GREMLIN Database
Q9HQ35 - Uncharacterized protein
UniProt: Q9HQ35 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 90 (72)
Sequences: 1091 (642)
Seq/√Len: 75.7

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
48_P83_R3.5021.00
45_E59_R3.0841.00
24_A76_E2.7921.00
40_T63_T2.4641.00
38_S69_G2.2441.00
65_E71_P2.2411.00
29_N70_E2.1811.00
31_T37_L2.0271.00
42_E63_T1.9551.00
61_R76_E1.9511.00
31_T72_K1.8011.00
54_D83_R1.7611.00
63_T71_P1.7421.00
66_N70_E1.6421.00
52_K55_R1.4490.99
16_S79_V1.4310.99
60_T79_V1.4030.99
35_E67_E1.3880.99
62_V75_M1.3880.99
26_R74_T1.3880.99
39_V64_T1.3720.98
61_R74_T1.3680.98
42_E61_R1.3670.98
64_T73_L1.3450.98
16_S81_Y1.2400.97
24_A74_T1.1970.96
67_E72_K1.1880.96
35_E66_N1.1820.96
17_Y55_R1.1700.96
44_L61_R1.1310.95
40_T65_E1.1310.95
49_S52_K1.0510.93
41_V60_T1.0400.92
14_T81_Y1.0240.92
19_A77_P1.0240.92
28_P71_P0.9980.91
62_V79_V0.9870.90
43_V58_V0.9760.90
59_R78_I0.9760.90
64_T75_M0.9700.89
35_E72_K0.9650.89
39_V62_V0.9540.88
55_R80_L0.9270.87
23_D59_R0.9270.87
37_L64_T0.9260.87
20_V77_P0.9250.87
41_V62_V0.9220.87
19_A22_V0.9000.85
27_W33_P0.8730.84
22_V27_W0.8370.81
63_T74_T0.8320.80
59_R76_E0.8100.79
57_T78_I0.8030.78
23_D78_I0.7980.78
47_T78_I0.7930.77
65_E69_G0.7760.76
44_L76_E0.7620.74
57_T80_L0.7320.71
16_S60_T0.7250.71
27_W73_L0.7180.70
18_G81_Y0.7110.69
37_L72_K0.7010.68
60_T77_P0.6970.68
71_P74_T0.6850.66
16_S33_P0.6800.66
47_T53_P0.6800.66
16_S22_V0.6720.65
36_T72_K0.6640.64
49_S57_T0.6560.63
22_V75_M0.6540.63
43_V60_T0.6510.62
49_S78_I0.6460.62
47_T50_E0.6450.62
38_S65_E0.6440.62
29_N66_N0.6440.62
15_A79_V0.6370.61
25_L75_M0.6310.60
20_V57_T0.6240.59
35_E38_S0.6220.59
55_R82_A0.6170.58
36_T41_V0.6160.58
17_Y82_A0.6140.58
65_E84_H0.6110.57
20_V80_L0.5940.55
22_V55_R0.5910.55
47_T51_S0.5890.55
49_S53_P0.5730.53
37_L65_E0.5690.52
54_D85_T0.5650.52
58_V77_P0.5640.52
45_E76_E0.5580.51
29_N71_P0.5540.50
14_T47_T0.5520.50
58_V68_A0.5500.50
52_K57_T0.5420.49
33_P37_L0.5370.48
47_T57_T0.5370.48
26_R46_K0.5360.48
19_A27_W0.5310.47
21_G31_T0.5190.46
39_V83_R0.5160.46
15_A82_A0.5130.45
58_V83_R0.5110.45
23_D76_E0.5070.44
55_R83_R0.5050.44
15_A18_G0.5050.44
28_P74_T0.5010.44
62_V81_Y0.5000.44
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
2bi0A 3 0.8444 99.5 0.544 Contact Map
4e3eA 3 0.9111 99.5 0.568 Contact Map
4ffuA 6 0.9667 99.4 0.587 Contact Map
1q6wA 6 0.9222 99.4 0.588 Contact Map
3exzA 2 0.9333 99.3 0.593 Contact Map
4w78A 2 0.9556 99 0.653 Contact Map
4v12A 2 0.9556 99 0.656 Contact Map
3ir3A 2 0.8556 98.8 0.674 Contact Map
4rv2A 2 0.8111 98.8 0.679 Contact Map
2c2iA 2 0.8889 98.7 0.684 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.0049 seconds.