GREMLIN Database
Q9HQ61 - 3-hydroxyacyl-CoA dehydrogenase
UniProt: Q9HQ61 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 659 (640)
Sequences: 898 (617)
Seq/√Len: 24.4

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
604_P607_M3.7881.00
71_L74_I3.6501.00
502_A519_A3.6171.00
137_P162_H3.5331.00
604_P609_Y3.3121.00
463_A507_Y3.1731.00
608_K611_K3.1381.00
607_M611_K3.1151.00
558_A564_T3.0981.00
622_D626_E3.0581.00
558_A565_A3.0221.00
558_A562_I2.9951.00
416_I435_L2.9811.00
606_A609_Y2.9701.00
138_A164_D2.9631.00
606_A611_K2.9221.00
593_W597_R2.9031.00
94_V100_I2.8671.00
604_P608_K2.8450.99
484_R488_Q2.8300.99
58_E61_Q2.8030.99
603_P611_K2.7730.99
275_L279_S2.7570.99
605_I611_K2.7490.99
559_K562_I2.7410.99
604_P611_K2.7270.99
599_L604_P2.7200.99
440_D492_K2.7160.99
79_E82_D2.7090.99
90_V112_A2.6940.99
603_P607_M2.6630.99
559_K565_A2.6480.99
603_P606_A2.6320.99
558_A566_D2.6320.99
405_V419_D2.6100.99
604_P610_T2.5380.99
450_A596_A2.5250.99
599_L607_M2.5090.99
599_L606_A2.5040.99
603_P609_Y2.4930.99
605_I608_K2.4900.99
560_E564_T2.4480.98
68_D74_I2.4430.98
12_L108_V2.4410.98
523_L582_V2.4320.98
562_I565_A2.4280.98
562_I566_D2.4130.98
582_V591_R2.4000.98
561_I564_T2.3880.98
142_G158_I2.3530.98
560_E565_A2.3420.98
599_L602_G2.3310.98
559_K563_F2.3150.98
326_D329_E2.2890.98
70_A74_I2.2840.98
559_K564_T2.2680.97
558_A561_I2.2490.97
589_E593_W2.2480.97
601_A604_P2.2410.97
607_M610_T2.2290.97
413_V596_A2.2160.97
599_L603_P2.1760.97
12_L76_T2.1720.97
306_D359_T2.1720.97
559_K566_D2.1450.96
68_D71_L2.1450.96
288_D292_G2.1440.96
647_A651_D2.1210.96
606_A610_T2.1060.96
599_L609_Y2.0720.96
268_D272_A2.0720.96
603_P610_T2.0330.95
378_L384_A2.0190.95
232_G236_L2.0110.95
112_A139_R1.9870.94
605_I609_Y1.9840.94
414_G448_V1.9730.94
470_M636_M1.9680.94
502_A516_A1.9620.94
379_A384_A1.9370.94
588_F593_W1.9340.93
441_V447_D1.9100.93
561_I565_A1.9080.93
563_F566_D1.9010.93
521_M595_L1.8990.93
608_K612_R1.8950.93
89_V119_A1.8950.93
9_I25_A1.8900.93
291_A294_D1.8790.92
561_I566_D1.8680.92
558_A563_F1.8580.92
605_I610_T1.8540.92
28_A583_V1.8490.92
601_A611_K1.8480.92
602_G606_A1.8210.91
560_E566_D1.8160.91
94_V104_V1.8090.91
291_A295_V1.7820.90
401_E408_S1.7820.90
374_P378_L1.7530.90
601_A606_A1.7510.89
250_D254_D1.7190.89
603_P608_K1.7040.88
173_S177_D1.6960.88
115_D139_R1.6930.88
443_G497_D1.6750.87
599_L608_K1.6560.87
606_A612_R1.6410.86
589_E595_L1.6320.86
401_E406_S1.6310.86
80_V107_E1.6270.86
335_M346_K1.6270.86
588_F591_R1.6270.86
401_E409_V1.6230.85
589_E592_A1.6210.85
523_L591_R1.6100.85
70_A73_R1.6090.85
398_G408_S1.6090.85
233_A236_L1.5930.84
557_R565_A1.5920.84
208_L211_D1.5880.84
82_D86_D1.5780.84
374_P379_A1.5710.84
560_E563_F1.5700.83
281_A285_D1.5620.83
