GREMLIN Database
Q9HPN8 - Chloride channel
UniProt: Q9HPN8 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 792 (628)
Sequences: 885 (518)
Seq/√Len: 20.7

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
194_G317_A6.4491.00
602_S606_Q5.7401.00
729_A752_I4.6971.00
684_L721_L4.2241.00
251_I296_I4.1921.00
304_L517_S4.1481.00
422_V537_A4.1311.00
222_A225_H4.0791.00
412_E558_Y3.9361.00
194_G287_A3.8901.00
650_V662_V3.7161.00
250_L454_A3.7091.00
651_T654_T3.6471.00
764_T767_D3.4981.00
190_V317_A3.4821.00
417_A421_V3.4101.00
494_I497_D3.0040.99
198_F291_T2.8030.99
509_L513_G2.7990.99
493_S497_D2.7680.99
486_G495_A2.7240.99
185_I374_L2.7000.99
492_S495_A2.6940.99
196_V386_V2.6430.98
246_A457_G2.6330.98
417_A600_I2.5920.98
642_V735_L2.5720.98
268_V574_P2.4860.98
415_L545_V2.4670.97
221_F225_H2.4450.97
314_G337_G2.4400.97
486_G490_I2.4350.97
491_H497_D2.3100.96
269_P576_T2.2980.96
419_L541_F2.2910.96
751_P759_L2.2460.95
639_A738_L2.2320.95
141_R145_P2.2040.95
182_T656_A2.1780.95
342_I527_F2.1670.94
483_F613_T2.1230.94
418_G657_M2.1020.93
294_S300_S2.0690.93
189_I382_V2.0610.93
648_D662_V2.0490.93
490_I493_S2.0290.92
139_W142_T2.0190.92
139_W147_V1.9780.91
673_I684_L1.9770.91
359_I400_V1.9760.91
342_I359_I1.9740.91
511_V533_V1.9670.91
149_A153_A1.9610.91
150_A157_T1.9600.91
246_A348_T1.9590.91
659_A667_S1.9560.91
236_L508_V1.9300.90
654_T658_D1.9100.90
526_V540_A1.9100.90
441_F452_T1.8670.88
329_Y332_T1.8640.88
303_S510_K1.8620.88
275_L572_S1.8490.88
553_A650_V1.8470.88
304_L518_I1.8420.88
542_G555_A1.8410.88
270_E622_K1.8330.87
656_A660_L1.8170.87
657_M661_R1.8070.87
544_L548_A1.7950.86
426_I566_V1.7940.86
451_L463_S1.7880.86
304_L528_S1.7700.86
268_V272_L1.7690.86
246_A454_A1.7380.84
359_I577_A1.7370.84
265_G342_I1.7360.84
561_V597_V1.7280.84
303_S460_L1.7170.84
272_L616_T1.7040.83
476_L479_A1.6940.83
265_G752_I1.6810.82
386_V693_V1.6740.82
423_A569_A1.6650.82
249_G457_G1.6610.82
492_S496_G1.6470.81
487_Y491_H1.6420.81
650_V653_G1.6390.81
139_W145_P1.6260.80
303_S527_F1.6250.80
308_G346_F1.6200.80
568_A598_T1.6180.80
397_E604_V1.6170.80
493_S496_G1.6100.80
192_G578_T1.6100.80
359_I452_T1.6100.80
220_S238_P1.6090.79
411_L552_T1.5910.79
302_A441_F1.5810.78
311_V523_S1.5790.78
345_T359_I1.5710.78
567_F613_T1.5700.78
351_A580_I1.5670.78
315_S337_G1.5630.77
249_G453_P1.5530.77
144_G147_V1.5490.77
670_G683_M1.5430.76
729_A763_V1.5410.76
434_L619_L1.5310.76
310_I343_A1.5290.76
348_T750_I1.5270.76
