Q9HPT7 - HALSA - GREMLIN Contacts

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Q9HPT7 - Uncharacterized protein

UniProt:	Q9HPT7	Sequences: MPKLRSAFASIGDRVQARPVATLLIAGLLILVAIGGAAQITSVTGDDAFVGSNPTYEAFSDSFDHGNIAVLIRGDITEPSAIEAIDRYDRRMSQTQDVYAVRSPADQVRAAYGRIPDSKSKIESVIGSPDYTTIQIATDTDLTQQQQRPIYTEAVSTSDWARFPASVTATVTGDAAFSAQLSTVIQQSTQKLLGLAVGLMVIALFFLFRGVRLRLLPIVAVFVGVIYTFGAIGYGGIPNSTMTSAVFPILIGLGIDYSVQFHERYEEELETHPPREALPNALGGVGPPVLIAMLAAALGFGATWVSTSSPAIIWFAQTSILGVLLTYAAGILVLLAGLTIYIRRWGDDSPAAADGGDPEAAHAEVDEDSRIGLVGSTLGRTSRILASHPMTVLAIALVLSGVGFQVASSLGTLADTEEFIPQDLPAYVDLQQFRSQTGGGTSTSYDVLVTGTHLKHPETLRWMDGLNDVATQAPLVEGVDTPAGAVKQYNGGEIPRTTSGVERVLAQMPTEQRQRYYNDGRAHITVASPQDMTTGQVLSFLENSQESLDYSNPPPGVTAEVTGTSSIAVPSIIDQINSRNTTTGLGILFVFALLGLYYRDLVKAVAPLVPMVFVIGWQNIYMLALDIPVSPLGASLGAMTVGIGAEYTIIVMERYYEEKQHNGYGRLDAVEIAASRVGKAITVSGMTTVFGFSALILSPFPVLSSFGFLTVGVIFLTLIASLATLPPTLVVLDGLAERVAAFRAAD	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	746 (682)
Sequences:	23742 (16734)
Seq/√Len:	640.8

ECOLI - MDTB MDTC CUSA ACRF ACRB ACRD MDTF
BACSU - YDFJ SWRC YDGH SECDF
HALSA - Q9HPT7
SULSO - Q97ZV9

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
665_G	668_D	4.842	1.00
273_P	276_E	4.515	1.00
154_A	157_T	4.228	1.00
82_I	86_D	3.797	1.00
156_S	159_D	3.667	1.00
383_R	671_E	3.659	1.00
621_Y	712_G	3.513	1.00
381_T	723_A	3.462	1.00
13_D	17_A	3.279	1.00
467_N	471_T	3.236	1.00
82_I	85_I	3.059	1.00
83_E	87_R	2.969	1.00
77_T	81_A	2.963	1.00
227_Y	325_L	2.844	1.00
379_G	675_S	2.833	1.00
149_P	183_T	2.812	1.00
664_Y	672_I	2.801	1.00
458_E	461_R	2.694	1.00
658_E	662_N	2.656	1.00
91_R	154_A	2.599	1.00
603_K	656_Y	2.587	1.00
13_D	279_P	2.583	1.00
194_G	198_G	2.581	1.00
658_E	664_Y	2.573	1.00
146_Q	150_I	2.537	1.00
658_E	672_I	2.505	1.00
656_Y	660_Q	2.497	1.00
461_R	465_G	2.494	1.00
17_A	275_R	2.468	1.00
464_D	467_N	2.462	1.00
469_V	472_Q	2.427	1.00
77_T	80_S	2.366	1.00
272_H	280_N	2.350	1.00
388_H	391_T	2.333	1.00
667_L	730_V	2.245	1.00
95_T	150_I	2.242	1.00
536_Q	539_S	2.239	1.00
387_S	667_L	2.224	1.00
297_A	324_L	2.197	1.00
78_E	81_A	2.197	1.00
543_N	546_E	2.188	1.00
473_A	543_N	2.171	1.00
670_V	730_V	2.169	1.00
545_Q	549_D	2.148	1.00
405_Q	408_S	2.147	1.00
118_S	121_K	2.136	1.00
462_W	465_G	2.122	1.00
152_T	174_D	2.111	1.00
276_E	280_N	2.105	1.00
231_A	321_L	2.102	1.00
625_L	708_F	2.100	1.00
149_P	153_E	2.089	1.00
535_G	543_N	2.087	1.00
191_K	195_L	2.026	1.00
159_D	168_T	2.005	1.00
470_A	544_S	1.998	1.00
150_I	153_E	1.984	1.00
76_I	81_A	1.977	1.00
535_G	539_S	1.967	1.00
467_N	479_V	1.929	1.00
293_M	327_Y	1.926	1.00
476_V	479_V	1.925	1.00
89_D	93_S	1.921	1.00
373_L	377_T	1.919	1.00
453_H	458_E	1.907	1.00
465_G	468_D	1.904	1.00
373_L	376_S	1.899	1.00
667_L	671_E	1.897	1.00
384_I	387_S	1.894	1.00
268_E	271_T	1.885	1.00
268_E	284_G	1.875	1.00
465_G	469_V	1.875	1.00
220_A	329_A	1.874	1.00
659_K	729_L	1.872	1.00
123_E	127_G	1.862	1.00
420_I	424_L	1.852	1.00
542_E	546_E	1.849	1.00
39_Q	233_G	1.849	1.00
152_T	156_S	1.842	1.00
404_F	408_S	1.833	1.00
389_P	730_V	1.832	1.00
34_I	38_A	1.823	1.00
426_A	429_D	1.822	1.00
71_L	74_G	1.820	1.00
379_G	383_R	1.816	1.00
67_N	71_L	1.816	1.00
