GREMLIN Database
Q9HQL7 - Uncharacterized protein
UniProt: Q9HQL7 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 183 (159)
Sequences: 10127 (7129)
Seq/√Len: 565.3

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
98_E102_R3.4411.00
52_R85_V2.9291.00
108_S133_D2.7351.00
98_E132_F2.7141.00
41_W46_A2.6831.00
90_G126_M2.6621.00
34_A112_C2.5121.00
6_A108_S2.4791.00
98_E130_R2.3451.00
108_S135_T2.3191.00
16_G68_G2.3041.00
37_L137_V2.2581.00
13_F34_A2.2571.00
111_V124_V2.2381.00
121_S125_R2.0521.00
5_R107_G2.0231.00
96_A100_W1.9801.00
84_F100_W1.9201.00
127_A134_V1.9051.00
7_A106_T1.8751.00
91_A123_T1.8551.00
33_H140_A1.8381.00
15_Q67_P1.8181.00
40_A44_A1.8161.00
33_H36_E1.7761.00
49_A100_W1.7631.00
146_R150_G1.7431.00
42_R81_E1.6691.00
6_A110_V1.6151.00
15_Q73_D1.5421.00
10_L38_L1.5311.00
26_N29_D1.5211.00
67_P70_A1.5181.00
110_V137_V1.5141.00
154_P157_V1.5021.00
41_W110_V1.5011.00
18_A72_T1.4991.00
156_S161_T1.4941.00
51_V91_A1.4821.00
82_P100_W1.4591.00
109_L127_A1.4341.00
47_P104_R1.4331.00
120_V136_L1.4201.00
117_D143_T1.4051.00
10_L112_C1.4031.00
64_Q85_V1.3791.00
35_E39_A1.3611.00
111_V123_T1.3561.00
116_T141_T1.3441.00
136_L141_T1.3401.00
9_V111_V1.3291.00
100_W104_R1.2971.00
54_N69_F1.2871.00
143_T149_D1.2791.00
126_M130_R1.2511.00
39_A43_D1.2511.00
35_E74_G1.2371.00
10_L13_F1.2181.00
54_N85_V1.2171.00
116_T149_D1.1971.00
11_V119_C1.1881.00
99_G103_D1.1821.00
8_L41_W1.1791.00
32_A74_G1.1731.00
102_R132_F1.1621.00
30_A34_A1.1611.00
52_R71_Y1.1571.00
121_S155_P1.1261.00
33_H139_D1.1061.00
15_Q70_A1.0961.00
37_L140_A1.0941.00
38_L42_R1.0851.00
122_T125_R1.0761.00
10_L34_A1.0691.00
96_A99_G1.0341.00
110_V135_T1.0231.00
12_D86_K1.0161.00
54_N64_Q1.0161.00
52_R83_E1.0031.00
156_S160_R0.9901.00
109_L134_V0.9841.00
71_Y83_E0.9771.00
150_G154_P0.9771.00
38_L50_H0.9711.00
138_R163_L0.9561.00
100_W103_D0.9541.00
6_A46_A0.9491.00
124_V136_L0.9481.00
50_H77_P0.9451.00
147_T150_G0.9401.00
36_E40_A0.9251.00
101_L132_F0.9231.00
78_A81_E0.9161.00
70_A76_A0.8971.00
116_T143_T0.8951.00
56_T64_Q0.8941.00
116_T153_L0.8941.00
7_A49_A0.8891.00
30_A142_A0.8861.00
40_A43_D0.8801.00
112_C140_A0.8701.00
35_E77_P0.8671.00
92_F127_A0.8631.00
13_F114_L0.8601.00
50_H71_Y0.8581.00
91_A97_L0.8551.00
37_L112_C0.8471.00
58_A61_P0.8431.00
137_V140_A0.8411.00
15_Q19_D0.8411.00
59_T63_R0.8341.00
31_E35_E0.8261.00
88_V131_G0.8231.00
107_G133_D0.8211.00
77_P81_E0.8181.00
36_E39_A0.8171.00
93_V130_R0.8161.00
154_P158_V0.8111.00
7_A101_L0.8041.00
9_V97_L0.7991.00
17_F119_C0.7981.00
47_P106_T0.7931.00
124_V156_S0.7861.00
49_A104_R0.7801.00
32_A36_E0.7751.00
138_R153_L0.7701.00