405_H616_T1.5220.75
299_A317_A1.5150.75
294_S571_A1.5130.75
190_V321_F1.5130.75
163_R239_L1.5100.75
220_S223_P1.5060.75
297_A302_A1.5050.75
252_V523_S1.5040.75
272_L619_L1.4990.74
181_N374_L1.4980.74
303_S514_F1.4940.74
456_G465_L1.4850.74
592_L604_V1.4840.74
763_V769_L1.4670.73
470_L753_V1.4660.73
142_T146_R1.4660.73
345_T452_T1.4560.72
468_A622_K1.4530.72
459_L516_L1.4510.72
666_R686_R1.4460.72
332_T364_Y1.4450.72
285_K671_L1.4430.71
274_S281_Q1.4390.71
673_I756_D1.4340.71
364_Y723_T1.4260.70
425_G428_A1.4250.70
507_A536_M1.4170.70
242_A454_A1.4110.70
246_A544_L1.4100.70
266_H416_Y1.4090.70
468_A506_L1.4040.69
415_L418_G1.3960.69
684_L720_E1.3810.68
356_A570_T1.3750.68
459_L463_S1.3750.68
678_D758_S1.3710.67
450_Y565_G1.3660.67
507_A540_A1.3640.67
197_V295_S1.3630.67
490_I494_I1.3610.67
310_I528_S1.3590.67
142_T147_V1.3480.66
639_A763_V1.3470.66
669_R685_V1.3460.66
247_V454_A1.3460.66
428_A533_V1.3430.66
487_Y494_I1.3390.65
741_R745_V1.3360.65
706_C710_G1.3340.65
255_V402_I1.3340.65
198_F598_T1.3260.65
686_R767_D1.3250.65
243_L418_G1.3140.64
356_A598_T1.3130.64
193_L197_V1.3110.64
643_M686_R1.3100.64
502_V528_S1.3100.64
434_L517_S1.3070.64
705_V708_R1.3050.63
298_I579_L1.3050.63
202_I581_I1.3020.63
220_S225_H1.3000.63
266_H616_T1.2880.62
139_W143_H1.2860.62
205_A485_V1.2850.62
371_T588_Y1.2840.62
465_L483_F1.2840.62
375_S720_E1.2800.62
613_T619_L1.2800.62
487_Y497_D1.2780.62
297_A522_N1.2750.62
139_W144_G1.2740.62
269_P456_G1.2690.61
191_A317_A1.2660.61
599_V650_V1.2620.61
416_Y586_G1.2620.61
426_I537_A1.2570.60
345_T519_G1.2560.60
413_F607_G1.2560.60
659_A689_V1.2550.60
508_V662_V1.2530.60
134_P138_R1.2510.60
147_V150_A1.2470.60
528_S594_L1.2450.60
293_S523_S1.2450.60
604_V607_G1.2430.60
272_L306_R1.2400.59
306_R518_I1.2390.59
182_T718_V1.2380.59
451_L760_V1.2380.59
303_S342_I1.2370.59
256_I613_T1.2320.59
268_V434_L1.2310.59
333_L337_G1.2290.59
373_V599_V1.2250.58
248_G482_L1.2240.58
342_I521_G1.2190.58
377_V591_I1.2180.58
333_L350_L1.2170.58
322_G522_N1.2140.58
535_A574_P1.2140.58
247_V762_I1.2140.58
350_L416_Y1.2110.58
133_R136_K1.2030.57
468_A628_E1.2030.57
273_E571_A1.2000.57
658_D661_R1.1990.57
310_I615_Y1.1970.57
353_V523_S1.1960.57
510_K514_F1.1900.56
273_E356_A1.1890.56
375_S721_L1.1890.56
650_V659_A1.1760.55
508_V665_Q1.1750.55
230_F421_V1.1700.55
283_D319_S1.1680.55
284_P361_L1.1670.55
656_A659_A1.1660.55
255_V292_V1.1630.54
731_P754_D1.1630.54
512_V650_V1.1630.54
416_Y593_P1.1620.54
418_G421_V1.1610.54
