SYE - HALSA - GREMLIN Contacts

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SYE - Glutamate--tRNA ligase

UniProt:	Q9HQI1	Sequences: MDDELRERVRRAAERAALFNALKHGSDAQVGAIMGPMMGEHPDFRAHGDEIPGVIAPVIEDVNGMSDDEQRARLAELAPEDVEELDSEDEGDDHALPALPNAEAYDEVRMRCAPNPNGPWHVGHARMPSVIGTYKQRYDGSFVVRFDDTDPETKRPDLDAYDQILEDLSYLGFEADEVLTASDRVETYYEHARRLIGMGGAYTCSCPGAEFSDLKNSGEACPHRDKDPETVADEFEAMVDGEYNSGEMVLRVKTDITHKNPALRDWVAFRMVDTPHPRDAASGYRCWPMLDFQSGVDDHRTGVTHIIRGIDLQDSAKRQRFLYEYFGWEYPEVVHWGHVQLDAYDVAMSTSTIKERIAAGELEGWDDPRAPTMQSIRRRGIRGAAVVDAMVELGTSSSDVELAMSAVYANNRDLVDDTAPRQFLVRDGFEARGEGPEESHEAVEVPVDDGPDEATPQVHPEHPDRGDREIPVGERVLVEATDLPAAGDRVWLKGYGPVRYDGERFAFLDADIDIVREEGVDVVQWVPAEHNVDVRLRTMDGDVTGYAEPGFADRDADEIVQFVRVGFARVDAHRDGGASVAYFTHP	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	586 (486)
Sequences:	2497 (1245)
Seq/√Len:	56.5

ECOLI - SYQ
HALSA - SYE
SULSO - SYE

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
220_A	225_D	5.361	1.00
193_R	236_E	4.467	1.00
244_N	247_E	4.209	1.00
227_D	231_V	4.104	1.00
233_D	237_A	4.013	1.00
205_S	248_M	3.886	1.00
237_A	242_E	3.883	1.00
156_P	162_D	3.713	1.00
533_D	546_Y	3.667	1.00
434_E	509_D	3.389	1.00
455_T	469_E	3.323	1.00
186_E	283_G	3.302	1.00
206_C	214_L	3.186	1.00
200_G	325_Y	3.081	1.00
534_V	547_A	3.067	1.00
432_R	509_D	3.058	1.00
427_D	480_A	2.989	1.00
456_P	494_G	2.909	1.00
354_K	358_A	2.842	1.00
186_E	190_E	2.825	1.00
275_P	282_S	2.818	1.00
431_A	498_V	2.733	1.00
245_S	273_D	2.700	1.00
453_E	469_E	2.672	1.00
194_R	198_M	2.584	1.00
555_D	558_E	2.559	1.00
119_P	159_D	2.556	1.00
169_S	174_E	2.541	1.00
207_P	210_E	2.529	1.00
237_A	243_Y	2.462	1.00
188_Y	297_D	2.424	1.00
382_R	414_L	2.404	1.00
355_E	359_A	2.390	1.00
96_L	138_Y	2.381	1.00
196_I	235_F	2.371	1.00
438_E	474_E	2.315	1.00
236_E	240_D	2.212	1.00
429_F	508_L	2.184	1.00
244_N	273_D	2.180	1.00
193_R	197_G	2.158	1.00
527_P	530_H	2.157	1.00
473_G	527_P	2.151	1.00
424_L	547_A	2.148	1.00
234_E	243_Y	2.136	1.00
268_A	322_L	2.111	1.00
455_T	467_D	2.106	1.00
233_D	242_E	2.082	1.00
489_R	517_E	2.073	1.00
186_E	239_V	2.073	1.00
324_E	330_Y	2.072	1.00
220_A	256_I	2.046	1.00
384_A	418_T	2.046	1.00
127_M	309_G	2.046	1.00
210_E	213_D	2.026	1.00
194_R	327_G	2.003	1.00
388_D	392_E	2.002	1.00
436_P	450_G	1.994	1.00
192_A	250_L	1.979	1.00
430_E	475_R	1.979	1.00
