Q9HQ68 - HALSA - GREMLIN Contacts

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Q9HQ68 - Uncharacterized protein

UniProt:	Q9HQ68	Sequences: MPPAGGDATPGFTRAGALPGGMTHPTARNRLDEAASPYLRQHADNPVNWQPWGEPAFSAAREHDVPIFLSIGYSACHWCHVMAEESFADPEIAAVLNEQFVPVKVDREQRPDVDDLYMTVSQVTRGSGGWPLSVFLTPERKPFYITTYVPKEPTRDQPGFESLLEDVTANWRENRGDLDARAEQWLQAARGELESVPDPVDDAGTDSPLPAAAGSIADAADATHGGFGRGQKFPHAGRLRVLLRATQRDAGDGARAASAARHTLTAMADGGLHDHVGGGFHRYCTDREWTVPHFEKMLYDQAALARLYVDGYRALGDSRYADVARSTLTFVDRELGHPDGGFYATLDARSPPPDAPDGDREEGAYYVWTPNRVAAAMRDHAAAAPCDTADADVLADAACRRYGVDDTGNFEAGTTVPTVSASVGAIADAFDTAPATAEAWCDVIDARLRAARADRPRPARDEKVLAGWNGLMARAYAEAGLALDDRFAERAADAIAFARDTLWDGDRLARRSIGGDVAGVGYAADYAFLAAGALATYEATGAVAHLDFALDLADAMLEACYDASAGVLYETPASVDDVAVRSQATGTGSTPSPIGVAADTLDALAAFAPAAGYDDAAAALLSRYGSHIEESPGRHPELVLAADTRAGGRREITVAADDLPDAWRDAVGAAYLPDRLLSRRPPTEDGLDAWQSTLDQASVPPLWAGRTGGDDGTPRAYVCRRACSPPLDDAAGITEWLAEFSR	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	742 (660)
Sequences:	1680 (1262)
Seq/√Len:	49.1

BACSU - YYAL
HALSA - Q9HQ68 Q9HNX2
SULSO - Q97WL2

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
470_G	532_G	5.113	1.00
480_G	488_A	5.022	1.00
64_D	175_R	4.971	1.00
332_D	490_R	4.593	1.00
273_H	326_S	4.498	1.00
331_V	472_M	4.147	1.00
59_A	63_H	3.978	1.00
96_L	102_P	3.857	1.00
325_R	485_D	3.725	1.00
174_N	177_D	3.656	1.00
305_A	328_L	3.616	1.00
146_T	149_V	3.576	1.00
556_M	597_A	3.528	1.00
559_A	573_A	3.504	1.00
330_F	346_L	3.381	1.00
153_P	162_S	3.375	1.00
92_I	161_E	3.291	1.00
473_A	494_A	3.132	1.00
474_R	535_A	3.089	1.00
499_R	548_F	3.051	1.00
28_R	44_D	2.980	1.00
492_A	542_A	2.946	1.00
89_D	151_K	2.945	1.00
169_A	173_E	2.933	1.00
69_L	136_L	2.906	1.00
58_S	62_E	2.899	1.00
220_A	262_H	2.881	1.00
94_A	98_E	2.865	1.00
321_A	325_R	2.814	1.00
530_A	600_T	2.798	1.00
557_L	568_L	2.778	1.00
57_F	113_V	2.771	1.00
462_E	513_I	2.753	1.00
523_A	593_P	2.671	1.00
121_S	145_I	2.634	1.00
365_Y	457_R	2.613	1.00
92_I	151_K	2.604	1.00
66_P	143_F	2.583	1.00
404_V	417_P	2.566	1.00
328_L	476_Y	2.542	1.00
68_F	133_S	2.537	1.00
74_S	345_T	2.524	1.00
652_I	718_V	2.506	1.00
364_A	456_P	2.419	1.00
334_E	346_L	2.378	1.00
30_R	48_N	2.348	1.00
34_A	51_P	2.339	1.00
261_R	317_D	2.296	1.00
90_P	94_A	2.291	1.00
59_A	101_V	2.285	1.00
557_L	616_A	2.282	1.00
336_G	493_D	2.268	1.00
57_F	67_I	2.265	1.00
92_I	159_G	2.257	1.00
309_V	483_L	2.256	1.00
357_D	360_R	2.255	1.00
276_V	417_P	2.251	1.00
553_A	600_T	2.237	1.00
358_G	364_A	2.220	1.00
71_I	132_L	2.204	1.00
67_I	136_L	2.151	1.00
141_K	183_E	2.146	1.00
53_G	56_A	2.140	1.00
376_A	451_A	2.133	1.00
716_A	733_I	2.126	1.00
75_A	345_T	2.119	1.00
359_D	364_A	2.109	1.00
265_T	320_Y	2.086	1.00
378_R	381_A	2.040	1.00
538_E	603_A	2.040	1.00
262_H	266_A	2.035	1.00
246_T	257_A	2.034	1.00
495_I	545_H	2.029	1.00
360_R	364_A	2.025	1.00
328_L	479_A	2.014	1.00
32_D	44_D	2.013	1.00
50_Q	59_A	2.003	1.00
265_T	317_D	2.003	1.00
268_A	308_Y	2.000	1.00
175_R	179_D	1.998	1.00
321_A	483_L	1.995	0.99
95_V	161_E	1.987	0.99
376_A	447_R	1.945	0.99
499_R	533_A	1.941	0.99
30_R	50_Q	1.936	0.99
