Q9HQE5 - HALSA - GREMLIN Contacts

Home
GREMLIN
- Submit - Monomer
- Submit - Complex
Contacts
Metagenomics
- Contacts
- Structures
Structures
- List
Old Projects
- Complexes (2014)
- PFAM (2013)

Q9HQE5 - Uncharacterized protein

UniProt:	Q9HQE5	Sequences: MTDVDVAVVGGGPAGSTAAYAAADAGADAVVYEKGVPRSDRDRLGPDSTDAAGFLDYWLDVAGLDVADIPDDVIEHDLADAEFIGPTERVTVDRTGIDNDYDAFGFTFHRARFDDWLRDRAEAAGARYEAGTTVKTVDSHIDGDGHEHTLHLGGGETVTTEYLVLADGPQRQITMRVLDPLLPADTQASTVLSPPDANHIAYQEYRQFPDDVFDDASLKFWWGWMPGETAYPWVFPNQGNVARVGLTMPIGLDIADFDPDDWRLLRADDDKIPSGSEYIHRFLTEVYGDEYDIDTAFPIVDDHGKAGGTETYPISSTQPIESPVEAGIAVTGGAMGATSAFHEGGDHVAHRTGLLAGRLAATGSLEEYNDAWHAAIGDEVKRNVAMANIVGSFGPDDWDDTIRITRSMLDATDTGSVISKSSARSAAGGLKLYGKYRKAKFGLRNGRYVSLHASDYSL	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	458 (345)
Sequences:	13404 (10407)
Seq/√Len:	560.3

ECOLI - UBII UBIH UBIF MHPA FIXC YDIS YGCN CBRA
BACSU - YHJG YETM
HALSA - Q9HQE5 Q9HS24 Q9HS01 Q9HMA0
SULSO - Q97V59 Q97V18 Q97ZK8 Q97W83

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
30_V	129_E	4.218	1.00
34_K	133_T	3.774	1.00
369_N	373_H	3.723	1.00
14_A	349_A	3.642	1.00
7_A	160_T	3.327	1.00
5_D	28_D	3.279	1.00
5_D	161_E	3.041	1.00
32_Y	158_V	2.929	1.00
18_A	164_V	2.880	1.00
72_D	119_D	2.627	1.00
136_T	176_R	2.620	1.00
4_V	30_V	2.502	1.00
7_A	32_Y	2.450	1.00
21_A	357_G	2.437	1.00
165_L	173_I	2.285	1.00
120_R	123_A	2.263	1.00
14_A	331_T	2.236	1.00
17_T	350_H	2.191	1.00
132_T	154_G	2.166	1.00
129_E	132_T	2.107	1.00
115_D	119_D	2.095	1.00
359_L	371_A	2.018	1.00
137_V	163_L	2.003	1.00
20_Y	120_R	1.989	1.00
25_A	361_A	1.987	1.00
120_R	124_A	1.984	1.00
190_T	193_S	1.981	1.00
324_V	366_E	1.975	1.00
5_D	30_V	1.955	1.00
166_A	331_T	1.899	1.00
276_S	280_H	1.889	1.00
191_V	194_P	1.889	1.00
63_G	70_P	1.872	1.00
6_V	27_A	1.868	1.00
19_A	31_V	1.855	1.00
71_D	75_E	1.842	1.00
324_V	329_A	1.816	1.00
190_T	194_P	1.802	1.00
132_T	156_E	1.788	1.00
140_H	159_T	1.781	1.00
140_H	143_G	1.776	1.00
61_V	354_L	1.770	1.00
275_G	278_Y	1.758	1.00
162_Y	365_L	1.745	1.00
353_G	357_G	1.736	1.00
373_H	377_G	1.723	1.00
28_D	127_R	1.679	1.00
283_L	287_Y	1.656	1.00
72_D	75_E	1.634	1.00
283_L	286_V	1.628	1.00
121_A	126_A	1.577	1.00
355_L	359_L	1.564	1.00
18_A	353_G	1.549	1.00