10_A87_V1.5590.83
486_G543_W1.5560.83
46_Y49_I1.5510.83
588_F597_R1.5470.83
181_T336_L1.5460.83
129_D132_E1.5400.82
557_R564_T1.5380.82
426_T463_A1.5320.82
550_K554_G1.5300.82
113_P116_A1.5300.82
600_A604_P1.5290.82
46_Y50_E1.5280.82
44_D47_D1.5280.82
43_Q50_E1.5270.82
634_Q637_N1.5090.81
52_S56_L1.5030.81
589_E597_R1.5010.81
442_L498_E1.4990.80
109_E135_E1.4990.80
525_S585_T1.4990.80
68_D73_R1.4960.80
634_Q638_T1.4930.80
494_E548_R1.4900.80
105_Y130_L1.4870.80
52_S59_S1.4860.80
599_L611_K1.4860.80
289_D292_G1.4820.80
104_V107_E1.4810.80
601_A607_M1.4790.80
406_S409_V1.4750.79
288_D295_V1.4720.79
587_A593_W1.4650.79
439_I453_L1.4590.79
399_R437_D1.4580.79
292_G295_V1.4560.78
237_A245_S1.4530.78
358_E362_A1.4520.78
46_Y58_E1.4390.78
551_H554_G1.4330.77
56_L59_S1.4270.77
354_T358_E1.4210.77
368_G372_Y1.4200.77
46_Y61_Q1.4180.77
103_D106_T1.4110.76
367_T378_L1.4100.76
398_G401_E1.4090.76
152_M339_G1.4080.76
398_G406_S1.4070.76
588_F595_L1.4040.76
550_K553_V1.3910.75
51_W55_K1.3890.75
103_D107_E1.3890.75
557_R561_I1.3880.75
306_D363_A1.3860.75
222_T304_I1.3860.75
214_A304_I1.3750.74
321_G330_I1.3710.74
119_A141_C1.3650.74
601_A608_K1.3590.73
288_D291_A1.3550.73
557_R560_E1.3540.73
378_L386_E1.3490.73
601_A609_Y1.3480.73
306_D310_A1.3340.72
599_L610_T1.3330.72
398_G409_V1.3330.72
310_A365_E1.3310.72
552_I556_G1.3290.72
373_E378_L1.3240.71
106_T134_T1.3190.71
52_S58_E1.3180.71
109_E134_T1.3090.71
267_V271_E1.3090.71
453_L493_L1.3080.70
128_T161_A1.3060.70
44_D50_E1.3010.70
273_G279_S1.2970.70
112_A116_A1.2960.70
460_A463_A1.2880.69
493_L520_D1.2820.69
630_Q634_Q1.2790.69
601_A610_T1.2770.69
53_L58_E1.2730.68
588_F592_A1.2670.68
571_E574_A1.2630.68
14_A93_A1.2600.68
609_Y612_R1.2590.67
351_A356_L1.2550.67
612_R615_R1.2460.67
71_L75_S1.2450.67
379_A386_E1.2420.66
31_T70_A1.2310.66
274_D281_A1.2290.66
390_G393_D1.2270.65
399_R408_S1.2170.65
118_F134_T1.2160.65
239_Q339_G1.2140.65
480_V484_R1.2130.65
297_T302_A1.2130.65
76_T80_V1.2110.64
211_D307_R1.2090.64
372_Y378_L1.2090.64
490_F515_L1.2090.64
600_A610_T1.2030.64
557_R562_I1.1990.64
389_H393_D1.1970.63
516_A519_A1.1960.63
218_E300_I1.1930.63
382_A386_E1.1920.63
422_H463_A1.1850.63
50_E58_E1.1790.62
80_V104_V1.1790.62
600_A609_Y1.1760.62
388_F392_G1.1680.62
8_S86_D1.1630.61
433_A485_M1.1630.61
10_A84_V1.1620.61
246_H270_V1.1580.61
367_T372_Y1.1570.61
378_L382_A1.1570.61
42_V46_Y1.1550.61
379_A389_H1.1550.61
214_A300_I1.1540.61
155_V175_A1.1520.60
51_W58_E1.1480.60
48_Q52_S1.1430.60
52_S61_Q1.1350.59
587_A591_R1.1350.59
398_G414_G1.1330.59
374_P384_A1.1310.59
72_D82_D1.1280.59
604_P612_R1.1270.59
16_N244_V1.1260.59
128_T160_G1.1260.59
605_I612_R1.1220.58
560_E576_Y1.1210.58
378_L388_F1.1210.58
