Q9HPV0 - HALSA - GREMLIN Contacts

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Q9HPV0 - Cell division cycle protein

UniProt:	Q9HPV0	Sequences: MTRVRVTLRDAADRTADAPAVGPGQLSFTAETRQQIGVAEGDAVTVTGSEDTVATVGPDTTAIAASSGLAGADVLRNVGPTDTVTVAPADPSPAAELTVAPATSSTLEGDADALARALAGRHLVADDRIAVPLFSGTVVVTLDVEDTTPGGPVTVTADTAITLTGHAADSGHADAEHATPADTRVGGLDDERGALRRLVVAPLVADSYAAIGVRPPAGVLVHGPAGTGKTTLVRAVAAAADLAVESVAPEDAGDRDALAAVLDAARDAEPGCVVFVESLAAAAPDPTADGASGRGSPSALGWLLDRVRGHDTVVVVGETTDPDAVDPALRRGGRFDAEVRVGVPDPAARRAILDVHTDGVRLADAVSLDAVADRTHGYTGADLTAVLVDAATRAAGSAAGPPVIRQRDLEAALDAVGPSTLRDASVQTPTTTYQDIGGLDRAKREVVRTVEWPQRYPALFERLDAAAPTGVLLHGPPGTGKTMLAKAVAASTDANFLSVDGPELMNRYVGESERGVRDLFERARRLAPAVVFLDEVDSLAPARHDTDTGASERVVSQLLTELDGLSPRGSVAVLAATNRRESVDPALLRPGRIETQVAVPIPDQDARAAIFEVQLDGVATGRIDTTALAAATTGYTGSDIAGVVREGALLAMEDHLRETEFDATDASGLVVTQRHLRRAIETTAPSVDGAG	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	691 (531)
Sequences:	1281 (789)
Seq/√Len:	34.2

HALSA - Q9HPV0 Q9HPU1 Q9HHW2 CDCH
SULSO - Q97ZZ9 Q980U9 Q97V06

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
185_V	243_A	4.885	1.00
349_R	372_A	4.689	1.00
409_L	412_A	4.267	1.00
346_P	372_A	4.195	1.00
188_L	192_R	3.843	1.00
410_E	417_G	3.823	1.00
413_L	419_S	3.728	1.00
412_A	417_G	3.666	1.00
410_E	416_V	3.588	1.00
409_L	413_L	3.585	1.00
412_A	419_S	3.584	1.00
409_L	416_V	3.487	1.00
409_L	419_S	3.470	1.00
420_T	424_A	3.465	1.00
409_L	417_G	3.371	1.00
413_L	416_V	3.226	1.00
183_T	245_E	3.145	1.00
413_L	417_G	3.140	1.00
412_A	416_V	3.131	1.00
485_A	574_L	3.051	1.00
371_V	375_T	3.050	1.00
410_E	418_P	3.042	1.00
371_V	374_R	3.037	1.00
575_A	593_I	2.897	1.00
409_L	418_P	2.871	1.00
620_T	623_I	2.846	1.00
413_L	418_P	2.745	1.00
368_L	371_V	2.712	1.00
404_I	409_L	2.636	1.00
412_A	418_P	2.591	1.00
414_D	419_S	2.558	1.00
416_V	419_S	2.548	1.00
409_L	414_D	2.544	1.00
428_T	433_Y	2.531	1.00
429_P	433_Y	2.521	1.00
351_A	354_D	2.515	1.00
425_S	429_P	2.505	1.00
425_S	428_T	2.440	1.00
426_V	434_Q	2.420	1.00
621_G	624_D	2.417	1.00
431_T	434_Q	2.396	0.99
428_T	432_T	2.358	0.99
603_D	606_A	2.317	0.99
410_E	413_L	2.289	0.99
427_Q	430_T	2.268	0.99
414_D	417_G	2.256	0.99
472_L	593_I	2.217	0.99
420_T	423_D	2.214	0.99
403_V	409_L	2.194	0.99
210_A	339_V	2.166	0.99
141_T	144_V	2.152	0.99
368_L	372_A	2.152	0.99
410_E	419_S	2.149	0.99
350_R	368_L	2.146	0.99
372_A	375_T	2.136	0.99
412_A	415_A	2.100	0.99
579_R	582_S	2.083	0.99
495_N	526_L	2.058	0.98
403_V	410_E	2.023	0.98
345_D	348_A	2.021	0.98
404_I	413_L	2.003	0.98