165_L	330_V	1.543	1.00
355_L	371_A	1.543	1.00
148_H	152_L	1.539	1.00
277_E	281_R	1.538	1.00
72_D	123_A	1.533	1.00
23_A	126_A	1.523	1.00
135_K	153_G	1.521	1.00
72_D	120_R	1.519	1.00
278_Y	281_R	1.506	1.00
7_A	158_V	1.504	1.00
219_K	222_W	1.504	1.00
132_T	152_L	1.488	1.00
278_Y	282_F	1.485	1.00
30_V	158_V	1.478	1.00
316_S	384_V	1.478	1.00
177_V	182_L	1.477	1.00
8_V	18_A	1.477	1.00
275_G	279_I	1.467	1.00
281_R	284_T	1.454	1.00
150_L	155_G	1.452	1.00
322_S	325_E	1.448	1.00
160_T	163_L	1.446	1.00
133_T	153_G	1.422	1.00
358_R	371_A	1.411	1.00
164_V	329_A	1.408	1.00
323_P	376_I	1.400	1.00
172_Q	176_R	1.396	1.00
58_W	350_H	1.394	1.00
359_L	367_E	1.389	1.00
189_S	193_S	1.384	1.00
359_L	364_S	1.383	1.00
192_L	195_P	1.367	1.00
149_T	157_T	1.359	1.00
276_S	283_L	1.353	1.00
167_D	171_R	1.348	1.00
90_V	93_D	1.345	1.00
7_A	150_L	1.344	1.00
118_R	130_A	1.341	1.00
58_W	347_H	1.334	1.00
6_V	22_A	1.328	1.00
203_Q	206_R	1.312	1.00
201_A	204_E	1.308	1.00
85_G	89_R	1.304	1.00
71_D	74_I	1.303	1.00
352_T	372_W	1.301	1.00
398_W	401_T	1.299	1.00
275_G	286_V	1.299	1.00
139_S	325_E	1.296	1.00
20_Y	121_A	1.295	1.00
274_S	278_Y	1.294	1.00
143_G	159_T	1.286	1.00
134_V	150_L	1.282	1.00
134_V	137_V	1.281	1.00
322_S	369_N	1.273	1.00
164_V	331_T	1.271	1.00
152_L	158_V	1.267	1.00
136_T	151_H	1.266	1.00
149_T	159_T	1.262	1.00
172_Q	175_M	1.262	1.00
336_G	352_T	1.254	1.00
21_A	65_D	1.253	1.00
150_L	154_G	1.249	1.00
138_D	149_T	1.249	1.00
276_S	279_I	1.248	1.00
276_S	286_V	1.239	1.00
278_Y	283_L	1.237	1.00
13_P	346_D	1.237	1.00
191_V	195_P	1.235	1.00
70_P	74_I	1.228	1.00
151_H	157_T	1.222	1.00
138_D	151_H	1.220	1.00
149_T	152_L	1.215	1.00
275_G	282_F	1.211	1.00
280_H	284_T	1.205	1.00
282_F	285_E	1.205	1.00
202_Y	205_Y	1.201	1.00
9_V	173_I	1.197	1.00
91_T	94_R	1.197	1.00
4_V	7_A	1.196	1.00
64_L	358_R	1.195	1.00
129_E	156_E	1.195	1.00
147_E	152_L	1.191	1.00
85_G	88_E	1.190	1.00
24_D	124_A	1.188	1.00
276_S	285_E	1.187	1.00
147_E	150_L	1.183	1.00
323_P	369_N	1.178	1.00
32_Y	129_E	1.169	1.00
275_G	280_H	1.146	1.00
245_G	248_M	1.144	1.00
118_R	128_Y	1.143	1.00
329_A	368_Y	1.136	1.00
11_G	33_E	1.135	1.00
277_E	280_H	1.130	1.00
18_A	22_A	1.128	1.00
331_T	368_Y	1.126	1.00
23_A	124_A	1.124	1.00
