GREMLIN Database
HUTU - Probable urocanate hydratase
UniProt: Q9HQD8 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 588 (542)
Sequences: 1205 (343)
Seq/√Len: 14.7

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
33_G36_Q4.8261.00
54_D57_N4.8051.00
215_D219_E3.9621.00
197_V202_G3.8931.00
223_C250_G3.7821.00
457_D542_A3.7381.00
225_E236_R3.6530.99
395_R460_E3.6460.99
499_I515_V3.3940.99
395_R455_L3.3700.99
165_L271_V3.3470.99
136_I494_V3.2800.99
305_A309_A3.1640.98
297_E301_E3.1440.98
70_S73_A3.1380.98
221_G422_Q3.0930.98
155_I421_V3.0920.98
80_E100_V3.0880.98
461_I465_I3.0680.98
126_Q129_E2.9180.97
177_R244_G2.8790.97
182_A259_L2.8390.97
257_D288_S2.8090.97
32_E85_A2.7910.96
231_G265_R2.7750.96
240_A247_Y2.7270.96
323_A327_A2.7210.96
211_E215_D2.7110.96
99_G558_I2.6650.95
205_I237_A2.5980.95
261_G264_D2.5720.94
40_L78_L2.5620.94
261_G265_R2.5250.94
44_N78_L2.4960.93
305_A308_E2.4880.93
113_A116_N2.4820.93
232_E236_R2.4450.93
495_A527_L2.4350.92
508_A551_T2.4330.92
260_E316_R2.3950.92
182_A324_M2.3790.91
35_R511_D2.3700.91
227_T236_R2.3410.91
455_L461_I2.3330.91
25_T50_E2.3320.91
239_A243_A2.3300.91
215_D226_R2.3040.90
399_A451_R2.2980.90
457_D539_D2.2390.89
338_I362_F2.2380.89
184_A255_A2.1970.88
151_T155_I2.1820.87
129_E133_E2.1630.87
180_I267_F2.1590.87
407_K444_E2.1520.87
71_W74_Y2.1030.85
106_R543_E2.0890.85
211_E226_R2.0720.84
197_V204_C2.0720.84
36_Q39_A2.0610.84
302_D305_A2.0360.83
169_H330_V2.0330.83
394_H418_Q2.0160.83
358_D361_D2.0140.83
22_G25_T2.0130.83
76_A79_D2.0100.83
19_A75_D2.0010.82
203_V249_V1.9920.82
286_Y295_A1.9870.82
83_T578_T1.9840.82
180_I237_A1.9810.82
272_V331_A1.9490.80
315_A347_G1.9410.80
474_A557_V1.9360.80
21_R74_Y1.9280.80
389_N462_E1.9210.79
126_Q494_V1.9140.79
226_R252_H1.8870.78
448_F452_I1.8760.78
166_A202_G1.8730.78
533_V545_A1.8710.78
43_L78_L1.8660.77
319_A323_A1.8590.77
323_A326_D1.8580.77
151_T421_V1.8560.77
164_E167_R1.8370.76
101_F554_G1.8270.76
455_L460_E1.8270.76
391_A394_H1.8230.76
454_E458_N1.7930.74
535_L545_A1.7920.74
207_A259_L1.7830.74
33_G39_A1.7750.74
40_L44_N1.7740.74
164_E168_D1.7700.73
540_A544_T1.7670.73
260_E264_D1.7670.73
237_A249_V1.7480.73
101_F504_L1.7390.72
251_V258_V1.7270.72
86_D105_E1.7260.72
290_Y309_A1.7170.71
515_V527_L1.7160.71
214_I252_H1.7130.71
263_L323_A1.6910.70
401_T415_D1.6850.70
311_M341_Q1.6790.69
321_V331_A1.6720.69
180_I205_I1.6710.69
203_V237_A1.6660.69
208_E252_H1.6540.68
