HMAT - HALSA - GREMLIN Contacts

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HMAT - Heme-based aerotactic transducer HemAT

UniProt:	Q9HPR6	Sequences: MSNDNDTLVTADVRNGIDGHALADRIGLDEAEIAWRLSFTGIDDDTMAALAAEQPLFEATADALVTDFYDHLESYERTQDLFANSTKTVEQLKETQAEYLLGLGRGEYDTEYAAQRARIGKIHDVLGLGPDVYLGAYTRYYTGLLDALADDVVADRGEEAAAAVDELVARFLPMLKLLTFDQQIAMDTYIDSYAQRLHDEIDSRQELANAVASDVEAPLSSLEATSQDVAERTDTMRAATDDQVDRMADVSREISSVSASVEEVASTADDVRRTSEDAEALAQQGEAAADDALATMTDIDEATDGVTAGVEQLRERAADVESVTGVIDDIAEQTNMLALNASIEAARAGEAGEGFAVVADEVKALAEESREQSTRVEELVEQMQAETEETVDQLDEVNQRIGEGVERVEEAMETLQEITDAVEDAASGMQEVSTATDEQAVSTEEVAEMVDDVDDRAGEIAAALDDIADATDQQVRTVEEVRETVGKLS	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	489 (438)
Sequences:	16273 (13473)
Seq/√Len:	643.8

ECOLI - MCP4 MCP3 MCP2 MCP1 AER
BACSU - YVAQ YOAH MCPC MCPB TLPB TLPA MCPA TLPC HEMAT YFMS
HALSA - HMAT Q9HQX8 HTR7 Q9HPA2 HTR9 HTR2 HTR4 Q9HRA1 Q9HP10 COST Q9HS86 Q9HR88 Q9HRN6 Q9HQT5 Q9HPQ5 HTR1 Q9HPW6

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
197_L	202_D	3.919	1.00
183_Q	188_T	3.142	1.00
183_Q	191_D	2.558	1.00
69_Y	86_T	2.448	1.00
312_Q	386_E	2.373	1.00
192_S	216_E	2.297	1.00
315_E	318_A	2.218	1.00
209_N	212_A	2.194	1.00
168_V	172_L	2.166	1.00
182_Q	203_S	2.153	1.00
178_L	203_S	2.125	1.00
316_R	382_Q	2.107	1.00
178_L	207_L	2.102	1.00
177_L	205_Q	2.099	1.00
146_D	150_D	2.071	1.00
316_R	386_E	2.070	1.00
182_Q	210_A	1.965	1.00
167_L	171_F	1.947	1.00
199_D	202_D	1.918	1.00
319_D	322_S	1.907	1.00
325_G	329_D	1.903	1.00
302_A	396_E	1.899	1.00
59_A	63_A	1.887	1.00
263_E	266_S	1.879	1.00
182_Q	186_M	1.858	1.00
287_A	291_D	1.843	1.00
284_Q	287_A	1.839	1.00
143_G	147_A	1.836	1.00
124_D	128_L	1.818	1.00
409_E	413_E	1.807	1.00
181_D	208_A	1.802	1.00
149_A	153_V	1.797	1.00
128_L	132_V	1.793	1.00
410_E	413_E	1.769	1.00
209_N	213_S	1.753	1.00
388_E	392_D	1.749	1.00
299_I	404_G	1.737	1.00
310_V	390_T	1.733	1.00
301_E	305_G	1.719	1.00
273_R	276_E	1.704	1.00
192_S	209_N	1.687	1.00
322_S	325_G	1.677	1.00
181_D	211_V	1.663	1.00
245_D	248_A	1.660	1.00
192_S	213_S	1.659	1.00
277_D	280_A	1.644	1.00
80_D	84_N	1.641	1.00
62_D	66_T	1.621	1.00
293_L	412_M	1.618	1.00
117_A	121_K	1.618	1.00
243_Q	250_V	1.613	1.00
184_I	212_A	1.611	1.00
395_D	399_Q	1.607	1.00
311_E	395_D	1.606	1.00
402_G	406_E	1.601	1.00
314_R	391_V	1.597	1.00
145_L	149_A	1.595	1.00
83_A	87_K	1.594	1.00