462_H	465_R	1.965	1.00
531_N	546_Y	1.962	1.00
536_L	545_G	1.960	1.00
129_S	173_F	1.952	1.00
239_V	286_C	1.950	1.00
183_D	278_R	1.947	1.00
414_L	418_T	1.934	1.00
416_D	461_E	1.897	1.00
214_L	219_E	1.886	1.00
165_L	178_V	1.873	1.00
181_A	293_Q	1.859	1.00
479_E	565_V	1.852	0.99
471_P	549_P	1.849	0.99
533_D	544_T	1.849	0.99
187_T	191_H	1.829	0.99
493_K	563_V	1.821	0.99
434_E	507_F	1.815	0.99
299_H	329_E	1.781	0.99
109_R	141_S	1.753	0.99
432_R	507_F	1.745	0.99
513_D	517_E	1.739	0.99
109_R	143_V	1.721	0.99
384_A	414_L	1.689	0.99
189_Y	236_E	1.677	0.99
144_V	165_L	1.657	0.99
197_G	232_A	1.654	0.99
233_D	243_Y	1.651	0.99
161_Y	277_P	1.642	0.99
205_S	226_K	1.638	0.99
132_G	142_F	1.638	0.99
424_L	534_V	1.637	0.99
97_P	100_P	1.620	0.99
262_A	315_S	1.616	0.99
162_D	165_L	1.605	0.99
107_E	141_S	1.594	0.98
127_M	131_I	1.590	0.98
109_R	303_V	1.588	0.98
432_R	475_R	1.574	0.98
291_D	315_S	1.573	0.98
439_S	529_E	1.566	0.98
198_M	325_Y	1.558	0.98
187_T	190_E	1.557	0.98
427_D	481_T	1.529	0.98
431_A	508_L	1.511	0.98
127_M	307_I	1.510	0.98
187_T	300_R	1.498	0.98
422_Q	458_V	1.496	0.98
554_R	560_V	1.486	0.98
459_H	465_R	1.482	0.97
92_D	137_R	1.480	0.97
457_Q	493_K	1.470	0.97
97_P	101_N	1.470	0.97
203_T	250_L	1.468	0.97
489_R	513_D	1.465	0.97
494_G	563_V	1.463	0.97
105_Y	108_V	1.461	0.97
165_L	169_S	1.460	0.97
206_C	221_C	1.460	0.97
228_P	231_V	1.459	0.97
348_M	354_K	1.458	0.97
431_A	476_V	1.441	0.97
262_A	314_D	1.421	0.97
191_H	300_R	1.419	0.97
273_D	285_R	1.417	0.97
188_Y	293_Q	1.415	0.97
198_M	327_G	1.399	0.96
191_H	296_V	1.397	0.96
489_R	499_R	1.396	0.96
337_G	396_S	1.390	0.96
381_I	407_V	1.390	0.96
353_I	371_P	1.389	0.96
206_C	219_E	1.386	0.96
322_L	326_F	1.368	0.96
433_G	512_I	1.368	0.96
575_D	578_A	1.365	0.96
197_G	229_E	1.363	0.96
411_N	584_T	1.362	0.96
162_D	166_E	1.358	0.96
204_C	211_F	1.355	0.96
190_E	197_G	1.350	0.96
439_S	450_G	1.348	0.96
471_P	530_H	1.344	0.95
337_G	400_V	1.336	0.95
160_A	354_K	1.334	0.95
535_R	578_A	1.332	0.95
141_S	176_D	1.326	0.95
453_E	471_P	1.321	0.95
175_A	178_V	1.319	0.95
126_R	339_V	1.318	0.95
562_F	581_A	1.313	0.95
378_R	571_D	1.310	0.95
429_F	480_A	1.297	0.95
103_E	107_E	1.291	0.94
127_M	130_V	1.288	0.94
382_R	385_A	1.274	0.94
226_K	230_T	1.272	0.94
429_F	435_G	1.268	0.94
211_F	249_V	1.267	0.94