207_A253_G1.6520.68
30_E82_R1.6400.67
309_A312_D1.6220.67
92_V146_W1.6170.66
450_V542_A1.6110.66
567_D570_V1.6090.66
263_L327_A1.6060.66
390_P427_P1.5940.65
502_A515_V1.5860.65
126_Q136_I1.5800.64
395_R458_N1.5680.64
326_D358_D1.5550.63
207_A258_V1.5390.62
229_D232_E1.5350.62
104_H107_A1.5340.62
186_L208_E1.5330.62
227_T233_A1.5330.62
399_A455_L1.5290.62
211_E228_D1.5270.62
19_A74_Y1.5250.62
64_T523_I1.5230.62
259_L317_H1.5180.61
365_F472_L1.5150.61
123_D126_Q1.5140.61
180_I241_A1.5090.61
401_T414_I1.5020.60
398_R418_Q1.4960.60
531_N545_A1.4940.60
116_N499_I1.4920.60
186_L223_C1.4840.59
322_L347_G1.4700.59
225_E232_E1.4660.58
209_V286_Y1.4660.58
80_E90_L1.4500.58
504_L555_M1.4400.57
521_V526_S1.4370.57
324_M331_A1.4340.57
33_G86_D1.4290.56
198_T224_M1.4170.56
117_L130_L1.3930.54
543_E546_R1.3920.54
53_E188_G1.3870.54
288_S316_R1.3830.54
38_A534_V1.3800.54
116_N527_L1.3760.54
400_V448_F1.3720.53
446_A550_T1.3650.53
181_V271_V1.3570.52
205_I262_M1.3540.52
263_L324_M1.3540.52
194_P206_A1.3460.52
340_G344_A1.3450.52
238_T241_A1.3440.52
177_R201_H1.3410.52
166_A176_L1.3400.52
236_R247_Y1.3370.51
39_A511_D1.3170.50
129_E132_A1.3120.50
398_R402_E1.3120.50
234_I262_M1.3090.50
508_A533_V1.3060.50
105_E540_A1.2980.49
503_L506_T1.2960.49
214_I226_R1.2920.49
237_A258_V1.2890.49
555_M558_I1.2890.49
343_A357_H1.2760.48
106_R540_A1.2750.48
281_E314_M1.2740.48
194_P248_S1.2630.47
186_L252_H1.2630.47
234_I258_V1.2620.47
147_A468_T1.2460.46
23_A426_L1.2400.46
116_N515_V1.2340.46
281_E341_Q1.2290.45
404_F448_F1.2250.45
568_A572_A1.2200.45
210_D213_R1.2130.44
175_G201_H1.2120.44
341_Q344_A1.2090.44
120_N525_N1.2040.44
66_Q131_E1.2030.44
166_A175_G1.1980.44
122_A517_N1.1970.44
247_Y291_T1.1960.44
236_R245_D1.1920.43
64_T131_E1.1870.43
176_L202_G1.1850.43
272_V324_M1.1840.43
539_D543_E1.1810.43
101_F558_I1.1750.42
163_A200_N1.1580.41
68_A77_I1.1570.41
41_R426_L1.1530.41
474_A555_M1.1510.41
207_A260_E1.1390.40
85_A100_V1.1320.40
362_F368_A1.1300.40
79_D83_T1.1280.40
128_H131_E1.1270.40
510_A513_V1.1250.40
540_A543_E1.1200.39
84_L100_V1.1200.39
384_V428_S1.1140.39
21_R44_N1.1050.39
24_P44_N1.0950.38
198_T204_C1.0920.38
131_E523_I1.0910.38
205_I229_D1.0860.38
395_R461_I1.0850.38
291_T294_D1.0850.38
228_D232_E1.0770.37
247_Y420_H1.0700.37
93_Q500_L1.0590.36
216_R219_E1.0520.36
263_L268_V1.0490.36
414_I452_I1.0370.35
73_A96_K1.0340.35
197_V203_V1.0340.35
456_V461_I1.0320.35
