Q9HPS4 - HALSA - GREMLIN Contacts

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Q9HPS4 - Amidophosphoribosyltransferase

UniProt:	Q9HPS4	Sequences: MSGGPADGPMSDHPTEKCGVVGASLSARDAALPTYYALYALQHRGQESAGIVAHDGFQQHQHVGMGLVGDAFDEADIDALHGSAAIGHVRYPTAGSVDKSCAQPFSVSFKGGALGLSHNGNLVNADELRADLAASGHAFTSDGDTEVIAHDLARNLLDADLVDAVERTMERIHGSYSLTIMHDDTVLGVRDPRGNRPLVLGTVEDGYVIASESAAIDTIGGDVVRDVRPGEAIVLDDDGTGFSAHQLVDRDTTAHCFFEYVYFARPDSVIDDELVYEVRRNLGRQLWHETGVESDVVVPVPDSGRAFASGYADAATEDGSDVEFAEGLMKNRYVGRTFIMPTQEARERAVRLKLNPIKSTVEGQSVTIIDDSIVRGTTSSQLVDLVRDAGATEVHVRIGAPQIQAPCYFGIDMATREELIAADRTADEIAAEIGADSLSYLPLSAVTAAIGKSEADMCAGCVTGAYPYDVDGEATDRDAERPTVTPSSDD	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	490 (382)
Sequences:	6892 (3529)
Seq/√Len:	180.5

ECOLI - PUR1 GLMS
BACSU - PUR1 GLMS
HALSA - Q9HPS4 GLMS
SULSO - Q7LXR4 Q7LXR3 Q980D3 Q97YQ6

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
131_D	171_R	4.954	1.00
135_S	154_R	4.383	1.00
34_T	85_A	3.772	1.00
296_V	332_R	3.093	1.00
160_D	163_D	3.006	1.00
364_Q	377_T	2.973	1.00
244_A	248_V	2.928	1.00
300_V	310_G	2.886	1.00
188_G	209_I	2.868	1.00
39_Y	72_F	2.854	1.00
152_L	168_T	2.837	1.00
155_N	167_R	2.820	1.00
353_K	376_G	2.711	1.00
165_V	190_R	2.695	1.00
280_R	284_R	2.586	1.00
393_E	396_V	2.573	1.00
52_V	59_Q	2.535	1.00
288_H	314_A	2.410	1.00
281_N	284_R	2.343	1.00
155_N	171_R	2.342	1.00
148_I	172_I	2.281	1.00
191_D	209_I	2.270	1.00
64_G	99_K	2.232	1.00
52_V	61_Q	2.228	1.00
185_T	188_G	2.175	1.00
200_L	227_V	2.135	1.00
200_L	233_I	2.134	1.00
65_M	97_V	2.125	1.00
202_T	222_D	2.122	1.00
188_G	234_V	2.104	1.00
191_D	233_I	2.074	1.00
148_I	178_L	2.050	1.00
162_V	243_S	2.030	1.00
137_H	154_R	2.025	1.00
137_H	150_H	2.004	1.00
137_H	153_A	1.982	1.00
53_A	82_G	1.969	1.00
209_I	235_L	1.956	1.00
34_T	87_G	1.949	1.00
64_G	74_E	1.948	1.00
162_V	234_V	1.931	1.00
236_D	239_G	1.914	1.00
161_L	190_R	1.899	1.00
161_L	182_H	1.889	1.00
202_T	224_V	1.866	1.00
21_V	37_A	1.847	1.00
113_A	184_D	1.845	1.00
296_V	330_K	1.793	1.00
69_G	73_D	1.792	1.00
130_A	134_A	1.790	1.00
165_V	180_I	1.769	1.00
358_K	362_E	1.761	1.00
310_G	339_I	1.750	1.00
52_V	115_G	1.717	1.00
207_Y	240_T	1.704	1.00
127_E	173_H	1.683	1.00
203_V	206_G	1.676	1.00
365_S	393_E	1.662	1.00
269_V	274_L	1.658	1.00
36_Y	218_T	1.631	1.00
110_K	137_H	1.610	1.00
107_V	111_G	1.606	1.00
116_L	149_A	1.590	1.00
152_L	165_V	1.587	1.00
152_L	180_I	1.581	1.00
84_A	181_M	1.568	1.00