555_A559_A1.1600.54
143_H684_L1.1600.54
475_P479_A1.1530.54
195_A198_F1.1480.53
197_V201_T1.1470.53
205_A302_A1.1460.53
137_C143_H1.1460.53
145_P150_A1.1450.53
359_I371_T1.1440.53
300_S399_L1.1410.53
489_T494_I1.1390.53
490_I495_A1.1380.53
288_V662_V1.1360.53
600_I732_D1.1340.52
318_G420_G1.1320.52
574_P595_L1.1310.52
372_V376_A1.1280.52
531_L554_S1.1270.52
292_V533_V1.1270.52
486_G491_H1.1260.52
418_G422_V1.1260.52
253_G257_R1.1230.52
136_K139_W1.1200.52
254_L450_Y1.1190.52
347_N400_V1.1140.51
510_K577_A1.1130.51
413_F754_D1.1110.51
478_S577_A1.1090.51
186_L545_V1.1080.51
512_V516_L1.1050.51
334_V626_V1.1030.50
341_G358_E1.1020.50
478_S590_I1.1000.50
137_C645_T1.0990.50
283_D334_V1.0990.50
275_L373_V1.0970.50
271_V584_L1.0960.50
182_T522_N1.0940.50
345_T569_A1.0940.50
248_G296_I1.0930.50
417_A561_V1.0910.50
421_V551_G1.0870.49
438_E621_D1.0870.49
528_S650_V1.0870.49
177_G324_F1.0840.49
196_V599_V1.0840.49
480_T608_L1.0800.49
252_V326_H1.0780.49
272_L370_V1.0770.49
190_V634_L1.0710.48
271_V434_L1.0690.48
210_F382_V1.0680.48
281_Q465_L1.0670.48
423_A427_G1.0660.48
492_S497_D1.0660.48
560_L592_L1.0650.48
268_V312_Q1.0640.48
247_V713_S1.0620.48
517_S573_A1.0590.48
680_V751_P1.0590.48
373_V595_L1.0580.47
684_L724_T1.0580.47
354_M579_L1.0560.47
431_V673_I1.0550.47
283_D300_S1.0530.47
248_G382_V1.0520.47
475_P561_V1.0490.47
746_D766_T1.0450.47
297_A599_V1.0410.46
655_S671_L1.0370.46
527_F576_T1.0360.46
200_I387_L1.0350.46
306_R383_A1.0330.46
704_A708_R1.0290.46
203_F673_I1.0270.45
317_A636_D1.0270.45
205_A299_A1.0210.45
489_T493_S1.0190.45
708_R719_E1.0190.45
193_L422_V1.0180.45
139_W146_R1.0130.45
396_R401_P1.0120.44
414_P418_G1.0120.44
298_I310_I1.0100.44
238_P242_A1.0100.44
351_A354_M1.0090.44
522_N763_V1.0070.44
637_L735_L1.0060.44
337_G362_S1.0050.44
277_V718_V1.0040.44
686_R764_T1.0000.44
309_P525_G0.9980.44
332_T367_T0.9960.43
451_L455_I0.9940.43
271_V618_A0.9940.43
191_A734_N0.9920.43
237_G337_G0.9900.43
240_R247_V0.9880.43
246_A649_T0.9880.43
639_A764_T0.9880.43
535_A655_S0.9870.43
268_V370_V0.9860.43
261_T764_T0.9840.43
673_I722_G0.9830.43
266_H272_L0.9820.43
239_L252_V0.9810.42
477_Q524_G0.9800.42
561_V763_V0.9800.42
456_G461_G0.9770.42
486_G497_D0.9750.42
351_A427_G0.9720.42
408_T530_T0.9720.42
180_L723_T0.9710.42
182_T297_A0.9690.42
292_V508_V0.9690.42
754_D758_S0.9690.42
603_E624_I0.9690.42
735_L771_A0.9660.41
387_L391_A0.9660.41
675_D681_A0.9660.41
514_F517_S0.9640.41
191_A456_G0.9630.41
