HTR9 - HALSA - GREMLIN Contacts

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HTR9 - Halobacterial transducer protein 9

UniProt:	Q9HQ00	Sequences: MSKNKHELGSPFTVPLLLNTLDVPAFAVDADGAVVAWDDQIAALLETAPEDAIGVTDIGERLNDDGSRALANKVADTPIDAHHEYDGVGLADESYALLTGDYVYEDTTVAGNTDLWFIATPVYHTGEFRGVIEIVQDRSSSARYQSELQALFGELVDTLDAYDAGRFDATVDIAAEDTLLDDEYIQIGRNLTEFGDTLAAHITEVHNDVERLEAASQAVSESSAEIDELSTAQSTNVSTVATEVETLSATVQEIASTADEVVDTSATAERLADDGSAAASDAADMMADVATAADSVTSDVEALQNRIEDIDEVVDVITGIAEQTNMLALNASIEAARAGEEGEGFAVVAEEVKALAEDAQSNAGHIESLVSEIQRDTADTVTDLVTTTDRIEDAVAQVEDAMASFEEIVTAVEATAEGIEQVSDATNEQAASAEEIAAMVDETADLADDITTAVADIVSQTEAQSAMLHDLDESVSELHDQ	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	481 (413)
Sequences:	19669 (15626)
Seq/√Len:	768.9

ECOLI - MCP3 AER MCP4 MCP2 MCP1
BACSU - YVAQ TLPA MCPB TLPB MCPA MCPC YOAH TLPC HEMAT YFMS
HALSA - HTR9 Q9HQX8 Q9HPA2 HTR4 HTR7 HMAT HTR2 Q9HRA1 Q9HP10 Q9HRN6 COST Q9HS86 Q9HR88 Q9HQT5 Q9HPQ5 HTR1 Q9HPW6

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
161_A	166_R	3.001	1.00
175_A	185_I	2.823	1.00
161_A	169_A	2.545	1.00
170_T	199_A	2.451	1.00
78_P	81_A	2.390	1.00
192_T	195_G	2.370	1.00
306_R	372_E	2.164	1.00
145_Q	149_Q	2.150	1.00
271_L	407_E	2.147	1.00
156_V	186_Q	2.145	1.00
160_D	186_Q	2.138	1.00
124_H	128_F	2.105	1.00
146_S	150_A	2.078	1.00
155_L	188_G	2.066	1.00
306_R	376_D	2.057	1.00
288_D	390_R	2.056	1.00
156_V	190_N	2.050	1.00
182_D	185_I	2.050	1.00
305_N	308_E	2.026	1.00
302_A	376_D	2.012	1.00
277_A	281_D	1.963	1.00
160_D	164_A	1.931	1.00
160_D	193_E	1.930	1.00
315_D	319_G	1.926	1.00
396_A	400_D	1.879	1.00
309_D	312_E	1.872	1.00
121_P	125_T	1.864	1.00
170_T	196_D	1.856	1.00
392_E	396_A	1.812	1.00
192_T	196_D	1.795	1.00
399_E	403_A	1.793	1.00
162_Y	195_G	1.790	1.00
292_A	386_T	1.784	1.00
253_E	256_S	1.777	1.00
289_V	394_A	1.775	1.00
283_A	402_M	1.775	1.00
162_Y	194_F	1.762	1.00
159_L	194_F	1.742	1.00
304_Q	381_V	1.740	1.00
284_D	288_D	1.726	1.00
170_T	192_T	1.725	1.00
274_D	277_A	1.710	1.00
435_E	438_A	1.689	1.00
159_L	191_L	1.686	1.00
72_N	76_D	1.684	1.00
281_D	397_Q	1.676	1.00
312_E	315_D	1.669	1.00
270_R	274_D	1.663	1.00
393_D	396_A	1.646	1.00
229_L	446_L	1.643	1.00
199_A	203_T	1.640	1.00
120_T	124_H	1.626	1.00
367_E	371_S	1.607	1.00
200_A	204_E	1.597	1.00
