Q9HQN5 - HALSA - GREMLIN Contacts

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Q9HQN5 - Glycine betaine transporter

UniProt:	Q9HQN5	Sequences: MSRRVWYLLGLEDATWPERALFAVTMAAMLALAVAGFRRPTQLSTVLNGAFDWVLRYFGWWFILLGFVLLVLVLGVTWSRYGRLRIGGPDAEPEFDTFSWLSMVFTVGFGASILIWGVGEPVSIVQQPPPEPWPVGGASAKSLALAFMFVHEVFPGLAMWYLPVALAFGIIVYTRGIGEYKVSTMLAGIMPAGDHPVVLWAVDVAAIIATIGGIATTLGFSSQTMAAILGGVFGLQSAWLTYGIFAAIGAVFLVDVWLGLRSGIRNAARATMLLIGVAMAVLVVVGPTLFTFQLGLDATGVWLNNVVRLMLYTDPTAAGHWAANWTGFWWAWWAAWSIFVGSFVARVSKGRTVREMFIVLVVAPGVLSWVQHTLIGGWVLAPDYVGPVGNALSANGIPAAIARALSITPYGSVLALLFVLVIAGYIITSLDSAVFMIAAITLGDEDPNPRNRACWGLLLAAFGVMSLELSSFEAIEALSPVLALPFTLFLLVIVYASYVAAREYARDRDDVAVSPGGLLSSRSSASDTDPEAGSGTDAAPTGDD	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	544 (490)
Sequences:	3388 (2076)
Seq/√Len:	93.8

ECOLI - BETT CAIT YEAV
BACSU - OPUD
HALSA - Q9HQN5

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
85_R	92_E	4.568	1.00
207_I	441_T	3.776	1.00
88_G	91_A	3.534	1.00
61_W	487_T	3.487	1.00
281_V	414_L	3.383	1.00
281_V	285_V	3.307	1.00
34_V	38_R	3.298	1.00
91_A	349_K	3.092	1.00
137_G	140_A	3.043	1.00
383_D	389_G	2.959	1.00
242_Y	464_V	2.852	1.00
26_M	454_C	2.732	1.00
381_A	385_V	2.686	1.00
255_D	431_D	2.586	1.00
24_V	204_V	2.585	1.00
239_W	243_G	2.533	1.00
378_W	408_T	2.518	1.00
39_R	42_Q	2.496	1.00
295_G	373_T	2.491	1.00
186_L	202_V	2.465	1.00
125_V	384_Y	2.462	1.00
279_M	374_L	2.399	1.00
66_G	159_M	2.373	1.00
72_L	494_V	2.352	1.00
283_V	374_L	2.348	1.00
54_V	484_L	2.334	1.00
353_V	501_A	2.313	1.00
35_A	42_Q	2.307	1.00
95_F	261_R	2.305	1.00
77_T	357_F	2.297	1.00
258_L	266_N	2.291	1.00
282_L	408_T	2.285	1.00
68_V	491_L	2.278	1.00
283_V	292_F	2.267	1.00
99_S	269_R	2.232	1.00
190_M	194_D	2.205	1.00
77_T	358_I	2.154	1.00
254_V	258_L	2.152	1.00
249_G	460_A	2.150	1.00
430_L	459_L	2.122	1.00
149_F	369_W	2.109	1.00
423_A	427_I	2.108	1.00
75_G	498_Y	2.091	1.00
88_G	176_G	2.087	1.00
72_L	498_Y	2.070	1.00
192_A	195_H	2.062	1.00
50_A	53_W	2.061	1.00
257_W	453_A	2.030	1.00
226_A	244_I	2.019	1.00
403_R	406_S	2.004	1.00
226_A	237_S	1.972	1.00
253_L	257_W	1.946	1.00
294_L	377_G	1.934	1.00
484_L	488_L	1.934	1.00
37_F	465_M	1.906	1.00
96_D	99_S	1.883	1.00
122_V	383_D	1.863	1.00
187_A	195_H	1.857	1.00
65_L	69_L	1.852	1.00
197_V	201_A	1.834	1.00