571_E575_S1.0260.35
181_V197_V1.0250.35
183_T206_A1.0220.34
539_D542_A1.0190.34
74_Y465_I1.0170.34
321_V362_F1.0070.34
31_C82_R1.0060.34
259_L272_V1.0040.33
181_V202_G1.0000.33
308_E312_D0.9990.33
238_T242_E0.9960.33
455_L458_N0.9940.33
268_V324_M0.9920.33
403_L451_R0.9920.33
44_N74_Y0.9920.33
401_T411_H0.9890.33
117_L123_D0.9880.33
308_E539_D0.9830.32
182_A262_M0.9830.32
214_I250_G0.9820.32
36_Q86_D0.9780.32
138_Y526_S0.9760.32
340_G525_N0.9760.32
452_I467_V0.9740.32
85_A88_E0.9730.32
71_W78_L0.9730.32
207_A256_A0.9720.32
343_A358_D0.9710.32
54_D59_V0.9710.32
231_G261_G0.9680.32
74_Y78_L0.9680.32
391_A462_E0.9670.32
542_A546_R0.9640.32
257_D289_G0.9630.31
205_I249_V0.9590.31
31_C37_E0.9590.31
372_P375_C0.9590.31
295_A306_Y0.9570.31
399_A452_I0.9550.31
207_A272_V0.9550.31
416_L419_E0.9540.31
344_A525_N0.9520.31
87_A105_E0.9470.31
504_L558_I0.9460.31
136_I523_I0.9460.31
225_E247_Y0.9460.31
120_N123_D0.9450.31
218_I226_R0.9400.30
198_T420_H0.9350.30
34_W37_E0.9320.30
454_E460_E0.9290.30
126_Q133_E0.9250.30
64_T128_H0.9240.30
179_K270_D0.9240.30
36_Q511_D0.9230.30
488_R566_A0.9210.30
229_D236_R0.9150.29
231_G534_V0.9120.29
197_V201_H0.9080.29
201_H246_P0.9080.29
166_A515_V0.9060.29
474_A571_E0.9010.29
395_R462_E0.8970.28
499_I527_L0.8940.28
80_E83_T0.8930.28
227_T232_E0.8890.28
116_N495_A0.8860.28
40_L43_L0.8820.28
66_Q231_G0.8810.28
340_G481_N0.8800.28
255_A338_I0.8790.28
166_A200_N0.8790.28
386_L466_V0.8790.28
180_I203_V0.8730.27
182_A272_V0.8720.27
77_I90_L0.8710.27
319_A347_G0.8690.27
139_G520_G0.8670.27
454_E542_A0.8650.27
21_R71_W0.8630.27
211_E252_H0.8620.27
175_G200_N0.8610.27
165_L170_Y0.8600.27
87_A102_E0.8590.27
234_I261_G0.8580.27
286_Y296_D0.8570.27
183_T204_C0.8570.27
144_G333_E0.8560.27
318_V338_I0.8550.27
96_K562_D0.8540.26
115_S136_I0.8460.26
155_I216_R0.8410.26
414_I527_L0.8400.26
257_D260_E0.8400.26
103_T504_L0.8370.26
246_P420_H0.8370.26
194_P456_V0.8360.26
221_G419_E0.8360.26
88_E100_V0.8330.26
259_L331_A0.8320.26
39_A512_I0.8310.26
268_V329_A0.8300.25
182_A255_A0.8280.25
450_V457_D0.8280.25
363_P368_A0.8280.25
166_A179_K0.8270.25
40_L82_R0.8240.25
310_S315_A0.8230.25
262_M269_P0.8220.25
42_M466_V0.8200.25
106_R544_T0.8190.25
102_E546_R0.8190.25
197_V200_N0.8180.25
263_L320_A0.8180.25
63_G109_S0.8170.25
141_M479_S0.8160.25
33_G511_D0.8160.25
399_A403_L0.8150.25
104_H544_T0.8120.25
34_W41_R0.8110.25
26_G34_W0.8110.25
395_R399_A0.8100.25
