Q9HPQ0 - HALSA - GREMLIN Contacts

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Q9HPQ0 - Methylmalonyl-CoA decarboxylase, subunit alpha

UniProt:	Q9HPQ0	Sequences: MTMEERIEDLREQTERALLGGGEARIESQHEKGKLTARERIDYFLDDGTFNELDQLRTHRSTNFDMDETKLPGDGVVTGYGDVNGRTTFVFAHDFTVFGGSLGEVFAEKVTKVMDRAMEVGAPVVGLNDSAGARIQEGVDALGGFAEIFTRNEKASGVVPQISAIMGPCAGGAVYSPAITDFTVMVKDTSHMFITGPDVIETVTGEQVGFEELGGATTHAAESGVAHFACDSEEAALDNIKRLLSYLPQNNVEDPPRVEPYDDPERRDDALETIVPDEPRKPYDMTDVVDSVVDEQSFFEVQADYAKNIVVGFARLDGRSVGIVANQPRVNAGTLDIDASEKGSRFVRFCDSFNVPILTLVDVPGFLPGTDQEHGGIIRHGAKLLYAFSEASVPLMTVITRKAYGGAYDVMASKHIGADVNYAWPTAEIAVMGPKGAVNVLYSDELEAADDTAARRQELIDEYREEFANPYTAADRGYLDAVIEPTETRPRLIDDLDMLASKREETPDKKHGNIPL	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	516 (488)
Sequences:	5069 (2253)
Seq/√Len:	102.0

BACSU - PCCB YNGE
HALSA - Q9HPQ0 Q9HRN1
SULSO - Q97VY8

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
298_F	312_G	4.863	1.00
293_V	314_A	4.768	1.00
285_M	310_V	4.683	1.00
309_I	343_G	4.256	1.00
209_G	212_E	4.229	1.00
187_K	231_D	4.146	1.00
45_L	81_G	4.105	1.00
23_E	27_E	3.916	1.00
45_L	90_V	3.796	1.00
164_A	240_I	3.625	1.00
201_E	207_Q	3.376	1.00
292_V	360_L	3.363	1.00
49_T	82_D	3.195	1.00
115_D	151_R	3.000	1.00
316_L	492_L	2.953	1.00
322_G	350_C	2.919	1.00
272_E	486_T	2.899	1.00
358_L	496_L	2.876	1.00
361_V	397_T	2.745	1.00
457_Q	461_D	2.739	1.00
398_V	488_T	2.684	1.00
285_M	400_T	2.670	1.00
27_E	31_E	2.610	1.00
262_D	266_R	2.530	1.00
184_V	240_I	2.498	1.00
50_F	79_G	2.469	1.00
272_E	484_E	2.391	1.00
228_F	301_V	2.373	1.00
314_A	323_I	2.295	1.00
232_S	235_A	2.285	1.00
341_E	380_H	2.248	1.00
220_A	304_D	2.230	1.00
89_F	113_V	2.226	1.00
461_D	465_E	2.215	1.00
424_W	488_T	2.171	1.00
163_S	180_T	2.166	1.00
293_V	323_I	2.137	1.00
317_D	493_I	2.118	1.00
37_A	77_V	2.111	1.00
220_A	226_A	2.109	1.00
216_A	229_A	2.098	1.00
230_C	239_N	2.062	1.00
30_H	39_E	2.052	1.00
9_D	13_Q	2.051	1.00
451_D	454_A	2.050	1.00
462_E	466_E	2.031	1.00
268_D	291_S	2.031	1.00
184_V	236_A	2.029	1.00
26_I	30_H	2.020	1.00
455_R	458_E	2.017	1.00
89_F	122_A	2.014	1.00
396_M	496_L	2.012	1.00
208_V	370_T	1.999	1.00
487_E	490_P	1.981	1.00
321_V	358_L	1.974	1.00
358_L	492_L	1.949	1.00
187_K	217_T	1.936	1.00
262_D	297_S	1.934	1.00
35_L	43_Y	1.929	1.00
