HISX - HALSA - GREMLIN Contacts

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HISX - Histidinol dehydrogenase

UniProt:	Q9HPW5	Sequences: MEYEAVADLAPDRRVALFERDAGVDAVRSDVAEILDRVESEGDVALRALASEFDDVEVGNLDVTDEMERAADAVPDDVYDAIEDAAANIRAFHEAQLPDDWRESFAAGRELGRRFRPVRRVGVYAPGGTAAYPSSVLMGVIPAVVAGVEQVAVATPPAETINPVTLAAAHAAGADRVYQVGGAQAIGAFAYGTETVDTVQTVVGPGNKWVTAAKAEVRGDVEIDFLAGPSELLVVADETAEPAFVAADLLAQAEHDPNASVVAVTDDEATAAAITDAVAARLDDRERADTIRAALDNEASGVFVARSMSEAVMFAEEYAAEHLSIQASDDEALLDRIDSAGSVFLGGYAPVAAGDYAAGTNHVLPTNGTARVTGGLSVDTFLRSTTVQRLDREGLAALRETVTTLADAEGLEGHAASVDARFEDE	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	425 (410)
Sequences:	3821 (2157)
Seq/√Len:	106.5

ECOLI - HISX
BACSU - HISX
HALSA - HISX
SULSO - HISX

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
37_R	41_E	4.148	1.00
51_S	57_E	4.069	1.00
41_E	48_A	3.578	1.00
62_D	176_R	3.247	1.00
35_L	187_G	3.152	1.00
120_R	150_Q	3.139	1.00
154_A	189_F	3.068	1.00
129_T	257_P	3.063	1.00
288_A	292_R	2.949	1.00
243_A	277_A	2.932	1.00
329_D	332_A	2.801	1.00
235_V	315_A	2.771	1.00
89_I	137_L	2.757	1.00
90_R	94_E	2.721	1.00
123_V	140_V	2.690	1.00
331_E	389_R	2.547	1.00
84_D	401_T	2.531	1.00
150_Q	176_R	2.527	1.00
73_A	163_P	2.494	1.00
306_R	310_E	2.493	1.00
309_S	336_R	2.490	1.00
268_E	272_A	2.485	1.00
37_R	49_L	2.454	1.00
277_A	280_A	2.361	1.00
407_D	419_D	2.322	1.00
71_A	170_H	2.311	1.00
119_R	338_D	2.283	1.00
144_V	175_D	2.259	1.00
83_E	171_A	2.149	1.00
305_A	311_A	2.132	1.00
67_M	177_V	2.117	1.00
271_A	304_V	2.082	1.00
271_A	302_V	2.077	1.00
48_A	52_E	2.058	1.00
292_R	296_D	2.041	1.00
86_A	90_R	2.041	1.00
407_D	412_E	2.032	1.00
238_E	267_D	2.031	1.00
399_R	422_F	2.030	1.00
43_D	193_T	2.015	1.00
403_T	419_D	2.003	1.00
55_D	159_E	1.991	1.00
233_L	315_A	1.989	1.00
212_A	216_E	1.956	1.00
37_R	48_A	1.943	1.00
41_E	44_V	1.943	1.00
312_V	337_I	1.941	1.00
256_D	259_A	1.934	1.00
140_V	174_A	1.932	1.00
149_E	338_D	1.928	1.00
200_Q	371_R	1.926	1.00
86_A	141_I	1.924	1.00
30_D	209_W	1.910	1.00
33_E	37_R	1.907	1.00
36_D	40_S	1.904	1.00
275_T	302_V	1.899	1.00
235_V	311_A	1.865	1.00
232_L	251_A	1.856	1.00
68_E	72_D	1.849	1.00
68_E	170_H	1.817	1.00
239_T	328_S	1.784	1.00
269_A	273_A	1.761	1.00
119_R	339_S	1.759	1.00
79_Y	83_E	1.758	1.00
282_L	291_I	1.755	1.00
265_T	271_A	1.740	1.00
286_E	412_E	1.724	1.00
416_A	419_D	1.724	1.00
119_R	149_E	1.711	1.00
90_R	144_V	1.699	1.00
62_D	178_Y	1.692	1.00
352_A	417_S	1.687	1.00
312_V	333_L	1.684	1.00
392_R	396_A	1.676	1.00
353_A	402_V	1.650	1.00
32_A	216_E	1.623	1.00
191_Y	220_D	1.619	1.00
118_V	201_T	1.600	1.00
