Q9HQ81 - HALSA - GREMLIN Contacts

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Q9HQ81 - TRK potassium uptake system protein

UniProt:	Q9HQ81	Sequences: MVDRLGTIARDLGRMLEALAGLIFVSVLVPLVWGEFWVVPAMVVSGLIPLVVGLTLRRTFEHAADPGRLHGMMIAASGWFLVAAFGSVPFLLAAWTAQLDPGMLDVPARFTVPGTRTFSTLAAFQNPLNGFFESMSGFTGTGLTMADNEAALPHTLQWWRSFIEWVGGVGVIVLTTAILARPGSGSLTLYESEARSEKIHPSIVSTVRTIWWIFLLFTFFSILLLWIAGMPMWDAINHAMTGLATGGFSITDNSIATYGSAAIDFALIPVMVLGSIAFPIHYLVLQGDLRNLYTDLQTRWVFGFFALGTALLTAVLLQQGYYVTESVAVAGVVLHGSAATLFQTVRYALFQFVSAASCTGFQTAGALGSGWTAPAQLTVAFGMVVGAAAGSTVGGIKLIRLLTLVKGILFRIRGVFYPSDAVRTFRLDGRALSDTEAAQEFEEAAIITFLWLVFLGVAAFVFMLAIPMGPDAYTVENVLFEVASAQGNVGLSSGITGPGMPTVTKAMFLFNMWIGRLEIIPVLVLLRGLFSTLEVYD	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	537 (381)
Sequences:	5053 (3728)
Seq/√Len:	191.0

ECOLI - TRKG TRKH
BACSU - KTRB KTRD
HALSA - Q9HQ81 Q9HMF7 Q9HPA9

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
387_A	393_V	4.174	1.00
458_A	511_N	4.090	1.00
129_N	505_K	3.607	1.00
268_I	349_L	3.414	1.00
128_L	506_A	3.330	1.00
222_I	236_I	3.326	1.00
225_L	267_L	3.299	1.00
221_S	270_V	3.060	1.00
165_W	218_T	2.957	1.00
461_V	507_M	2.884	1.00
228_A	260_S	2.693	1.00
253_N	257_T	2.604	1.00
251_T	257_T	2.580	1.00
365_G	370_G	2.567	1.00
228_A	262_A	2.529	1.00
164_E	241_T	2.485	1.00
161_S	237_N	2.457	1.00
474_T	477_N	2.445	1.00
131_F	509_L	2.395	1.00
224_L	266_A	2.372	1.00
340_T	343_Q	2.358	1.00
388_A	398_L	2.298	1.00
462_F	504_T	2.231	1.00
226_W	232_M	2.217	1.00
157_Q	233_W	2.189	1.00
135_M	509_L	2.167	1.00
228_A	266_A	2.157	1.00
241_T	361_F	2.122	1.00
154_H	158_W	2.100	1.00
355_A	379_V	2.098	1.00
459_A	479_L	2.085	1.00
228_A	263_I	2.075	1.00
128_L	509_L	2.071	1.00
238_H	249_S	2.054	1.00
264_D	346_R	2.044	1.00
222_I	232_M	2.044	1.00
264_D	347_Y	2.024	1.00
125_Q	151_A	1.986	1.00
275_S	357_S	1.984	1.00
147_D	150_A	1.971	1.00
268_I	353_V	1.909	1.00
155_T	159_W	1.907	1.00
404_L	448_T	1.859	1.00
126_N	129_N	1.850	1.00
243_L	274_G	1.847	1.00
255_I	267_L	1.838	1.00
275_S	301_V	1.835	1.00
128_L	502_T	1.805	1.00
342_F	346_R	1.803	1.00
226_W	235_A	1.761	1.00
261_A	346_R	1.761	1.00
455_L	483_A	1.747	1.00
365_G	369_S	1.736	1.00
272_V	353_V	1.728	1.00
265_F	269_P	1.725	1.00
144_T	148_N	1.724	1.00
481_E	496_T	1.713	1.00
224_L	262_A	1.701	1.00
380_A	483_A	1.697	1.00
262_A	266_A	1.697	1.00
403_T	432_L	1.687	1.00
458_A	507_M	1.651	1.00
264_D	363_T	1.651	1.00
484_S	489_V	1.645	1.00
265_F	346_R	1.642	1.00
461_V	503_V	1.620	1.00