160_D	190_N	1.581	1.00
389_D	393_D	1.578	1.00
470_D	473_E	1.576	1.00
69_A	72_N	1.575	1.00
414_A	417_E	1.571	1.00
299_D	379_D	1.566	1.00
300_V	380_T	1.550	1.00
127_E	131_V	1.536	1.00
442_E	445_D	1.529	1.00
267_T	270_R	1.528	1.00
462_E	466_A	1.528	1.00
403_A	407_E	1.520	1.00
311_D	374_Q	1.514	1.00
186_Q	189_R	1.511	1.00
159_L	190_N	1.500	1.00
128_F	132_I	1.498	1.00
123_Y	127_E	1.497	1.00
359_A	363_A	1.495	1.00
463_A	466_A	1.490	1.00
236_N	442_E	1.486	1.00
281_D	284_D	1.475	1.00
413_E	417_E	1.475	1.00
299_D	380_T	1.475	1.00
170_T	195_G	1.474	1.00
119_A	123_Y	1.465	1.00
280_S	284_D	1.464	1.00
318_T	367_E	1.462	1.00
112_N	116_W	1.453	1.00
263_D	266_A	1.451	1.00
266_A	270_R	1.448	1.00
153_G	156_V	1.444	1.00
260_E	263_D	1.440	1.00
354_A	357_E	1.431	1.00
284_D	287_A	1.430	1.00
141_S	145_Q	1.423	1.00
305_N	309_D	1.419	1.00
400_D	403_A	1.415	1.00
301_E	305_N	1.414	1.00
287_A	399_E	1.411	1.00
68_R	72_N	1.409	1.00
306_R	309_D	1.409	1.00
206_H	210_E	1.407	1.00
466_A	470_D	1.405	1.00
221_E	225_E	1.399	1.00
263_D	267_T	1.398	1.00
155_L	187_I	1.398	1.00
309_D	365_H	1.396	1.00
427_N	431_A	1.395	1.00
292_A	390_R	1.388	1.00
357_E	361_S	1.387	1.00
350_E	353_K	1.381	1.00
219_V	223_S	1.377	1.00
278_A	400_D	1.364	1.00
378_A	382_T	1.364	1.00
113_T	117_F	1.361	1.00
166_R	169_A	1.359	1.00
361_S	365_H	1.359	1.00
261_V	419_I	1.358	1.00
469_H	473_E	1.356	1.00
281_D	400_D	1.355	1.00
120_T	123_Y	1.351	1.00
403_A	406_E	1.351	1.00
273_D	277_A	1.346	1.00
272_A	409_V	1.345	1.00
385_V	389_D	1.340	1.00
273_D	413_E	1.337	1.00
235_T	238_S	1.333	1.00
277_A	280_S	1.332	1.00
407_E	410_T	1.330	1.00
364_G	368_S	1.328	1.00
224_A	228_E	1.327	1.00
389_D	392_E	1.321	1.00
196_D	200_A	1.320	1.00
204_E	470_D	1.318	1.00
102_Y	106_D	1.315	1.00
97_L	101_D	1.315	1.00
88_V	92_D	1.315	1.00
452_T	455_A	1.314	1.00
295_S	298_S	1.306	1.00
449_D	452_T	1.302	1.00
156_V	160_D	1.299	1.00
195_G	199_A	1.298	1.00
72_N	75_A	1.293	1.00
434_E	438_A	1.291	1.00
104_Y	108_T	1.287	1.00
294_D	298_S	1.287	1.00
245_E	249_A	1.284	1.00
98_L	101_D	1.280	1.00
256_S	260_E	1.275	1.00
252_Q	256_S	1.274	1.00
302_A	305_N	1.267	1.00
173_I	192_T	1.266	1.00
285_M	393_D	1.263	1.00
103_V	106_D	1.263	1.00
445_D	449_D	1.259	1.00
102_Y	109_V	1.258	1.00
382_T	385_V	1.258	1.00
