Q9HQP4 - HALSA - GREMLIN Contacts

Home
GREMLIN
- Submit - Monomer
- Submit - Complex
Contacts
Metagenomics
- Contacts
- Structures
Structures
- List
Old Projects
- Complexes (2014)
- PFAM (2013)

Q9HQP4 - Uncharacterized protein

UniProt:	Q9HQP4	Sequences: MTDESDSTAHVSCIIPVYNDSVGIKNTLRSVVGQEYHGYDVYVVDNGSTDGSRRRVRNCAAESDDIQLLVEDEVQGSYAARKTGVQNAESDVLAFLDADETVDEDWLETALGAMQEQDVDYLGCNVELTCPEDTLVGRYNARTGFPVEEYLEDQNYAPTCALLVRRKVFEDVGPFDARLISGGDREFGDRVHDAGYEQGYAENATVYHPARTSLESLAKKNFRVGRGFCQKQRYYPERYGKPGIPPTPSGPSGGDDGDEPDASLTRLAFTLLSIAMLACRGVGYYYEFVVGEENDDIPAPTS	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	302 (242)
Sequences:	18343 (15659)
Seq/√Len:	1006.6

ECOLI - YIBD WCAA WCAE PGAC WBBL ARNC GTRB YAIP
BACSU - GGAA CGED EPSJ GGAB EPSH EPSE YFNE TUAG SPSA YWDF YDAM CSBB YKCC YKOT TAGF
HALSA - Q9HQP4 Q9HQP8 Q9HSC8 Q9HQP3 Q9HNK3 Q9HQQ6 Q9HR08 Q9HSB1
SULSO - Q7LXF7 Q97TZ0 Q97TY0 Q97W52 Q7LXY2 Q7LXG6 Q97X05 Q97YM4 Q97YG5 Q97WK7 Q97UK7 Q97YN4

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
166_R	170_E	3.425	1.00
20_D	98_A	3.397	1.00
21_S	51_G	2.788	1.00
109_T	203_N	2.664	1.00
83_T	87_N	2.638	1.00
12_S	90_S	2.480	1.00
186_E	190_R	2.419	1.00
17_V	52_S	2.372	1.00
35_E	108_E	2.319	1.00
103_D	207_Y	2.303	1.00
75_Q	79_A	2.240	1.00
26_N	209_P	2.222	1.00
40_D	67_Q	2.163	1.00
53_R	57_R	2.152	1.00
25_K	29_R	2.137	1.00
45_D	70_V	2.122	1.00
119_V	199_G	2.098	1.00
44_V	84_G	2.084	1.00
113_A	201_A	2.052	1.00
92_V	114_M	2.041	1.00
11_V	111_L	1.966	1.00
51_G	54_R	1.955	1.00
94_A	107_L	1.924	1.00
94_A	163_L	1.918	1.00
15_I	41_V	1.911	1.00
113_A	199_G	1.911	1.00
19_N	49_T	1.904	1.00
14_I	84_G	1.891	1.00
53_R	70_V	1.822	1.00
12_S	40_D	1.819	1.00
102_V	106_W	1.812	1.00
110_A	163_L	1.763	1.00
69_L	87_N	1.741	1.00
79_A	177_A	1.722	1.00
168_V	196_Y	1.719	1.00
53_R	68_L	1.718	1.00
26_N	101_T	1.717	1.00
15_I	27_T	1.716	1.00
120_D	165_R	1.708	1.00
10_H	91_D	1.685	1.00
127_E	207_Y	1.682	1.00
94_A	106_W	1.667	1.00
29_R	59_C	1.662	1.00
36_Y	111_L	1.659	1.00
71_E	83_T	1.642	1.00
25_K	58_N	1.629	1.00
21_S	55_R	1.618	1.00
43_V	56_V	1.608	1.00
105_D	109_T	1.595	1.00
86_Q	174_P	1.591	1.00
92_V	163_L	1.554	1.00
11_V	107_L	1.553	1.00
45_D	48_S	1.527	1.00
96_L	102_V	1.518	1.00
25_K	59_C	1.516	1.00
121_Y	198_Q	1.516	1.00
83_T	86_Q	1.494	1.00
10_H	38_G	1.486	1.00
40_D	90_S	1.477	1.00
120_D	196_Y	1.476	1.00
17_V	20_D	1.471	1.00
101_T	207_Y	1.470	1.00