425_S	432_T	1.998	0.98
473_L	574_L	1.995	0.98
127_D	130_A	1.966	0.98
426_V	429_P	1.963	0.98
414_D	418_P	1.930	0.98
368_L	374_R	1.902	0.97
405_R	417_G	1.880	0.97
428_T	491_S	1.873	0.97
429_P	432_T	1.860	0.97
369_D	372_A	1.855	0.97
474_H	577_T	1.853	0.97
409_L	415_A	1.846	0.97
144_V	148_T	1.833	0.97
407_R	410_E	1.820	0.97
425_S	433_Y	1.808	0.96
445_E	597_V	1.800	0.96
263_D	267_D	1.789	0.96
317_G	320_T	1.748	0.96
368_L	375_T	1.747	0.96
404_I	417_G	1.740	0.96
404_I	418_P	1.738	0.95
184_R	189_D	1.737	0.95
348_A	351_A	1.725	0.95
426_V	430_T	1.707	0.95
74_V	79_G	1.706	0.95
262_L	307_V	1.692	0.95
443_K	484_L	1.687	0.95
472_L	536_V	1.667	0.94
370_A	375_T	1.660	0.94
155_V	165_G	1.652	0.94
415_A	419_S	1.646	0.94
399_A	402_P	1.628	0.94
261_V	301_G	1.624	0.93
616_D	619_A	1.618	0.93
401_P	419_S	1.606	0.93
266_R	312_T	1.595	0.93
400_G	416_V	1.576	0.92
533_L	561_E	1.574	0.92
460_F	464_D	1.569	0.92
401_P	409_L	1.561	0.92
250_E	303_L	1.560	0.92
177_H	180_P	1.553	0.92
429_P	451_E	1.545	0.92
96_E	101_P	1.544	0.92
370_A	374_R	1.541	0.92
403_V	412_A	1.540	0.92
407_R	419_S	1.540	0.92
403_V	419_S	1.539	0.91
188_L	191_E	1.537	0.91
523_A	571_V	1.536	0.91
400_G	409_L	1.528	0.91
99_V	104_S	1.456	0.89
437_G	613_V	1.453	0.89
404_I	419_S	1.453	0.89
69_L	77_N	1.449	0.89
404_I	408_D	1.448	0.89
94_A	99_V	1.448	0.89
366_V	372_A	1.437	0.88
356_H	359_G	1.435	0.88
71_G	74_V	1.421	0.88
72_A	76_R	1.418	0.88
407_R	416_V	1.417	0.88
369_D	373_D	1.413	0.88
399_A	412_A	1.411	0.87
114_L	117_A	1.408	0.87
71_G	77_N	1.404	0.87
376_H	556_S	1.392	0.87
141_T	148_T	1.386	0.86
249_P	252_A	1.382	0.86
407_R	412_A	1.380	0.86
405_R	409_L	1.379	0.86
404_I	412_A	1.376	0.86
233_V	295_G	1.373	0.86
407_R	413_L	1.368	0.86
313_V	317_G	1.367	0.86
206_D	209_A	1.366	0.86
405_R	412_A	1.355	0.85
400_G	417_G	1.353	0.85
405_R	414_D	1.346	0.85
97_L	101_P	1.333	0.84
620_T	624_D	1.308	0.83
405_R	419_S	1.301	0.83
433_Y	440_D	1.292	0.82
279_L	323_D	1.287	0.82
512_S	541_P	1.287	0.82
96_E	99_V	1.285	0.82
397_S	408_D	1.277	0.82
72_A	77_N	1.274	0.81
400_G	415_A	1.272	0.81
406_Q	410_E	1.260	0.81
283_A	329_L	1.249	0.80
460_F	468_P	1.248	0.80
401_P	412_A	1.246	0.80
403_V	418_P	1.242	0.80
405_R	413_L	1.241	0.80
370_A	373_D	1.241	0.80
405_R	418_P	1.240	0.80
407_R	417_G	1.237	0.79
121_R	126_D	1.233	0.79
75_L	80_P	1.228	0.79
176_E	180_P	1.227	0.79
403_V	417_G	1.222	0.79
400_G	410_E	1.218	0.78
431_T	491_S	1.216	0.78
403_V	407_R	1.209	0.78
178_A	264_A	1.207	0.78
101_P	105_S	1.206	0.78
90_D	99_V	1.202	0.77