177_I	187_A	1.834	1.00
80_R	83_R	1.833	1.00
50_A	481_V	1.829	1.00
190_M	198_V	1.799	1.00
275_I	425_Y	1.794	1.00
67_F	311_L	1.790	1.00
81_Y	502_R	1.789	1.00
69_L	490_L	1.789	1.00
295_G	370_V	1.787	1.00
196_P	199_L	1.786	1.00
428_T	432_S	1.784	1.00
405_L	418_F	1.771	1.00
273_L	277_V	1.764	1.00
253_L	456_G	1.761	1.00
71_V	75_G	1.754	1.00
102_S	106_T	1.746	1.00
243_G	247_A	1.742	1.00
430_L	434_V	1.738	1.00
488_L	492_V	1.734	1.00
320_H	324_N	1.733	1.00
434_V	456_G	1.713	1.00
226_A	240_L	1.713	1.00
20_A	200_W	1.709	1.00
304_N	308_R	1.707	1.00
65_L	487_T	1.702	1.00
335_A	479_S	1.691	1.00
185_M	493_I	1.676	1.00
405_L	414_L	1.665	1.00
20_A	24_V	1.661	1.00
226_A	241_T	1.660	1.00
287_P	291_T	1.658	1.00
246_A	464_V	1.649	1.00
442_L	445_E	1.646	1.00
297_D	315_P	1.642	1.00
116_W	119_G	1.638	1.00
106_T	424_G	1.629	1.00
85_R	90_D	1.623	1.00
79_S	82_G	1.619	1.00
283_V	288_T	1.619	1.00
305_N	308_R	1.581	1.00
35_A	43_L	1.573	1.00
116_W	397_I	1.558	1.00
156_G	333_W	1.553	1.00
68_V	494_V	1.547	1.00
64_L	296_L	1.543	1.00
230_G	237_S	1.542	1.00
295_G	369_W	1.534	1.00
91_A	174_T	1.530	1.00
183_S	200_W	1.519	1.00
382_P	407_I	1.518	1.00
153_V	365_G	1.517	1.00
230_G	236_Q	1.515	1.00
205_A	489_F	1.510	1.00
438_A	451_N	1.509	1.00
82_G	354_R	1.508	1.00
75_G	79_S	1.495	1.00
97_T	355_E	1.494	1.00
125_V	136_G	1.475	1.00
135_V	140_A	1.471	1.00
235_L	240_L	1.463	1.00
270_A	273_L	1.462	1.00
69_L	494_V	1.450	1.00
88_G	174_T	1.431	0.99
401_I	418_F	1.430	0.99
32_L	212_G	1.425	0.99
386_G	389_G	1.422	0.99
266_N	270_A	1.418	0.99
70_L	74_L	1.416	0.99
276_G	280_A	1.412	0.99
76_V	353_V	1.412	0.99
410_Y	413_V	1.402	0.99
491_L	495_Y	1.397	0.99
190_M	492_V	1.394	0.99
413_V	416_L	1.387	0.99
253_L	453_A	1.381	0.99
166_L	353_V	1.378	0.99
141_K	384_Y	1.374	0.99
187_A	192_A	1.371	0.99
250_A	254_V	1.370	0.99
46_V	50_A	1.368	0.99
175_R	500_A	1.362	0.99
229_L	240_L	1.354	0.99
189_I	495_Y	1.349	0.99
146_A	305_N	1.348	0.99
236_Q	240_L	1.342	0.99
99_S	265_R	1.340	0.99
222_S	244_I	1.332	0.99
171_I	500_A	1.330	0.99
177_I	194_D	1.323	0.99
70_L	306_V	1.311	0.99
29_M	211_I	1.309	0.99
48_N	52_D	1.305	0.99
378_W	404_A	1.304	0.99
35_A	39_R	1.304	0.99
53_W	57_Y	1.301	0.99
265_R	269_R	1.300	0.99
220_F	328_F	1.292	0.99
365_G	369_W	1.292	0.99
42_Q	46_V	1.287	0.99
67_F	155_P	1.287	0.99
