Q9HPY0 - HALSA - GREMLIN Contacts

Home
GREMLIN
- Submit - Monomer
- Submit - Complex
Contacts
Metagenomics
- Contacts
- Structures
Structures
- List
Old Projects
- Complexes (2014)
- PFAM (2013)

Q9HPY0 - Uncharacterized protein

UniProt:	Q9HPY0	Sequences: MTFSIVARDPETDAVGVAVQSKFVAVGSVVPFASADAGAIATQSLANVAYGSDGLDLLRAGHSADEVVAELTNTDDEAPQRQVGVVGQDGSVAAFTGAECVDHASDRQGDHYTAQGNILANRATVDAMADTFEDTDGGLPERLLAALHAGNDAGGDQRGEQGAALYVAKPGGGYDGGNDRWIDVRVDDHDHPIDELERVFHIYDITLLERVAPTEYRELAGDTAESVLAALSGLGFYDGAPGRAFGDAERDALAAFQAVNNFENHDLAALEDALARGWADAAGEGEDRLVNAIWQGISRLDRT	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	303 (263)
Sequences:	242 (190)
Seq/√Len:	11.7

HALSA - Q9HPY0
SULSO - Q97YH1

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
34_S	59_R	5.716	1.00
33_A	168_A	5.364	1.00
94_A	106_D	5.293	1.00
20_Q	151_N	4.098	0.99
87_G	91_S	3.855	0.99
58_L	85_V	3.793	0.99
79_P	98_A	3.198	0.97
116_G	119_L	3.097	0.96
54_G	71_L	3.040	0.96
68_V	72_T	3.038	0.96
112_Y	129_A	2.998	0.95
39_A	86_V	2.960	0.95
151_N	160_E	2.819	0.93
114_A	129_A	2.751	0.93
120_A	124_T	2.738	0.92
195_E	198_R	2.697	0.92
68_V	83_V	2.672	0.91
189_H	195_E	2.671	0.91
148_H	197_E	2.550	0.89
40_I	67_V	2.549	0.89
48_V	177_G	2.527	0.89
160_E	191_H	2.479	0.88
3_F	151_N	2.401	0.86
18_A	143_L	2.389	0.86
94_A	108_Q	2.385	0.86
29_V	46_A	2.326	0.84
58_L	67_V	2.157	0.79
112_Y	133_E	2.113	0.78
106_D	113_T	2.024	0.75
124_T	204_D	2.005	0.74
12_T	15_V	1.922	0.71
151_N	193_I	1.899	0.70
121_N	124_T	1.887	0.69
243_R	246_G	1.855	0.68
189_H	198_R	1.845	0.67
50_Y	72_T	1.838	0.67
56_D	60_A	1.835	0.67
94_A	113_T	1.794	0.65
32_F	51_G	1.778	0.64
258_A	263_E	1.769	0.64
129_A	133_E	1.743	0.63
92_V	108_Q	1.709	0.61
20_Q	193_I	1.709	0.61
33_A	39_A	1.669	0.59
35_A	179_D	1.647	0.58
44_S	80_Q	1.616	0.57
169_K	172_G	1.585	0.55
16_G	143_L	1.558	0.54
91_S	152_D	1.542	0.53
3_F	125_V	1.490	0.50
114_A	132_F	1.479	0.50
64_A	91_S	1.478	0.50
141_E	204_D	1.470	0.49
202_I	206_T	1.456	0.49
260_N	265_H	1.448	0.48
102_D	144_L	1.441	0.48
65_D	69_A	1.434	0.48
17_V	86_V	1.430	0.47
84_G	113_T	1.419	0.47
64_A	87_G	1.415	0.47
191_H	194_D	1.411	0.47
245_F	250_R	1.409	0.46
161_Q	188_D	1.396	0.46
5_I	114_A	1.354	0.44
24_V	207_L	1.343	0.43
109_G	112_Y	1.307	0.41
49_A	53_D	1.305	0.41
59_R	88_Q	1.281	0.40
20_Q	121_N	1.268	0.40
21_S	188_D	1.267	0.40
257_Q	266_D	1.266	0.39
24_V	184_V	1.239	0.38
5_I	139_L	1.238	0.38
53_D	74_T	1.234	0.38
130_D	137_G	1.230	0.38
68_V	85_V	1.219	0.37
14_A	169_K	1.193	0.36
54_G	57_L	1.190	0.36
120_A	151_N	1.186	0.36