66_E	179_Q	1.600	1.00
238_E	266_D	1.595	1.00
307_S	310_E	1.551	1.00
325_I	337_I	1.534	1.00
330_D	345_L	1.532	1.00
153_V	169_A	1.528	1.00
47_R	61_L	1.514	1.00
247_A	281_R	1.502	1.00
79_Y	167_A	1.495	1.00
69_R	73_A	1.494	1.00
116_R	385_T	1.492	1.00
266_D	305_A	1.488	1.00
102_R	110_E	1.478	1.00
78_V	408_A	1.459	1.00
211_T	226_L	1.456	1.00
71_A	167_A	1.449	1.00
43_D	195_T	1.424	1.00
178_Y	197_D	1.421	1.00
277_A	281_R	1.417	1.00
76_D	80_D	1.414	1.00
263_A	274_I	1.412	1.00
403_T	407_D	1.404	1.00
180_V	196_V	1.402	1.00
81_A	405_L	1.398	1.00
86_A	137_L	1.390	1.00
155_T	161_I	1.386	1.00
137_L	141_I	1.381	1.00
122_G	189_F	1.381	1.00
327_A	333_L	1.376	1.00
238_E	328_S	1.373	1.00
65_D	69_R	1.365	1.00
98_P	379_D	1.348	1.00
285_R	291_I	1.347	1.00
358_A	388_Q	1.337	0.99
243_A	280_A	1.337	0.99
121_V	201_T	1.326	0.99
81_A	404_T	1.316	0.99
136_V	153_V	1.309	0.99
379_D	384_S	1.304	0.99
403_T	415_A	1.299	0.99
154_A	185_A	1.295	0.99
152_A	176_R	1.294	0.99
348_Y	392_R	1.293	0.99
273_A	276_D	1.290	0.99
293_A	296_D	1.288	0.99
28_R	32_A	1.280	0.99
82_I	171_A	1.280	0.99
167_A	170_H	1.279	0.99
70_A	166_L	1.271	0.99
168_A	172_A	1.266	0.99
343_V	385_T	1.266	0.99
190_A	217_V	1.265	0.99
257_P	293_A	1.264	0.99
326_Q	347_G	1.261	0.99
407_D	415_A	1.260	0.99
339_S	383_R	1.258	0.99
279_A	292_R	1.251	0.99
233_L	264_V	1.249	0.99
38_V	187_G	1.248	0.99
152_A	189_F	1.247	0.99
270_T	274_I	1.233	0.99
86_A	171_A	1.231	0.99
151_V	175_D	1.219	0.99
35_L	220_D	1.214	0.99
28_R	216_E	1.211	0.99
74_V	79_Y	1.211	0.99
191_Y	217_V	1.207	0.99
239_T	347_G	1.202	0.99
69_R	160_T	1.201	0.99
135_S	139_G	1.200	0.99
395_L	418_V	1.193	0.99
235_V	264_V	1.192	0.99
78_V	164_V	1.191	0.99
241_E	244_F	1.187	0.99
129_T	287_R	1.185	0.99
415_A	419_D	1.184	0.99
208_K	212_A	1.178	0.99
98_P	382_L	1.170	0.99
63_V	166_L	1.162	0.99
283_D	288_A	1.160	0.99
32_A	36_D	1.144	0.98
293_A	297_N	1.137	0.98
315_A	320_A	1.134	0.98
63_V	179_Q	1.133	0.98
201_T	380_T	1.132	0.98
264_V	314_F	1.126	0.98
281_R	416_A	1.121	0.98
44_V	194_E	1.119	0.98
235_V	325_I	1.119	0.98
154_A	180_V	1.116	0.98
343_V	387_V	1.116	0.98
46_L	180_V	1.115	0.98
217_V	221_V	1.103	0.98
245_V	274_I	1.098	0.98
139_G	363_V	1.088	0.98
35_L	217_V	1.084	0.98
264_V	305_A	1.079	0.98
357_A	402_V	1.077	0.98
240_A	245_V	1.076	0.98
27_V	212_A	1.069	0.97
243_A	420_A	1.068	0.97
327_A	330_D	1.066	0.97
116_R	383_R	1.065	0.97
29_S	33_E	1.064	0.97
34_I	183_A	1.054	0.97
82_I	405_L	1.054	0.97
110_E	389_R	1.053	0.97
242_P	273_A	1.051	0.97
357_A	401_T	1.047	0.97
319_A	370_A	1.047	0.97
265_T	302_V	1.044	0.97