403_D430_E1.1200.58
50_E55_K1.1200.58
390_G394_E1.1200.58
404_A408_S1.1170.58
378_L385_G1.1150.58
120_T127_I1.1140.58
46_Y52_S1.1120.58
70_A75_S1.1030.57
200_P311_V1.1010.57
607_M612_R1.1000.57
401_E404_A1.0990.57
60_D63_T1.0990.57
586_E589_E1.0960.57
524_A570_P1.0950.56
49_I61_Q1.0900.56
367_T379_A1.0870.56
39_A42_V1.0870.56
239_Q277_R1.0840.56
470_M542_G1.0810.55
289_D293_A1.0810.55
119_A143_M1.0780.55
209_V234_F1.0730.55
108_V111_H1.0720.55
439_I489_T1.0700.55
399_R409_V1.0680.55
600_A611_K1.0670.54
46_Y51_W1.0670.54
61_Q65_A1.0660.54
50_E54_G1.0650.54
56_L61_Q1.0560.54
59_S62_L1.0530.53
425_N455_G1.0510.53
386_E392_G1.0500.53
41_L47_D1.0490.53
601_A605_I1.0480.53
567_R573_L1.0430.53
397_D400_R1.0430.53
411_G593_W1.0400.53
24_V27_M1.0390.52
379_A385_G1.0380.52
600_A603_P1.0380.52
602_G607_M1.0370.52
414_G442_L1.0360.52
385_G393_D1.0330.52
524_A579_I1.0320.52
81_S85_D1.0310.52
552_I555_E1.0280.52
102_T133_V1.0280.52
378_L389_H1.0250.51
374_P377_T1.0240.51
384_A389_H1.0240.51
384_A388_F1.0160.51
81_S111_H1.0090.50
494_E547_Q1.0050.50
58_E63_T1.0020.50
287_G290_A1.0020.50
368_G378_L1.0010.50
386_E389_H0.9980.50
639_Q643_E0.9970.49
367_T374_P0.9970.49
90_V139_R0.9970.49
310_A359_T0.9910.49
227_M305_A0.9900.49
418_L455_G0.9860.49
599_L605_I0.9850.49
222_T305_A0.9820.48
176_A587_A0.9820.48
269_H274_D0.9790.48
258_T261_E0.9790.48
43_Q46_Y0.9780.48
288_D294_D0.9770.48
516_A522_R0.9740.48
540_L631_S0.9740.48
289_D295_V0.9710.48
141_C171_I0.9700.48
55_K58_E0.9680.47
592_A597_R0.9670.47
90_V108_V0.9650.47
194_V324_V0.9630.47
89_V143_M0.9620.47
602_G609_Y0.9590.47
388_F394_E0.9590.47
76_T108_V0.9560.47
422_H431_L0.9560.47
109_E112_A0.9490.46
404_A409_V0.9480.46
58_E66_A0.9470.46
49_I58_E0.9470.46
46_Y59_S0.9430.46
373_E379_A0.9400.45
58_E65_A0.9400.45
504_I528_S0.9390.45
53_L73_R0.9380.45
48_Q51_W0.9360.45
379_A382_A0.9350.45
287_G294_D0.9350.45
45_G48_Q0.9340.45
373_E384_A0.9340.45
388_F391_R0.9260.44
488_Q622_D0.9250.44
402_F408_S0.9230.44
587_A597_R0.9230.44
378_L381_M0.9210.44
50_E61_Q0.9210.44
483_S633_G0.9200.44
246_H262_P0.9190.44
174_L524_A0.9190.44
398_G404_A0.9190.44
413_V450_A0.9180.44
50_E53_L0.9180.44
49_I53_L0.9150.44
50_E59_S0.9150.44
12_L111_H0.9090.43
359_T363_A0.9080.43
64_E575_D0.9080.43
332_E335_M0.9060.43
432_L489_T0.9060.43
388_F393_D0.9060.43
518_C547_Q0.9010.43
491_G547_Q0.9000.43
600_A607_M0.8970.42
470_M539_L0.8950.42
57_A61_Q0.8930.42
645_V649_S0.8910.42
517_T567_R0.8910.42
223_T233_A0.8900.42
52_S55_K0.8900.42
42_V61_Q0.8900.42
504_I516_A0.8890.42
505_D588_F0.8860.42
153_E181_T0.8840.41
265_V269_H0.8830.41
401_E407_V0.8820.41
45_G49_I0.8820.41
168_L184_R0.8820.41
378_L383_A0.8810.41
591_R595_L0.8790.41
9_I30_Y0.8780.41
172_E184_R0.8780.41
