GREMLIN Database
Q9HQF9 - Flagellin A1
UniProt: Q9HQF9 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 207 (187)
Sequences: 306 (248)
Seq/√Len: 18.1

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
49_A52_Q4.5871.00
195_V199_V4.3761.00
65_T80_S4.0841.00
37_M49_A3.4911.00
177_A193_V2.9940.99
41_R54_T2.2560.93
6_R29_S2.2090.93
142_E147_I2.2040.93
139_A144_R2.1660.92
67_T80_S2.1510.92
20_M31_L2.1420.92
20_M90_A2.0670.90
134_S137_V2.0610.90
139_A142_E1.9580.87
134_S150_N1.9370.87
29_S174_G1.8570.84
9_V16_V1.8490.84
56_G89_S1.8460.84
137_V140_D1.8210.83
29_S35_G1.8200.83
7_G16_V1.7960.82
179_L191_Y1.7880.82
35_G85_V1.7570.81
113_L127_T1.7370.80
16_V101_T1.7330.80
31_L35_G1.7310.80
183_T195_V1.7240.79
6_R9_V1.7060.79
174_G184_Q1.6840.78
26_M35_G1.6670.77
14_L25_A1.6640.77
7_G33_D1.6600.77
9_V43_D1.6410.76
104_W171_L1.6370.76
49_A58_S1.6350.76
105_V177_A1.6340.76
88_Q179_L1.6180.75
179_L193_V1.5190.70
52_Q58_S1.5160.70
47_E51_G1.5030.69
186_G196_P1.5000.69
9_V63_F1.4970.69
54_T189_T1.4910.68
185_Y188_S1.4650.67
26_M41_R1.4230.65
37_M52_Q1.3990.63
132_G143_D1.3820.62
50_V54_T1.3780.62
89_S183_T1.3710.62
123_S128_R1.3580.61
11_I17_F1.3370.60
135_A140_D1.3300.59
175_E199_V1.3290.59
21_I36_G1.3210.59
49_A145_I1.3100.58
129_K132_G1.2930.57
4_M44_A1.2640.55
143_D147_I1.2630.55
31_L45_T1.2610.55
9_V178_E1.2550.55
16_V66_I1.2420.54
13_T27_A1.2060.52
102_V146_E1.1970.51
22_L36_G1.1890.51
41_R50_V1.1880.51
33_D37_M1.1690.50
11_I19_A1.1680.49
68_N124_R1.1670.49
102_V127_T1.1370.48
37_M47_E1.1330.47
9_V29_S1.1280.47
7_G37_M1.1260.47
56_G189_T1.1060.46
82_I104_W1.1050.46
183_T199_V1.1020.45
174_G185_Y1.0840.44
121_N170_G1.0820.44
86_V123_S1.0810.44
35_G44_A1.0690.43
57_V95_V1.0620.43
150_N155_E1.0610.43
33_D49_A1.0590.43
10_G14_L1.0580.43
44_A58_S1.0550.43
24_A27_A1.0490.42
52_Q183_T1.0460.42
86_V147_I1.0340.41
7_G23_V1.0330.41
92_S187_A1.0270.41
163_G167_D1.0260.41
68_N102_V1.0090.40
132_G138_L1.0090.40
140_D150_N0.9890.39
41_R59_V0.9810.38
54_T90_A0.9690.37
69_A133_N0.9600.37
57_V99_D0.9600.37
80_S164_T0.9560.37
6_R47_E0.9510.36
35_G199_V0.9510.36
16_V31_L0.9490.36
15_V18_M0.9480.36
13_T25_A0.9450.36
85_V88_Q0.9440.36
98_S125_F0.9420.36
69_A123_S0.9420.36
44_A192_W0.9400.36
118_G121_N0.9390.36
150_N153_A0.9390.36
78_T201_G0.9340.35
50_V56_G0.9330.35
16_V37_M0.9310.35
10_G18_M0.9300.35
12_G20_M0.9260.35
12_G17_F0.9080.34
120_A123_S0.9070.34
15_V19_A0.9040.34
95_V182_T0.8990.34
84_I104_W0.8960.33
39_Q45_T0.8910.33
41_R45_T0.8870.33
10_G17_F0.8850.33
10_G19_A0.8790.32
87_G194_S0.8770.32
117_D123_S0.8710.32
116_T120_A0.8710.32
127_T130_A0.8710.32
181_I191_Y0.8690.32
127_T131_T0.8650.32
50_V183_T0.8630.32
21_I50_V0.8550.31
21_I34_I0.8520.31
13_T36_G0.8520.31
29_S44_A0.8520.31
137_V150_N0.8500.31
29_S113_L0.8460.31
151_A155_E0.8430.31
116_T119_T0.8390.30
24_A34_I0.8350.30
82_I107_P0.8340.30
37_M59_V0.8340.30
140_D144_R0.8300.30
60_T111_T0.8210.29
134_S140_D0.8210.29
116_T128_R0.8180.29
122_S125_F0.8140.29
120_A168_N0.8090.29
59_V138_L0.8080.29