123_V	151_V	1.038	0.97
50_A	184_Q	1.032	0.97
236_A	270_T	1.031	0.97
268_E	304_V	1.029	0.97
250_L	291_I	1.028	0.97
49_L	53_F	1.027	0.97
71_A	79_Y	1.026	0.97
118_V	121_V	1.025	0.97
144_V	172_A	1.022	0.97
98_P	115_F	1.015	0.97
377_S	384_S	1.007	0.96
250_L	413_G	1.005	0.96
369_T	372_V	1.003	0.96
305_A	314_F	1.000	0.96
265_T	304_V	0.998	0.96
94_E	145_V	0.997	0.96
235_V	312_V	0.996	0.96
234_V	249_L	0.985	0.96
353_A	390_L	0.970	0.95
61_L	180_V	0.967	0.95
232_L	324_S	0.963	0.95
276_D	280_A	0.963	0.95
35_L	191_Y	0.963	0.95
118_V	222_E	0.962	0.95
80_D	83_E	0.960	0.95
251_A	352_A	0.959	0.95
241_E	347_G	0.959	0.95
63_V	70_A	0.958	0.95
104_S	107_A	0.957	0.95
249_L	263_A	0.955	0.95
334_L	345_L	0.953	0.95
264_V	315_A	0.951	0.95
31_V	212_A	0.949	0.95
135_S	363_V	0.949	0.95
39_E	220_D	0.942	0.95
35_L	39_E	0.937	0.95
363_V	376_L	0.936	0.95
280_A	284_D	0.936	0.95
139_G	203_V	0.935	0.95
325_I	345_L	0.933	0.94
350_P	417_S	0.933	0.94
68_E	71_A	0.932	0.94
308_M	333_L	0.930	0.94
82_I	168_A	0.929	0.94
34_I	38_V	0.929	0.94
97_L	382_L	0.928	0.94
28_R	212_A	0.925	0.94
283_D	292_R	0.924	0.94
236_A	240_A	0.923	0.94
95_A	103_E	0.920	0.94
87_A	90_R	0.917	0.94
266_D	311_A	0.916	0.94
416_A	420_A	0.911	0.94
75_P	78_V	0.911	0.94
390_L	398_L	0.909	0.94
395_L	399_R	0.907	0.94
30_D	33_E	0.904	0.93
44_V	48_A	0.901	0.93
50_A	58_V	0.899	0.93
275_T	279_A	0.899	0.93
245_V	270_T	0.898	0.93
37_R	52_E	0.897	0.93
247_A	420_A	0.893	0.93
402_V	418_V	0.892	0.93
105_F	109_R	0.888	0.93
140_V	172_A	0.885	0.93
41_E	52_E	0.877	0.92
67_M	71_A	0.875	0.92
38_V	183_A	0.872	0.92
353_A	398_L	0.868	0.92
334_L	387_V	0.861	0.92
235_V	308_M	0.861	0.92
83_E	167_A	0.861	0.92
212_A	215_A	0.861	0.92
308_M	311_A	0.860	0.92
188_A	196_V	0.859	0.92
265_T	270_T	0.858	0.92
244_F	347_G	0.857	0.92
81_A	401_T	0.857	0.92
283_D	286_E	0.856	0.91
67_M	170_H	0.853	0.91
77_D	404_T	0.852	0.91
78_V	404_T	0.851	0.91
119_R	200_Q	0.850	0.91
39_E	191_Y	0.848	0.91
90_R	141_I	0.847	0.91
125_A	153_V	0.846	0.91
25_D	29_S	0.846	0.91
46_L	183_A	0.844	0.91
101_W	113_R	0.843	0.91
310_E	313_M	0.843	0.91
91_A	95_A	0.842	0.91
342_S	388_Q	0.835	0.90
289_D	292_R	0.834	0.90
281_R	420_A	0.832	0.90
342_S	386_T	0.831	0.90
375_G	386_T	0.831	0.90
266_D	308_M	0.828	0.90
87_A	91_A	0.827	0.90
150_Q	178_Y	0.825	0.90
337_I	343_V	0.824	0.90
25_D	32_A	0.824	0.90
34_I	49_L	0.823	0.90
176_R	197_D	0.823	0.90
101_W	112_G	0.822	0.90
107_A	397_A	0.818	0.90
334_L	343_V	0.818	0.90
279_A	283_D	0.817	0.89
152_A	197_D	0.815	0.89
46_L	188_A	0.815	0.89
46_L	193_T	0.814	0.89
243_A	423_E	0.813	0.89
242_P	274_I	0.813	0.89