310_A363_A0.8760.41
197_I316_V0.8750.41
372_Y377_T0.8720.41
90_V111_H0.8710.41
600_A606_A0.8710.41
590_E594_E0.8700.40
243_D278_K0.8690.40
342_E350_A0.8680.40
591_R597_R0.8650.40
310_A356_L0.8640.40
418_L425_N0.8640.40
368_G388_F0.8620.40
42_V45_G0.8560.40
586_E593_W0.8540.39
462_S513_M0.8520.39
201_L236_L0.8510.39
127_I131_S0.8500.39
236_L245_S0.8490.39
378_L387_S0.8480.39
187_K231_M0.8450.39
410_D593_W0.8410.39
633_G637_N0.8410.39
191_G251_Y0.8400.38
58_E62_L0.8390.38
116_A139_R0.8380.38
49_I59_S0.8380.38
560_E578_F0.8370.38
8_S33_R0.8360.38
77_H107_E0.8340.38
380_E387_S0.8330.38
43_Q49_I0.8330.38
416_I451_V0.8310.38
542_G546_T0.8300.38
391_R394_E0.8270.38
530_L579_I0.8260.37
82_D113_P0.8260.37
262_P266_L0.8250.37
61_Q66_A0.8240.37
573_L579_I0.8240.37
401_E405_V0.8220.37
516_A530_L0.8220.37
385_G389_H0.8220.37
49_I52_S0.8220.37
288_D293_A0.8190.37
476_P637_N0.8180.37
208_L311_V0.8170.37
601_A612_R0.8170.37
602_G605_I0.8160.37
112_A115_D0.8160.37
226_D305_A0.8150.37
298_D303_D0.8120.37
436_S492_K0.8120.37
193_V426_T0.8090.36
591_R594_E0.8080.36
518_C548_R0.8040.36
382_A385_G0.8040.36
62_L71_L0.8040.36
130_L244_V0.8040.36
475_D478_E0.8040.36
55_K59_S0.8030.36
68_D75_S0.7990.36
400_R408_S0.7980.36
466_D469_S0.7980.36
414_G441_V0.7970.36
189_S323_G0.7960.35
58_E67_A0.7940.35
270_V280_G0.7930.35
98_M129_D0.7930.35
194_V312_M0.7930.35
268_D271_E0.7920.35
357_H360_L0.7920.35
289_D294_D0.7910.35
371_R379_A0.7890.35
384_A387_S0.7880.35
152_M239_Q0.7870.35
557_R566_D0.7830.35
376_D379_A0.7820.35
640_D643_E0.7820.35
368_G373_E0.7790.34
229_L236_L0.7780.34
398_G448_V0.7780.34
33_R82_D0.7760.34
56_L60_D0.7750.34
51_W57_A0.7730.34
500_V520_D0.7720.34
409_V415_H0.7700.34
206_A237_A0.7700.34
30_Y70_A0.7690.34
42_V52_S0.7680.34
439_I493_L0.7670.34
491_G548_R0.7660.34
384_A393_D0.7630.33
42_V50_E0.7630.33
53_L57_A0.7630.33
593_W596_A0.7620.33
355_Y359_T0.7600.33
428_S466_D0.7560.33
183_V193_V0.7550.33
16_N24_V0.7540.33
20_G93_A0.7530.33
73_R76_T0.7530.33
11_V15_G0.7520.33
51_W61_Q0.7520.33
51_W59_S0.7480.32
61_Q67_A0.7470.32
35_R74_I0.7450.32
368_G374_P0.7440.32
379_A387_S0.7430.32
202_L237_A0.7420.32
42_V47_D0.7420.32
436_S489_T0.7400.32
42_V48_Q0.7390.32
425_N457_G0.7380.32
381_M384_A0.7380.32
626_E637_N0.7380.32
81_S110_A0.7360.32
250_D267_V0.7350.32
109_E118_F0.7340.32
42_V105_Y0.7340.32
166_A170_C0.7320.31
42_V51_W0.7320.31
47_D51_W0.7320.31
46_Y53_L0.7310.31
374_P382_A0.7310.31
643_E647_A0.7290.31
378_L393_D0.7250.31
49_I56_L0.7240.31
529_E536_D0.7240.31
367_T371_R0.7240.31
374_P385_G0.7220.31
201_L229_L0.7220.31
95_P100_I0.7210.31
386_E391_R0.7210.31
108_V118_F0.7210.31
225_Y244_V0.7200.31
119_A171_I0.7190.31
38_S42_V0.7190.31
43_Q51_W0.7190.31
486_G490_F0.7180.31
