Q9HPQ1 - HALSA - GREMLIN Contacts

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Q9HPQ1 - Transporter

UniProt:	Q9HPQ1	Sequences: MARDVWHSRLGFIMAAVGSAVGLGNLWRFPWMTSENGGAAFLLVYLGVVLCVGVPGLLAEFVIGRRSRRSPVGAFSSLSDSTLWRVFGHLSVVIAVVLLSFYSVVGGWILRYFGASLTGAYFSNPGQYFATVSYGLDAVGFHLLFLAITGLIVVRGIKRGIENATKLMMPAVVVLLIVLAAWASTLDGAGAGLAFYLSPDVELLEADLLGILPAAAGQALFTLSLGSGTMITYASYLDEERSLAADGAAIAVLNTCIGVLAGLVVFPLLFALVGDAGTGGPGALFVGLANAFVAVPYGRAVGAVFFAVVSLAAISSSISMLELPVSFLVDEYGVSRRRATALFVGVFTVTGSATALSPGLFDFVAGTLVDLLMTAGLIGFLLFTGWVVGQNAVTEYELGAGAVASALSTPWLYAVGVVIPVFLIFTLVSGIAAALGVSITAVELWGVTISQPRLFAGLSVVIAVVSFLGLRRPASVA	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	477 (420)
Sequences:	4658 (3051)
Seq/√Len:	148.9

BACSU - YHDH YOCR
HALSA - Q9HPQ1 Q9HPQ2 Q9HHR9

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
194_A	198_S	4.382	1.00
191_A	194_A	4.074	1.00
150_G	344_V	3.883	1.00
200_D	203_L	3.751	1.00
297_Y	300_A	3.513	1.00
67_S	74_A	3.036	1.00
133_S	136_L	3.011	1.00
132_V	135_G	2.965	1.00
322_E	336_R	2.893	1.00
113_F	303_A	2.880	1.00
143_L	348_T	2.847	1.00
203_L	206_A	2.836	1.00
63_I	74_A	2.801	1.00
335_S	338_R	2.754	1.00
113_F	307_A	2.744	1.00
284_L	309_V	2.738	1.00
193_L	263_L	2.695	1.00
69_R	77_S	2.613	1.00
239_E	398_L	2.605	1.00
57_L	230_M	2.563	1.00
197_L	263_L	2.529	1.00
76_S	85_R	2.488	1.00
135_G	138_A	2.472	1.00
182_W	185_T	2.376	1.00
149_T	317_S	2.331	1.00
68_R	239_E	2.298	1.00
184_S	193_L	2.281	1.00
126_G	129_F	2.221	1.00
182_W	301_V	2.155	1.00
134_Y	138_A	2.140	1.00
428_V	432_A	2.120	1.00
28_R	218_Q	2.099	1.00
159_R	163_N	2.086	1.00
25_N	254_N	2.066	1.00
389_G	392_A	2.048	1.00
173_V	257_I	2.047	1.00
17_V	253_L	2.013	1.00
177_I	181_A	2.004	1.00
177_I	260_L	2.003	1.00
196_Y	262_G	1.974	1.00
111_R	115_A	1.963	1.00
190_G	193_L	1.957	1.00
109_I	310_S	1.957	1.00
414_A	418_V	1.931	1.00
19_S	224_S	1.928	1.00
3_R	235_S	1.916	1.00
132_V	138_A	1.907	1.00
69_R	73_G	1.851	1.00
147_A	151_L	1.850	1.00
190_G	194_A	1.842	1.00
151_L	155_R	1.824	1.00
365_A	369_V	1.822	1.00
116_S	302_G	1.819	1.00
131_T	134_Y	1.817	1.00
54_V	251_A	1.816	1.00
382_L	387_V	1.813	1.00
131_T	135_G	1.812	1.00
10_L	14_M	1.798	1.00
53_G	223_L	1.769	1.00
254_N	258_G	1.745	1.00
180_A	264_V	1.731	1.00
334_V	339_A	1.722	1.00