277_G	333_R	1.935	0.99
308_Y	323_V	1.931	0.99
358_G	456_P	1.930	0.99
220_A	259_A	1.928	0.99
304_L	308_Y	1.914	0.99
528_F	596_V	1.910	0.99
213_A	256_A	1.905	0.99
133_S	160_F	1.898	0.99
467_G	510_R	1.862	0.99
337_H	343_Y	1.861	0.99
280_F	304_L	1.843	0.99
562_D	583_Q	1.800	0.99
268_A	323_V	1.795	0.99
496_A	544_A	1.786	0.99
265_T	319_R	1.778	0.99
443_V	447_R	1.760	0.99
330_F	335_L	1.759	0.99
240_R	310_D	1.757	0.99
595_G	637_E	1.754	0.99
507_R	574_S	1.752	0.99
264_L	311_G	1.750	0.99
378_R	382_A	1.749	0.99
67_I	103_V	1.740	0.99
50_Q	53_G	1.740	0.99
466_A	529_L	1.737	0.99
727_L	736_W	1.735	0.99
280_F	308_Y	1.708	0.98
729_D	732_G	1.704	0.98
158_P	163_L	1.666	0.98
398_A	402_Y	1.662	0.98
361_E	364_A	1.654	0.98
54_E	58_S	1.649	0.98
168_T	172_R	1.647	0.98
217_A	259_A	1.645	0.98
569_Y	581_R	1.641	0.98
341_G	497_F	1.639	0.98
290_T	418_T	1.633	0.98
567_V	583_Q	1.629	0.98
302_A	475_A	1.612	0.98
89_D	92_I	1.602	0.98
239_L	260_A	1.601	0.98
495_I	533_A	1.588	0.97
309_V	475_A	1.581	0.97
495_I	536_T	1.581	0.97
95_V	165_E	1.574	0.97
476_Y	490_R	1.574	0.97
44_D	83_A	1.550	0.97
489_E	492_A	1.542	0.97
404_V	408_G	1.540	0.97
95_V	99_Q	1.530	0.97
116_L	579_A	1.529	0.97
30_R	55_P	1.528	0.97
474_R	531_A	1.524	0.97
488_A	539_A	1.522	0.97
359_D	456_P	1.515	0.97
650_R	720_R	1.512	0.97
571_T	581_R	1.509	0.96
398_A	409_N	1.501	0.96
244_R	310_D	1.498	0.96
322_D	326_S	1.497	0.96
257_A	315_L	1.486	0.96
74_S	459_A	1.480	0.96
569_Y	583_Q	1.479	0.96
290_T	416_V	1.478	0.96
397_A	401_R	1.475	0.96
367_V	414_T	1.472	0.96
664_R	668_G	1.471	0.96
212_A	639_V	1.469	0.96
605_A	608_A	1.461	0.96
306_R	478_E	1.458	0.96
594_I	624_Y	1.448	0.96
530_A	553_A	1.436	0.95
151_K	161_E	1.433	0.95
554_D	613_Y	1.418	0.95
346_L	457_R	1.404	0.95
562_D	569_Y	1.403	0.95
492_A	545_H	1.398	0.95
370_P	415_T	1.397	0.95
137_T	141_K	1.395	0.95
84_E	88_A	1.393	0.95
559_A	572_P	1.388	0.94
357_D	364_A	1.380	0.94
605_A	614_D	1.370	0.94
496_A	500_D	1.365	0.94
310_D	478_E	1.360	0.94
507_R	559_A	1.356	0.94
715_R	728_D	1.350	0.94
245_A	256_A	1.341	0.93
555_A	559_A	1.341	0.93
652_I	675_R	1.332	0.93
727_L	733_I	1.332	0.93
273_H	322_D	1.328	0.93
561_Y	616_A	1.317	0.93
135_F	160_F	1.311	0.92
248_R	643_D	1.310	0.92
331_V	335_L	1.310	0.92
610_A	613_Y	1.308	0.92
75_A	459_A	1.306	0.92
618_A	645_R	1.297	0.92
537_Y	541_G	1.294	0.92
324_A	479_A	1.291	0.92
99_Q	168_T	1.287	0.92
227_F	239_L	1.285	0.92
477_A	480_G	1.284	0.92
305_A	479_A	1.282	0.92
405_D	409_N	1.278	0.92
40_R	513_I	1.274	0.91
598_A	641_A	1.273	0.91
224_H	287_R	1.272	0.91
213_A	245_A	1.271	0.91
509_A	517_V	1.271	0.91
457_R	460_R	1.270	0.91
68_F	96_L	1.269	0.91
497_F	501_T	1.247	0.90
246_T	314_A	1.247	0.90
328_L	490_R	1.246	0.90
166_D	170_N	1.241	0.90
702_L	706_R	1.241	0.90
466_A	470_G	1.235	0.90
397_A	409_N	1.230	0.90
45_N	83_A	1.226	0.90
326_S	445_D	1.225	0.90
281_H	301_Q	1.220	0.89
333_R	449_R	1.220	0.89
368_W	451_A	1.217	0.89
32_D	43_A	1.216	0.89
398_A	411_E	1.214	0.89
553_A	568_L	1.209	0.89
69_L	133_S	1.208	0.89
305_A	475_A	1.206	0.89
550_L	613_Y	1.205	0.89
381_A	447_R	1.198	0.89