48_S	102_A	1.562	1.00
113_A	183_D	1.561	1.00
100_S	142_D	1.560	1.00
155_N	168_T	1.560	1.00
354_L	357_I	1.550	1.00
110_K	153_A	1.550	1.00
282_L	402_Q	1.547	1.00
70_D	73_D	1.539	1.00
200_L	240_T	1.531	1.00
222_D	254_A	1.513	1.00
293_E	365_S	1.504	1.00
163_D	166_E	1.494	1.00
227_V	233_I	1.489	1.00
202_T	207_Y	1.474	1.00
129_R	133_A	1.470	1.00
182_H	185_T	1.457	1.00
384_D	388_D	1.440	1.00
200_L	209_I	1.436	1.00
285_Q	288_H	1.429	1.00
65_M	98_D	1.411	1.00
117_S	179_T	1.410	1.00
305_R	393_E	1.401	1.00
330_K	334_V	1.401	1.00
194_G	230_G	1.392	1.00
55_D	58_Q	1.390	1.00
338_F	352_L	1.389	1.00
285_Q	383_V	1.386	1.00
156_L	159_A	1.383	1.00
114_L	182_H	1.380	1.00
255_H	259_E	1.375	1.00
59_Q	115_G	1.374	1.00
295_D	335_G	1.374	1.00
339_I	404_Q	1.371	1.00
130_A	133_A	1.363	1.00
281_N	399_G	1.363	1.00
53_A	85_A	1.362	1.00
179_T	209_I	1.357	1.00
106_S	115_G	1.345	1.00
207_Y	239_G	1.341	1.00
284_R	314_A	1.338	1.00
256_C	259_E	1.338	1.00
336_R	360_T	1.317	1.00
162_V	232_A	1.317	1.00
69_G	72_F	1.315	1.00
107_V	137_H	1.315	1.00
26_S	30_A	1.310	1.00
179_T	189_V	1.288	1.00
63_V	99_K	1.284	1.00
17_K	20_V	1.273	1.00
162_V	166_E	1.273	1.00
54_H	181_M	1.265	1.00
31_A	51_I	1.264	1.00
167_R	170_E	1.263	1.00
169_M	172_I	1.259	1.00
75_A	79_A	1.253	1.00
307_F	311_Y	1.251	1.00
199_V	216_I	1.248	1.00
366_V	374_V	1.246	1.00
210_A	215_A	1.243	1.00
131_D	135_S	1.242	1.00
129_R	139_F	1.238	1.00
202_T	240_T	1.230	1.00
216_I	221_G	1.227	1.00
31_A	82_G	1.224	1.00
35_Y	51_I	1.224	1.00
350_V	377_T	1.223	1.00
187_L	237_D	1.211	1.00
188_G	236_D	1.209	1.00
329_M	360_T	1.201	1.00
23_A	33_P	1.200	1.00
74_E	99_K	1.197	1.00
22_G	179_T	1.196	1.00
116_L	145_T	1.195	1.00
73_D	76_D	1.190	1.00
231_E	252_T	1.187	1.00
126_D	130_A	1.180	1.00
267_D	276_Y	1.175	1.00
191_D	200_L	1.174	1.00
213_S	226_D	1.174	1.00
22_G	209_I	1.162	1.00
292_V	397_R	1.161	1.00
114_L	156_L	1.159	1.00
346_R	350_V	1.144	1.00
364_Q	367_T	1.143	1.00
156_L	182_H	1.141	1.00
199_V	213_S	1.138	1.00
273_E	278_V	1.135	1.00
25_L	84_A	1.125	1.00
106_S	112_G	1.124	1.00
277_E	359_S	1.123	1.00
36_Y	39_Y	1.113	1.00
28_R	206_G	1.100	1.00
374_V	380_S	1.093	1.00
155_N	158_D	1.090	1.00
25_L	237_D	1.086	1.00
336_R	355_N	1.082	1.00
64_G	71_A	1.079	1.00
29_D	32_L	1.078	1.00
53_A	80_L	1.077	1.00
114_L	161_L	1.077	1.00
31_A	53_A	1.073	1.00
23_A	30_A	1.069	1.00
217_D	355_N	1.069	1.00
131_D	154_R	1.067	1.00
383_V	399_G	1.064	1.00
207_Y	235_L	1.057	1.00
18_C	119_N	1.056	1.00