117_L	303_A	1.715	1.00
110_L	310_S	1.713	1.00
48_V	216_A	1.707	1.00
142_H	351_G	1.704	1.00
139_V	355_A	1.704	1.00
412_L	416_G	1.691	1.00
132_V	136_L	1.689	1.00
79_S	83_L	1.689	1.00
139_V	142_H	1.685	1.00
182_W	186_L	1.685	1.00
106_G	313_A	1.673	1.00
113_F	310_S	1.669	1.00
70_S	330_D	1.642	1.00
197_L	259_V	1.636	1.00
187_D	271_A	1.632	1.00
232_T	323_L	1.626	1.00
334_V	342_L	1.622	1.00
341_A	345_G	1.615	1.00
274_G	277_G	1.606	1.00
5_V	68_R	1.601	1.00
352_S	356_L	1.577	1.00
155_R	163_N	1.562	1.00
115_A	128_Y	1.559	1.00
180_A	260_L	1.556	1.00
19_S	319_S	1.555	1.00
17_V	21_V	1.554	1.00
66_R	395_E	1.553	1.00
350_T	353_A	1.549	1.00
375_A	427_L	1.547	1.00
98_L	368_L	1.545	1.00
84_W	383_F	1.543	1.00
196_Y	263_L	1.543	1.00
307_A	311_L	1.529	1.00
395_E	398_L	1.529	1.00
354_T	360_L	1.525	1.00
233_Y	319_S	1.524	1.00
58_L	247_G	1.517	1.00
139_V	143_L	1.474	1.00
61_F	234_A	1.460	1.00
174_V	178_V	1.449	1.00
83_L	86_V	1.447	1.00
44_V	212_L	1.446	1.00
131_T	138_A	1.433	1.00
73_G	331_E	1.433	1.00
413_Y	417_V	1.429	1.00
356_L	359_G	1.427	1.00
34_S	277_G	1.419	1.00
106_G	145_F	1.400	1.00
378_I	424_I	1.394	1.00
176_L	264_V	1.392	1.00
204_L	211_I	1.389	1.00
11_G	162_E	1.387	1.00
183_A	268_L	1.385	1.00
181_A	185_T	1.385	1.00
226_G	377_L	1.377	1.00
42_L	259_V	1.364	1.00
58_L	243_L	1.359	1.00
130_A	133_S	1.359	1.00
326_S	330_D	1.349	1.00
385_G	416_G	1.340	1.00
391_N	412_L	1.334	1.00
75_F	231_I	1.328	1.00
196_Y	259_V	1.325	1.00
268_L	291_A	1.324	1.00
154_V	337_R	1.324	1.00
224_S	229_T	1.311	1.00
99_L	317_S	1.309	1.00
90_L	376_G	1.287	1.00
70_S	73_G	1.274	1.00
363_F	367_T	1.269	1.00
182_W	296_P	1.268	1.00
40_A	201_V	1.267	1.00
361_F	365_A	1.265	1.00
354_T	364_V	1.260	1.00
98_L	227_S	1.259	1.00
147_A	348_T	1.258	1.00
133_S	138_A	1.249	1.00
71_P	74_A	1.247	1.00
345_G	349_V	1.244	1.00
36_N	211_I	1.242	1.00
7_H	10_L	1.241	1.00
388_V	392_A	1.238	1.00
101_F	365_A	1.234	1.00
252_V	256_C	1.224	1.00
44_V	204_L	1.224	1.00
202_E	205_E	1.224	1.00
92_V	327_F	1.213	1.00
100_S	350_T	1.212	1.00
229_T	320_M	1.210	1.00
3_R	330_D	1.181	1.00
329_V	339_A	1.174	1.00
18_G	315_S	1.170	1.00
51_C	55_P	1.154	1.00
409_T	412_L	1.153	1.00
284_L	287_G	1.151	1.00
282_G	286_V	1.141	1.00
32_M	214_A	1.139	1.00
61_F	250_I	1.139	1.00