97_A	101_L	1.589	1.00
79_Q	83_A	1.578	1.00
466_D	469_D	1.576	1.00
399_Q	403_E	1.573	1.00
184_I	211_V	1.572	1.00
131_D	135_G	1.570	1.00
308_A	312_Q	1.569	1.00
309_G	389_E	1.566	1.00
182_Q	207_L	1.563	1.00
84_N	88_T	1.562	1.00
203_S	206_E	1.557	1.00
321_E	384_Q	1.555	1.00
216_E	220_S	1.546	1.00
377_E	381_E	1.542	1.00
392_D	396_E	1.536	1.00
150_D	154_A	1.526	1.00
181_D	207_L	1.519	1.00
120_G	124_D	1.512	1.00
309_G	390_T	1.512	1.00
106_G	110_T	1.507	1.00
163_A	167_L	1.506	1.00
101_L	105_R	1.505	1.00
369_S	373_S	1.502	1.00
192_S	212_A	1.500	1.00
142_T	146_D	1.497	1.00
280_A	284_Q	1.489	1.00
217_A	221_S	1.487	1.00
177_L	208_A	1.481	1.00
60_T	63_A	1.478	1.00
141_Y	145_L	1.476	1.00
364_A	367_E	1.470	1.00
406_E	410_E	1.464	1.00
316_R	319_D	1.461	1.00
76_E	79_Q	1.458	1.00
90_E	94_E	1.456	1.00
262_E	266_S	1.455	1.00
77_R	80_D	1.444	1.00
146_D	149_A	1.442	1.00
311_E	315_E	1.435	1.00
367_E	371_E	1.434	1.00
55_P	59_A	1.428	1.00
273_R	277_D	1.426	1.00
465_D	469_D	1.425	1.00
188_T	191_D	1.425	1.00
51_A	104_G	1.422	1.00
177_L	204_R	1.421	1.00
312_Q	315_E	1.417	1.00
371_E	375_R	1.415	1.00
459_E	462_A	1.406	1.00
473_Q	476_R	1.401	1.00
221_S	480_E	1.401	1.00
98_E	101_L	1.401	1.00
63_A	67_D	1.400	1.00
276_E	280_A	1.399	1.00
142_T	145_L	1.398	1.00
445_E	448_E	1.392	1.00
305_G	308_A	1.386	1.00
399_Q	402_G	1.385	1.00
175_L	178_L	1.378	1.00
319_D	375_R	1.376	1.00
52_A	56_L	1.374	1.00
83_A	86_T	1.373	1.00
304_D	308_A	1.371	1.00
48_A	52_A	1.369	1.00
308_A	311_E	1.364	1.00
195_Q	209_N	1.363	1.00
86_T	90_E	1.357	1.00
342_S	360_D	1.348	1.00
302_A	400_R	1.348	1.00
236_M	240_T	1.345	1.00
269_D	273_R	1.345	1.00
403_E	406_E	1.338	1.00
261_V	264_V	1.337	1.00
317_A	387_T	1.335	1.00
328_D	377_E	1.330	1.00
108_Y	112_Y	1.316	1.00
301_E	304_D	1.315	1.00
310_V	394_L	1.312	1.00
75_Y	78_T	1.310	1.00
413_E	417_E	1.307	1.00
315_E	319_D	1.307	1.00
51_A	55_P	1.307	1.00
135_G	139_R	1.300	1.00
462_A	465_D	1.299	1.00
401_I	404_G	1.296	1.00
360_D	363_K	1.291	1.00
438_E	441_V	1.291	1.00
252_R	256_S	1.291	1.00
374_T	378_E	1.286	1.00
458_G	462_A	1.284	1.00
451_D	455_D	1.283	1.00
126_L	129_G	1.279	1.00
178_L	182_Q	1.276	1.00
118_R	121_K	1.271	1.00
462_A	466_D	1.270	1.00
231_E	235_T	1.268	1.00
270_D	273_R	1.268	1.00
417_E	420_D	1.266	1.00
176_K	194_A	1.265	1.00
423_E	427_S	1.261	1.00
326_V	372_Q	1.254	1.00
298_D	400_R	1.248	1.00
283_Q	287_A	1.245	1.00
314_R	388_E	1.244	1.00
