Q9HQG9 - HALSA - GREMLIN Contacts

Home
GREMLIN
- Submit - Monomer
- Submit - Complex
Contacts
Metagenomics
- Contacts
- Structures
Structures
- List
Old Projects
- Complexes (2014)
- PFAM (2013)

Q9HQG9 - Uncharacterized protein

UniProt:	Q9HQG9	Sequences: MTIFKETVETEPLTVSEAKALLSEVETERALDEDRELRFELSRAIEHANRFALLEPAESREFVDELLALDVLDDEAVAYKIVDLLPRTRTELRSVFANERYAMSGDELDEILDVVAKYV	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	119 (114)
Sequences:	112 (82)
Seq/√Len:	7.6

HALSA - Q9HQG9

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
92_L	108_L	4.345	0.98
65_E	117_K	3.659	0.95
62_F	85_L	3.351	0.92
63_V	82_V	3.089	0.88
81_I	115_V	3.015	0.86
51_F	80_K	2.555	0.75
8_V	87_R	2.216	0.64
18_A	117_K	2.114	0.60
79_Y	83_D	1.995	0.55
16_S	62_F	1.837	0.49
58_E	61_E	1.816	0.48
55_E	59_S	1.808	0.48
37_L	79_Y	1.756	0.46
77_V	82_V	1.698	0.44
58_E	85_L	1.695	0.43
42_S	48_A	1.693	0.43
22_L	26_E	1.679	0.43
73_D	80_K	1.614	0.40
4_F	91_E	1.603	0.40
22_L	48_A	1.593	0.40
3_I	51_F	1.588	0.39
76_A	96_F	1.587	0.39
28_E	107_E	1.508	0.36
54_L	85_L	1.486	0.36
18_A	87_R	1.479	0.35
15_V	53_L	1.405	0.33
43_R	91_E	1.404	0.33
16_S	83_D	1.402	0.32
89_R	109_D	1.398	0.32
96_F	106_D	1.382	0.32
26_E	105_G	1.348	0.31
17_E	60_R	1.342	0.30
46_E	107_E	1.281	0.28
65_E	114_V	1.261	0.28
16_S	87_R	1.257	0.28
82_V	115_V	1.253	0.27
23_S	111_I	1.239	0.27
41_L	45_I	1.211	0.26
61_E	65_E	1.199	0.26
18_A	37_L	1.192	0.26
28_E	56_P	1.174	0.25
94_S	101_Y	1.165	0.25
95_V	102_A	1.160	0.25
110_E	113_D	1.160	0.25
46_E	49_N	1.132	0.24
20_A	23_S	1.114	0.23
75_E	79_Y	1.110	0.23
90_T	102_A	1.106	0.23
37_L	118_Y	1.106	0.23
28_E	50_R	1.101	0.23
11_E	36_E	1.100	0.23
20_A	94_S	1.073	0.22
13_L	104_S	1.064	0.22
16_S	85_L	1.061	0.22
21_L	24_E	1.059	0.22
19_K	47_H	1.059	0.22
42_S	98_N	1.052	0.22
41_L	109_D	1.037	0.21
47_H	107_E	1.033	0.21
36_E	79_Y	1.022	0.21
13_L	51_F	1.022	0.21
2_T	53_L	0.998	0.20
2_T	98_N	0.981	0.20
17_E	29_R	0.973	0.19
41_L	108_L	0.948	0.19
26_E	49_N	0.940	0.19
27_T	102_A	0.940	0.19
91_E	103_M	0.939	0.19
63_V	78_A	0.934	0.19
69_L	84_L	0.930	0.18
7_T	52_A	0.907	0.18
90_T	93_R	0.906	0.18
55_E	58_E	0.900	0.18
17_E	93_R	0.868	0.17
97_A	100_R	0.867	0.17
54_L	62_F	0.866	0.17
70_D	103_M	0.858	0.17
22_L	105_G	0.856	0.17
93_R	99_E	0.847	0.17
85_L	104_S	0.845	0.16
45_I	100_R	0.834	0.16
8_V	52_A	0.829	0.16
56_P	113_D	0.822	0.16