135_F	167_V	1.197	0.89
732_G	735_E	1.197	0.89
553_A	604_L	1.196	0.89
398_A	401_R	1.191	0.88
108_E	463_K	1.186	0.88
336_G	490_R	1.183	0.88
329_T	486_R	1.176	0.88
237_G	303_A	1.174	0.88
141_K	182_A	1.172	0.88
100_F	135_F	1.172	0.88
135_F	144_Y	1.169	0.87
277_G	449_R	1.168	0.87
346_L	460_R	1.165	0.87
548_F	551_D	1.157	0.87
401_R	441_C	1.157	0.87
45_N	88_A	1.156	0.87
550_L	610_A	1.152	0.87
170_N	174_N	1.151	0.87
358_G	365_Y	1.149	0.86
365_Y	449_R	1.148	0.86
449_R	453_A	1.145	0.86
342_F	494_A	1.144	0.86
325_R	487_F	1.142	0.86
309_V	482_A	1.141	0.86
32_D	48_N	1.141	0.86
332_D	486_R	1.140	0.86
243_L	260_A	1.128	0.85
572_P	575_V	1.128	0.85
727_L	732_G	1.127	0.85
532_G	536_T	1.127	0.85
328_L	487_F	1.127	0.85
28_R	32_D	1.122	0.85
124_T	185_W	1.122	0.85
161_E	165_E	1.121	0.85
37_P	40_R	1.117	0.85
291_V	416_V	1.116	0.85
346_L	366_Y	1.115	0.85
121_S	134_V	1.113	0.85
272_L	284_C	1.111	0.85
374_A	379_D	1.109	0.84
309_V	479_A	1.108	0.84
599_D	644_T	1.105	0.84
331_V	336_G	1.103	0.84
245_A	249_D	1.103	0.84
341_G	464_V	1.103	0.84
653_T	703_W	1.102	0.84
598_A	620_L	1.102	0.84
59_A	62_E	1.099	0.84
44_D	84_E	1.093	0.84
471_L	528_F	1.091	0.83
397_A	411_E	1.089	0.83
585_T	624_Y	1.086	0.83
118_M	128_G	1.085	0.83
325_R	483_L	1.081	0.83
488_A	492_A	1.080	0.83
554_D	610_A	1.080	0.83
398_A	404_V	1.079	0.83
397_A	440_W	1.076	0.83
273_H	323_V	1.076	0.83
280_F	323_V	1.073	0.82
502_L	512_S	1.067	0.82
405_D	408_G	1.066	0.82
113_V	118_M	1.065	0.82
621_L	645_R	1.064	0.82
381_A	444_I	1.064	0.82
273_H	327_T	1.060	0.82
453_A	457_R	1.060	0.82
529_L	533_A	1.057	0.81
59_A	65_V	1.057	0.81
133_S	136_L	1.051	0.81
305_A	476_Y	1.050	0.81
531_A	535_A	1.050	0.81
261_R	320_Y	1.048	0.81
586_G	634_R	1.046	0.81
70_S	73_Y	1.044	0.81
305_A	309_V	1.043	0.81
718_V	727_L	1.043	0.81
357_D	456_P	1.043	0.81
503_W	548_F	1.042	0.80
42_H	45_N	1.040	0.80
499_R	544_A	1.038	0.80
338_P	343_Y	1.038	0.80
42_H	73_Y	1.037	0.80
360_R	456_P	1.033	0.80
136_L	140_R	1.031	0.80
499_R	503_W	1.030	0.80
48_N	51_P	1.028	0.80
310_D	313_R	1.027	0.80
324_A	483_L	1.021	0.79
169_A	174_N	1.020	0.79
267_M	308_Y	1.017	0.79
488_A	540_T	1.015	0.79
34_A	518_A	1.014	0.79
667_V	733_I	1.008	0.78
496_A	545_H	1.007	0.78
48_N	59_A	1.007	0.78
663_W	667_V	1.005	0.78
269_D	319_R	1.003	0.78
231_Q	287_R	1.003	0.78
153_P	159_G	0.997	0.77
343_Y	464_V	0.992	0.77
241_V	245_A	0.991	0.77
410_F	510_R	0.990	0.77
397_A	404_V	0.990	0.77
121_S	125_R	0.989	0.77
275_H	449_R	0.988	0.77
50_Q	56_A	0.987	0.77
672_L	675_R	0.984	0.77
583_Q	594_I	0.983	0.76
446_A	450_A	0.982	0.76
58_S	61_R	0.982	0.76
397_A	402_Y	0.980	0.76
530_A	556_M	0.978	0.76
544_A	548_F	0.973	0.76
246_T	249_D	0.972	0.76
424_G	434_P	0.972	0.76
276_V	404_V	0.969	0.75
285_T	410_F	0.968	0.75
35_A	511_R	0.965	0.75
317_D	320_Y	0.963	0.75
597_A	600_T	0.963	0.75
217_A	255_R	0.963	0.75
224_H	288_E	0.962	0.75
408_G	413_G	0.960	0.75
83_A	133_S	0.959	0.75
442_D	446_A	0.959	0.75
398_A	410_F	0.959	0.75
478_E	535_A	0.959	0.75
50_Q	55_P	0.957	0.75
481_L	668_G	0.957	0.75
403_G	418_T	0.955	0.74
492_A	496_A	0.955	0.74