282_A	401_A	1.249	1.00
159_L	187_I	1.248	1.00
276_S	406_E	1.246	1.00
406_E	410_T	1.246	1.00
92_D	96_A	1.245	1.00
66_G	69_A	1.241	1.00
111_G	114_D	1.237	1.00
154_E	172_D	1.236	1.00
259_D	263_D	1.234	1.00
124_H	127_E	1.224	1.00
239_T	242_T	1.221	1.00
218_A	221_E	1.220	1.00
332_S	350_E	1.217	1.00
293_A	391_I	1.200	1.00
361_S	364_G	1.200	1.00
456_D	459_S	1.192	1.00
78_P	82_H	1.188	1.00
271_L	274_D	1.188	1.00
155_L	191_L	1.185	1.00
105_E	109_V	1.182	1.00
291_T	295_S	1.182	1.00
232_A	235_T	1.179	1.00
298_S	302_A	1.178	1.00
307_I	377_T	1.176	1.00
459_S	463_A	1.175	1.00
103_V	107_T	1.171	1.00
290_A	395_V	1.161	1.00
104_Y	107_T	1.156	1.00
441_D	445_D	1.156	1.00
287_A	291_T	1.155	1.00
203_T	207_N	1.150	1.00
175_A	182_D	1.148	1.00
214_A	218_A	1.148	1.00
231_T	235_T	1.148	1.00
125_T	128_F	1.140	1.00
197_T	200_A	1.139	1.00
259_D	427_N	1.138	1.00
204_E	207_N	1.137	1.00
65_D	69_A	1.125	1.00
298_S	301_E	1.125	1.00
309_D	372_E	1.120	1.00
225_E	228_E	1.118	1.00
164_A	193_E	1.114	1.00
300_V	384_L	1.107	1.00
173_I	188_G	1.107	1.00
452_T	456_D	1.106	1.00
294_D	392_E	1.104	1.00
301_E	385_V	1.104	1.00
371_S	375_R	1.104	1.00
171_V	192_T	1.104	1.00
291_T	294_D	1.102	1.00
318_T	363_A	1.100	1.00
299_D	383_D	1.097	1.00
235_T	239_T	1.093	1.00
270_R	273_D	1.092	1.00
410_T	414_A	1.091	1.00
274_D	400_D	1.087	1.00
71_A	75_A	1.085	1.00
110_A	114_D	1.084	1.00
316_V	362_N	1.082	1.00
286_M	394_A	1.079	1.00
212_L	216_S	1.073	1.00
173_I	189_R	1.072	1.00
73_K	78_P	1.072	1.00
294_D	388_T	1.070	1.00
155_L	159_L	1.069	1.00
254_I	426_T	1.069	1.00
269_E	273_D	1.069	1.00
445_D	448_D	1.065	1.00
256_S	259_D	1.065	1.00
276_S	409_V	1.064	1.00
424_D	428_E	1.064	1.00
91_A	94_S	1.063	1.00
455_A	459_S	1.063	1.00
207_N	210_E	1.063	1.00
157_D	160_D	1.058	1.00
421_Q	424_D	1.056	1.00
158_T	171_V	1.056	1.00
207_N	211_R	1.055	1.00
161_A	164_A	1.053	1.00
82_H	86_D	1.053	1.00
246_T	249_A	1.051	1.00
276_S	280_S	1.048	1.00
304_Q	308_E	1.047	1.00
475_V	478_L	1.045	1.00
93_E	97_L	1.043	1.00
424_D	427_N	1.035	1.00
365_H	368_S	1.030	1.00
154_E	157_D	1.023	1.00
153_G	157_D	1.022	1.00
386_T	389_D	1.021	1.00
142_A	146_S	1.017	1.00
203_T	206_H	1.016	1.00
167_F	198_L	1.014	1.00
396_A	399_E	1.014	1.00
214_A	217_Q	1.013	1.00
368_S	372_E	1.012	1.00
63_N	67_S	1.009	1.00
