RAD25 - HALSA - GREMLIN Contacts

Home
GREMLIN
- Submit - Monomer
- Submit - Complex
Contacts
Metagenomics
- Contacts
- Structures
Structures
- List
Old Projects
- Complexes (2014)
- PFAM (2013)

RAD25 - Putative DNA helicase Rad25

UniProt:	Q9HPZ2	Sequences: MTDISKDRFLDALEGVGRPVATAEQIARELDCTQATAADALAALAADDEVERANVEPDPVVWYPRDWLELTDRERIVPFPDRREIIVDQPSQLTRAQLSRVAHLTDTTRTGSYRYEVRAEDVWAAPFDSLSDLVAAITELLPRDCPTLIEWVREQWTRATRFRLRTHDDGYVVLEAATDSLLGNVAEQKLDDDVLRAPISDTEAWVAAEQVAPLKRTLYEAGYPVRDDRDLESGEPLAVDLHLDLRPYQQDWVDRFEDASAGVLVGPPGSGKTVAAMGALESVGGETLVLVPSRELATQWREELLANTSLTGDQIGEYHGGEKRVRPVTIATYQTAGMDRHRHVFDDREWGLIVYDEVHHIPAEVARRSASLQSKHRLGLTATPVREDDKEADIYTLVGRPIGTDWDALFDAGFVAEPEVEIRYVPWRDDDDRYEYAAASGHTRRRLAAENPAKEAEIEHLVDQHGDTQALVFVDYLSQGERIAERLDAPFVNGETPHSRRETHFDQFRTGALDALVVSRIGDEGIDLPDAEFAVVASGLGGSRRQGAQRAGRTMRPGSQSLLFVLATRGTEEEDHARSRMRHLSTKGVRVTESDASHSP	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	600 (501)
Sequences:	5949 (5030)
Seq/√Len:	224.7

ECOLI - DEAD RAPA RECQ RECG YFJK YEJH RHLE DBPA RHLB SRMB
BACSU - YWQA RECG RECQ YPRA CSHA RECS COMFA DBPA YQHH CSHB
HALSA - RAD25 O52003 Q9HNB2 O51997 Q9HMW5 HELS Q9HN80
SULSO - Q97ZF9 Q97X74 Q981C8 Q97ZV2 HELS HELX Q97YC4

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
366_A	369_S	3.315	1.00
365_V	369_S	3.174	1.00
168_D	171_Y	3.141	1.00
304_L	328_V	2.936	1.00
468_T	532_E	2.913	1.00
277_M	304_L	2.707	1.00
367_R	370_A	2.621	1.00
238_A	241_L	2.580	1.00
160_T	163_R	2.487	1.00
515_A	518_V	2.460	1.00
80_P	84_E	2.293	1.00
462_V	470_A	2.284	1.00
358_V	379_G	2.268	1.00
405_D	408_A	2.142	1.00
138_T	141_L	2.114	1.00
192_D	195_L	2.073	1.00
80_P	83_R	2.052	1.00
365_V	370_A	2.033	1.00
85_I	89_Q	2.003	1.00
99_S	102_A	1.978	1.00
133_L	137_I	1.971	1.00
83_R	87_V	1.968	1.00
481_E	491_F	1.956	1.00
228_D	231_L	1.956	1.00
70_L	73_R	1.948	1.00
76_I	79_F	1.944	1.00
221_A	224_P	1.941	1.00
74_E	78_P	1.935	1.00
252_W	275_A	1.927	1.00
214_L	218_L	1.914	1.00
182_L	186_A	1.911	1.00
178_T	182_L	1.890	1.00
237_L	240_D	1.869	1.00
194_V	197_A	1.856	1.00
222_G	228_D	1.818	1.00
141_L	144_D	1.817	1.00
58_D	62_W	1.816	1.00
64_P	67_W	1.811	1.00
183_G	186_A	1.807	1.00
76_I	80_P	1.805	1.00
60_V	64_P	1.800	1.00
302_E	506_D	1.791	1.00
77_V	80_P	1.787	1.00
62_W	66_D	1.776	1.00
568_T	571_T	1.776	1.00
94_T	97_Q	1.775	1.00
66_D	70_L	1.766	1.00
222_G	225_V	1.761	1.00
165_R	168_D	1.756	1.00