246_T	250_A	0.954	0.74
663_W	716_A	0.952	0.74
442_D	445_D	0.952	0.74
519_G	522_Y	0.951	0.74
405_D	411_E	0.949	0.74
119_T	123_V	0.948	0.74
510_R	522_Y	0.946	0.74
120_V	185_W	0.945	0.74
405_D	410_F	0.940	0.73
180_A	184_Q	0.939	0.73
305_A	327_T	0.937	0.73
480_G	485_D	0.937	0.73
568_L	620_L	0.934	0.73
313_R	482_A	0.933	0.73
336_G	472_M	0.932	0.73
663_W	714_P	0.931	0.72
91_E	161_E	0.930	0.72
451_A	454_D	0.930	0.72
305_A	487_F	0.928	0.72
276_V	445_D	0.925	0.72
470_G	529_L	0.923	0.72
562_D	565_A	0.919	0.71
522_Y	570_E	0.917	0.71
496_A	499_R	0.916	0.71
402_Y	441_C	0.914	0.71
154_T	157_Q	0.913	0.71
121_S	132_L	0.913	0.71
708_G	715_R	0.908	0.71
678_S	706_R	0.908	0.71
466_A	502_L	0.908	0.71
559_A	574_S	0.907	0.70
241_V	636_P	0.906	0.70
534_L	613_Y	0.904	0.70
141_K	186_L	0.901	0.70
69_L	117_Y	0.900	0.70
553_A	557_L	0.900	0.70
602_D	645_R	0.899	0.70
41_Q	45_N	0.898	0.70
35_A	516_D	0.897	0.70
720_R	724_S	0.895	0.69
381_A	440_W	0.894	0.69
272_L	327_T	0.894	0.69
497_F	512_S	0.893	0.69
118_M	123_V	0.890	0.69
404_V	409_N	0.890	0.69
372_R	414_T	0.888	0.69
470_G	474_R	0.887	0.69
553_A	556_M	0.887	0.69
38_Y	42_H	0.884	0.68
608_A	611_A	0.884	0.68
40_R	462_E	0.878	0.68
28_R	48_N	0.876	0.68
332_D	476_Y	0.876	0.68
51_P	56_A	0.875	0.68
374_A	382_A	0.875	0.68
716_A	730_A	0.870	0.67
306_R	531_A	0.868	0.67
255_R	258_S	0.868	0.67
495_I	532_G	0.867	0.67
488_A	536_T	0.865	0.67
550_L	554_D	0.864	0.67
725_P	732_G	0.864	0.67
373_V	404_V	0.863	0.67
654_V	716_A	0.863	0.67
110_R	522_Y	0.861	0.66
520_V	572_P	0.860	0.66
614_D	618_A	0.858	0.66
554_D	612_G	0.854	0.66
344_A	468_W	0.852	0.66
542_A	545_H	0.851	0.66
239_L	307_L	0.850	0.65
309_V	328_L	0.850	0.65
700_P	703_W	0.850	0.65
719_C	723_C	0.850	0.65
267_M	280_F	0.848	0.65
150_P	159_G	0.845	0.65
89_D	161_E	0.843	0.65
666_A	734_T	0.842	0.65
361_E	414_T	0.840	0.64
96_L	160_F	0.839	0.64
73_Y	463_K	0.839	0.64
124_T	145_I	0.838	0.64
260_A	307_L	0.835	0.64
213_A	217_A	0.835	0.64
134_V	145_I	0.833	0.64
336_G	494_A	0.832	0.64
42_H	70_S	0.832	0.64
524_A	570_E	0.832	0.64
42_H	463_K	0.831	0.64
99_Q	164_L	0.830	0.64
267_M	275_H	0.829	0.63
611_A	615_D	0.827	0.63
325_R	486_R	0.826	0.63
167_V	178_L	0.826	0.63
440_W	444_I	0.825	0.63
550_L	608_A	0.825	0.63
399_C	405_D	0.823	0.63
703_W	706_R	0.821	0.63
337_H	464_V	0.820	0.63
523_A	556_M	0.819	0.63
217_A	251_G	0.817	0.62
606_A	614_D	0.817	0.62
370_P	374_A	0.817	0.62
524_A	593_P	0.815	0.62
724_S	736_W	0.814	0.62
120_V	145_I	0.812	0.62
276_V	398_A	0.810	0.62
305_A	472_M	0.809	0.62
221_D	232_K	0.808	0.61
530_A	597_A	0.807	0.61
682_P	708_G	0.804	0.61
89_D	145_I	0.801	0.61
332_D	336_G	0.801	0.61
220_A	263_T	0.800	0.61
312_Y	324_A	0.799	0.61
212_A	597_A	0.795	0.60
323_V	326_S	0.795	0.60
358_G	457_R	0.795	0.60
521_G	528_F	0.794	0.60
230_G	281_H	0.794	0.60
268_A	280_F	0.794	0.60
410_F	467_G	0.793	0.60
67_I	140_R	0.791	0.60
364_A	367_V	0.790	0.60
568_L	616_A	0.790	0.60
730_A	734_T	0.789	0.60
305_A	324_A	0.787	0.59
578_V	582_S	0.786	0.59
30_R	56_A	0.784	0.59
35_A	40_R	0.784	0.59
78_W	81_V	0.781	0.59
77_H	81_V	0.781	0.59
42_H	297_M	0.778	0.59