438_A	442_E	1.007	1.00
390_R	393_D	1.002	1.00
274_D	407_E	1.001	1.00
264_T	414_A	1.001	1.00
210_E	214_A	0.999	1.00
229_L	233_Q	0.999	1.00
228_E	231_T	0.999	1.00
117_F	121_P	0.995	1.00
138_R	142_A	0.994	1.00
205_V	208_D	0.993	1.00
102_Y	105_E	0.993	1.00
364_G	367_E	0.992	1.00
252_Q	434_E	0.991	1.00
80_D	83_H	0.987	1.00
228_E	232_A	0.986	1.00
87_G	90_L	0.984	1.00
133_E	137_D	0.982	1.00
184_Y	188_G	0.982	1.00
382_T	386_T	0.981	1.00
397_Q	400_D	0.980	1.00
448_D	452_T	0.980	1.00
275_G	408_I	0.979	1.00
156_V	187_I	0.975	1.00
69_A	73_K	0.970	1.00
204_E	208_D	0.970	1.00
188_G	192_T	0.970	1.00
360_Q	364_G	0.968	1.00
358_D	361_S	0.968	1.00
139_S	143_R	0.968	1.00
238_S	242_T	0.965	1.00
171_V	188_G	0.965	1.00
115_L	119_A	0.962	1.00
304_Q	378_A	0.962	1.00
464_Q	478_L	0.961	1.00
92_D	95_Y	0.952	1.00
92_D	99_T	0.951	1.00
210_E	472_D	0.949	1.00
158_T	161_A	0.948	1.00
104_Y	109_V	0.942	1.00
152_F	184_Y	0.942	1.00
282_A	398_V	0.939	1.00
107_T	110_A	0.934	1.00
67_S	71_A	0.932	1.00
193_E	196_D	0.931	1.00
428_E	431_A	0.926	1.00
102_Y	108_T	0.926	1.00
169_A	195_G	0.925	1.00
268_A	412_V	0.925	1.00
269_E	416_A	0.925	1.00
97_L	100_G	0.923	1.00
89_G	93_E	0.920	1.00
474_S	477_E	0.920	1.00
438_A	441_D	0.918	1.00
275_G	405_F	0.916	1.00
466_A	469_H	0.914	1.00
297_T	388_T	0.910	1.00
94_S	97_L	0.909	1.00
154_E	158_T	0.909	1.00
368_S	371_S	0.907	1.00
147_E	151_L	0.906	1.00
172_D	192_T	0.905	1.00
279_A	401_A	0.903	1.00
158_T	169_A	0.902	1.00
162_Y	191_L	0.902	1.00
297_T	385_V	0.900	1.00
375_R	379_D	0.899	1.00
152_F	187_I	0.898	1.00
64_D	68_R	0.898	1.00
242_T	246_T	0.897	1.00
417_E	421_Q	0.896	1.00
271_L	411_A	0.894	1.00
89_G	92_D	0.894	1.00
121_P	124_H	0.894	1.00
332_S	353_K	0.893	1.00
221_E	224_A	0.892	1.00
116_W	120_T	0.883	1.00
232_A	236_N	0.883	1.00
217_Q	221_E	0.882	1.00
151_L	184_Y	0.881	1.00
247_L	433_A	0.878	1.00
288_D	291_T	0.878	1.00
71_A	74_V	0.877	1.00
300_V	381_V	0.877	1.00
96_A	100_G	0.874	1.00
309_D	369_L	0.869	1.00
260_E	418_G	0.867	1.00
313_V	369_L	0.867	1.00
292_A	295_S	0.867	1.00
145_Q	148_L	0.863	1.00
302_A	306_R	0.863	1.00
116_W	119_A	0.858	1.00
249_A	253_E	0.857	1.00
73_K	81_A	0.856	1.00
405_F	408_I	0.853	1.00
64_D	67_S	0.848	1.00
181_D	185_I	0.847	1.00
193_E	197_T	0.846	1.00
226_I	229_L	0.842	1.00
212_L	215_A	0.841	1.00