291_D	294_A	1.241	1.00
214_D	217_A	1.239	1.00
306_V	394_L	1.232	1.00
309_G	393_Q	1.231	1.00
113_A	117_A	1.231	1.00
281_L	417_E	1.229	1.00
256_S	259_A	1.226	1.00
455_D	459_E	1.224	1.00
107_E	110_T	1.219	1.00
318_A	388_E	1.214	1.00
476_R	480_E	1.214	1.00
249_D	252_R	1.206	1.00
392_D	395_D	1.204	1.00
223_E	227_Q	1.204	1.00
300_D	405_V	1.204	1.00
84_N	87_K	1.203	1.00
114_A	117_A	1.198	1.00
58_E	62_D	1.195	1.00
381_E	385_A	1.189	1.00
109_D	113_A	1.186	1.00
159_E	163_A	1.184	1.00
94_E	98_E	1.183	1.00
444_E	448_E	1.180	1.00
482_R	486_G	1.178	1.00
271_V	429_M	1.176	1.00
280_A	283_Q	1.174	1.00
396_E	399_Q	1.172	1.00
319_D	382_Q	1.160	1.00
179_T	182_Q	1.159	1.00
282_A	419_T	1.156	1.00
307_T	398_N	1.150	1.00
76_E	80_D	1.150	1.00
95_T	98_E	1.146	1.00
161_A	165_D	1.146	1.00
224_A	227_Q	1.143	1.00
279_E	283_Q	1.140	1.00
213_S	217_A	1.139	1.00
98_E	102_G	1.136	1.00
238_A	242_D	1.131	1.00
306_V	397_V	1.129	1.00
452_D	455_D	1.128	1.00
87_K	91_Q	1.122	1.00
342_S	363_K	1.109	1.00
290_D	294_A	1.106	1.00
245_D	249_D	1.106	1.00
68_F	78_T	1.102	1.00
56_L	60_T	1.098	1.00
186_M	210_A	1.097	1.00
310_V	391_V	1.096	1.00
174_M	201_I	1.094	1.00
314_R	318_A	1.093	1.00
371_E	374_T	1.093	1.00
176_K	179_T	1.092	1.00
297_T	301_E	1.092	1.00
291_D	407_R	1.091	1.00
441_V	445_E	1.089	1.00
455_D	458_G	1.088	1.00
385_A	389_E	1.081	1.00
431_E	434_T	1.079	1.00
125_V	128_L	1.079	1.00
177_L	181_D	1.079	1.00
180_F	193_Y	1.077	1.00
224_A	228_D	1.077	1.00
241_D	245_D	1.071	1.00
77_R	81_L	1.066	1.00
195_Q	205_Q	1.062	1.00
259_A	263_E	1.061	1.00
164_V	168_V	1.057	1.00
328_D	373_S	1.056	1.00
472_D	476_R	1.049	1.00
170_R	173_P	1.049	1.00
193_Y	209_N	1.049	1.00
246_R	452_D	1.049	1.00
424_D	427_S	1.047	1.00
305_G	396_E	1.046	1.00
129_G	132_V	1.046	1.00
121_K	124_D	1.044	1.00
413_E	416_Q	1.044	1.00
243_Q	246_R	1.041	1.00
378_E	382_Q	1.041	1.00
64_L	67_D	1.041	1.00
52_A	55_P	1.040	1.00
134_L	138_T	1.035	1.00
92_L	96_Q	1.033	1.00
212_A	216_E	1.031	1.00
94_E	97_A	1.031	1.00
313_L	390_T	1.030	1.00
236_M	239_A	1.029	1.00
89_V	93_K	1.028	1.00
430_Q	434_T	1.028	1.00
132_V	136_A	1.028	1.00
227_Q	231_E	1.027	1.00
253_E	256_S	1.027	1.00
286_E	290_D	1.024	1.00
480_E	483_E	1.021	1.00
437_D	441_V	1.019	1.00
456_R	460_I	1.017	1.00
139_R	143_G	1.016	1.00
129_G	133_Y	1.016	1.00
114_A	118_R	1.016	1.00
206_E	209_N	1.015	1.00
176_K	180_F	1.015	1.00
416_Q	420_D	1.013	1.00