538_T	583_F	1.259	0.94
392_E	410_N	1.249	0.93
436_P	473_G	1.241	0.93
143_V	176_D	1.240	0.93
531_N	549_P	1.227	0.93
500_Y	508_L	1.224	0.93
532_V	547_A	1.222	0.93
181_A	297_D	1.217	0.92
189_Y	286_C	1.216	0.92
363_E	573_H	1.215	0.92
190_E	193_R	1.210	0.92
296_V	300_R	1.208	0.92
538_T	568_A	1.208	0.92
99_L	105_Y	1.204	0.92
197_G	236_E	1.204	0.92
480_A	504_R	1.197	0.92
205_S	227_D	1.196	0.92
382_R	411_N	1.194	0.92
499_R	511_D	1.192	0.92
296_V	326_F	1.190	0.92
102_A	106_D	1.184	0.91
194_R	197_G	1.184	0.91
422_Q	550_G	1.164	0.91
262_A	317_K	1.155	0.90
344_Y	403_A	1.154	0.90
218_G	261_P	1.149	0.90
557_D	572_A	1.142	0.90
498_V	510_A	1.141	0.90
338_H	349_S	1.140	0.90
426_R	536_L	1.133	0.89
559_I	584_T	1.125	0.89
295_G	322_L	1.123	0.89
166_E	169_S	1.122	0.89
132_G	173_F	1.112	0.88
457_Q	563_V	1.110	0.88
299_H	328_W	1.103	0.88
174_E	179_L	1.098	0.88
213_D	217_S	1.096	0.88
96_L	137_R	1.085	0.87
451_P	529_E	1.082	0.87
425_V	526_V	1.081	0.87
143_V	179_L	1.079	0.87
249_V	267_V	1.078	0.87
417_D	461_E	1.076	0.87
141_S	177_E	1.073	0.87
451_P	530_H	1.070	0.86
402_L	406_A	1.056	0.86
355_E	361_E	1.055	0.86
388_D	410_N	1.054	0.86
166_E	374_Q	1.048	0.85
226_K	234_E	1.041	0.85
547_A	551_F	1.039	0.85
556_A	570_V	1.037	0.85
191_H	295_G	1.034	0.85
134_Y	307_I	1.031	0.84
307_I	334_V	1.031	0.84
490_V	523_V	1.028	0.84
430_E	507_F	1.025	0.84
459_H	466_G	1.024	0.84
291_D	318_R	1.020	0.84
315_S	318_R	1.018	0.84
243_Y	247_E	1.016	0.84
267_V	289_M	1.014	0.83
152_E	272_V	1.013	0.83
296_V	328_W	1.013	0.83
205_S	247_E	1.009	0.83
237_A	248_M	1.004	0.83
199_G	231_V	1.001	0.83
420_P	558_E	1.000	0.83
381_I	385_A	0.989	0.82
390_M	393_L	0.986	0.82
376_I	385_A	0.984	0.81
381_I	411_N	0.983	0.81
345_D	541_G	0.980	0.81
89_D	134_Y	0.977	0.81
423_F	526_V	0.976	0.81
376_I	411_N	0.974	0.81
323_Y	330_Y	0.973	0.81
227_D	230_T	0.970	0.81
473_G	530_H	0.964	0.80
497_P	522_V	0.963	0.80
554_R	570_V	0.962	0.80
258_H	263_L	0.961	0.80
208_G	212_S	0.960	0.80
437_E	450_G	0.960	0.80
263_L	317_K	0.960	0.80
456_P	470_I	0.959	0.80
406_A	409_A	0.956	0.80
473_G	529_E	0.956	0.80
381_I	408_Y	0.951	0.79
155_R	159_D	0.951	0.79
143_V	177_E	0.950	0.79
337_G	398_S	0.946	0.79
488_D	523_V	0.941	0.79
142_F	173_F	0.941	0.79
470_I	526_V	0.939	0.78
204_C	221_C	0.938	0.78
89_D	137_R	0.938	0.78
475_R	528_A	0.937	0.78