211_V	218_L	1.756	1.00
193_D	196_R	1.752	1.00
218_L	222_G	1.750	1.00
366_A	370_A	1.749	1.00
97_Q	100_R	1.746	1.00
124_A	127_F	1.738	1.00
320_G	325_V	1.736	1.00
66_D	69_E	1.721	1.00
73_R	76_I	1.720	1.00
218_L	221_A	1.712	1.00
63_Y	66_D	1.711	1.00
104_L	107_T	1.707	1.00
81_D	84_E	1.700	1.00
534_A	554_T	1.690	1.00
177_A	180_S	1.683	1.00
497_P	500_R	1.667	1.00
367_R	371_S	1.664	1.00
79_F	83_R	1.648	1.00
71_T	74_E	1.646	1.00
62_W	65_R	1.645	1.00
131_S	134_V	1.645	1.00
67_W	70_L	1.642	1.00
118_R	122_V	1.623	1.00
105_T	108_T	1.620	1.00
222_G	226_R	1.613	1.00
98_L	102_A	1.610	1.00
318_Y	341_H	1.601	1.00
57_P	61_V	1.587	1.00
116_E	119_A	1.574	1.00
472_V	535_V	1.570	1.00
459_E	486_R	1.568	1.00
178_T	181_L	1.565	1.00
67_W	71_T	1.563	1.00
474_V	480_G	1.554	1.00
93_L	96_A	1.553	1.00
137_I	140_L	1.551	1.00
63_Y	67_W	1.550	1.00
214_L	217_T	1.547	1.00
64_P	68_L	1.542	1.00
458_I	462_V	1.541	1.00
221_A	225_V	1.525	1.00
210_Q	214_L	1.525	1.00
222_G	227_D	1.522	1.00
193_D	197_A	1.521	1.00
73_R	77_V	1.509	1.00
94_T	98_L	1.504	1.00
514_D	518_V	1.499	1.00
296_L	525_G	1.498	1.00
82_R	86_I	1.498	1.00
122_V	125_A	1.497	1.00
65_R	68_L	1.492	1.00
87_V	91_S	1.488	1.00
211_V	214_L	1.477	1.00
83_R	86_I	1.477	1.00
166_T	169_D	1.468	1.00
74_E	77_V	1.465	1.00
132_D	135_A	1.464	1.00
100_R	104_L	1.462	1.00
490_P	507_Q	1.461	1.00
167_H	170_G	1.451	1.00
191_D	194_V	1.451	1.00
137_I	142_P	1.451	1.00
59_P	62_W	1.449	1.00
78_P	81_D	1.447	1.00
72_D	78_P	1.446	1.00
134_V	138_T	1.437	1.00
72_D	76_I	1.435	1.00
58_D	61_V	1.431	1.00
63_Y	68_L	1.429	1.00
81_D	85_I	1.427	1.00
158_R	161_R	1.419	1.00
61_V	64_P	1.413	1.00
181_L	184_N	1.411	1.00
176_A	179_D	1.406	1.00
96_A	100_R	1.404	1.00
79_F	82_R	1.402	1.00
474_V	483_I	1.398	1.00
72_D	75_R	1.397	1.00
166_T	170_G	1.394	1.00
152_V	155_Q	1.379	1.00
93_L	97_Q	1.376	1.00
61_V	65_R	1.371	1.00
75_R	79_F	1.370	1.00
65_R	69_E	1.366	1.00
60_V	63_Y	1.364	1.00
219_Y	225_V	1.360	1.00
223_Y	226_R	1.358	1.00
155_Q	158_R	1.357	1.00
141_L	145_C	1.355	1.00
359_H	524_E	1.355	1.00
172_V	176_A	1.353	1.00
120_E	123_W	1.353	1.00
148_L	151_W	1.350	1.00
96_A	101_V	1.350	1.00
484_A	489_A	1.350	1.00
98_L	101_V	1.349	1.00
71_T	75_R	1.345	1.00
228_D	233_S	1.341	1.00
132_D	136_A	1.338	1.00
142_P	145_C	1.334	1.00
490_P	504_H	1.321	1.00
149_I	152_V	1.321	1.00
122_V	127_F	1.315	1.00
417_E	422_I	1.315	1.00