101_L	104_G	1.013	1.00
50_L	54_Q	1.012	1.00
195_Q	206_E	1.011	1.00
56_L	59_A	1.011	1.00
374_T	377_E	1.008	1.00
173_P	200_E	1.008	1.00
80_D	83_A	1.004	1.00
178_L	204_R	1.004	1.00
88_T	118_R	1.004	1.00
175_L	179_T	1.003	1.00
155_D	159_E	1.000	1.00
469_D	473_Q	0.999	1.00
98_E	107_E	0.996	1.00
147_A	150_D	0.996	1.00
303_T	401_I	0.995	1.00
57_F	61_A	0.993	1.00
179_T	183_Q	0.992	1.00
58_E	97_A	0.992	1.00
183_Q	186_M	0.992	1.00
126_L	133_Y	0.991	1.00
294_A	297_T	0.984	1.00
382_Q	386_E	0.984	1.00
286_E	416_Q	0.982	1.00
479_E	483_E	0.981	1.00
61_A	65_V	0.981	1.00
153_V	157_G	0.980	1.00
93_K	97_A	0.979	1.00
448_E	451_D	0.974	1.00
63_A	66_T	0.972	1.00
304_D	402_G	0.971	1.00
87_K	90_E	0.970	1.00
120_G	123_H	0.968	1.00
294_A	298_D	0.968	1.00
53_E	56_L	0.967	1.00
292_A	404_G	0.966	1.00
173_P	197_L	0.965	1.00
205_Q	209_N	0.961	1.00
434_T	438_E	0.961	1.00
88_T	91_Q	0.960	1.00
122_I	126_L	0.957	1.00
121_K	125_V	0.955	1.00
138_T	142_T	0.955	1.00
62_D	93_K	0.955	1.00
323_V	379_L	0.954	1.00
210_A	213_S	0.953	1.00
169_A	173_P	0.950	1.00
49_A	52_A	0.950	1.00
127_G	131_D	0.950	1.00
54_Q	58_E	0.949	1.00
287_A	290_D	0.948	1.00
252_R	259_A	0.947	1.00
313_L	383_M	0.945	1.00
370_R	374_T	0.941	1.00
181_D	204_R	0.935	1.00
266_S	270_D	0.935	1.00
368_E	375_R	0.934	1.00
375_R	378_E	0.931	1.00
420_D	424_D	0.931	1.00
160_A	164_V	0.930	1.00
111_E	114_A	0.927	1.00
299_I	401_I	0.927	1.00
174_M	204_R	0.927	1.00
255_S	259_A	0.925	1.00
66_T	69_Y	0.925	1.00
221_S	484_T	0.923	1.00
81_L	84_N	0.921	1.00
165_D	168_V	0.915	1.00
47_M	51_A	0.915	1.00
60_T	64_L	0.915	1.00
193_Y	205_Q	0.913	1.00
296_M	404_G	0.912	1.00
100_L	104_G	0.904	1.00
194_A	209_N	0.901	1.00
291_D	410_E	0.900	1.00
448_E	452_D	0.897	1.00
427_S	430_Q	0.891	1.00
130_P	133_Y	0.889	1.00
235_T	238_A	0.887	1.00
172_L	176_K	0.885	1.00
288_A	410_E	0.885	1.00
210_A	214_D	0.884	1.00
123_H	126_L	0.883	1.00
184_I	208_A	0.882	1.00
54_Q	57_F	0.881	1.00
378_E	381_E	0.880	1.00
250_V	253_E	0.880	1.00
201_I	205_Q	0.880	1.00
302_A	305_G	0.879	1.00
109_D	112_Y	0.875	1.00
305_G	393_Q	0.875	1.00
389_E	392_D	0.873	1.00
133_Y	136_A	0.871	1.00
463_A	466_D	0.870	1.00
469_D	472_D	0.869	1.00
406_E	409_E	0.866	1.00
454_D	458_G	0.866	1.00
311_E	314_R	0.865	1.00
434_T	437_D	0.863	1.00
474_Q	478_V	0.863	1.00
312_Q	389_E	0.862	1.00
48_A	51_A	0.862	1.00
243_Q	247_M	0.857	1.00
53_E	57_F	0.856	1.00
128_L	131_D	0.854	1.00