163_G166_N0.8080.29
51_G115_W0.8070.29
118_G124_R0.8060.29
88_Q95_V0.8010.28
143_D164_T0.7990.28
40_S93_G0.7980.28
3_S92_S0.7970.28
69_A78_T0.7950.28
19_A30_T0.7910.28
118_G131_T0.7890.28
13_T24_A0.7860.28
151_A171_L0.7730.27
29_S43_D0.7710.27
163_G168_N0.7670.27
44_A97_V0.7580.26
10_G15_V0.7530.26
135_A155_E0.7530.26
113_L180_V0.7520.26
13_T33_D0.7520.26
35_G40_S0.7470.26
117_D120_A0.7470.26
135_A179_L0.7470.26
50_V184_Q0.7450.26
54_T97_V0.7450.26
120_A170_G0.7440.26
54_T61_G0.7410.25
44_A50_V0.7390.25
4_M47_E0.7390.25
123_S153_A0.7370.25
56_G88_Q0.7290.25
36_G50_V0.7280.25
36_G45_T0.7240.25
37_M62_A0.7220.25
63_F201_G0.7210.25
34_I42_G0.7150.24
178_E182_T0.7120.24
17_F23_V0.7100.24
127_T132_G0.7030.24
40_S55_N0.7020.24
6_R33_D0.6980.23
106_G195_V0.6930.23
80_S200_T0.6930.23
16_V174_G0.6920.23
12_G15_V0.6860.23
191_Y194_S0.6830.23
89_S185_Y0.6820.23
59_V180_V0.6820.23
82_I139_A0.6800.23
19_A28_A0.6790.23
88_Q92_S0.6790.23
7_G48_E0.6700.22
116_T163_G0.6680.22
48_E68_N0.6620.22
78_T167_D0.6600.22
37_M58_S0.6590.22
126_T148_V0.6560.22
40_S190_T0.6500.21
197_E200_T0.6450.21
16_V49_A0.6420.21
13_T21_I0.6390.21
59_V94_N0.6390.21
36_G187_A0.6350.21
16_V90_A0.6310.21
21_I33_D0.6310.21
67_T76_D0.6280.21
18_M30_T0.6270.20
56_G183_T0.6270.20
140_D149_I0.6250.20
130_A143_D0.6240.20
41_R185_Y0.6220.20
9_V61_G0.6190.20
23_V31_L0.6180.20
69_A148_V0.6130.20
14_L18_M0.6110.20
59_V113_L0.6090.20
57_V94_N0.6060.20
94_N189_T0.6040.20
152_T155_E0.6030.20
30_T35_G0.5990.19
37_M56_G0.5980.19
65_T81_D0.5960.19
44_A54_T0.5930.19
31_L39_Q0.5930.19
14_L17_F0.5880.19
51_G100_V0.5880.19
20_M198_S0.5870.19
15_V91_G0.5850.19
26_M199_V0.5770.19
11_I15_V0.5770.19
55_N62_A0.5760.19
119_T168_N0.5750.18
16_V198_S0.5730.18
19_A46_G0.5710.18
122_S128_R0.5700.18
37_M199_V0.5700.18
184_Q191_Y0.5640.18
84_I153_A0.5640.18
3_S44_A0.5560.18
52_Q63_F0.5540.18
23_V48_E0.5540.18
14_L19_A0.5520.18
32_V50_V0.5480.17
176_R180_V0.5480.17
68_N126_T0.5460.17
7_G18_M0.5440.17
80_S117_D0.5410.17
134_S144_R0.5390.17
93_G185_Y0.5380.17
141_A200_T0.5370.17
79_V170_G0.5360.17
60_T63_F0.5360.17
109_Q181_I0.5350.17
135_A139_A0.5350.17
17_F21_I0.5340.17
128_R131_T0.5310.17
107_P175_E0.5300.17
97_V101_T0.5300.17
4_M37_M0.5290.17
69_A129_K0.5280.17
40_S56_G0.5280.17
44_A47_E0.5270.17
123_S126_T0.5230.17
82_I111_T0.5210.17
87_G187_A0.5190.16
41_R89_S0.5140.16
5_R8_Q0.5120.16
37_M41_R0.5090.16
3_S102_V0.5050.16
132_G135_A0.5050.16
89_S179_L0.5030.16
59_V189_T0.5020.16
80_S166_N0.5000.16
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
1gutA 5 0.3237 3.3 0.968 Contact Map
1qleD 1 0.1111 3.2 0.969 Contact Map
1m56D 1 0.1111 2.9 0.969 Contact Map
2bpsA 1 0.1691 2.6 0.97 Contact Map
4kq7A 4 0.3527 2.6 0.97 Contact Map
1fr3A 5 0.3237 2.5 0.971 Contact Map
4iucS 1 0.0242 2.1 0.972 Contact Map
2l8aA 1 0.6232 2.1 0.972 Contact Map
1pp5A 1 0.0918 2 0.972 Contact Map
3mmlB 1 0.2899 1.7 0.973 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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