191_L	194_F	0.838	1.00
267_T	411_A	0.834	1.00
157_D	161_A	0.833	1.00
114_D	118_I	0.832	1.00
289_V	391_I	0.831	1.00
269_E	413_E	0.831	1.00
281_D	393_D	0.829	1.00
217_Q	465_S	0.829	1.00
233_Q	247_L	0.826	1.00
189_R	192_T	0.826	1.00
213_E	217_Q	0.825	1.00
459_S	462_E	0.819	1.00
169_A	173_I	0.818	1.00
402_M	406_E	0.818	1.00
131_V	135_V	0.817	1.00
137_D	141_S	0.815	1.00
290_A	392_E	0.814	1.00
296_V	383_D	0.813	1.00
233_Q	243_E	0.811	1.00
80_D	84_E	0.811	1.00
462_E	465_S	0.811	1.00
143_R	146_S	0.810	1.00
70_L	74_V	0.809	1.00
161_A	194_F	0.809	1.00
266_A	420_E	0.805	1.00
409_V	413_E	0.800	1.00
96_A	99_T	0.800	1.00
308_E	378_A	0.800	1.00
245_E	437_A	0.797	1.00
74_V	77_T	0.795	1.00
296_V	387_T	0.795	1.00
79_I	83_H	0.795	1.00
88_V	91_A	0.793	1.00
472_D	476_S	0.792	1.00
465_S	469_H	0.790	1.00
108_T	111_G	0.789	1.00
233_Q	240_V	0.788	1.00
285_M	390_R	0.784	1.00
267_T	271_L	0.782	1.00
105_E	108_T	0.782	1.00
473_E	476_S	0.780	1.00
159_L	162_Y	0.779	1.00
158_T	191_L	0.778	1.00
150_A	154_E	0.778	1.00
358_D	365_H	0.777	1.00
287_A	395_V	0.773	1.00
295_S	383_D	0.772	1.00
285_M	397_Q	0.769	1.00
211_R	214_A	0.769	1.00
431_A	435_E	0.768	1.00
205_V	209_V	0.767	1.00
379_D	382_T	0.764	1.00
227_D	231_T	0.762	1.00
65_D	68_R	0.760	1.00
296_V	384_L	0.758	1.00
319_G	358_D	0.756	1.00
318_T	322_E	0.755	1.00
420_E	424_D	0.754	1.00
77_T	82_H	0.746	1.00
149_Q	153_G	0.745	1.00
153_G	186_Q	0.742	1.00
111_G	115_L	0.739	1.00
302_A	379_D	0.738	1.00
202_I	205_V	0.738	1.00
288_D	292_A	0.737	1.00
236_N	439_M	0.736	1.00
262_V	266_A	0.735	1.00
417_E	420_E	0.735	1.00
125_T	129_R	0.730	1.00
106_D	111_G	0.728	1.00
297_T	301_E	0.726	1.00
257_T	421_Q	0.725	1.00
106_D	109_V	0.725	1.00
388_T	392_E	0.724	1.00
148_L	151_L	0.721	1.00
280_S	402_M	0.720	1.00
244_V	440_V	0.719	1.00
197_T	477_E	0.719	1.00
62_L	65_D	0.718	1.00
286_M	289_V	0.714	1.00
253_E	421_Q	0.712	1.00
329_L	337_R	0.712	1.00
399_E	402_M	0.711	1.00
247_L	429_Q	0.711	1.00
223_S	454_V	0.711	1.00
74_V	78_P	0.710	1.00
322_E	360_Q	0.709	1.00
312_E	316_V	0.707	1.00
288_D	393_D	0.702	1.00
307_I	373_I	0.702	1.00
319_G	322_E	0.702	1.00
273_D	276_S	0.701	1.00
149_Q	184_Y	0.701	1.00
173_I	185_I	0.701	1.00
112_N	115_L	0.698	1.00
242_T	245_E	0.696	1.00
375_R	378_A	0.695	1.00
287_A	290_A	0.695	1.00