148_N	151_A	1.619	1.00
125_Q	152_L	1.605	1.00
409_L	413_R	1.576	1.00
358_C	489_V	1.572	1.00
135_M	513_W	1.561	1.00
455_L	486_Q	1.544	1.00
222_I	239_A	1.540	1.00
385_V	398_L	1.533	1.00
396_I	401_L	1.529	1.00
265_F	342_F	1.528	1.00
136_S	248_F	1.525	1.00
242_G	267_L	1.507	1.00
237_N	250_I	1.496	1.00
208_R	212_W	1.494	1.00
271_M	354_S	1.479	1.00
471_D	501_P	1.478	1.00
230_M	263_I	1.467	1.00
224_L	228_A	1.463	1.00
234_D	251_T	1.460	1.00
271_M	359_T	1.444	1.00
164_E	246_G	1.444	1.00
313_T	317_L	1.441	1.00
477_N	493_S	1.440	1.00
251_T	258_Y	1.439	1.00
157_Q	161_S	1.437	1.00
133_E	145_M	1.437	1.00
127_P	131_F	1.434	1.00
259_G	347_Y	1.424	1.00
506_A	510_F	1.422	1.00
265_F	349_L	1.420	1.00
149_E	252_D	1.408	1.00
310_A	314_A	1.399	1.00
352_F	355_A	1.399	1.00
473_Y	495_I	1.396	1.00
131_F	506_A	1.392	1.00
492_S	496_T	1.392	1.00
309_T	313_T	1.388	1.00
459_A	482_V	1.387	1.00
458_A	482_V	1.383	1.00
269_P	273_L	1.379	1.00
366_A	379_V	1.373	1.00
128_L	505_K	1.367	1.00
403_T	437_A	1.362	1.00
314_A	317_L	1.352	1.00
451_W	486_Q	1.342	1.00
230_M	234_D	1.342	1.00
380_A	479_L	1.339	1.00
424_T	431_A	1.325	1.00
90_F	163_I	1.316	1.00
238_H	250_I	1.303	1.00
232_M	236_I	1.302	1.00
148_N	252_D	1.293	1.00
204_V	208_R	1.292	1.00
311_L	315_V	1.292	1.00
506_A	509_L	1.286	1.00
137_G	248_F	1.281	1.00
265_F	345_V	1.280	1.00
225_L	263_I	1.278	1.00
134_S	163_I	1.277	1.00
381_F	385_V	1.277	1.00
376_Q	493_S	1.272	1.00
253_N	256_A	1.267	1.00
473_Y	478_V	1.263	1.00
351_Q	363_T	1.261	1.00
154_H	233_W	1.254	1.00
272_V	302_F	1.250	1.00
495_I	499_G	1.248	1.00
300_W	402_L	1.233	1.00
147_D	252_D	1.229	1.00
221_S	239_A	1.226	1.00
131_F	135_M	1.222	1.00
312_L	402_L	1.222	1.00
226_W	231_P	1.219	1.00
343_Q	347_Y	1.215	1.00
317_L	353_V	1.215	1.00
366_A	371_W	1.214	1.00
242_G	361_F	1.211	1.00
261_A	264_D	1.202	1.00
500_M	508_F	1.195	1.00
283_L	303_G	1.191	1.00
510_F	514_I	1.189	1.00
242_G	270_V	1.177	1.00
384_V	455_L	1.168	1.00
347_Y	351_Q	1.166	1.00
256_A	362_Q	1.163	1.00
385_V	401_L	1.158	1.00
347_Y	364_A	1.155	1.00
152_L	160_R	1.153	1.00
482_V	511_N	1.153	1.00
129_N	145_M	1.149	1.00
341_L	345_V	1.145	1.00
455_L	459_A	1.143	1.00
264_D	268_I	1.143	1.00
380_A	480_F	1.131	1.00
161_S	236_I	1.131	1.00
272_V	305_F	1.128	1.00
158_W	162_F	1.116	1.00
217_F	281_H	1.109	1.00
161_S	233_W	1.108	1.00
471_D	504_T	1.102	1.00
126_N	502_T	1.094	1.00
221_S	267_L	1.094	1.00
259_G	264_D	1.092	1.00
218_T	239_A	1.092	1.00
249_S	254_S	1.090	1.00