220_S	224_A	0.854	1.00
58_E	93_K	0.854	1.00
91_Q	95_T	0.851	1.00
180_F	191_D	0.845	1.00
382_Q	385_A	0.845	1.00
137_Y	141_Y	0.844	1.00
112_Y	116_R	0.843	1.00
78_T	81_L	0.843	1.00
183_Q	211_V	0.842	1.00
65_V	69_Y	0.839	1.00
474_Q	481_V	0.836	1.00
319_D	379_L	0.832	1.00
191_D	212_A	0.832	1.00
242_D	245_D	0.827	1.00
306_V	393_Q	0.826	1.00
304_D	398_N	0.825	1.00
460_I	474_Q	0.824	1.00
300_D	304_D	0.819	1.00
195_Q	202_D	0.819	1.00
59_A	62_D	0.816	1.00
282_A	285_G	0.814	1.00
180_F	183_Q	0.814	1.00
100_L	103_L	0.813	1.00
110_T	114_A	0.812	1.00
215_V	219_L	0.812	1.00
234_D	238_A	0.810	1.00
291_D	403_E	0.810	1.00
328_D	332_E	0.809	1.00
47_M	50_L	0.806	1.00
312_Q	316_R	0.803	1.00
281_L	284_Q	0.803	1.00
147_A	151_D	0.803	1.00
50_L	57_F	0.802	1.00
136_A	140_Y	0.802	1.00
96_Q	100_L	0.800	1.00
91_Q	94_E	0.800	1.00
483_E	486_G	0.799	1.00
57_F	65_V	0.797	1.00
297_T	409_E	0.797	1.00
307_T	395_D	0.796	1.00
329_D	368_E	0.796	1.00
445_E	449_M	0.796	1.00
298_D	301_E	0.794	1.00
180_F	208_A	0.794	1.00
295_T	403_E	0.791	1.00
171_F	175_L	0.790	1.00
424_D	428_G	0.789	1.00
198_H	202_D	0.782	1.00
62_D	65_V	0.777	1.00
61_A	64_L	0.776	1.00
247_M	251_S	0.775	1.00
138_T	141_Y	0.775	1.00
329_D	332_E	0.770	1.00
173_P	201_I	0.769	1.00
175_L	203_S	0.768	1.00
318_A	322_S	0.767	1.00
238_A	241_D	0.764	1.00
447_A	451_D	0.761	1.00
366_A	369_S	0.760	1.00
266_S	269_D	0.757	1.00
197_L	200_E	0.756	1.00
85_S	115_Q	0.753	1.00
324_T	377_E	0.751	1.00
58_E	96_Q	0.749	1.00
131_D	134_L	0.744	1.00
284_Q	288_A	0.744	1.00
292_A	411_A	0.743	1.00
317_A	383_M	0.742	1.00
427_S	431_E	0.741	1.00
157_G	161_A	0.740	1.00
57_F	60_T	0.739	1.00
476_R	479_E	0.736	1.00
252_R	255_S	0.735	1.00
115_Q	122_I	0.732	1.00
117_A	120_G	0.732	1.00
407_R	410_E	0.731	1.00
387_T	390_T	0.730	1.00
323_V	380_V	0.730	1.00
278_A	422_V	0.730	1.00
208_A	211_V	0.729	1.00
474_Q	485_V	0.728	1.00
303_T	397_V	0.727	1.00
181_D	184_I	0.727	1.00
96_Q	99_Y	0.727	1.00
65_V	68_F	0.724	1.00
55_P	58_E	0.722	1.00
171_F	201_I	0.720	1.00
285_G	415_L	0.718	1.00
69_Y	83_A	0.716	1.00
368_E	371_E	0.714	1.00
221_S	224_A	0.714	1.00
140_Y	144_L	0.713	1.00
143_G	146_D	0.711	1.00
479_E	482_R	0.707	1.00
303_T	394_L	0.707	1.00
191_D	195_Q	0.707	1.00
286_E	412_M	0.706	1.00
135_G	138_T	0.705	1.00
271_V	422_V	0.700	1.00
233_T	471_T	0.699	1.00
409_E	412_M	0.698	1.00
115_Q	119_I	0.697	1.00
126_L	130_P	0.697	1.00
208_A	212_A	0.696	1.00