393_L	731_V	1.800	1.00
68_I	71_L	1.799	1.00
384_I	388_H	1.798	1.00
120_S	124_S	1.795	1.00
398_V	402_V	1.782	1.00
429_D	432_Q	1.782	1.00
146_Q	149_P	1.780	1.00
659_K	733_D	1.757	1.00
187_Q	191_K	1.746	1.00
76_I	79_P	1.741	1.00
460_L	464_D	1.739	1.00
67_N	74_G	1.737	1.00
469_V	547_S	1.736	1.00
458_E	462_W	1.736	1.00
542_E	545_Q	1.733	1.00
401_G	405_Q	1.717	1.00
462_W	557_V	1.714	1.00
468_D	471_T	1.706	1.00
267_E	271_T	1.701	1.00
228_T	322_G	1.696	1.00
468_D	472_Q	1.695	1.00
696_I	711_V	1.693	1.00
495_P	504_V	1.686	1.00
453_H	457_P	1.681	1.00
459_T	463_M	1.676	1.00
60_S	524_I	1.669	1.00
539_S	542_E	1.667	1.00
545_Q	573_I	1.663	1.00
689_V	715_F	1.650	1.00
664_Y	668_D	1.648	1.00
128_S	131_Y	1.635	1.00
464_D	468_D	1.633	1.00
591_F	604_A	1.628	1.00
378_L	674_A	1.625	1.00
174_D	179_A	1.623	1.00
20_V	595_G	1.614	1.00
377_T	380_R	1.613	1.00
268_E	280_N	1.605	1.00
153_E	156_S	1.602	1.00
543_N	547_S	1.596	1.00
188_S	191_K	1.595	1.00
380_R	383_R	1.594	1.00
466_L	548_L	1.583	1.00
481_T	491_G	1.576	1.00
264_R	284_G	1.573	1.00
30_I	226_I	1.569	1.00
405_Q	409_S	1.567	1.00
67_N	72_I	1.565	1.00
627_I	708_F	1.551	1.00
391_T	394_A	1.547	1.00
18_R	599_R	1.546	1.00
268_E	272_H	1.543	1.00
427_Y	431_Q	1.541	1.00
150_I	154_A	1.535	1.00
69_A	72_I	1.534	1.00
267_E	676_R	1.529	1.00
124_S	127_G	1.507	1.00
436_Q	440_G	1.503	1.00
237_I	317_Q	1.493	1.00
393_L	397_L	1.489	1.00
473_A	476_V	1.486	1.00
689_V	711_V	1.486	1.00
36_G	230_G	1.482	1.00
68_I	72_I	1.472	1.00
275_R	279_P	1.463	1.00
644_G	717_T	1.459	1.00
394_A	398_V	1.448	1.00
235_G	321_L	1.448	1.00
429_D	440_G	1.443	1.00
463_M	467_N	1.437	1.00
274_P	278_L	1.437	1.00
121_K	124_S	1.432	1.00
400_S	404_F	1.432	1.00
280_N	283_G	1.430	1.00
231_A	235_G	1.429	1.00
55_T	58_A	1.426	1.00
654_R	658_E	1.416	1.00
157_T	160_W	1.416	1.00
394_A	401_G	1.416	1.00
668_D	672_I	1.411	1.00
26_A	333_V	1.409	1.00
265_Y	338_L	1.407	1.00
67_N	73_R	1.404	1.00
198_G	202_I	1.401	1.00
376_S	380_R	1.399	1.00
152_T	171_V	1.390	1.00
83_E	86_D	1.390	1.00
476_V	540_F	1.390	1.00
149_P	152_T	1.386	1.00
143_T	146_Q	1.379	1.00
436_Q	439_G	1.377	1.00
298_L	589_F	1.377	1.00
397_L	401_G	1.373	1.00
655_Y	673_A	1.372	1.00
659_K	666_R	1.371	1.00
610_P	648_T	1.368	1.00
539_S	543_N	1.364	1.00
473_A	547_S	1.363	1.00
290_L	327_Y	1.361	1.00
470_A	476_V	1.346	1.00
23_L	340_I	1.345	1.00
317_Q	321_L	1.344	1.00
183_T	187_Q	1.339	1.00
264_R	267_E	1.339	1.00
72_I	79_P	1.338	1.00
310_P	313_I	1.338	1.00
156_S	160_W	1.336	1.00
153_E	157_T	1.333	1.00
223_V	329_A	1.333	1.00
75_D	78_E	1.332	1.00
14_R	18_R	1.323	1.00
655_Y	670_V	1.321	1.00
257_Y	646_E	1.313	1.00
377_T	381_T	1.309	1.00
548_L	559_A	1.305	1.00
429_D	437_T	1.303	1.00
580_N	584_G	1.301	1.00
450_T	558_T	1.299	1.00
672_I	675_S	1.299	1.00
441_T	444_S	1.291	1.00
201_V	218_I	1.287	1.00
382_S	386_A	1.284	1.00
409_S	623_L	1.281	1.00
148_R	152_T	1.279	1.00
74_G	81_A	1.278	1.00
154_A	158_S	1.276	1.00
431_Q	434_R	1.274	1.00
62_S	65_H	1.274	1.00
622_M	633_G	1.272	1.00
128_S	132_T	1.270	1.00
379_G	671_E	1.269	1.00
88_Y	158_S	1.268	1.00
447_V	450_T	1.265	1.00
298_L	593_L	1.264	1.00
380_R	384_I	1.260	1.00
276_E	279_P	1.255	1.00
381_T	384_I	1.253	1.00