379_D	382_L	0.810	0.89
272_A	275_T	0.803	0.89
313_M	316_E	0.803	0.89
200_Q	339_S	0.799	0.88
136_V	168_A	0.799	0.88
66_E	160_T	0.797	0.88
342_S	387_V	0.796	0.88
249_L	278_V	0.795	0.88
123_V	139_G	0.791	0.88
243_A	281_R	0.790	0.88
93_H	96_Q	0.786	0.88
88_N	357_A	0.785	0.88
133_P	405_L	0.785	0.88
92_F	360_T	0.783	0.87
316_E	336_R	0.782	0.87
97_L	145_V	0.781	0.87
41_E	45_A	0.779	0.87
234_V	245_V	0.778	0.87
85_A	89_I	0.778	0.87
312_V	336_R	0.778	0.87
350_P	395_L	0.776	0.87
396_A	422_F	0.776	0.87
47_R	51_S	0.776	0.87
96_Q	361_N	0.774	0.87
393_E	396_A	0.770	0.86
91_A	94_E	0.770	0.86
56_V	157_P	0.768	0.86
264_V	311_A	0.767	0.86
64_T	179_Q	0.766	0.86
157_P	161_I	0.764	0.86
152_A	178_Y	0.761	0.86
240_A	270_T	0.758	0.86
178_Y	196_V	0.757	0.86
139_G	376_L	0.756	0.85
328_S	347_G	0.756	0.85
26_A	29_S	0.756	0.85
85_A	357_A	0.755	0.85
188_A	193_T	0.754	0.85
202_V	217_V	0.754	0.85
33_E	36_D	0.754	0.85
35_L	216_E	0.753	0.85
71_A	171_A	0.753	0.85
27_V	208_K	0.752	0.85
377_S	382_L	0.752	0.85
94_E	97_L	0.752	0.85
233_L	318_Y	0.751	0.85
406_A	415_A	0.751	0.85
131_A	410_G	0.751	0.85
150_Q	197_D	0.750	0.85
222_E	372_V	0.749	0.85
51_S	56_V	0.747	0.85
136_V	174_A	0.745	0.85
198_T	368_G	0.744	0.85
33_E	52_E	0.742	0.84
412_E	416_A	0.742	0.84
353_A	395_L	0.742	0.84
287_R	290_T	0.741	0.84
47_R	58_V	0.741	0.84
30_D	52_E	0.740	0.84
43_D	194_E	0.739	0.84
342_S	358_A	0.739	0.84
91_A	103_E	0.739	0.84
404_T	408_A	0.739	0.84
232_L	261_V	0.736	0.84
251_A	417_S	0.734	0.84
49_L	184_Q	0.734	0.84
47_R	59_G	0.732	0.84
250_L	282_L	0.732	0.84
167_A	171_A	0.732	0.84
123_V	203_V	0.730	0.83
276_D	279_A	0.730	0.83
312_V	327_A	0.728	0.83
360_T	388_Q	0.726	0.83
357_A	398_L	0.726	0.83
44_V	47_R	0.725	0.83
86_A	172_A	0.725	0.83
376_L	380_T	0.724	0.83
46_L	50_A	0.722	0.83
390_L	394_G	0.721	0.83
272_A	276_D	0.719	0.83
193_T	196_V	0.718	0.82
144_V	174_A	0.718	0.82
244_F	326_Q	0.715	0.82
30_D	49_L	0.715	0.82
139_G	361_N	0.714	0.82
113_R	377_S	0.714	0.82
374_G	384_S	0.713	0.82
202_V	221_V	0.709	0.82
285_R	413_G	0.708	0.82
269_A	272_A	0.707	0.81
332_A	335_D	0.707	0.81
115_F	382_L	0.705	0.81
62_D	150_Q	0.704	0.81
208_K	258_N	0.702	0.81
137_L	168_A	0.701	0.81
399_R	403_T	0.700	0.81
187_G	217_V	0.700	0.81
116_R	338_D	0.696	0.80
278_V	295_L	0.695	0.80
222_E	373_T	0.694	0.80
41_E	49_L	0.693	0.80
238_E	269_A	0.692	0.80
83_E	87_A	0.691	0.80
407_D	416_A	0.690	0.80
289_D	293_A	0.690	0.80
51_S	58_V	0.689	0.80
27_V	31_V	0.688	0.80
170_H	177_V	0.685	0.79
26_A	30_D	0.684	0.79
240_A	347_G	0.683	0.79
217_V	220_D	0.683	0.79
63_V	66_E	0.682	0.79