406_Q	409_L	1.198	0.77
457_P	485_A	1.194	0.77
399_A	417_G	1.193	0.77
71_G	75_L	1.192	0.77
472_L	588_L	1.190	0.77
216_P	219_V	1.190	0.77
401_P	413_L	1.187	0.76
94_A	97_L	1.177	0.76
403_V	416_V	1.173	0.76
127_D	131_V	1.168	0.75
346_P	349_R	1.162	0.75
400_G	413_L	1.156	0.75
232_L	307_V	1.150	0.74
426_V	432_T	1.148	0.74
155_V	159_T	1.146	0.74
406_Q	416_V	1.142	0.74
364_D	371_V	1.140	0.73
461_E	464_D	1.138	0.73
403_V	413_L	1.138	0.73
178_A	260_A	1.137	0.73
81_T	84_V	1.134	0.73
400_G	412_A	1.132	0.73
365_A	375_T	1.131	0.73
487_A	490_A	1.130	0.73
327_P	533_L	1.128	0.73
403_V	415_A	1.118	0.72
399_A	410_E	1.114	0.72
122_H	130_A	1.112	0.72
232_L	341_V	1.111	0.72
476_P	583_V	1.111	0.72
411_A	418_P	1.109	0.71
375_T	386_V	1.100	0.71
302_W	305_D	1.100	0.71
400_G	403_V	1.095	0.70
455_R	460_F	1.094	0.70
497_L	529_A	1.094	0.70
220_L	279_L	1.093	0.70
90_D	94_A	1.093	0.70
143_D	148_T	1.093	0.70
487_A	584_D	1.089	0.70
298_S	302_W	1.088	0.70
139_V	144_V	1.080	0.69
126_D	129_I	1.079	0.69
486_K	533_L	1.079	0.69
504_L	518_D	1.077	0.69
410_E	414_D	1.075	0.69
117_A	120_G	1.075	0.69
262_L	472_L	1.072	0.69
123_L	127_D	1.065	0.68
220_L	303_L	1.064	0.68
243_A	533_L	1.063	0.68
213_V	216_P	1.060	0.68
470_G	562_L	1.056	0.68
443_K	446_V	1.056	0.68
505_M	542_A	1.054	0.67
91_P	99_V	1.050	0.67
314_V	317_G	1.043	0.67
207_S	221_V	1.039	0.66
310_H	318_E	1.038	0.66
73_D	77_N	1.035	0.66
167_A	173_A	1.032	0.66
96_E	104_S	1.029	0.66
442_A	597_V	1.026	0.65
354_D	369_D	1.024	0.65
405_R	416_V	1.022	0.65
404_I	416_V	1.018	0.65
91_P	96_E	1.017	0.65
369_D	374_R	1.014	0.64
401_P	405_R	1.014	0.64
472_L	597_V	1.006	0.64
400_G	418_P	1.006	0.64
507_R	542_A	1.006	0.64
399_A	404_I	1.005	0.64
561_E	597_V	1.005	0.64
428_T	446_V	1.002	0.63
121_R	134_F	1.001	0.63
446_V	522_R	1.000	0.63
536_V	579_R	0.998	0.63
69_L	72_A	0.997	0.63
184_R	593_I	0.996	0.63
154_T	158_D	0.994	0.63
116_R	120_G	0.993	0.63
92_S	96_E	0.991	0.63
66_S	70_A	0.991	0.63
400_G	407_R	0.990	0.62
165_G	168_A	0.988	0.62
600_P	606_A	0.988	0.62
616_D	624_D	0.979	0.62
401_P	415_A	0.979	0.62
368_L	387_L	0.974	0.61
121_R	128_R	0.970	0.61
505_M	556_S	0.970	0.61
557_Q	582_S	0.968	0.61
541_P	555_V	0.967	0.61
562_L	593_I	0.961	0.60
189_D	194_A	0.959	0.60
513_E	588_L	0.958	0.60
152_P	158_D	0.957	0.60
399_A	405_R	0.956	0.60
305_D	308_R	0.956	0.60
399_A	416_V	0.954	0.60
615_L	618_V	0.953	0.60
526_L	584_D	0.950	0.59
202_P	239_A	0.947	0.59
128_R	134_F	0.947	0.59
209_A	233_V	0.939	0.58
445_E	618_V	0.937	0.58
98_T	101_P	0.936	0.58