379_A383_A0.7170.31
375_A378_L0.7170.31
9_I32_V0.7170.31
26_A540_L0.7160.30
426_T431_L0.7160.30
454_T505_D0.7140.30
374_P386_E0.7140.30
130_L140_F0.7140.30
181_T197_I0.7110.30
120_T130_L0.7090.30
157_V172_E0.7090.30
265_V283_F0.7090.30
212_D307_R0.7090.30
81_S114_A0.7080.30
7_H118_F0.7080.30
215_T299_A0.7080.30
377_T381_M0.7080.30
600_A608_K0.7070.30
8_S31_T0.7070.30
68_D72_D0.7050.30
355_Y358_E0.7050.30
405_V408_S0.7040.30
397_D409_V0.7030.30
463_A473_N0.7020.30
194_V517_T0.7020.30
392_G395_D0.7010.30
428_S486_G0.7000.29
396_A406_S0.7000.29
524_A573_L0.6990.29
427_I431_L0.6980.29
396_A408_S0.6980.29
386_E390_G0.6980.29
387_S392_G0.6970.29
84_V108_V0.6960.29
402_F409_V0.6950.29
358_E361_V0.6940.29
383_A388_F0.6930.29
299_A302_A0.6920.29
59_S63_T0.6910.29
329_E523_L0.6900.29
245_S338_A0.6860.29
108_V112_A0.6850.29
112_A118_F0.6830.28
103_D161_A0.6830.28
586_E597_R0.6820.28
398_G405_V0.6800.28
212_D304_I0.6790.28
39_A43_Q0.6790.28
106_T110_A0.6790.28
55_K61_Q0.6780.28
46_Y56_L0.6780.28
388_F395_D0.6760.28
45_G61_Q0.6740.28
382_A393_D0.6740.28
164_D218_E0.6720.28
626_E630_Q0.6720.28
191_G336_L0.6720.28
56_L79_E0.6690.28
6_I9_I0.6680.28
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48_Q61_Q0.6650.27
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271_E519_A0.6530.27
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376_D381_M0.6520.27
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574_A579_I0.6510.27
238_D276_G0.6500.27
142_G223_T0.6490.27
304_I311_V0.6480.26
107_E137_P0.6480.26
504_I508_C0.6470.26
269_H273_G0.6460.26
602_G608_K0.6460.26
429_G542_G0.6450.26
125_L552_I0.6440.26
389_H394_E0.6440.26
438_A451_V0.6430.26
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54_G59_S0.6430.26
602_G610_T0.6420.26
314_N365_E0.6420.26
376_D385_G0.6410.26
399_R406_S0.6380.26
44_D48_Q0.6370.26
87_V116_A0.6370.26
377_T380_E0.6360.26
513_M530_L0.6340.26
582_V585_T0.6340.26
158_I223_T0.6340.26
225_Y280_G0.6330.26
215_T218_E0.6330.26
38_S77_H0.6330.26
595_L598_D0.6320.26
46_Y54_G0.6320.26
397_D408_S0.6320.26
368_G389_H0.6320.26
454_T589_E0.6320.26
379_A393_D0.6300.25
546_T624_G0.6300.25
235_E277_R0.6290.25
378_L392_G0.6290.25
313_A351_A0.6290.25
43_Q52_S0.6280.25
42_V59_S0.6280.25
340_Y486_G0.6280.25
107_E267_V0.6280.25
357_H361_V0.6270.25
402_F405_V0.6260.25
586_E592_A0.6250.25
616_A619_D0.6250.25
602_G611_K0.6250.25
380_E383_A0.6250.25
49_I55_K0.6250.25
50_E56_L0.6230.25
45_G55_K0.6230.25
435_L440_D0.6220.25
368_G380_E0.6220.25
110_A116_A0.6210.25
110_A114_A0.6210.25
106_T133_V0.6200.25
431_L494_E0.6200.25
379_A391_R0.6200.25
460_A507_Y0.6180.25
42_V58_E0.6180.25
399_R402_F0.6170.25
373_E386_E0.6170.25
219_V427_I0.6170.25
565_A572_T0.6170.25