134_Y	137_D	1.139	1.00
61_F	230_M	1.131	0.99
410_P	414_A	1.130	0.99
140_G	144_L	1.126	0.99
349_V	353_A	1.126	0.99
184_S	189_A	1.122	0.99
71_P	228_G	1.122	0.99
391_N	416_G	1.120	0.99
99_L	347_F	1.119	0.99
141_F	144_L	1.118	0.99
270_F	277_G	1.116	0.99
338_R	342_L	1.109	0.99
124_N	127_Q	1.109	0.99
421_V	425_F	1.107	0.99
6_W	15_A	1.106	0.99
153_V	325_V	1.106	0.99
378_I	427_L	1.104	0.99
28_R	365_A	1.097	0.99
59_A	411_W	1.096	0.99
100_S	354_T	1.086	0.99
255_T	259_V	1.079	0.99
36_N	214_A	1.079	0.99
154_V	341_A	1.078	0.99
121_Y	124_N	1.077	0.99
61_F	247_G	1.074	0.99
219_A	254_N	1.074	0.99
58_L	62_V	1.063	0.99
303_A	307_A	1.063	0.99
315_S	318_I	1.059	0.99
44_V	211_I	1.056	0.99
179_L	264_V	1.055	0.99
99_L	321_L	1.051	0.99
206_A	211_I	1.050	0.99
219_A	255_T	1.047	0.99
97_V	368_L	1.046	0.99
12_F	16_A	1.044	0.99
413_Y	418_V	1.044	0.99
425_F	429_S	1.043	0.99
94_I	372_L	1.041	0.99
132_V	137_D	1.040	0.99
133_S	137_D	1.040	0.99
178_V	182_W	1.039	0.99
5_V	238_D	1.037	0.99
28_R	32_M	1.037	0.99
62_V	396_Y	1.026	0.99
175_L	304_V	1.023	0.99
150_G	340_T	1.022	0.99
187_D	192_G	1.017	0.99
178_V	301_V	1.016	0.99
7_H	11_G	1.015	0.99
114_G	148_I	1.010	0.99
241_R	246_D	1.008	0.99
131_T	136_L	1.008	0.99
358_P	361_F	1.007	0.99
26_L	312_A	1.006	0.99
244_A	247_G	1.003	0.99
130_A	134_Y	0.998	0.99
177_I	180_A	0.992	0.99
96_V	346_V	0.992	0.99
8_S	11_G	0.985	0.99
51_C	216_A	0.984	0.99
26_L	309_V	0.984	0.99
228_G	323_L	0.984	0.99
106_G	317_S	0.983	0.99
49_V	219_A	0.981	0.99
278_T	282_G	0.977	0.99
146_L	150_G	0.975	0.98
40_A	204_L	0.974	0.98
328_L	334_V	0.971	0.98
255_T	258_G	0.969	0.98
56_G	423_L	0.969	0.98
99_L	320_M	0.966	0.98
13_I	17_V	0.953	0.98
325_V	340_T	0.952	0.98
409_T	413_Y	0.949	0.98
32_M	218_Q	0.948	0.98
164_A	168_M	0.948	0.98
85_R	331_E	0.943	0.98
142_H	146_L	0.938	0.98
355_A	359_G	0.936	0.98
103_S	142_H	0.931	0.98
104_V	355_A	0.929	0.98
114_G	117_L	0.927	0.98
165_T	315_S	0.926	0.98
27_W	31_W	0.925	0.98
4_D	158_K	0.923	0.98
49_V	255_T	0.915	0.98
86_V	89_H	0.914	0.98
371_L	431_I	0.908	0.98
410_P	413_Y	0.904	0.98
229_T	319_S	0.904	0.98
178_V	304_V	0.903	0.98
124_N	293_V	0.902	0.97
204_L	212_L	0.901	0.97
281_P	284_L	0.899	0.97
391_N	394_T	0.895	0.97
186_L	189_A	0.894	0.97
292_F	302_G	0.891	0.97
98_L	320_M	0.891	0.97