404_I	410_E	0.935	0.58
67_S	71_G	0.934	0.58
197_R	204_V	0.931	0.58
435_D	483_M	0.930	0.58
436_I	533_L	0.930	0.58
406_Q	417_G	0.929	0.58
504_L	558_L	0.928	0.57
365_A	374_R	0.926	0.57
159_T	597_V	0.925	0.57
288_A	298_S	0.921	0.57
209_A	392_T	0.918	0.57
111_A	120_G	0.917	0.57
407_R	418_P	0.915	0.56
536_V	582_S	0.915	0.56
477_P	498_S	0.915	0.56
158_D	164_T	0.914	0.56
499_V	563_D	0.910	0.56
66_S	73_D	0.908	0.56
415_A	418_P	0.908	0.56
405_R	410_E	0.905	0.56
103_T	106_T	0.905	0.56
77_N	81_T	0.904	0.55
398_A	405_R	0.903	0.55
258_L	522_R	0.903	0.55
91_P	98_T	0.899	0.55
173_A	205_A	0.898	0.55
252_A	315_V	0.897	0.55
115_A	119_A	0.897	0.55
148_T	151_G	0.895	0.55
433_Y	443_K	0.893	0.55
410_E	415_A	0.892	0.54
65_A	72_A	0.892	0.54
378_Y	554_V	0.891	0.54
72_A	75_L	0.891	0.54
91_P	101_P	0.888	0.54
358_D	362_L	0.886	0.54
263_D	266_R	0.885	0.54
466_A	533_L	0.883	0.54
91_P	125_A	0.881	0.54
215_P	256_D	0.878	0.53
92_S	95_A	0.878	0.53
125_A	128_R	0.872	0.53
250_E	282_A	0.870	0.53
100_A	103_T	0.869	0.53
400_G	405_R	0.869	0.53
295_G	298_S	0.867	0.52
275_F	469_T	0.867	0.52
91_P	113_A	0.866	0.52
101_P	109_G	0.861	0.52
421_L	424_A	0.857	0.51
618_V	624_D	0.856	0.51
116_R	119_A	0.854	0.51
91_P	97_L	0.853	0.51
122_H	127_D	0.851	0.51
298_S	301_G	0.851	0.51
67_S	72_A	0.851	0.51
451_E	491_S	0.848	0.51
66_S	77_N	0.848	0.51
399_A	409_L	0.847	0.51
400_G	419_S	0.846	0.51
146_D	150_G	0.846	0.51
75_L	79_G	0.846	0.51
365_A	371_V	0.843	0.50
399_A	415_A	0.841	0.50
399_A	418_P	0.837	0.50
408_D	412_A	0.835	0.50
399_A	413_L	0.835	0.50
561_E	569_G	0.832	0.49
94_A	512_S	0.829	0.49
407_R	415_A	0.826	0.49
85_T	89_A	0.820	0.48
127_D	134_F	0.819	0.48
97_L	119_A	0.819	0.48
86_V	89_A	0.818	0.48
312_T	390_A	0.817	0.48
160_A	166_H	0.816	0.48
129_I	133_L	0.812	0.48
67_S	77_N	0.811	0.48
411_A	415_A	0.810	0.48
199_V	373_D	0.810	0.48
85_T	88_P	0.809	0.47
402_P	415_A	0.809	0.47
74_V	80_P	0.809	0.47
315_V	505_M	0.809	0.47
435_D	490_A	0.809	0.47
399_A	419_S	0.808	0.47
76_R	80_P	0.805	0.47
82_D	88_P	0.805	0.47
401_P	417_G	0.804	0.47
158_D	162_T	0.804	0.47
398_A	402_P	0.804	0.47
144_V	147_T	0.802	0.47
115_A	118_L	0.802	0.47
206_D	389_D	0.802	0.47
113_A	130_A	0.800	0.47
124_V	130_A	0.800	0.47
114_L	134_F	0.799	0.47
618_V	621_G	0.798	0.46
469_T	558_L	0.797	0.46
558_L	561_E	0.795	0.46
70_A	74_V	0.793	0.46
101_P	104_S	0.793	0.46
201_A	204_V	0.792	0.46
98_T	102_A	0.791	0.46
100_A	105_S	0.791	0.46
76_R	88_P	0.791	0.46
112_D	116_R	0.790	0.46
198_L	204_V	0.790	0.46
114_L	119_A	0.789	0.46