360_L	398_V	1.927	1.00
288_V	400_T	1.923	1.00
118_M	155_A	1.916	1.00
231_D	235_A	1.894	1.00
316_L	493_I	1.861	1.00
289_V	293_V	1.855	1.00
317_D	497_D	1.842	1.00
54_D	112_K	1.825	1.00
319_R	500_A	1.800	1.00
185_M	190_S	1.794	1.00
246_Y	297_S	1.792	1.00
220_A	229_A	1.764	1.00
265_E	295_E	1.760	1.00
8_E	12_E	1.749	1.00
351_D	392_S	1.736	1.00
43_Y	234_E	1.728	1.00
41_I	45_L	1.727	1.00
217_T	221_A	1.721	1.00
84_N	245_S	1.716	1.00
218_T	374_H	1.713	1.00
235_A	239_N	1.696	1.00
423_A	427_A	1.682	1.00
58_T	74_D	1.679	1.00
452_T	456_R	1.673	1.00
86_R	248_P	1.666	1.00
41_I	90_V	1.665	1.00
37_A	92_A	1.663	1.00
87_T	122_A	1.662	1.00
76_V	110_V	1.662	1.00
343_G	384_L	1.653	1.00
14_T	481_A	1.632	1.00
184_V	243_L	1.630	1.00
166_M	233_E	1.629	1.00
184_V	239_N	1.610	1.00
227_H	302_Q	1.580	1.00
11_R	484_E	1.562	1.00
91_F	126_G	1.561	1.00
127_L	164_A	1.560	1.00
222_E	374_H	1.554	1.00
14_T	55_Q	1.552	1.00
44_F	83_V	1.540	1.00
45_L	49_T	1.534	1.00
19_L	23_E	1.529	1.00
43_Y	238_D	1.527	1.00
114_M	124_V	1.521	1.00
184_V	230_C	1.498	1.00
134_R	137_E	1.494	1.00
396_M	492_L	1.488	1.00
481_A	491_R	1.487	1.00
187_K	229_A	1.470	1.00
370_T	374_H	1.468	1.00
60_R	104_E	1.465	1.00
43_Y	237_L	1.465	1.00
420_V	495_D	1.462	1.00
347_V	391_A	1.444	1.00
422_Y	491_R	1.441	1.00
9_D	12_E	1.439	1.00
289_V	360_L	1.427	1.00
449_A	455_R	1.418	1.00
57_R	105_V	1.417	1.00
286_T	300_E	1.414	1.00
434_P	464_R	1.401	1.00
270_A	291_S	1.398	1.00
74_D	105_V	1.392	1.00
358_L	396_M	1.384	1.00
305_Y	338_D	1.357	0.99
289_V	323_I	1.354	0.99
118_M	157_G	1.354	0.99
28_S	31_E	1.346	0.99
446_L	449_A	1.346	0.99
140_D	476_R	1.340	0.99
351_D	391_A	1.338	0.99
323_I	358_L	1.314	0.99
166_M	237_L	1.308	0.99
101_S	131_A	1.298	0.99
461_D	464_R	1.294	0.99
242_R	297_S	1.293	0.99
10_L	471_Y	1.282	0.99
451_D	455_R	1.277	0.99
398_V	492_L	1.277	0.99
82_D	87_T	1.269	0.99
18_L	55_Q	1.268	0.99
13_Q	16_R	1.268	0.99
337_I	375_G	1.268	0.99
86_R	249_Q	1.267	0.99
55_Q	481_A	1.266	0.99
348_R	390_E	1.264	0.99
78_T	113_V	1.263	0.99
320_S	355_V	1.263	0.99
114_M	151_R	1.258	0.99
15_E	18_L	1.251	0.99
418_A	421_N	1.248	0.99
118_M	154_K	1.248	0.99
26_I	36_T	1.243	0.99
230_C	235_A	1.243	0.99
269_D	272_E	1.242	0.99
193_F	210_F	1.241	0.99
19_L	26_I	1.236	0.99
127_L	166_M	1.226	0.99
22_G	26_I	1.225	0.99