225_E239_A0.8080.25
257_D316_R0.8070.25
561_A569_L0.8050.24
307_R311_M0.8040.24
257_D262_M0.8030.24
395_R398_R0.7990.24
111_L502_A0.7950.24
294_D297_E0.7920.24
24_P30_E0.7900.24
393_I423_F0.7870.24
499_I502_A0.7860.24
290_Y297_E0.7860.24
194_P223_C0.7820.23
213_R277_S0.7820.23
451_R454_E0.7810.23
171_P174_D0.7810.23
402_E539_D0.7800.23
449_A549_F0.7770.23
78_L82_R0.7750.23
128_H132_A0.7750.23
131_E494_V0.7730.23
561_A579_V0.7700.23
169_H332_F0.7700.23
288_S320_A0.7680.23
384_V566_A0.7670.23
155_I338_I0.7640.23
52_A62_G0.7630.23
458_N461_I0.7620.23
203_V247_Y0.7620.23
297_E302_D0.7610.23
230_L251_V0.7600.23
31_C36_Q0.7600.23
100_V363_P0.7590.23
258_V261_G0.7580.23
399_A448_F0.7570.23
411_H415_D0.7570.23
396_T452_I0.7550.22
337_N525_N0.7530.22
31_C40_L0.7530.22
114_N144_G0.7520.22
211_E292_V0.7520.22
313_T407_K0.7470.22
298_L465_I0.7460.22
479_S521_V0.7450.22
228_D236_R0.7430.22
334_Y482_R0.7430.22
145_S514_S0.7430.22
256_A260_E0.7420.22
113_A527_L0.7420.22
66_Q128_H0.7420.22
230_L234_I0.7410.22
488_R569_L0.7400.22
391_A395_R0.7400.22
50_E219_E0.7390.22
184_A204_C0.7380.22
503_L515_V0.7370.22
286_Y306_Y0.7370.22
236_R249_V0.7340.22
31_C208_E0.7340.22
138_Y499_I0.7320.22
277_S362_F0.7320.22
221_G420_H0.7310.22
558_I577_V0.7270.21
179_K197_V0.7250.21
295_A299_R0.7250.21
151_T338_I0.7250.21
174_D408_D0.7200.21
334_Y483_E0.7200.21
571_E574_A0.7180.21
268_V327_A0.7180.21
567_D571_E0.7160.21
219_E226_R0.7160.21
289_G312_D0.7150.21
495_A523_I0.7140.21
119_G495_A0.7140.21
223_C252_H0.7130.21
312_D570_V0.7130.21
395_R451_R0.7120.21
365_F432_W0.7100.21
219_E398_R0.7070.21
37_E41_R0.7040.21
575_S578_T0.7030.20
208_E533_V0.7020.20
80_E578_T0.7010.20
446_A450_V0.6990.20
302_D308_E0.6980.20
165_L263_L0.6980.20
182_A370_I0.6960.20
162_L506_T0.6950.20
375_C468_T0.6950.20
315_A319_A0.6940.20
414_I554_G0.6930.20
310_S314_M0.6930.20
145_S512_I0.6930.20
177_R243_A0.6920.20
427_P485_E0.6910.20
400_V407_K0.6900.20
106_R533_V0.6890.20
260_E313_T0.6860.20
30_E40_L0.6860.20
538_S542_A0.6850.20
169_H544_T0.6840.20
298_L305_A0.6840.20
56_E257_D0.6830.20
59_V514_S0.6830.20
171_P574_A0.6820.20
209_V258_V0.6810.20
225_E229_D0.6790.20
372_P376_R0.6790.20
290_Y298_L0.6790.20
35_R534_V0.6780.20
113_A256_A0.6780.20
220_T422_Q0.6760.20
237_A241_A0.6760.20
450_V454_E0.6760.20
288_S313_T0.6760.20
378_K474_A0.6710.19
232_E249_V0.6700.19
129_E357_H0.6690.19
332_F515_V0.6680.19
186_L214_I0.6680.19