256_A	365_G	1.087	1.00
372_T	375_A	1.085	1.00
434_D	438_A	1.080	1.00
310_A	313_T	1.073	1.00
91_L	127_P	1.072	1.00
347_Y	363_T	1.071	1.00
265_F	268_I	1.064	1.00
309_T	349_L	1.060	1.00
217_F	273_L	1.058	1.00
407_G	445_A	1.050	1.00
261_A	265_F	1.050	1.00
161_S	240_M	1.050	1.00
231_P	235_A	1.046	1.00
223_L	227_I	1.046	1.00
462_F	508_F	1.046	1.00
271_M	353_V	1.045	1.00
366_A	493_S	1.042	1.00
389_A	399_I	1.040	1.00
463_M	478_V	1.036	1.00
471_D	503_V	1.034	1.00
221_S	225_L	1.034	1.00
154_H	157_Q	1.033	1.00
302_F	306_A	1.031	1.00
290_R	294_T	1.029	1.00
125_Q	146_A	1.020	1.00
261_A	342_F	1.018	1.00
500_M	504_T	1.014	1.00
135_M	522_V	1.013	1.00
225_L	242_G	0.999	1.00
169_V	211_W	0.991	0.99
146_A	152_L	0.991	0.99
315_V	319_Q	0.989	0.99
133_E	148_N	0.988	0.99
221_S	242_G	0.986	0.99
485_A	508_F	0.985	0.99
296_L	428_D	0.983	0.99
221_S	266_A	0.978	0.99
403_T	444_A	0.976	0.99
383_M	489_V	0.971	0.99
501_P	504_T	0.971	0.99
295_D	428_D	0.966	0.99
411_R	438_A	0.965	0.99
376_Q	477_N	0.964	0.99
462_F	482_V	0.964	0.99
133_E	160_R	0.962	0.99
158_W	233_W	0.962	0.99
145_M	148_N	0.956	0.99
260_S	263_I	0.955	0.99
339_A	347_Y	0.955	0.99
448_T	452_L	0.954	0.99
374_P	460_F	0.952	0.99
276_I	298_T	0.952	0.99
255_I	263_I	0.947	0.99
308_G	312_L	0.945	0.99
137_G	160_R	0.945	0.99
249_S	252_D	0.944	0.99
273_L	281_H	0.941	0.99
225_L	266_A	0.939	0.99
312_L	315_V	0.938	0.99
212_W	216_L	0.937	0.99
300_W	398_L	0.935	0.99
459_A	478_V	0.934	0.99
308_G	382_G	0.934	0.99
369_S	376_Q	0.929	0.99
259_G	339_A	0.928	0.99
405_V	409_L	0.926	0.99
289_L	293_Y	0.924	0.99
454_F	514_I	0.919	0.99
314_A	318_Q	0.918	0.99
355_A	491_L	0.917	0.99
504_T	508_F	0.916	0.99
352_F	382_G	0.915	0.99
225_L	255_I	0.915	0.99
227_I	262_A	0.915	0.99
331_G	337_S	0.913	0.99
238_H	251_T	0.913	0.99
406_K	425_F	0.912	0.99
389_A	398_L	0.907	0.99
503_V	507_M	0.904	0.99
315_V	375_A	0.899	0.99
481_E	492_S	0.898	0.99
148_N	152_L	0.898	0.99
231_P	234_D	0.895	0.99
482_V	508_F	0.895	0.99
250_I	258_Y	0.894	0.99
315_V	318_Q	0.892	0.99
378_T	460_F	0.892	0.99
484_S	492_S	0.891	0.99
150_A	252_D	0.887	0.99
217_F	243_L	0.885	0.99
313_T	348_A	0.882	0.99
339_A	344_T	0.879	0.99
161_S	164_E	0.874	0.99
366_A	369_S	0.874	0.99
95_W	153_P	0.874	0.99
164_E	244_A	0.869	0.99
280_I	298_T	0.857	0.98
289_L	292_L	0.854	0.98
127_P	506_A	0.849	0.98
143_L	484_S	0.849	0.98
454_F	511_N	0.849	0.98
288_D	291_N	0.842	0.98
304_F	308_G	0.842	0.98
138_F	163_I	0.842	0.98
311_L	428_D	0.840	0.98
202_S	205_S	0.839	0.98