92_D	98_L	0.694	1.00
249_A	252_Q	0.694	1.00
279_A	398_V	0.694	1.00
200_A	203_T	0.693	1.00
163_D	193_E	0.692	1.00
350_E	354_A	0.692	1.00
67_S	70_L	0.692	1.00
261_V	418_G	0.691	1.00
151_L	183_E	0.690	1.00
467_M	470_D	0.689	1.00
273_D	409_V	0.686	1.00
410_T	413_E	0.686	1.00
201_H	205_V	0.686	1.00
226_I	233_Q	0.686	1.00
67_S	74_V	0.682	1.00
446_L	450_I	0.680	1.00
293_A	387_T	0.678	1.00
303_L	373_I	0.678	1.00
278_A	404_S	0.678	1.00
167_F	202_I	0.677	1.00
204_E	474_S	0.677	1.00
81_A	85_Y	0.677	1.00
281_D	285_M	0.676	1.00
308_E	312_E	0.674	1.00
194_F	198_L	0.673	1.00
92_D	97_L	0.673	1.00
89_G	96_A	0.669	1.00
89_G	94_S	0.664	1.00
94_S	101_D	0.663	1.00
314_V	367_E	0.662	1.00
434_E	437_A	0.661	1.00
232_A	442_E	0.661	1.00
95_Y	99_T	0.659	1.00
278_A	281_D	0.658	1.00
452_T	459_S	0.655	1.00
435_E	439_M	0.654	1.00
163_D	190_N	0.654	1.00
251_V	426_T	0.652	1.00
158_T	162_Y	0.652	1.00
280_S	406_E	0.649	1.00
295_S	299_D	0.649	1.00
248_S	433_A	0.649	1.00
312_E	365_H	0.647	1.00
314_V	318_T	0.646	1.00
135_V	139_S	0.645	1.00
318_T	364_G	0.645	1.00
471_L	478_L	0.642	1.00
444_A	448_D	0.642	1.00
233_Q	236_N	0.636	1.00
225_E	449_D	0.636	1.00
81_A	84_E	0.636	1.00
191_L	195_G	0.634	1.00
310_I	370_V	0.633	1.00
243_E	246_T	0.633	1.00
414_A	418_G	0.632	1.00
93_E	96_A	0.630	1.00
453_A	456_D	0.629	1.00
182_D	188_G	0.629	1.00
374_Q	378_A	0.629	1.00
301_E	304_Q	0.629	1.00
457_I	460_Q	0.629	1.00
150_A	153_G	0.628	1.00
87_G	91_A	0.626	1.00
218_A	460_Q	0.626	1.00
156_V	184_Y	0.624	1.00
372_E	376_D	0.624	1.00
118_I	122_V	0.621	1.00
262_V	420_E	0.618	1.00
201_H	204_E	0.617	1.00
293_A	296_V	0.614	1.00
211_R	463_A	0.610	1.00
431_A	434_E	0.610	1.00
94_S	99_T	0.610	1.00
240_V	439_M	0.609	1.00
464_Q	468_L	0.609	1.00
88_V	94_S	0.607	1.00
299_D	376_D	0.607	1.00
90_L	93_E	0.606	1.00
236_N	239_T	0.606	1.00
313_V	362_N	0.605	1.00
428_E	432_S	0.603	1.00
113_T	116_W	0.603	1.00
118_I	121_P	0.602	1.00
155_L	158_T	0.602	1.00
91_A	97_L	0.599	1.00
248_S	251_V	0.595	1.00
226_I	454_V	0.595	1.00
227_D	455_A	0.592	1.00
77_T	80_D	0.592	1.00
73_K	77_T	0.591	1.00
353_K	357_E	0.590	1.00
87_G	92_D	0.590	1.00
377_T	380_T	0.589	1.00
460_Q	463_A	0.589	1.00
272_A	276_S	0.587	1.00
391_I	394_A	0.586	1.00
307_I	313_V	0.586	1.00
209_V	213_E	0.586	1.00
226_I	230_S	0.584	1.00