457_L	461_A	1.285	0.99
128_P	131_E	1.283	0.99
78_W	358_I	1.280	0.99
421_V	424_G	1.273	0.99
298_A	373_T	1.269	0.99
483_A	487_T	1.266	0.99
146_A	301_V	1.265	0.99
146_A	309_L	1.265	0.99
164_V	493_I	1.259	0.99
36_G	43_L	1.257	0.99
161_Y	333_W	1.257	0.99
191_P	196_P	1.248	0.99
78_W	354_R	1.248	0.99
23_A	27_A	1.247	0.99
473_E	476_E	1.233	0.98
69_L	163_P	1.216	0.98
197_V	200_W	1.213	0.98
246_A	250_A	1.213	0.98
434_V	459_L	1.212	0.98
449_P	452_R	1.207	0.98
258_L	262_S	1.192	0.98
270_A	424_G	1.191	0.98
62_F	331_A	1.191	0.98
296_L	300_G	1.190	0.98
240_L	243_G	1.188	0.98
429_S	432_S	1.181	0.98
27_A	31_A	1.179	0.98
18_E	200_W	1.176	0.98
98_F	102_S	1.175	0.98
89_P	174_T	1.174	0.98
45_T	49_G	1.171	0.98
98_F	272_M	1.171	0.98
94_E	261_R	1.169	0.98
303_L	307_V	1.167	0.98
248_I	423_A	1.157	0.98
187_A	194_D	1.156	0.98
31_A	35_A	1.156	0.98
155_P	310_M	1.151	0.98
257_W	449_P	1.151	0.98
231_G	406_S	1.147	0.98
454_C	458_L	1.140	0.97
70_L	158_A	1.137	0.97
498_Y	502_R	1.135	0.97
67_F	310_M	1.134	0.97
84_L	501_A	1.133	0.97
287_P	381_A	1.126	0.97
307_V	310_M	1.125	0.97
52_D	56_R	1.124	0.97
167_A	493_I	1.123	0.97
291_T	374_L	1.123	0.97
70_L	154_F	1.122	0.97
128_P	135_V	1.122	0.97
247_A	251_V	1.120	0.97
95_F	346_R	1.114	0.97
109_F	368_S	1.106	0.97
466_S	478_L	1.102	0.97
19_R	23_A	1.098	0.97
46_V	49_G	1.095	0.97
337_S	490_L	1.094	0.97
155_P	302_W	1.093	0.97
142_S	297_D	1.084	0.97
85_R	352_T	1.080	0.96
109_F	156_G	1.080	0.96
403_R	407_I	1.075	0.96
226_A	236_Q	1.072	0.96
256_V	260_L	1.064	0.96
366_V	370_V	1.063	0.96
383_D	386_G	1.061	0.96
43_L	47_L	1.061	0.96
167_A	497_S	1.061	0.96
81_Y	498_Y	1.055	0.96
183_S	252_F	1.055	0.96
205_A	482_L	1.051	0.96
362_V	366_V	1.049	0.96
198_V	201_A	1.047	0.96
115_I	398_P	1.046	0.96
61_W	65_L	1.046	0.96
336_W	429_S	1.042	0.96
299_T	369_W	1.042	0.96
267_A	431_D	1.042	0.96
191_P	199_L	1.040	0.96
57_Y	289_L	1.038	0.96
172_V	180_Y	1.036	0.96
177_I	184_T	1.026	0.95
408_T	413_V	1.026	0.95
214_I	264_I	1.025	0.95
70_L	155_P	1.025	0.95
292_F	296_L	1.017	0.95
228_I	402_A	1.014	0.95
118_V	400_A	1.012	0.95
41_T	45_T	1.011	0.95
256_V	456_G	1.010	0.95
294_L	298_A	1.009	0.95
139_S	143_L	1.009	0.95
188_G	191_P	1.008	0.95
412_S	416_L	1.007	0.95
280_A	284_V	1.003	0.95
290_F	384_Y	1.000	0.95
162_L	360_L	1.000	0.95
53_W	58_F	0.998	0.94
59_G	327_G	0.997	0.94