152_L	155_G	1.123	1.00
338_T	348_V	1.122	1.00
7_A	30_V	1.121	1.00
275_G	285_E	1.120	1.00
18_A	331_T	1.118	1.00
279_I	282_F	1.113	1.00
276_S	282_F	1.110	1.00
49_T	52_A	1.109	1.00
273_P	276_S	1.105	1.00
9_V	163_L	1.102	1.00
9_V	134_V	1.094	1.00
324_V	369_N	1.093	1.00
8_V	19_A	1.090	1.00
330_V	334_A	1.088	1.00
138_D	157_T	1.086	1.00
32_Y	152_L	1.082	1.00
134_V	173_I	1.081	1.00
275_G	284_T	1.080	1.00
13_P	350_H	1.070	1.00
279_I	283_L	1.070	1.00
119_D	122_E	1.063	1.00
189_S	192_L	1.062	1.00
182_L	185_D	1.058	1.00
8_V	29_A	1.046	1.00
129_E	158_V	1.045	1.00
274_S	283_L	1.043	1.00
243_R	247_T	1.038	1.00
139_S	327_G	1.038	1.00
274_S	277_E	1.037	1.00
9_V	167_D	1.035	1.00
17_T	21_A	1.023	1.00
351_R	375_A	1.020	1.00
30_V	127_R	1.017	1.00
395_P	399_D	1.015	1.00
118_R	122_E	1.010	1.00
282_F	286_V	1.007	1.00
150_L	153_G	1.007	1.00
32_Y	160_T	1.003	1.00
27_A	361_A	1.000	1.00
20_Y	24_D	1.000	1.00
11_G	16_S	0.987	1.00
275_G	287_Y	0.986	1.00
63_G	74_I	0.985	1.00
17_T	65_D	0.985	1.00
205_Y	208_F	0.982	1.00
245_G	249_P	0.980	1.00
177_V	328_I	0.977	1.00
173_I	328_I	0.973	1.00
137_V	173_I	0.971	1.00
216_A	222_W	0.969	1.00
275_G	283_L	0.964	1.00
137_V	176_R	0.956	1.00
137_V	177_V	0.953	1.00
357_G	361_A	0.950	1.00
139_S	326_A	0.950	1.00
273_P	277_E	0.949	1.00
329_A	356_A	0.945	1.00
342_H	383_N	0.943	1.00
24_D	120_R	0.939	1.00
76_H	79_A	0.939	1.00
397_D	401_T	0.936	1.00
64_L	354_L	0.932	1.00
185_D	321_E	0.930	1.00
181_L	184_A	0.928	1.00
367_E	370_D	0.928	1.00
72_D	116_W	0.928	1.00
20_Y	124_A	0.928	1.00
31_V	128_Y	0.927	1.00
23_A	125_G	0.927	1.00
359_L	362_T	0.926	1.00
362_T	367_E	0.925	1.00
323_P	335_M	0.924	1.00
5_D	27_A	0.917	1.00
202_Y	206_R	0.916	1.00
137_V	328_I	0.914	1.00
152_L	156_E	0.907	1.00
169_P	337_A	0.907	1.00
86_P	89_R	0.905	1.00
60_D	63_G	0.904	1.00
314_I	339_S	0.901	1.00
181_L	185_D	0.899	1.00
112_R	115_D	0.895	1.00
116_W	119_D	0.890	1.00
218_L	222_W	0.890	1.00
220_F	223_G	0.886	1.00
57_Y	351_R	0.885	1.00
330_V	335_M	0.885	1.00
204_E	207_Q	0.882	1.00
134_V	176_R	0.881	1.00
29_A	126_A	0.880	1.00
245_G	250_I	0.880	1.00
281_R	285_E	0.877	1.00
188_A	193_S	0.875	1.00
57_Y	375_A	0.873	1.00
221_W	224_W	0.871	1.00
148_H	151_H	0.870	1.00
148_H	155_G	0.870	1.00