61_Q	106_S	1.054	1.00
62_H	79_A	1.044	1.00
223_V	226_D	1.043	1.00
161_L	165_V	1.041	1.00
163_D	167_R	1.040	1.00
62_H	74_E	1.037	1.00
23_A	26_S	1.037	1.00
297_V	330_K	1.037	1.00
280_R	313_D	1.037	1.00
213_S	223_V	1.036	1.00
164_A	168_T	1.033	1.00
33_P	219_I	1.033	1.00
361_V	379_S	1.032	1.00
254_A	257_F	1.032	1.00
278_V	282_L	1.029	1.00
38_L	87_G	1.027	1.00
236_D	240_T	1.027	1.00
107_V	153_A	1.025	0.99
187_L	234_V	1.022	0.99
294_S	367_T	1.017	0.99
21_V	34_T	1.016	0.99
155_N	164_A	1.011	0.99
338_F	377_T	1.009	0.99
175_S	195_N	1.009	0.99
125_A	129_R	1.004	0.99
374_V	382_L	1.002	0.99
322_V	329_M	1.002	0.99
356_P	378_T	1.000	0.99
168_T	172_I	1.000	0.99
228_R	231_E	0.998	0.99
268_S	272_D	0.997	0.99
323_E	350_V	0.997	0.99
340_M	373_I	0.993	0.99
257_F	261_V	0.992	0.99
369_I	382_L	0.989	0.99
296_V	366_V	0.984	0.99
284_R	313_D	0.981	0.99
362_E	377_T	0.980	0.99
291_G	361_V	0.978	0.99
208_V	216_I	0.975	0.99
209_I	233_I	0.970	0.99
55_D	60_H	0.970	0.99
19_G	89_V	0.965	0.99
166_E	232_A	0.960	0.99
118_H	145_T	0.960	0.99
153_A	157_L	0.955	0.99
200_L	224_V	0.954	0.99
222_D	256_C	0.954	0.99
129_R	147_V	0.953	0.99
176_Y	192_P	0.950	0.99
169_M	192_P	0.946	0.99
158_D	167_R	0.946	0.99
48_S	65_M	0.944	0.99
234_V	243_S	0.937	0.99
67_L	264_A	0.937	0.99
204_E	222_D	0.935	0.99
54_H	84_A	0.932	0.99
254_A	259_E	0.927	0.99
132_L	151_D	0.925	0.99
298_V	337_T	0.923	0.99
132_L	139_F	0.923	0.99
122_L	172_I	0.920	0.99
298_V	335_G	0.917	0.99
113_A	153_A	0.917	0.99
65_M	99_K	0.917	0.99
116_L	148_I	0.916	0.99
150_H	153_A	0.911	0.99
367_T	371_D	0.908	0.99
349_A	353_K	0.896	0.99
156_L	160_D	0.894	0.99
366_V	369_I	0.890	0.99
406_P	410_G	0.889	0.99
65_M	96_S	0.887	0.99
185_T	234_V	0.885	0.99
244_A	247_L	0.885	0.99
58_Q	183_D	0.884	0.98
364_Q	373_I	0.882	0.98
207_Y	238_D	0.878	0.98
252_T	257_F	0.878	0.98
299_P	322_V	0.876	0.98
364_Q	368_I	0.874	0.98
200_L	235_L	0.873	0.98
198_L	227_V	0.872	0.98
269_V	272_D	0.872	0.98
281_N	285_Q	0.872	0.98
176_Y	194_G	0.865	0.98
139_F	147_V	0.862	0.98
133_A	138_A	0.861	0.98
272_D	276_Y	0.856	0.98
236_D	243_S	0.855	0.98
123_V	173_H	0.853	0.98
228_R	246_Q	0.848	0.98
334_V	360_T	0.847	0.98
224_V	242_F	0.846	0.98
151_D	172_I	0.844	0.98
343_Q	347_E	0.843	0.98
301_P	336_R	0.842	0.98
216_I	223_V	0.842	0.98
96_S	142_D	0.842	0.98
308_A	311_Y	0.838	0.98
180_I	190_R	0.837	0.98
390_G	397_R	0.834	0.98
25_L	30_A	0.832	0.98
247_L	250_R	0.829	0.98
201_G	220_G	0.828	0.98
