GREMLIN Database
Q9HQN1 - Sulfite oxidase homolog
UniProt: Q9HQN1 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 198 (176)
Sequences: 4208 (2423)
Seq/√Len: 182.6

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
68_T135_W3.7301.00
59_S62_E3.3511.00
53_D101_G3.2171.00
92_P95_E3.2031.00
70_T89_T3.1351.00
49_T170_E3.1061.00
49_T168_G2.9471.00
53_D103_T2.8991.00
111_F169_V2.6421.00
66_L99_A2.6231.00
112_H168_G2.5741.00
89_T136_A2.5261.00
45_T57_S2.4511.00
47_T57_S2.2801.00
97_A171_F2.1281.00
133_F150_L2.1241.00
98_A127_M2.1181.00
56_L100_A2.0951.00
75_F159_A2.0641.00
110_L172_L2.0591.00
95_E98_A2.0151.00
70_T87_E1.9921.00
40_D43_T1.9781.00
51_A173_T1.9601.00
86_C137_F1.9501.00
87_E139_D1.9011.00
96_L133_F1.8591.00
121_L154_T1.8501.00
109_V171_F1.8181.00
72_R87_E1.8091.00
68_T89_T1.7981.00
134_T153_V1.7781.00
94_P98_A1.7581.00
51_A103_T1.7371.00
114_L167_D1.6461.00
69_V92_P1.6321.00
54_T101_G1.6011.00
112_H170_E1.5831.00
110_L170_E1.5501.00
91_V96_L1.5321.00
133_F166_V1.5301.00
105_D173_T1.5181.00
111_F166_V1.5181.00
64_R135_W1.5041.00
47_T168_G1.4921.00
28_F86_C1.4591.00
106_A171_F1.4541.00
52_V55_E1.4491.00
74_D85_D1.4421.00
93_F126_C1.4411.00
60_Y64_R1.4321.00
56_L99_A1.3891.00
42_D61_D1.3691.00
68_T136_A1.3591.00
65_A99_A1.3431.00
58_L99_A1.3331.00
111_F152_V1.3311.00
131_V154_T1.3121.00
136_A141_P1.2771.00
62_E65_A1.2671.00
109_V126_C1.2521.00
75_F162_G1.2421.00
51_A105_D1.2011.00
22_Q137_F1.1771.00
177_R182_K1.1521.00
178_G181_E1.1321.00
22_Q72_R1.1161.00
44_W60_Y1.1091.00
66_L91_V1.1041.00
93_F169_V1.0931.00
89_T135_W1.0631.00
63_F150_L1.0581.00
67_D95_E1.0571.00
177_R181_E1.0461.00
113_A163_A1.0130.99
123_L171_F1.0120.99
71_Q132_L1.0100.99
154_T162_G1.0040.99
33_K36_T1.0030.99
48_V52_V1.0020.99
125_D157_K0.9970.99
41_R60_Y0.9810.99
33_K37_P0.9810.99
28_F137_F0.9700.99
128_R131_V0.9700.99
107_V173_T0.9690.99
51_A106_A0.9690.99
119_T160_Y0.9640.99
34_G37_P0.9590.99
87_E138_D0.9580.99
32_S36_T0.9520.99
61_D64_R0.9480.99
119_T163_A0.9470.99
25_T143_P0.9320.99
52_V171_F0.9290.99
64_R136_A0.9280.99
38_N144_P0.9250.99
50_G55_E0.9230.99
75_F86_C0.9190.99
125_D156_H0.9090.99
102_V171_F0.9060.99
97_A102_V0.9050.99
46_F150_L0.9010.99
44_W150_L0.8990.99
67_D92_P0.8900.99
69_V95_E0.8790.98
119_T161_K0.8660.98
91_V135_W0.8650.98
125_D188_T0.8570.98
122_P125_D0.8540.98
28_F84_L0.8500.98
86_C138_D0.8500.98
137_F146_H0.8440.98
152_V163_A0.8390.98
93_F152_V0.8220.98
58_L100_A0.8170.98
170_E176_Q0.8160.98
66_L95_E0.8120.97
48_V56_L0.8000.97
137_F143_P0.7990.97
109_V169_V0.7940.97
18_I22_Q0.7860.97
42_D60_Y0.7810.97
78_V160_Y0.7790.97
52_V100_A0.7730.97
18_I84_L0.7720.97
69_V132_L0.7690.97
110_L181_E0.7670.96
25_T86_C0.7660.96
76_H83_K0.7660.96
153_V162_G0.7650.96
135_W141_P0.7630.96
102_V123_L0.7610.96
125_D129_E0.7550.96
49_T55_E0.7550.96
61_D65_A0.7510.96
39_W114_L0.7510.96
143_P146_H0.7460.96