47_P100_W0.7631.00
38_L48_I0.7471.00
11_V111_V0.7461.00
111_V134_V0.7441.00
30_A114_L0.7391.00
88_V94_D0.7311.00
15_Q72_T0.7281.00
147_T154_P0.7281.00
31_E72_T0.7271.00
152_R156_S0.7261.00
159_H163_L0.7261.00
34_A140_A0.7241.00
65_G68_G0.7221.00
82_P104_R0.7211.00
50_H80_D0.7211.00
66_E69_F0.7201.00
29_D32_A0.7181.00
128_D161_T0.7141.00
110_V139_D0.7051.00
124_V134_V0.7031.00
35_E76_A0.6991.00
111_V120_V0.6941.00
73_D76_A0.6941.00
114_L142_A0.6911.00
5_R108_S0.6911.00
77_P83_E0.6901.00
67_P73_D0.6901.00
126_M129_N0.6831.00
151_E154_P0.6791.00
117_D144_H0.6781.00
50_H81_E0.6771.00
115_T143_T0.6731.00
52_R69_F0.6711.00
49_A82_P0.6671.00
157_V160_R0.6661.00
151_E155_P0.6631.00
20_P23_G0.6591.00
121_S152_R0.6551.00
19_D28_P0.6541.00
42_R78_A0.6501.00
13_F72_T0.6481.00
39_A78_A0.6421.00
32_A35_E0.6381.00
60_S63_R0.6361.00
72_T75_L0.6321.00
8_L37_L0.6301.00
39_A76_A0.6261.00
42_R80_D0.6221.00
115_T118_H0.6211.00
37_L110_V0.6211.00
65_G70_A0.6191.00
158_V162_A0.6171.00
25_R142_A0.6171.00
90_G129_N0.6161.00
50_H75_L0.6151.00
27_N114_L0.6151.00
99_G102_R0.6121.00
10_L50_H0.6111.00
160_R163_L0.6101.00
41_W47_P0.6101.00
94_D99_G0.6051.00
145_D148_L0.6041.00
93_V129_N0.6001.00
134_V137_V0.5991.00
153_L157_V0.5981.00
18_A31_E0.5981.00
155_P158_V0.5961.00
25_R29_D0.5941.00
14_Q52_R0.5931.00
38_L41_W0.5871.00
89_N123_T0.5861.00
38_L81_E0.5851.00
89_N118_H0.5851.00
101_L106_T0.5801.00
42_R50_H0.5791.00
31_E74_G0.5771.00
17_F115_T0.5741.00
148_L151_E0.5710.99
93_V126_M0.5710.99
115_T144_H0.5680.99
5_R105_D0.5660.99
112_C137_V0.5640.99
71_Y77_P0.5630.99
120_V141_T0.5630.99
89_N128_D0.5630.99
153_L163_L0.5620.99
52_R70_A0.5610.99
118_H144_H0.5610.99
42_R48_I0.5570.99
49_A84_F0.5570.99
116_T163_L0.5550.99
50_H83_E0.5540.99
56_T59_T0.5530.99
18_A27_N0.5510.99
89_N129_N0.5450.99
8_L112_C0.5440.99
13_F30_A0.5440.99
77_P80_D0.5420.99
84_F96_A0.5360.99
53_H62_L0.5270.99
17_F89_N0.5260.99
8_L38_L0.5260.99
14_Q51_V0.5240.99
56_T87_S0.5220.99
29_D33_H0.5180.99
13_F75_L0.5170.99
47_P82_P0.5130.99
19_D67_P0.5090.99
159_H162_A0.5080.99
28_P74_G0.5070.99
135_T162_A0.5010.99
128_D134_V0.5000.99
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
3oqpA 2 0.9945 100 0.17 Contact Map
3mcwA 2 0.9454 100 0.183 Contact Map
3lqyA 2 0.9781 100 0.188 Contact Map
3hb7A 3 0.9508 100 0.191 Contact Map
3irvA 2 0.9672 100 0.194 Contact Map
2fq1A 2 1 100 0.199 Contact Map
3hu5A 3 0.9454 100 0.202 Contact Map
1nbaA 4 0.9945 100 0.206 Contact Map
1nf9A 2 0.929 100 0.206 Contact Map
4l07A 4 0.9727 100 0.207 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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