72_I	81_A	1.253	1.00
492_G	495_P	1.248	1.00
84_A	87_R	1.248	1.00
434_R	437_T	1.244	1.00
291_I	593_L	1.243	1.00
68_I	74_G	1.240	1.00
428_V	432_Q	1.239	1.00
16_Q	336_A	1.237	1.00
412_T	538_L	1.232	1.00
16_Q	279_P	1.231	1.00
595_G	604_A	1.229	1.00
671_E	675_S	1.228	1.00
155_V	159_D	1.224	1.00
449_V	466_L	1.220	1.00
402_V	406_V	1.217	1.00
469_V	551_S	1.217	1.00
571_S	574_D	1.215	1.00
120_S	123_E	1.213	1.00
390_M	731_V	1.211	1.00
385_L	727_P	1.208	1.00
307_T	578_S	1.207	1.00
478_G	531_D	1.205	1.00
448_L	451_G	1.202	1.00
398_V	401_G	1.201	1.00
261_F	289_V	1.199	1.00
647_Y	685_G	1.197	1.00
15_V	22_T	1.193	1.00
117_D	121_K	1.191	1.00
174_D	180_Q	1.189	1.00
385_L	392_V	1.187	1.00
378_L	382_S	1.186	1.00
475_L	543_N	1.177	1.00
91_R	157_T	1.176	1.00
36_G	233_G	1.176	1.00
379_G	672_I	1.176	1.00
294_L	593_L	1.175	1.00
278_L	339_T	1.174	1.00
264_R	654_R	1.171	1.00
63_F	66_G	1.170	1.00
540_F	543_N	1.166	1.00
413_L	628_P	1.164	1.00
389_P	734_G	1.162	1.00
257_Y	293_M	1.162	1.00
471_T	479_V	1.162	1.00
76_I	80_S	1.162	1.00
584_G	588_L	1.160	1.00
430_L	434_R	1.160	1.00
30_I	223_V	1.159	1.00
469_V	473_A	1.153	1.00
435_S	439_G	1.151	1.00
457_P	460_L	1.151	1.00
82_I	87_R	1.150	1.00
438_G	441_T	1.146	1.00
446_D	449_V	1.145	1.00
75_D	79_P	1.140	1.00
395_I	399_L	1.137	1.00
261_F	282_L	1.135	1.00
497_T	504_V	1.132	1.00
627_I	704_S	1.128	1.00
327_Y	331_I	1.124	1.00
459_T	462_W	1.123	1.00
426_A	430_L	1.121	1.00
656_Y	659_K	1.120	1.00
338_L	342_I	1.120	1.00
383_R	387_S	1.119	1.00
429_D	433_F	1.118	1.00
367_E	371_I	1.116	1.00
672_I	676_R	1.116	1.00
657_E	662_N	1.116	1.00
421_P	425_P	1.115	1.00
390_M	394_A	1.111	1.00
19_P	340_I	1.109	1.00
429_D	436_Q	1.106	1.00
37_A	190_Q	1.096	1.00
187_Q	190_Q	1.095	1.00
682_T	686_M	1.092	1.00
666_R	670_V	1.090	1.00
696_I	708_F	1.090	1.00
435_S	438_G	1.090	1.00
463_M	526_V	1.089	1.00
77_T	82_I	1.089	1.00
431_Q	435_S	1.088	1.00
544_S	561_V	1.087	1.00
295_A	646_E	1.085	1.00
35_G	39_Q	1.084	1.00
591_F	595_G	1.082	1.00
581_T	584_G	1.080	1.00
577_N	580_N	1.079	1.00
266_E	270_E	1.078	1.00
159_D	169_A	1.077	1.00
96_Q	150_I	1.075	1.00
257_Y	292_A	1.073	1.00
655_Y	729_L	1.071	1.00
625_L	628_P	1.071	1.00
432_Q	436_Q	1.070	1.00
32_V	230_G	1.069	1.00
75_D	81_A	1.068	1.00
72_I	77_T	1.067	1.00
269_L	274_P	1.066	1.00
450_T	560_E	1.062	1.00
279_P	283_G	1.062	1.00
395_I	402_V	1.060	1.00
430_L	436_Q	1.060	1.00
419_F	425_P	1.058	1.00
142_L	147_Q	1.055	1.00
396_A	724_T	1.054	1.00
401_G	404_F	1.054	1.00
304_W	320_I	1.048	1.00
324_L	328_A	1.046	1.00
23_L	601_L	1.046	1.00
432_Q	435_S	1.045	1.00
297_A	320_I	1.043	1.00
447_V	470_A	1.042	1.00
621_Y	708_F	1.041	1.00
437_T	440_G	1.038	1.00
71_L	81_A	1.038	1.00
21_A	596_L	1.037	1.00
432_Q	437_T	1.035	1.00
61_D	64_D	1.034	1.00
264_R	268_E	1.030	1.00
155_V	169_A	1.029	1.00
128_S	140_T	1.028	1.00
11_I	15_V	1.028	1.00
434_R	440_G	1.027	1.00
14_R	21_A	1.021	1.00
588_L	592_A	1.019	1.00
92_M	101_V	1.017	1.00
420_I	425_P	1.016	1.00
570_P	574_D	1.015	1.00
459_T	467_N	1.014	1.00
562_T	570_P	1.012	1.00
420_I	423_D	1.011	1.00
286_G	290_L	1.010	1.00
386_A	671_E	1.007	1.00
620_I	624_A	1.006	1.00
693_S	711_V	1.005	1.00
538_L	542_E	1.003	1.00
