Q9HPR7 - HALSA - GREMLIN Contacts

Home
GREMLIN
- Submit - Monomer
- Submit - Complex
Contacts
Metagenomics
- Contacts
- Structures
Structures
- List
Old Projects
- Complexes (2014)
- PFAM (2013)

Q9HPR7 - Uncharacterized protein

UniProt:	Q9HPR7	Sequences: MQLTFLGTGSAMPTGQRMQTGLLVEDGDSRLLVDCGSGVLHTLARTDVGYEGVDTVLLSHHHLDHVSDLLALLKARWLAGEETLTVVGPAGTDALVTDLLGVHDYLQGRVDVTLREVDVGSVGVAGFDVTAIETEHSMPGLAYRFGGDDGDLVFSADTEAFDGMGAFADGASVLVHDCSFPDEVDVSNHPTPTQLGASLAGVDVDDLYLTHLYPHTNGEHDAMTASIHEAGFDGEVHIARDGLGVEL	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	247 (231)
Sequences:	8925 (6569)
Seq/√Len:	432.2

ECOLI - RBN PHNP
BACSU - YHFI RNZ YYCJ
HALSA - Q9HPR7 RNZ Q9HNK7
SULSO - RNZ Q981E1

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
153_V	171_A	4.632	1.00
144_R	151_D	3.526	1.00
172_S	205_D	3.351	1.00
5_F	8_T	3.159	1.00
165_G	201_G	3.109	1.00
206_D	237_H	2.833	1.00
85_T	115_R	2.734	1.00
25_E	30_R	2.666	1.00
5_F	239_A	2.324	1.00
33_V	145_F	2.270	1.00
199_L	207_L	2.249	1.00
173_V	208_Y	2.240	1.00
182_D	193_T	2.235	1.00
134_T	142_A	2.144	1.00
123_G	128_D	2.113	1.00
85_T	113_T	2.105	1.00
42_T	45_R	2.062	1.00
29_S	54_D	2.059	1.00
93_D	97_T	2.049	1.00
55_T	85_T	2.014	1.00
23_L	30_R	1.993	1.00
132_I	167_F	1.991	1.00
224_T	228_H	1.981	1.00
175_V	210_T	1.980	1.00
153_V	168_A	1.971	1.00
134_T	140_G	1.967	1.00
176_H	190_P	1.930	1.00
197_A	201_G	1.914	1.00
166_A	169_D	1.812	1.00
57_L	129_V	1.803	1.00
206_D	235_E	1.728	1.00
170_G	203_D	1.724	1.00
152_L	175_V	1.637	1.00
151_D	171_A	1.583	1.00
57_L	143_Y	1.572	1.00
194_Q	197_A	1.554	1.00
168_A	171_A	1.549	1.00
31_L	55_T	1.546	1.00
130_T	146_G	1.537	1.00
38_G	41_H	1.532	1.00
4_T	25_E	1.524	1.00
128_D	146_G	1.496	1.00
140_G	156_A	1.463	1.00
146_G	151_D	1.452	1.00
144_R	153_V	1.450	1.00
151_D	172_S	1.446	1.00
55_T	87_V	1.426	1.00
35_C	58_L	1.425	1.00
199_L	204_V	1.407	1.00
155_S	176_H	1.404	1.00
208_Y	237_H	1.403	1.00
162_D	165_G	1.397	1.00
58_L	69_L	1.392	1.00
118_D	121_S	1.386	1.00
134_T	155_S	1.377	1.00
29_S	125_A	1.371	1.00
144_R	171_A	1.364	1.00
162_D	201_G	1.361	1.00
133_E	139_P	1.334	1.00
135_E	159_E	1.333	1.00
5_F	208_Y	1.331	1.00
222_A	225_A	1.329	1.00
21_G	39_V	1.317	1.00
208_Y	239_A	1.314	1.00
26_D	126_G	1.306	1.00
88_G	93_D	1.304	1.00