139_E	142_P	1.314	1.00
75_R	78_P	1.312	1.00
229_R	234_G	1.309	1.00
83_R	88_D	1.306	1.00
78_P	82_R	1.302	1.00
171_Y	174_L	1.298	1.00
121_D	124_A	1.298	1.00
118_R	121_D	1.294	1.00
102_A	105_T	1.289	1.00
423_R	426_P	1.289	1.00
226_R	231_L	1.287	1.00
212_A	217_T	1.285	1.00
174_L	177_A	1.283	1.00
124_A	128_D	1.274	1.00
217_T	221_A	1.273	1.00
319_H	322_E	1.273	1.00
161_R	164_L	1.269	1.00
217_T	220_E	1.265	1.00
428_R	445_R	1.264	1.00
90_P	93_L	1.263	1.00
483_I	537_A	1.261	1.00
116_E	120_E	1.254	1.00
509_R	530_D	1.252	1.00
406_W	409_L	1.251	1.00
211_V	219_Y	1.251	1.00
142_P	146_P	1.249	1.00
232_E	235_E	1.246	1.00
218_L	223_Y	1.246	1.00
130_L	133_L	1.245	1.00
159_A	164_L	1.243	1.00
64_P	70_L	1.243	1.00
301_R	305_L	1.242	1.00
227_D	231_L	1.241	1.00
71_T	77_V	1.240	1.00
173_V	176_A	1.238	1.00
82_R	85_I	1.234	1.00
85_I	88_D	1.224	1.00
169_D	172_V	1.216	1.00
216_R	219_Y	1.214	1.00
182_L	185_V	1.213	1.00
98_L	105_T	1.210	1.00
84_E	87_V	1.209	1.00
69_E	75_R	1.206	1.00
113_Y	116_E	1.204	1.00
238_A	242_H	1.202	1.00
219_Y	223_Y	1.198	1.00
170_G	174_L	1.196	1.00
206_V	209_E	1.193	1.00
193_D	198_P	1.187	1.00
78_P	84_E	1.187	1.00
204_A	207_A	1.182	1.00
457_E	461_L	1.181	1.00
297_A	330_I	1.181	1.00
99_S	103_H	1.179	1.00
477_L	495_E	1.179	1.00
173_V	182_L	1.176	1.00
86_I	89_Q	1.175	1.00
173_V	177_A	1.173	1.00
533_F	564_F	1.173	1.00
188_Q	191_D	1.172	1.00
190_L	193_D	1.166	1.00
219_Y	222_G	1.163	1.00
60_V	68_L	1.161	1.00
66_D	75_R	1.160	1.00
149_I	153_R	1.155	1.00
280_L	287_T	1.155	1.00
257_E	282_S	1.153	1.00
148_L	152_V	1.150	1.00
156_W	160_T	1.150	1.00
96_A	99_S	1.149	1.00
69_E	73_R	1.148	1.00
230_D	233_S	1.147	1.00
137_I	146_P	1.145	1.00
175_E	178_T	1.144	1.00
503_T	507_Q	1.139	1.00
136_A	139_E	1.137	1.00
130_L	134_V	1.137	1.00
213_P	225_V	1.134	1.00
174_L	178_T	1.129	1.00
154_E	158_R	1.128	1.00
176_A	180_S	1.127	1.00
92_Q	97_Q	1.125	1.00
69_E	77_V	1.124	1.00
150_E	153_R	1.122	1.00
194_V	198_P	1.121	1.00
413_G	418_P	1.120	1.00
213_P	218_L	1.119	1.00
222_G	229_R	1.119	1.00
93_L	98_L	1.112	1.00
419_E	422_I	1.111	1.00
85_I	90_P	1.108	1.00
125_A	128_D	1.107	1.00
122_V	128_D	1.106	1.00
121_D	126_P	1.106	1.00
231_L	234_G	1.106	1.00
317_E	320_G	1.106	1.00
77_V	81_D	1.104	1.00
461_L	564_F	1.103	1.00
115_Y	126_P	1.100	1.00
421_E	424_Y	1.096	1.00
68_L	71_T	1.095	1.00
133_L	136_A	1.095	1.00
237_L	242_H	1.095	1.00
138_T	145_C	1.092	1.00