643_E646_S0.6160.25
49_I57_A0.6160.25
384_A391_R0.6160.25
97_K250_D0.6160.25
80_V103_D0.6150.25
381_M387_S0.6150.25
373_E377_T0.6140.25
142_G159_S0.6140.25
127_I142_G0.6140.25
626_E634_Q0.6130.25
400_R419_D0.6120.25
389_H395_D0.6110.24
600_A614_M0.6110.24
60_D66_A0.6100.24
385_G388_F0.6090.24
208_L308_L0.6080.24
520_D559_K0.6080.24
217_A284_Y0.6070.24
456_A505_D0.6050.24
7_H362_A0.6040.24
396_A409_V0.6040.24
371_R377_T0.6030.24
399_R404_A0.6030.24
42_V49_I0.6030.24
376_D388_F0.6020.24
175_A182_P0.6020.24
125_L302_A0.6020.24
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418_L431_L0.6000.24
435_L439_I0.6000.24
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312_M479_A0.5850.23
202_L457_G0.5850.23
620_D636_M0.5840.23
390_G395_D0.5840.23
600_A605_I0.5840.23
204_E311_V0.5830.23
98_M125_L0.5830.23
232_G235_E0.5820.23
310_A314_N0.5820.23
206_A249_L0.5810.23
235_E280_G0.5800.23
208_L307_R0.5780.23
592_A595_L0.5780.23
48_Q58_E0.5770.23
429_G433_A0.5770.23
256_L498_E0.5760.23
252_M256_L0.5760.23
250_D253_Q0.5750.23
383_A393_D0.5740.23
124_S251_Y0.5740.23
219_V233_A0.5730.23
212_D303_D0.5730.23
368_G379_A0.5720.22
54_G58_E0.5710.22
455_G505_D0.5710.22
467_V649_S0.5710.22
124_S191_G0.5710.22
195_N337_G0.5710.22
17_M21_I0.5700.22
25_A197_I0.5700.22
119_A155_V0.5690.22
118_F133_V0.5690.22
255_V576_Y0.5690.22
373_E376_D0.5680.22
197_I334_V0.5680.22
162_H519_A0.5680.22
372_Y384_A0.5670.22
620_D623_A0.5670.22
377_T384_A0.5670.22
426_T521_M0.5670.22
236_L263_C0.5670.22
94_V265_V0.5670.22
414_G438_A0.5660.22
373_E381_M0.5650.22
90_V135_E0.5650.22
120_T125_L0.5650.22
437_D441_V0.5640.22
589_E596_A0.5640.22
76_T94_V0.5640.22
361_V554_G0.5640.22
605_I614_M0.5640.22
215_T517_T0.5630.22
204_E208_L0.5620.22
444_D447_D0.5620.22
356_L359_T0.5620.22
400_R404_A0.5620.22
604_P615_R0.5610.22
508_C519_A0.5610.22
457_G505_D0.5610.22
12_L20_G0.5600.22
52_S60_D0.5590.22
376_D389_H0.5590.22
266_L539_L0.5590.22
10_A33_R0.5590.22
107_E110_A0.5580.22
463_A614_M0.5580.22
348_A356_L0.5580.22
459_K463_A0.5580.22
630_Q638_T0.5570.22
587_A595_L0.5570.22
603_P613_A0.5570.22
193_V323_G0.5570.22
382_A389_H0.5570.22
84_V111_H0.5570.22
10_A108_V0.5560.22
356_L414_G0.5550.22
588_F596_A0.5550.22
470_M475_D0.5550.22
376_D384_A0.5540.22
274_D279_S0.5540.22
626_E639_Q0.5540.22
374_P380_E0.5540.22
552_I580_N0.5530.22
184_R329_E0.5530.22
199_V237_A0.5520.21
163_T167_V0.5520.21
385_G394_E0.5520.21
131_S555_E0.5520.21
202_L245_S0.5520.21
39_A58_E0.5520.21
236_L338_A0.5500.21
356_L360_L0.5500.21
436_S485_M0.5490.21
168_L242_I0.5490.21
614_M617_G0.5490.21
45_G52_S0.5490.21
18_G21_I0.5490.21
557_R563_F0.5480.21
65_A440_D0.5480.21
406_S417_E0.5460.21
85_D551_H0.5460.21
25_A91_I0.5440.21