178_V	181_A	0.890	0.97
47_G	50_L	0.890	0.97
85_R	89_H	0.890	0.97
71_P	91_S	0.888	0.97
152_I	314_I	0.886	0.97
33_T	196_Y	0.886	0.97
328_L	339_A	0.883	0.97
276_A	279_G	0.878	0.97
189_A	192_G	0.877	0.97
146_L	347_F	0.875	0.97
101_F	369_V	0.874	0.97
385_G	415_V	0.874	0.97
67_S	77_S	0.873	0.97
87_F	379_G	0.872	0.97
335_S	339_A	0.871	0.97
129_F	133_S	0.870	0.97
421_V	424_I	0.870	0.97
70_S	326_S	0.869	0.97
362_D	365_A	0.868	0.97
16_A	19_S	0.868	0.97
32_M	36_N	0.861	0.97
397_E	406_A	0.855	0.97
62_V	393_V	0.854	0.97
182_W	295_V	0.854	0.97
193_L	197_L	0.851	0.96
131_T	137_D	0.850	0.96
295_V	301_V	0.849	0.96
52_V	422_F	0.849	0.96
34_S	195_F	0.847	0.96
180_A	184_S	0.843	0.96
34_S	274_G	0.842	0.96
226_G	373_M	0.837	0.96
366_G	371_L	0.836	0.96
227_S	373_M	0.835	0.96
227_S	320_M	0.829	0.96
47_G	51_C	0.828	0.96
318_I	322_E	0.826	0.96
407_L	410_P	0.825	0.96
357_S	361_F	0.824	0.96
295_V	298_G	0.824	0.96
59_A	384_T	0.822	0.96
105_V	108_W	0.817	0.96
71_P	231_I	0.817	0.96
13_I	250_I	0.816	0.95
78_L	388_V	0.814	0.95
183_A	267_P	0.813	0.95
238_D	241_R	0.809	0.95
148_I	314_I	0.808	0.95
419_I	422_F	0.803	0.95
118_T	121_Y	0.802	0.95
328_L	332_Y	0.801	0.95
17_V	315_S	0.800	0.95
34_S	269_L	0.797	0.95
128_Y	133_S	0.797	0.95
171_A	311_L	0.796	0.95
72_V	327_F	0.794	0.95
25_N	45_Y	0.793	0.95
6_W	12_F	0.792	0.95
95_A	324_P	0.790	0.95
19_S	229_T	0.790	0.95
33_T	262_G	0.790	0.95
206_A	212_L	0.789	0.95
290_N	294_A	0.788	0.95
150_G	341_A	0.786	0.94
339_A	342_L	0.786	0.94
353_A	360_L	0.783	0.94
46_L	255_T	0.782	0.94
265_V	289_A	0.781	0.94
272_L	294_A	0.778	0.94
168_M	311_L	0.775	0.94
73_G	76_S	0.774	0.94
114_G	141_F	0.771	0.94
24_G	28_R	0.770	0.94
225_L	229_T	0.770	0.94
149_T	314_I	0.769	0.94
15_A	233_Y	0.767	0.94
66_R	394_T	0.767	0.94
278_T	287_G	0.766	0.94
388_V	395_E	0.765	0.94
152_I	164_A	0.765	0.94
344_V	348_T	0.764	0.94
79_S	84_W	0.761	0.93
267_P	271_A	0.758	0.93
151_L	154_V	0.756	0.93
15_A	19_S	0.755	0.93
57_L	61_F	0.755	0.93
378_I	382_L	0.753	0.93
207_D	212_L	0.750	0.93
324_P	343_F	0.749	0.93
161_I	318_I	0.748	0.93
249_A	253_L	0.746	0.93
234_A	254_N	0.744	0.93
168_M	315_S	0.743	0.93
394_T	406_A	0.740	0.92
76_S	88_G	0.738	0.92
218_Q	222_T	0.738	0.92
109_I	309_V	0.737	0.92
21_V	25_N	0.737	0.92