236_A	240_I	1.225	0.99
435_K	460_I	1.223	0.99
284_D	287_D	1.219	0.99
17_A	56_L	1.217	0.99
484_E	487_E	1.217	0.99
396_M	495_D	1.200	0.99
11_R	14_T	1.200	0.99
9_D	469_N	1.195	0.99
403_A	408_Y	1.195	0.99
286_T	310_V	1.193	0.99
24_A	27_E	1.189	0.99
396_M	499_L	1.188	0.99
127_L	237_L	1.181	0.98
152_N	176_S	1.177	0.98
221_A	304_D	1.170	0.98
212_E	370_T	1.168	0.98
293_V	316_L	1.164	0.98
23_E	26_I	1.160	0.98
228_F	239_N	1.153	0.98
13_Q	471_Y	1.149	0.98
302_Q	311_V	1.147	0.98
58_T	105_V	1.141	0.98
182_F	228_F	1.134	0.98
14_T	18_L	1.131	0.98
41_I	92_A	1.127	0.98
82_D	497_D	1.126	0.98
404_Y	428_E	1.126	0.98
36_T	39_E	1.121	0.98
437_A	463_Y	1.121	0.98
270_A	273_T	1.119	0.98
12_E	16_R	1.114	0.98
485_P	488_T	1.110	0.98
289_V	312_G	1.110	0.98
422_Y	495_D	1.108	0.98
239_N	242_R	1.107	0.98
453_A	456_R	1.106	0.98
347_V	357_I	1.103	0.98
228_F	303_A	1.100	0.98
110_V	148_I	1.097	0.98
155_A	159_V	1.097	0.98
119_E	419_D	1.090	0.97
359_T	388_F	1.088	0.97
230_C	236_A	1.084	0.97
74_D	134_R	1.083	0.97
17_A	73_G	1.080	0.97
235_A	238_D	1.073	0.97
152_N	161_Q	1.068	0.97
289_V	298_F	1.062	0.97
14_T	487_E	1.055	0.97
263_D	266_R	1.053	0.97
366_F	410_V	1.053	0.97
284_D	327_Q	1.052	0.97
269_D	486_T	1.052	0.97
146_A	409_D	1.049	0.97
433_G	436_G	1.049	0.97
21_G	96_T	1.048	0.97
217_T	304_D	1.043	0.97
12_E	15_E	1.039	0.97
300_E	303_A	1.037	0.97
435_K	464_R	1.034	0.96
19_L	22_G	1.033	0.96
429_I	473_A	1.030	0.96
428_E	464_R	1.029	0.96
89_F	120_V	1.028	0.96
80_Y	89_F	1.027	0.96
326_N	411_M	1.027	0.96
30_H	36_T	1.026	0.96
449_A	452_T	1.024	0.96
107_A	144_G	1.019	0.96
438_V	459_L	1.018	0.96
446_L	452_T	1.016	0.96
147_E	415_H	1.013	0.96
198_D	443_S	1.012	0.96
143_G	415_H	1.011	0.96
150_T	154_K	1.008	0.96
459_L	462_E	1.007	0.96
422_Y	481_A	0.999	0.96
228_F	299_F	0.998	0.96
51_N	494_D	0.996	0.96
321_V	496_L	0.993	0.96
229_A	304_D	0.991	0.95
35_L	233_E	0.990	0.95
54_D	78_T	0.988	0.95
166_M	189_T	0.986	0.95
116_R	120_V	0.984	0.95
445_E	449_A	0.981	0.95
162_I	240_I	0.978	0.95
164_A	184_V	0.978	0.95
233_E	237_L	0.977	0.95
95_F	168_P	0.974	0.95
239_N	299_F	0.973	0.95
252_V	503_R	0.972	0.95
358_L	398_V	0.969	0.95
53_L	116_R	0.964	0.95
58_T	70_K	0.962	0.95
111_T	151_R	0.960	0.95
206_E	370_T	0.959	0.95
108_E	147_E	0.959	0.95
29_Q	34_K	0.958	0.95