363_E	574_R	0.934	0.78
130_V	309_G	0.932	0.78
420_P	465_R	0.931	0.78
307_I	395_T	0.922	0.77
167_D	374_Q	0.921	0.77
392_E	413_D	0.920	0.77
152_E	155_R	0.916	0.77
478_V	483_L	0.916	0.77
255_D	258_H	0.914	0.76
323_Y	326_F	0.912	0.76
475_R	529_E	0.909	0.76
296_V	322_L	0.908	0.76
101_N	105_Y	0.902	0.75
459_H	462_H	0.902	0.75
99_L	102_A	0.899	0.75
210_E	214_L	0.899	0.75
500_Y	510_A	0.897	0.75
203_T	231_V	0.896	0.75
353_I	370_A	0.892	0.75
188_Y	296_V	0.891	0.75
470_I	494_G	0.889	0.74
205_S	231_V	0.884	0.74
570_V	574_R	0.883	0.74
109_R	302_G	0.882	0.74
392_E	406_A	0.882	0.74
206_C	223_H	0.881	0.74
376_I	386_V	0.876	0.73
127_M	390_M	0.876	0.73
203_T	248_M	0.876	0.73
211_F	267_V	0.876	0.73
99_L	103_E	0.872	0.73
481_T	565_V	0.869	0.73
420_P	458_V	0.863	0.72
200_G	204_C	0.863	0.72
209_A	213_D	0.862	0.72
193_R	240_D	0.857	0.72
451_P	527_P	0.857	0.72
479_E	524_Q	0.856	0.72
193_R	232_A	0.853	0.71
417_D	459_H	0.853	0.71
417_D	462_H	0.849	0.71
501_D	506_A	0.847	0.71
427_D	504_R	0.846	0.71
168_L	173_F	0.841	0.70
197_G	228_P	0.840	0.70
556_A	569_R	0.839	0.70
191_H	194_R	0.837	0.70
382_R	559_I	0.836	0.70
213_D	219_E	0.834	0.70
530_H	549_P	0.833	0.70
295_G	315_S	0.833	0.70
457_Q	494_G	0.832	0.69
196_I	250_L	0.832	0.69
488_D	499_R	0.832	0.69
168_L	309_G	0.831	0.69
551_F	554_R	0.831	0.69
174_E	177_E	0.829	0.69
343_A	393_L	0.829	0.69
410_N	413_D	0.828	0.69
320_R	324_E	0.828	0.69
293_Q	297_D	0.826	0.69
204_C	214_L	0.825	0.69
226_K	231_V	0.822	0.68
261_P	267_V	0.821	0.68
92_D	134_Y	0.820	0.68
184_R	297_D	0.817	0.68
570_V	575_D	0.816	0.68
125_A	386_V	0.815	0.68
236_E	239_V	0.814	0.68
132_G	387_V	0.814	0.68
484_P	500_Y	0.813	0.68
88_E	92_D	0.809	0.67
122_V	376_I	0.806	0.67
218_G	259_K	0.805	0.67
385_A	411_N	0.803	0.67
130_V	393_L	0.802	0.67
338_H	342_D	0.800	0.66
499_R	513_D	0.798	0.66
569_R	572_A	0.798	0.66
357_I	370_A	0.797	0.66
292_F	322_L	0.796	0.66
247_E	273_D	0.792	0.66
129_S	387_V	0.792	0.66
557_D	569_R	0.792	0.66
105_Y	139_D	0.792	0.66
436_P	452_D	0.789	0.65
430_E	528_A	0.787	0.65
129_S	133_T	0.787	0.65
268_A	292_F	0.786	0.65
237_A	240_D	0.781	0.65
127_M	168_L	0.781	0.65
496_G	512_I	0.780	0.64
260_N	317_K	0.780	0.64
434_E	511_D	0.778	0.64
227_D	248_M	0.775	0.64
384_A	388_D	0.775	0.64
473_G	531_N	0.773	0.64
141_S	179_L	0.771	0.64
549_P	552_A	0.771	0.64