95_R	101_V	1.091	1.00
224_P	227_D	1.085	1.00
114_R	118_R	1.078	1.00
195_L	198_P	1.070	1.00
405_D	409_L	1.069	1.00
214_L	222_G	1.067	1.00
153_R	156_W	1.065	1.00
225_V	228_D	1.063	1.00
147_T	150_E	1.063	1.00
536_V	539_G	1.059	1.00
457_E	460_H	1.055	1.00
147_T	152_V	1.055	1.00
551_A	563_L	1.053	1.00
73_R	80_P	1.052	1.00
159_A	162_F	1.052	1.00
418_P	421_E	1.051	1.00
175_E	181_L	1.051	1.00
214_L	219_Y	1.043	1.00
203_E	206_V	1.039	1.00
79_F	89_Q	1.036	1.00
136_A	140_L	1.035	1.00
104_L	108_T	1.034	1.00
61_V	66_D	1.032	1.00
59_P	67_W	1.031	1.00
170_G	173_V	1.031	1.00
137_I	145_C	1.029	1.00
191_D	195_L	1.029	1.00
60_V	66_D	1.029	1.00
355_Y	361_I	1.027	1.00
157_T	160_T	1.022	1.00
88_D	91_S	1.021	1.00
155_Q	162_F	1.019	1.00
183_G	187_E	1.018	1.00
303_E	306_A	1.014	1.00
141_L	146_P	1.012	1.00
225_V	230_D	1.011	1.00
172_V	175_E	1.006	1.00
101_V	104_L	1.003	1.00
454_K	461_L	1.003	1.00
138_T	143_R	1.001	1.00
218_L	224_P	1.000	1.00
414_F	418_P	0.997	1.00
151_W	155_Q	0.995	1.00
236_P	240_D	0.994	1.00
97_Q	103_H	0.993	1.00
63_Y	69_E	0.991	1.00
176_A	182_L	0.989	1.00
454_K	462_V	0.987	1.00
394_I	397_L	0.985	1.00
57_P	60_V	0.984	1.00
175_E	182_L	0.983	1.00
87_V	90_P	0.982	1.00
100_R	107_T	0.980	1.00
205_W	209_E	0.979	1.00
137_I	141_L	0.979	1.00
69_E	72_D	0.979	1.00
212_A	215_K	0.978	1.00
134_V	141_L	0.974	1.00
74_E	79_F	0.973	1.00
156_W	159_A	0.972	1.00
112_S	115_Y	0.971	1.00
114_R	117_V	0.970	1.00
156_W	161_R	0.968	1.00
450_E	454_K	0.963	1.00
226_R	234_G	0.963	1.00
413_G	416_A	0.960	1.00
167_H	171_Y	0.958	1.00
179_D	183_G	0.952	1.00
112_S	116_E	0.951	1.00
69_E	81_D	0.951	1.00
119_A	123_W	0.947	1.00
180_S	183_G	0.945	1.00
227_D	232_E	0.943	1.00
65_R	73_R	0.942	1.00
206_V	210_Q	0.940	1.00
274_V	277_M	0.937	1.00
152_V	158_R	0.937	1.00
152_V	157_T	0.934	1.00
253_V	278_G	0.933	1.00
136_A	144_D	0.933	1.00
169_D	173_V	0.932	1.00
159_A	163_R	0.932	1.00
581_M	584_L	0.932	1.00
116_E	122_V	0.930	1.00
92_Q	96_A	0.926	1.00
118_R	124_A	0.924	1.00
209_E	224_P	0.921	1.00
237_L	241_L	0.921	1.00
280_L	313_D	0.918	0.99
494_G	501_R	0.918	0.99
223_Y	227_D	0.917	0.99
92_Q	98_L	0.917	0.99
207_A	210_Q	0.917	0.99
86_I	91_S	0.916	0.99
157_T	161_R	0.913	0.99
96_A	106_D	0.912	0.99
61_V	71_T	0.910	0.99
115_Y	118_R	0.910	0.99
198_P	202_T	0.910	0.99
218_L	228_D	0.907	0.99
210_Q	213_P	0.907	0.99
136_A	142_P	0.905	0.99
468_T	533_F	0.904	0.99