103_S	317_S	0.735	0.92
220_L	377_L	0.735	0.92
100_S	317_S	0.735	0.92
375_A	379_G	0.733	0.92
76_S	331_E	0.733	0.92
129_F	136_L	0.733	0.92
113_F	117_L	0.732	0.92
299_R	303_A	0.732	0.92
417_V	421_V	0.732	0.92
381_L	385_G	0.730	0.92
144_L	148_I	0.730	0.92
248_A	252_V	0.730	0.92
16_A	250_I	0.729	0.92
6_W	411_W	0.729	0.92
33_T	42_L	0.729	0.92
427_L	431_I	0.729	0.92
163_N	167_L	0.728	0.92
414_A	419_I	0.726	0.92
334_V	338_R	0.724	0.92
19_S	98_L	0.723	0.92
72_V	88_G	0.721	0.92
34_S	270_F	0.720	0.91
397_E	408_S	0.719	0.91
275_D	287_G	0.717	0.91
406_A	409_T	0.715	0.91
32_M	211_I	0.712	0.91
386_W	416_G	0.711	0.91
103_S	149_T	0.710	0.91
321_L	340_T	0.707	0.91
332_Y	339_A	0.706	0.91
290_N	293_V	0.705	0.91
71_P	327_F	0.705	0.91
32_M	35_E	0.704	0.91
56_G	381_L	0.702	0.90
281_P	286_V	0.702	0.90
155_R	158_K	0.702	0.90
9_R	246_D	0.700	0.90
346_V	350_T	0.699	0.90
329_V	336_R	0.697	0.90
33_T	39_A	0.696	0.90
328_L	346_V	0.696	0.90
110_L	148_I	0.695	0.90
54_V	230_M	0.694	0.90
266_F	271_A	0.693	0.90
79_S	383_F	0.692	0.90
88_G	101_F	0.691	0.90
12_F	61_F	0.690	0.90
9_R	245_A	0.690	0.90
146_L	348_T	0.689	0.90
340_T	344_V	0.689	0.90
390_Q	412_L	0.685	0.89
95_A	229_T	0.682	0.89
95_A	228_G	0.682	0.89
57_L	225_L	0.681	0.89
48_V	51_C	0.680	0.89
173_V	177_I	0.679	0.89
364_V	368_L	0.679	0.89
271_A	294_A	0.678	0.89
131_T	140_G	0.677	0.89
144_L	147_A	0.676	0.89
378_I	381_L	0.675	0.89
236_Y	326_S	0.674	0.89
236_Y	322_E	0.673	0.88
35_E	214_A	0.671	0.88
408_S	411_W	0.670	0.88
56_G	219_A	0.669	0.88
11_G	165_T	0.667	0.88
74_A	231_I	0.666	0.88
172_V	308_V	0.666	0.88
403_V	407_L	0.663	0.88
361_F	364_V	0.662	0.88
46_L	50_L	0.661	0.88
126_G	286_V	0.658	0.87
67_S	78_L	0.658	0.87
63_I	78_L	0.656	0.87
280_G	283_A	0.656	0.87
95_A	323_L	0.655	0.87
320_M	324_P	0.652	0.87
27_W	281_P	0.652	0.87
211_I	214_A	0.651	0.87
92_V	323_L	0.651	0.87
56_G	419_I	0.651	0.87
245_A	249_A	0.651	0.87
224_S	319_S	0.650	0.87
180_A	193_L	0.647	0.86
34_S	276_A	0.647	0.86
321_L	343_F	0.646	0.86
75_F	380_F	0.644	0.86
61_F	243_L	0.643	0.86
110_L	149_T	0.642	0.86
183_A	266_F	0.642	0.86
40_A	44_V	0.640	0.86
383_F	387_V	0.638	0.86
54_V	247_G	0.637	0.86
71_P	92_V	0.636	0.86
93_V	97_V	0.632	0.85
33_T	204_L	0.632	0.85
411_W	415_V	0.630	0.85
65_R	395_E	0.628	0.85