102_S	272_M	0.996	0.94
184_T	187_A	0.996	0.94
101_L	363_A	0.995	0.94
193_G	196_P	0.991	0.94
383_D	388_V	0.986	0.94
251_V	427_I	0.983	0.94
399_A	403_R	0.982	0.94
252_F	456_G	0.975	0.94
226_A	238_A	0.973	0.94
229_L	233_F	0.961	0.93
41_T	44_S	0.957	0.93
390_N	394_A	0.954	0.93
44_S	48_N	0.953	0.93
393_S	396_G	0.951	0.93
79_S	84_L	0.951	0.93
147_F	309_L	0.950	0.93
132_P	135_V	0.948	0.93
293_Q	313_T	0.946	0.93
74_L	78_W	0.942	0.93
391_A	395_N	0.939	0.92
117_G	372_H	0.938	0.92
95_F	99_S	0.937	0.92
109_F	113_I	0.935	0.92
97_T	101_L	0.934	0.92
245_F	463_G	0.931	0.92
28_A	208_I	0.931	0.92
262_S	266_N	0.930	0.92
116_W	220_F	0.924	0.92
486_F	489_F	0.923	0.92
154_F	361_V	0.923	0.92
77_T	82_G	0.923	0.92
214_I	433_A	0.918	0.92
216_T	476_E	0.914	0.91
139_S	142_S	0.913	0.91
383_D	387_P	0.911	0.91
67_F	307_V	0.909	0.91
242_Y	246_A	0.906	0.91
190_M	496_A	0.905	0.91
151_H	326_T	0.905	0.91
175_R	504_Y	0.903	0.91
95_F	103_M	0.903	0.91
344_V	360_L	0.903	0.91
416_L	420_L	0.897	0.91
119_G	321_W	0.894	0.91
249_G	252_F	0.893	0.90
65_L	491_L	0.891	0.90
145_L	298_A	0.891	0.90
497_S	501_A	0.889	0.90
33_A	465_M	0.887	0.90
124_I	321_W	0.885	0.90
194_D	199_L	0.885	0.90
298_A	301_V	0.884	0.90
165_A	356_M	0.884	0.90
453_A	457_L	0.882	0.90
251_V	254_V	0.881	0.90
425_Y	429_S	0.877	0.90
437_I	459_L	0.877	0.90
231_G	399_A	0.873	0.89
304_N	307_V	0.872	0.89
217_T	221_S	0.870	0.89
189_I	198_V	0.869	0.89
76_V	166_L	0.868	0.89
130_P	143_L	0.868	0.89
111_A	217_T	0.866	0.89
136_G	140_A	0.862	0.89
170_I	504_Y	0.862	0.89
119_G	397_I	0.861	0.89
20_A	23_A	0.861	0.89
373_T	378_W	0.860	0.89
230_G	235_L	0.859	0.89
216_T	475_I	0.857	0.89
246_A	457_L	0.857	0.89
180_Y	183_S	0.856	0.89
71_V	306_V	0.856	0.89
298_A	377_G	0.853	0.88
242_Y	468_E	0.848	0.88
154_F	158_A	0.848	0.88
72_L	163_P	0.846	0.88
118_V	404_A	0.840	0.88
392_L	396_G	0.838	0.87
441_T	451_N	0.836	0.87
260_L	435_F	0.835	0.87
104_V	429_S	0.835	0.87
33_A	461_A	0.834	0.87
61_W	488_L	0.831	0.87
153_V	156_G	0.831	0.87
267_A	424_G	0.829	0.87
266_N	269_R	0.827	0.87
330_W	333_W	0.826	0.87
300_G	311_L	0.823	0.87
111_A	426_I	0.823	0.87
67_F	306_V	0.821	0.86
411_G	415_A	0.821	0.86
256_V	452_R	0.820	0.86
269_R	431_D	0.820	0.86
297_D	301_V	0.819	0.86
360_L	363_A	0.818	0.86
264_I	447_P	0.818	0.86
187_A	193_G	0.814	0.86