290_A	294_D	0.583	1.00
111_G	116_W	0.582	1.00
325_N	353_K	0.581	1.00
98_L	105_E	0.581	1.00
83_H	86_D	0.580	1.00
315_D	318_T	0.580	1.00
240_V	436_I	0.578	1.00
323_Q	351_E	0.576	1.00
313_V	370_V	0.576	1.00
114_D	117_F	0.575	1.00
104_Y	111_G	0.574	1.00
90_L	94_S	0.573	1.00
283_A	287_A	0.573	1.00
303_L	380_T	0.573	1.00
88_V	95_Y	0.572	1.00
238_S	444_A	0.570	1.00
240_V	440_V	0.565	1.00
272_A	275_G	0.564	1.00
91_A	96_A	0.563	1.00
437_A	441_D	0.563	1.00
268_A	411_A	0.563	1.00
147_E	150_A	0.560	1.00
356_A	359_A	0.560	1.00
240_V	244_V	0.558	1.00
164_A	197_T	0.558	1.00
237_V	443_T	0.558	1.00
165_G	194_F	0.557	1.00
216_S	461_T	0.556	1.00
205_V	475_V	0.556	1.00
423_S	426_T	0.555	1.00
158_T	195_G	0.554	1.00
407_E	411_A	0.553	1.00
75_A	79_I	0.552	1.00
213_E	216_S	0.552	1.00
278_A	397_Q	0.549	1.00
165_G	201_H	0.548	1.00
265_S	412_V	0.548	1.00
422_V	425_A	0.545	1.00
244_V	247_L	0.543	1.00
248_S	437_A	0.542	1.00
132_I	139_S	0.541	1.00
463_A	467_M	0.541	1.00
73_K	76_D	0.540	1.00
377_T	381_V	0.538	1.00
154_E	173_I	0.538	1.00
380_T	384_L	0.537	1.00
279_A	282_A	0.534	1.00
185_I	189_R	0.532	1.00
313_V	316_V	0.532	1.00
468_L	478_L	0.530	1.00
295_S	386_T	0.528	1.00
297_T	384_L	0.526	1.00
293_A	384_L	0.525	1.00
128_F	131_V	0.524	1.00
279_A	405_F	0.524	1.00
155_L	184_Y	0.523	1.00
126_G	130_G	0.523	1.00
274_D	404_S	0.522	1.00
285_M	288_D	0.521	1.00
69_A	87_G	0.518	1.00
264_T	267_T	0.518	1.00
286_M	398_V	0.516	1.00
288_D	386_T	0.513	1.00
134_I	137_D	0.512	1.00
371_S	374_Q	0.510	1.00
398_V	402_M	0.508	1.00
123_Y	126_G	0.508	1.00
218_A	456_D	0.506	1.00
81_A	86_D	0.505	1.00
234_S	448_D	0.505	1.00
241_A	244_V	0.504	1.00
70_L	85_Y	0.503	1.00
68_R	71_A	0.501	1.00
222_S	453_A	0.501	1.00
132_I	136_Q	0.500	1.00

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
3zx6A	2	0.632	100	0.332	Contact Map
2ch7A	2	0.6133	100	0.473	Contact Map
1qu7A	2	0.4678	100	0.477	Contact Map
3g67A	2	0.4345	100	0.555	Contact Map
4i3mA	2	0.3056	99.9	0.724	Contact Map
4cq4A	4	0.1788	99.4	0.832	Contact Map
2f95B	2	0.1019	99.3	0.84	Contact Map
4gycB	2	0.1247	99.1	0.851	Contact Map
3zccA	2	0.2204	98.8	0.868	Contact Map
4i5sA	2	0.5904	98.3	0.886	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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