361_V	378_T	0.827	0.98
347_E	377_T	0.826	0.98
105_F	141_S	0.826	0.98
379_S	396_V	0.825	0.98
179_T	191_D	0.824	0.98
203_V	207_Y	0.824	0.98
156_L	184_D	0.824	0.98
177_S	195_N	0.823	0.98
298_V	327_G	0.818	0.98
224_V	240_T	0.816	0.97
327_G	354_L	0.816	0.97
156_L	164_A	0.816	0.97
338_F	355_N	0.815	0.97
295_D	361_V	0.815	0.97
131_D	134_A	0.812	0.97
243_S	249_D	0.811	0.97
40_A	218_T	0.811	0.97
21_V	210_A	0.810	0.97
62_H	76_D	0.809	0.97
63_V	100_S	0.808	0.97
148_I	168_T	0.807	0.97
185_T	236_D	0.803	0.97
159_A	167_R	0.803	0.97
344_E	348_R	0.802	0.97
354_L	358_K	0.801	0.97
337_T	349_A	0.798	0.97
207_Y	224_V	0.798	0.97
214_A	217_D	0.796	0.97
166_E	245_H	0.796	0.97
93_T	119_N	0.792	0.97
338_F	362_E	0.787	0.97
18_C	93_T	0.786	0.97
86_I	179_T	0.785	0.97
32_L	36_Y	0.784	0.97
100_S	140_T	0.783	0.97
178_L	189_V	0.782	0.97
110_K	150_H	0.778	0.97
35_Y	72_F	0.774	0.97
166_E	170_E	0.771	0.96
352_L	373_I	0.768	0.96
291_G	294_S	0.768	0.96
113_A	182_H	0.767	0.96
94_A	142_D	0.765	0.96
27_A	237_D	0.762	0.96
250_R	253_T	0.759	0.96
86_I	181_M	0.758	0.96
188_G	233_I	0.754	0.96
65_M	70_D	0.754	0.96
29_D	83_S	0.752	0.96
287_W	314_A	0.752	0.96
122_L	148_I	0.752	0.96
138_A	150_H	0.751	0.96
83_S	237_D	0.750	0.96
364_Q	371_D	0.749	0.96
252_T	259_E	0.748	0.96
226_D	390_G	0.747	0.96
49_A	89_V	0.743	0.96
208_V	219_I	0.743	0.96
243_S	246_Q	0.742	0.96
166_E	243_S	0.742	0.96
299_P	334_V	0.742	0.96
23_A	206_G	0.741	0.96
365_S	392_T	0.741	0.96
365_S	371_D	0.740	0.96
231_E	250_R	0.740	0.96
280_R	325_A	0.739	0.95
381_Q	403_I	0.739	0.95
64_G	70_D	0.738	0.95
31_A	80_L	0.733	0.95
30_A	85_A	0.733	0.95
278_V	398_I	0.732	0.95
298_V	368_I	0.730	0.95
199_V	223_V	0.728	0.95
84_A	189_V	0.727	0.95
384_D	387_R	0.724	0.95
190_R	234_V	0.722	0.95
23_A	208_V	0.720	0.95
364_Q	369_I	0.719	0.95
92_P	97_V	0.719	0.95
213_S	217_D	0.719	0.95
189_V	209_I	0.718	0.95
203_V	208_V	0.718	0.95
257_F	262_Y	0.712	0.94
34_T	53_A	0.712	0.94
139_F	151_D	0.712	0.94
53_A	60_H	0.711	0.94
252_T	255_H	0.711	0.94
299_P	330_K	0.711	0.94
245_H	248_V	0.710	0.94
115_G	181_M	0.709	0.94
297_V	334_V	0.709	0.94
167_R	171_R	0.709	0.94
47_E	92_P	0.707	0.94
96_S	100_S	0.706	0.94
191_D	227_V	0.703	0.94
353_K	372_S	0.701	0.94
107_V	113_A	0.698	0.94
107_V	110_K	0.696	0.94
372_S	376_G	0.695	0.94
29_D	81_H	0.695	0.94
84_A	187_L	0.694	0.94
296_V	334_V	0.693	0.94
295_D	334_V	0.693	0.94
305_R	309_S	0.692	0.94
257_F	260_Y	0.691	0.94
172_I	176_Y	0.686	0.93