461_L	465_H	0.904	0.99
211_V	222_G	0.902	0.99
114_R	122_V	0.897	0.99
70_L	76_I	0.896	0.99
245_L	249_Q	0.894	0.99
117_V	121_D	0.894	0.99
334_Q	360_H	0.894	0.99
134_V	137_I	0.892	0.99
217_T	227_D	0.889	0.99
579_S	582_R	0.889	0.99
228_D	234_G	0.889	0.99
172_V	177_A	0.887	0.99
119_A	122_V	0.887	0.99
393_D	397_L	0.887	0.99
122_V	126_P	0.884	0.99
224_P	230_D	0.883	0.99
215_K	219_Y	0.883	0.99
67_W	73_R	0.880	0.99
79_F	86_I	0.878	0.99
81_D	89_Q	0.873	0.99
160_T	164_L	0.872	0.99
139_E	145_C	0.868	0.99
97_Q	101_V	0.867	0.99
123_W	126_P	0.866	0.99
102_A	106_D	0.861	0.99
140_L	143_R	0.860	0.99
96_A	104_L	0.859	0.99
129_S	132_D	0.857	0.99
76_I	84_E	0.856	0.99
207_A	211_V	0.856	0.99
276_A	354_V	0.854	0.99
62_W	74_E	0.852	0.99
94_T	102_A	0.852	0.99
117_V	128_D	0.850	0.99
111_G	114_R	0.849	0.99
450_E	457_E	0.849	0.99
195_L	202_T	0.847	0.99
204_A	214_L	0.845	0.99
211_V	223_Y	0.844	0.99
82_R	90_P	0.844	0.99
130_L	136_A	0.841	0.99
208_A	215_K	0.840	0.99
181_L	186_A	0.839	0.99
150_E	154_E	0.837	0.99
135_A	138_T	0.837	0.99
234_G	238_A	0.835	0.99
98_L	104_L	0.832	0.99
67_W	72_D	0.828	0.99
134_V	140_L	0.827	0.99
80_P	88_D	0.826	0.99
180_S	184_N	0.824	0.99
578_R	585_S	0.823	0.99
78_P	86_I	0.821	0.99
484_A	491_F	0.820	0.99
136_A	145_C	0.820	0.99
206_V	211_V	0.820	0.99
155_Q	161_R	0.819	0.99
132_D	137_I	0.819	0.99
120_E	126_P	0.818	0.99
181_L	185_V	0.818	0.99
121_D	125_A	0.813	0.99
214_L	221_A	0.811	0.99
179_D	182_L	0.811	0.99
188_Q	193_D	0.810	0.99
213_P	217_T	0.809	0.99
215_K	221_A	0.808	0.99
68_L	72_D	0.807	0.99
217_T	222_G	0.804	0.99
113_Y	117_V	0.804	0.99
474_V	517_V	0.803	0.99
75_R	82_R	0.802	0.99
101_V	105_T	0.802	0.99
146_P	150_E	0.798	0.99
191_D	197_A	0.798	0.99
225_V	229_R	0.797	0.99
72_D	81_D	0.796	0.99
205_W	211_V	0.796	0.99
222_G	230_D	0.796	0.99
150_E	155_Q	0.795	0.99
205_W	214_L	0.794	0.99
95_R	103_H	0.792	0.99
182_L	187_E	0.792	0.99
57_P	63_Y	0.791	0.99
167_H	173_V	0.789	0.98
301_R	330_I	0.786	0.98
135_A	139_E	0.786	0.98
207_A	213_P	0.785	0.98
139_E	146_P	0.784	0.98
155_Q	159_A	0.782	0.98
212_A	221_A	0.782	0.98
154_E	157_T	0.782	0.98
222_G	231_L	0.782	0.98
469_Q	530_D	0.781	0.98
148_L	155_Q	0.781	0.98
226_R	229_R	0.780	0.98
84_E	89_Q	0.778	0.98
143_R	151_W	0.774	0.98
93_L	100_R	0.773	0.98
139_E	143_R	0.773	0.98
211_V	215_K	0.773	0.98
131_S	135_A	0.772	0.98
59_P	65_R	0.771	0.98
218_L	233_S	0.770	0.98
