GREMLIN Database
Q9HQP8 - Rhamnosyl transferase
UniProt: Q9HQP8 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 299 (242)
Sequences: 24410 (20909)
Seq/√Len: 1344.1

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
16_D95_A3.4291.00
165_R169_E3.1991.00
17_P48_E2.7611.00
80_T84_H2.6151.00
106_D202_G2.5491.00
8_S87_G2.4931.00
42_D67_T2.4511.00
50_M67_T2.4311.00
185_E189_R2.3751.00
13_V49_T2.3291.00
72_Q76_A2.3171.00
83_E173_T2.2701.00
89_V111_F2.2611.00
68_E80_T2.2611.00
100_E206_K2.2431.00
50_M54_E2.1961.00
31_R105_R2.1861.00
37_E64_Y2.1711.00
41_V81_G2.1621.00
110_T200_A2.0441.00
21_K25_H2.0381.00
116_V198_G2.0281.00
22_D208_P2.0211.00
7_V108_S1.9641.00
11_V38_V1.9341.00
167_V195_F1.9201.00
48_E51_Q1.8841.00
10_V81_G1.8491.00
8_S37_E1.8391.00
91_V162_A1.8331.00
76_A176_D1.8261.00
110_T198_G1.8091.00
99_V103_C1.8051.00
107_I162_A1.8051.00
66_H84_H1.8031.00
91_V104_L1.7981.00
22_D98_V1.7971.00
17_P52_V1.7801.00
11_V23_T1.7561.00
117_D164_R1.7531.00
50_M65_C1.7311.00
6_F88_D1.7231.00
124_Q206_K1.7221.00
15_N46_T1.7161.00
25_H56_F1.7111.00
91_V103_C1.6881.00
54_E67_T1.6471.00
102_T106_D1.6261.00
98_V206_K1.6091.00
21_K56_F1.6041.00
93_L99_V1.5801.00
40_V53_I1.5641.00
21_K55_A1.5321.00
118_Y197_M1.5311.00
103_C107_I1.5151.00
37_E87_G1.5151.00
78_R94_D1.5141.00
117_D195_F1.5091.00
42_D45_S1.5001.00
21_K52_V1.4821.00
89_V162_A1.4781.00
68_E72_Q1.4671.00
13_V40_V1.4521.00
80_T83_E1.4401.00
7_V104_L1.4331.00
66_H80_T1.4211.00
90_I165_R1.4151.00
6_F35_A1.4091.00
14_Y71_I1.3951.00
74_S78_R1.3811.00
25_H29_D1.3771.00
78_R92_F1.3651.00
167_V190_V1.3601.00
75_Y182_G1.3441.00
111_F162_A1.3421.00
64_Y84_H1.3361.00
175_D185_E1.3311.00
107_I121_C1.3291.00
105_R109_R1.3151.00
13_V16_D1.3131.00
106_D109_R1.3101.00
88_D164_R1.2831.00
170_A193_A1.2751.00
74_S182_G1.2731.00
33_A108_S1.2661.00
85_A165_R1.2551.00
8_S85_A1.2551.00
161_L187_G1.2451.00
82_I92_F1.2371.00
166_E170_A1.2321.00
108_S112_E1.2311.00
98_V208_P1.2281.00
41_V77_A1.2191.00
24_L38_V1.2131.00
7_V162_A1.2041.00
42_D50_M1.2011.00
15_N45_S1.1931.00
111_F119_V1.1871.00
16_D19_G1.1841.00
82_I168_I1.1801.00
68_E77_A1.1761.00
38_V63_I1.1701.00
8_S39_R1.1641.00
24_L56_F1.1571.00
29_D101_R1.1511.00
170_A195_F1.1451.00
122_N199_F1.1391.00
23_T93_L1.1381.00
126_Y206_K1.1361.00
106_D200_A1.1241.00
89_V108_S1.1231.00
26_A98_V1.1181.00
91_V99_V1.1151.00
13_V95_A1.1111.00
118_Y190_V1.1061.00
37_E86_G1.1051.00
33_A36_F1.0981.00
166_E169_E1.0951.00
54_E57_A1.0941.00
76_A80_T1.0831.00
124_Q203_I1.0801.00
123_V159_C1.0721.00
102_T105_R1.0711.00