31_L	127_F	1.299	1.00
8_T	17_R	1.272	1.00
89_P	141_L	1.264	1.00
169_D	203_D	1.261	1.00
90_A	116_E	1.256	1.00
225_A	228_H	1.256	1.00
20_T	154_F	1.255	1.00
178_C	209_L	1.250	1.00
83_T	113_T	1.220	1.00
39_V	43_L	1.219	1.00
165_G	169_D	1.218	1.00
65_H	211_H	1.213	1.00
193_T	197_A	1.210	1.00
5_F	175_V	1.209	1.00
95_L	99_L	1.203	1.00
59_S	143_Y	1.181	1.00
38_G	42_T	1.177	1.00
5_F	22_L	1.176	1.00
93_D	116_E	1.167	1.00
168_A	202_V	1.166	1.00
165_G	198_S	1.163	1.00
131_A	143_Y	1.155	1.00
221_D	224_T	1.152	1.00
159_E	194_Q	1.150	1.00
63_L	67_S	1.141	1.00
192_P	196_G	1.133	1.00
196_G	231_G	1.131	1.00
49_G	52_G	1.127	1.00
30_R	52_G	1.127	1.00
88_G	92_T	1.121	1.00
155_S	158_T	1.113	1.00
23_L	32_L	1.104	1.00
33_V	57_L	1.102	1.00
176_H	195_L	1.094	1.00
173_V	206_D	1.093	1.00
204_V	207_L	1.091	1.00
87_V	115_R	1.086	1.00
197_A	200_A	1.081	1.00
191_T	194_Q	1.081	1.00
158_T	164_M	1.078	1.00
57_L	122_V	1.078	1.00
3_L	22_L	1.069	1.00
142_A	155_S	1.037	1.00
129_V	145_F	1.036	1.00
178_C	195_L	1.034	1.00
54_D	82_E	1.031	1.00
123_G	126_G	1.030	1.00
83_T	111_D	1.030	1.00
56_V	69_L	1.025	1.00
147_G	150_G	1.024	1.00
30_R	54_D	1.021	1.00
150_G	172_S	1.018	1.00
163_G	166_A	1.018	1.00
8_T	241_D	1.015	1.00
132_I	164_M	1.010	1.00
221_D	225_A	1.008	1.00
41_H	45_R	1.004	1.00
22_L	210_T	1.001	1.00
210_T	239_A	1.000	1.00
26_D	29_S	1.000	1.00
90_A	94_A	0.999	1.00
119_V	133_E	0.990	1.00
23_L	48_V	0.988	1.00
32_L	39_V	0.987	1.00
3_L	152_L	0.987	1.00
37_S	40_L	0.985	1.00
161_F	164_M	0.976	1.00
18_M	41_H	0.974	1.00
29_S	126_G	0.966	1.00
3_L	173_V	0.962	1.00
98_D	101_G	0.955	1.00
178_C	192_P	0.943	1.00
70_L	74_K	0.940	1.00
24_V	145_F	0.940	1.00
17_R	241_D	0.933	1.00
94_A	101_G	0.927	1.00
197_A	231_G	0.926	1.00
29_S	124_V	0.925	1.00
61_H	91_G	0.923	1.00
3_L	24_V	0.922	1.00
6_L	21_G	0.920	1.00
137_S	188_N	0.915	1.00
32_L	35_C	0.905	1.00
169_D	201_G	0.905	1.00
130_T	167_F	0.904	1.00
162_D	166_A	0.901	1.00
29_S	127_F	0.901	1.00
35_C	39_V	0.897	1.00
224_T	238_I	0.896	1.00
94_A	97_T	0.895	1.00
176_H	198_S	0.889	1.00
212_L	238_I	0.888	1.00
164_M	167_F	0.886	1.00
159_E	190_P	0.879	1.00
193_T	230_A	0.876	1.00
26_D	127_F	0.875	1.00
31_L	129_V	0.873	1.00
171_A	204_V	0.873	1.00
24_V	33_V	0.867	1.00
222_A	226_S	0.867	1.00
146_G	149_D	0.863	1.00