36_E	115_V	0.821	0.16
52_A	64_D	0.821	0.16
95_V	98_N	0.818	0.16
16_S	114_V	0.799	0.15
72_L	96_F	0.795	0.15
24_E	64_D	0.795	0.15
82_V	90_T	0.791	0.15
62_F	82_V	0.788	0.15
20_A	56_P	0.772	0.15
64_D	69_L	0.768	0.15
112_L	117_K	0.765	0.15
19_K	52_A	0.754	0.15
23_S	36_E	0.753	0.15
65_E	68_A	0.753	0.15
29_R	103_M	0.744	0.14
16_S	54_L	0.741	0.14
88_T	111_I	0.737	0.14
63_V	115_V	0.732	0.14
59_S	64_D	0.730	0.14
16_S	19_K	0.711	0.14
34_D	88_T	0.710	0.14
38_R	42_S	0.705	0.14
61_E	64_D	0.699	0.13
6_E	41_L	0.694	0.13
64_D	117_K	0.693	0.13
12_P	52_A	0.688	0.13
61_E	67_L	0.683	0.13
62_F	69_L	0.682	0.13
47_H	97_A	0.677	0.13
4_F	103_M	0.674	0.13
13_L	98_N	0.672	0.13
41_L	89_R	0.665	0.13
53_L	95_V	0.660	0.13
5_K	36_E	0.660	0.13
69_L	113_D	0.659	0.13
44_A	112_L	0.651	0.13
11_E	82_V	0.650	0.13
38_R	46_E	0.650	0.13
7_T	45_I	0.647	0.13
89_R	92_L	0.640	0.12
52_A	111_I	0.635	0.12
8_V	55_E	0.633	0.12
7_T	96_F	0.631	0.12
60_R	83_D	0.625	0.12
54_L	118_Y	0.624	0.12
39_F	82_V	0.615	0.12
22_L	97_A	0.609	0.12
92_L	105_G	0.607	0.12
113_D	117_K	0.605	0.12
88_T	91_E	0.601	0.12
46_E	50_R	0.597	0.12
4_F	43_R	0.595	0.12
42_S	104_S	0.594	0.12
20_A	45_I	0.594	0.12
110_E	115_V	0.592	0.12
22_L	107_E	0.589	0.12
13_L	18_A	0.583	0.11
67_L	77_V	0.581	0.11
39_F	97_A	0.580	0.11
53_L	87_R	0.580	0.11
85_L	117_K	0.580	0.11
80_K	116_A	0.577	0.11
27_T	84_L	0.577	0.11
16_S	37_L	0.574	0.11
66_L	80_K	0.573	0.11
92_L	112_L	0.567	0.11
21_L	28_E	0.564	0.11
16_S	47_H	0.562	0.11
53_L	84_L	0.556	0.11
26_E	107_E	0.554	0.11
8_V	27_T	0.546	0.11
29_R	108_L	0.541	0.11
27_T	59_S	0.536	0.11
25_V	29_R	0.533	0.11
90_T	103_M	0.533	0.11
23_S	37_L	0.529	0.11
52_A	106_D	0.529	0.11
16_S	95_V	0.521	0.10
27_T	37_L	0.521	0.10
19_K	34_D	0.521	0.10
29_R	89_R	0.508	0.10
15_V	55_E	0.507	0.10
61_E	101_Y	0.507	0.10
77_V	96_F	0.505	0.10
14_T	17_E	0.505	0.10
39_F	88_T	0.503	0.10
15_V	57_A	0.503	0.10
71_V	103_M	0.500	0.10

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
4qjfB	1	0.9832	100	0.423	Contact Map
1go3F	1	0.8992	99.9	0.444	Contact Map
2c35A	1	0.9916	99.9	0.545	Contact Map
4aybF	1	0.8739	99.9	0.549	Contact Map
3h0gD	1	0.9832	99.8	0.587	Contact Map
1y14A	1	0.9076	99.8	0.595	Contact Map
3ayhA	1	0.958	99.3	0.708	Contact Map
2ckzA	1	0.9412	98	0.811	Contact Map
2e1fA	2	0.5882	26.2	0.933	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.0055 seconds.