382_R	0.501	0.95
25_D	224_H	0.501	0.95
156_R	160_H	0.500	0.95

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
4h7uA	1	0.9641	100	0.259	Contact Map
3fimB	1	0.9584	100	0.262	Contact Map
3q9tA	2	0.9546	100	0.272	Contact Map
1gpeA	2	0.9565	100	0.281	Contact Map
4udqA	1	0.8847	100	0.284	Contact Map
3qvpA	1	0.9584	100	0.286	Contact Map
2jbvA	1	0.9244	100	0.301	Contact Map
4ha6A	2	0.9055	100	0.312	Contact Map
4mifA	4	0.9168	100	0.326	Contact Map
4z24A	2	0.9149	100	0.328	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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