269_L	277_G	0.628	0.85
58_L	244_A	0.628	0.85
58_L	396_Y	0.627	0.85
103_S	146_L	0.627	0.85
25_N	255_T	0.626	0.85
379_G	382_L	0.625	0.85
94_I	376_G	0.621	0.84
22_G	29_F	0.621	0.84
45_Y	222_T	0.618	0.84
86_V	90_L	0.617	0.84
130_A	135_G	0.616	0.84
103_S	145_F	0.616	0.84
146_L	351_G	0.614	0.83
194_A	197_L	0.613	0.83
193_L	199_P	0.613	0.83
28_R	105_V	0.612	0.83
28_R	369_V	0.611	0.83
122_F	125_P	0.609	0.83
25_N	258_G	0.609	0.83
322_E	329_V	0.606	0.83
338_R	341_A	0.606	0.83
155_R	159_R	0.605	0.83
73_G	77_S	0.605	0.83
302_G	306_F	0.604	0.82
106_G	310_S	0.604	0.82
10_L	17_V	0.603	0.82
96_V	347_F	0.603	0.82
412_L	417_V	0.602	0.82
425_F	428_V	0.602	0.82
115_A	120_A	0.602	0.82
31_W	277_G	0.602	0.82
202_E	206_A	0.601	0.82
153_V	317_S	0.600	0.82
187_D	190_G	0.599	0.82
404_A	407_L	0.598	0.82
111_R	114_G	0.598	0.82
148_I	155_R	0.597	0.82
12_F	237_L	0.596	0.82
57_L	251_A	0.594	0.81
114_G	118_T	0.594	0.81
328_L	343_F	0.593	0.81
100_S	364_V	0.593	0.81
188_G	192_G	0.593	0.81
235_S	330_D	0.591	0.81
233_Y	316_S	0.591	0.81
224_S	320_M	0.590	0.81
10_L	13_I	0.590	0.81
59_A	415_V	0.590	0.81
14_M	18_G	0.589	0.81
153_V	340_T	0.585	0.80
96_V	343_F	0.584	0.80
247_G	251_A	0.584	0.80
66_R	388_V	0.583	0.80
90_L	379_G	0.583	0.80
202_E	207_D	0.582	0.80
203_L	211_I	0.582	0.80
362_D	366_G	0.581	0.80
312_A	315_S	0.581	0.80
185_T	188_G	0.580	0.80
391_N	417_V	0.580	0.80
50_L	53_G	0.579	0.80
110_L	347_F	0.577	0.80
101_F	361_F	0.577	0.80
232_T	319_S	0.576	0.79
229_T	381_L	0.576	0.79
25_N	49_V	0.575	0.79
269_L	287_G	0.574	0.79
31_W	281_P	0.574	0.79
97_V	364_V	0.573	0.79
99_L	153_V	0.573	0.79
119_G	122_F	0.572	0.79
58_L	314_I	0.571	0.79
163_N	166_K	0.571	0.79
211_I	218_Q	0.570	0.79
12_F	411_W	0.570	0.79
16_A	57_L	0.569	0.79
182_W	187_D	0.569	0.79
87_F	383_F	0.568	0.78
24_G	27_W	0.568	0.78
98_L	369_V	0.566	0.78
16_A	230_M	0.566	0.78
111_R	141_F	0.565	0.78
267_P	270_F	0.565	0.78
66_R	392_A	0.560	0.78
237_L	241_R	0.559	0.77
171_A	178_V	0.559	0.77
222_T	254_N	0.559	0.77
101_F	227_S	0.558	0.77
394_T	398_L	0.558	0.77
91_S	376_G	0.557	0.77
59_A	62_V	0.557	0.77
119_G	299_R	0.556	0.77
192_G	301_V	0.555	0.77
117_L	120_A	0.554	0.77
13_I	249_A	0.553	0.77
184_S	187_D	0.552	0.77
60_E	64_G	0.551	0.76
66_R	83_L	0.551	0.76
30_P	37_G	0.551	0.76