356_A361_L0.9610.41
300_S402_I0.9610.41
685_V688_D0.9600.41
236_L239_L0.9600.41
483_F563_T0.9580.41
521_G626_V0.9560.41
531_L753_V0.9560.41
491_H494_I0.9520.41
648_D735_L0.9510.41
240_R288_V0.9500.40
180_L329_Y0.9450.40
239_L324_F0.9410.40
421_V600_I0.9400.40
491_H496_G0.9390.40
193_L508_V0.9370.40
233_L508_V0.9350.40
434_L602_S0.9340.39
245_P685_V0.9330.39
175_R186_L0.9330.39
213_T241_Y0.9310.39
650_V665_Q0.9290.39
329_Y371_T0.9290.39
256_I261_T0.9280.39
431_V617_E0.9260.39
539_G625_T0.9240.39
263_I642_V0.9170.38
348_T437_S0.9160.38
189_I657_M0.9130.38
596_A710_G0.9130.38
312_Q349_P0.9130.38
504_V678_D0.9120.38
487_Y496_G0.9120.38
265_G359_I0.9110.38
633_S639_A0.9090.38
252_V297_A0.9040.38
331_R345_T0.9030.38
180_L743_A0.9000.37
189_I425_G0.9000.37
307_E359_I0.8970.37
183_A321_F0.8950.37
199_R306_R0.8940.37
361_L419_L0.8930.37
191_A513_G0.8930.37
332_T670_G0.8910.37
268_V306_R0.8890.37
663_F671_L0.8870.37
454_A620_R0.8860.36
170_R508_V0.8850.36
271_V315_S0.8840.36
363_E655_S0.8840.36
254_L511_V0.8830.36
273_E416_Y0.8820.36
238_P299_A0.8820.36
248_G459_L0.8820.36
497_D508_V0.8760.36
239_L750_I0.8750.36
597_V601_G0.8730.36
568_A576_T0.8720.36
504_V540_A0.8700.36
545_V570_T0.8680.35
486_G494_I0.8680.35
373_V396_R0.8680.35
383_A460_L0.8670.35
275_L360_L0.8670.35
184_A371_T0.8660.35
327_S332_T0.8660.35
192_G587_Q0.8650.35
505_A520_S0.8640.35
268_V535_A0.8630.35
549_F678_D0.8620.35
314_G334_V0.8560.35
273_E380_T0.8530.34
313_I373_V0.8530.34
348_T557_A0.8510.34
421_V710_G0.8510.34
475_P532_Y0.8500.34
417_A651_T0.8490.34
487_Y490_I0.8490.34
307_E579_L0.8480.34
425_G429_A0.8470.34
201_T248_G0.8440.34
301_G307_E0.8440.34
134_P153_A0.8430.34
198_F310_I0.8400.34
704_A707_A0.8380.34
199_R416_Y0.8380.34
526_V587_Q0.8360.33
304_L522_N0.8360.33
247_V501_L0.8360.33
364_Y476_L0.8350.33
252_V433_L0.8340.33
331_R606_Q0.8340.33
263_I342_I0.8340.33
463_S509_L0.8330.33
211_G316_A0.8320.33
641_D762_I0.8300.33
251_I678_D0.8270.33
181_N306_R0.8270.33
223_P245_P0.8260.33
138_R141_R0.8230.33
322_G374_L0.8230.33
572_S606_Q0.8220.33
455_I664_Q0.8210.33
452_T569_A0.8200.33
396_R407_V0.8190.32
596_A714_P0.8170.32
259_T289_Y0.8140.32
689_V763_V0.8140.32
287_A313_I0.8120.32
250_L489_T0.8110.32
463_S505_A0.8110.32
359_I560_L0.8110.32
412_E416_Y0.8100.32
521_G531_L0.8100.32
708_R711_G0.8100.32
194_G596_A0.8090.32
331_R519_G0.8080.32
190_V193_L0.8070.32
263_I307_E0.8070.32
359_I521_G0.8070.32
145_P157_T0.8060.32
530_T566_V0.8050.32