189_S	194_P	0.867	1.00
32_Y	132_T	0.866	1.00
33_E	130_A	0.863	1.00
19_A	29_A	0.862	1.00
52_A	346_D	0.861	1.00
70_P	73_V	0.859	1.00
182_L	320_I	0.853	1.00
59_L	106_F	0.852	1.00
171_R	174_T	0.848	1.00
42_D	45_G	0.845	1.00
384_V	388_N	0.845	1.00
394_G	397_D	0.844	1.00
163_L	328_I	0.841	1.00
207_Q	211_D	0.841	1.00
216_A	219_K	0.837	1.00
278_Y	285_E	0.837	1.00
218_L	223_G	0.836	1.00
84_I	89_R	0.833	1.00
218_L	221_W	0.833	1.00
338_T	380_V	0.830	1.00
147_E	153_G	0.829	1.00
247_T	250_I	0.822	1.00
324_V	365_L	0.818	1.00
81_A	85_G	0.816	1.00
366_E	370_D	0.815	1.00
274_S	280_H	0.815	1.00
69_I	120_R	0.814	1.00
73_V	106_F	0.811	1.00
16_S	121_A	0.810	1.00
279_I	285_E	0.810	1.00
336_G	372_W	0.809	1.00
371_A	374_A	0.790	1.00
346_D	350_H	0.787	1.00
84_I	88_E	0.787	1.00
312_Y	315_S	0.787	1.00
243_R	246_L	0.785	1.00
121_A	125_G	0.784	1.00
138_D	141_I	0.782	1.00
135_K	151_H	0.781	1.00
69_I	116_W	0.780	1.00
377_G	381_K	0.779	1.00
203_Q	207_Q	0.779	1.00
162_Y	329_A	0.779	1.00
367_E	371_A	0.774	1.00
140_H	149_T	0.772	1.00
274_S	286_V	0.771	1.00
246_L	250_I	0.771	1.00
216_A	221_W	0.769	1.00
148_H	153_G	0.769	1.00
280_H	286_V	0.769	1.00
55_L	58_W	0.768	1.00
208_F	212_V	0.766	1.00
277_E	283_L	0.765	1.00
220_F	225_M	0.764	1.00
57_Y	60_D	0.760	1.00
222_W	225_M	0.756	1.00
209_P	212_V	0.755	1.00
338_T	383_N	0.755	1.00
5_D	160_T	0.754	1.00
53_G	107_T	0.752	1.00
183_P	321_E	0.751	1.00
20_Y	65_D	0.751	1.00
23_A	29_A	0.750	1.00
81_A	84_I	0.749	1.00
62_A	69_I	0.745	1.00
4_V	28_D	0.742	1.00
30_V	160_T	0.741	1.00
206_R	209_P	0.741	1.00
363_G	367_E	0.740	1.00
23_A	122_E	0.739	1.00
203_Q	208_F	0.738	1.00
252_L	255_A	0.737	1.00
149_T	155_G	0.736	1.00
374_A	378_D	0.732	1.00
220_F	224_W	0.730	1.00
190_T	195_P	0.730	1.00
59_L	70_P	0.729	1.00
53_G	105_G	0.727	1.00
244_V	248_M	0.724	1.00
112_R	238_Q	0.722	1.00
164_V	360_A	0.722	1.00
165_L	177_V	0.719	1.00
206_R	211_D	0.718	1.00
306_A	309_T	0.715	1.00
218_L	224_W	0.715	1.00
58_W	61_V	0.709	1.00
205_Y	209_P	0.708	1.00
280_H	287_Y	0.707	1.00
73_V	113_F	0.707	1.00
201_A	205_Y	0.706	1.00
150_L	163_L	0.706	1.00
4_V	127_R	0.704	1.00
122_E	127_R	0.703	1.00
394_G	401_T	0.702	1.00
348_V	376_I	0.701	1.00
122_E	125_G	0.699	1.00
253_D	256_D	0.697	1.00
355_L	358_R	0.697	1.00