351_Q	379_V	0.835	0.98
486_Q	511_N	0.833	0.98
373_A	476_E	0.829	0.98
223_L	226_W	0.828	0.98
148_N	160_R	0.824	0.98
161_S	241_T	0.824	0.98
96_T	125_Q	0.812	0.98
222_I	226_W	0.811	0.98
187_L	191_E	0.809	0.98
369_S	493_S	0.809	0.98
246_G	358_C	0.809	0.98
406_K	427_L	0.803	0.98
308_G	315_V	0.802	0.98
231_P	258_Y	0.802	0.98
383_M	484_S	0.802	0.98
483_A	487_G	0.802	0.98
219_F	223_L	0.800	0.98
451_W	487_G	0.800	0.98
408_I	446_I	0.797	0.98
174_L	211_W	0.794	0.97
384_V	451_W	0.792	0.97
93_A	156_L	0.786	0.97
281_H	292_L	0.786	0.97
306_A	310_A	0.786	0.97
153_P	156_L	0.785	0.97
450_L	520_I	0.773	0.97
205_S	208_R	0.770	0.97
332_V	337_S	0.768	0.97
209_T	282_Y	0.766	0.97
245_T	357_S	0.765	0.97
308_G	406_K	0.758	0.97
188_T	191_E	0.758	0.97
304_F	398_L	0.756	0.97
453_V	457_V	0.756	0.97
338_A	344_T	0.755	0.97
313_T	316_L	0.755	0.97
476_E	493_S	0.753	0.97
283_L	306_A	0.751	0.96
305_F	309_T	0.750	0.96
133_E	144_T	0.750	0.96
304_F	385_V	0.750	0.96
362_Q	491_L	0.749	0.96
459_A	475_V	0.748	0.96
380_A	476_E	0.746	0.96
499_G	502_T	0.743	0.96
292_L	298_T	0.741	0.96
307_L	311_L	0.739	0.96
245_T	392_T	0.739	0.96
237_N	241_T	0.738	0.96
496_T	500_M	0.737	0.96
404_L	449_F	0.735	0.96
306_A	309_T	0.733	0.96
410_F	434_D	0.733	0.96
341_L	344_T	0.732	0.96
298_T	302_F	0.730	0.96
309_T	312_L	0.730	0.96
408_I	450_L	0.728	0.96
213_I	217_F	0.727	0.96
91_L	94_A	0.726	0.96
268_I	272_V	0.725	0.96
480_F	491_L	0.723	0.96
214_F	244_A	0.721	0.96
290_R	293_Y	0.719	0.96
410_F	425_F	0.716	0.95
216_L	220_F	0.716	0.95
262_A	265_F	0.716	0.95
462_F	478_V	0.714	0.95
221_S	224_L	0.713	0.95
463_M	475_V	0.711	0.95
218_T	222_I	0.710	0.95
144_T	160_R	0.708	0.95
238_H	267_L	0.708	0.95
339_A	343_Q	0.706	0.95
234_D	238_H	0.703	0.95
351_Q	354_S	0.703	0.95
404_L	408_I	0.702	0.95
128_L	508_F	0.700	0.95
351_Q	366_A	0.699	0.95
255_I	258_Y	0.696	0.95
407_G	437_A	0.695	0.95
362_Q	365_G	0.694	0.95
164_E	240_M	0.694	0.95
275_S	387_A	0.694	0.95
404_L	445_A	0.692	0.94
245_T	274_G	0.691	0.94
150_A	251_T	0.688	0.94
238_H	361_F	0.687	0.94
396_I	448_T	0.680	0.94
229_G	233_W	0.679	0.94
192_S	195_R	0.679	0.94
90_F	156_L	0.674	0.94
307_L	428_D	0.674	0.94
143_L	485_A	0.671	0.94
281_H	285_L	0.669	0.93
233_W	237_N	0.668	0.93
377_L	475_V	0.666	0.93
272_V	313_T	0.666	0.93
245_T	359_T	0.666	0.93
317_L	349_L	0.664	0.93
284_V	292_L	0.663	0.93
342_F	345_V	0.663	0.93
276_I	281_H	0.662	0.93
264_D	351_Q	0.661	0.93
480_F	492_S	0.660	0.93
380_A	384_V	0.657	0.93
280_I	295_D	0.655	0.93