244_V592_L0.8050.32
186_L292_V0.8050.32
509_L512_V0.8030.32
337_G528_S0.8020.32
235_P545_V0.8000.31
453_P460_L0.8000.31
693_V712_Q0.8000.31
265_G618_A0.7990.31
271_V613_T0.7990.31
135_G138_R0.7990.31
179_R733_T0.7980.31
272_L535_A0.7940.31
233_L544_L0.7930.31
247_V508_V0.7920.31
452_T519_G0.7910.31
242_A436_A0.7910.31
311_V558_Y0.7900.31
324_F676_A0.7860.31
292_V459_L0.7840.31
459_L500_L0.7830.30
378_T381_A0.7810.30
639_A695_V0.7800.30
488_G504_V0.7790.30
197_V321_F0.7780.30
334_V449_G0.7780.30
302_A452_T0.7750.30
373_V572_S0.7730.30
481_W526_V0.7730.30
646_D649_T0.7720.30
361_L578_T0.7710.30
687_S768_V0.7700.30
684_L692_L0.7690.30
230_F600_I0.7690.30
519_G569_A0.7690.30
270_E537_A0.7680.30
370_V686_R0.7680.30
456_G615_Y0.7680.30
525_G529_P0.7670.30
434_L452_T0.7670.30
456_G590_I0.7670.30
209_F452_T0.7660.30
625_T746_D0.7660.30
146_R150_A0.7650.29
268_V273_E0.7640.29
559_A642_V0.7640.29
610_D639_A0.7630.29
307_E452_T0.7610.29
671_L697_G0.7600.29
661_R717_A0.7600.29
236_L251_I0.7590.29
527_F558_Y0.7580.29
229_L232_A0.7580.29
562_G574_P0.7580.29
434_L574_P0.7580.29
378_T741_R0.7570.29
380_T624_I0.7560.29
482_L523_S0.7530.29
459_L708_R0.7530.29
211_G311_V0.7530.29
577_A603_E0.7520.29
463_S673_I0.7510.29
399_L402_I0.7460.28
352_G358_E0.7450.28
209_F273_E0.7440.28
565_G593_P0.7430.28
306_R616_T0.7430.28
418_G487_Y0.7410.28
458_A499_T0.7410.28
266_H539_G0.7400.28
506_L566_V0.7390.28
537_A613_T0.7360.28
246_A667_S0.7360.28
153_A772_Y0.7360.28
192_G408_T0.7350.28
232_A443_D0.7350.28
336_A582_F0.7330.28
383_A518_I0.7330.28
459_L717_A0.7320.28
374_L618_A0.7310.28
168_S172_F0.7300.28
142_T145_P0.7300.28
459_L651_T0.7290.28
281_Q614_I0.7280.27
186_L459_L0.7270.27
544_L732_D0.7260.27
209_F423_A0.7260.27
463_S712_Q0.7250.27
367_T588_Y0.7240.27
291_T296_I0.7230.27
302_A527_F0.7230.27
673_I764_T0.7230.27
340_S375_S0.7220.27
637_L641_D0.7210.27
399_L584_L0.7210.27
418_G596_A0.7210.27
246_A681_A0.7210.27
362_S765_R0.7200.27
242_A509_L0.7180.27
591_I618_A0.7170.27
265_G527_F0.7160.27
139_W150_A0.7140.27
414_P738_L0.7140.27
324_F713_S0.7130.27
537_A565_G0.7110.27
414_P599_V0.7110.27
680_V726_V0.7110.27
385_S684_L0.7100.27
367_T387_L0.7100.27
192_G260_T0.7100.27
489_T492_S0.7100.27
661_R665_Q0.7100.27
210_F775_I0.7080.26
505_A604_V0.7070.26
269_P560_L0.7060.26
321_F740_D0.7060.26
359_I510_K0.7050.26
230_F454_A0.7040.26
470_L554_S0.7040.26
646_D771_A0.7040.26
139_W207_A0.7040.26
310_I531_L0.7030.26
604_V627_Q0.7030.26