72_D	75_Q	1.469	1.00
106_W	110_A	1.462	1.00
17_V	43_V	1.447	1.00
81_R	97_D	1.443	1.00
93_L	166_R	1.442	1.00
18_Y	74_V	1.435	1.00
69_L	83_T	1.431	1.00
110_A	124_C	1.385	1.00
36_Y	39_Y	1.384	1.00
88_A	166_R	1.382	1.00
25_K	55_R	1.370	1.00
67_Q	87_N	1.337	1.00
81_R	95_F	1.329	1.00
11_V	163_L	1.326	1.00
29_R	33_G	1.320	1.00
108_E	112_G	1.317	1.00
168_V	191_V	1.317	1.00
114_M	163_L	1.313	1.00
19_N	48_S	1.293	1.00
167_K	171_D	1.283	1.00
44_V	80_A	1.281	1.00
171_D	194_A	1.277	1.00
12_S	88_A	1.257	1.00
78_Y	183_G	1.256	1.00
57_R	60_A	1.248	1.00
57_R	70_V	1.246	1.00
72_D	83_T	1.242	1.00
176_D	186_E	1.241	1.00
28_L	41_V	1.237	1.00
162_L	188_G	1.229	1.00
85_V	95_F	1.228	1.00
85_V	169_F	1.221	1.00
129_T	207_Y	1.221	1.00
109_T	112_G	1.221	1.00
77_S	183_G	1.220	1.00
45_D	53_R	1.219	1.00
15_I	31_V	1.217	1.00
114_M	122_L	1.208	1.00
27_T	96_L	1.208	1.00
28_L	59_C	1.201	1.00
92_V	111_L	1.190	1.00
111_L	115_Q	1.186	1.00
31_V	96_L	1.185	1.00
40_D	89_E	1.172	1.00
72_D	79_A	1.171	1.00
127_E	204_A	1.161	1.00
94_A	102_V	1.159	1.00
91_D	165_R	1.159	1.00
121_Y	191_V	1.149	1.00
126_V	160_C	1.147	1.00
20_D	23_G	1.147	1.00
56_V	68_L	1.124	1.00
125_N	200_Y	1.123	1.00
39_Y	107_L	1.123	1.00
46_N	74_V	1.121	1.00
10_H	89_E	1.120	1.00
211_R	214_L	1.119	1.00
33_G	104_E	1.119	1.00
41_V	66_I	1.116	1.00
101_T	209_P	1.115	1.00
17_V	98_A	1.105	1.00
12_S	42_Y	1.103	1.00
109_T	201_A	1.098	1.00
10_H	90_S	1.087	1.00
77_S	81_R	1.084	1.00
171_D	196_Y	1.073	1.00
71_E	80_A	1.073	1.00
106_W	124_C	1.065	1.00
35_E	105_D	1.060	1.00
167_K	170_E	1.048	1.00
28_L	43_V	1.047	1.00
77_S	215_E	1.044	1.00
79_A	83_T	1.035	1.00
54_R	57_R	1.033	1.00
101_T	129_T	1.030	1.00
71_E	75_Q	1.030	1.00
32_V	66_I	1.026	1.00
105_D	108_E	1.016	1.00
118_D	197_E	1.014	1.00
169_F	187_F	1.001	1.00
112_G	116_E	0.999	1.00
85_V	93_L	0.998	1.00
165_R	168_V	0.983	1.00
13_C	94_A	0.981	1.00
124_C	205_T	0.973	1.00
30_S	102_V	0.970	1.00
45_D	71_E	0.969	1.00
110_A	122_L	0.966	1.00
113_A	116_E	0.965	1.00
16_P	80_A	0.964	1.00
130_C	134_T	0.957	1.00
58_N	62_E	0.943	1.00
113_A	122_L	0.939	1.00
67_Q	89_E	0.935	1.00
109_T	113_A	0.923	1.00
103_D	127_E	0.917	1.00
46_N	80_A	0.916	1.00
106_W	205_T	0.915	1.00
32_V	63_S	0.913	1.00
29_R	32_V	0.912	1.00
46_N	76_G	0.907	1.00
129_T	209_P	0.896	1.00
172_V	194_A	0.894	1.00
55_R	59_C	0.892	1.00
17_V	56_V	0.889	1.00
129_T	133_D	0.879	1.00
54_R	58_N	0.876	1.00
77_S	159_T	0.875	1.00