232_M	235_A	0.654	0.93
374_P	464_L	0.654	0.93
371_W	375_A	0.654	0.93
447_I	451_W	0.653	0.93
255_I	264_D	0.651	0.93
366_A	498_P	0.649	0.92
519_I	523_L	0.648	0.92
406_K	409_L	0.648	0.92
514_I	522_V	0.648	0.92
188_T	202_S	0.648	0.92
126_N	130_G	0.647	0.92
216_L	219_F	0.647	0.92
355_A	382_G	0.646	0.92
345_V	349_L	0.646	0.92
218_T	240_M	0.643	0.92
140_G	358_C	0.642	0.92
144_T	241_T	0.642	0.92
454_F	486_Q	0.641	0.92
218_T	243_L	0.640	0.92
364_A	371_W	0.640	0.92
206_T	391_S	0.639	0.92
143_L	491_L	0.638	0.92
146_A	151_A	0.637	0.92
478_V	495_I	0.636	0.92
473_Y	500_M	0.635	0.92
239_A	270_V	0.634	0.92
349_L	353_V	0.634	0.92
169_V	210_I	0.633	0.91
352_F	379_V	0.633	0.91
502_T	505_K	0.632	0.91
505_K	509_L	0.631	0.91
387_A	398_L	0.630	0.91
217_F	274_G	0.627	0.91
380_A	493_S	0.627	0.91
255_I	350_F	0.626	0.91
414_G	438_A	0.625	0.91
502_T	506_A	0.623	0.91
155_T	158_W	0.623	0.91
125_Q	153_P	0.622	0.91
355_A	366_A	0.622	0.91
459_A	483_A	0.621	0.91
462_F	473_Y	0.620	0.91
358_C	394_G	0.618	0.90
256_A	363_T	0.618	0.90
306_A	313_T	0.618	0.90
480_F	484_S	0.616	0.90
477_N	495_I	0.616	0.90
475_V	478_V	0.615	0.90
213_I	281_H	0.615	0.90
146_A	149_E	0.614	0.90
477_N	500_M	0.614	0.90
149_E	157_Q	0.614	0.90
143_L	492_S	0.613	0.90
234_D	250_I	0.611	0.90
381_F	456_G	0.610	0.90
412_I	527_R	0.608	0.90
350_F	361_F	0.608	0.90
240_M	244_A	0.607	0.90
308_G	402_L	0.605	0.90
486_Q	519_I	0.603	0.89
254_S	489_V	0.600	0.89
433_S	436_E	0.597	0.89
127_P	134_S	0.597	0.89
272_V	317_L	0.593	0.89
309_T	315_V	0.590	0.88
370_G	373_A	0.586	0.88
219_F	222_I	0.586	0.88
228_A	258_Y	0.586	0.88
354_S	359_T	0.585	0.88
91_L	130_G	0.584	0.88
312_L	398_L	0.583	0.88
225_L	361_F	0.583	0.88
460_F	464_L	0.581	0.88
300_W	303_G	0.581	0.88
211_W	215_L	0.580	0.87
189_L	193_E	0.580	0.87
227_I	235_A	0.579	0.87
528_G	532_T	0.579	0.87
454_F	458_A	0.579	0.87
143_L	481_E	0.579	0.87
164_E	361_F	0.579	0.87
132_F	145_M	0.578	0.87
295_D	298_T	0.577	0.87
309_T	388_A	0.577	0.87
171_V	207_V	0.577	0.87
279_P	390_G	0.572	0.87
459_A	463_M	0.571	0.87
296_L	300_W	0.570	0.87
383_M	487_G	0.570	0.87
445_A	449_F	0.569	0.86
140_G	245_T	0.568	0.86
317_L	352_F	0.567	0.86
139_T	244_A	0.563	0.86
455_L	482_V	0.563	0.86
377_L	381_F	0.563	0.86
95_W	156_L	0.562	0.86
172_I	500_M	0.562	0.86
479_L	483_A	0.561	0.86
296_L	402_L	0.560	0.86
151_A	154_H	0.558	0.85
136_S	141_T	0.558	0.85
481_E	491_L	0.556	0.85
165_W	240_M	0.555	0.85
362_Q	498_P	0.555	0.85
473_Y	477_N	0.555	0.85
279_P	283_L	0.554	0.85