508_L	521_G	0.778	0.59
277_G	334_E	0.776	0.58
146_T	160_F	0.776	0.58
489_E	493_D	0.774	0.58
337_H	512_S	0.770	0.58
663_W	730_A	0.770	0.58
535_A	603_A	0.769	0.58
380_H	440_W	0.768	0.58
473_A	536_T	0.768	0.58
368_W	448_L	0.766	0.57
149_V	160_F	0.764	0.57
531_A	599_D	0.763	0.57
240_R	671_Y	0.763	0.57
146_T	301_Q	0.762	0.57
284_C	288_E	0.761	0.57
42_H	108_E	0.761	0.57
335_L	456_P	0.761	0.57
169_A	732_G	0.760	0.57
371_N	375_A	0.758	0.57
718_V	733_I	0.758	0.57
45_N	73_Y	0.757	0.56
449_R	457_R	0.756	0.56
553_A	597_A	0.753	0.56
73_Y	108_E	0.752	0.56
264_L	307_L	0.751	0.56
561_Y	619_A	0.751	0.56
311_G	320_Y	0.751	0.56
532_G	552_L	0.749	0.56
53_G	57_F	0.747	0.55
503_W	508_L	0.746	0.55
57_F	102_P	0.746	0.55
596_V	600_T	0.745	0.55
342_F	490_R	0.743	0.55
462_E	515_G	0.742	0.55
337_H	341_G	0.742	0.55
208_P	625_G	0.740	0.55
181_R	185_W	0.740	0.55
290_T	405_D	0.740	0.55
466_A	533_A	0.739	0.55
346_L	365_Y	0.738	0.55
90_P	98_E	0.736	0.54
159_G	162_S	0.736	0.54
499_R	529_L	0.736	0.54
402_Y	416_V	0.734	0.54
399_C	409_N	0.733	0.54
118_M	126_G	0.729	0.54
480_G	483_L	0.729	0.54
70_S	78_W	0.729	0.54
254_A	258_S	0.724	0.53
480_G	540_T	0.724	0.53
477_A	532_G	0.724	0.53
498_A	508_L	0.723	0.53
445_D	449_R	0.723	0.53
460_R	513_I	0.723	0.53
243_L	314_A	0.722	0.53
533_A	548_F	0.721	0.53
206_D	210_P	0.720	0.53
716_A	727_L	0.719	0.53
437_A	444_I	0.719	0.53
285_T	592_S	0.718	0.53
667_V	716_A	0.718	0.53
50_Q	63_H	0.716	0.52
120_V	124_T	0.716	0.52
401_R	419_V	0.716	0.52
666_A	733_I	0.714	0.52
45_N	70_S	0.714	0.52
652_I	716_A	0.713	0.52
627_H	635_H	0.713	0.52
398_A	405_D	0.712	0.52
213_A	241_V	0.711	0.52
373_V	399_C	0.710	0.52
342_F	472_M	0.710	0.52
422_S	425_A	0.709	0.52
73_Y	77_H	0.709	0.52
370_P	382_A	0.708	0.52
45_N	299_Y	0.707	0.51
465_L	511_R	0.707	0.51
305_A	331_V	0.707	0.51
666_A	730_A	0.705	0.51
473_A	529_L	0.703	0.51
290_T	409_N	0.701	0.51
624_Y	638_L	0.701	0.51
57_F	75_A	0.700	0.51
70_S	104_K	0.699	0.51
397_A	437_A	0.699	0.51
479_A	483_L	0.698	0.50
162_S	166_D	0.698	0.50
408_G	415_T	0.696	0.50
91_E	94_A	0.695	0.50
495_I	529_L	0.693	0.50
405_D	415_T	0.692	0.50
657_D	714_P	0.692	0.50
607_F	678_S	0.692	0.50
474_R	532_G	0.692	0.50
369_T	414_T	0.690	0.50
177_D	181_R	0.689	0.50
556_M	559_A	0.688	0.49
225_G	266_A	0.686	0.49
507_R	572_P	0.685	0.49
334_E	460_R	0.685	0.49
479_A	487_F	0.684	0.49
373_V	417_P	0.683	0.49
365_Y	453_A	0.682	0.49
306_R	475_A	0.681	0.49
47_V	51_P	0.681	0.49
303_A	475_A	0.681	0.49
64_D	172_R	0.679	0.49
154_T	158_P	0.677	0.48
98_E	168_T	0.675	0.48
653_T	702_L	0.675	0.48
100_F	168_T	0.674	0.48
216_I	238_R	0.674	0.48
547_D	551_D	0.674	0.48
555_A	558_E	0.673	0.48
245_A	643_D	0.673	0.48
327_T	334_E	0.673	0.48
333_R	365_Y	0.673	0.48
31_L	39_L	0.671	0.48
113_V	136_L	0.670	0.48
135_F	149_V	0.670	0.48
599_D	637_E	0.669	0.48
70_S	81_V	0.669	0.48
398_A	444_I	0.669	0.48
45_N	74_S	0.669	0.48
303_A	307_L	0.669	0.48
37_P	462_E	0.668	0.47
134_V	149_V	0.668	0.47
74_S	496_A	0.668	0.47
170_N	178_L	0.667	0.47
480_G	539_A	0.667	0.47
42_H	74_S	0.667	0.47
261_R	311_G	0.666	0.47