51_G	55_R	0.872	1.00
17_V	24_I	0.856	1.00
13_C	31_V	0.850	1.00
11_V	94_A	0.844	1.00
28_L	32_V	0.831	1.00
55_R	58_N	0.831	1.00
35_E	104_E	0.819	1.00
13_C	107_L	0.816	1.00
81_R	183_G	0.815	1.00
57_R	68_L	0.804	1.00
137_G	140_N	0.800	1.00
141_A	144_G	0.799	1.00
159_T	175_F	0.798	1.00
23_G	209_P	0.797	1.00
78_Y	82_K	0.796	1.00
227_G	230_Q	0.795	1.00
31_V	102_V	0.791	1.00
85_V	88_A	0.789	1.00
32_V	65_D	0.786	1.00
114_M	119_V	0.770	1.00
123_G	200_Y	0.770	1.00
27_T	30_S	0.769	1.00
77_S	80_A	0.767	1.00
30_S	101_T	0.765	1.00
20_D	211_R	0.760	1.00
29_R	62_E	0.759	1.00
60_A	66_I	0.758	1.00
120_D	197_E	0.756	1.00
91_D	115_Q	0.750	1.00
146_P	149_E	0.749	1.00
46_N	75_Q	0.745	1.00
60_A	68_L	0.744	1.00
42_Y	67_Q	0.733	1.00
58_N	61_A	0.730	1.00
9_A	115_Q	0.729	1.00
77_S	97_D	0.727	1.00
49_T	52_S	0.723	1.00
164_V	188_G	0.720	1.00
95_F	175_F	0.720	1.00
53_R	71_E	0.718	1.00
159_T	162_L	0.713	1.00
172_V	191_V	0.708	1.00
24_I	56_V	0.707	1.00
125_N	202_E	0.707	1.00
123_G	162_L	0.705	1.00
225_G	228_F	0.705	1.00
187_F	191_V	0.704	1.00
13_C	39_Y	0.703	1.00
9_A	91_D	0.698	1.00
80_A	83_T	0.698	1.00
130_C	133_D	0.694	1.00
109_T	205_T	0.691	1.00
176_D	190_R	0.691	1.00
110_A	114_M	0.686	1.00
44_V	83_T	0.685	1.00
10_H	40_D	0.683	1.00
75_Q	80_A	0.683	1.00
32_V	59_C	0.683	1.00
14_I	44_V	0.680	1.00
103_D	106_W	0.676	1.00
168_V	172_V	0.676	1.00
31_V	41_V	0.674	1.00
128_L	210_A	0.674	1.00
103_D	205_T	0.673	1.00
42_Y	87_N	0.670	1.00
82_K	175_F	0.670	1.00
214_L	217_L	0.669	1.00
120_D	168_V	0.667	1.00
42_Y	84_G	0.665	1.00
47_G	72_D	0.664	1.00
164_V	187_F	0.662	1.00
57_R	61_A	0.660	1.00
17_V	45_D	0.660	1.00
91_D	167_K	0.657	1.00
53_R	56_V	0.654	1.00
88_A	93_L	0.652	1.00
160_C	206_V	0.651	1.00
82_K	174_P	0.651	1.00
168_V	171_D	0.647	1.00
10_H	36_Y	0.646	1.00
169_F	174_P	0.643	1.00
19_N	50_D	0.643	1.00
226_R	230_Q	0.641	1.00
63_S	66_I	0.641	1.00
174_P	187_F	0.637	1.00
223_R	227_G	0.636	1.00
75_Q	83_T	0.633	1.00
164_V	191_V	0.630	1.00
36_Y	107_L	0.630	1.00
12_S	166_R	0.626	1.00
124_C	161_A	0.624	1.00
10_H	39_Y	0.624	1.00
21_S	25_K	0.623	1.00
182_G	185_R	0.623	1.00
82_K	177_A	0.621	1.00
24_I	98_A	0.621	1.00
68_L	71_E	0.618	1.00
153_D	197_E	0.617	1.00
201_A	204_A	0.616	1.00
85_V	174_P	0.613	1.00
229_C	233_R	0.612	1.00
220_K	224_V	0.610	1.00
43_V	66_I	0.610	1.00
52_S	55_R	0.609	1.00
221_N	224_V	0.605	1.00
111_L	163_L	0.603	1.00
82_K	86_Q	0.602	1.00
168_V	195_G	0.601	1.00