372_G	375_G	0.999	1.00
518_N	521_R	0.999	1.00
230_G	233_G	0.999	1.00
267_E	654_R	0.998	1.00
23_L	27_G	0.998	1.00
301_G	320_I	0.996	1.00
13_D	283_G	0.996	1.00
231_A	325_L	0.995	1.00
304_W	317_Q	0.995	1.00
457_P	461_R	0.995	1.00
72_I	75_D	0.993	1.00
67_N	70_V	0.992	1.00
190_Q	194_G	0.992	1.00
69_A	73_R	0.990	1.00
57_E	60_S	0.990	1.00
372_G	376_S	0.988	1.00
546_E	549_D	0.988	1.00
223_V	333_V	0.986	1.00
685_G	718_L	0.985	1.00
180_Q	183_T	0.982	1.00
433_F	436_Q	0.980	1.00
210_G	213_L	0.980	1.00
18_R	21_A	0.976	1.00
428_V	436_Q	0.975	1.00
433_F	440_G	0.973	1.00
470_A	479_V	0.971	1.00
406_V	620_I	0.967	1.00
17_A	279_P	0.966	1.00
427_Y	432_Q	0.966	1.00
657_E	660_Q	0.965	1.00
275_R	339_T	0.964	1.00
389_P	731_V	0.964	1.00
386_A	730_V	0.963	1.00
29_L	227_Y	0.961	1.00
640_T	713_V	0.961	1.00
265_Y	281_A	0.961	1.00
163_F	169_A	0.956	1.00
188_S	703_L	0.955	1.00
733_D	736_A	0.954	1.00
690_F	693_S	0.949	1.00
426_A	433_F	0.949	1.00
448_L	520_G	0.941	1.00
446_D	451_G	0.940	1.00
630_S	633_G	0.939	1.00
436_Q	441_T	0.939	1.00
392_V	395_I	0.938	1.00
429_D	434_R	0.938	1.00
40_I	229_F	0.937	1.00
103_S	106_D	0.935	1.00
369_S	373_L	0.934	1.00
286_G	331_I	0.934	1.00
147_Q	150_I	0.933	1.00
291_I	597_Y	0.933	1.00
618_Q	637_G	0.933	1.00
56_Y	60_S	0.927	1.00
520_G	562_T	0.927	1.00
666_R	734_G	0.927	1.00
426_A	432_Q	0.925	1.00
422_Q	425_P	0.925	1.00
430_L	433_F	0.924	1.00
81_A	84_A	0.923	1.00
685_G	689_V	0.923	1.00
384_I	389_P	0.923	1.00
476_V	530_Q	0.921	1.00
168_T	171_V	0.921	1.00
81_A	85_I	0.921	1.00
406_V	623_L	0.919	1.00
428_V	437_T	0.918	1.00
606_A	728_T	0.914	1.00
296_A	646_E	0.914	1.00
370_R	373_L	0.911	1.00
662_N	672_I	0.903	1.00
230_G	234_Y	0.901	1.00
402_V	405_Q	0.900	1.00
375_G	379_G	0.898	1.00
93_S	100_A	0.897	1.00
284_G	657_E	0.897	1.00
232_I	318_T	0.896	1.00
69_A	74_G	0.895	1.00
91_R	94_Q	0.895	1.00
12_G	16_Q	0.894	1.00
375_G	675_S	0.893	1.00
432_Q	438_G	0.893	1.00
427_Y	440_G	0.893	1.00
415_D	418_E	0.891	1.00
313_I	317_Q	0.890	1.00
431_Q	437_T	0.890	1.00
196_A	200_M	0.890	1.00
591_F	608_L	0.889	1.00
73_R	168_T	0.888	1.00
148_R	179_A	0.888	1.00
38_A	41_T	0.888	1.00
598_Y	649_I	0.886	1.00
376_S	379_G	0.886	1.00
686_M	690_F	0.886	1.00
292_A	327_Y	0.885	1.00
430_L	437_T	0.880	1.00
24_L	592_A	0.880	1.00
434_R	439_G	0.878	1.00
459_T	479_V	0.878	1.00
232_I	237_I	0.872	1.00
61_D	66_G	0.870	1.00
98_V	136_I	0.869	1.00
384_I	392_V	0.864	1.00
378_L	381_T	0.864	1.00
336_A	339_T	0.863	1.00
91_R	162_R	0.862	1.00
179_A	183_T	0.859	1.00
663_G	669_A	0.858	1.00
476_V	480_D	0.858	1.00
271_T	280_N	0.858	1.00
443_T	451_G	0.857	1.00
413_L	630_S	0.856	1.00
79_P	83_E	0.855	1.00
70_V	74_G	0.853	1.00
264_R	285_V	0.853	1.00
265_Y	278_L	0.851	1.00
62_S	66_G	0.848	1.00
16_Q	19_P	0.848	1.00
437_T	441_T	0.848	1.00
666_R	733_D	0.847	1.00
184_V	187_Q	0.844	1.00
654_R	676_R	0.843	1.00
654_R	657_E	0.842	1.00
391_T	395_I	0.841	1.00
60_S	519_D	0.840	1.00
243_T	314_W	0.839	1.00
454_L	457_P	0.838	1.00
89_D	103_S	0.838	1.00
467_N	473_A	0.836	1.00
576_I	580_N	0.835	1.00
104_P	135_Q	0.834	1.00
430_L	439_G	0.833	1.00
659_K	669_A	0.833	1.00
618_Q	709_L	0.831	1.00
205_F	214_R	0.831	1.00
132_T	140_T	0.830	1.00
621_Y	625_L	0.827	1.00