265_A	268_A	0.695	1.00
400_R	403_E	0.694	1.00
81_L	125_V	0.691	1.00
102_G	105_R	0.691	1.00
222_L	485_V	0.691	1.00
54_Q	61_A	0.686	1.00
447_A	450_V	0.685	1.00
78_T	126_L	0.680	1.00
307_T	311_E	0.680	1.00
481_V	485_V	0.679	1.00
220_S	223_E	0.678	1.00
215_V	218_P	0.678	1.00
49_A	53_E	0.675	1.00
248_A	252_R	0.674	1.00
51_A	54_Q	0.674	1.00
397_V	404_G	0.673	1.00
419_T	423_E	0.671	1.00
58_E	61_A	0.670	1.00
84_N	118_R	0.668	1.00
412_M	416_Q	0.666	1.00
323_V	372_Q	0.666	1.00
189_Y	215_V	0.664	1.00
274_T	424_D	0.664	1.00
85_S	89_V	0.662	1.00
441_V	444_E	0.658	1.00
67_D	71_H	0.656	1.00
50_L	53_E	0.656	1.00
279_E	423_E	0.656	1.00
385_A	388_E	0.654	1.00
439_Q	446_V	0.650	1.00
255_S	447_A	0.648	1.00
185_A	210_A	0.647	1.00
61_A	89_V	0.645	1.00
180_F	205_Q	0.645	1.00
397_V	401_I	0.644	1.00
305_G	309_G	0.644	1.00
186_M	214_D	0.643	1.00
116_R	120_G	0.642	1.00
322_S	326_V	0.641	1.00
420_D	423_E	0.641	1.00
320_V	380_V	0.640	1.00
65_V	86_T	0.640	1.00
284_Q	410_E	0.640	1.00
251_S	256_S	0.637	1.00
296_M	405_V	0.636	1.00
288_A	291_D	0.634	1.00
150_D	153_V	0.634	1.00
237_R	241_D	0.634	1.00
384_Q	388_E	0.633	1.00
119_I	122_I	0.630	1.00
115_Q	118_R	0.626	1.00
64_L	68_F	0.624	1.00
184_I	189_Y	0.623	1.00
243_Q	257_V	0.623	1.00
219_L	222_L	0.622	1.00
246_R	249_D	0.622	1.00
226_S	230_A	0.622	1.00
68_F	126_L	0.621	1.00
49_A	54_Q	0.620	1.00
257_V	260_S	0.617	1.00
69_Y	82_F	0.617	1.00
78_T	125_V	0.616	1.00
123_H	127_G	0.616	1.00
309_G	386_E	0.615	1.00
127_G	130_P	0.614	1.00
172_L	175_L	0.611	1.00
335_N	363_K	0.611	1.00
442_S	446_V	0.608	1.00
296_M	299_I	0.608	1.00
161_A	164_V	0.608	1.00
462_A	469_D	0.605	1.00
211_V	214_D	0.603	1.00
295_T	407_R	0.601	1.00
228_D	231_E	0.600	1.00
96_Q	103_L	0.600	1.00
99_Y	103_L	0.600	1.00
118_R	122_I	0.599	1.00
178_L	201_I	0.598	1.00
324_T	328_D	0.592	1.00
360_D	364_A	0.592	1.00
185_A	207_L	0.590	1.00
229_V	233_T	0.590	1.00
95_T	108_Y	0.590	1.00
322_S	375_R	0.590	1.00
227_Q	482_R	0.589	1.00
276_E	279_E	0.588	1.00
89_V	115_Q	0.586	1.00
300_D	402_G	0.585	1.00
444_E	447_A	0.585	1.00
68_F	82_F	0.585	1.00
302_A	393_Q	0.584	1.00
440_A	443_T	0.584	1.00
108_Y	116_R	0.584	1.00
92_L	112_Y	0.584	1.00
110_T	113_A	0.582	1.00
239_A	456_R	0.582	1.00
398_N	402_G	0.581	1.00
230_A	235_T	0.578	1.00
467_I	470_A	0.577	1.00
124_D	127_G	0.576	1.00
90_E	93_K	0.576	1.00
211_V	215_V	0.576	1.00
108_Y	115_Q	0.576	1.00
75_Y	125_V	0.574	1.00