71_L	98_F	0.956	0.94
242_R	299_F	0.955	0.94
29_Q	95_F	0.955	0.94
38_R	52_E	0.952	0.94
84_N	249_Q	0.947	0.94
166_M	186_V	0.946	0.94
80_Y	87_T	0.945	0.94
287_D	290_D	0.941	0.94
87_T	497_D	0.938	0.94
39_E	42_D	0.937	0.94
307_K	330_V	0.935	0.94
343_G	347_V	0.935	0.94
388_F	412_A	0.933	0.94
28_S	32_K	0.931	0.94
208_V	212_E	0.931	0.94
53_L	78_T	0.930	0.94
87_T	498_M	0.929	0.94
344_S	387_A	0.927	0.94
402_K	428_E	0.927	0.94
237_L	241_K	0.926	0.94
445_E	448_A	0.923	0.93
319_R	497_D	0.921	0.93
120_V	419_D	0.917	0.93
18_L	42_D	0.917	0.93
121_G	157_G	0.914	0.93
316_L	398_V	0.913	0.93
182_F	243_L	0.910	0.93
293_V	358_L	0.908	0.93
455_R	459_L	0.905	0.93
81_G	90_V	0.902	0.93
414_K	480_D	0.902	0.93
286_T	327_Q	0.898	0.92
80_Y	122_A	0.898	0.92
423_A	473_A	0.898	0.92
51_N	80_Y	0.897	0.92
395_L	412_A	0.897	0.92
446_L	455_R	0.896	0.92
22_G	25_R	0.895	0.92
130_S	173_A	0.894	0.92
309_I	335_L	0.884	0.92
301_V	311_V	0.880	0.92
337_I	380_H	0.876	0.91
371_D	375_G	0.876	0.91
138_G	142_L	0.876	0.91
324_V	347_V	0.871	0.91
103_G	134_R	0.870	0.91
314_A	321_V	0.868	0.91
175_Y	381_G	0.866	0.91
375_G	380_H	0.865	0.91
460_I	464_R	0.865	0.91
452_T	455_R	0.864	0.91
104_E	140_D	0.864	0.91
14_T	56_L	0.864	0.91
409_D	415_H	0.863	0.91
287_D	291_S	0.860	0.91
16_R	70_K	0.857	0.91
439_N	456_R	0.856	0.91
438_V	446_L	0.851	0.90
262_D	265_E	0.850	0.90
422_Y	483_I	0.849	0.90
260_P	266_R	0.849	0.90
146_A	415_H	0.849	0.90
262_D	295_E	0.848	0.90
217_T	229_A	0.845	0.90
58_T	475_D	0.845	0.90
8_E	11_R	0.843	0.90
349_F	353_F	0.843	0.90
458_E	462_E	0.841	0.90
357_I	395_L	0.841	0.90
153_E	179_I	0.840	0.90
93_H	106_F	0.840	0.90
236_A	239_N	0.836	0.89
446_L	459_L	0.835	0.89
399_I	427_A	0.830	0.89
487_E	491_R	0.830	0.89
274_I	291_S	0.830	0.89
174_V	378_I	0.829	0.89
357_I	412_A	0.825	0.89
184_V	228_F	0.823	0.89
483_I	488_T	0.819	0.89
371_D	374_H	0.817	0.88
61_S	67_D	0.817	0.88
298_F	310_V	0.816	0.88
248_P	251_N	0.815	0.88
125_V	244_L	0.815	0.88
456_R	460_I	0.814	0.88
457_Q	460_I	0.814	0.88
360_L	400_T	0.813	0.88
83_V	88_T	0.812	0.88
314_A	358_L	0.807	0.88
156_S	352_S	0.807	0.88
278_E	281_K	0.805	0.88
15_E	19_L	0.804	0.88
102_L	110_V	0.804	0.88
249_Q	253_E	0.803	0.88
84_N	241_K	0.802	0.87
72_P	97_V	0.801	0.87
61_S	105_V	0.800	0.87
399_I	421_N	0.798	0.87
125_V	162_I	0.797	0.87