62_H	70_E	1.181	0.36
174_Y	261_N	1.167	0.35
132_F	139_L	1.165	0.35
8_R	15_V	1.156	0.34
245_F	249_E	1.156	0.34
12_T	199_V	1.145	0.34
68_V	127_A	1.141	0.34
40_I	65_D	1.137	0.34
39_A	84_G	1.136	0.34
50_Y	83_V	1.129	0.33
109_G	186_V	1.124	0.33
53_D	56_D	1.123	0.33
58_L	71_L	1.121	0.33
26_V	164_A	1.120	0.33
99_E	136_D	1.119	0.33
9_D	51_G	1.118	0.33
20_Q	256_F	1.108	0.32
40_I	85_V	1.106	0.32
147_L	167_V	1.106	0.32
17_V	229_A	1.092	0.32
37_A	85_V	1.085	0.31
236_F	259_V	1.084	0.31
59_R	227_V	1.083	0.31
33_A	166_Y	1.074	0.31
10_P	15_V	1.068	0.31
32_F	150_G	1.058	0.30
54_G	216_Y	1.053	0.30
231_L	235_G	1.051	0.30
47_N	71_L	1.044	0.30
258_A	262_F	1.044	0.30
103_H	125_V	1.042	0.29
255_A	259_V	1.041	0.29
138_G	141_E	1.040	0.29
40_I	200_F	1.035	0.29
17_V	28_S	1.028	0.29
44_S	100_C	1.016	0.28
20_Q	150_G	1.016	0.28
5_I	206_T	1.014	0.28
151_N	191_H	1.013	0.28
35_A	189_H	1.011	0.28
23_F	119_L	1.001	0.28
125_V	174_Y	1.000	0.28
7_A	139_L	0.998	0.28
100_C	104_A	0.991	0.27
104_A	179_D	0.987	0.27
27_G	164_A	0.976	0.27
25_A	248_A	0.974	0.27
213_P	227_V	0.973	0.27
50_Y	71_L	0.970	0.27
7_A	114_A	0.963	0.26
150_G	227_V	0.961	0.26
219_L	227_V	0.960	0.26
127_A	130_D	0.955	0.26
40_I	51_G	0.953	0.26
46_A	100_C	0.947	0.26
84_G	115_Q	0.945	0.26
15_V	39_A	0.938	0.25
176_G	179_D	0.938	0.25
24_V	187_D	0.937	0.25
115_Q	128_M	0.929	0.25
45_L	258_A	0.926	0.25
70_E	110_D	0.917	0.25
7_A	210_R	0.914	0.24
40_I	58_L	0.902	0.24
57_L	90_G	0.902	0.24
18_A	180_R	0.901	0.24
188_D	195_E	0.900	0.24
34_S	37_A	0.896	0.24
5_I	128_M	0.889	0.24
112_Y	186_V	0.886	0.23
25_A	139_L	0.884	0.23
147_L	252_A	0.883	0.23
3_F	116_G	0.881	0.23
174_Y	205_I	0.872	0.23
21_S	30_V	0.868	0.23
29_V	56_D	0.865	0.23
14_A	140_P	0.859	0.23
24_V	185_R	0.858	0.22
20_Q	160_E	0.857	0.22
130_D	190_D	0.853	0.22
84_G	112_Y	0.850	0.22
35_A	146_A	0.848	0.22
67_V	92_V	0.844	0.22
107_R	126_D	0.840	0.22
54_G	67_V	0.840	0.22
14_A	204_D	0.836	0.22
145_A	258_A	0.827	0.21
3_F	166_Y	0.824	0.21
212_A	216_Y	0.823	0.21
30_V	159_G	0.820	0.21
221_G	227_V	0.820	0.21
69_A	134_D	0.813	0.21
259_V	266_D	0.806	0.21
9_D	127_A	0.804	0.21
21_S	159_G	0.803	0.21
23_F	205_I	0.801	0.21
109_G	179_D	0.801	0.21
51_G	180_R	0.800	0.21
188_D	198_R	0.783	0.20
75_D	100_C	0.779	0.20
258_A	266_D	0.778	0.20
9_D	32_F	0.778	0.20
60_A	191_H	0.777	0.20
39_A	113_T	0.774	0.20
9_D	12_T	0.774	0.20
84_G	94_A	0.773	0.20
103_H	143_L	0.772	0.20
11_E	70_E	0.772	0.20
64_A	129_A	0.768	0.20
66_E	189_H	0.765	0.19
14_A	139_L	0.758	0.19
5_I	89_D	0.757	0.19
34_S	56_D	0.757	0.19