82_F	86_T	0.573	1.00
130_P	134_L	0.573	1.00
243_Q	264_V	0.572	1.00
338_A	363_K	0.572	1.00
180_F	184_I	0.572	1.00
390_T	397_V	0.566	1.00
363_K	367_E	0.566	1.00
231_E	234_D	0.565	1.00
381_E	384_Q	0.564	1.00
270_D	428_G	0.564	1.00
187_D	211_V	0.563	1.00
272_R	276_E	0.563	1.00
107_E	111_E	0.562	1.00
204_R	208_A	0.562	1.00
478_V	481_V	0.561	1.00
351_A	362_V	0.560	1.00
47_M	103_L	0.559	1.00
92_L	115_Q	0.559	1.00
75_Y	79_Q	0.554	1.00
145_L	148_L	0.554	1.00
184_I	215_V	0.554	1.00
244_V	247_M	0.553	1.00
134_L	137_Y	0.553	1.00
218_P	222_L	0.552	1.00
332_E	370_R	0.551	1.00
136_A	139_R	0.549	1.00
109_D	116_R	0.547	1.00
88_T	114_A	0.547	1.00
303_T	306_V	0.545	1.00
128_L	133_Y	0.541	1.00
256_S	260_S	0.541	1.00
112_Y	115_Q	0.540	1.00
438_E	442_S	0.539	1.00
82_F	85_S	0.538	1.00
81_L	121_K	0.538	1.00
247_M	254_I	0.534	0.99
292_A	299_I	0.534	0.99
187_D	204_R	0.533	0.99
202_D	206_E	0.533	0.99
339_L	347_R	0.530	0.99
250_V	264_V	0.529	0.99
257_V	443_T	0.528	0.99
411_A	414_T	0.528	0.99
458_G	461_A	0.528	0.99
477_T	480_E	0.526	0.99
236_M	242_D	0.525	0.99
230_A	234_D	0.525	0.99
468_A	472_D	0.525	0.99
205_Q	208_A	0.525	0.99
259_A	262_E	0.523	0.99
328_D	374_T	0.523	0.99
204_R	207_L	0.523	0.99
274_T	277_D	0.522	0.99
307_T	394_L	0.522	0.99
271_V	275_S	0.522	0.99
89_V	92_L	0.519	0.99
217_A	220_S	0.519	0.99
275_S	278_A	0.518	0.99
254_I	450_V	0.516	0.99
480_E	484_T	0.516	0.99
113_A	116_R	0.515	0.99
284_Q	417_E	0.513	0.99
258_S	261_V	0.512	0.99
400_R	404_G	0.511	0.99
171_F	178_L	0.511	0.99
446_V	450_V	0.511	0.99
218_P	221_S	0.510	0.99
108_Y	111_E	0.508	0.99
84_N	121_K	0.507	0.99
380_V	384_Q	0.506	0.99
293_L	297_T	0.506	0.99
275_S	279_E	0.505	0.99
387_T	391_V	0.504	0.99
475_V	479_E	0.504	0.99
277_D	281_L	0.504	0.99
173_P	202_D	0.504	0.99
91_Q	111_E	0.503	0.99
390_T	393_Q	0.502	0.99
71_H	74_S	0.501	0.99
257_V	264_V	0.500	0.99

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
3zx6A	2	0.6155	100	0.335	Contact Map
2ch7A	2	0.6033	100	0.48	Contact Map
1qu7A	2	0.456	100	0.485	Contact Map
3g67A	2	0.4274	100	0.551	Contact Map
4i3mA	2	0.3006	99.9	0.718	Contact Map
2f95B	2	0.1084	99.3	0.841	Contact Map
4cq4A	4	0.1759	99.1	0.853	Contact Map
4gycB	2	0.1227	99.1	0.855	Contact Map
3zccA	2	0.2229	98.8	0.868	Contact Map
4i5sA	2	0.5767	98.5	0.881	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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