712_G	717_Y	0.666	0.47
322_D	438_E	0.666	0.47
239_L	263_T	0.665	0.47
399_C	404_V	0.665	0.47
711_D	715_R	0.665	0.47
324_A	487_F	0.664	0.47
171_W	179_D	0.664	0.47
495_I	552_L	0.663	0.47
122_Q	125_R	0.662	0.47
538_E	607_F	0.662	0.47
73_Y	76_C	0.661	0.47
84_E	123_V	0.660	0.47
511_R	518_A	0.660	0.47
501_T	512_S	0.658	0.46
408_G	411_E	0.658	0.46
257_A	261_R	0.657	0.46
41_Q	88_A	0.654	0.46
301_Q	410_F	0.654	0.46
125_R	145_I	0.653	0.46
404_V	415_T	0.652	0.46
301_Q	411_E	0.652	0.46
69_L	132_L	0.650	0.46
467_G	524_A	0.650	0.46
369_T	372_R	0.649	0.46
556_M	600_T	0.649	0.46
76_C	81_V	0.648	0.45
665_D	668_G	0.648	0.45
235_H	238_R	0.648	0.45
240_R	307_L	0.647	0.45
521_G	560_C	0.646	0.45
615_D	619_A	0.646	0.45
666_A	669_A	0.645	0.45
328_L	475_A	0.644	0.45
48_N	55_P	0.644	0.45
281_H	416_V	0.643	0.45
121_S	366_Y	0.643	0.45
57_F	140_R	0.643	0.45
213_A	259_A	0.642	0.45
558_E	612_G	0.642	0.45
229_R	287_R	0.641	0.45
265_T	269_D	0.641	0.45
708_G	714_P	0.640	0.45
51_P	54_E	0.640	0.45
712_G	718_V	0.640	0.45
141_K	179_D	0.639	0.45
261_R	265_T	0.637	0.44
95_V	164_L	0.635	0.44
309_V	324_A	0.635	0.44
293_H	297_M	0.635	0.44
533_A	545_H	0.635	0.44
47_V	102_P	0.635	0.44
567_V	624_Y	0.633	0.44
77_H	80_H	0.632	0.44
543_V	547_D	0.632	0.44
84_E	284_C	0.632	0.44
702_L	705_G	0.631	0.44
170_N	177_D	0.631	0.44
152_E	161_E	0.631	0.44
37_P	45_N	0.630	0.44
50_Q	57_F	0.629	0.44
466_A	509_A	0.629	0.44
382_A	415_T	0.628	0.43
182_A	186_L	0.628	0.43
64_D	179_D	0.628	0.43
599_D	641_A	0.627	0.43
480_G	484_D	0.626	0.43
312_Y	315_L	0.625	0.43
665_D	669_A	0.625	0.43
34_A	449_R	0.624	0.43
248_R	647_G	0.624	0.43
46_P	70_S	0.624	0.43
226_G	232_K	0.624	0.43
612_G	616_A	0.623	0.43
301_Q	401_R	0.623	0.43
659_L	685_D	0.623	0.43
76_C	79_C	0.622	0.43
99_Q	102_P	0.621	0.43
29_N	39_L	0.621	0.43
118_M	122_Q	0.621	0.43
257_A	314_A	0.621	0.43
153_P	161_E	0.618	0.42
126_G	227_F	0.617	0.42
594_I	598_A	0.617	0.42
98_E	379_D	0.616	0.42
117_Y	146_T	0.616	0.42
41_Q	74_S	0.616	0.42
473_A	495_I	0.615	0.42
477_A	536_T	0.615	0.42
379_D	382_A	0.614	0.42
397_A	410_F	0.614	0.42
39_L	70_S	0.614	0.42
359_D	365_Y	0.614	0.42
39_L	42_H	0.613	0.42
121_S	146_T	0.613	0.42
278_G	329_T	0.612	0.42
81_V	104_K	0.612	0.42
268_A	278_G	0.611	0.42
275_H	418_T	0.610	0.42
374_A	378_R	0.610	0.42
73_Y	87_F	0.610	0.42
399_C	402_Y	0.610	0.42
183_E	187_Q	0.609	0.42
57_F	96_L	0.609	0.42
151_K	159_G	0.608	0.41
521_G	529_L	0.607	0.41
717_Y	726_P	0.606	0.41
602_D	641_A	0.605	0.41
144_Y	166_D	0.605	0.41
161_E	285_T	0.604	0.41
30_R	51_P	0.604	0.41
73_Y	78_W	0.603	0.41
140_R	510_R	0.603	0.41
329_T	333_R	0.602	0.41
401_R	409_N	0.601	0.41
152_E	162_S	0.600	0.41
380_H	731_A	0.599	0.41
370_P	399_C	0.598	0.40
38_Y	297_M	0.597	0.40
667_V	672_L	0.597	0.40
283_Y	293_H	0.596	0.40
176_G	179_D	0.596	0.40
492_A	540_T	0.595	0.40
642_A	646_A	0.595	0.40
62_E	101_V	0.595	0.40
503_W	551_D	0.595	0.40
373_V	376_A	0.594	0.40
153_P	158_P	0.594	0.40
102_P	266_A	0.594	0.40
648_G	720_R	0.592	0.40
332_D	342_F	0.592	0.40
231_Q	284_C	0.592	0.40
114_D	293_H	0.592	0.40
658_D	681_P	0.592	0.40