153_V	165_G	0.789	0.46
161_I	164_T	0.788	0.46
211_I	216_P	0.786	0.45
302_W	308_R	0.786	0.45
185_V	245_E	0.786	0.45
255_R	259_A	0.786	0.45
230_T	277_E	0.784	0.45
68_G	84_V	0.782	0.45
609_A	612_E	0.782	0.45
163_L	166_H	0.781	0.45
246_S	260_A	0.780	0.45
82_D	85_T	0.780	0.45
95_A	101_P	0.779	0.45
207_S	341_V	0.778	0.45
83_T	89_A	0.777	0.45
97_L	125_A	0.777	0.45
120_G	134_F	0.774	0.44
117_A	130_A	0.772	0.44
365_A	368_L	0.771	0.44
618_V	623_I	0.770	0.44
72_A	78_V	0.770	0.44
503_E	559_L	0.769	0.44
440_D	444_R	0.769	0.44
541_P	582_S	0.766	0.44
470_G	473_L	0.765	0.44
221_V	567_P	0.764	0.44
154_T	163_L	0.762	0.43
469_T	582_S	0.760	0.43
143_D	195_L	0.756	0.43
65_A	74_V	0.751	0.43
364_D	370_A	0.750	0.42
120_G	128_R	0.746	0.42
143_D	151_G	0.746	0.42
211_I	217_A	0.745	0.42
469_T	492_T	0.744	0.42
595_T	613_V	0.742	0.42
78_V	232_L	0.738	0.41
64_A	70_A	0.737	0.41
94_A	118_L	0.736	0.41
162_T	165_G	0.736	0.41
97_L	100_A	0.735	0.41
90_D	116_R	0.735	0.41
101_P	106_T	0.735	0.41
74_V	78_V	0.732	0.41
130_A	134_F	0.732	0.41
422_R	426_V	0.730	0.41
475_G	481_K	0.728	0.41
396_G	404_I	0.728	0.41
256_D	486_K	0.727	0.41
433_Y	493_D	0.726	0.40
523_A	581_E	0.725	0.40
95_A	99_V	0.725	0.40
433_Y	446_V	0.724	0.40
358_D	366_V	0.724	0.40
582_S	617_G	0.724	0.40
94_A	101_P	0.723	0.40
128_R	133_L	0.722	0.40
189_D	192_R	0.720	0.40
158_D	161_I	0.720	0.40
362_L	497_L	0.718	0.40
180_P	188_L	0.717	0.40
520_F	526_L	0.716	0.40
124_V	155_V	0.715	0.40
402_P	405_R	0.715	0.40
437_G	443_K	0.714	0.40
141_T	145_E	0.712	0.39
405_R	415_A	0.712	0.39
167_A	171_G	0.712	0.39
142_L	151_G	0.708	0.39
342_G	526_L	0.708	0.39
563_D	611_F	0.708	0.39
180_P	185_V	0.707	0.39
532_F	576_A	0.707	0.39
233_V	341_V	0.707	0.39
66_S	72_A	0.705	0.39
115_A	120_G	0.705	0.39
103_T	485_A	0.704	0.39
163_L	172_H	0.704	0.39
121_R	125_A	0.703	0.39
84_V	88_P	0.703	0.39
102_A	106_T	0.702	0.39
65_A	68_G	0.700	0.38
214_R	219_V	0.699	0.38
163_L	171_G	0.699	0.38
134_F	151_G	0.699	0.38
475_G	478_G	0.698	0.38
478_G	481_K	0.698	0.38
556_S	607_R	0.698	0.38
125_A	130_A	0.697	0.38
394_A	397_S	0.696	0.38
64_A	71_G	0.695	0.38
73_D	76_R	0.693	0.38
393_R	436_I	0.693	0.38
129_I	140_V	0.693	0.38
96_E	100_A	0.692	0.38
315_V	391_A	0.692	0.38
314_V	448_R	0.690	0.38
144_V	149_P	0.688	0.37
119_A	134_F	0.688	0.37
83_T	87_A	0.686	0.37
70_A	77_N	0.685	0.37
354_D	365_A	0.684	0.37
449_T	468_P	0.683	0.37
123_L	132_P	0.683	0.37
91_P	128_R	0.681	0.37
340_R	526_L	0.680	0.37
73_D	80_P	0.679	0.37
233_V	505_M	0.679	0.37
87_A	90_D	0.678	0.37