387_S	390_M	0.826	1.00
622_M	709_L	0.826	1.00
429_D	439_G	0.825	1.00
433_F	437_T	0.825	1.00
727_P	730_V	0.823	1.00
228_T	325_L	0.821	1.00
381_T	385_L	0.821	1.00
427_Y	430_L	0.820	1.00
413_L	416_T	0.820	1.00
128_S	133_T	0.819	1.00
95_T	98_V	0.817	1.00
606_A	725_L	0.816	1.00
427_Y	434_R	0.816	1.00
346_G	349_S	0.816	1.00
392_V	396_A	0.816	1.00
435_S	440_G	0.815	1.00
371_I	375_G	0.814	1.00
16_Q	339_T	0.814	1.00
26_A	223_V	0.814	1.00
100_A	137_A	0.813	1.00
101_V	134_I	0.812	1.00
668_D	671_E	0.812	1.00
605_V	609_V	0.804	1.00
95_T	154_A	0.804	1.00
432_Q	440_G	0.803	1.00
523_H	558_T	0.803	1.00
84_A	167_V	0.803	1.00
413_L	418_E	0.803	1.00
428_V	438_G	0.802	1.00
433_F	438_G	0.801	1.00
152_T	155_V	0.801	1.00
462_W	467_N	0.800	1.00
451_G	459_T	0.800	1.00
647_Y	717_T	0.799	1.00
216_L	334_L	0.798	1.00
87_R	91_R	0.798	1.00
128_S	138_T	0.798	1.00
458_E	557_V	0.796	1.00
428_V	431_Q	0.795	1.00
431_Q	436_Q	0.793	1.00
200_M	255_I	0.793	1.00
408_S	411_G	0.792	1.00
26_A	332_L	0.792	1.00
74_G	78_E	0.792	1.00
454_L	459_T	0.791	1.00
155_V	158_S	0.790	1.00
293_M	323_V	0.790	1.00
61_D	72_I	0.787	1.00
68_I	73_R	0.786	1.00
428_V	434_R	0.786	1.00
450_T	525_T	0.784	1.00
651_V	681_I	0.783	1.00
426_A	439_G	0.781	1.00
426_A	438_G	0.780	1.00
320_I	324_L	0.779	1.00
395_I	398_V	0.778	1.00
475_L	535_G	0.776	1.00
272_H	276_E	0.776	1.00
419_F	423_D	0.776	1.00
132_T	135_Q	0.773	1.00
728_T	732_L	0.773	1.00
421_P	424_L	0.772	1.00
436_Q	444_S	0.772	1.00
459_T	476_V	0.772	1.00
228_T	321_L	0.772	1.00
20_V	24_L	0.772	1.00
393_L	727_P	0.772	1.00
219_V	337_G	0.770	1.00
30_I	34_I	0.770	1.00
43_V	238_P	0.770	1.00
730_V	734_G	0.769	1.00
664_Y	669_A	0.768	1.00
390_M	393_L	0.768	1.00
67_N	81_A	0.768	1.00
573_I	577_N	0.767	1.00
12_G	282_L	0.767	1.00
207_L	683_V	0.767	1.00
471_T	474_P	0.766	1.00
592_A	596_L	0.765	1.00
428_V	435_S	0.765	1.00
577_N	581_T	0.764	1.00
211_V	215_L	0.762	1.00
466_L	469_V	0.760	1.00
30_I	227_Y	0.760	1.00
240_S	243_T	0.758	1.00
274_P	277_A	0.758	1.00
625_L	712_G	0.756	1.00
72_I	76_I	0.756	1.00
651_V	674_A	0.756	1.00
693_S	697_L	0.755	1.00
333_V	337_G	0.755	1.00
32_V	36_G	0.752	1.00
554_P	557_V	0.752	1.00
432_Q	439_G	0.750	1.00
400_S	616_G	0.749	1.00
191_K	194_G	0.747	1.00
163_F	167_V	0.746	1.00
296_A	688_T	0.745	1.00
75_D	80_S	0.745	1.00
336_A	340_I	0.744	1.00
427_Y	436_Q	0.744	1.00
35_G	38_A	0.742	1.00
426_A	440_G	0.742	1.00
472_Q	547_S	0.740	1.00
215_L	219_V	0.740	1.00
470_A	473_A	0.739	1.00
334_L	338_L	0.739	1.00
406_V	409_S	0.738	1.00
26_A	329_A	0.738	1.00
451_G	454_L	0.738	1.00
670_V	674_A	0.736	1.00
462_W	470_A	0.736	1.00
721_S	725_L	0.735	1.00
636_L	710_T	0.734	1.00
386_A	727_P	0.732	1.00
219_V	333_V	0.732	1.00
429_D	438_G	0.731	1.00
368_D	371_I	0.731	1.00
20_V	340_I	0.730	1.00
440_G	444_S	0.730	1.00
147_Q	151_Y	0.730	1.00
541_L	545_Q	0.729	1.00
195_L	198_G	0.728	1.00
537_V	540_F	0.728	1.00
532_M	540_F	0.728	1.00
606_A	648_T	0.727	1.00
466_L	470_A	0.724	1.00
61_D	74_G	0.723	1.00
666_R	730_V	0.722	1.00
659_K	664_Y	0.722	1.00
209_R	368_D	0.722	1.00
611_M	641_V	0.722	1.00
216_L	337_G	0.720	1.00
151_Y	155_V	0.719	1.00
460_L	463_M	0.717	1.00
64_D	72_I	0.717	1.00