136_G	139_S	0.813	0.86
216_T	466_S	0.807	0.85
285_V	414_L	0.806	0.85
385_V	389_G	0.805	0.85
171_I	177_I	0.804	0.85
175_R	503_E	0.801	0.85
111_A	221_S	0.800	0.85
63_I	322_A	0.800	0.85
20_A	204_V	0.798	0.85
118_V	122_V	0.796	0.85
285_V	408_T	0.795	0.85
106_T	268_A	0.793	0.84
281_V	410_Y	0.792	0.84
141_K	316_T	0.790	0.84
128_P	132_P	0.787	0.84
99_S	102_S	0.786	0.84
145_L	149_F	0.783	0.84
50_A	54_V	0.782	0.84
25_T	207_I	0.781	0.84
288_T	291_T	0.781	0.84
45_T	48_N	0.776	0.83
218_L	426_I	0.776	0.83
63_I	150_V	0.776	0.83
258_L	261_R	0.775	0.83
35_A	46_V	0.775	0.83
410_Y	414_L	0.774	0.83
80_R	374_L	0.774	0.83
66_G	155_P	0.773	0.83
26_M	458_L	0.773	0.83
300_G	313_T	0.772	0.83
58_F	484_L	0.772	0.83
112_S	152_E	0.769	0.83
392_L	395_N	0.768	0.82
125_V	137_G	0.768	0.82
276_G	367_L	0.765	0.82
60_W	64_L	0.762	0.82
362_V	365_G	0.761	0.82
59_G	293_Q	0.761	0.82
113_I	217_T	0.760	0.82
126_Q	136_G	0.759	0.82
277_V	413_V	0.759	0.82
305_N	309_L	0.758	0.82
107_V	340_V	0.758	0.82
84_L	170_I	0.755	0.81
149_F	298_A	0.753	0.81
255_D	268_A	0.751	0.81
291_T	378_W	0.748	0.81
249_G	426_I	0.748	0.81
227_A	237_S	0.745	0.81
189_I	496_A	0.741	0.80
117_G	371_Q	0.740	0.80
54_V	481_V	0.739	0.80
459_L	463_G	0.738	0.80
158_A	162_L	0.737	0.80
211_I	437_I	0.737	0.80
406_S	411_G	0.736	0.80
499_V	503_E	0.736	0.80
290_F	381_A	0.734	0.80
62_F	327_G	0.734	0.80
131_E	135_V	0.734	0.80
85_R	355_E	0.731	0.79
51_F	55_L	0.729	0.79
94_E	349_K	0.729	0.79
256_V	434_V	0.729	0.79
62_F	484_L	0.728	0.79
255_D	267_A	0.727	0.79
434_V	438_A	0.727	0.79
290_F	377_G	0.726	0.79
165_A	306_V	0.725	0.79
239_W	242_Y	0.723	0.79
396_G	399_A	0.720	0.78
153_V	369_W	0.718	0.78
271_T	428_T	0.718	0.78
73_V	361_V	0.717	0.78
291_T	370_V	0.717	0.78
239_W	246_A	0.715	0.78
61_W	491_L	0.712	0.77
232_V	416_L	0.711	0.77
261_R	266_N	0.711	0.77
131_E	143_L	0.711	0.77
33_A	462_F	0.711	0.77
410_Y	416_L	0.710	0.77
282_L	378_W	0.710	0.77
109_F	155_P	0.710	0.77
178_G	184_T	0.709	0.77
245_F	426_I	0.708	0.77
138_A	384_Y	0.707	0.77
148_M	372_H	0.706	0.77
334_A	489_F	0.705	0.77
183_S	433_A	0.703	0.77
411_G	416_L	0.702	0.76
229_L	235_L	0.701	0.76
164_V	337_S	0.700	0.76
253_L	457_L	0.700	0.76
205_A	481_V	0.699	0.76
292_F	374_L	0.699	0.76
132_P	143_L	0.698	0.76
131_E	140_A	0.696	0.76
29_M	458_L	0.692	0.75