74_T	227_V	0.756	0.19
37_A	152_D	0.754	0.19
54_G	91_S	0.752	0.19
32_F	44_S	0.751	0.19
252_A	263_E	0.749	0.19
70_E	73_N	0.745	0.19
184_V	199_V	0.744	0.19
20_Q	124_T	0.738	0.19
67_V	222_D	0.733	0.18
132_F	153_A	0.732	0.18
128_M	139_L	0.732	0.18
52_S	115_Q	0.731	0.18
228_L	232_S	0.728	0.18
124_T	151_N	0.722	0.18
44_S	50_Y	0.721	0.18
116_G	125_V	0.719	0.18
79_P	95_F	0.718	0.18
59_R	150_G	0.716	0.18
20_Q	178_N	0.716	0.18
105_S	125_V	0.716	0.18
110_D	123_A	0.714	0.18
23_F	174_Y	0.714	0.18
112_Y	141_E	0.713	0.18
116_G	121_N	0.713	0.18
25_A	187_D	0.712	0.18
229_A	232_S	0.711	0.18
76_D	251_D	0.710	0.18
45_L	114_A	0.709	0.18
158_R	161_Q	0.709	0.18
122_R	126_D	0.706	0.18
64_A	108_Q	0.706	0.18
86_V	111_H	0.706	0.18
14_A	124_T	0.705	0.18
237_Y	243_R	0.703	0.18
48_V	253_L	0.700	0.17
30_V	41_A	0.699	0.17
249_E	259_V	0.699	0.17
263_E	266_D	0.695	0.17
59_R	67_V	0.693	0.17
40_I	87_G	0.689	0.17
261_N	265_H	0.689	0.17
88_Q	190_D	0.686	0.17
59_R	85_V	0.685	0.17
193_I	259_V	0.684	0.17
173_G	261_N	0.678	0.17
44_S	141_E	0.678	0.17
8_R	181_W	0.674	0.17
64_A	68_V	0.672	0.17
47_N	54_G	0.669	0.17
6_V	168_A	0.664	0.16
105_S	119_L	0.663	0.16
184_V	187_D	0.662	0.16
254_A	266_D	0.662	0.16
228_L	237_Y	0.658	0.16
211_V	215_E	0.657	0.16
137_G	144_L	0.654	0.16
64_A	79_P	0.652	0.16
28_S	48_V	0.652	0.16
79_P	263_E	0.651	0.16
23_F	116_G	0.651	0.16
158_R	188_D	0.650	0.16
169_K	181_W	0.650	0.16
56_D	152_D	0.649	0.16
95_F	230_A	0.649	0.16
103_H	174_Y	0.646	0.16
28_S	142_R	0.645	0.16
138_G	145_A	0.644	0.16
41_A	161_Q	0.644	0.16
37_A	107_R	0.642	0.16
29_V	178_N	0.640	0.16
128_M	149_A	0.640	0.16
144_L	247_D	0.633	0.16
54_G	192_P	0.631	0.16
7_A	227_V	0.630	0.16
112_Y	181_W	0.629	0.16
86_V	113_T	0.629	0.16
44_S	188_D	0.626	0.15
108_Q	147_L	0.624	0.15
250_R	254_A	0.623	0.15
9_D	60_A	0.622	0.15
21_S	156_D	0.622	0.15
204_D	215_E	0.619	0.15
21_S	179_D	0.619	0.15
262_F	265_H	0.618	0.15
15_V	168_A	0.615	0.15
96_T	159_G	0.614	0.15
3_F	115_Q	0.614	0.15
125_V	140_P	0.613	0.15
254_A	259_V	0.613	0.15
175_D	265_H	0.613	0.15
24_V	265_H	0.612	0.15
56_D	140_P	0.610	0.15
57_L	104_A	0.609	0.15
262_F	267_L	0.607	0.15
107_R	130_D	0.606	0.15
65_D	173_G	0.602	0.15
84_G	106_D	0.601	0.15
8_R	12_T	0.601	0.15
205_I	260_N	0.600	0.15
44_S	214_T	0.600	0.15
161_Q	195_E	0.600	0.15
14_A	268_A	0.600	0.15
63_S	251_D	0.598	0.15
16_G	31_P	0.596	0.15
68_V	227_V	0.596	0.15
172_G	180_R	0.595	0.15
89_D	136_D	0.594	0.15
114_A	257_Q	0.593	0.15
22_K	116_G	0.592	0.15
201_H	251_D	0.592	0.15
66_E	69_A	0.592	0.15
12_T	56_D	0.591	0.15