94_A	98_D	0.861	1.00
181_P	192_P	0.859	1.00
18_M	45_R	0.853	1.00
117_V	143_Y	0.851	1.00
61_H	92_T	0.845	1.00
223_M	226_S	0.841	1.00
33_V	154_F	0.836	1.00
97_T	101_G	0.834	1.00
159_E	188_N	0.824	1.00
174_L	199_L	0.822	1.00
132_I	142_A	0.818	1.00
91_G	139_P	0.815	1.00
165_G	202_V	0.812	1.00
195_L	199_L	0.812	1.00
89_P	92_T	0.811	1.00
24_V	152_L	0.808	1.00
196_G	199_L	0.807	1.00
196_G	200_A	0.805	1.00
232_F	236_V	0.804	1.00
9_G	17_R	0.802	1.00
57_L	87_V	0.801	1.00
200_A	233_D	0.801	1.00
22_L	33_V	0.800	1.00
134_T	156_A	0.797	1.00
100_L	103_H	0.795	1.00
193_T	231_G	0.794	1.00
31_L	57_L	0.789	1.00
33_V	143_Y	0.785	1.00
58_L	92_T	0.778	1.00
90_A	118_D	0.773	1.00
228_H	237_H	0.769	1.00
29_S	55_T	0.769	1.00
3_L	175_V	0.765	1.00
135_E	161_F	0.764	1.00
104_D	107_Q	0.763	1.00
18_M	42_T	0.762	1.00
224_T	236_V	0.760	1.00
181_P	184_V	0.759	1.00
191_T	195_L	0.758	1.00
181_P	231_G	0.757	1.00
121_S	131_A	0.754	1.00
50_Y	72_L	0.751	1.00
155_S	164_M	0.744	1.00
91_G	116_E	0.743	1.00
179_S	213_Y	0.742	1.00
9_G	16_Q	0.741	1.00
31_L	145_F	0.739	1.00
176_H	207_L	0.737	1.00
180_F	187_S	0.736	1.00
200_A	231_G	0.724	1.00
61_H	66_V	0.722	1.00
177_D	190_P	0.720	1.00
134_T	158_T	0.718	1.00
56_V	84_L	0.718	1.00
163_G	167_F	0.716	1.00
160_A	194_Q	0.716	1.00
40_L	44_A	0.712	1.00
22_L	154_F	0.709	1.00
55_T	124_V	0.708	1.00
99_L	102_V	0.707	1.00
93_D	114_L	0.706	1.00
154_F	210_T	0.704	1.00
42_T	46_T	0.703	1.00
22_L	175_V	0.701	1.00
227_I	232_F	0.700	1.00
212_L	216_T	0.698	1.00
154_F	175_V	0.695	1.00
161_F	165_G	0.694	1.00
144_R	167_F	0.692	1.00
35_C	56_V	0.691	1.00
193_T	226_S	0.691	1.00
76_R	80_G	0.687	1.00
223_M	227_I	0.680	1.00
70_L	99_L	0.680	1.00
153_V	174_L	0.678	1.00
31_L	124_V	0.677	1.00
117_V	141_L	0.675	1.00
117_V	131_A	0.675	1.00
56_V	72_L	0.669	1.00
92_T	99_L	0.669	1.00
43_L	50_Y	0.666	1.00
113_T	116_E	0.664	1.00
152_L	173_V	0.664	1.00
21_G	32_L	0.659	1.00
19_Q	37_S	0.655	0.99
168_A	174_L	0.653	0.99
37_S	42_T	0.652	0.99
69_L	86_V	0.652	0.99
130_T	144_R	0.651	0.99
73_L	84_L	0.649	0.99
37_S	71_A	0.649	0.99
132_I	168_A	0.644	0.99
209_L	212_L	0.639	0.99
192_P	216_T	0.637	0.99
225_A	230_A	0.637	0.99
155_S	174_L	0.636	0.99
32_L	53_V	0.632	0.99
199_L	209_L	0.631	0.99
33_V	59_S	0.629	0.99
59_S	154_F	0.628	0.99