158_W	237_N	0.554	0.85
445_A	450_L	0.552	0.85
481_E	508_F	0.552	0.85
499_G	503_V	0.552	0.85
455_L	479_L	0.552	0.85
144_T	149_E	0.551	0.85
373_A	376_Q	0.549	0.84
355_A	487_G	0.548	0.84
151_A	252_D	0.547	0.84
254_S	363_T	0.546	0.84
403_T	407_G	0.545	0.84
267_L	361_F	0.545	0.84
481_E	484_S	0.544	0.84
358_C	488_N	0.543	0.84
416_F	524_V	0.542	0.84
143_L	496_T	0.542	0.84
145_M	149_E	0.541	0.84
130_G	152_L	0.539	0.83
351_Q	371_W	0.538	0.83
139_T	214_F	0.537	0.83
272_V	349_L	0.537	0.83
354_S	491_L	0.536	0.83
158_W	161_S	0.535	0.83
264_D	350_F	0.534	0.83
139_T	390_G	0.534	0.83
255_I	363_T	0.534	0.83
254_S	258_Y	0.534	0.83
242_G	274_G	0.533	0.83
484_S	496_T	0.533	0.83
358_C	486_Q	0.533	0.83
308_G	311_L	0.533	0.83
392_T	397_K	0.533	0.83
179_L	525_L	0.532	0.83
353_V	484_S	0.532	0.83
301_V	305_F	0.532	0.83
256_A	259_G	0.531	0.83
408_I	449_F	0.529	0.82
91_L	125_Q	0.529	0.82
377_L	459_A	0.528	0.82
241_T	489_V	0.528	0.82
210_I	282_Y	0.527	0.82
226_W	266_A	0.527	0.82
141_T	488_N	0.527	0.82
138_F	516_R	0.526	0.82
144_T	362_Q	0.525	0.82
171_V	175_T	0.523	0.82
478_V	482_V	0.522	0.81
451_W	455_L	0.522	0.81
187_L	190_Y	0.521	0.81
268_I	352_F	0.519	0.81
374_P	463_M	0.519	0.81
124_F	153_P	0.518	0.81
362_Q	366_A	0.518	0.81
199_I	206_T	0.516	0.81
495_I	498_P	0.516	0.81
351_Q	355_A	0.515	0.81
146_A	160_R	0.515	0.81
528_G	531_S	0.513	0.80
523_L	527_R	0.513	0.80
236_I	239_A	0.513	0.80
366_A	370_G	0.513	0.80
395_G	401_L	0.513	0.80
252_D	257_T	0.513	0.80
227_I	231_P	0.512	0.80
485_A	511_N	0.512	0.80
450_L	454_F	0.511	0.80
192_S	411_R	0.511	0.80
296_L	299_R	0.510	0.80
302_F	305_F	0.508	0.80
143_L	480_F	0.508	0.80
228_A	232_M	0.507	0.80
227_I	232_M	0.507	0.80
318_Q	341_L	0.506	0.79
239_A	243_L	0.506	0.79
249_S	253_N	0.506	0.79
294_T	298_T	0.505	0.79
351_Q	364_A	0.505	0.79
137_G	163_I	0.504	0.79
481_E	500_M	0.502	0.79
147_D	151_A	0.502	0.79
139_T	516_R	0.501	0.79
148_N	153_P	0.501	0.79
206_T	211_W	0.500	0.79

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
3pjzA	2	0.8585	100	0.184	Contact Map
4j7cI	2	0.7654	100	0.337	Contact Map
3ukmA	2	0.3706	96.8	0.944	Contact Map
4twkA	2	0.4004	96.8	0.944	Contact Map
4wfeA	2	0.3855	96	0.948	Contact Map
4bw5A	2	0.3873	96	0.948	Contact Map
2a9hA	4	0.1806	84.5	0.963	Contact Map
2k1eA	3	0.1769	81.3	0.964	Contact Map
3pjsK	4	0.2402	80.8	0.964	Contact Map
3vouA	4	0.2495	79.7	0.964	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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