556_A	572_A	0.769	0.63
570_V	579_S	0.768	0.63
180_T	277_P	0.767	0.63
409_A	413_D	0.763	0.63
458_V	466_G	0.763	0.63
258_H	317_K	0.762	0.63
174_E	178_V	0.762	0.63
181_A	188_Y	0.762	0.63
205_S	223_H	0.761	0.62
165_L	175_A	0.759	0.62
320_R	332_E	0.758	0.62
176_D	179_L	0.755	0.62
197_G	200_G	0.754	0.62
273_D	282_S	0.753	0.62
543_V	546_Y	0.753	0.62
458_V	470_I	0.752	0.62
383_G	559_I	0.748	0.61
433_G	472_V	0.745	0.61
191_H	326_F	0.745	0.61
131_I	309_G	0.744	0.61
95_A	98_A	0.743	0.61
161_Y	180_T	0.742	0.61
295_G	318_R	0.740	0.60
128_P	173_F	0.739	0.60
498_V	508_L	0.738	0.60
430_E	435_G	0.737	0.60
452_D	512_I	0.735	0.60
130_V	373_M	0.734	0.60
197_G	283_G	0.734	0.60
576_G	579_S	0.734	0.60
146_F	178_V	0.733	0.60
193_R	235_F	0.733	0.60
462_H	466_G	0.730	0.59
431_A	510_A	0.730	0.59
204_C	261_P	0.729	0.59
497_P	515_V	0.728	0.59
195_L	268_A	0.728	0.59
320_R	330_Y	0.727	0.59
99_L	107_E	0.726	0.59
313_Q	334_V	0.726	0.59
489_R	519_G	0.725	0.59
381_I	386_V	0.724	0.59
193_R	228_P	0.723	0.59
497_P	516_R	0.723	0.59
187_T	296_V	0.721	0.58
254_T	266_W	0.721	0.58
152_E	274_T	0.720	0.58
156_P	161_Y	0.717	0.58
326_F	329_E	0.717	0.58
547_A	579_S	0.716	0.58
293_Q	300_R	0.716	0.58
433_G	510_A	0.716	0.58
435_G	512_I	0.715	0.58
299_H	325_Y	0.715	0.58
324_E	327_G	0.714	0.58
436_P	474_E	0.714	0.58
199_G	228_P	0.710	0.57
96_L	99_L	0.710	0.57
346_V	404_M	0.707	0.57
338_H	352_T	0.707	0.57
436_P	451_P	0.705	0.57
110_M	113_A	0.702	0.56
436_P	512_I	0.701	0.56
560_V	570_V	0.699	0.56
187_T	194_R	0.699	0.56
478_V	523_V	0.697	0.56
458_V	467_D	0.697	0.56
140_G	304_T	0.695	0.56
110_M	135_K	0.694	0.55
433_G	476_V	0.694	0.55
194_R	325_Y	0.694	0.55
517_E	522_V	0.694	0.55
505_F	508_L	0.693	0.55
382_R	418_T	0.692	0.55
189_Y	284_Y	0.691	0.55
89_D	92_D	0.691	0.55
323_Y	331_P	0.690	0.55
233_D	236_E	0.688	0.55
316_A	335_H	0.688	0.55
229_E	233_D	0.686	0.55
94_H	103_E	0.686	0.55
226_K	248_M	0.685	0.54
419_A	559_I	0.685	0.54
99_L	106_D	0.684	0.54
96_L	100_P	0.681	0.54
295_G	323_Y	0.679	0.54
105_Y	332_E	0.679	0.54
252_V	322_L	0.679	0.54
437_E	452_D	0.677	0.54
184_R	187_T	0.677	0.54
422_Q	551_F	0.677	0.54
252_V	268_A	0.674	0.53
347_A	399_D	0.674	0.53
296_V	323_Y	0.674	0.53
299_H	331_P	0.673	0.53
212_S	215_K	0.673	0.53
243_Y	248_M	0.672	0.53
268_A	295_G	0.671	0.53
338_H	353_I	0.671	0.53