405_L	415_A	0.692	0.75
151_H	330_W	0.691	0.75
66_G	165_A	0.691	0.75
499_V	502_R	0.690	0.75
157_L	348_S	0.690	0.75
480_P	483_A	0.690	0.75
339_F	433_A	0.689	0.75
119_G	122_V	0.688	0.75
186_L	492_V	0.687	0.75
326_T	330_W	0.685	0.75
75_G	78_W	0.685	0.75
290_F	294_L	0.677	0.74
458_L	461_A	0.677	0.74
73_V	161_Y	0.676	0.74
435_F	452_R	0.675	0.74
277_V	281_V	0.673	0.73
220_F	473_E	0.673	0.73
314_D	320_H	0.673	0.73
89_P	508_R	0.673	0.73
158_A	361_V	0.672	0.73
79_S	357_F	0.672	0.73
382_P	404_A	0.671	0.73
289_L	292_F	0.670	0.73
200_W	204_V	0.669	0.73
237_S	240_L	0.667	0.73
132_P	137_G	0.666	0.73
162_L	357_F	0.666	0.73
51_F	477_A	0.665	0.73
268_A	431_D	0.663	0.72
256_V	430_L	0.659	0.72
49_G	53_W	0.658	0.72
218_L	221_S	0.656	0.72
223_Q	241_T	0.654	0.71
72_L	76_V	0.653	0.71
306_V	310_M	0.653	0.71
356_M	364_P	0.651	0.71
392_L	403_R	0.650	0.71
252_F	438_A	0.648	0.71
186_L	209_A	0.647	0.70
252_F	433_A	0.647	0.70
38_R	503_E	0.646	0.70
404_A	408_T	0.646	0.70
281_V	405_L	0.645	0.70
53_W	56_R	0.645	0.70
339_F	429_S	0.645	0.70
163_P	494_V	0.645	0.70
122_V	400_A	0.645	0.70
103_M	106_T	0.643	0.70
249_G	459_L	0.643	0.70
469_L	472_F	0.643	0.70
255_D	271_T	0.643	0.70
232_V	415_A	0.642	0.70
91_A	94_E	0.642	0.70
300_G	303_L	0.641	0.70
378_W	381_A	0.640	0.70
221_S	224_T	0.639	0.70
172_V	176_G	0.638	0.69
123_S	127_Q	0.637	0.69
439_A	447_P	0.633	0.69
173_Y	375_I	0.633	0.69
178_G	187_A	0.631	0.69
103_M	347_V	0.629	0.68
253_L	460_A	0.629	0.68
186_L	199_L	0.628	0.68
378_W	427_I	0.627	0.68
127_Q	135_V	0.627	0.68
226_A	230_G	0.627	0.68
303_L	306_V	0.627	0.68
108_G	341_G	0.625	0.68
230_G	233_F	0.625	0.68
101_L	367_L	0.624	0.68
27_A	30_L	0.623	0.68
95_F	260_L	0.621	0.67
156_G	479_S	0.618	0.67
32_L	43_L	0.617	0.67
188_G	203_D	0.616	0.67
74_L	361_V	0.616	0.67
503_E	506_R	0.615	0.67
382_P	388_V	0.615	0.67
116_W	400_A	0.614	0.66
170_I	497_S	0.614	0.66
219_G	328_F	0.613	0.66
355_E	358_I	0.612	0.66
411_G	414_L	0.612	0.66
291_T	377_G	0.609	0.66
120_E	325_W	0.608	0.66
36_G	47_L	0.608	0.66
145_L	294_L	0.605	0.65
36_G	181_K	0.605	0.65
155_P	306_V	0.603	0.65
118_V	379_V	0.602	0.65
169_G	356_M	0.602	0.65
156_G	368_S	0.599	0.65
269_R	273_L	0.599	0.65
211_I	459_L	0.598	0.64
109_F	333_W	0.598	0.64
104_V	344_V	0.596	0.64
109_F	329_W	0.595	0.64
158_A	163_P	0.595	0.64
245_F	464_V	0.595	0.64