74_V	81_T	0.677	0.37
437_G	588_L	0.677	0.37
407_R	414_D	0.676	0.36
91_P	114_L	0.675	0.36
529_A	573_V	0.675	0.36
239_A	522_R	0.674	0.36
411_A	419_S	0.673	0.36
474_H	601_I	0.672	0.36
406_Q	412_A	0.672	0.36
73_D	78_V	0.671	0.36
99_V	106_T	0.671	0.36
499_V	518_D	0.669	0.36
167_A	170_S	0.667	0.36
400_G	404_I	0.663	0.35
122_H	125_A	0.663	0.35
299_A	308_R	0.663	0.35
265_A	274_V	0.661	0.35
612_E	625_T	0.660	0.35
68_G	74_V	0.659	0.35
99_V	105_S	0.659	0.35
122_H	128_R	0.658	0.35
258_L	274_V	0.657	0.35
408_D	419_S	0.657	0.35
315_V	318_E	0.657	0.35
402_P	417_G	0.655	0.35
200_V	204_V	0.654	0.35
202_P	348_A	0.653	0.35
140_V	148_T	0.652	0.35
497_L	554_V	0.651	0.35
119_A	132_P	0.651	0.35
121_R	133_L	0.651	0.35
299_A	306_R	0.650	0.34
169_D	597_V	0.650	0.34
68_G	72_A	0.649	0.34
313_V	320_T	0.649	0.34
119_A	122_H	0.648	0.34
136_G	607_R	0.647	0.34
70_A	73_D	0.646	0.34
314_V	318_E	0.644	0.34
485_A	557_Q	0.642	0.34
110_D	146_D	0.642	0.34
566_S	610_I	0.642	0.34
220_L	579_R	0.641	0.34
149_P	154_T	0.640	0.34
375_T	379_T	0.639	0.34
554_V	577_T	0.639	0.34
346_P	373_D	0.638	0.34
511_E	523_A	0.638	0.34
162_T	168_A	0.636	0.33
113_A	117_A	0.636	0.33
161_I	165_G	0.634	0.33
351_A	362_L	0.633	0.33
192_R	608_A	0.633	0.33
499_V	582_S	0.633	0.33
77_N	80_P	0.632	0.33
299_A	302_W	0.632	0.33
233_V	315_V	0.631	0.33
100_A	106_T	0.630	0.33
100_A	166_H	0.629	0.33
65_A	76_R	0.629	0.33
219_V	352_I	0.628	0.33
215_P	225_A	0.627	0.33
402_P	416_V	0.625	0.33
126_D	397_S	0.625	0.33
162_T	169_D	0.622	0.32
507_R	557_Q	0.622	0.32
67_S	74_V	0.622	0.32
98_T	134_F	0.622	0.32
617_G	621_G	0.622	0.32
305_D	311_D	0.621	0.32
267_D	282_A	0.621	0.32
459_L	561_E	0.621	0.32
403_V	411_A	0.620	0.32
469_T	581_E	0.620	0.32
145_E	148_T	0.619	0.32
232_L	347_A	0.619	0.32
433_Y	487_A	0.618	0.32
142_L	148_T	0.618	0.32
197_R	201_A	0.617	0.32
68_G	86_V	0.616	0.32
70_A	486_K	0.616	0.32
135_S	282_A	0.615	0.32
110_D	117_A	0.613	0.32
479_T	539_L	0.613	0.32
189_D	266_R	0.612	0.32
69_L	75_L	0.611	0.32
402_P	412_A	0.610	0.31
436_I	611_F	0.610	0.31
67_S	73_D	0.610	0.31
73_D	133_L	0.609	0.31
82_D	86_V	0.609	0.31
522_R	529_A	0.609	0.31
302_W	306_R	0.608	0.31
122_H	134_F	0.608	0.31
74_V	133_L	0.606	0.31
131_V	142_L	0.606	0.31
212_G	484_L	0.606	0.31
491_S	614_Q	0.605	0.31
183_T	282_A	0.604	0.31
86_V	603_D	0.602	0.31
319_T	558_L	0.601	0.31
117_A	122_H	0.601	0.31
244_V	265_A	0.601	0.31
492_T	579_R	0.600	0.31
178_A	251_D	0.599	0.31
330_R	518_D	0.599	0.31
418_P	455_R	0.599	0.31
220_L	327_P	0.598	0.31