27_W	30_P	0.550	0.76
110_L	114_G	0.549	0.76
324_P	345_G	0.546	0.76
182_W	192_G	0.546	0.76
330_D	334_V	0.545	0.76
161_I	170_P	0.545	0.76
283_A	289_A	0.545	0.76
397_E	403_V	0.545	0.76
224_S	230_M	0.544	0.75
408_S	412_L	0.542	0.75
339_A	343_F	0.541	0.75
48_V	219_A	0.541	0.75
221_F	233_Y	0.540	0.75
186_L	192_G	0.540	0.75
223_L	255_T	0.540	0.75
239_E	395_E	0.540	0.75
126_G	130_A	0.539	0.75
153_V	318_I	0.538	0.75
234_A	423_L	0.538	0.75
127_Q	130_A	0.538	0.75
120_A	124_N	0.537	0.75
189_A	193_L	0.537	0.75
342_L	346_V	0.537	0.75
226_G	323_L	0.536	0.74
243_L	247_G	0.535	0.74
305_F	322_E	0.535	0.74
39_A	56_G	0.534	0.74
96_V	324_P	0.534	0.74
353_A	364_V	0.534	0.74
188_G	191_A	0.534	0.74
244_A	248_A	0.533	0.74
228_G	318_I	0.533	0.74
176_L	261_A	0.531	0.74
63_I	384_T	0.531	0.74
317_S	351_G	0.527	0.73
382_L	386_W	0.526	0.73
108_W	112_Y	0.525	0.73
49_V	251_A	0.524	0.73
285_F	305_F	0.523	0.73
105_V	354_T	0.520	0.72
37_G	41_F	0.520	0.72
17_V	316_S	0.519	0.72
221_F	225_L	0.518	0.72
156_G	318_I	0.517	0.72
68_R	419_I	0.517	0.72
125_P	128_Y	0.516	0.72
84_W	87_F	0.516	0.72
39_A	199_P	0.516	0.72
25_N	222_T	0.516	0.72
325_V	329_V	0.515	0.71
53_G	219_A	0.515	0.71
183_A	264_V	0.515	0.71
393_V	408_S	0.513	0.71
188_G	271_A	0.513	0.71
86_V	165_T	0.513	0.71
195_F	270_F	0.512	0.71
120_A	299_R	0.512	0.71
405_S	408_S	0.512	0.71
66_R	78_L	0.512	0.71
105_V	281_P	0.511	0.71
180_A	267_P	0.510	0.71
376_G	380_F	0.509	0.71
386_W	417_V	0.509	0.71
228_G	330_D	0.509	0.71
329_V	332_Y	0.509	0.71
92_V	324_P	0.508	0.70
341_A	344_V	0.506	0.70
316_S	319_S	0.505	0.70
27_W	37_G	0.505	0.70
71_P	229_T	0.503	0.70
403_V	406_A	0.503	0.70
272_L	291_A	0.502	0.70
116_S	121_Y	0.501	0.69
178_V	184_S	0.501	0.69
6_W	53_G	0.500	0.69

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
4xp4A	1	0.9811	100	0.038	Contact Map
2a65A	2	0.9769	100	0.075	Contact Map
4us3A	1	0.8889	100	0.082	Contact Map
3giaA	1	0.8491	98.2	0.919	Contact Map
4djkA	2	0.8616	97.7	0.926	Contact Map
3l1lA	2	0.8281	97.4	0.931	Contact Map
2jlnA	1	0.8491	95.3	0.945	Contact Map
2xq2A	2	0.8931	88.6	0.956	Contact Map
4wgvA	2	0.761	87.4	0.956	Contact Map
3dh4A	3	0.8658	86.5	0.957	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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