321_W	371_Q	0.595	0.64
96_D	102_S	0.595	0.64
314_D	317_A	0.594	0.64
262_S	265_R	0.594	0.64
157_L	425_Y	0.594	0.64
128_P	140_A	0.593	0.64
141_K	290_F	0.593	0.64
246_A	416_L	0.592	0.64
63_I	67_F	0.592	0.64
170_I	353_V	0.591	0.64
264_I	432_S	0.590	0.63
100_W	359_V	0.590	0.63
104_V	108_G	0.588	0.63
22_F	451_N	0.588	0.63
123_S	397_I	0.587	0.63
300_G	315_P	0.587	0.63
36_G	469_L	0.586	0.63
177_I	195_H	0.586	0.63
188_G	199_L	0.586	0.63
282_L	382_P	0.585	0.63
27_A	46_V	0.585	0.63
232_V	422_I	0.585	0.63
235_L	243_G	0.584	0.63
449_P	456_G	0.584	0.63
252_F	256_V	0.582	0.62
293_Q	296_L	0.581	0.62
231_G	411_G	0.581	0.62
23_A	26_M	0.580	0.62
24_V	27_A	0.579	0.62
167_A	334_A	0.579	0.62
76_V	501_A	0.578	0.62
252_F	460_A	0.578	0.62
379_V	404_A	0.577	0.62
239_W	413_V	0.574	0.61
188_G	196_P	0.574	0.61
279_M	367_L	0.574	0.61
110_G	113_I	0.572	0.61
206_A	215_A	0.572	0.61
271_T	425_Y	0.571	0.61
98_F	362_V	0.571	0.61
502_R	506_R	0.569	0.61
73_V	163_P	0.568	0.61
165_A	170_I	0.567	0.60
31_A	34_V	0.567	0.60
222_S	245_F	0.566	0.60
216_T	479_S	0.565	0.60
466_S	472_F	0.565	0.60
201_A	503_E	0.565	0.60
430_L	437_I	0.565	0.60
207_I	437_I	0.564	0.60
156_G	161_Y	0.564	0.60
346_R	452_R	0.563	0.60
36_G	465_M	0.563	0.60
209_A	456_G	0.563	0.60
258_L	430_L	0.563	0.60
283_V	291_T	0.560	0.59
73_V	357_F	0.560	0.59
63_I	114_L	0.560	0.59
59_G	409_P	0.558	0.59
102_S	269_R	0.557	0.59
502_R	505_A	0.557	0.59
189_I	196_P	0.557	0.59
94_E	346_R	0.556	0.59
477_A	480_P	0.556	0.59
395_N	403_R	0.555	0.59
153_V	157_L	0.555	0.59
496_A	499_V	0.555	0.59
192_A	196_P	0.554	0.59
120_E	152_E	0.554	0.59
181_K	256_V	0.554	0.59
296_L	311_L	0.554	0.59
112_S	333_W	0.553	0.58
135_V	139_S	0.552	0.58
191_P	194_D	0.552	0.58
209_A	335_A	0.552	0.58
91_A	95_F	0.550	0.58
336_W	340_V	0.550	0.58
393_S	398_P	0.550	0.58
284_V	292_F	0.549	0.58
159_M	490_L	0.548	0.58
75_G	83_R	0.548	0.58
458_L	462_F	0.547	0.58
336_W	339_F	0.546	0.58
319_G	322_A	0.545	0.57
101_L	359_V	0.545	0.57
104_V	432_S	0.544	0.57
501_A	505_A	0.544	0.57
116_W	312_Y	0.543	0.57
252_F	459_L	0.543	0.57
17_P	22_F	0.542	0.57
244_I	298_A	0.542	0.57
248_I	251_V	0.542	0.57
86_I	170_I	0.541	0.57
435_F	439_A	0.541	0.57
279_M	283_V	0.541	0.57
225_M	423_A	0.541	0.57
174_T	349_K	0.541	0.57
349_K	457_L	0.540	0.57
168_F	342_S	0.540	0.57