65_V	101_V	0.591	0.40
334_E	457_R	0.587	0.39
96_L	511_R	0.587	0.39
156_D	159_G	0.586	0.39
278_G	445_D	0.586	0.39
503_W	555_A	0.585	0.39
370_P	410_F	0.584	0.39
166_D	169_A	0.584	0.39
309_V	313_R	0.584	0.39
227_F	259_A	0.584	0.39
631_S	634_R	0.583	0.39
511_R	516_D	0.583	0.39
397_A	403_G	0.582	0.39
398_A	403_G	0.582	0.39
498_A	529_L	0.581	0.39
256_A	260_A	0.581	0.39
108_E	118_M	0.581	0.39
73_Y	299_Y	0.580	0.39
327_T	346_L	0.580	0.39
329_T	487_F	0.580	0.39
616_A	619_A	0.579	0.39
69_L	589_S	0.578	0.39
42_H	75_A	0.578	0.39
54_E	576_D	0.578	0.39
653_T	706_R	0.578	0.39
652_I	733_I	0.577	0.38
604_L	613_Y	0.576	0.38
64_D	138_P	0.576	0.38
373_V	655_A	0.575	0.38
69_L	105_V	0.575	0.38
110_R	116_L	0.573	0.38
281_H	519_G	0.572	0.38
261_R	315_L	0.572	0.38
70_S	74_S	0.571	0.38
104_K	299_Y	0.571	0.38
45_N	463_K	0.571	0.38
72_G	77_H	0.570	0.38
299_Y	468_W	0.570	0.38
588_G	634_R	0.570	0.38
477_A	481_L	0.569	0.38
70_S	297_M	0.568	0.38
200_V	658_D	0.568	0.38
497_F	502_L	0.568	0.38
126_G	302_A	0.567	0.37
28_R	33_E	0.566	0.37
139_E	711_D	0.565	0.37
76_C	114_D	0.565	0.37
239_L	276_V	0.565	0.37
514_G	517_V	0.565	0.37
712_G	715_R	0.565	0.37
70_S	108_E	0.564	0.37
402_Y	409_N	0.563	0.37
118_M	588_G	0.562	0.37
275_H	653_T	0.562	0.37
83_A	365_Y	0.562	0.37
64_D	496_A	0.561	0.37
127_S	157_Q	0.561	0.37
72_G	79_C	0.559	0.37
301_Q	467_G	0.559	0.37
235_H	636_P	0.559	0.37
31_L	81_V	0.557	0.37
364_A	537_Y	0.556	0.36
399_C	408_G	0.555	0.36
42_H	299_Y	0.555	0.36
470_G	533_A	0.555	0.36
209_L	643_D	0.554	0.36
673_P	679_R	0.554	0.36
38_Y	70_S	0.554	0.36
41_Q	73_Y	0.553	0.36
118_M	235_H	0.553	0.36
221_D	226_G	0.553	0.36
133_S	589_S	0.553	0.36
605_A	609_P	0.552	0.36
592_S	595_G	0.551	0.36
730_A	733_I	0.551	0.36
504_D	509_A	0.550	0.36
425_A	437_A	0.550	0.36
466_A	521_G	0.549	0.36
247_Q	673_P	0.549	0.36
305_A	329_T	0.549	0.36
345_T	628_I	0.549	0.36
281_H	366_Y	0.548	0.36
335_L	345_T	0.548	0.36
417_P	420_S	0.547	0.36
37_P	42_H	0.547	0.36
70_S	76_C	0.547	0.36
324_A	327_T	0.547	0.36
158_P	162_S	0.546	0.35
365_Y	456_P	0.546	0.35
74_S	463_K	0.546	0.35
657_D	681_P	0.546	0.35
67_I	134_V	0.545	0.35
727_L	734_T	0.545	0.35
120_V	140_R	0.545	0.35
313_R	671_Y	0.545	0.35
32_D	50_Q	0.544	0.35
706_R	717_Y	0.544	0.35
553_A	613_Y	0.543	0.35
379_D	438_E	0.542	0.35
268_A	319_R	0.542	0.35
270_G	284_C	0.542	0.35
284_C	614_D	0.542	0.35
92_I	95_V	0.541	0.35
506_D	509_A	0.541	0.35
495_I	548_F	0.541	0.35
76_C	293_H	0.541	0.35
135_F	143_F	0.541	0.35
330_F	334_E	0.540	0.35
511_R	519_G	0.540	0.35
638_L	641_A	0.540	0.35
345_T	637_E	0.540	0.35
534_L	721_R	0.540	0.35
486_R	489_E	0.539	0.35
127_S	475_A	0.539	0.35
94_A	99_Q	0.539	0.35
397_A	405_D	0.538	0.35
313_R	478_E	0.538	0.35
308_Y	311_G	0.538	0.35
313_R	673_P	0.538	0.35
82_M	104_K	0.538	0.35
477_A	535_A	0.537	0.35
56_A	101_V	0.537	0.35
114_D	282_R	0.537	0.35
368_W	458_P	0.537	0.35
30_R	53_G	0.536	0.35
624_Y	627_H	0.536	0.35
116_L	578_V	0.535	0.34
181_R	631_S	0.534	0.34
83_A	87_F	0.533	0.34
189_A	580_V	0.532	0.34
700_P	704_A	0.532	0.34
534_L	600_T	0.531	0.34
73_Y	118_M	0.531	0.34