39_Y	69_G	0.686	0.93
133_A	136_G	0.685	0.93
127_E	171_R	0.682	0.93
366_V	386_V	0.682	0.93
19_G	41_L	0.682	0.93
102_A	164_A	0.681	0.93
231_E	244_A	0.681	0.93
383_V	400_A	0.680	0.93
345_A	348_R	0.679	0.93
342_T	345_A	0.677	0.93
305_R	326_E	0.677	0.93
259_E	262_Y	0.676	0.93
232_A	243_S	0.675	0.93
166_E	247_L	0.675	0.93
294_S	332_R	0.671	0.93
291_G	397_R	0.671	0.93
368_I	396_V	0.670	0.92
94_A	121_N	0.669	0.92
181_M	189_V	0.669	0.92
300_V	337_T	0.669	0.92
155_N	159_A	0.669	0.92
165_V	169_M	0.668	0.92
179_T	235_L	0.665	0.92
365_S	368_I	0.664	0.92
188_G	191_D	0.661	0.92
19_G	49_A	0.660	0.92
277_E	281_N	0.657	0.92
39_Y	68_V	0.654	0.92
169_M	189_V	0.651	0.91
222_D	252_T	0.650	0.91
368_I	386_V	0.650	0.91
37_A	208_V	0.650	0.91
200_L	207_Y	0.649	0.91
94_A	125_A	0.649	0.91
90_R	93_T	0.649	0.91
20_V	179_T	0.648	0.91
285_Q	403_I	0.646	0.91
90_R	95_G	0.643	0.91
338_F	373_I	0.641	0.91
255_H	271_D	0.639	0.91
112_G	153_A	0.639	0.91
28_R	33_P	0.639	0.91
340_M	345_A	0.638	0.91
132_L	136_G	0.637	0.91
33_P	203_V	0.637	0.91
349_A	372_S	0.634	0.90
304_G	354_L	0.633	0.90
233_I	240_T	0.631	0.90
55_D	82_G	0.631	0.90
361_V	386_V	0.631	0.90
193_R	229_P	0.630	0.90
379_S	382_L	0.629	0.90
274_L	306_A	0.627	0.90
68_V	87_G	0.625	0.90
312_A	320_S	0.624	0.90
368_I	371_D	0.624	0.90
385_L	399_G	0.623	0.90
165_V	168_T	0.623	0.90
301_P	338_F	0.623	0.90
301_P	322_V	0.623	0.90
235_L	240_T	0.619	0.89
63_V	106_S	0.617	0.89
255_H	260_Y	0.616	0.89
274_L	277_E	0.616	0.89
127_E	130_A	0.616	0.89
182_H	190_R	0.614	0.89
154_R	158_D	0.612	0.89
367_T	397_R	0.610	0.89
111_G	157_L	0.610	0.89
93_T	118_H	0.610	0.89
64_G	68_V	0.608	0.88
139_F	146_E	0.608	0.88
290_T	293_E	0.608	0.88
270_I	275_V	0.606	0.88
152_L	164_A	0.606	0.88
302_D	306_A	0.605	0.88
22_G	186_V	0.604	0.88
366_V	371_D	0.604	0.88
369_I	374_V	0.602	0.88
185_T	190_R	0.599	0.88
305_R	324_F	0.596	0.87
370_D	374_V	0.595	0.87
105_F	143_G	0.595	0.87
34_T	86_I	0.594	0.87
288_H	384_D	0.593	0.87
227_V	231_E	0.593	0.87
229_P	353_K	0.592	0.87
276_Y	306_A	0.591	0.87
399_G	402_Q	0.590	0.87
154_R	157_L	0.590	0.87
158_D	163_D	0.590	0.87
150_H	154_R	0.589	0.87
173_H	194_G	0.589	0.87
124_N	128_L	0.584	0.86
286_L	402_Q	0.583	0.86
63_V	66_G	0.583	0.86
307_F	399_G	0.582	0.86
196_R	346_R	0.582	0.86
302_D	332_R	0.581	0.86
390_G	396_V	0.580	0.86
27_A	83_S	0.579	0.86
306_A	309_S	0.579	0.86
282_L	383_V	0.579	0.86
111_G	153_A	0.574	0.85
273_E	281_N	0.572	0.85
243_S	247_L	0.571	0.85