348_T597_V0.7020.26
192_G556_G0.7020.26
738_L763_V0.6980.26
520_S605_A0.6970.26
189_I250_L0.6960.26
431_V573_A0.6960.26
543_V555_A0.6950.26
641_D674_V0.6940.26
376_A567_F0.6920.26
363_E615_Y0.6910.26
676_A679_T0.6890.25
331_R748_G0.6890.25
201_T244_V0.6880.25
132_G135_G0.6870.25
171_F549_F0.6870.25
193_L208_V0.6860.25
197_V770_A0.6860.25
377_V595_L0.6850.25
383_A614_I0.6850.25
196_V315_S0.6840.25
335_A356_A0.6840.25
713_S717_A0.6830.25
359_I527_F0.6830.25
451_L651_T0.6820.25
419_L432_R0.6810.25
571_A593_P0.6810.25
269_P479_A0.6800.25
413_F488_G0.6800.25
189_I717_A0.6800.25
586_G614_I0.6800.25
380_T576_T0.6790.25
599_V603_E0.6790.25
460_L517_S0.6730.25
709_D713_S0.6720.25
134_P137_C0.6700.25
242_A657_M0.6700.25
649_T653_G0.6680.24
262_A283_D0.6680.24
661_R667_S0.6680.24
343_A518_I0.6680.24
531_L567_F0.6670.24
521_G616_T0.6670.24
365_A723_T0.6670.24
318_G746_D0.6670.24
222_A545_V0.6650.24
162_H371_T0.6650.24
420_G454_A0.6640.24
457_G543_V0.6640.24
340_S378_T0.6630.24
484_G540_A0.6610.24
534_G538_G0.6610.24
524_G580_I0.6600.24
272_L742_M0.6600.24
133_R137_C0.6590.24
143_H462_V0.6570.24
365_A369_V0.6560.24
370_V564_A0.6560.24
434_L519_G0.6560.24
647_V658_D0.6560.24
265_G374_L0.6550.24
353_V412_E0.6540.24
530_T554_S0.6540.24
306_R523_S0.6530.24
659_A662_V0.6530.24
220_S642_V0.6530.24
240_R417_A0.6510.24
275_L748_G0.6500.24
173_L504_V0.6500.24
211_G344_A0.6500.24
644_S764_T0.6500.24
487_Y493_S0.6480.23
275_L568_A0.6470.23
164_S252_V0.6460.23
178_V762_I0.6450.23
382_V740_D0.6450.23
193_L243_L0.6440.23
724_T763_V0.6430.23
132_G136_K0.6430.23
545_V553_A0.6430.23
373_V384_R0.6430.23
589_T684_L0.6420.23
561_V565_G0.6420.23
298_I587_Q0.6420.23
517_S606_Q0.6410.23
471_L509_L0.6410.23
276_M765_R0.6400.23
733_T753_V0.6390.23
142_T150_A0.6380.23
586_G593_P0.6380.23
399_L477_Q0.6370.23
138_R142_T0.6370.23
299_A714_P0.6370.23
669_R690_E0.6360.23
572_S605_A0.6340.23
413_F514_F0.6340.23
656_A727_V0.6330.23
132_G137_C0.6330.23
299_A557_A0.6330.23
472_D602_S0.6320.23
379_A564_A0.6310.23
658_D667_S0.6300.23
561_V733_T0.6290.23
655_S658_D0.6290.23
705_V711_G0.6260.22
709_D712_Q0.6260.22
372_V735_L0.6250.22
192_G581_I0.6250.22
373_V520_S0.6250.22
671_L686_R0.6250.22
475_P485_V0.6240.22
261_T441_F0.6230.22
193_L418_G0.6230.22
508_V636_D0.6230.22
250_L288_V0.6220.22
671_L743_A0.6220.22
649_T674_V0.6220.22
456_G486_G0.6200.22
270_E316_A0.6190.22
342_I442_Q0.6180.22
500_L540_A0.6170.22
703_V709_D0.6160.22
251_I645_T0.6150.22