147_E	417_G	0.797	0.87
424_W	485_P	0.797	0.87
88_T	125_V	0.796	0.87
41_I	77_V	0.793	0.87
420_V	498_M	0.788	0.87
45_L	88_T	0.787	0.86
311_V	346_F	0.785	0.86
118_M	159_V	0.781	0.86
153_E	389_S	0.780	0.86
58_T	61_S	0.779	0.86
83_V	244_L	0.778	0.86
443_S	447_E	0.777	0.86
164_A	237_L	0.777	0.86
466_E	472_T	0.776	0.86
182_F	349_F	0.773	0.85
80_Y	120_V	0.770	0.85
99_G	131_A	0.768	0.85
150_T	389_S	0.766	0.85
219_H	223_S	0.764	0.85
246_Y	320_S	0.763	0.85
397_T	421_N	0.762	0.85
111_T	115_D	0.762	0.85
106_F	110_V	0.760	0.84
103_G	106_F	0.759	0.84
308_N	336_D	0.757	0.84
53_L	113_V	0.757	0.84
75_G	106_F	0.755	0.84
208_V	374_H	0.755	0.84
316_L	321_V	0.753	0.84
158_V	251_N	0.751	0.84
359_T	395_L	0.748	0.84
87_T	501_S	0.746	0.83
389_S	416_I	0.745	0.83
313_F	349_F	0.745	0.83
234_E	238_D	0.745	0.83
26_I	29_Q	0.743	0.83
29_Q	32_K	0.743	0.83
42_D	47_D	0.742	0.83
399_I	423_A	0.741	0.83
257_R	317_D	0.740	0.83
184_V	299_F	0.739	0.83
52_E	109_K	0.739	0.83
434_P	468_A	0.738	0.83
290_D	297_S	0.738	0.83
244_L	320_S	0.737	0.83
17_A	474_A	0.735	0.82
451_D	456_R	0.734	0.82
341_E	379_R	0.734	0.82
317_D	490_P	0.733	0.82
266_R	290_D	0.732	0.82
250_N	354_N	0.731	0.82
454_A	458_E	0.730	0.82
192_M	378_I	0.730	0.82
149_F	172_G	0.729	0.82
414_K	421_N	0.729	0.82
29_Q	36_T	0.728	0.82
35_L	234_E	0.727	0.82
491_R	494_D	0.727	0.82
497_D	500_A	0.726	0.82
44_F	125_V	0.726	0.82
147_E	151_R	0.726	0.82
87_T	120_V	0.726	0.82
449_A	454_A	0.726	0.82
105_V	108_E	0.725	0.82
104_E	476_R	0.724	0.82
435_K	439_N	0.724	0.82
139_V	466_E	0.719	0.81
116_R	119_E	0.718	0.81
305_Y	341_E	0.716	0.81
257_R	319_R	0.715	0.81
381_G	431_V	0.713	0.81
240_I	243_L	0.713	0.81
300_E	342_K	0.713	0.81
114_M	155_A	0.712	0.80
290_D	296_Q	0.711	0.80
274_I	288_V	0.711	0.80
268_D	271_L	0.711	0.80
44_F	90_V	0.710	0.80
309_I	324_V	0.707	0.80
46_D	49_T	0.706	0.80
121_G	250_N	0.706	0.80
19_L	27_E	0.706	0.80
30_H	37_A	0.705	0.80
164_A	236_A	0.704	0.80
143_G	147_E	0.703	0.80
49_T	79_G	0.700	0.79
474_A	479_L	0.700	0.79
399_I	429_I	0.699	0.79
24_A	28_S	0.697	0.79
396_M	422_Y	0.697	0.79
245_S	315_R	0.697	0.79
335_L	340_S	0.694	0.79
57_R	477_G	0.694	0.79
410_V	421_N	0.693	0.79
89_F	116_R	0.691	0.78
373_E	376_G	0.689	0.78
271_L	288_V	0.689	0.78
490_P	494_D	0.688	0.78
239_N	243_L	0.688	0.78