220_E	226_R	0.770	0.98
95_R	98_L	0.768	0.98
222_G	234_G	0.766	0.98
208_A	216_R	0.766	0.98
581_M	585_S	0.766	0.98
62_W	70_L	0.766	0.98
190_L	195_L	0.765	0.98
70_L	75_R	0.764	0.98
67_W	75_R	0.762	0.98
293_S	334_Q	0.762	0.98
171_Y	175_E	0.761	0.98
84_E	88_D	0.759	0.98
141_L	151_W	0.758	0.98
77_V	87_V	0.757	0.98
130_L	137_I	0.755	0.98
210_Q	215_K	0.755	0.98
157_T	163_R	0.755	0.98
96_A	102_A	0.752	0.98
168_D	184_N	0.750	0.98
92_Q	95_R	0.750	0.98
219_Y	228_D	0.750	0.98
225_V	231_L	0.747	0.98
536_V	540_L	0.747	0.98
115_Y	119_A	0.747	0.98
184_N	187_E	0.747	0.98
461_L	535_V	0.746	0.98
221_A	227_D	0.743	0.98
231_L	235_E	0.742	0.98
153_R	157_T	0.742	0.98
85_I	91_S	0.740	0.98
147_T	151_W	0.738	0.98
513_L	516_L	0.737	0.98
211_V	216_R	0.736	0.98
71_T	78_P	0.736	0.98
154_E	160_T	0.734	0.98
170_G	178_T	0.733	0.98
188_Q	192_D	0.731	0.98
204_A	209_E	0.729	0.97
117_V	120_E	0.729	0.97
417_E	420_V	0.728	0.97
296_L	299_Q	0.728	0.97
170_G	175_E	0.726	0.97
89_Q	92_Q	0.726	0.97
129_S	133_L	0.725	0.97
230_D	235_E	0.724	0.97
263_V	394_I	0.721	0.97
70_L	74_E	0.720	0.97
94_T	105_T	0.718	0.97
138_T	144_D	0.718	0.97
256_F	378_L	0.717	0.97
190_L	194_V	0.716	0.97
209_E	214_L	0.714	0.97
207_A	216_R	0.714	0.97
66_D	76_I	0.714	0.97
70_L	85_I	0.713	0.97
207_A	219_Y	0.712	0.97
226_R	230_D	0.711	0.97
94_T	101_V	0.711	0.97
165_R	169_D	0.710	0.97
86_I	90_P	0.709	0.97
134_V	139_E	0.708	0.97
102_A	108_T	0.708	0.97
132_D	139_E	0.707	0.97
74_E	87_V	0.703	0.97
329_T	350_W	0.702	0.97
103_H	107_T	0.701	0.97
216_R	228_D	0.701	0.97
225_V	235_E	0.701	0.97
301_R	317_E	0.697	0.97
171_Y	185_V	0.696	0.97
120_E	125_A	0.696	0.97
165_R	172_V	0.696	0.97
208_A	217_T	0.696	0.97
302_E	306_A	0.694	0.97
133_L	141_L	0.693	0.97
174_L	184_N	0.692	0.97
118_R	123_W	0.688	0.96
61_V	67_W	0.687	0.96
470_A	535_V	0.685	0.96
290_L	331_A	0.684	0.96
214_L	220_E	0.684	0.96
95_R	99_S	0.684	0.96
59_P	63_Y	0.683	0.96
418_P	422_I	0.680	0.96
254_D	258_D	0.678	0.96
114_R	125_A	0.677	0.96
77_V	86_I	0.677	0.96
216_R	225_V	0.676	0.96
97_Q	105_T	0.676	0.96
130_L	138_T	0.676	0.96
151_W	154_E	0.674	0.96
67_W	77_V	0.673	0.96
219_Y	224_P	0.672	0.96
138_T	142_P	0.671	0.96
178_T	183_G	0.671	0.96
484_A	517_V	0.670	0.96
113_Y	118_R	0.670	0.96
94_T	99_S	0.667	0.96
100_R	106_D	0.666	0.96
90_P	105_T	0.665	0.96
58_D	64_P	0.664	0.96
299_Q	527_D	0.664	0.96
171_Y	176_A	0.664	0.96
538_S	541_G	0.662	0.96