466_D470_M0.5440.21
577_G598_D0.5440.21
367_T389_H0.5440.21
373_E388_F0.5440.21
209_V219_V0.5430.21
41_L49_I0.5430.21
284_Y469_S0.5430.21
99_E481_E0.5430.21
84_V90_V0.5430.21
177_D587_A0.5430.21
20_G109_E0.5430.21
54_G426_T0.5430.21
152_M160_G0.5420.21
39_A46_Y0.5400.21
456_A525_S0.5400.21
470_M479_A0.5400.21
85_D298_D0.5390.21
92_E101_K0.5390.21
453_L540_L0.5390.21
439_I443_G0.5380.21
38_S78_V0.5380.21
23_E150_V0.5380.21
91_I158_I0.5370.21
537_L648_F0.5370.21
131_S556_G0.5340.21
60_D67_A0.5340.21
484_R626_E0.5340.21
469_S580_N0.5340.21
20_G598_D0.5340.21
432_L486_G0.5330.21
602_G614_M0.5320.21
371_R374_P0.5320.21
286_Y295_V0.5310.20
490_F505_D0.5310.20
505_D508_C0.5310.20
514_E534_E0.5310.20
508_C513_M0.5290.20
59_S71_L0.5290.20
376_D393_D0.5290.20
43_Q58_E0.5280.20
516_A528_S0.5280.20
12_L310_A0.5280.20
479_A636_M0.5270.20
474_A479_A0.5270.20
67_A70_A0.5270.20
58_E64_E0.5260.20
59_S66_A0.5260.20
132_E528_S0.5250.20
38_S75_S0.5240.20
187_K323_G0.5220.20
385_G391_R0.5220.20
522_R579_I0.5210.20
230_P236_L0.5210.20
41_L284_Y0.5210.20
189_S240_V0.5200.20
376_D392_G0.5200.20
152_M305_A0.5200.20
223_T229_L0.5200.20
41_L54_G0.5170.20
47_D261_E0.5170.20
412_N449_R0.5170.20
97_K357_H0.5160.20
8_S107_E0.5160.20
383_A386_E0.5150.20
377_T386_E0.5150.20
94_V436_S0.5150.20
603_P615_R0.5140.20
460_A623_A0.5140.20
305_A308_L0.5140.20
400_R406_S0.5140.20
50_E60_D0.5140.20
376_D380_E0.5130.20
431_L434_D0.5130.20
201_L486_G0.5130.20
286_Y291_A0.5120.20
386_E394_E0.5120.20
396_A401_E0.5120.20
48_Q62_L0.5110.20
491_G622_D0.5110.20
191_G236_L0.5110.20
62_L65_A0.5110.20
391_R395_D0.5100.20
73_R542_G0.5100.20
147_N230_P0.5100.20
403_D407_V0.5100.20
324_V330_I0.5100.20
113_P496_A0.5090.19
8_S170_C0.5090.19
268_D575_D0.5080.19
405_V434_D0.5080.19
387_S390_G0.5070.19
369_Q373_E0.5070.19
7_H358_E0.5070.19
636_M646_S0.5060.19
44_D55_K0.5060.19
368_G371_R0.5050.19
131_S142_G0.5050.19
75_S78_V0.5050.19
209_V232_G0.5050.19
457_G506_G0.5050.19
380_E384_A0.5050.19
604_P613_A0.5050.19
269_H334_V0.5040.19
603_P612_R0.5040.19
543_W632_F0.5040.19
136_R312_M0.5030.19
205_A427_I0.5020.19
169_E184_R0.5010.19
97_K103_D0.5010.19
254_D366_A0.5000.19
462_S641_L0.5000.19
238_D282_G0.5000.19
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
1wdkA 2 0.5812 100 0.634 Contact Map
2wtbA 1 0.5508 100 0.639 Contact Map
3k6jA 1 0.5615 100 0.646 Contact Map
3zwcA 1 0.5979 100 0.646 Contact Map
1zcjA 1 0.5964 100 0.652 Contact Map
4b3hA 1 0.569 100 0.659 Contact Map
3mogA 3 0.5827 100 0.673 Contact Map
4j0eA 2 0.4325 100 0.727 Contact Map
1f0yA 2 0.431 100 0.737 Contact Map
4r1nA 2 0.4264 100 0.742 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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