659_A666_R0.6150.22
641_D752_I0.6150.22
430_V514_F0.6150.22
596_A693_V0.6150.22
189_I496_G0.6150.22
513_G641_D0.6140.22
383_A580_I0.6140.22
437_S515_S0.6130.22
235_P512_V0.6120.22
332_T365_A0.6120.22
564_A595_L0.6110.22
182_T228_N0.6100.22
269_P518_I0.6090.22
171_F659_A0.6090.22
345_T441_F0.6070.22
307_E580_I0.6060.22
533_V566_V0.6060.22
486_G647_V0.6030.21
608_L710_G0.6010.21
293_S318_G0.6010.21
408_T413_F0.6010.21
733_T745_V0.6010.21
423_A452_T0.6010.21
248_G553_A0.6000.21
423_A519_G0.6000.21
224_I733_T0.6000.21
264_R359_I0.5990.21
435_Y438_E0.5980.21
648_D656_A0.5980.21
473_A763_V0.5980.21
441_F764_T0.5980.21
641_D722_G0.5960.21
186_L299_A0.5920.21
417_A488_G0.5910.21
361_L575_L0.5910.21
199_R293_S0.5910.21
707_A712_Q0.5900.21
172_F516_L0.5900.21
263_I461_G0.5900.21
260_T594_L0.5890.21
208_V662_V0.5870.21
364_Y367_T0.5870.21
275_L317_A0.5860.21
349_P525_G0.5850.21
465_L608_L0.5850.21
221_F224_I0.5830.21
423_A537_A0.5830.21
438_E531_L0.5780.20
421_V553_A0.5770.20
351_A579_L0.5760.20
435_Y592_L0.5760.20
507_A621_D0.5750.20
704_A711_G0.5750.20
459_L549_F0.5740.20
372_V728_T0.5740.20
330_T599_V0.5730.20
487_Y659_A0.5730.20
380_T607_G0.5720.20
250_L637_L0.5720.20
339_G738_L0.5720.20
259_T285_K0.5710.20
546_N594_L0.5710.20
229_L508_V0.5700.20
370_V585_T0.5690.20
343_A568_A0.5690.20
345_T423_A0.5690.20
463_S488_G0.5690.20
287_A337_G0.5680.20
385_S513_G0.5680.20
460_L674_V0.5680.20
371_T428_A0.5680.20
654_T662_V0.5680.20
447_L459_L0.5670.20
458_A469_V0.5670.20
652_V658_D0.5660.20
504_V679_T0.5660.20
301_G355_F0.5660.20
309_P349_P0.5640.20
190_V665_Q0.5640.20
239_L257_R0.5640.20
396_R572_S0.5630.20
668_H764_T0.5630.20
470_L614_I0.5630.20
289_Y608_L0.5630.20
436_A505_A0.5620.20
162_H326_H0.5610.20
304_L316_A0.5610.20
288_V513_G0.5600.20
564_A574_P0.5600.20
306_R312_Q0.5600.20
571_A598_T0.5590.20
678_D763_V0.5580.19
639_A643_M0.5580.19
267_G761_G0.5570.19
359_I748_G0.5570.19
459_L716_T0.5570.19
281_Q481_W0.5570.19
430_V615_Y0.5560.19
457_G530_T0.5560.19
145_P435_Y0.5560.19
456_G537_A0.5550.19
438_E618_A0.5540.19
439_H531_L0.5540.19
322_G330_T0.5530.19
433_L537_A0.5530.19
220_S281_Q0.5520.19
204_A208_V0.5520.19
442_Q446_D0.5520.19
481_W498_L0.5520.19
380_T588_Y0.5520.19
266_H625_T0.5520.19
255_V476_L0.5510.19
244_V773_D0.5500.19
555_A570_T0.5500.19
324_F417_A0.5490.19
141_R144_G0.5480.19
141_R147_V0.5480.19
527_F536_M0.5480.19
186_L196_V0.5480.19
537_A566_V0.5480.19
306_R423_A0.5470.19
431_V605_A0.5470.19