175_E	179_D	0.662	0.96
119_A	124_A	0.662	0.96
226_R	235_E	0.661	0.96
95_R	104_L	0.661	0.96
132_D	145_C	0.660	0.95
518_V	522_G	0.659	0.95
283_V	352_L	0.657	0.95
169_D	175_E	0.657	0.95
219_Y	233_S	0.657	0.95
76_I	88_D	0.655	0.95
155_Q	163_R	0.655	0.95
94_T	104_L	0.654	0.95
236_P	239_V	0.654	0.95
255_R	262_G	0.653	0.95
234_G	237_L	0.652	0.95
505_F	526_I	0.651	0.95
81_D	88_D	0.651	0.95
147_T	156_W	0.649	0.95
113_Y	119_A	0.648	0.95
217_T	234_G	0.648	0.95
203_E	219_Y	0.647	0.95
174_L	179_D	0.646	0.95
205_W	208_A	0.645	0.95
68_L	77_V	0.645	0.95
68_L	76_I	0.645	0.95
58_D	68_L	0.644	0.95
532_E	559_S	0.643	0.95
450_E	461_L	0.643	0.95
205_W	220_E	0.643	0.95
176_A	185_V	0.642	0.95
74_E	86_I	0.641	0.95
103_H	108_T	0.640	0.95
215_K	228_D	0.640	0.95
121_D	128_D	0.638	0.95
150_E	156_W	0.638	0.95
78_P	89_Q	0.634	0.94
130_L	135_A	0.633	0.94
61_V	68_L	0.633	0.94
118_R	127_F	0.632	0.94
123_W	127_F	0.631	0.94
359_H	549_Q	0.631	0.94
213_P	219_Y	0.630	0.94
60_V	70_L	0.630	0.94
211_V	234_G	0.626	0.94
69_E	76_I	0.625	0.94
454_K	458_I	0.624	0.94
99_S	107_T	0.622	0.94
168_D	173_V	0.618	0.94
90_P	100_R	0.618	0.94
394_I	398_V	0.618	0.94
318_Y	325_V	0.615	0.93
487_L	514_D	0.615	0.93
94_T	108_T	0.614	0.93
204_A	208_A	0.613	0.93
217_T	223_Y	0.611	0.93
513_L	518_V	0.610	0.93
162_F	165_R	0.609	0.93
213_P	221_A	0.609	0.93
90_P	94_T	0.609	0.93
153_R	161_R	0.608	0.93
168_D	174_L	0.608	0.93
206_V	218_L	0.607	0.93
60_V	90_P	0.606	0.93
446_R	450_E	0.604	0.93
204_A	218_L	0.602	0.93
214_L	224_P	0.602	0.93
273_T	300_W	0.601	0.93
66_D	72_D	0.600	0.93
168_D	175_E	0.597	0.92
291_V	300_W	0.597	0.92
349_E	373_Q	0.596	0.92
250_Q	254_D	0.595	0.92
223_Y	229_R	0.593	0.92
113_Y	120_E	0.593	0.92
204_A	224_P	0.592	0.92
136_A	146_P	0.590	0.92
80_P	86_I	0.590	0.92
144_D	150_E	0.590	0.92
172_V	178_T	0.589	0.92
211_V	226_R	0.589	0.92
215_K	229_R	0.589	0.92
203_E	210_Q	0.587	0.92
112_S	118_R	0.587	0.92
178_T	184_N	0.586	0.92
239_V	242_H	0.585	0.92
178_T	186_A	0.583	0.92
154_E	159_A	0.582	0.91
177_A	181_L	0.581	0.91
368_R	371_S	0.581	0.91
177_A	184_N	0.581	0.91
64_P	69_E	0.579	0.91
211_V	217_T	0.577	0.91
157_T	162_F	0.577	0.91
540_L	547_G	0.575	0.91
333_Y	355_Y	0.575	0.91
57_P	64_P	0.572	0.91
75_R	80_P	0.572	0.91
223_Y	231_L	0.571	0.91
322_E	325_V	0.571	0.91
68_L	75_R	0.570	0.91
119_A	126_P	0.570	0.91
173_V	186_A	0.569	0.91
317_E	321_G	0.568	0.90