482_R522_G0.6670.19
105_E506_T0.6670.19
272_V320_A0.6670.19
403_L448_F0.6670.19
403_L411_H0.6670.19
365_F375_C0.6670.19
235_E309_A0.6650.19
99_G555_M0.6650.19
256_A272_V0.6640.19
259_L324_M0.6630.19
505_N548_V0.6630.19
66_Q75_D0.6620.19
404_F444_E0.6610.19
234_I263_L0.6610.19
174_D304_D0.6610.19
62_G65_G0.6610.19
325_Q329_A0.6600.19
230_L534_V0.6600.19
202_G237_A0.6590.19
87_A566_A0.6590.19
165_L369_Y0.6580.19
206_A214_I0.6570.19
318_V342_V0.6540.19
64_T136_I0.6540.19
232_E402_E0.6540.19
73_A208_E0.6520.19
60_V67_A0.6500.19
299_R306_Y0.6500.19
144_G516_H0.6500.19
223_C452_I0.6480.19
533_V538_S0.6480.19
447_R455_L0.6470.19
207_A251_V0.6470.19
511_D527_L0.6470.19
184_A207_A0.6470.19
316_R319_A0.6460.18
462_E465_I0.6460.18
66_Q70_S0.6460.18
297_E308_E0.6450.18
535_L542_A0.6450.18
334_Y522_G0.6450.18
450_V546_R0.6430.18
57_N188_G0.6430.18
243_A465_I0.6430.18
175_G179_K0.6420.18
161_T483_E0.6420.18
119_G186_L0.6420.18
92_V302_D0.6420.18
18_Q21_R0.6410.18
177_R242_E0.6410.18
207_A320_A0.6410.18
207_A384_V0.6400.18
511_D534_V0.6400.18
29_I40_L0.6400.18
234_I320_A0.6390.18
340_G343_A0.6380.18
282_L307_R0.6360.18
234_I241_A0.6340.18
59_V267_F0.6330.18
103_T508_A0.6330.18
400_V451_R0.6310.18
107_A521_V0.6300.18
166_A197_V0.6280.18
479_S482_R0.6270.18
62_G140_Q0.6270.18
250_G564_G0.6250.18
181_V273_T0.6250.18
378_K508_A0.6240.18
169_H337_N0.6220.18
217_R430_V0.6220.18
105_E544_T0.6220.18
113_A499_I0.6210.18
298_L306_Y0.6190.18
70_S96_K0.6180.18
225_E245_D0.6180.18
403_L406_E0.6170.18
378_K448_F0.6170.18
208_E343_A0.6170.18
414_I448_F0.6170.18
161_T334_Y0.6170.18
207_A244_G0.6170.18
33_G84_L0.6160.18
405_P415_D0.6160.18
277_S333_E0.6150.17
277_S396_T0.6130.17
91_L514_S0.6130.17
199_M259_L0.6120.17
304_D312_D0.6120.17
170_Y330_V0.6120.17
214_I218_I0.6090.17
177_R245_D0.6090.17
184_A538_S0.6080.17
182_A331_A0.6080.17
340_G345_H0.6070.17
449_A531_N0.6060.17
504_L551_T0.6040.17
44_N372_P0.6040.17
372_P563_A0.6040.17
99_G448_F0.6040.17
255_A259_L0.6040.17
319_A570_V0.6040.17
165_L465_I0.6030.17
256_A320_A0.6010.17
147_A372_P0.6010.17
314_M338_I0.6000.17
36_Q40_L0.5990.17
23_A41_R0.5990.17
169_H369_Y0.5970.17
124_W500_L0.5970.17
452_I511_D0.5970.17
230_L262_M0.5970.17
305_A319_A0.5970.17
236_R239_A0.5960.17
59_V296_D0.5960.17
98_V485_E0.5960.17
306_Y337_N0.5950.17
35_R86_D0.5950.17
476_S560_H0.5930.17
130_L493_A0.5930.17
332_F456_V0.5930.17
197_V452_I0.5920.17
485_E500_L0.5920.17