70_V	73_R	0.716	1.00
470_A	475_L	0.716	1.00
74_G	79_P	0.715	1.00
145_Q	148_R	0.714	1.00
328_A	332_L	0.712	1.00
477_E	480_D	0.712	1.00
19_P	339_T	0.710	1.00
467_N	476_V	0.708	1.00
91_R	158_S	0.708	1.00
14_R	17_A	0.707	1.00
467_N	480_D	0.705	1.00
33_A	227_Y	0.705	1.00
620_I	623_L	0.704	1.00
383_R	667_L	0.704	1.00
85_I	88_Y	0.704	1.00
636_L	709_L	0.704	1.00
467_N	470_A	0.704	1.00
624_A	628_P	0.702	1.00
71_L	80_S	0.701	1.00
545_Q	561_V	0.701	1.00
130_D	140_T	0.700	1.00
163_F	166_S	0.700	1.00
82_I	106_D	0.700	1.00
179_A	182_S	0.698	1.00
678_G	682_T	0.698	1.00
659_K	663_G	0.697	1.00
616_G	716_L	0.697	1.00
152_T	183_T	0.697	1.00
430_L	440_G	0.696	1.00
451_G	458_E	0.696	1.00
461_R	464_D	0.694	1.00
376_S	675_S	0.694	1.00
426_A	436_Q	0.694	1.00
658_E	676_R	0.694	1.00
150_I	155_V	0.694	1.00
237_I	243_T	0.693	1.00
603_K	733_D	0.692	1.00
64_D	74_G	0.691	1.00
473_A	546_E	0.691	1.00
647_Y	721_S	0.691	1.00
151_Y	154_A	0.691	1.00
130_D	134_I	0.691	1.00
446_D	450_T	0.690	1.00
89_D	101_V	0.690	1.00
198_G	205_F	0.689	1.00
459_T	478_G	0.689	1.00
70_V	80_S	0.688	1.00
98_V	147_Q	0.686	1.00
61_D	71_L	0.686	1.00
403_G	620_I	0.685	1.00
665_G	669_A	0.683	1.00
392_V	727_P	0.683	1.00
396_A	613_F	0.682	1.00
92_M	154_A	0.682	1.00
220_A	334_L	0.681	1.00
227_Y	329_A	0.680	1.00
74_G	77_T	0.680	1.00
119_K	123_E	0.679	1.00
216_L	341_Y	0.678	1.00
541_L	573_I	0.676	1.00
708_F	712_G	0.676	1.00
348_D	351_A	0.676	1.00
217_P	262_H	0.675	1.00
595_G	601_L	0.674	1.00
159_D	163_F	0.674	1.00
715_F	719_I	0.673	1.00
130_D	133_T	0.673	1.00
630_S	705_S	0.672	1.00
427_Y	439_G	0.672	1.00
250_L	322_G	0.671	1.00
253_L	688_T	0.670	1.00
426_A	435_S	0.669	1.00
117_D	122_I	0.669	1.00
197_V	251_I	0.669	1.00
601_L	604_A	0.668	1.00
180_Q	184_V	0.668	1.00
87_R	90_R	0.665	1.00
445_Y	451_G	0.665	1.00
67_N	76_I	0.665	1.00
470_A	480_D	0.664	1.00
131_Y	140_T	0.663	1.00
370_R	374_V	0.663	1.00
429_D	441_T	0.662	1.00
62_S	72_I	0.661	1.00
553_P	557_V	0.658	1.00
434_R	438_G	0.658	1.00
70_V	81_A	0.657	1.00
269_L	343_R	0.656	1.00
445_Y	450_T	0.656	1.00
90_R	93_S	0.656	1.00
428_V	433_F	0.656	1.00
718_L	721_S	0.654	1.00
272_H	277_A	0.653	1.00
547_S	551_S	0.653	1.00
447_V	451_G	0.652	1.00
15_V	332_L	0.649	1.00
410_L	623_L	0.649	1.00
590_V	641_V	0.648	1.00
61_D	81_A	0.648	1.00
300_F	319_S	0.648	1.00
61_D	65_H	0.648	1.00
462_W	466_L	0.646	1.00
386_A	670_V	0.646	1.00
86_D	90_R	0.645	1.00
449_V	459_T	0.645	1.00
607_P	652_M	0.644	1.00
145_Q	149_P	0.644	1.00
289_V	327_Y	0.643	1.00
613_F	720_A	0.643	1.00
296_A	323_V	0.642	1.00
426_A	431_Q	0.641	1.00
146_Q	151_Y	0.640	1.00
459_T	557_V	0.640	1.00
689_V	714_I	0.640	1.00
182_S	186_Q	0.639	1.00
541_L	561_V	0.638	1.00
451_G	463_M	0.638	1.00
92_M	95_T	0.637	1.00
262_H	338_L	0.637	1.00
459_T	466_L	0.637	1.00
102_R	137_A	0.637	1.00
419_F	424_L	0.637	1.00
429_D	435_S	0.636	1.00
152_T	159_D	0.636	1.00
385_L	723_A	0.634	1.00
49_F	52_S	0.634	1.00
535_G	540_F	0.633	1.00
133_T	136_I	0.631	1.00
403_G	406_V	0.631	1.00
23_L	337_G	0.630	1.00
602_V	735_L	0.630	1.00
16_Q	275_R	0.628	1.00
36_G	39_Q	0.627	1.00
655_Y	666_R	0.627	1.00
430_L	435_S	0.627	1.00
403_G	619_N	0.625	1.00
454_L	458_E	0.625	1.00
371_I	376_S	0.624	1.00