117_Q	199_G	0.597	1.00
34_Q	107_L	0.596	1.00
100_E	206_V	0.596	1.00
71_E	79_A	0.596	1.00
27_T	31_V	0.595	1.00
42_Y	88_A	0.592	1.00
16_P	98_A	0.590	1.00
113_A	119_V	0.589	1.00
21_S	50_D	0.586	1.00
210_A	217_L	0.585	1.00
125_N	204_A	0.582	1.00
131_P	134_T	0.580	1.00
34_Q	108_E	0.579	1.00
123_G	157_A	0.577	1.00
120_D	195_G	0.575	1.00
102_V	107_L	0.574	1.00
94_A	161_A	0.572	1.00
164_V	169_F	0.569	1.00
75_Q	177_A	0.568	1.00
147_V	151_L	0.568	1.00
24_I	52_S	0.566	1.00
247_T	250_G	0.563	1.00
140_N	143_T	0.563	1.00
112_G	115_Q	0.562	1.00
59_C	63_S	0.561	1.00
34_Q	102_V	0.560	1.00
161_A	206_V	0.558	1.00
15_I	28_L	0.557	1.00
97_D	183_G	0.556	1.00
114_M	165_R	0.554	1.00
16_P	81_R	0.554	1.00
231_K	235_Y	0.553	1.00
27_T	100_E	0.551	1.00
119_V	165_R	0.548	1.00
117_Q	120_D	0.548	1.00
152_E	155_N	0.546	1.00
16_P	46_N	0.545	1.00
92_V	165_R	0.545	1.00
105_D	203_N	0.544	1.00
192_H	198_Q	0.543	1.00
122_L	163_L	0.543	1.00
170_E	174_P	0.543	1.00
135_L	139_Y	0.542	1.00
96_L	206_V	0.538	1.00
118_D	165_R	0.538	1.00
146_P	151_L	0.536	1.00
23_G	211_R	0.536	1.00
15_I	43_V	0.535	1.00
237_E	240_G	0.531	1.00
25_K	62_E	0.531	1.00
84_G	88_A	0.528	1.00
27_T	98_A	0.528	1.00
15_I	96_L	0.528	1.00
176_D	234_Y	0.527	1.00
9_A	36_Y	0.526	1.00
56_V	60_A	0.526	1.00
143_T	146_P	0.525	1.00
24_I	55_R	0.524	1.00
10_H	115_Q	0.523	1.00
224_V	228_F	0.523	1.00
157_A	162_L	0.522	1.00
111_L	114_M	0.522	1.00
185_R	189_D	0.521	1.00
14_I	88_A	0.521	1.00
21_S	52_S	0.520	1.00
59_C	62_E	0.520	1.00
222_F	226_R	0.519	1.00
47_G	74_V	0.517	1.00
93_L	169_F	0.516	1.00
31_V	34_Q	0.516	1.00
39_Y	89_E	0.515	1.00
57_R	71_E	0.513	1.00
120_D	123_G	0.511	1.00
119_V	122_L	0.509	1.00
193_D	238_R	0.508	1.00
232_Q	236_P	0.508	1.00
26_N	29_R	0.508	1.00
11_V	36_Y	0.507	1.00
126_V	161_A	0.507	1.00
23_G	27_T	0.505	1.00
141_A	145_F	0.504	1.00
237_E	241_K	0.502	1.00
245_P	249_S	0.502	1.00
215_E	218_A	0.501	1.00
113_A	117_Q	0.500	1.00

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
3bcvA	2	0.5828	100	0.344	Contact Map
2d7iA	1	1	100	0.352	Contact Map
1xhbA	1	0.9603	100	0.353	Contact Map
2z86A	2	0.8444	100	0.356	Contact Map
3l7iA	4	0	100	0.359	Contact Map
1qg8A	1	0.7285	100	0.361	Contact Map
5ajoA	1	0.9868	100	0.368	Contact Map
4fixA	3	0.9967	100	0.431	Contact Map
4p02A	1	0.9404	100	0.453	Contact Map
2bo4A	4	0.9172	100	0.456	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.0094 seconds.