135_W150_L0.7400.96
91_V133_F0.7290.95
133_F152_V0.7260.95
180_W189_A0.7260.95
95_E99_A0.7240.95
179_Y183_R0.7240.95
91_V95_E0.7210.95
24_E27_K0.7190.95
68_T91_V0.7180.95
52_V106_A0.7150.95
32_S165_W0.7130.95
36_T145_E0.7050.94
58_L62_E0.7030.94
47_T55_E0.6970.94
92_P132_L0.6950.94
119_T181_E0.6950.94
19_P22_Q0.6850.93
126_C131_V0.6850.93
152_V166_V0.6760.93
94_P129_E0.6720.93
41_R148_G0.6670.93
39_W46_F0.6660.92
110_L176_Q0.6640.92
108_H176_Q0.6640.92
112_H118_T0.6610.92
134_T152_V0.6610.92
117_Y160_Y0.6600.92
25_T140_D0.6580.92
28_F165_W0.6560.92
129_E132_L0.6530.92
63_F91_V0.6490.92
76_H119_T0.6430.91
75_F153_V0.6420.91
79_T82_S0.6370.91
56_L62_E0.6350.91
132_L153_V0.6340.91
80_G192_W0.6320.90
134_T150_L0.6280.90
160_Y181_E0.6270.90
36_T144_P0.6260.90
97_A127_M0.6240.90
78_V158_Y0.6240.90
50_G106_A0.6230.90
31_L81_W0.6190.90
108_H120_N0.6190.90
86_C153_V0.6180.89
94_P128_R0.6180.89
30_V145_E0.6150.89
83_K86_C0.6110.89
118_T182_K0.6110.89
79_T160_Y0.6100.89
89_T92_P0.6090.89
48_V58_L0.6090.89
93_F97_A0.6050.88
52_V56_L0.6050.88
111_F117_Y0.6030.88
49_T112_H0.6020.88
110_L118_T0.6000.88
110_L177_R0.5980.88
63_F135_W0.5950.88
64_R141_P0.5930.87
125_D131_V0.5890.87
25_T137_F0.5880.87
172_L176_Q0.5850.87
152_V169_V0.5850.87
53_D105_D0.5840.87
97_A100_A0.5820.86
45_T59_S0.5740.86
91_V150_L0.5740.86
46_F58_L0.5730.86
21_G72_R0.5700.85
107_V123_L0.5700.85
99_A102_V0.5700.85
31_L79_T0.5670.85
55_E58_L0.5650.85
37_P115_D0.5650.85
56_L101_G0.5640.85
19_P140_D0.5610.84
108_H175_P0.5600.84
38_N41_R0.5590.84
183_R186_S0.5540.84
76_H79_T0.5530.84
130_E156_H0.5530.84
93_F131_V0.5510.83
93_F171_F0.5440.83
158_Y161_K0.5420.82
117_Y161_K0.5410.82
93_F154_T0.5390.82
178_G182_K0.5380.82
175_P181_E0.5370.82
53_D56_L0.5360.82
179_Y182_K0.5360.82
157_K161_K0.5360.82
51_A172_L0.5350.82
29_P75_F0.5350.82
46_F168_G0.5330.81
67_D91_V0.5330.81
17_R85_D0.5320.81
49_T52_V0.5310.81
54_T174_E0.5310.81
17_R20_P0.5300.81
29_P83_K0.5290.81
78_V81_W0.5290.81
179_Y184_G0.5280.81
96_L150_L0.5240.80
79_T157_K0.5240.80
78_V161_K0.5220.80
88_F154_T0.5210.80
180_W184_G0.5210.80
28_F180_W0.5190.80
51_A55_E0.5180.79
28_F88_F0.5170.79
74_D79_T0.5150.79
110_L120_N0.5150.79
128_R156_H0.5150.79
32_S113_A0.5140.79
72_R84_L0.5110.79
39_W44_W0.5100.78
93_F96_L0.5100.78
50_G53_D0.5070.78
121_L161_K0.5060.78
75_F78_V0.5050.78
120_N181_E0.5040.78
161_K180_W0.5040.78
181_E184_G0.5000.77
105_D174_E0.5000.77
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
2a9dA 2 1 100 0.152 Contact Map
1ogpA 4 1 100 0.155 Contact Map
1soxA 2 1 100 0.156 Contact Map
2blfA 1 1 100 0.173 Contact Map
2bihA 2 1 100 0.173 Contact Map
2biiA 2 0.9646 100 0.184 Contact Map
4pw3A 2 0.9798 100 0.199 Contact Map
2xtsA 2 0.9899 100 0.202 Contact Map
1xdyA 3 0.9899 100 0.205 Contact Map
2nptA 1 0.4646 30.7 0.95 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.0073 seconds.