121_W493_A0.5910.17
170_Y271_V0.5910.17
147_A532_H0.5900.17
233_A251_V0.5890.17
403_L452_I0.5890.17
432_W472_L0.5890.17
408_D415_D0.5880.17
179_K202_G0.5870.17
197_V206_A0.5860.17
59_V116_N0.5860.17
474_A504_L0.5850.17
44_N71_W0.5840.17
28_D183_T0.5840.17
168_D368_A0.5840.17
250_G324_M0.5840.17
59_V64_T0.5840.17
286_Y299_R0.5830.16
384_V468_T0.5820.16
99_G277_S0.5820.16
141_M154_I0.5820.16
399_A405_P0.5810.16
263_L312_D0.5810.16
405_P411_H0.5810.16
101_F461_I0.5800.16
403_L447_R0.5800.16
182_A234_I0.5790.16
228_D252_H0.5790.16
566_A570_V0.5790.16
141_M482_R0.5790.16
205_I246_P0.5770.16
385_A393_I0.5770.16
180_I204_C0.5770.16
119_G517_N0.5770.16
414_I495_A0.5760.16
87_A488_R0.5760.16
283_A299_R0.5750.16
421_V444_E0.5750.16
331_A362_F0.5750.16
39_A534_V0.5740.16
208_E226_R0.5740.16
209_V295_A0.5730.16
499_I503_L0.5710.16
266_D418_Q0.5710.16
154_I482_R0.5710.16
227_T251_V0.5700.16
232_E245_D0.5690.16
92_V112_I0.5690.16
249_V405_P0.5690.16
188_G277_S0.5660.16
481_N525_N0.5650.16
315_A461_I0.5650.16
260_E320_A0.5650.16
98_V515_V0.5640.16
277_S284_G0.5640.16
101_F400_V0.5630.16
125_E357_H0.5630.16
170_Y329_A0.5630.16
69_R74_Y0.5620.16
223_C226_R0.5620.16
155_I422_Q0.5610.16
467_V549_F0.5610.16
109_S140_Q0.5600.16
140_Q528_H0.5600.16
495_A554_G0.5590.16
183_T208_E0.5570.16
245_D419_E0.5570.16
236_R243_A0.5560.16
230_L265_R0.5560.16
512_I532_H0.5560.16
83_T100_V0.5560.16
207_A317_H0.5550.16
63_G145_S0.5550.16
182_A237_A0.5550.16
468_T532_H0.5540.16
35_R540_A0.5530.16
260_E263_L0.5530.16
23_A48_D0.5520.16
402_E574_A0.5520.16
444_E448_F0.5510.16
22_G570_V0.5500.15
225_E231_G0.5500.15
92_V107_A0.5500.15
64_T283_A0.5500.15
24_P78_L0.5500.15
140_Q522_G0.5490.15
237_A448_F0.5490.15
377_G483_E0.5480.15
364_G560_H0.5470.15
70_S229_D0.5470.15
127_F332_F0.5470.15
131_E136_I0.5470.15
175_G197_V0.5460.15
211_E229_D0.5460.15
447_R461_I0.5460.15
241_A315_A0.5460.15
212_A538_S0.5450.15
184_A259_L0.5440.15
555_M579_V0.5430.15
277_S430_V0.5420.15
495_A515_V0.5420.15
256_A261_G0.5420.15
216_R515_V0.5420.15
305_A447_R0.5410.15
27_T546_R0.5410.15
85_A208_E0.5410.15
396_T403_L0.5410.15
164_E531_N0.5400.15
317_H321_V0.5400.15
147_A375_C0.5390.15
234_I265_R0.5390.15
203_V415_D0.5380.15
308_E566_A0.5380.15
242_E312_D0.5380.15
298_L357_H0.5360.15
225_E308_E0.5360.15
141_M334_Y0.5360.15
205_I233_A0.5350.15
236_R240_A0.5340.15
239_A298_L0.5340.15
367_P532_H0.5330.15
245_D264_D0.5310.15