280_H	285_E	0.696	1.00
341_F	387_A	0.694	1.00
23_A	121_A	0.693	1.00
244_V	247_T	0.693	1.00
396_D	400_D	0.692	1.00
63_G	103_A	0.690	1.00
274_S	282_F	0.688	1.00
223_G	226_P	0.685	1.00
26_G	29_A	0.680	1.00
57_Y	344_G	0.679	1.00
204_E	209_P	0.678	1.00
32_Y	150_L	0.675	1.00
164_V	356_A	0.675	1.00
309_T	312_Y	0.674	1.00
69_I	73_V	0.674	1.00
219_K	223_G	0.674	1.00
188_A	192_L	0.672	1.00
22_A	360_A	0.667	1.00
65_D	69_I	0.665	1.00
246_L	249_P	0.664	1.00
81_A	86_P	0.664	1.00
279_I	287_Y	0.661	1.00
277_E	286_V	0.661	1.00
23_A	127_R	0.658	1.00
233_W	245_G	0.658	1.00
320_I	323_P	0.657	1.00
279_I	286_V	0.656	1.00
274_S	284_T	0.656	1.00
273_P	283_L	0.654	1.00
188_A	191_V	0.654	1.00
208_F	211_D	0.653	1.00
69_I	72_D	0.651	1.00
148_H	154_G	0.650	1.00
18_A	360_A	0.649	1.00
109_H	112_R	0.647	1.00
134_V	172_Q	0.645	1.00
274_S	285_E	0.645	1.00
207_Q	210_D	0.645	1.00
16_S	118_R	0.642	1.00
173_I	176_R	0.642	1.00
134_V	152_L	0.641	1.00
320_I	330_V	0.641	1.00
217_S	220_F	0.639	1.00
394_G	400_D	0.639	1.00
232_P	236_P	0.639	1.00
50_D	110_R	0.637	1.00
82_E	91_T	0.636	1.00
310_E	315_S	0.636	1.00
55_L	347_H	0.636	1.00
396_D	399_D	0.634	1.00
285_E	288_G	0.634	1.00
147_E	151_H	0.631	1.00
207_Q	241_V	0.630	1.00
45_G	130_A	0.630	1.00
275_G	288_G	0.628	1.00
344_G	347_H	0.626	1.00
121_A	128_Y	0.624	1.00
114_D	130_A	0.624	1.00
114_D	118_R	0.623	1.00
148_H	327_G	0.623	1.00
6_V	18_A	0.623	1.00
230_A	237_N	0.622	1.00
276_S	287_Y	0.621	1.00
338_T	342_H	0.621	1.00
116_W	120_R	0.620	1.00
284_T	287_Y	0.620	1.00
280_H	283_L	0.619	1.00
202_Y	207_Q	0.619	1.00
29_A	121_A	0.617	1.00
219_K	224_W	0.614	1.00
9_V	137_V	0.614	1.00
135_K	155_G	0.613	1.00
6_V	162_Y	0.613	1.00
165_L	328_I	0.613	1.00
376_I	380_V	0.612	1.00
147_E	155_G	0.611	1.00
310_E	313_P	0.609	1.00
82_E	85_G	0.608	1.00
21_A	61_V	0.608	1.00
21_A	354_L	0.607	1.00
139_S	328_I	0.607	1.00
119_D	123_A	0.606	1.00
29_A	127_R	0.606	1.00
397_D	400_D	0.604	1.00
235_F	245_G	0.600	1.00
211_D	214_D	0.600	1.00
21_A	24_D	0.597	1.00
189_S	195_P	0.596	1.00
5_D	158_V	0.591	1.00
151_H	154_G	0.590	1.00
319_P	377_G	0.590	1.00
68_D	71_D	0.590	1.00
363_G	366_E	0.588	1.00
217_S	222_W	0.587	1.00
330_V	368_Y	0.586	1.00
17_T	62_A	0.584	1.00
84_I	87_T	0.581	1.00