243_L642_V0.5450.19
538_G542_G0.5440.19
428_A647_V0.5440.19
490_I666_R0.5440.19
269_P343_A0.5430.19
250_L718_V0.5420.19
231_G418_G0.5390.19
229_L709_D0.5380.19
322_G741_R0.5370.19
475_P528_S0.5370.19
440_L445_W0.5370.19
483_F537_A0.5360.19
735_L760_V0.5360.19
221_F544_L0.5360.19
233_L378_T0.5340.18
549_F592_L0.5340.18
502_V513_G0.5340.18
419_L473_A0.5340.18
361_L594_L0.5330.18
703_V707_A0.5330.18
257_R450_Y0.5310.18
573_A618_A0.5310.18
181_N625_T0.5310.18
137_C149_A0.5310.18
333_L588_Y0.5310.18
240_R283_D0.5310.18
437_S514_F0.5310.18
504_V729_A0.5300.18
384_R616_T0.5300.18
212_A236_L0.5300.18
349_P615_Y0.5290.18
313_I568_A0.5280.18
471_L597_V0.5270.18
137_C140_A0.5260.18
459_L486_G0.5260.18
275_L615_Y0.5250.18
272_L573_A0.5250.18
439_H592_L0.5250.18
461_G582_F0.5250.18
192_G767_D0.5240.18
378_T433_L0.5240.18
143_H688_D0.5240.18
462_V664_Q0.5240.18
315_S462_V0.5230.18
498_L655_S0.5220.18
184_A336_A0.5220.18
489_T497_D0.5210.18
260_T441_F0.5210.18
314_G554_S0.5190.18
319_S362_S0.5190.18
293_S576_T0.5190.18
333_L363_E0.5190.18
145_P262_A0.5180.18
608_L734_N0.5180.18
375_S379_A0.5180.18
238_P462_V0.5180.18
225_H422_V0.5180.18
367_T555_A0.5180.18
602_S746_D0.5180.18
565_G658_D0.5170.18
197_V548_A0.5170.18
533_V690_E0.5160.18
423_A460_L0.5160.18
330_T357_L0.5150.18
415_L541_F0.5150.18
443_D650_V0.5150.18
150_A484_G0.5140.18
298_I531_L0.5140.18
689_V724_T0.5130.18
223_P732_D0.5130.18
644_S767_D0.5130.18
510_K584_L0.5120.18
671_L767_D0.5120.18
236_L676_A0.5120.18
316_A357_L0.5110.18
523_S757_G0.5100.18
280_G299_A0.5090.18
347_N461_G0.5090.18
509_L763_V0.5090.18
461_G555_A0.5080.17
684_L725_N0.5080.17
168_S596_A0.5080.17
414_P422_V0.5080.17
405_H422_V0.5070.17
706_C711_G0.5070.17
300_S729_A0.5060.17
656_A763_V0.5060.17
524_G619_L0.5040.17
141_R155_G0.5040.17
459_L488_G0.5040.17
527_F618_A0.5040.17
572_S748_G0.5030.17
390_T744_R0.5030.17
204_A552_T0.5020.17
601_G738_L0.5010.17
674_V695_V0.5010.17
375_S727_V0.5000.17
196_V271_V0.5000.17
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
3orgA 2 0.654 100 0.522 Contact Map
4eneA 2 0.5492 100 0.637 Contact Map
3nd0A 2 0.5303 100 0.644 Contact Map
1jcnA 6 0.2374 100 0.865 Contact Map
3usbA 4 0.2854 100 0.887 Contact Map
2d4zA 3 0.1843 99.9 0.898 Contact Map
1vrdA 3 0.1301 99.9 0.902 Contact Map
2pfiA 2 0.1768 99.8 0.914 Contact Map
2j9lA 3 0.1881 99.8 0.915 Contact Map
2cu0A 4 0.1326 99.8 0.915 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.0154 seconds.