58_L	96_V	0.624	0.99
129_V	143_Y	0.624	0.99
132_I	144_R	0.623	0.99
48_V	52_G	0.622	0.99
174_L	204_V	0.622	0.99
135_E	188_N	0.617	0.99
142_A	153_V	0.615	0.99
40_L	71_A	0.614	0.99
209_L	236_V	0.614	0.99
10_S	179_S	0.613	0.99
160_A	197_A	0.610	0.99
37_S	68_D	0.606	0.99
26_D	147_G	0.605	0.99
62_H	136_H	0.605	0.99
190_P	198_S	0.604	0.99
233_D	236_V	0.604	0.99
54_D	125_A	0.601	0.99
155_S	177_D	0.596	0.99
227_I	236_V	0.593	0.99
4_T	46_T	0.592	0.99
232_F	235_E	0.591	0.99
196_G	227_I	0.590	0.99
195_L	207_L	0.589	0.99
199_L	202_V	0.588	0.99
158_T	190_P	0.587	0.99
131_A	141_L	0.586	0.99
195_L	204_V	0.586	0.99
198_S	202_V	0.585	0.99
61_H	95_L	0.581	0.99
30_R	48_V	0.581	0.99
20_T	210_T	0.577	0.99
127_F	145_F	0.576	0.99
96_V	99_L	0.572	0.99
181_P	223_M	0.572	0.99
95_L	98_D	0.568	0.99
9_G	14_T	0.567	0.99
60_H	65_H	0.566	0.99
60_H	64_D	0.565	0.98
61_H	89_P	0.563	0.98
62_H	65_H	0.563	0.98
199_L	203_D	0.562	0.98
76_R	82_E	0.559	0.98
96_V	100_L	0.558	0.98
119_V	141_L	0.557	0.98
17_R	21_G	0.555	0.98
96_V	103_H	0.555	0.98
171_A	174_L	0.555	0.98
15_G	217_N	0.551	0.98
21_G	35_C	0.544	0.98
142_A	158_T	0.540	0.98
87_V	117_V	0.540	0.98
178_C	191_T	0.539	0.98
170_G	205_D	0.535	0.98
135_E	158_T	0.534	0.98
43_L	53_V	0.533	0.98
19_Q	22_L	0.531	0.98
177_D	189_H	0.530	0.98
4_T	23_L	0.527	0.98
25_E	28_D	0.526	0.98
182_D	185_D	0.524	0.98
174_L	207_L	0.524	0.98
156_A	211_H	0.522	0.97
192_P	227_I	0.519	0.97
226_S	230_A	0.516	0.97
228_H	236_V	0.516	0.97
153_V	167_F	0.516	0.97
37_S	41_H	0.514	0.97
10_S	19_Q	0.510	0.97
196_G	236_V	0.509	0.97
25_E	48_V	0.509	0.97
155_S	168_A	0.509	0.97
89_P	139_P	0.508	0.97
209_L	227_I	0.506	0.97
89_P	133_E	0.505	0.97
199_L	227_I	0.505	0.97
180_F	191_T	0.501	0.97
158_T	177_D	0.500	0.97
95_L	103_H	0.500	0.97
76_R	84_L	0.500	0.97

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
3zwfA	2	0.9271	100	0.208	Contact Map
2cbnA	2	0.9879	100	0.244	Contact Map
1y44A	2	0.9879	100	0.25	Contact Map
1zkpA	2	0.9555	100	0.323	Contact Map
3jxpA	2	0.9595	100	0.346	Contact Map
3g1pA	2	0.915	100	0.375	Contact Map
2e7yA	2	0.9312	100	0.376	Contact Map
4ojvA	2	0.9879	100	0.38	Contact Map
3md7A	2	0.9352	100	0.384	Contact Map
3bk2A	2	0.9433	100	0.485	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.0089 seconds.