100_F	164_L	0.531	0.34
144_Y	345_T	0.531	0.34
38_Y	45_N	0.531	0.34
680_R	683_T	0.531	0.34
299_Y	463_K	0.531	0.34
423_V	437_A	0.530	0.34
35_A	514_G	0.530	0.34
404_V	411_E	0.530	0.34
303_A	419_V	0.529	0.34
184_Q	187_Q	0.529	0.34
153_P	156_D	0.528	0.34
56_A	59_A	0.527	0.34
132_L	160_F	0.527	0.34
706_R	725_P	0.526	0.34
470_G	473_A	0.526	0.34
570_E	582_S	0.526	0.34
536_T	539_A	0.526	0.34
568_L	594_I	0.525	0.34
45_N	297_M	0.524	0.33
143_F	342_F	0.524	0.33
281_H	462_E	0.524	0.33
40_R	44_D	0.523	0.33
510_R	521_G	0.523	0.33
681_P	684_E	0.523	0.33
567_V	594_I	0.523	0.33
243_L	311_G	0.522	0.33
651_E	702_L	0.521	0.33
239_L	302_A	0.521	0.33
31_L	70_S	0.521	0.33
401_R	405_D	0.520	0.33
644_T	648_G	0.520	0.33
721_R	724_S	0.520	0.33
39_L	46_P	0.520	0.33
291_V	405_D	0.520	0.33
500_D	569_Y	0.519	0.33
329_T	332_D	0.519	0.33
722_A	725_P	0.519	0.33
285_T	376_A	0.519	0.33
717_Y	725_P	0.519	0.33
298_L	472_M	0.518	0.33
61_R	67_I	0.518	0.33
510_R	590_T	0.518	0.33
667_V	677_L	0.518	0.33
404_V	410_F	0.517	0.33
399_C	411_E	0.517	0.33
655_A	708_G	0.517	0.33
68_F	160_F	0.517	0.33
291_V	411_E	0.516	0.33
413_G	582_S	0.516	0.33
76_C	80_H	0.516	0.33
50_Q	62_E	0.516	0.33
270_G	416_V	0.515	0.33
68_F	102_P	0.515	0.33
48_N	53_G	0.514	0.33
220_A	227_F	0.514	0.33
302_A	472_M	0.514	0.33
716_A	728_D	0.514	0.33
373_V	382_A	0.514	0.33
186_L	190_R	0.513	0.32
262_H	319_R	0.513	0.32
36_S	39_L	0.513	0.32
626_S	630_E	0.513	0.32
372_R	375_A	0.512	0.32
531_A	600_T	0.512	0.32
401_R	411_E	0.512	0.32
225_G	232_K	0.512	0.32
73_Y	81_V	0.512	0.32
276_V	438_E	0.512	0.32
592_S	598_A	0.512	0.32
52_W	78_W	0.511	0.32
602_D	644_T	0.511	0.32
114_D	233_F	0.511	0.32
615_D	618_A	0.511	0.32
473_A	498_A	0.511	0.32
621_L	642_A	0.510	0.32
402_Y	405_D	0.510	0.32
602_D	621_L	0.509	0.32
299_Y	347_D	0.509	0.32
656_A	714_P	0.509	0.32
401_R	410_F	0.509	0.32
467_G	528_F	0.509	0.32
152_E	176_G	0.508	0.32
481_L	539_A	0.508	0.32
143_F	178_L	0.508	0.32
128_G	146_T	0.508	0.32
331_V	494_A	0.507	0.32
103_V	454_D	0.506	0.32
317_D	676_L	0.506	0.32
478_E	481_L	0.506	0.32
598_A	638_L	0.505	0.32
240_R	637_E	0.505	0.32
671_Y	675_R	0.504	0.32
254_A	261_R	0.504	0.32
651_E	678_S	0.504	0.32
628_I	639_V	0.503	0.32
503_W	552_L	0.503	0.32
648_G	724_S	0.503	0.32
595_G	679_R	0.503	0.32
505_G	517_V	0.502	0.31
513_I	568_L	0.502	0.31
435_A	438_E	0.502	0.31
361_E	456_P	0.502	0.31
682_P	685_D	0.502	0.31
662_A	666_A	0.502	0.31
339_D	505_G	0.502	0.31
136_L	160_F	0.502	0.31
71_I	113_V	0.501	0.31
421_A	489_E	0.501	0.31
282_R	293_H	0.501	0.31
520_V	574_S	0.500	0.31

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
3vw5A	1	0.4744	100	0.839	Contact Map
1fp3A	2	0.4798	100	0.84	Contact Map
3wkgA	1	0.4946	100	0.84	Contact Map
4c1sA	1	0.4515	100	0.842	Contact Map
2ahfA	1	0.4515	100	0.854	Contact Map
3gt5A	1	0.4946	100	0.857	Contact Map
2gz6A	2	0.4663	100	0.858	Contact Map
4v1sA	1	0.4515	100	0.864	Contact Map
5agdA	1	0.438	100	0.865	Contact Map
2zblA	5	0.5094	100	0.866	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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