429_F	437_E	0.671	0.53
416_D	458_V	0.670	0.53
113_A	309_G	0.670	0.53
557_D	570_V	0.670	0.53
131_I	134_Y	0.669	0.53
188_Y	291_D	0.669	0.53
109_R	177_E	0.669	0.53
468_R	550_G	0.669	0.53
189_Y	239_V	0.668	0.53
220_A	257_T	0.667	0.53
493_K	523_V	0.667	0.53
91_G	94_H	0.667	0.53
206_C	211_F	0.666	0.52
435_G	438_E	0.666	0.52
537_R	580_V	0.665	0.52
396_S	406_A	0.664	0.52
199_G	225_D	0.661	0.52
396_S	400_V	0.658	0.52
437_E	474_E	0.658	0.52
559_I	569_R	0.657	0.51
485_A	505_F	0.656	0.51
94_H	334_V	0.656	0.51
299_H	326_F	0.651	0.51
194_R	326_F	0.651	0.51
349_S	352_T	0.650	0.51
89_D	96_L	0.648	0.50
427_D	544_T	0.648	0.50
262_A	313_Q	0.648	0.50
322_L	325_Y	0.647	0.50
191_H	328_W	0.646	0.50
404_M	408_Y	0.645	0.50
343_A	348_M	0.645	0.50
550_G	553_D	0.641	0.50
290_L	311_D	0.638	0.49
126_R	337_G	0.637	0.49
218_G	256_I	0.636	0.49
163_Q	374_Q	0.636	0.49
402_L	405_S	0.636	0.49
543_V	578_A	0.636	0.49
417_D	584_T	0.636	0.49
516_R	519_G	0.636	0.49
435_G	511_D	0.635	0.49
488_D	497_P	0.633	0.49
544_T	578_A	0.632	0.49
152_E	156_P	0.632	0.49
99_L	302_G	0.632	0.49
451_P	471_P	0.632	0.49
556_A	573_H	0.629	0.48
570_V	573_H	0.628	0.48
188_Y	295_G	0.628	0.48
234_E	248_M	0.627	0.48
96_L	134_Y	0.627	0.48
180_T	278_R	0.627	0.48
221_C	256_I	0.626	0.48
313_Q	317_K	0.626	0.48
535_R	580_V	0.625	0.48
539_M	542_D	0.625	0.48
438_E	450_G	0.624	0.48
102_A	105_Y	0.624	0.48
205_S	234_E	0.624	0.48
118_G	365_W	0.624	0.48
471_P	527_P	0.622	0.48
190_E	194_R	0.622	0.48
103_E	302_G	0.621	0.48
161_Y	278_R	0.619	0.47
192_A	269_F	0.619	0.47
268_A	296_V	0.619	0.47
223_H	231_V	0.619	0.47
348_M	376_I	0.618	0.47
131_I	336_W	0.617	0.47
231_V	253_K	0.615	0.47
267_V	272_V	0.614	0.47
203_T	234_E	0.613	0.47
462_H	470_I	0.611	0.46
451_P	455_T	0.611	0.46
233_D	248_M	0.610	0.46
282_S	285_R	0.610	0.46
533_D	547_A	0.610	0.46
103_E	332_E	0.609	0.46
220_A	224_R	0.609	0.46
98_A	102_A	0.609	0.46
423_F	470_I	0.607	0.46
262_A	295_G	0.607	0.46
339_V	348_M	0.607	0.46
147_D	181_A	0.607	0.46
360_G	553_D	0.604	0.46
245_S	285_R	0.604	0.46
109_R	176_D	0.604	0.46
231_V	248_M	0.603	0.46
458_V	465_R	0.602	0.45
535_R	542_D	0.602	0.45
90_E	95_A	0.602	0.45
461_E	523_V	0.600	0.45
98_A	103_E	0.600	0.45
189_Y	193_R	0.600	0.45
91_G	95_A	0.599	0.45
99_L	138_Y	0.599	0.45
191_H	322_L	0.598	0.45
452_D	472_V	0.598	0.45
188_Y	191_H	0.596	0.45