73_D	77_I	0.571	0.85
267_D	272_D	0.570	0.85
88_H	119_N	0.569	0.85
273_E	277_E	0.564	0.84
162_V	190_R	0.564	0.84
169_M	176_Y	0.562	0.84
62_H	78_D	0.559	0.84
188_G	235_L	0.559	0.84
226_D	271_D	0.558	0.84
107_V	112_G	0.558	0.84
97_V	101_C	0.556	0.84
43_H	212_E	0.556	0.84
54_H	57_F	0.556	0.84
365_S	404_Q	0.552	0.83
165_V	232_A	0.550	0.83
284_R	288_H	0.550	0.83
363_G	392_T	0.550	0.83
28_R	208_V	0.549	0.83
324_F	350_V	0.548	0.83
136_G	139_F	0.548	0.83
255_H	258_F	0.547	0.83
74_E	78_D	0.545	0.82
243_S	248_V	0.545	0.82
72_F	76_D	0.543	0.82
61_Q	115_G	0.542	0.82
290_T	294_S	0.541	0.82
148_I	180_I	0.541	0.82
71_A	323_E	0.540	0.82
344_E	347_E	0.540	0.82
226_D	374_V	0.539	0.82
33_P	208_V	0.539	0.82
21_V	208_V	0.537	0.81
252_T	256_C	0.537	0.81
95_G	144_D	0.536	0.81
339_I	374_V	0.536	0.81
370_D	382_L	0.536	0.81
258_F	261_V	0.535	0.81
25_L	187_L	0.532	0.81
391_A	394_V	0.532	0.81
217_D	221_G	0.531	0.81
101_C	142_D	0.531	0.81
263_F	270_I	0.531	0.81
309_S	312_A	0.531	0.81
227_V	240_T	0.531	0.81
334_V	339_I	0.531	0.81
294_S	322_V	0.530	0.81
329_M	334_V	0.530	0.81
38_L	49_A	0.530	0.81
150_H	155_N	0.528	0.80
131_D	155_N	0.527	0.80
326_E	354_L	0.526	0.80
299_P	332_R	0.525	0.80
356_P	376_G	0.525	0.80
23_A	219_I	0.524	0.80
253_T	257_F	0.523	0.80
254_A	261_V	0.522	0.80
218_T	221_G	0.522	0.80
99_K	102_A	0.521	0.79
112_G	140_T	0.520	0.79
101_C	143_G	0.519	0.79
194_G	229_P	0.519	0.79
294_S	361_V	0.518	0.79
160_D	188_G	0.517	0.79
141_S	146_E	0.513	0.78
76_D	79_A	0.513	0.78
40_A	263_F	0.513	0.78
60_H	81_H	0.513	0.78
175_S	346_R	0.512	0.78
47_E	341_P	0.512	0.78
203_V	220_G	0.512	0.78
260_Y	268_S	0.510	0.78
326_E	332_R	0.508	0.78
179_T	188_G	0.508	0.78
159_A	163_D	0.507	0.78
93_T	145_T	0.505	0.77
187_L	236_D	0.505	0.77
340_M	349_A	0.504	0.77
140_T	150_H	0.504	0.77
95_G	119_N	0.503	0.77
352_L	355_N	0.502	0.77
175_S	196_R	0.502	0.77
299_P	336_R	0.501	0.77
366_V	393_E	0.500	0.77

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
1ecfA	4	0.949	100	0.381	Contact Map
1ao0A	3	0.9184	100	0.394	Contact Map
4amvA	2	0.9347	100	0.502	Contact Map
1xffA	2	0.4776	100	0.66	Contact Map
1te5A	2	0.4408	100	0.694	Contact Map
3mdnA	4	0.4082	100	0.697	Contact Map
1ofdA	1	0.851	100	0.708	Contact Map
1ea0A	1	0.8653	100	0.713	Contact Map
4zflA	5	0.4245	100	0.729	Contact Map
1ct9A	2	0.8	100	0.733	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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