134_I	140_T	0.623	1.00
445_Y	448_L	0.622	1.00
246_V	319_S	0.622	1.00
369_S	372_G	0.622	1.00
545_Q	559_A	0.621	1.00
685_G	714_I	0.621	1.00
253_L	257_Y	0.619	1.00
435_S	441_T	0.619	1.00
540_F	544_S	0.618	1.00
305_V	585_L	0.617	1.00
651_V	673_A	0.617	1.00
666_R	736_A	0.617	1.00
50_V	53_N	0.617	1.00
61_D	68_I	0.617	1.00
666_R	735_L	0.616	1.00
476_V	544_S	0.615	1.00
199_L	690_F	0.613	1.00
572_I	576_I	0.612	1.00
462_W	553_P	0.611	1.00
64_D	71_L	0.610	1.00
209_R	214_R	0.609	1.00
433_F	441_T	0.609	1.00
346_G	350_P	0.607	1.00
463_M	479_V	0.606	1.00
449_V	557_V	0.605	1.00
378_L	386_A	0.604	1.00
441_T	445_Y	0.603	1.00
31_L	35_G	0.603	1.00
250_L	253_L	0.603	1.00
274_P	343_R	0.602	1.00
237_I	314_W	0.602	1.00
427_Y	435_S	0.602	1.00
224_G	228_T	0.601	1.00
603_K	606_A	0.600	1.00
433_F	439_G	0.600	1.00
591_F	601_L	0.599	1.00
60_S	517_Y	0.598	1.00
152_T	179_A	0.597	1.00
720_A	724_T	0.597	1.00
541_L	565_S	0.597	1.00
131_Y	138_T	0.597	1.00
148_R	174_D	0.597	1.00
285_V	293_M	0.596	1.00
85_I	132_T	0.596	1.00
658_E	663_G	0.595	1.00
400_S	403_G	0.595	1.00
465_G	551_S	0.593	1.00
553_P	559_A	0.592	1.00
304_W	316_A	0.592	1.00
731_V	735_L	0.591	1.00
385_L	388_H	0.591	1.00
55_T	60_S	0.591	1.00
692_F	710_T	0.591	1.00
85_I	167_V	0.589	1.00
451_G	557_V	0.589	1.00
144_Q	147_Q	0.588	1.00
133_T	137_A	0.588	1.00
28_L	32_V	0.587	1.00
426_A	441_T	0.586	1.00
400_S	613_F	0.586	1.00
46_D	53_N	0.584	1.00
367_E	370_R	0.584	1.00
446_D	527_A	0.584	1.00
410_L	416_T	0.583	1.00
86_D	89_D	0.583	1.00
332_L	336_A	0.582	1.00
16_Q	278_L	0.581	1.00
77_T	84_A	0.580	1.00
622_M	627_I	0.578	1.00
295_A	645_A	0.578	1.00
213_L	266_E	0.578	1.00
92_M	134_I	0.576	1.00
129_P	132_T	0.575	1.00
195_L	199_L	0.573	1.00
716_L	720_A	0.572	1.00
62_S	74_G	0.572	1.00
65_H	72_I	0.571	1.00
40_I	239_N	0.570	1.00
466_L	528_S	0.570	1.00
632_L	702_V	0.570	1.00
504_V	507_Q	0.570	1.00
383_R	668_D	0.569	1.00
667_L	670_V	0.569	1.00
123_E	126_I	0.568	1.00
447_V	559_A	0.567	1.00
293_M	297_A	0.566	1.00
260_Q	650_I	0.566	1.00
40_I	233_G	0.566	1.00
459_T	473_A	0.566	1.00
382_S	674_A	0.565	1.00
66_G	72_I	0.565	1.00
718_L	722_L	0.564	1.00
407_A	619_N	0.563	1.00
227_Y	231_A	0.563	1.00
396_A	400_S	0.562	1.00
732_L	735_L	0.562	1.00
132_T	138_T	0.562	1.00
507_Q	510_T	0.562	1.00
693_S	696_I	0.561	1.00
393_L	724_T	0.561	1.00
252_G	256_D	0.560	1.00
274_P	344_R	0.558	1.00
390_M	401_G	0.558	1.00
240_S	314_W	0.558	1.00
128_S	134_I	0.557	1.00
94_Q	154_A	0.557	1.00
496_R	505_L	0.555	1.00
325_L	329_A	0.554	1.00
73_R	76_I	0.553	1.00
210_G	266_E	0.553	1.00
643_I	688_T	0.552	1.00
12_G	286_G	0.552	1.00
278_L	338_L	0.551	1.00
181_L	185_I	0.551	1.00
530_Q	540_F	0.550	1.00
517_Y	521_R	0.550	1.00
180_Q	426_A	0.550	1.00
534_T	537_V	0.548	1.00
648_T	725_L	0.548	1.00
192_L	195_L	0.547	1.00
517_Y	524_I	0.547	1.00
459_T	480_D	0.547	1.00
389_P	667_L	0.546	1.00
666_R	669_A	0.545	1.00
430_L	438_G	0.545	1.00
23_L	333_V	0.545	1.00
620_I	716_L	0.544	1.00
73_R	81_A	0.543	1.00
250_L	319_S	0.542	1.00
462_W	554_P	0.542	1.00
377_T	384_I	0.542	1.00
610_P	613_F	0.542	1.00
465_G	552_N	0.541	1.00
426_A	434_R	0.541	1.00
681_I	685_G	0.541	1.00
471_T	478_G	0.540	1.00
696_I	704_S	0.540	1.00