43_N71_I1.0641.00
53_I65_C1.0461.00
27_L93_L1.0411.00
164_R167_V1.0391.00
11_V27_L1.0351.00
6_F86_G1.0301.00
55_A59_D1.0261.00
168_I186_F1.0241.00
103_C121_C1.0211.00
28_V60_H1.0181.00
110_T119_V1.0161.00
26_A99_V1.0121.00
98_V126_Y1.0071.00
115_D196_R1.0031.00
12_P77_A1.0001.00
6_F87_G0.9991.00
51_Q54_E0.9961.00
36_F104_L0.9911.00
31_R102_T0.9901.00
82_I90_I0.9831.00
25_H28_V0.9781.00
52_V56_F0.9781.00
107_I119_V0.9741.00
226_G229_Q0.9601.00
127_N131_T0.9561.00
48_E52_V0.9521.00
171_V193_A0.9471.00
28_V62_E0.9421.00
52_V55_A0.9241.00
68_E76_A0.9191.00
24_L40_V0.9141.00
110_T113_G0.9081.00
100_E124_Q0.8931.00
43_N77_A0.8921.00
9_V104_L0.8911.00
28_V63_I0.8901.00
106_D110_T0.8851.00
103_C204_V0.8831.00
74_S158_T0.8801.00
13_V53_I0.8761.00
51_Q55_A0.8721.00
158_T174_F0.8711.00
121_C204_V0.8681.00
31_R101_R0.8631.00
13_V20_V0.8571.00
64_Y86_G0.8541.00
136_T139_D0.8521.00
27_L99_V0.8411.00
78_R182_G0.8361.00
9_V27_L0.8361.00
74_S77_A0.8271.00
28_V56_F0.8271.00
9_V91_V0.8261.00
109_R113_G0.8161.00
19_G208_P0.7981.00
92_F174_F0.7971.00
74_S214_K0.7971.00
158_T161_L0.7931.00
69_T72_Q0.7911.00
25_H59_D0.7891.00
107_I111_F0.7841.00
55_A58_A0.7831.00
43_N73_S0.7821.00
57_A63_I0.7801.00
75_Y79_N0.7781.00
7_V91_V0.7771.00
41_V80_T0.7761.00
82_I85_A0.7761.00
39_R64_Y0.7751.00
167_V171_V0.7711.00
128_P131_T0.7701.00
72_Q77_A0.7701.00
111_F116_V0.7661.00
50_M53_I0.7631.00
5_P112_E0.7611.00
23_T26_A0.7611.00
159_C205_A0.7561.00
117_D196_R0.7551.00
125_M209_A0.7501.00
120_G199_F0.7491.00
126_Y208_P0.7491.00
149_Y152_R0.7471.00
186_F190_V0.7391.00
79_N173_T0.7341.00
9_V36_F0.7331.00
5_P88_D0.7311.00
163_V187_G0.7301.00
56_F60_H0.7281.00
27_L38_V0.7271.00
100_E103_C0.7191.00
213_L216_N0.7171.00
89_V164_R0.7171.00
126_Y130_E0.7151.00
16_D210_R0.7121.00
171_V190_V0.7101.00
100_E204_V0.7091.00
181_G184_K0.6991.00
20_V95_A0.6961.00
39_R81_G0.6961.00
54_E65_C0.6951.00
82_I173_T0.6951.00
117_D167_V0.6941.00
224_G227_Q0.6921.00
24_L28_V0.6921.00
77_A80_T0.6901.00
43_N72_Q0.6891.00
40_V63_I0.6881.00
20_V53_I0.6851.00
74_S94_D0.6841.00
39_R84_H0.6821.00
57_A65_C0.6801.00
60_H63_I0.6791.00
79_N176_D0.6771.00
43_N68_E0.6711.00
167_V170_A0.6691.00
46_T49_T0.6661.00
108_S162_A0.6651.00
69_T80_T0.6621.00
147_E151_R0.6621.00
88_D166_E0.6611.00
122_N201_E0.6601.00
106_D204_V0.6591.00
88_D112_E0.6551.00
175_D189_R0.6471.00
97_V205_A0.6451.00
85_A90_I0.6411.00
137_K140_L0.6401.00
72_Q80_T0.6401.00
163_V168_I0.6381.00
12_P43_N0.6351.00
64_Y67_T0.6331.00
163_V186_F0.6301.00
121_C160_A0.6301.00
10_V41_V0.6271.00
30_Q105_R0.6261.00