194_D	197_V	0.540	0.57
47_L	481_V	0.539	0.57
235_L	238_A	0.539	0.57
233_F	416_L	0.539	0.57
64_L	68_V	0.538	0.56
67_F	71_V	0.537	0.56
291_T	373_T	0.537	0.56
37_F	420_L	0.536	0.56
155_P	159_M	0.536	0.56
232_V	344_V	0.536	0.56
121_P	463_G	0.535	0.56
55_L	323_A	0.535	0.56
210_T	330_W	0.535	0.56
492_V	495_Y	0.534	0.56
182_V	486_F	0.534	0.56
377_G	381_A	0.533	0.56
238_A	241_T	0.532	0.56
147_F	331_A	0.531	0.55
51_F	54_V	0.531	0.55
459_L	479_S	0.530	0.55
391_A	394_A	0.530	0.55
57_Y	61_W	0.529	0.55
85_R	91_A	0.529	0.55
401_I	422_I	0.525	0.55
501_A	504_Y	0.525	0.55
487_T	491_L	0.524	0.54
107_V	217_T	0.524	0.54
174_T	504_Y	0.523	0.54
281_V	367_L	0.523	0.54
90_D	175_R	0.523	0.54
461_A	465_M	0.523	0.54
503_E	507_D	0.523	0.54
488_L	491_L	0.523	0.54
283_V	419_V	0.522	0.54
109_F	436_M	0.522	0.54
332_W	476_E	0.522	0.54
164_V	347_V	0.522	0.54
259_G	431_D	0.521	0.54
277_V	280_A	0.521	0.54
70_L	361_V	0.520	0.54
22_F	129_P	0.519	0.54
441_T	455_W	0.519	0.54
201_A	204_V	0.517	0.54
56_R	324_N	0.516	0.53
99_S	266_N	0.515	0.53
59_G	128_P	0.515	0.53
334_A	490_L	0.515	0.53
212_G	436_M	0.514	0.53
125_V	141_K	0.514	0.53
494_V	498_Y	0.514	0.53
57_Y	262_S	0.514	0.53
282_L	285_V	0.514	0.53
328_F	478_L	0.514	0.53
386_G	391_A	0.513	0.53
182_V	206_A	0.512	0.53
401_I	405_L	0.512	0.53
121_P	206_A	0.512	0.53
473_E	477_A	0.511	0.53
66_G	156_G	0.509	0.52
169_G	173_Y	0.508	0.52
117_G	501_A	0.507	0.52
278_A	418_F	0.507	0.52
129_P	147_F	0.507	0.52
78_W	458_L	0.507	0.52
378_W	382_P	0.507	0.52
397_I	404_A	0.506	0.52
370_V	374_L	0.506	0.52
225_M	248_I	0.506	0.52
449_P	453_A	0.506	0.52
142_S	301_V	0.505	0.52
77_T	80_R	0.505	0.52
81_Y	501_A	0.504	0.52
382_P	387_P	0.504	0.52
418_F	422_I	0.502	0.51
285_V	410_Y	0.501	0.51
253_L	437_I	0.501	0.51
337_S	438_A	0.500	0.51

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
4c7rA	3	0.9467	100	0.081	Contact Map
2wswA	3	0.9191	100	0.104	Contact Map
2xq2A	2	0.7721	96.9	0.961	Contact Map
3l1lA	2	0.682	96	0.964	Contact Map
3dh4A	3	0.7298	95.4	0.966	Contact Map
3giaA	1	0.682	95.4	0.966	Contact Map
2jlnA	1	0.6893	95.3	0.966	Contact Map
4djkA	2	0.6305	92.5	0.97	Contact Map
4pypA	1	0.704	89.9	0.972	Contact Map
3pjsK	4	0.2408	65.6	0.978	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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