72_T	95_F	0.590	0.15
23_F	46_A	0.590	0.15
40_I	54_G	0.588	0.15
103_H	205_I	0.587	0.14
50_Y	256_F	0.587	0.14
25_A	92_V	0.586	0.14
19_V	115_Q	0.580	0.14
78_A	118_I	0.580	0.14
6_V	86_V	0.580	0.14
11_E	145_A	0.578	0.14
57_L	71_L	0.577	0.14
214_T	230_A	0.575	0.14
261_N	264_N	0.573	0.14
34_S	141_E	0.570	0.14
138_G	229_A	0.569	0.14
6_V	144_L	0.568	0.14
111_H	124_T	0.567	0.14
116_G	261_N	0.567	0.14
65_D	232_S	0.566	0.14
84_G	236_F	0.563	0.14
139_L	153_A	0.562	0.14
21_S	158_R	0.562	0.14
251_D	266_D	0.560	0.14
165_L	264_N	0.558	0.14
76_D	215_E	0.558	0.14
5_I	225_E	0.555	0.14
124_T	200_F	0.554	0.14
51_G	62_H	0.551	0.14
18_A	139_L	0.550	0.14
112_Y	123_A	0.549	0.14
50_Y	220_A	0.548	0.14
13_D	36_D	0.548	0.14
100_C	106_D	0.548	0.14
18_A	193_I	0.548	0.14
127_A	240_A	0.547	0.14
184_V	206_T	0.545	0.13
72_T	197_E	0.543	0.13
9_D	21_S	0.543	0.13
90_G	104_A	0.542	0.13
22_K	174_Y	0.542	0.13
76_D	218_E	0.541	0.13
84_G	157_Q	0.541	0.13
29_V	67_V	0.541	0.13
47_N	179_D	0.540	0.13
245_F	266_D	0.538	0.13
230_A	240_A	0.538	0.13
121_N	152_D	0.537	0.13
5_I	18_A	0.536	0.13
29_V	194_D	0.536	0.13
18_A	124_T	0.536	0.13
227_V	231_L	0.536	0.13
246_G	249_E	0.535	0.13
44_S	193_I	0.533	0.13
160_E	200_F	0.533	0.13
86_V	213_P	0.533	0.13
25_A	185_R	0.533	0.13
22_K	236_F	0.531	0.13
120_A	123_A	0.529	0.13
32_F	64_A	0.529	0.13
126_D	133_E	0.529	0.13
118_I	166_Y	0.528	0.13
253_L	256_F	0.528	0.13
129_A	186_V	0.527	0.13
152_D	223_T	0.527	0.13
181_W	228_L	0.527	0.13
131_T	194_D	0.524	0.13
247_D	268_A	0.523	0.13
200_F	266_D	0.523	0.13
106_D	174_Y	0.521	0.13
114_A	128_M	0.516	0.13
25_A	79_P	0.514	0.13
74_T	140_P	0.514	0.13
8_R	111_H	0.514	0.13
18_A	103_H	0.513	0.13
18_A	174_Y	0.513	0.13
67_V	215_E	0.513	0.13
31_P	164_A	0.511	0.13
74_T	83_V	0.511	0.13
42_T	75_D	0.511	0.13
40_I	89_D	0.507	0.13
36_D	59_R	0.507	0.13
140_P	160_E	0.507	0.13
58_L	121_N	0.506	0.13
114_A	256_F	0.506	0.13
22_K	119_L	0.505	0.13
258_A	267_L	0.504	0.13
87_G	193_I	0.503	0.13
108_Q	191_H	0.503	0.13
28_S	45_L	0.502	0.13
16_G	231_L	0.500	0.12

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
2imhA	2	0.7294	100	0.383	Contact Map
4fetB	1	0.033	69	0.966	Contact Map
3bkhA	1	0.2871	66.4	0.967	Contact Map
4lpqA	1	0.297	62.6	0.968	Contact Map
4o0cA	2	0.4092	59.9	0.968	Contact Map
4nsoA	1	0.0297	57.6	0.969	Contact Map
4pv2B	2	0.3828	55.2	0.969	Contact Map
3c17A	2	0.3993	43.7	0.971	Contact Map
2gezB	2	0.3828	39.9	0.972	Contact Map
4g54A	1	0.5446	34.6	0.973	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.0094 seconds.