37_R	40_S	0.681	0.79
130_A	411_L	0.681	0.79
395_L	402_V	0.681	0.79
349_A	390_L	0.680	0.79
242_P	270_T	0.679	0.79
285_R	416_A	0.679	0.79
87_A	94_E	0.678	0.79
122_G	154_A	0.678	0.79
77_D	400_E	0.678	0.79
400_E	404_T	0.677	0.79
102_R	331_E	0.676	0.78
74_V	167_A	0.676	0.78
84_D	357_A	0.675	0.78
47_R	57_E	0.674	0.78
66_E	69_R	0.674	0.78
344_F	354_G	0.669	0.78
215_A	219_G	0.666	0.77
84_D	87_A	0.665	0.77
270_T	273_A	0.665	0.77
47_R	60_N	0.660	0.77
311_A	315_A	0.659	0.77
46_L	49_L	0.658	0.77
308_M	312_V	0.658	0.77
330_D	334_L	0.656	0.76
308_M	327_A	0.656	0.76
97_L	100_D	0.655	0.76
261_V	300_S	0.655	0.76
88_N	402_V	0.650	0.76
69_R	72_D	0.649	0.76
29_S	32_A	0.649	0.76
308_M	315_A	0.647	0.75
131_A	162_N	0.646	0.75
251_A	413_G	0.645	0.75
316_E	334_L	0.645	0.75
71_A	166_L	0.644	0.75
250_L	285_R	0.644	0.75
71_A	83_E	0.644	0.75
120_R	200_Q	0.642	0.75
316_E	338_D	0.641	0.75
50_A	55_D	0.635	0.74
73_A	160_T	0.635	0.74
320_A	323_L	0.635	0.74
180_V	188_A	0.633	0.74
164_V	408_A	0.630	0.73
118_V	148_V	0.628	0.73
45_A	49_L	0.626	0.73
235_V	327_A	0.626	0.73
340_A	343_V	0.625	0.73
275_T	278_V	0.624	0.73
123_V	174_A	0.624	0.73
46_L	61_L	0.622	0.73
178_Y	195_T	0.621	0.72
227_A	361_N	0.620	0.72
100_D	115_F	0.620	0.72
62_D	152_A	0.618	0.72
282_L	292_R	0.618	0.72
114_R	335_D	0.618	0.72
136_V	172_A	0.615	0.72
226_L	373_T	0.615	0.72
266_D	307_S	0.614	0.72
86_A	89_I	0.614	0.72
285_R	412_E	0.613	0.71
219_G	372_V	0.610	0.71
412_E	419_D	0.609	0.71
65_D	68_E	0.609	0.71
201_T	222_E	0.608	0.71
198_T	220_D	0.608	0.71
280_A	283_D	0.607	0.71
315_A	337_I	0.607	0.71
291_I	295_L	0.606	0.71
199_V	221_V	0.605	0.70
23_G	26_A	0.604	0.70
240_A	326_Q	0.603	0.70
349_A	388_Q	0.601	0.70
92_F	386_T	0.601	0.70
312_V	343_V	0.600	0.70
123_V	153_V	0.600	0.70
281_R	285_R	0.599	0.70
85_A	405_L	0.598	0.70
284_D	416_A	0.598	0.70
244_F	348_Y	0.598	0.70
102_R	387_V	0.597	0.69
90_R	145_V	0.596	0.69
82_I	164_V	0.594	0.69
80_D	84_D	0.594	0.69
139_G	153_V	0.592	0.69
96_Q	113_R	0.592	0.69
129_T	225_F	0.590	0.69
130_A	287_R	0.589	0.68
120_R	199_V	0.584	0.68
287_R	410_G	0.584	0.68
120_R	152_A	0.583	0.68
330_D	389_R	0.583	0.68
67_M	167_A	0.580	0.67
82_I	167_A	0.579	0.67
203_V	363_V	0.574	0.66
110_E	391_D	0.574	0.66
166_L	381_F	0.573	0.66
355_D	362_H	0.573	0.66
253_A	261_V	0.572	0.66
16_A	19_E	0.571	0.66
313_M	317_E	0.571	0.66
35_L	46_L	0.571	0.66
245_V	326_Q	0.570	0.66
34_I	53_F	0.569	0.66
278_V	283_D	0.568	0.66
16_A	301_G	0.567	0.66
63_V	177_V	0.567	0.66
252_Q	355_D	0.566	0.65
153_V	174_A	0.565	0.65
102_R	112_G	0.563	0.65
46_L	196_V	0.562	0.65