532_V	552_A	0.596	0.45
215_K	262_A	0.596	0.45
557_D	584_T	0.596	0.45
491_W	496_G	0.595	0.45
497_P	517_E	0.595	0.45
405_S	409_A	0.595	0.45
416_D	421_R	0.594	0.45
146_F	309_G	0.594	0.45
418_T	462_H	0.593	0.44
180_T	297_D	0.593	0.44
258_H	261_P	0.591	0.44
290_L	350_T	0.591	0.44
458_V	550_G	0.589	0.44
579_S	583_F	0.587	0.44
493_K	524_Q	0.586	0.44
323_Y	328_W	0.586	0.44
376_I	585_H	0.584	0.44
398_S	406_A	0.584	0.44
399_D	584_T	0.582	0.43
433_G	498_V	0.582	0.43
487_G	499_R	0.581	0.43
388_D	414_L	0.581	0.43
354_K	406_A	0.580	0.43
536_L	568_A	0.579	0.43
156_P	277_P	0.578	0.43
185_V	277_P	0.577	0.43
307_I	390_M	0.577	0.43
237_A	245_S	0.575	0.43
398_S	402_L	0.573	0.42
506_A	509_D	0.573	0.42
106_D	109_R	0.570	0.42
318_R	322_L	0.570	0.42
92_D	563_V	0.570	0.42
135_K	140_G	0.568	0.42
416_D	459_H	0.567	0.42
216_N	256_I	0.567	0.42
88_E	96_L	0.567	0.42
311_D	350_T	0.566	0.42
242_E	247_E	0.565	0.41
210_E	223_H	0.564	0.41
192_A	235_F	0.563	0.41
85_L	88_E	0.562	0.41
385_A	414_L	0.562	0.41
256_I	261_P	0.562	0.41
477_L	526_V	0.561	0.41
382_R	407_V	0.561	0.41
370_A	375_S	0.561	0.41
245_S	272_V	0.560	0.41
261_P	315_S	0.558	0.41
417_D	464_D	0.558	0.41
212_S	314_D	0.557	0.41
191_H	206_C	0.557	0.41
105_Y	334_V	0.557	0.41
349_S	353_I	0.556	0.41
109_R	304_T	0.555	0.40
244_N	248_M	0.555	0.40
475_R	507_F	0.554	0.40
534_V	538_T	0.554	0.40
88_E	93_D	0.554	0.40
480_A	506_A	0.554	0.40
155_R	277_P	0.554	0.40
254_T	336_W	0.553	0.40
569_R	584_T	0.551	0.40
416_D	462_H	0.551	0.40
436_P	496_G	0.551	0.40
133_T	136_Q	0.551	0.40
126_R	348_M	0.550	0.40
292_F	453_E	0.550	0.40
302_G	331_P	0.550	0.40
532_V	579_S	0.549	0.40
353_I	375_S	0.549	0.40
458_V	468_R	0.548	0.40
472_V	495_Y	0.548	0.40
297_D	315_S	0.547	0.40
554_R	558_E	0.547	0.40
194_R	200_G	0.546	0.40
430_E	477_L	0.545	0.39
289_M	295_G	0.545	0.39
484_P	488_D	0.544	0.39
99_L	332_E	0.543	0.39
439_S	474_E	0.543	0.39
191_H	327_G	0.543	0.39
574_R	580_V	0.542	0.39
128_P	168_L	0.542	0.39
102_A	107_E	0.541	0.39
142_F	168_L	0.541	0.39
343_A	346_V	0.540	0.39
262_A	398_S	0.540	0.39
575_D	579_S	0.540	0.39
211_F	214_L	0.539	0.39
245_S	248_M	0.539	0.39
196_I	228_P	0.538	0.39
208_G	267_V	0.538	0.39
120_W	164_I	0.537	0.39
408_Y	541_G	0.537	0.39
152_E	162_D	0.535	0.38
530_H	534_V	0.535	0.38
478_V	505_F	0.535	0.38
534_V	579_S	0.534	0.38