381_G	433_G	0.687	0.78
472_T	475_D	0.684	0.78
218_T	222_E	0.684	0.78
347_V	388_F	0.684	0.78
10_L	14_T	0.684	0.78
90_V	125_V	0.684	0.78
179_I	386_Y	0.683	0.78
357_I	388_F	0.680	0.77
124_V	159_V	0.678	0.77
425_P	485_P	0.676	0.77
9_D	471_Y	0.675	0.77
361_V	412_A	0.675	0.77
150_T	417_G	0.674	0.77
89_F	498_M	0.674	0.77
115_D	119_E	0.672	0.76
324_V	351_D	0.672	0.76
16_R	19_L	0.671	0.76
11_R	15_E	0.669	0.76
27_E	30_H	0.663	0.76
37_A	41_I	0.662	0.75
83_V	237_L	0.661	0.75
223_S	376_G	0.661	0.75
162_I	243_L	0.661	0.75
185_M	226_A	0.660	0.75
172_G	196_G	0.660	0.75
491_R	495_D	0.656	0.75
472_T	476_R	0.656	0.75
421_N	479_L	0.654	0.75
91_F	124_V	0.654	0.75
348_R	387_A	0.654	0.75
254_D	503_R	0.653	0.74
86_R	256_P	0.650	0.74
133_A	431_V	0.650	0.74
363_V	377_I	0.649	0.74
442_Y	459_L	0.648	0.74
115_D	417_G	0.647	0.74
242_R	245_S	0.647	0.74
56_L	474_A	0.646	0.74
267_R	487_E	0.644	0.73
415_H	478_Y	0.644	0.73
244_L	247_L	0.643	0.73
88_T	248_P	0.643	0.73
257_R	320_S	0.642	0.73
424_W	483_I	0.642	0.73
29_Q	96_T	0.641	0.73
308_N	339_A	0.640	0.73
80_Y	498_M	0.640	0.73
453_A	457_Q	0.639	0.73
358_L	499_L	0.639	0.73
111_T	114_M	0.638	0.73
275_V	279_P	0.638	0.73
450_D	455_R	0.637	0.73
266_R	291_S	0.637	0.73
254_D	319_R	0.635	0.72
34_K	189_T	0.634	0.72
270_A	288_V	0.634	0.72
175_Y	431_V	0.634	0.72
430_A	468_A	0.634	0.72
440_V	443_S	0.634	0.72
266_R	296_Q	0.632	0.72
442_Y	456_R	0.631	0.72
274_I	287_D	0.629	0.72
316_L	396_M	0.629	0.72
202_T	439_N	0.629	0.72
21_G	25_R	0.628	0.72
53_L	89_F	0.627	0.71
470_P	473_A	0.626	0.71
450_D	454_A	0.626	0.71
267_R	292_V	0.625	0.71
13_Q	469_N	0.624	0.71
261_Y	264_P	0.622	0.71
498_M	501_S	0.620	0.71
345_R	379_R	0.619	0.70
14_T	17_A	0.618	0.70
131_A	196_G	0.618	0.70
344_S	347_V	0.617	0.70
99_G	440_V	0.617	0.70
131_A	440_V	0.616	0.70
315_R	320_S	0.616	0.70
279_P	428_E	0.615	0.70
186_V	232_S	0.615	0.70
267_R	270_A	0.614	0.70
268_D	490_P	0.614	0.70
45_L	83_V	0.614	0.70
444_D	448_A	0.610	0.69
8_E	13_Q	0.609	0.69
495_D	499_L	0.609	0.69
263_D	490_P	0.607	0.69
15_E	31_E	0.607	0.69
21_G	26_I	0.606	0.69
246_Y	299_F	0.603	0.68
458_E	461_D	0.603	0.68
492_L	495_D	0.602	0.68
267_R	490_P	0.601	0.68
45_L	82_D	0.601	0.68
156_S	383_K	0.600	0.68
432_M	437_A	0.599	0.68
114_M	126_G	0.599	0.68
341_E	383_K	0.599	0.68