344_F	351_V	0.561	0.65
271_A	275_T	0.560	0.65
233_L	314_F	0.560	0.65
244_F	420_A	0.557	0.64
342_S	360_T	0.557	0.64
249_L	261_V	0.556	0.64
294_A	300_S	0.556	0.64
395_L	422_F	0.556	0.64
23_G	27_V	0.554	0.64
309_S	313_M	0.554	0.64
286_E	291_I	0.554	0.64
250_L	295_L	0.553	0.64
317_E	371_R	0.552	0.63
38_V	56_V	0.551	0.63
88_N	105_F	0.551	0.63
67_M	79_Y	0.550	0.63
30_D	38_V	0.550	0.63
43_D	188_A	0.549	0.63
324_S	361_N	0.549	0.63
132_Y	411_L	0.548	0.63
80_D	401_T	0.547	0.63
35_L	190_A	0.547	0.63
121_V	203_V	0.546	0.63
391_D	394_G	0.546	0.63
77_D	81_A	0.544	0.62
337_I	385_T	0.544	0.62
100_D	114_R	0.544	0.62
114_R	385_T	0.544	0.62
116_R	387_V	0.543	0.62
17_L	20_R	0.543	0.62
70_A	167_A	0.541	0.62
157_P	180_V	0.541	0.62
74_V	171_A	0.539	0.62
166_L	177_V	0.539	0.62
203_V	376_L	0.539	0.62
38_V	154_A	0.538	0.61
398_L	401_T	0.537	0.61
154_A	157_P	0.536	0.61
237_D	240_A	0.536	0.61
215_A	218_R	0.536	0.61
118_V	380_T	0.535	0.61
260_S	318_Y	0.534	0.61
286_E	407_D	0.534	0.61
394_G	398_L	0.533	0.61
63_V	157_P	0.533	0.61
266_D	270_T	0.533	0.61
265_T	274_I	0.533	0.61
403_T	422_F	0.532	0.61
267_D	270_T	0.531	0.60
229_P	258_N	0.531	0.60
101_W	114_R	0.530	0.60
127_G	130_A	0.530	0.60
47_R	195_T	0.529	0.60
150_Q	175_D	0.528	0.60
352_A	418_V	0.528	0.60
31_V	216_E	0.526	0.60
155_T	158_A	0.526	0.60
115_F	384_S	0.526	0.60
79_Y	171_A	0.525	0.60
111_L	342_S	0.525	0.60
79_Y	170_H	0.525	0.60
114_R	387_V	0.523	0.59
48_A	51_S	0.523	0.59
119_R	316_E	0.522	0.59
277_A	418_V	0.518	0.59
112_G	331_E	0.518	0.59
395_L	420_A	0.517	0.58
95_A	101_W	0.517	0.58
113_R	384_S	0.517	0.58
238_E	273_A	0.516	0.58
215_A	372_V	0.516	0.58
67_M	166_L	0.515	0.58
168_A	405_L	0.515	0.58
137_L	172_A	0.513	0.58
225_F	342_S	0.511	0.58
78_V	405_L	0.509	0.57
127_G	132_Y	0.509	0.57
25_D	36_D	0.507	0.57
218_R	373_T	0.506	0.57
350_P	399_R	0.506	0.57
93_H	145_V	0.506	0.57
40_S	276_D	0.504	0.57
93_H	361_N	0.504	0.57
74_V	78_V	0.503	0.56
154_A	178_Y	0.503	0.56
303_F	314_F	0.503	0.56
211_T	227_A	0.502	0.56
350_P	418_V	0.501	0.56
398_L	402_V	0.500	0.56

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
4g09A	2	0.9859	100	0.021	Contact Map
1kaeA	2	0.9906	100	0.032	Contact Map
4gicA	2	0.8729	100	0.053	Contact Map
3my7A	2	0.7906	97.9	0.948	Contact Map
4itaA	2	0.8188	97.8	0.949	Contact Map
4ghkA	3	0.8141	97.6	0.952	Contact Map
1o20A	3	0.8376	97.6	0.952	Contact Map
3lnsA	2	0.8306	97.5	0.952	Contact Map
1euhA	4	0.8424	97.5	0.952	Contact Map
3vz0A	2	0.8188	97.5	0.953	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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