225_D	256_I	0.534	0.38
223_H	226_K	0.534	0.38
491_W	522_V	0.534	0.38
499_R	517_E	0.533	0.38
292_F	302_G	0.533	0.38
436_P	472_V	0.532	0.38
536_L	544_T	0.532	0.38
333_V	478_V	0.528	0.38
191_H	292_F	0.528	0.38
230_T	233_D	0.528	0.38
388_D	409_A	0.527	0.38
119_P	163_Q	0.527	0.38
152_E	273_D	0.527	0.38
175_A	387_V	0.526	0.37
216_N	219_E	0.525	0.37
95_A	134_Y	0.525	0.37
454_A	472_V	0.524	0.37
186_E	240_D	0.524	0.37
268_A	318_R	0.523	0.37
144_V	175_A	0.522	0.37
533_D	545_G	0.522	0.37
475_R	509_D	0.521	0.37
551_F	570_V	0.521	0.37
362_L	370_A	0.520	0.37
277_P	370_A	0.520	0.37
508_L	511_D	0.520	0.37
191_H	323_Y	0.520	0.37
170_Y	377_R	0.519	0.37
357_I	364_G	0.519	0.37
433_G	437_E	0.518	0.37
458_V	462_H	0.518	0.37
420_P	457_Q	0.517	0.37
376_I	424_L	0.517	0.37
214_L	222_P	0.516	0.36
231_V	250_L	0.516	0.36
381_I	585_H	0.516	0.36
416_D	584_T	0.516	0.36
516_R	520_V	0.515	0.36
94_H	332_E	0.515	0.36
535_R	543_V	0.515	0.36
95_A	99_L	0.515	0.36
537_R	574_R	0.515	0.36
406_A	410_N	0.515	0.36
209_A	212_S	0.514	0.36
547_A	562_F	0.513	0.36
135_K	142_F	0.513	0.36
100_P	106_D	0.513	0.36
427_D	565_V	0.513	0.36
139_D	373_M	0.513	0.36
115_N	150_D	0.513	0.36
422_Q	560_V	0.512	0.36
110_M	140_G	0.512	0.36
463_P	466_G	0.512	0.36
404_M	409_A	0.510	0.36
424_L	562_F	0.510	0.36
497_P	512_I	0.510	0.36
180_T	188_Y	0.509	0.36
344_Y	401_E	0.509	0.36
422_Q	554_R	0.508	0.36
390_M	396_S	0.507	0.36
348_M	361_E	0.507	0.36
254_T	264_R	0.507	0.36
432_R	506_A	0.507	0.36
127_M	134_Y	0.506	0.35
258_H	262_A	0.506	0.35
228_P	236_E	0.505	0.35
111_R	114_P	0.505	0.35
565_V	568_A	0.504	0.35
481_T	576_G	0.504	0.35
434_E	463_P	0.504	0.35
136_Q	168_L	0.502	0.35
163_Q	211_F	0.502	0.35
204_C	249_V	0.502	0.35
162_D	277_P	0.502	0.35
511_D	515_V	0.501	0.35
295_G	584_T	0.500	0.35

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
3aiiA	1	0.7662	100	0.305	Contact Map
4r3zC	1	0.8208	100	0.332	Contact Map
2hz7A	1	0.8208	100	0.342	Contact Map
4h3sA	1	0.8532	100	0.351	Contact Map
1qtqA	1	0.8157	100	0.351	Contact Map
5bnzA	1	0.8259	100	0.355	Contact Map
4p2bA	2	0.7833	100	0.365	Contact Map
3al0C	1	0.8038	100	0.709	Contact Map
2cfoA	1	0.7031	100	0.71	Contact Map
4griA	1	0.7116	100	0.712	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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