144_G532_H0.5310.15
466_V512_I0.5300.15
162_L432_W0.5290.15
449_A467_V0.5280.15
33_G41_R0.5280.15
240_A303_P0.5270.15
50_E123_D0.5270.15
327_A357_H0.5270.15
327_A398_R0.5270.15
128_H494_V0.5260.15
471_H482_R0.5260.15
171_P557_V0.5260.15
130_L222_Y0.5250.15
250_G538_S0.5250.15
553_P560_H0.5250.15
182_A199_M0.5250.15
30_E44_N0.5250.15
52_A63_G0.5250.15
137_M145_S0.5240.15
229_D543_E0.5240.15
231_G234_I0.5240.15
136_I563_A0.5240.15
199_M255_A0.5220.15
32_E283_A0.5220.15
151_T314_M0.5220.15
86_D168_D0.5220.15
177_R235_E0.5210.15
176_L203_V0.5210.15
230_L320_A0.5200.15
297_E458_N0.5200.15
38_A230_L0.5200.15
57_N221_G0.5200.15
375_C472_L0.5190.15
141_M522_G0.5190.15
64_T341_Q0.5190.15
305_A574_A0.5190.15
20_Y50_E0.5180.15
243_A566_A0.5170.15
268_V462_E0.5170.15
79_D539_D0.5170.15
46_N141_M0.5170.15
329_A401_T0.5170.15
197_V237_A0.5160.15
239_A304_D0.5160.15
39_A112_I0.5160.15
269_P299_R0.5160.15
181_V237_A0.5150.14
235_E239_A0.5150.14
269_P337_N0.5150.14
235_E297_E0.5140.14
186_L226_R0.5140.14
318_V362_F0.5140.14
167_R171_P0.5140.14
22_G177_R0.5130.14
463_A466_V0.5130.14
457_D538_S0.5130.14
280_D475_G0.5130.14
154_I396_T0.5120.14
52_A431_C0.5110.14
370_I545_A0.5110.14
228_D231_G0.5110.14
237_A262_M0.5100.14
400_V418_Q0.5100.14
84_L87_A0.5090.14
253_G320_A0.5090.14
210_D271_V0.5080.14
504_L578_T0.5080.14
291_T481_N0.5080.14
105_E391_A0.5080.14
35_R243_A0.5070.14
35_R533_V0.5070.14
115_S568_A0.5060.14
235_E546_R0.5060.14
399_A414_I0.5050.14
329_A495_A0.5050.14
145_S333_E0.5050.14
404_F457_D0.5050.14
225_E228_D0.5040.14
482_R509_G0.5040.14
184_A344_A0.5040.14
225_E243_A0.5040.14
545_A549_F0.5030.14
297_E457_D0.5030.14
208_E214_I0.5030.14
129_E136_I0.5020.14
271_V294_D0.5020.14
89_T254_N0.5020.14
200_N452_I0.5020.14
101_F448_F0.5010.14
29_I82_R0.5010.14
54_D188_G0.5010.14
206_A226_R0.5010.14
59_V212_A0.5010.14
239_A428_S0.5000.14
297_E300_D0.5000.14
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
1x87A 2 0.869 100 0.056 Contact Map
1uwkA 2 0.9422 100 0.057 Contact Map
2fknA 2 0.9286 100 0.057 Contact Map
3p2yA 2 0.4983 75.2 0.985 Contact Map
4mhbA 4 0.4269 63.5 0.986 Contact Map
3wbwA 1 0.4082 62.1 0.986 Contact Map
1l7dA 2 0.5221 57.9 0.987 Contact Map
3oj0A 1 0.2296 55.4 0.987 Contact Map
1hw6A 1 0.381 53.3 0.987 Contact Map
3d4oA 4 0.4762 52.5 0.987 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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