499_L	502_K	0.599	0.68
102_L	145_F	0.599	0.68
423_A	479_L	0.598	0.68
238_D	241_K	0.596	0.68
13_Q	17_A	0.595	0.67
189_T	237_L	0.595	0.67
217_T	231_D	0.595	0.67
304_D	307_K	0.593	0.67
262_D	268_D	0.593	0.67
364_P	402_K	0.592	0.67
111_T	147_E	0.590	0.67
76_V	106_F	0.589	0.67
500_A	503_R	0.589	0.67
450_D	453_A	0.588	0.67
412_A	418_A	0.588	0.67
200_I	439_N	0.587	0.66
75_G	94_D	0.587	0.66
139_V	142_L	0.586	0.66
357_I	391_A	0.586	0.66
34_K	95_F	0.584	0.66
377_I	381_G	0.583	0.66
428_E	468_A	0.583	0.66
460_I	463_Y	0.583	0.66
59_H	67_D	0.583	0.66
154_K	392_S	0.581	0.66
442_Y	445_E	0.581	0.66
496_L	499_L	0.580	0.65
498_M	502_K	0.580	0.65
20_G	97_V	0.577	0.65
255_P	320_S	0.573	0.65
17_A	55_Q	0.572	0.64
380_H	383_K	0.571	0.64
469_N	472_T	0.571	0.64
41_I	49_T	0.571	0.64
179_I	416_I	0.570	0.64
189_T	233_E	0.568	0.64
275_V	288_V	0.568	0.64
129_D	169_C	0.567	0.64
264_P	317_D	0.567	0.64
84_N	88_T	0.566	0.64
271_L	275_V	0.565	0.63
349_F	355_V	0.564	0.63
270_A	274_I	0.563	0.63
163_S	177_P	0.563	0.63
42_D	48_G	0.562	0.63
12_E	23_E	0.562	0.63
77_V	92_A	0.561	0.63
60_R	476_R	0.561	0.63
488_T	492_L	0.560	0.63
497_D	501_S	0.560	0.63
102_L	148_I	0.560	0.63
129_D	173_A	0.558	0.63
193_F	198_D	0.558	0.63
78_T	89_F	0.557	0.62
255_P	319_R	0.555	0.62
121_G	502_K	0.555	0.62
419_D	502_K	0.554	0.62
368_P	406_G	0.553	0.62
56_L	471_Y	0.553	0.62
169_C	463_Y	0.553	0.62
186_V	236_A	0.553	0.62
93_H	114_M	0.552	0.62
278_E	282_P	0.551	0.62
347_V	387_A	0.551	0.62
128_N	173_A	0.551	0.62
16_R	68_E	0.550	0.61
16_R	28_S	0.550	0.61
99_G	127_L	0.550	0.61
469_N	473_A	0.549	0.61
335_L	339_A	0.549	0.61
260_P	317_D	0.549	0.61
175_Y	196_G	0.549	0.61
384_L	411_M	0.549	0.61
83_V	90_V	0.548	0.61
24_A	31_E	0.548	0.61
265_E	297_S	0.548	0.61
322_G	346_F	0.548	0.61
165_I	177_P	0.548	0.61
283_Y	401_R	0.548	0.61
49_T	88_T	0.548	0.61
417_G	473_A	0.547	0.61
285_M	325_A	0.547	0.61
397_T	412_A	0.544	0.61
10_L	13_Q	0.543	0.60
261_Y	266_R	0.543	0.60
293_V	298_F	0.542	0.60
146_A	413_S	0.541	0.60
323_I	492_L	0.540	0.60
344_S	384_L	0.539	0.60
490_P	493_I	0.539	0.60
18_L	22_G	0.539	0.60
216_A	226_A	0.538	0.60
114_M	161_Q	0.538	0.60
259_E	315_R	0.537	0.60
136_Q	172_G	0.537	0.60
172_G	175_Y	0.535	0.59
11_R	17_A	0.534	0.59
334_T	339_A	0.534	0.59
363_V	407_A	0.534	0.59
74_D	98_F	0.533	0.59