156_A161_L0.6251.00
79_N83_E0.6191.00
12_P95_A0.6171.00
44_D69_T0.6161.00
138_Y141_A0.6161.00
13_V42_D0.6151.00
120_G161_L0.6151.00
31_R34_P0.6111.00
114_S198_G0.6111.00
200_A203_I0.6101.00
20_V52_V0.6081.00
214_K217_I0.6041.00
56_F59_D0.6041.00
127_N130_E0.6031.00
136_T140_L0.6031.00
111_F164_R0.6001.00
21_K59_D0.5971.00
168_I173_T0.5951.00
27_L30_Q0.5941.00
230_L234_Y0.5921.00
221_T225_K0.5921.00
17_P21_K0.5911.00
12_P78_R0.5901.00
163_V190_V0.5901.00
79_N174_F0.5891.00
54_E58_A0.5881.00
222_R226_G0.5871.00
41_V68_E0.5851.00
110_T116_V0.5851.00
22_D25_H0.5841.00
44_D68_E0.5841.00
147_E154_R0.5831.00
120_G156_A0.5831.00
20_V49_T0.5821.00
6_F112_E0.5811.00
57_A60_H0.5751.00
169_E173_T0.5731.00
220_S223_I0.5721.00
137_K141_A0.5711.00
149_Y153_K0.5701.00
8_S165_R0.5691.00
15_N47_D0.5641.00
173_T186_F0.5631.00
14_Y43_N0.5621.00
6_F37_E0.5611.00
184_K188_N0.5601.00
226_G230_L0.5591.00
151_R154_R0.5591.00
91_V160_A0.5571.00
139_D142_M0.5561.00
93_L205_A0.5561.00
116_V119_V0.5561.00
33_A105_R0.5541.00
23_T97_V0.5521.00
33_A104_L0.5501.00
31_R36_F0.5491.00
156_A187_G0.5491.00
10_V85_A0.5481.00
109_R112_E0.5461.00
160_A205_A0.5461.00
17_P47_D0.5461.00
94_D182_G0.5431.00
12_P74_S0.5431.00
223_I227_Q0.5431.00
72_Q176_D0.5421.00
17_P49_T0.5421.00
123_V160_A0.5401.00
210_R213_L0.5391.00
228_V232_A0.5371.00
39_R85_A0.5351.00
28_V59_D0.5341.00
108_S111_F0.5331.00
229_Q233_G0.5321.00
38_V62_E0.5301.00
97_V207_H0.5301.00
6_F33_A0.5291.00
16_D74_S0.5291.00
30_Q99_V0.5291.00
191_S197_M0.5281.00
100_E203_I0.5281.00
141_A144_L0.5261.00
242_S245_R0.5241.00
115_D164_R0.5241.00
143_G146_V0.5221.00
6_F36_F0.5211.00
122_N203_I0.5211.00
243_Y246_Y0.5211.00
117_D194_G0.5201.00
53_I57_A0.5201.00
167_V194_G0.5201.00
148_H151_R0.5181.00
190_V195_F0.5171.00
11_V95_A0.5161.00
142_M145_P0.5131.00
117_D166_E0.5131.00
17_P20_V0.5121.00
107_I160_A0.5121.00
44_D71_I0.5101.00
114_S117_D0.5071.00
5_P33_A0.5071.00
138_Y142_M0.5021.00
30_Q104_L0.5021.00
159_C207_H0.5021.00
119_V200_A0.5001.00
213_L217_I0.5001.00
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
2d7iA 1 0.9967 100 0.295 Contact Map
3bcvA 2 0.5953 100 0.302 Contact Map
1xhbA 1 0.9699 100 0.316 Contact Map
2z86A 2 0.8395 100 0.319 Contact Map
3l7iA 4 0 100 0.327 Contact Map
5ajoA 1 0.9833 100 0.335 Contact Map
1qg8A 1 0.7425 100 0.337 Contact Map
4fixA 3 0.9967 100 0.389 Contact Map
4p02A 1 0.9431 100 0.413 Contact Map
2bo4A 4 0.9398 100 0.426 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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