223_G	226_G	0.597	0.31
203_L	358_D	0.597	0.31
433_Y	584_D	0.597	0.31
208_Y	394_A	0.597	0.31
607_R	615_L	0.596	0.30
402_P	413_L	0.596	0.30
411_A	416_V	0.596	0.30
116_R	125_A	0.596	0.30
402_P	410_E	0.595	0.30
401_P	411_A	0.594	0.30
258_L	485_A	0.594	0.30
155_V	158_D	0.594	0.30
133_L	136_G	0.594	0.30
324_A	567_P	0.593	0.30
120_G	130_A	0.593	0.30
472_L	575_A	0.592	0.30
165_G	172_H	0.591	0.30
160_A	191_E	0.591	0.30
554_V	624_D	0.591	0.30
495_N	610_I	0.591	0.30
115_A	123_L	0.588	0.30
245_E	345_D	0.587	0.30
67_S	76_R	0.587	0.30
133_L	140_V	0.586	0.30
313_V	318_E	0.586	0.30
299_A	305_D	0.585	0.30
73_D	79_G	0.584	0.30
153_V	159_T	0.583	0.30
311_D	317_G	0.583	0.30
155_V	166_H	0.583	0.30
287_T	572_A	0.582	0.29
373_D	533_L	0.582	0.29
185_V	569_G	0.581	0.29
196_R	214_R	0.581	0.29
338_E	487_A	0.580	0.29
210_A	574_L	0.580	0.29
313_V	359_G	0.578	0.29
168_A	175_A	0.578	0.29
179_T	361_R	0.578	0.29
68_G	71_G	0.577	0.29
144_V	525_R	0.577	0.29
205_A	415_A	0.577	0.29
497_L	531_V	0.576	0.29
509_V	554_V	0.576	0.29
264_A	297_P	0.575	0.29
320_T	388_V	0.575	0.29
80_P	499_V	0.574	0.29
446_V	577_T	0.572	0.29
115_A	132_P	0.571	0.29
196_R	206_D	0.570	0.29
152_P	157_A	0.570	0.29
66_S	71_G	0.570	0.29
196_R	201_A	0.570	0.29
71_G	79_G	0.569	0.29
139_V	142_L	0.569	0.29
457_P	601_I	0.568	0.28
171_G	258_L	0.567	0.28
84_V	89_A	0.567	0.28
100_A	104_S	0.566	0.28
113_A	133_L	0.564	0.28
522_R	557_Q	0.564	0.28
397_S	411_A	0.564	0.28
201_A	311_D	0.563	0.28
399_A	403_V	0.563	0.28
296_S	308_R	0.563	0.28
141_T	149_P	0.562	0.28
165_G	170_S	0.561	0.28
111_A	122_H	0.560	0.28
495_N	613_V	0.560	0.28
512_S	582_S	0.559	0.28
113_A	116_R	0.559	0.28
408_D	418_P	0.559	0.28
501_G	517_R	0.559	0.28
98_T	119_A	0.559	0.28
448_R	452_W	0.559	0.28
197_R	200_V	0.558	0.28
470_G	579_R	0.557	0.28
90_D	95_A	0.556	0.28
526_L	603_D	0.556	0.28
109_G	127_D	0.556	0.28
402_P	408_D	0.555	0.28
68_G	73_D	0.555	0.28
605_D	608_A	0.555	0.28
173_A	180_P	0.554	0.28
311_D	318_E	0.554	0.28
466_A	509_V	0.554	0.28
617_G	624_D	0.554	0.28
234_R	363_A	0.554	0.28
494_A	529_A	0.554	0.28
603_D	615_L	0.553	0.27
401_P	407_R	0.552	0.27
185_V	279_L	0.551	0.27
272_C	531_V	0.551	0.27
369_D	375_T	0.551	0.27
359_G	398_A	0.550	0.27
572_A	581_E	0.549	0.27
603_D	623_I	0.549	0.27
476_P	578_N	0.549	0.27
221_V	341_V	0.548	0.27
101_P	130_A	0.547	0.27
381_A	384_T	0.547	0.27
472_L	563_D	0.546	0.27
460_F	469_T	0.545	0.27
451_E	495_N	0.545	0.27
261_V	485_A	0.544	0.27
297_P	452_W	0.544	0.27
309_G	358_D	0.544	0.27
403_V	408_D	0.544	0.27