368_D	372_G	0.539	1.00
81_A	86_D	0.537	0.99
524_I	528_S	0.537	0.99
253_L	687_T	0.537	0.99
719_I	723_A	0.537	0.99
452_T	459_T	0.537	0.99
700_F	703_L	0.537	0.99
382_S	385_L	0.536	0.99
449_V	559_A	0.536	0.99
329_A	332_L	0.535	0.99
246_V	250_L	0.534	0.99
553_P	556_G	0.534	0.99
195_L	202_I	0.534	0.99
616_G	620_I	0.534	0.99
633_G	709_L	0.534	0.99
542_E	573_I	0.533	0.99
12_G	283_G	0.533	0.99
428_V	439_G	0.533	0.99
493_E	496_R	0.532	0.99
610_P	725_L	0.531	0.99
582_T	586_G	0.531	0.99
463_M	469_V	0.531	0.99
413_L	417_E	0.531	0.99
179_A	186_Q	0.531	0.99
615_I	619_N	0.530	0.99
34_I	37_A	0.530	0.99
659_K	665_G	0.529	0.99
264_R	281_A	0.529	0.99
90_R	94_Q	0.528	0.99
458_E	556_G	0.527	0.99
182_S	185_I	0.527	0.99
583_T	634_A	0.526	0.99
41_T	238_P	0.526	0.99
692_F	711_V	0.526	0.99
56_Y	59_F	0.526	0.99
289_V	331_I	0.525	0.99
445_Y	449_V	0.525	0.99
131_Y	134_I	0.525	0.99
80_S	84_A	0.524	0.99
20_V	601_L	0.524	0.99
254_G	323_V	0.523	0.99
520_G	525_T	0.523	0.99
717_T	721_S	0.523	0.99
460_L	526_V	0.523	0.99
97_D	150_I	0.522	0.99
259_V	683_V	0.522	0.99
404_F	616_G	0.522	0.99
403_G	407_A	0.522	0.99
472_Q	476_V	0.522	0.99
428_V	440_G	0.521	0.99
36_G	234_Y	0.521	0.99
46_D	54_P	0.521	0.99
439_G	443_T	0.521	0.99
663_G	668_D	0.520	0.99
292_A	687_T	0.520	0.99
92_M	136_I	0.519	0.99
269_L	277_A	0.519	0.99
134_I	137_A	0.519	0.99
647_Y	684_S	0.518	0.99
399_L	616_G	0.518	0.99
71_L	77_T	0.518	0.99
414_A	418_E	0.517	0.99
403_G	616_G	0.517	0.99
546_E	551_S	0.517	0.99
590_V	645_A	0.516	0.99
419_F	422_Q	0.516	0.99
399_L	403_G	0.516	0.99
544_S	547_S	0.516	0.99
135_Q	140_T	0.515	0.99
371_I	378_L	0.515	0.99
467_N	528_S	0.515	0.99
470_A	474_P	0.514	0.99
446_D	452_T	0.513	0.99
337_G	341_Y	0.512	0.99
77_T	85_I	0.512	0.99
462_W	480_D	0.512	0.99
374_V	377_T	0.512	0.99
386_A	667_L	0.511	0.99
202_I	205_F	0.511	0.99
217_P	255_I	0.510	0.99
459_T	470_A	0.510	0.99
397_L	404_F	0.509	0.99
434_R	441_T	0.509	0.99
269_L	273_P	0.509	0.99
224_G	325_L	0.508	0.99
66_G	69_A	0.508	0.99
74_G	80_S	0.508	0.99
458_E	465_G	0.508	0.99
528_S	532_M	0.507	0.99
72_I	78_E	0.507	0.99
345_W	349_S	0.507	0.99
466_L	473_A	0.507	0.99
213_L	217_P	0.506	0.99
185_I	189_T	0.506	0.99
453_H	463_M	0.506	0.99
387_S	391_T	0.505	0.99
76_I	84_A	0.505	0.99
246_V	322_G	0.504	0.99
292_A	646_E	0.504	0.99
644_G	647_Y	0.504	0.99
108_V	111_A	0.504	0.99
32_V	35_G	0.504	0.99
72_I	85_I	0.503	0.99
462_W	478_G	0.503	0.99
245_A	703_L	0.502	0.99
463_M	466_L	0.502	0.99
316_A	320_I	0.501	0.99
13_D	276_E	0.501	0.99
189_T	192_L	0.501	0.99
267_E	284_G	0.501	0.99
674_A	678_G	0.501	0.99
288_P	657_E	0.500	0.99
260_Q	285_V	0.500	0.99
665_G	670_V	0.500	0.99

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
4k0jA	3	0.8995	100	0.398	Contact Map
4dx5A	3	0.9517	100	0.442	Contact Map
3w9iA	3	0.941	100	0.445	Contact Map
3ne5A	3	0.9236	100	0.447	Contact Map
4mt1A	3	0.9169	100	0.451	Contact Map
3aqpA	1	0.7989	100	0.568	Contact Map
4r86A	1	0.2198	78.6	0.965	Contact Map
2kncA	1	0.063	13.7	0.978	Contact Map
4yayA	1	0.3445	13.7	0.978	Contact Map
2kwaA	1	0.1166	12.4	0.978	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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