83_R	90_P	0.567	0.90
76_I	81_D	0.567	0.90
530_D	559_S	0.566	0.90
276_A	279_A	0.566	0.90
154_E	161_R	0.565	0.90
455_E	459_E	0.563	0.90
224_P	231_L	0.562	0.90
118_R	133_L	0.561	0.90
322_E	566_L	0.559	0.90
422_I	427_W	0.558	0.90
69_E	74_E	0.557	0.90
176_A	183_G	0.556	0.89
63_Y	71_T	0.555	0.89
68_L	78_P	0.554	0.89
115_Y	120_E	0.553	0.89
500_R	503_T	0.552	0.89
209_E	226_R	0.551	0.89
412_A	416_A	0.551	0.89
77_V	83_R	0.549	0.89
83_R	89_Q	0.549	0.89
186_A	190_L	0.549	0.89
414_F	421_E	0.544	0.88
89_Q	98_L	0.544	0.88
108_T	121_D	0.542	0.88
109_R	112_S	0.542	0.88
62_W	72_D	0.542	0.88
203_E	214_L	0.541	0.88
81_D	87_V	0.539	0.88
135_A	141_L	0.539	0.88
63_Y	72_D	0.538	0.88
65_R	71_T	0.537	0.88
182_L	193_D	0.537	0.88
117_V	122_V	0.537	0.88
296_L	526_I	0.535	0.88
165_R	173_V	0.534	0.88
315_I	330_I	0.534	0.88
320_G	324_R	0.533	0.87
219_Y	230_D	0.532	0.87
496_T	504_H	0.532	0.87
210_Q	220_E	0.532	0.87
417_E	421_E	0.531	0.87
152_V	156_W	0.531	0.87
482_R	486_R	0.531	0.87
208_A	221_A	0.530	0.87
415_V	419_E	0.528	0.87
170_G	185_V	0.528	0.87
133_L	144_D	0.526	0.87
171_Y	182_L	0.526	0.87
129_S	137_I	0.524	0.87
180_S	186_A	0.524	0.87
317_E	322_E	0.523	0.86
116_E	123_W	0.523	0.86
172_V	188_Q	0.521	0.86
205_W	212_A	0.520	0.86
268_P	382_A	0.520	0.86
95_R	100_R	0.520	0.86
135_A	144_D	0.518	0.86
94_T	106_D	0.518	0.86
87_V	99_S	0.518	0.86
301_R	315_I	0.517	0.86
71_T	76_I	0.515	0.86
228_D	232_E	0.515	0.86
331_A	336_A	0.515	0.86
514_D	519_S	0.514	0.86
64_P	73_R	0.513	0.85
553_R	556_R	0.512	0.85
208_A	214_L	0.510	0.85
140_L	144_D	0.510	0.85
140_L	145_C	0.509	0.85
236_P	241_L	0.509	0.85
113_Y	125_A	0.509	0.85
59_P	64_P	0.509	0.85
244_D	249_Q	0.509	0.85
148_L	153_R	0.507	0.85
134_V	142_P	0.506	0.85
150_E	157_T	0.506	0.85
60_V	71_T	0.506	0.85
190_L	197_A	0.505	0.85
207_A	214_L	0.505	0.85
129_S	139_E	0.504	0.84
165_R	171_Y	0.503	0.84
459_E	463_D	0.500	0.84

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
4pxaA	1	0.645	100	0.453	Contact Map
1z3iX	4	0.6733	100	0.454	Contact Map
3mwyW	2	0.825	100	0.461	Contact Map
4nhoA	1	0.6183	100	0.462	Contact Map
4ljyA	1	0.6367	100	0.471	Contact Map
2db3A	1	0.6333	100	0.473	Contact Map
4d25A	1	0.635	100	0.475	Contact Map
1z63A	1	0.5917	100	0.475	Contact Map
3sqwA	1	0.6033	100	0.481	Contact Map
3i5xA	1	0.6033	100	0.484	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.0144 seconds.