465_A	526_L	0.543	0.27
378_Y	616_D	0.542	0.27
372_A	461_E	0.542	0.27
485_A	607_R	0.542	0.27
71_G	80_P	0.541	0.27
205_A	351_A	0.540	0.27
156_T	366_V	0.540	0.27
507_R	556_S	0.539	0.27
433_Y	600_P	0.539	0.27
405_R	408_D	0.537	0.26
77_N	244_V	0.536	0.26
311_D	320_T	0.536	0.26
318_E	322_P	0.536	0.26
511_E	578_N	0.535	0.26
100_A	126_D	0.535	0.26
233_V	275_F	0.534	0.26
402_P	418_P	0.533	0.26
287_T	297_P	0.532	0.26
170_S	175_A	0.532	0.26
555_V	575_A	0.531	0.26
174_D	177_H	0.531	0.26
238_A	484_L	0.531	0.26
220_L	584_D	0.530	0.26
140_V	143_D	0.529	0.26
187_G	363_A	0.529	0.26
411_A	414_D	0.529	0.26
254_D	334_R	0.529	0.26
185_V	188_L	0.528	0.26
169_D	175_A	0.528	0.26
117_A	137_T	0.527	0.26
424_A	554_V	0.526	0.26
447_V	595_T	0.525	0.26
401_P	410_E	0.524	0.26
143_D	149_P	0.524	0.26
367_S	371_V	0.523	0.25
318_E	321_D	0.523	0.25
457_P	597_V	0.522	0.25
140_V	147_T	0.522	0.25
173_A	249_P	0.521	0.25
504_L	536_V	0.521	0.25
125_A	134_F	0.520	0.25
561_E	573_V	0.520	0.25
92_S	105_S	0.519	0.25
225_A	297_P	0.518	0.25
170_S	192_R	0.515	0.25
476_P	598_A	0.515	0.25
499_V	561_E	0.514	0.25
233_V	238_A	0.514	0.25
604_Q	618_V	0.513	0.25
485_A	518_D	0.513	0.25
103_T	127_D	0.513	0.25
346_P	350_R	0.513	0.25
201_A	216_P	0.513	0.25
121_R	124_V	0.513	0.25
155_V	448_R	0.513	0.25
421_L	427_Q	0.512	0.25
100_A	107_L	0.512	0.25
508_Y	563_D	0.512	0.25
440_D	605_D	0.511	0.25
499_V	531_V	0.511	0.25
497_L	522_R	0.510	0.25
153_V	593_I	0.510	0.25
104_S	114_L	0.510	0.25
520_F	579_R	0.509	0.25
436_I	573_V	0.508	0.25
92_S	108_E	0.508	0.25
187_G	495_N	0.508	0.25
300_L	306_R	0.508	0.25
378_Y	460_F	0.508	0.25
164_T	167_A	0.506	0.24
198_L	356_H	0.506	0.24
446_V	536_V	0.506	0.24
196_R	234_R	0.505	0.24
584_D	607_R	0.504	0.24
458_A	519_L	0.503	0.24
514_R	518_D	0.503	0.24
573_V	607_R	0.503	0.24
441_R	513_E	0.502	0.24
528_P	588_L	0.502	0.24
482_T	534_D	0.502	0.24
482_T	535_E	0.502	0.24
478_G	534_D	0.502	0.24
478_G	535_E	0.502	0.24
261_V	275_F	0.501	0.24
366_V	369_D	0.500	0.24

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
3cf2A	3	0.8799	100	0.506	Contact Map
1r6bX	1	0.8799	100	0.646	Contact Map
4d2uA	3	0.8509	100	0.669	Contact Map
1qvrA	3	0.8538	100	0.671	Contact Map
3pxiA	3	0.8408	100	0.686	Contact Map
3cmuA	1	0.9262	100	0.688	Contact Map
4ciuA	1	0.6541	100	0.689	Contact Map
4cr2J	1	0.492	100	0.709	Contact Map
4ko8A	3	0.6382	100	0.71	Contact Map
2x8aA	1	0.3343	100	0.71	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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