73_V	116_W	0.579	1.00
209_P	213_F	0.577	1.00
354_L	358_R	0.576	0.99
17_T	117_L	0.576	0.99
325_E	328_I	0.575	0.99
274_S	287_Y	0.575	0.99
312_Y	316_S	0.575	0.99
16_S	128_Y	0.574	0.99
249_P	252_L	0.571	0.99
188_A	194_P	0.569	0.99
378_D	381_K	0.568	0.99
370_D	374_A	0.568	0.99
392_S	395_P	0.568	0.99
28_D	161_E	0.567	0.99
134_V	163_L	0.566	0.99
45_G	118_R	0.565	0.99
52_A	110_R	0.565	0.99
216_A	220_F	0.562	0.99
243_R	250_I	0.561	0.99
177_V	325_E	0.560	0.99
342_H	386_M	0.559	0.99
110_R	114_D	0.559	0.99
19_A	126_A	0.558	0.99
210_D	213_F	0.557	0.99
339_S	342_H	0.557	0.99
394_G	399_D	0.555	0.99
61_V	65_D	0.555	0.99
19_A	121_A	0.554	0.99
81_A	88_E	0.553	0.99
63_G	71_D	0.553	0.99
351_R	372_W	0.552	0.99
273_P	286_V	0.551	0.99
356_A	360_A	0.551	0.99
310_E	314_I	0.547	0.99
278_Y	287_Y	0.546	0.99
139_S	143_G	0.546	0.99
278_Y	286_V	0.543	0.99
25_A	357_G	0.543	0.99
133_T	172_Q	0.540	0.99
151_H	155_G	0.533	0.99
274_S	279_I	0.533	0.99
16_S	114_D	0.532	0.99
319_P	323_P	0.532	0.99
81_A	89_R	0.531	0.99
386_M	389_I	0.531	0.99
22_A	357_G	0.530	0.99
344_G	348_V	0.529	0.99
20_Y	23_A	0.528	0.99
204_E	208_F	0.528	0.99
62_A	113_F	0.525	0.99
338_T	344_G	0.524	0.99
243_R	248_M	0.522	0.99
346_D	349_A	0.520	0.99
150_L	156_E	0.518	0.99
165_L	171_R	0.517	0.99
221_W	225_M	0.517	0.99
250_I	253_D	0.517	0.99
16_S	31_V	0.515	0.99
252_L	256_D	0.514	0.99
333_G	343_E	0.513	0.99
331_T	353_G	0.512	0.99
79_A	216_A	0.512	0.99
216_A	225_M	0.512	0.99
385_A	388_N	0.510	0.99
44_L	130_A	0.510	0.99
284_T	288_G	0.510	0.99
210_D	214_D	0.508	0.99
309_T	313_P	0.508	0.99
61_V	351_R	0.508	0.99
277_E	285_E	0.508	0.99
43_R	46_P	0.506	0.99
185_D	188_A	0.505	0.99
162_Y	360_A	0.505	0.99
90_V	94_R	0.502	0.99
395_P	401_T	0.501	0.99
278_Y	284_T	0.500	0.99

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
4k22A	4	0.7424	100	0.431	Contact Map
4n9xA	5	0.786	100	0.437	Contact Map
4bjzA	2	0.8122	100	0.44	Contact Map
3rp8A	1	0.81	100	0.443	Contact Map
1pn0A	3	0.8646	100	0.443	Contact Map
2qa1A	2	0.8406	100	0.444	Contact Map
2qa2A	2	0.8515	100	0.447	Contact Map
2x3nA	1	0.7555	100	0.45	Contact Map
3c96A	1	0.7882	100	0.452	Contact Map
4k5sA	2	0.8428	100	0.455	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.0105 seconds.