170_A	193_F	0.533	0.59
119_E	417_G	0.533	0.59
9_D	450_D	0.532	0.59
341_E	410_V	0.532	0.59
122_A	498_M	0.532	0.59
47_D	261_Y	0.531	0.59
188_D	211_E	0.531	0.59
404_Y	430_A	0.531	0.59
260_P	263_D	0.531	0.59
185_M	223_S	0.530	0.59
352_S	383_K	0.530	0.59
140_D	478_Y	0.530	0.59
267_R	486_T	0.529	0.58
23_E	31_E	0.529	0.58
114_M	152_N	0.527	0.58
147_E	478_Y	0.527	0.58
463_Y	468_A	0.527	0.58
86_R	121_G	0.526	0.58
186_V	233_E	0.526	0.58
227_H	301_V	0.525	0.58
214_G	219_H	0.525	0.58
363_V	366_F	0.523	0.58
22_G	325_A	0.523	0.58
359_T	412_A	0.523	0.58
294_D	318_G	0.522	0.57
301_V	313_F	0.521	0.57
217_T	220_A	0.521	0.57
426_T	470_P	0.521	0.57
8_E	23_E	0.520	0.57
305_Y	380_H	0.520	0.57
286_T	303_A	0.520	0.57
276_P	279_P	0.520	0.57
264_P	268_D	0.520	0.57
45_L	125_V	0.519	0.57
95_F	99_G	0.519	0.57
179_I	194_I	0.518	0.57
298_F	360_L	0.518	0.57
243_L	299_F	0.517	0.57
442_Y	462_E	0.517	0.57
238_D	242_R	0.517	0.57
101_S	134_R	0.516	0.57
13_Q	19_L	0.516	0.57
103_G	379_R	0.515	0.56
495_D	498_M	0.515	0.56
127_L	472_T	0.515	0.56
290_D	303_A	0.514	0.56
172_G	432_M	0.513	0.56
171_G	199_V	0.513	0.56
139_V	472_T	0.512	0.56
369_G	381_G	0.512	0.56
44_F	127_L	0.512	0.56
344_S	348_R	0.511	0.56
265_E	268_D	0.511	0.56
37_A	54_D	0.510	0.56
412_A	417_G	0.510	0.56
289_V	310_V	0.509	0.56
336_D	339_A	0.508	0.55
406_G	409_D	0.508	0.55
121_G	158_V	0.506	0.55
237_L	240_I	0.506	0.55
26_I	96_T	0.505	0.55
182_F	301_V	0.505	0.55
313_F	353_F	0.505	0.55
187_K	497_D	0.505	0.55
179_I	382_A	0.504	0.55
71_L	103_G	0.504	0.55
47_D	269_D	0.504	0.55
149_F	177_P	0.503	0.55
50_F	90_V	0.503	0.55
251_N	254_D	0.503	0.55
129_D	166_M	0.502	0.55
254_D	500_A	0.502	0.55
369_G	376_G	0.501	0.54
149_F	175_Y	0.500	0.54
44_F	237_L	0.500	0.54
266_R	316_L	0.500	0.54

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
1vrgA	4	0.9961	100	0.111	Contact Map
3n6rB	4	0.9806	100	0.12	Contact Map
2bzrA	4	0.9748	100	0.149	Contact Map
3u9rB	5	0.9729	100	0.156	Contact Map
3iavA	4	1	100	0.162	Contact Map
4rcnA	6	0.9205	100	0.169	Contact Map
1on3A	6	0.9961	100	0.174	Contact Map
1x0uA	5	1	100	0.182	Contact Map
1pixA	4	0.9767	100	0.188	Contact Map
3gf3A	4	0.9671	100	0.191	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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